Based off of prior QC (“20201025_DECAMP2_Novartis_QC_Bronch.Rmd”), we have identified several poor quality samples. We will remove these samples prior to any downstream analysis.
# Load library:
library(plyr)
library(SummarizedExperiment)
library(readxl)
library(dplyr)
library(ggplot2)
library(pheatmap)
library("RColorBrewer")
library(DESeq2)
library(knitr)
library(kableExtra)
library(enrichR)
library(biomaRt)
library(affy)
library(limma)
set.seed("12345")
# Load data:
se <- readRDS("/restricted/projectnb/pulmseq/Novartis/processing/work/28/da9dcb4ebb5f902c53fff1bc1ebdc2/Novartis_Gene_Expression.rds")
colnames(se) <- gsub(pattern = "_.*", "", colnames(se))
# Load annotation:
# Matches sample ID to kitnumber + Has batch info
annotManifest <- read_excel("/restricted/projectnb/pulmseq/Novartis/annotation/Novartis_RNASeq_run_manifest.xlsx")
# Matches sample ID to sample type/RIN (received from Jack, 8/24/20)
annotSampleEM0 <- read_excel("/restricted/projectnb/camplab/home/ykoga07/DECAMP/Novartis/Data/Annotation/RNA_data_for_Yusuke_08_24_20.xlsx", sheet = "EM0", skip = 2)
annotSampleEM5 <- read_excel("/restricted/projectnb/camplab/home/ykoga07/DECAMP/Novartis/Data/Annotation/RNA_data_for_Yusuke_08_24_20.xlsx", sheet = "EM5", skip = 2)
annotSampleEM6 <- read_excel("/restricted/projectnb/camplab/home/ykoga07/DECAMP/Novartis/Data/Annotation/RNA_data_for_Yusuke_08_24_20.xlsx", sheet = "EM6", skip = 2)
annotSampleEM8 <- read_excel("/restricted/projectnb/camplab/home/ykoga07/DECAMP/Novartis/Data/Annotation/RNA_data_for_Yusuke_08_24_20.xlsx", sheet = "EM8", skip = 3)
annotSampleEM15 <- read_excel("/restricted/projectnb/camplab/home/ykoga07/DECAMP/Novartis/Data/Annotation/RNA_data_for_Yusuke_08_24_20.xlsx", sheet = "EM15", skip = 3)
annotSampleEM16 <- read_excel("/restricted/projectnb/camplab/home/ykoga07/DECAMP/Novartis/Data/Annotation/RNA_data_for_Yusuke_08_24_20.xlsx", sheet = "EM16", skip = 3)
annotSampleN1 <- read_excel("/restricted/projectnb/camplab/home/ykoga07/DECAMP/Novartis/Data/Annotation/RNA_data_for_Yusuke_08_24_20.xlsx", sheet = "N1", skip = 3)
annotSampleN2 <- read_excel("/restricted/projectnb/camplab/home/ykoga07/DECAMP/Novartis/Data/Annotation/RNA_data_for_Yusuke_08_24_20.xlsx", sheet = "N2", skip = 3)
# Combine Jack's sample-based annotation file into one dataframe
annotSampleEM0 <- annotSampleEM0[, c(
"RNA Sample ID", "DECAMP #",
"Sample ID", "Kit Number", "Original Sample Type",
"Isolation Date", "RIN", "DV200 (%)"
)]
colnames(annotSampleEM0) <- c(
"RNA Sample ID", "DECAMP #",
"Sample ID", "Kit Number", "Sample Type",
"Isolation Date", "RIN", "DV200 (%)"
)
annotSampleEM5 <- annotSampleEM5[, c(
"RNA Sample ID", "DECAMP #",
"Patient ID", "Patient ID", "Sample Type",
"Isolation Date", "RIN", "DV200 (%)"
)]
colnames(annotSampleEM5) <- c(
"RNA Sample ID", "DECAMP #",
"Sample ID", "Kit Number", "Sample Type",
"Isolation Date", "RIN", "DV200 (%)"
)
annotSampleEM6 <- annotSampleEM6[, c(
"RNA Sample ID", "DECAMP #",
"Sample ID", "Kit Number", "Sample Type",
"Isolation Date", "RIN", "DV200 (%)"
)]
colnames(annotSampleEM6) <- c(
"RNA Sample ID", "DECAMP #",
"Sample ID", "Kit Number", "Sample Type",
"Isolation Date", "RIN", "DV200 (%)"
)
annotSampleEM8 <- annotSampleEM8[, c(
"RNA Sample ID", "DECAMP #",
"Sample ID", "Original Sample ID", "Sample Type",
"Isolation Date", "RIN", "DV200 (%)"
)]
colnames(annotSampleEM8) <- c(
"RNA Sample ID", "DECAMP #",
"Sample ID", "Kit Number", "Sample Type",
"Isolation Date", "RIN", "DV200 (%)"
)
annotSampleEM15 <- annotSampleEM15[, c(
"RNA Sample ID", "DECAMP #",
"Sample ID", "Kit Number", "Sample Type",
"Isolation Date", "RIN", "DV200 (%)"
)]
colnames(annotSampleEM15) <- c(
"RNA Sample ID", "DECAMP #",
"Sample ID", "Kit Number", "Sample Type",
"Isolation Date", "RIN", "DV200 (%)"
)
annotSampleEM16 <- annotSampleEM16[, c(
"RNA Sample ID", "DECAMP #",
"Sample ID", "Kit Number", "Sample Type",
"Isolation Date", "RIN", "DV200 (%)"
)]
colnames(annotSampleEM16) <- c(
"RNA Sample ID", "DECAMP #",
"Sample ID", "Kit Number", "Sample Type",
"Isolation Date", "RIN", "DV200 (%)"
)
annotSampleN1 <- annotSampleN1[, c(
"RNA Sample ID", "DECAMP #",
"Sample ID", "Kit Number", "Sample Type",
"Isolation Date", "RIN", "DV200 (%)"
)]
colnames(annotSampleN1) <- c(
"RNA Sample ID", "DECAMP #",
"Sample ID", "Kit Number", "Sample Type",
"Isolation Date", "RIN", "DV200 (%)"
)
annotSampleN2 <- annotSampleN2[, c(
"RNA Sample ID", "DECAMP #",
"Sample ID", "Kit Number", "Sample Type",
"Isolation Date", "RIN", "DV200 (%)"
)]
colnames(annotSampleN2) <- c(
"RNA Sample ID", "DECAMP #",
"Sample ID", "Kit Number", "Sample Type",
"Isolation Date", "RIN", "DV200 (%)"
)
allAnnotSamples <- ls()[grep("annotSample", ls())]
annotSample <- as.data.frame(matrix(ncol = 8))
colnames(annotSample) <- c(
"RNA Sample ID", "DECAMP #",
"Sample ID", "Kit Number", "Sample Type",
"Isolation Date", "RIN", "DV200 (%)"
)
# Combine
for (x in allAnnotSamples) {
annotSamples <- get(x)
annotSamples$`Isolation Date` <- as.character(annotSamples$`Isolation Date`)
annotSample <- rbind(annotSample, annotSamples)
}
annotSample <- annotSample[-which(is.na(annotSample$`RNA Sample ID`)), ]
annotSample <- annotSample[-which(is.na(annotSample$`Sample Type`)), ]
annotSample <- annotSample[-which(duplicated(annotSample$`RNA Sample ID`)), ]
# Save which samples had wrong rRNA peak when checking RIN
wrongRRNA.ix <- grep(pattern = "rong rRNA peak", annotSample$RIN)
annotSample$wrongRNAPeak <- 0
annotSample$wrongRNAPeak[wrongRRNA.ix] <- 1
# Edit RIN section to convert into numeric vector
annotSample$RIN <- gsub(pattern = "(wrong rRNA peak)", replacement = "", annotSample$RIN, fixed = TRUE)
annotSample$RIN <- gsub(pattern = "(wrong RNA peak)", replacement = "", annotSample$RIN, fixed = TRUE)
annotSample$RIN <- gsub(pattern = "(wrong rRNA peaks)", replacement = "", annotSample$RIN, fixed = TRUE)
annotSample$RIN <- gsub(pattern = "(Wrong rRNA peak)", replacement = "", annotSample$RIN, fixed = TRUE)
annotSample$RIN <- gsub(pattern = "(Wrong rRNA peaks)", replacement = "", annotSample$RIN, fixed = TRUE)
annotSample$RIN <- gsub(pattern = "\\/NA", replacement = "", annotSample$RIN)
annotSample$RIN <- gsub(pattern = ".*\\/", replacement = "", annotSample$RIN)
annotSample$RIN <- as.numeric(annotSample$RIN)
# There is a "29", probably 2.9, will ask Jack
annotSample$RIN[annotSample$RIN == 29] <- 2.9
# Consolidate nasal/bronch terms
annotSample$`Sample Type` <- gsub(pattern = ".*Bronch.*", replacement = "Bronchial Brushings", annotSample$`Sample Type`)
annotSample$`Sample Type` <- gsub(pattern = ".*Nasal.*", replacement = "Nasal Brushings", annotSample$`Sample Type`)
annotManifest <- filter(annotManifest, Run == "Run 1")
annotSample <- annotSample[annotSample$`RNA Sample ID` %in% annotManifest$Sample, ]
annotSample <- annotSample[match(annotSample$`RNA Sample ID`, annotManifest$Sample), ]
# Removing duplicate column
annotManifest$`Kit Number` <- NULL
annot <- cbind(annotManifest, annotSample)
# Clinical info:
# Matches kitnumber to randID, "Novartis_datadump"
annotDataDump2 <- read_excel("/restricted/projectnb/decamp/annotation/20200920/FullDECAMP2_DataDump_20200920.xlsx", sheet = "_D2CASEMAP", )
# randID to demographics info, "Novartis_datadump"
annotDataDump3 <- read_excel("/restricted/projectnb/decamp/annotation/20200920/FullDECAMP2_DataDump_20200920.xlsx", sheet = "_D2DEMO")
# randID to age/smoking info, "Novartis_datadump"
annotDataDump4 <- read_excel("/restricted/projectnb/decamp/annotation/20200920/FullDECAMP2_DataDump_20200920.xlsx", sheet = "_D2ELIGCHECK")
# randID to FEV/FVC, "Novartis_datadump"
annotDataDump5 <- read_excel("/restricted/projectnb/decamp/annotation/20200920/FullDECAMP2_DataDump_20200920.xlsx", sheet = "_D2PFT")
annotDataDump5 <- filter(annotDataDump5, timepoint == "Baseline Visit")
# Combine annotation info
annotA <- merge(merge(annotDataDump2, annotDataDump3, by.x = "randID", by.y = "randID"), annotDataDump4, by.x = "randID", by.y = "randID")
annotA <- merge(annotA, annotDataDump5, by.x = "randID", by.y = "randID")
# Removing patient "4796-053" as "Pacific Islander" for time being
annotA <- annotA[!(duplicated(annotA$randID)), ]
annot <- merge(annot, annotA, by.x = "Kit Number", by.y = "kitnumber", all.x = TRUE)
annotBronch <- annot[annot$`Sample Type` == "Bronchial Brushings", ]
annotNasal <- annot[annot$`Sample Type` == "Nasal Brushings", ]
uniquePatients <- length(unique(annot$`Kit Number`))
numBronch <- length(unique(annotBronch$Sample))
numNasal <- length(unique(annotNasal$Sample))
bothBronchNasal <- length(intersect(annotBronch$`Kit Number`, annotNasal$`Kit Number`))
#Steiling signature genes
steilingGenes <- read_excel("/restricted/projectnb/camplab/home/ykoga07/DECAMP/Novartis/Analysis/1stPass/Steiling_2013_Genelist.xlsx", sheet = "GeneList", col_names = FALSE)
There are 280 samples and 201 unique patients in the dataset. 80 are nasal samples. There are 79 patients that have both bronchial and nasal samples.
# Samples flagged by Novartis as poor quality:
# flaggedByNovartis <- c(
# "EM15-14", "EM15-31", "EM15-64", "EM15-85", "EM16-194", "EM16-195",
# "EM16-228", "EM5-100", "EM8-112", "EM8-130", "EM8-158", "EM8-171",
# "EM8-26", "EM8-55", "EM8-66", "N1-115", "N1-119", "N1-125",
# "N1-139", "N1-25", "N1-40", "N1-55", "N1-63", "N1-64",
# "N1-67", "N1-81", "N1-83", "N1-84", "N1-94", "N2-10",
# "N2-15", "N2-18", "N2-30", "N2-31", "N2-22", "N2-28"
# )
poorQuality <- read.table("/restricted/projectnb/camplab/home/ykoga07/DECAMP/Novartis/Analysis/QC/20201026_PoorQuality_Bronch.txt")
seBronch <- se[, which(colnames(se) %in% annotBronch$`RNA Sample ID`)]
orig.num.samples <- ncol(seBronch)
#Remove:
seBronch <- seBronch[,!colnames(seBronch) %in% poorQuality$x]
filt.num.samples <- ncol(seBronch)
annotBronch <- annotBronch[annotBronch$`RNA Sample ID` %in% colnames(se), ]
# reorder
annotBronch <- annotBronch[match(colnames(seBronch), annotBronch$`RNA Sample ID`), ]
coldataBronch <- colData(seBronch)
annotBronch$TIN <- colData(seBronch)$RSeQC_TIN_mean
Originally, there were 200 samples. Upon filtering, we will use 173 samples for downstream analysis.
counts <- assay(seBronch)
rownames(counts) <- rowRanges(seBronch)$external_gene_id
counts <- apply(counts, 1:2, function(x) {
return(as.integer(x))
})
# arglist <- list(x=annotBronch$FEV_RS_PER,y=annotBronch$FEV_FVC)
# statusfxn <- function(x,y) {
# if (x < 80 && y < 0.7) {
# return("COPD")
# } else {
# return("NO_COPD")
# }
# }
# copd.status <- sapply(arglist, statusfxn, x = x, y = y)
copd.status <- c()
for(x in 1:nrow(annotBronch)){
if(annotBronch[x, "FEV_RS_PER"] < 80 &&
annotBronch[x, "FEV_FVC"] < 0.7){
copd.status <- c(copd.status, "COPD")
}else{
copd.status <- c(copd.status, "NO_COPD")
}
}
annotBronch$COPD_status <- as.factor(copd.status)
annotBronch$GRPB_SMK_STS <- gsub(" ", "_", annotBronch$GRPB_SMK_STS)
no.smk.status.ix <- which(is.na(annotBronch$GRPB_SMK_STS))
counts <- counts[, -no.smk.status.ix]
annotBronch <- annotBronch[-no.smk.status.ix, ]
2 samples were removed due to lack of smoker status.
General annotation data of patients were compared between those of which samples of FEV1 predicted < 80 (COPD) and FEV1 predicted > 80 (NO COPD).
#Rename race
annotBronch$RACE_CAT_TXT <- gsub("Unknown","Not Reported",annotBronch$RACE_CAT_TXT)
annotBronch$RACE_CAT_TXT <- gsub("Black or Afr. American",
"Black/African American",annotBronch$RACE_CAT_TXT)
annotBronch$RACE_CAT_TXT <- gsub("Native Hawaiian or Other Pacific Islander",
"Pacific Islander",annotBronch$RACE_CAT_TXT)
annotBronch$RACE_CAT_TXT <- gsub("American Indian or Alaska Native",
"Native American",annotBronch$RACE_CAT_TXT)
annotBronch$RACE_CAT_TXT <- as.factor(annotBronch$RACE_CAT_TXT)
annotBronch_COPD <- annotBronch[annotBronch$COPD_status == "COPD", ]
annotBronch_NO_COPD <- annotBronch[annotBronch$COPD_status == "NO_COPD", ]
lab <- c(
rep("Retained", length(annotBronch_COPD$GRPB_SMK_STS)),
rep("Removed", length(annotBronch_NO_COPD$GRPB_SMK_STS))
)
# AGE
mean.age <- mean(annotBronch_COPD$AGE)
sd.age <- sd(annotBronch_COPD$AGE)
age <- paste0(signif(mean.age, 3), " +/- ", signif(sd.age, 3))
mean.age.rm <- mean(annotBronch_NO_COPD$AGE)
sd.age.rm <- sd(annotBronch_NO_COPD$AGE)
age.rm <- paste0(signif(mean.age.rm, 3), " +/- ", signif(sd.age.rm, 3))
age.pvalue <- signif(wilcox.test(annotBronch_COPD$AGE, annotBronch_NO_COPD$AGE)$p.value, 3)
demo.table <- c(age, age.rm, age.pvalue)
# Gender
gstatus <- c(annotBronch_COPD$PERSON_GENDER, annotBronch_NO_COPD$PERSON_GENDER)
male.ct <- sum(annotBronch_COPD$PERSON_GENDER == "Male Gender")
male.pct <- signif(male.ct / length(annotBronch_COPD$PERSON_GENDER), 3) * 100
male <- paste0("Male: ", male.ct, "(", male.pct, "%)")
male.ct.rm <- sum(annotBronch_NO_COPD$PERSON_GENDER == "Male Gender")
male.pct.rm <- signif(male.ct.rm / length(annotBronch_NO_COPD$PERSON_GENDER), 3) * 100
male.rm <- paste0("Male: ", male.ct.rm, "(", male.pct.rm, "%)")
gender.pvalue <- signif(chisq.test(table(lab, gstatus))$p.value, 3)
demo.table <- rbind(demo.table, c(male, male.rm, gender.pvalue))
# FEV1 predicted
mean.fev1p <- mean(annotBronch_COPD$FEV_RS_PER)
sd.fev1p <- sd(annotBronch_COPD$FEV_RS_PER)
fev1p <- paste0(signif(mean.fev1p, 3), " +/- ", signif(sd.fev1p, 3))
mean.fev1p.rm <- mean(annotBronch_NO_COPD$FEV_RS_PER)
sd.fev1p.rm <- sd(annotBronch_NO_COPD$FEV_RS_PER)
fev1p.rm <- paste0(signif(mean.fev1p.rm, 3), " +/- ", signif(sd.fev1p.rm, 3))
fev1p.pvalue <- signif(wilcox.test(annotBronch_COPD$FEV_RS_PER, annotBronch_NO_COPD$FEV_RS_PER)$p.value, 3)
demo.table <- rbind(demo.table, c(fev1p, fev1p.rm, fev1p.pvalue))
# FEVFVC
mean.fevfvc <- mean(annotBronch_COPD$FEV_FVC)
sd.fevfvc <- sd(annotBronch_COPD$FEV_FVC)
fevfvc <- paste0(signif(mean.fevfvc, 3), " +/- ", signif(sd.fevfvc, 3))
mean.fevfvc.rm <- mean(annotBronch_NO_COPD$FEV_FVC)
sd.fevfvc.rm <- sd(annotBronch_NO_COPD$FEV_FVC)
fevfvc.rm <- paste0(signif(mean.fevfvc.rm, 3), " +/- ", signif(sd.fevfvc.rm, 3))
fevfvc.pvalue <- signif(wilcox.test(annotBronch_COPD$FEV_FVC, annotBronch_NO_COPD$FEV_FVC)$p.value, 3)
demo.table <- rbind(demo.table, c(fevfvc, fevfvc.rm, fevfvc.pvalue))
# TIN
mean.tin <- mean(annotBronch_COPD$TIN)
sd.tin <- sd(annotBronch_COPD$TIN)
tin <- paste0(signif(mean.tin, 3), " +/- ", signif(sd.tin, 3))
mean.tin.rm <- mean(annotBronch_NO_COPD$TIN)
sd.tin.rm <- sd(annotBronch_NO_COPD$TIN)
tin.rm <- paste0(signif(mean.tin.rm, 3), " +/- ", signif(sd.tin.rm, 3))
tin.pvalue <- signif(wilcox.test(annotBronch_COPD$TIN, annotBronch_NO_COPD$TIN)$p.value, 3)
demo.table <- rbind(demo.table, c(tin, tin.rm, tin.pvalue))
# Smoking Status
smk <- c(annotBronch_COPD$GRPB_SMK_STS, annotBronch_NO_COPD$GRPB_SMK_STS)
annotBronch_COPD$GRPB_SMK_STS <- gsub(" ", "_", annotBronch_COPD$GRPB_SMK_STS)
annotBronch_NO_COPD$GRPB_SMK_STS <- gsub(" ", "_", annotBronch_NO_COPD$GRPB_SMK_STS)
smkstatus.na <- sum(is.na(annotBronch_COPD$GRPB_SMK_STS == "Current_Smoker"))
smkstatus.ct <- sum(annotBronch_COPD[!is.na(annotBronch_COPD$GRPB_SMK_STS), ]$GRPB_SMK_STS == "Current_Smoker")
smkstatus.pct <- signif(smkstatus.ct / nrow(annotBronch_COPD[!is.na(annotBronch_COPD$GRPB_SMK_STS), ]), 3) * 100
smkstatus <- paste0("Current: ", smkstatus.ct, "(", smkstatus.pct, "%)")
smkstatus.ct.rm <- sum(annotBronch_NO_COPD$GRPB_SMK_STS == "Current_Smoker")
smkstatus.pct.rm <- signif(smkstatus.ct.rm / length(annotBronch_NO_COPD$GRPB_SMK_STS), 3) * 100
smkstatus.rm <- paste0("Current: ", smkstatus.ct.rm, "(", smkstatus.pct.rm, "%)")
smkstatus.pvalue <- signif(chisq.test(table(lab, smk))$p.value, 3)
demo.table <- rbind(demo.table, c(smkstatus, smkstatus.rm, smkstatus.pvalue))
rownames(demo.table) <- c("Age", "Gender", "FEV1 Predicted(%)" , "FEV1/FVC", "TIN", "Smoking Status")
colnames(demo.table) <- c("COPD", "NO COPD", "p-value")
copd.race.table <- as.data.frame(table(annotBronch_COPD$RACE_CAT_TXT))
rownames(copd.race.table) <- copd.race.table$Var1
copd.race.table$Var1 <- NULL
nocopd.race.table <- as.data.frame(table(annotBronch_NO_COPD$RACE_CAT_TXT))
rownames(nocopd.race.table) <- nocopd.race.table$Var1
nocopd.race.table$Var1 <- NULL
race.table <- cbind(copd.race.table, nocopd.race.table)
race.table <- race.table[c(6, 2, 1, 5, 3, 4),]
colnames(race.table) <- c("COPD", "NO COPD")
race.table$`p-value` <- c(signif(chisq.test(race.table)$p.value, 3),
rep("", nrow(race.table) - 1))
blank <- as.data.frame(matrix("", ncol = 3))
colnames(blank) <- c("COPD", "NO COPD", "p-value")
rownames(blank) <- "Race"
race.table <- rbind(blank,race.table)
demo.table <- rbind(demo.table, race.table)
demo.table %>%
knitr::kable(
format = "html", align = rep("c", ncol(demo.table) + 1),
row.names = TRUE
) %>%
add_indent(c(8:13)) %>%
kableExtra::kable_styling()
| COPD | NO COPD | p-value | |
|---|---|---|---|
| Age | 63.4 +/- 5.72 | 63.3 +/- 6.6 | 0.804 |
| Gender | Male: 71(78%) | Male: 67(83.8%) | 0.452 |
| FEV1 Predicted(%) | 60.5 +/- 12.4 | 86.5 +/- 13.5 | 1.37e-22 |
| FEV1/FVC | 0.563 +/- 0.1 | 0.717 +/- 0.067 | 2.04e-21 |
| TIN | 70.5 +/- 1.23 | 70.4 +/- 1.44 | 0.903 |
| Smoking Status | Current: 34(37.4%) | Current: 28(35%) | 0.872 |
| Race | |||
| White | 69 | 61 | 0.518 |
| Black or African American | 17 | 11 | |
| Asian | 2 | 2 | |
| Pacific Islander | 2 | 1 | |
| Native American | 0 | 1 | |
| Not Reported | 1 | 4 |
Differential expression was conducted using the DESeq2 package to compare patients with low FEV1pred values (< 80) and high values. The FEV1 predicted values are used as a proxy for COPD status. Expected counts outputted from the RSEM algorithm was taken for DESeq2.
Model used: ~Smoking status + Age + TIN + FEV1 predicted
dds <- DESeqDataSetFromMatrix(
countData = counts,
colData = annotBronch,
design = ~GRPB_SMK_STS + AGE + TIN + FEV_RS_PER
)
dds$GRPB_SMK_STS <- relevel(dds$GRPB_SMK_STS, ref = "Former_Smoker")
keep <- rowSums(counts(dds)) >= 10
dds <- dds[keep, ]
dds <- DESeq(dds)
res <- results(dds)
res$nLogPVal <- -log10(res$padj)
resOrdered <- res[order(res$pvalue), ]
resOrdered <- as.data.frame(resOrdered)
#For pre-ranked GSEA
resOrderLFC <- res[order(res$log2FoldChange), ]
resOrderLFC <- resOrderLFC[,2, drop = F]
resOrderLFC$Gene <- rownames(resOrderLFC)
resOrderLFC <- resOrderLFC[,c(2,1)]
#write.table(resOrderLFC, "20201104_GSEA_Rankedlist_FEVPred_Bronch.rnk", sep = "\t", col.names = T, row.names = F)
resSig <- resOrdered[resOrdered$padj < 0.05,]
resSig <- resSig[!is.na(resSig$padj),]
resSig <- resSig[order(resSig$log2FoldChange), ]
numSig <- nrow(resSig)
resSigUp <- resSig[head(order(resSig$log2FoldChange, decreasing = T), 50),]
resSigDown <- resSig[head(order(resSig$log2FoldChange, decreasing = F), 50),]
resSig2 <- rbind(resSigDown, resSigUp)
# numUp <- nrow(resSig[resSig$log2FoldChange > 0.5, ])
# numDown <- nrow(resSig[resSig$log2FoldChange < -0.5, ])
resSig3 <- resSig[abs(resSig$log2FoldChange) > 0.01,]
A total of 1234 genes were passed the adjusted p-value < 0.05 threshold.
g <- ggplot(resOrdered, aes(x = log2FoldChange, y = nLogPVal)) +
geom_point(size = 0.75) +
ggplot2::theme_bw() +
ggplot2::theme(
panel.grid.major = ggplot2::element_blank(),
panel.grid.minor = ggplot2::element_blank(),
axis.text = ggplot2::element_text(size = 14),
axis.title = ggplot2::element_text(size = 14)
) +
ggplot2::theme(legend.title = ggplot2::element_text(size = 15), legend.text = ggplot2::element_text(size = 13)) +
ggplot2::guides(
colour =
ggplot2::guide_legend(override.aes = list(size = 2))
)
if(nrow(resSig2) > 0){
g <- g +
geom_point(data = resSig2, aes(x = log2FoldChange, y = nLogPVal), color = "Red")+
ggplot2::labs(y = "-log10(Adjusted p-value)") +
ggplot2::ggtitle(label = "COPD status") +
ggplot2::theme(plot.title = ggplot2::element_text(
hjust = 0.5,
size = 18
)) + geom_line(y = 1.3)
}
g
The red dots show the top 50 most up/down regulated genes which pass the adjusted p-value threshold.
counts.z <- t(scale(t(counts)))
counts.z.trim <- counts.z
counts.z.trim[counts.z.trim < -2] <- -2
counts.z.trim[counts.z.trim > 2] <- 2
counts.z.trim <- counts.z.trim[rownames(counts.z.trim) %in% rownames(resSig),]
COPD_status <- annotBronch$COPD_status
Smoker_status <- annotBronch$GRPB_SMK_STS
annotation_col <- data.frame(COPD_status, Smoker_status)
rownames(annotation_col) <- colnames(counts.z.trim)
callback <- function(hc, mat) {
sv <- svd(t(mat))$v[, 1]
dend <- reorder(as.dendrogram(hc), wts = sv)
as.hclust(dend)
}
out <- pheatmap(counts.z.trim,
color = colorRampPalette(rev(brewer.pal(n = 7, name = "RdYlBu")))(100),
annotation_col = annotation_col,
legend = T,
show_rownames = F,
show_colnames = F,
fontsize_row = 9,
cluster_rows = TRUE,
cluster_cols = TRUE
)
out
474 genes total:
counts.z <- t(scale(t(counts)))
counts.z.trim <- counts.z
counts.z.trim[counts.z.trim < -2] <- -2
counts.z.trim[counts.z.trim > 2] <- 2
counts.z.trim <- counts.z.trim[rownames(counts.z.trim) %in% rownames(resSig3),]
COPD_status <- annotBronch$COPD_status
Smoker_status <- annotBronch$GRPB_SMK_STS
annotation_col <- data.frame(COPD_status, Smoker_status)
rownames(annotation_col) <- colnames(counts.z.trim)
callback <- function(hc, mat) {
sv <- svd(t(mat))$v[, 1]
dend <- reorder(as.dendrogram(hc), wts = sv)
as.hclust(dend)
}
out <- pheatmap(counts.z.trim,
color = colorRampPalette(rev(brewer.pal(n = 7, name = "RdYlBu")))(100),
annotation_col = annotation_col,
legend = T,
show_rownames = F,
show_colnames = F,
fontsize_row = 9,
cluster_rows = TRUE,
cluster_cols = TRUE
)
out
counts.z <- t(scale(t(counts)))
counts.z.trim <- counts.z
counts.z.trim[counts.z.trim < -2] <- -2
counts.z.trim[counts.z.trim > 2] <- 2
counts.z.trim <- counts.z.trim[rownames(counts.z.trim) %in% rownames(resSig2),]
COPD_status <- annotBronch$COPD_status
Smoker_status <- annotBronch$GRPB_SMK_STS
annotation_col <- data.frame(COPD_status, Smoker_status)
rownames(annotation_col) <- colnames(counts.z.trim)
callback <- function(hc, mat) {
sv <- svd(t(mat))$v[, 1]
dend <- reorder(as.dendrogram(hc), wts = sv)
as.hclust(dend)
}
out <- pheatmap(counts.z.trim,
color = colorRampPalette(rev(brewer.pal(n = 7, name = "RdYlBu")))(100),
annotation_col = annotation_col,
legend = T,
show_rownames = F,
show_colnames = F,
fontsize_row = 9,
cluster_rows = TRUE,
cluster_cols = TRUE
)
out
resSigUp <- resSig[head(order(resSig$log2FoldChange, decreasing = T), 50),]
resSigUp <- resSigUp[,c(2,5,6)]
colnames(resSigUp) <- c("Log2FC", "P-value", "Adj. P-value")
resSigUp %>%
knitr::kable(
format = "html", align = rep("c", ncol(resSig) + 1),
row.names = TRUE
) %>%
kableExtra::kable_styling() %>%
kableExtra::scroll_box(height = "300px")
| Log2FC | P-value | Adj. P-value | |
|---|---|---|---|
| PRSS27 | 0.0379322 | 0.0000002 | 0.0002730 |
| COL4A3 | 0.0365198 | 0.0000034 | 0.0016830 |
| WSCD2 | 0.0289860 | 0.0005595 | 0.0230708 |
| HOPX | 0.0273427 | 0.0000001 | 0.0001944 |
| ANXA9 | 0.0269131 | 0.0000076 | 0.0023858 |
| TRBV20-1 | 0.0267765 | 0.0002577 | 0.0153139 |
| GPM6A | 0.0267225 | 0.0001038 | 0.0095784 |
| KRT4 | 0.0253379 | 0.0000648 | 0.0074744 |
| LGI3 | 0.0250411 | 0.0001393 | 0.0109865 |
| SFTPD | 0.0249287 | 0.0000008 | 0.0007153 |
| VGLL1 | 0.0249255 | 0.0005055 | 0.0218765 |
| SOGA3 | 0.0242900 | 0.0005414 | 0.0228082 |
| LRCH2 | 0.0241826 | 0.0002670 | 0.0156622 |
| LYPD2 | 0.0241066 | 0.0002184 | 0.0140391 |
| RP11-493K19.3 | 0.0237056 | 0.0000286 | 0.0049170 |
| CYP4F22 | 0.0234669 | 0.0017149 | 0.0410806 |
| WNK4 | 0.0233429 | 0.0009922 | 0.0312846 |
| GCOM1 | 0.0229288 | 0.0000214 | 0.0040991 |
| KCNAB1 | 0.0226309 | 0.0018498 | 0.0423868 |
| CCR6 | 0.0223424 | 0.0014622 | 0.0378144 |
| COL11A2 | 0.0215869 | 0.0004802 | 0.0211319 |
| SCUBE1 | 0.0214229 | 0.0000167 | 0.0035708 |
| GPR25 | 0.0211229 | 0.0011971 | 0.0341430 |
| RP1-214M20.2 | 0.0211051 | 0.0002003 | 0.0134020 |
| GRIK1 | 0.0208795 | 0.0001860 | 0.0128619 |
| KLRC3 | 0.0206905 | 0.0004250 | 0.0199691 |
| CNFN | 0.0206484 | 0.0002364 | 0.0146705 |
| FRMPD4 | 0.0205462 | 0.0004602 | 0.0206864 |
| MC4R | 0.0202437 | 0.0017792 | 0.0417944 |
| GABBR2 | 0.0201894 | 0.0001731 | 0.0121874 |
| TGM3 | 0.0198160 | 0.0000482 | 0.0062098 |
| TTN | 0.0195382 | 0.0001459 | 0.0112596 |
| ABCG2 | 0.0193495 | 0.0004597 | 0.0206864 |
| TRGV9 | 0.0192770 | 0.0008214 | 0.0278741 |
| LINC01140 | 0.0189824 | 0.0000563 | 0.0069139 |
| RP1-302D9.3 | 0.0188891 | 0.0011866 | 0.0340451 |
| NDRG4 | 0.0186677 | 0.0000000 | 0.0000894 |
| DMRT1 | 0.0184242 | 0.0014015 | 0.0372039 |
| CLCA4 | 0.0182427 | 0.0006618 | 0.0250146 |
| PNMAL1 | 0.0182427 | 0.0000489 | 0.0062591 |
| IL23R | 0.0182318 | 0.0010009 | 0.0313901 |
| ISLR | 0.0179292 | 0.0000413 | 0.0057640 |
| TRGC1 | 0.0177230 | 0.0002066 | 0.0136422 |
| LYPD1 | 0.0176844 | 0.0001246 | 0.0103622 |
| HTR2B | 0.0176811 | 0.0001100 | 0.0097128 |
| RP4-635E18.6 | 0.0176241 | 0.0001005 | 0.0095321 |
| CTSW | 0.0176167 | 0.0012864 | 0.0356947 |
| JAM2 | 0.0174415 | 0.0026048 | 0.0499456 |
| SVOP | 0.0170479 | 0.0023990 | 0.0474275 |
| EEF1A1P13 | 0.0169299 | 0.0000057 | 0.0019819 |
resSigDown <- resSig[head(order(resSig$log2FoldChange, decreasing = F), 50),]
resSigDown <- resSigDown[,c(2,5,6)]
colnames(resSigDown) <- c("Log2FC", "P-value", "Adj. P-value")
resSigDown %>%
knitr::kable(
format = "html", align = rep("c", ncol(resSig) + 1),
row.names = TRUE
) %>%
kableExtra::kable_styling() %>%
kableExtra::scroll_box(height = "300px")
| Log2FC | P-value | Adj. P-value | |
|---|---|---|---|
| BPIFB6 | -0.0484129 | 0.0000008 | 0.0007153 |
| Z82214.3 | -0.0475271 | 0.0000042 | 0.0017656 |
| APOB | -0.0452260 | 0.0000000 | 0.0000520 |
| MUC6 | -0.0375644 | 0.0000454 | 0.0060877 |
| SLC13A5 | -0.0362348 | 0.0000002 | 0.0003003 |
| BPIFB2 | -0.0360447 | 0.0000040 | 0.0017584 |
| GAPDHP24 | -0.0357892 | 0.0000656 | 0.0074744 |
| TPO | -0.0346712 | 0.0000002 | 0.0002730 |
| CDH15 | -0.0340649 | 0.0000050 | 0.0019048 |
| ARHGAP40 | -0.0339831 | 0.0000001 | 0.0002175 |
| ADAMTS2 | -0.0331682 | 0.0002798 | 0.0160567 |
| REG4 | -0.0330795 | 0.0001281 | 0.0104900 |
| CACNA1E | -0.0317633 | 0.0000000 | 0.0000148 |
| CREG2 | -0.0313896 | 0.0005600 | 0.0230708 |
| U3.80 | -0.0312975 | 0.0001503 | 0.0113298 |
| PIRT | -0.0310768 | 0.0014278 | 0.0373721 |
| RP11-481N16.1 | -0.0307317 | 0.0005510 | 0.0229493 |
| CYP17A1 | -0.0307271 | 0.0002142 | 0.0138803 |
| AKR1B15 | -0.0307221 | 0.0018493 | 0.0423868 |
| PTHLH | -0.0304859 | 0.0000000 | 0.0000894 |
| RP11-157E16.1 | -0.0304788 | 0.0002690 | 0.0157058 |
| RP11-16E12.2 | -0.0300302 | 0.0000032 | 0.0016404 |
| SEMA6B | -0.0297027 | 0.0000248 | 0.0046511 |
| IL19 | -0.0293362 | 0.0000041 | 0.0017584 |
| CHRM1 | -0.0291805 | 0.0003002 | 0.0164826 |
| ZDHHC4P1 | -0.0289177 | 0.0000001 | 0.0001944 |
| CCL2 | -0.0284188 | 0.0016311 | 0.0402878 |
| RP11-167N4.2 | -0.0282905 | 0.0000959 | 0.0093885 |
| SLC25A48 | -0.0276517 | 0.0001416 | 0.0110567 |
| ALOX15B | -0.0271650 | 0.0006381 | 0.0246279 |
| ANO7 | -0.0265786 | 0.0000001 | 0.0002251 |
| IL17REL | -0.0265489 | 0.0000328 | 0.0050852 |
| CUX2 | -0.0260713 | 0.0000006 | 0.0006226 |
| AL133373.1 | -0.0259011 | 0.0000002 | 0.0003003 |
| FBN2 | -0.0256705 | 0.0000000 | 0.0000145 |
| RP11-395B7.2 | -0.0256592 | 0.0000197 | 0.0039108 |
| CTD-2530H12.7 | -0.0248494 | 0.0000021 | 0.0014090 |
| STXBP5L | -0.0245286 | 0.0008426 | 0.0282699 |
| NTRK2 | -0.0244881 | 0.0000192 | 0.0038664 |
| LINC00632 | -0.0235877 | 0.0000469 | 0.0061483 |
| DUSP5P1 | -0.0235702 | 0.0000309 | 0.0049938 |
| SNTG2 | -0.0235254 | 0.0000199 | 0.0039108 |
| CCL24 | -0.0235165 | 0.0016407 | 0.0403513 |
| RP11-115D19.1 | -0.0234537 | 0.0009154 | 0.0299849 |
| ZNF467 | -0.0233902 | 0.0000002 | 0.0003003 |
| AZGP1 | -0.0233431 | 0.0000005 | 0.0005460 |
| RPS20P1 | -0.0232315 | 0.0000031 | 0.0016404 |
| BCAS2P2 | -0.0231343 | 0.0000151 | 0.0034200 |
| ASB11 | -0.0228571 | 0.0005534 | 0.0229795 |
| B3GNT6 | -0.0228472 | 0.0008057 | 0.0276069 |
Differential expression was conducted using the DESeq2 package to compare patients with low FEV1pred values (< 80) and high values, where all samples with low FEV1pred is considered to be COPD. Expected counts outputted from the RSEM algorithm was taken for DESeq2.
Model used: ~Smoking status + Age + TIN + COPD status
dds <- DESeqDataSetFromMatrix(
countData = counts,
colData = annotBronch,
design = ~GRPB_SMK_STS + AGE + TIN + COPD_status
)
dds$GRPB_SMK_STS <- relevel(dds$GRPB_SMK_STS, ref = "Former_Smoker")
dds$COPD_status <- relevel(dds$COPD_status, ref = "NO_COPD")
keep <- rowSums(counts(dds)) >= 10
dds <- dds[keep, ]
dds <- DESeq(dds)
res <- results(dds)
res$nLogPVal <- -log10(res$padj)
resOrdered <- res[order(res$pvalue), ]
resOrdered <- as.data.frame(resOrdered)
#For pre-ranked GSEA
resOrderLFC <- res[order(res$log2FoldChange, decreasing = FALSE), ]
resOrderLFC <- resOrderLFC[,2, drop = F]
resOrderLFC$SAMPLE <- rownames(resOrderLFC)
resOrderLFC <- resOrderLFC[,c(2,1)]
write.table(resOrderLFC, "20201104_GSEA_Rankedlist_COPDstatus_Bronch.rnk", sep = "\t", col.names = T, row.names = F)
resSig <- resOrdered %>%
filter(padj < 0.05) %>%
filter(abs(log2FoldChange) > 0.5)
numSig <- nrow(resSig)
numUp <- nrow(resSig[resSig$log2FoldChange > 0.5, ])
numDown <- nrow(resSig[resSig$log2FoldChange < -0.5, ])
A total of 619(419 Upregulated, 200 Downregulated) genes were differentially expressed (padj < 0.05, abs(log2FC) > 0.5).
# steilingMicroarray <- readRDS("/restricted/projectnb/camplab/home/ykoga07/DECAMP/Novartis/Data/STEILING_bronch.RDS")
#
# arrayPheno <- Biobase::pData(steilingMicroarray)
# arrayPheno$fev1_fvc_ratio <- arrayPheno$fev1_fvc_ratio/100
#
# design <- model.matrix(~smoking_status+age+copd, data = arrayPheno)
# # design <- model.matrix(~percent_fev1+fev1_fvc_ratio+smoking_status+age+copd, data = arrayPheno)
# # design <- model.matrix(~percent_fev1+fev1_fvc_ratio+smoking_status+age+copd, data = arrayPheno)
#
# fit <- lmFit(steilingMicroarray, design) # fit each probeset to model
# efit <- eBayes(fit) # empirical Bayes adjustment
# de.res <- topTable(efit, coef=2, number = 100000)
#
# de.res$GeneName <- gsub("_at","",rownames(de.res))
# de.res$nLogPVal <- -log(de.res$adj.P.Val)
# eset.ranklist <- de.res[,c(9,3)]
# eset.ranklist <- eset.ranklist[order(eset.ranklist$logFC, decreasing = FALSE),]
# eset.ranklist <- read.table("/restricted/projectnb/camplab/home/ykoga07/DECAMP/Novartis/Analysis/1stPass/100525_lam_copdcovars_tval.rnk", header = F)
#
# mart <- useMart(biomart = "ensembl", dataset = "hsapiens_gene_ensembl")
#
# BM <- getBM(filters= "hgnc_symbol", attributes= c("ensembl_gene_id","hgnc_symbol"),values=eset.ranklist$V1,mart= mart)
#
# BM <- BM[BM$ensembl_gene_id %in% rownames(assay(seBronch)),]
# BM <- BM[!duplicated(BM$hgnc_symbol),]
# mergeBM <- merge(eset.ranklist, BM, by.x = "V1", by.y = "hgnc_symbol")
# mergeBM <- mergeBM[,c(3,2)]
# mergeBM <- mergeBM[order(mergeBM$V2, decreasing = F),]
# mergeBM <- mergeBM[!duplicated(mergeBM$ensembl_gene_id),]
#
# resSig2 <- resSig[rownames(resSig) %in% mergeBM$ensembl_gene_id,]
# resSig2Up <- resSig2[resSig2$log2FoldChange>0.5,]
# resSig2Down <- resSig2[resSig2$log2FoldChange < -0.5,]
# write.table(x = rownames(resSig2Up), file = "/restricted/projectnb/camplab/home/ykoga07/DECAMP/Novartis/Analysis/1stPass/20201125_DECAMP_Bronch_geneList_Up.grp", col.names = F, row.names = F)
# write.table(x = rownames(resSig2Down), file = "/restricted/projectnb/camplab/home/ykoga07/DECAMP/Novartis/Analysis/1stPass/20201125_DECAMP_Bronch_geneList_Down.grp", col.names = F, row.names = F)
# write.table(mergeBM, "20201125_GSEA_Rankedlist_COPDstatus_Bronch_FromSteilingMicroarray.rnk", sep = "\t", col.names = F, row.names = F)
ggplot(resOrdered, aes(x = log2FoldChange, y = nLogPVal)) +
geom_point(size = 0.75) +
ggplot2::theme_bw() +
ggplot2::theme(
panel.grid.major = ggplot2::element_blank(),
panel.grid.minor = ggplot2::element_blank(),
axis.text = ggplot2::element_text(size = 14),
axis.title = ggplot2::element_text(size = 14)
) +
ggplot2::theme(legend.title = ggplot2::element_text(size = 15), legend.text = ggplot2::element_text(size = 13)) +
ggplot2::guides(
colour =
ggplot2::guide_legend(override.aes = list(size = 2))
) +
geom_point(data = resSig, aes(x = log2FoldChange, y = nLogPVal), color = "Red")+
ggplot2::labs(y = "-log10(Adjusted p-value)") +
ggplot2::ggtitle(label = "COPD status") +
ggplot2::theme(plot.title = ggplot2::element_text(
hjust = 0.5,
size = 18
))
counts.z <- t(scale(t(counts)))
counts.z.trim <- counts.z
counts.z.trim[counts.z.trim < -2] <- -2
counts.z.trim[counts.z.trim > 2] <- 2
counts.z.trim <- counts.z.trim[rownames(counts.z.trim) %in% rownames(resSig),]
COPD_status <- annotBronch$COPD_status
Smoker_status <- annotBronch$GRPB_SMK_STS
annotation_col <- data.frame(COPD_status, Smoker_status)
rownames(annotation_col) <- colnames(counts.z.trim)
callback <- function(hc, mat) {
sv <- svd(t(mat))$v[, 1]
dend <- reorder(as.dendrogram(hc), wts = sv)
as.hclust(dend)
}
out <- pheatmap(counts.z.trim,
color = colorRampPalette(rev(brewer.pal(n = 7, name = "RdYlBu")))(100),
annotation_col = annotation_col,
legend = T,
show_rownames = F,
show_colnames = F,
fontsize_row = 9,
cluster_rows = TRUE,
cluster_cols = TRUE
)
out
dots <- T
boxplot <- F
violin <- T
df <- data.frame(
x = annotBronch$`Sample Type`,
y = counts["CEACAM5",]
)
p <- ggplot2::ggplot(df) +
ggplot2::aes_string(
x = "x",
y = "y"
)
if (dots == TRUE) {
p <- p + ggplot2::geom_jitter(
color = "blue",
width = 0.2,
height = 0,
size = 1,
alpha = 1
)
}
if (boxplot == TRUE) {
p <- p + ggplot2::geom_boxplot(
width = 0.5,
alpha = 0
)
}
if (violin == TRUE) {
p <- p + ggplot2::geom_violin(
trim = TRUE,
scale = "width",
size = 1,
fill = "grey",
alpha = 0.75
)
}
p <- p + ggplot2::theme_bw() +
ggplot2::theme(
panel.grid.major = ggplot2::element_blank(),
panel.grid.minor = ggplot2::element_blank(),
axis.text = ggplot2::element_text(size = 14),
axis.title = ggplot2::element_text(size = 10)
) + ggplot2::theme(axis.text.x = ggplot2::element_text(size = 15)) +
ggplot2::ylab("Counts") +
ggplot2::theme(
axis.title.y = element_text(size = 15),
axis.title.x = ggplot2::element_blank()
)
p <- p + ggplot2::ggtitle(label = "Gene: CEACAM5") +
ggplot2::theme(plot.title = ggplot2::element_text(
hjust = 0.5,
size = 18
))
p
resSigDown <- resSig[resSig$log2FoldChange < -0.5, ]
resSigDown <- resSigDown[order(resSigDown$log2FoldChange, decreasing = F),]
resSigDown <- resSigDown[,c(2,5,6)]
colnames(resSigDown) <- c("Log2FC", "P-value", "Adj. P-value")
resSigDown %>%
knitr::kable(
format = "html", align = rep("c", ncol(resSig) + 1),
row.names = TRUE
) %>%
kableExtra::kable_styling() %>%
kableExtra::scroll_box(height = "300px")
| Log2FC | P-value | Adj. P-value | |
|---|---|---|---|
| HCG22 | -2.3864692 | 0.0015128 | 0.0201796 |
| SLURP1 | -1.7935469 | 0.0003667 | 0.0086078 |
| TRBV4-2 | -1.7882811 | 0.0000122 | 0.0011873 |
| IGHG4 | -1.6651710 | 0.0014029 | 0.0193048 |
| PRSS27 | -1.6101254 | 0.0000000 | 0.0000010 |
| OPN1SW | -1.5957304 | 0.0010852 | 0.0166257 |
| FENDRR | -1.3582936 | 0.0005712 | 0.0111520 |
| HOPX | -1.2004463 | 0.0000000 | 0.0000003 |
| ANXA9 | -1.1863015 | 0.0000000 | 0.0000225 |
| SOGA3 | -1.1492763 | 0.0000050 | 0.0007196 |
| RP11-64C1.1 | -1.1236122 | 0.0002747 | 0.0073143 |
| TRAV4 | -1.1165131 | 0.0006128 | 0.0116053 |
| DOK5 | -1.0939985 | 0.0000523 | 0.0028516 |
| TMEM145 | -1.0712583 | 0.0002076 | 0.0062665 |
| ZNF728 | -1.0521973 | 0.0043615 | 0.0382570 |
| KISS1 | -1.0231259 | 0.0000045 | 0.0006861 |
| CNFN | -1.0093486 | 0.0000004 | 0.0001590 |
| TRAV21 | -1.0008325 | 0.0011965 | 0.0176970 |
| TGM3 | -0.9997551 | 0.0000000 | 0.0000090 |
| ABCG2 | -0.9948421 | 0.0000004 | 0.0001513 |
| RP11-250H24.4 | -0.9759165 | 0.0024518 | 0.0268393 |
| DIRAS2 | -0.9724012 | 0.0000026 | 0.0005001 |
| WSCD2 | -0.9716562 | 0.0015092 | 0.0201796 |
| SLC4A10 | -0.9445816 | 0.0003535 | 0.0084306 |
| CYP4F22 | -0.9350872 | 0.0005134 | 0.0105094 |
| GABRD | -0.9303349 | 0.0008577 | 0.0144304 |
| PCOLCE2 | -0.9291663 | 0.0030267 | 0.0304347 |
| RP11-377G16.2 | -0.9270751 | 0.0020774 | 0.0243381 |
| GCOM1 | -0.9066369 | 0.0000031 | 0.0005595 |
| ALOX12 | -0.8962265 | 0.0000466 | 0.0026593 |
| RP1-214M20.2 | -0.8847713 | 0.0000144 | 0.0012903 |
| TM4SF19.1 | -0.8822887 | 0.0060362 | 0.0462842 |
| SFTPD | -0.8781367 | 0.0000018 | 0.0003930 |
| SPARCL1 | -0.8767599 | 0.0000007 | 0.0002323 |
| RP11-875H7.5 | -0.8634227 | 0.0009141 | 0.0149692 |
| GPM6A | -0.8609836 | 0.0006162 | 0.0116407 |
| TRGV4 | -0.8596803 | 0.0017601 | 0.0219497 |
| TRBV20-1 | -0.8572522 | 0.0013399 | 0.0187906 |
| FABP3 | -0.8390524 | 0.0065172 | 0.0485614 |
| LRCH2 | -0.8287418 | 0.0005165 | 0.0105484 |
| RP11-493K19.3 | -0.8224368 | 0.0000654 | 0.0032312 |
| LYPD1 | -0.8221815 | 0.0000005 | 0.0001722 |
| GRIK1 | -0.8071296 | 0.0000590 | 0.0030600 |
| OR51E2 | -0.8057666 | 0.0007976 | 0.0136894 |
| GRID1 | -0.8056541 | 0.0000616 | 0.0031605 |
| HHIP | -0.7990500 | 0.0000452 | 0.0026455 |
| C21orf88 | -0.7950731 | 0.0017756 | 0.0220915 |
| CTD-2626G11.2 | -0.7946462 | 0.0000249 | 0.0017812 |
| HLA-DQB2 | -0.7889908 | 0.0002631 | 0.0071085 |
| A2ML1 | -0.7834005 | 0.0044364 | 0.0386373 |
| CYS1 | -0.7766507 | 0.0000205 | 0.0015617 |
| ZNF835 | -0.7660486 | 0.0003671 | 0.0086078 |
| RP1-302D9.3 | -0.7657790 | 0.0002659 | 0.0071756 |
| RP11-215H22.1 | -0.7632948 | 0.0002108 | 0.0062863 |
| KIF12 | -0.7590129 | 0.0006999 | 0.0125690 |
| MC4R | -0.7565352 | 0.0012489 | 0.0181279 |
| CRTAM | -0.7532744 | 0.0001553 | 0.0053904 |
| ZNF385B | -0.7483271 | 0.0022363 | 0.0253666 |
| FLT4 | -0.7464879 | 0.0052498 | 0.0425079 |
| AC002456.2 | -0.7454221 | 0.0008882 | 0.0147313 |
| GPC3 | -0.7431350 | 0.0000008 | 0.0002460 |
| GABBR2 | -0.7405785 | 0.0001379 | 0.0050188 |
| TMPRSS11A | -0.7390167 | 0.0051653 | 0.0422233 |
| TBX4 | -0.7351109 | 0.0006565 | 0.0120741 |
| SCGB3A1 | -0.7348552 | 0.0005690 | 0.0111492 |
| SCGB1A1 | -0.7342287 | 0.0056071 | 0.0442569 |
| TMPRSS11E | -0.7332024 | 0.0006886 | 0.0124607 |
| CTXN3 | -0.7328341 | 0.0041174 | 0.0368094 |
| TMPRSS11F | -0.7327097 | 0.0067088 | 0.0493200 |
| RP11-73M7.6 | -0.7302310 | 0.0025263 | 0.0272698 |
| KCNJ1 | -0.7226517 | 0.0008292 | 0.0140521 |
| CAMK2N1 | -0.7168096 | 0.0000114 | 0.0011414 |
| CD52 | -0.7147869 | 0.0009119 | 0.0149692 |
| ISLR | -0.7081926 | 0.0000080 | 0.0009471 |
| NPPC | -0.7066265 | 0.0000816 | 0.0036453 |
| SLC6A13 | -0.7023833 | 0.0002920 | 0.0076297 |
| MFAP4 | -0.6926880 | 0.0014551 | 0.0197597 |
| SLC5A7 | -0.6912281 | 0.0001584 | 0.0054604 |
| C2orf72 | -0.6864001 | 0.0037487 | 0.0347841 |
| RPL32P1 | -0.6757923 | 0.0021953 | 0.0250980 |
| KRT4 | -0.6741877 | 0.0040932 | 0.0367187 |
| JAM2 | -0.6728379 | 0.0012574 | 0.0182066 |
| SCUBE1 | -0.6722157 | 0.0002405 | 0.0068286 |
| CTSW | -0.6650400 | 0.0008849 | 0.0147150 |
| STAC | -0.6637347 | 0.0012836 | 0.0183927 |
| AC068831.3 | -0.6612633 | 0.0040383 | 0.0363660 |
| BPI | -0.6593759 | 0.0002061 | 0.0062665 |
| DUSP26 | -0.6587218 | 0.0002169 | 0.0063910 |
| EMP1 | -0.6578094 | 0.0007782 | 0.0135407 |
| FEZF2 | -0.6554235 | 0.0029164 | 0.0297500 |
| C6orf229 | -0.6545682 | 0.0061458 | 0.0467481 |
| PLA2G1B | -0.6545144 | 0.0028344 | 0.0292210 |
| CLEC4F | -0.6535467 | 0.0003011 | 0.0077735 |
| ACOXL | -0.6446535 | 0.0000925 | 0.0039035 |
| KCNA3 | -0.6443652 | 0.0002871 | 0.0075340 |
| RP11-307C19.1 | -0.6438555 | 0.0035422 | 0.0335697 |
| ST6GAL2 | -0.6418108 | 0.0000024 | 0.0004794 |
| RP4-785G19.5 | -0.6416908 | 0.0021960 | 0.0250980 |
| CTC-260E6.6 | -0.6414205 | 0.0013201 | 0.0186358 |
| TRAC | -0.6399490 | 0.0001824 | 0.0059236 |
| P4HA3 | -0.6391167 | 0.0001123 | 0.0044235 |
| EEF1A1P13 | -0.6388126 | 0.0000029 | 0.0005433 |
| MEIOB | -0.6382258 | 0.0046355 | 0.0396591 |
| MYZAP | -0.6282005 | 0.0022378 | 0.0253718 |
| CLCA4 | -0.6257042 | 0.0014691 | 0.0198866 |
| ADAMTSL1 | -0.6256839 | 0.0000280 | 0.0019072 |
| GPR174 | -0.6240299 | 0.0001287 | 0.0048256 |
| JAKMIP2 | -0.6153699 | 0.0004362 | 0.0095129 |
| DLC1 | -0.6152811 | 0.0024294 | 0.0267082 |
| SMTNL2 | -0.6109394 | 0.0022274 | 0.0253102 |
| DMRT1 | -0.6096933 | 0.0034794 | 0.0331327 |
| CYP2W1 | -0.6084916 | 0.0004378 | 0.0095225 |
| SYT13 | -0.6082086 | 0.0001410 | 0.0050749 |
| GPR124 | -0.6075574 | 0.0005623 | 0.0110796 |
| RP11-284N8.3 | -0.6071607 | 0.0007323 | 0.0129842 |
| RP11-239E10.2 | -0.6071463 | 0.0000102 | 0.0010914 |
| SLC7A14 | -0.6069894 | 0.0033177 | 0.0321168 |
| BEX1 | -0.6049220 | 0.0006089 | 0.0115753 |
| TSPAN18 | -0.6046893 | 0.0037386 | 0.0347536 |
| CPB2-AS1 | -0.5960951 | 0.0022490 | 0.0254654 |
| CD207 | -0.5914865 | 0.0007423 | 0.0130941 |
| LEPR | -0.5863591 | 0.0009848 | 0.0156428 |
| KCNJ6 | -0.5856257 | 0.0003463 | 0.0083552 |
| FCRL6 | -0.5850643 | 0.0061356 | 0.0467069 |
| KCNK3 | -0.5835709 | 0.0004749 | 0.0100396 |
| CX3CR1 | -0.5829135 | 0.0007260 | 0.0128821 |
| FRRS1L | -0.5827754 | 0.0047766 | 0.0403116 |
| KRT17P2 | -0.5813198 | 0.0041036 | 0.0367523 |
| ADH1B | -0.5805016 | 0.0000050 | 0.0007196 |
| ITM2A | -0.5803643 | 0.0001585 | 0.0054604 |
| ZNF114 | -0.5789884 | 0.0008611 | 0.0144786 |
| CDH7 | -0.5785158 | 0.0021593 | 0.0248669 |
| RAMP2 | -0.5784359 | 0.0000124 | 0.0011976 |
| KIAA0408 | -0.5783474 | 0.0008939 | 0.0147609 |
| AC007347.1 | -0.5748353 | 0.0001597 | 0.0054860 |
| CCL5 | -0.5740615 | 0.0016482 | 0.0212110 |
| NPBWR1 | -0.5722081 | 0.0042003 | 0.0372118 |
| RP4-635E18.6 | -0.5721799 | 0.0005734 | 0.0111693 |
| PEG10 | -0.5712589 | 0.0000176 | 0.0014563 |
| CNGA1 | -0.5691645 | 0.0002345 | 0.0067324 |
| TRGC2 | -0.5684042 | 0.0020908 | 0.0244379 |
| DDC | -0.5649902 | 0.0008754 | 0.0146235 |
| SKAP1 | -0.5636253 | 0.0000010 | 0.0002639 |
| SEC14L3 | -0.5633833 | 0.0046436 | 0.0396887 |
| PPFIA2 | -0.5622687 | 0.0005713 | 0.0111520 |
| NDRG4 | -0.5620810 | 0.0000066 | 0.0008342 |
| QPRT | -0.5580279 | 0.0000128 | 0.0012152 |
| TSPAN7 | -0.5579895 | 0.0002001 | 0.0061642 |
| HLA-DOA | -0.5576637 | 0.0043708 | 0.0382805 |
| APOBEC3H | -0.5544878 | 0.0002150 | 0.0063758 |
| AC020571.3 | -0.5543959 | 0.0048194 | 0.0405436 |
| UBE2QL1 | -0.5516127 | 0.0000493 | 0.0027462 |
| MYOZ1 | -0.5512993 | 0.0001388 | 0.0050445 |
| RUNX1T1 | -0.5498136 | 0.0001105 | 0.0043950 |
| LINC01140 | -0.5451518 | 0.0017522 | 0.0219488 |
| IFIT1 | -0.5442635 | 0.0000943 | 0.0039184 |
| CSTF3-AS1 | -0.5435079 | 0.0002272 | 0.0065993 |
| PADI3 | -0.5398219 | 0.0015904 | 0.0207453 |
| LGR5 | -0.5377769 | 0.0044125 | 0.0385223 |
| CH25H | -0.5372711 | 0.0000388 | 0.0024265 |
| AP001347.6 | -0.5361103 | 0.0002610 | 0.0070739 |
| OASL | -0.5355939 | 0.0056885 | 0.0447076 |
| SNCG | -0.5345337 | 0.0001499 | 0.0052986 |
| CTD-2135D7.2 | -0.5325317 | 0.0049373 | 0.0411311 |
| ROBO2 | -0.5306888 | 0.0000302 | 0.0020068 |
| ADH1C | -0.5276992 | 0.0000063 | 0.0008142 |
| RP11-389K14.3 | -0.5272550 | 0.0019921 | 0.0237275 |
| SCG5 | -0.5272260 | 0.0023872 | 0.0264362 |
| EMID1 | -0.5267117 | 0.0001908 | 0.0060443 |
| CYP2F1 | -0.5218862 | 0.0000223 | 0.0016607 |
| LINC00996 | -0.5195705 | 0.0015679 | 0.0205904 |
| APOBEC2 | -0.5192123 | 0.0049521 | 0.0412149 |
| KCNA4 | -0.5187887 | 0.0012753 | 0.0183303 |
| RP11-568A7.2 | -0.5180328 | 0.0004542 | 0.0097729 |
| RP4-564M11.2 | -0.5179555 | 0.0024962 | 0.0270719 |
| AC027601.1 | -0.5166162 | 0.0029202 | 0.0297500 |
| AC226118.1 | -0.5162691 | 0.0004802 | 0.0101065 |
| AC005082.12 | -0.5158740 | 0.0009718 | 0.0155756 |
| HLF | -0.5155131 | 0.0000016 | 0.0003844 |
| NAP1L3 | -0.5151662 | 0.0001883 | 0.0060014 |
| LRP1B | -0.5137005 | 0.0009156 | 0.0149731 |
| SLC38A4 | -0.5134971 | 0.0003171 | 0.0080114 |
| UBASH3A | -0.5124762 | 0.0007353 | 0.0130195 |
| FBN1 | -0.5118322 | 0.0000458 | 0.0026455 |
| CPED1 | -0.5102563 | 0.0014392 | 0.0196211 |
| CYP2A13 | -0.5098383 | 0.0020638 | 0.0242722 |
| FAM89A | -0.5095007 | 0.0051090 | 0.0419715 |
| GJA1 | -0.5094236 | 0.0000179 | 0.0014607 |
| FGF18 | -0.5087330 | 0.0043583 | 0.0382518 |
| PROS1 | -0.5079921 | 0.0010033 | 0.0157922 |
| TRBC2 | -0.5054618 | 0.0022070 | 0.0251986 |
| DCX | -0.5051410 | 0.0044268 | 0.0385848 |
| SMOC2 | -0.5050210 | 0.0000904 | 0.0038788 |
| FGF9 | -0.5049568 | 0.0000228 | 0.0016888 |
| CNKSR2 | -0.5044825 | 0.0000795 | 0.0036006 |
| VSTM4 | -0.5034349 | 0.0003624 | 0.0085426 |
| KLRK1 | -0.5032737 | 0.0017614 | 0.0219497 |
| ECM2 | -0.5032527 | 0.0000352 | 0.0022391 |
| CD8B | -0.5011585 | 0.0038495 | 0.0353345 |
| KIAA1462 | -0.5010617 | 0.0020661 | 0.0242722 |
# write.table(resSigDown, "20201112_Up_in_COPD_Bronch.txt", sep = "\t", quote=F)
resSigUp <- resSig[resSig$log2FoldChange > 0.5, ]
resSigUp <- resSigUp[order(resSigUp$log2FoldChange, decreasing = T),]
resSigUp <- resSigUp[,c(2,5,6)]
colnames(resSigUp) <- c("Log2FC", "P-value", "Adj. P-value")
resSigUp %>%
knitr::kable(
format = "html", align = rep("c", ncol(resSig) + 1),
row.names = TRUE
) %>%
kableExtra::kable_styling() %>%
kableExtra::scroll_box(height = "300px")
| Log2FC | P-value | Adj. P-value | |
|---|---|---|---|
| STC1 | 2.2802176 | 0.0000000 | 0.0000010 |
| SLC6A10P | 2.1910697 | 0.0002990 | 0.0077433 |
| Z82214.3 | 1.8690658 | 0.0000007 | 0.0002348 |
| BPIFB6 | 1.8233056 | 0.0000004 | 0.0001674 |
| CTD-3118D7.1 | 1.7859920 | 0.0000187 | 0.0014889 |
| MUC3A | 1.7289481 | 0.0000056 | 0.0007643 |
| APOB | 1.6658811 | 0.0000000 | 0.0000118 |
| PAX6 | 1.6033870 | 0.0004596 | 0.0098152 |
| MUC6 | 1.5711397 | 0.0000025 | 0.0004803 |
| TPO | 1.5209755 | 0.0000000 | 0.0000006 |
| DPCR1 | 1.4355268 | 0.0003097 | 0.0079349 |
| ARHGAP40 | 1.4010723 | 0.0000000 | 0.0000020 |
| PCDH15 | 1.3451918 | 0.0024073 | 0.0265214 |
| BPIFB2 | 1.3307664 | 0.0000035 | 0.0005948 |
| IL17REL | 1.3159170 | 0.0000000 | 0.0000094 |
| CACNA1E | 1.3158698 | 0.0000000 | 0.0000000 |
| GRM7-AS1 | 1.3097725 | 0.0007791 | 0.0135428 |
| RP11-167N4.2 | 1.3036335 | 0.0000007 | 0.0002298 |
| SLC13A5 | 1.3022798 | 0.0000004 | 0.0001513 |
| ALOX15B | 1.2553555 | 0.0000121 | 0.0011855 |
| REG4 | 1.2536849 | 0.0000646 | 0.0032187 |
| CREG2 | 1.2522371 | 0.0001457 | 0.0051982 |
| EDN2 | 1.2235233 | 0.0028463 | 0.0292864 |
| C8orf22 | 1.2221970 | 0.0027706 | 0.0288886 |
| SNTG2 | 1.2159686 | 0.0000000 | 0.0000011 |
| BMP8A | 1.2121615 | 0.0003433 | 0.0083281 |
| RP11-139K4.2 | 1.2103870 | 0.0000380 | 0.0023818 |
| CSF3 | 1.2078871 | 0.0001984 | 0.0061280 |
| RP11-138A9.2 | 1.2018027 | 0.0004080 | 0.0092355 |
| RP11-157E16.1 | 1.1889221 | 0.0000788 | 0.0035892 |
| ANO7 | 1.1720775 | 0.0000000 | 0.0000003 |
| PIRT | 1.1661742 | 0.0009810 | 0.0156338 |
| CHRM1 | 1.1586391 | 0.0000700 | 0.0033416 |
| RP11-481N16.1 | 1.1430760 | 0.0004337 | 0.0094744 |
| SLC25A48 | 1.1391164 | 0.0000179 | 0.0014607 |
| RP11-567M16.2 | 1.1180493 | 0.0003396 | 0.0082711 |
| AL133373.1 | 1.1147990 | 0.0000000 | 0.0000011 |
| C1orf95 | 1.1137259 | 0.0000011 | 0.0002981 |
| FAM189A1 | 1.1130344 | 0.0059601 | 0.0459847 |
| HKDC1 | 1.1095670 | 0.0000003 | 0.0001342 |
| GAPDHP24 | 1.1079986 | 0.0007809 | 0.0135542 |
| PXDN | 1.1079226 | 0.0000000 | 0.0000010 |
| ZDHHC4P1 | 1.1075640 | 0.0000000 | 0.0000147 |
| CDH15 | 1.1048649 | 0.0000497 | 0.0027612 |
| PTHLH | 1.0995579 | 0.0000000 | 0.0000261 |
| RP11-89K21.1 | 1.0968992 | 0.0012437 | 0.0180929 |
| LIPG | 1.0812755 | 0.0000066 | 0.0008342 |
| NTRK2 | 1.0642048 | 0.0000002 | 0.0000909 |
| SIX3 | 1.0582863 | 0.0000797 | 0.0036006 |
| RP11-779P15.2 | 1.0565586 | 0.0014002 | 0.0192783 |
| PMS2P10 | 1.0392064 | 0.0028860 | 0.0295173 |
| IL19 | 1.0178270 | 0.0000120 | 0.0011728 |
| RP11-439L8.3 | 1.0156225 | 0.0000199 | 0.0015513 |
| AC012501.2 | 1.0101285 | 0.0036346 | 0.0341523 |
| B3GNT6 | 1.0066858 | 0.0000423 | 0.0025675 |
| RP11-139K4.4 | 1.0000498 | 0.0000007 | 0.0002298 |
| RP11-333O1.1 | 0.9979751 | 0.0049601 | 0.0412358 |
| AQP7P1 | 0.9953444 | 0.0004687 | 0.0099612 |
| SLCO1B7 | 0.9935182 | 0.0018572 | 0.0226495 |
| AL354898.1 | 0.9930726 | 0.0043948 | 0.0384051 |
| RP11-687D19.1 | 0.9878544 | 0.0007001 | 0.0125690 |
| LEFTY1 | 0.9865289 | 0.0011539 | 0.0173171 |
| STXBP5L | 0.9817248 | 0.0002391 | 0.0068094 |
| MICD | 0.9804493 | 0.0000369 | 0.0023211 |
| RP11-507B12.1 | 0.9629970 | 0.0021586 | 0.0248669 |
| FLNC | 0.9619265 | 0.0000049 | 0.0007152 |
| CGREF1 | 0.9614465 | 0.0002335 | 0.0067105 |
| GOLGA6B | 0.9595250 | 0.0005255 | 0.0106222 |
| SLCO1B3 | 0.9548557 | 0.0000436 | 0.0025946 |
| DUSP5P1 | 0.9477895 | 0.0000039 | 0.0006309 |
| GOLGA7B.1 | 0.9423668 | 0.0029528 | 0.0299979 |
| RP11-16E12.2 | 0.9416867 | 0.0001018 | 0.0041658 |
| FEZF1 | 0.9287649 | 0.0063670 | 0.0479009 |
| FKBP5 | 0.9227220 | 0.0000001 | 0.0000508 |
| NPM1P43 | 0.9211773 | 0.0005307 | 0.0106798 |
| RP11-460N11.3 | 0.9182599 | 0.0015595 | 0.0205364 |
| ZNF467 | 0.9166568 | 0.0000000 | 0.0000168 |
| RP11-395B7.2 | 0.9164471 | 0.0000334 | 0.0021484 |
| CTD-2509G16.3 | 0.9162443 | 0.0004330 | 0.0094744 |
| U3.80 | 0.9097359 | 0.0030444 | 0.0305769 |
| RP11-115D19.1 | 0.9084628 | 0.0004273 | 0.0093990 |
| SSPO | 0.9080064 | 0.0000000 | 0.0000132 |
| RP11-439L8.4 | 0.9058979 | 0.0000470 | 0.0026637 |
| RP11-139K4.1 | 0.8914952 | 0.0000001 | 0.0000379 |
| CDSN | 0.8871000 | 0.0026822 | 0.0282420 |
| CYP17A1 | 0.8842914 | 0.0037402 | 0.0347536 |
| EPS8L3 | 0.8830837 | 0.0009908 | 0.0156741 |
| SLC6A1 | 0.8814102 | 0.0050176 | 0.0415311 |
| AC015987.2 | 0.8711021 | 0.0004431 | 0.0095905 |
| FBN2 | 0.8683692 | 0.0000000 | 0.0000168 |
| LINC00342 | 0.8683322 | 0.0000044 | 0.0006793 |
| RP1-37C10.3 | 0.8666098 | 0.0023047 | 0.0258569 |
| RPL21P112 | 0.8656450 | 0.0022159 | 0.0252246 |
| FAM177B | 0.8630706 | 0.0000044 | 0.0006793 |
| RP11-838N2.8 | 0.8565901 | 0.0006507 | 0.0120028 |
| IDI2-AS1 | 0.8553067 | 0.0010945 | 0.0167282 |
| COMP | 0.8533607 | 0.0020652 | 0.0242722 |
| C1QTNF1 | 0.8525928 | 0.0009821 | 0.0156338 |
| AZGP1 | 0.8478495 | 0.0000006 | 0.0002136 |
| RP11-803D5.4 | 0.8453177 | 0.0000236 | 0.0017277 |
| EEF1DP5 | 0.8400569 | 0.0006702 | 0.0122548 |
| AHSG | 0.8369773 | 0.0048318 | 0.0406150 |
| AC098592.7 | 0.8330522 | 0.0001233 | 0.0047183 |
| RP5-914M6.1 | 0.8324801 | 0.0004806 | 0.0101065 |
| YAP1P1 | 0.8279149 | 0.0032406 | 0.0317538 |
| MTND4P12 | 0.8259292 | 0.0002818 | 0.0074391 |
| CTB-102L5.8 | 0.8249917 | 0.0032962 | 0.0319930 |
| ITGA10 | 0.8216204 | 0.0000006 | 0.0001949 |
| FIGN | 0.8176383 | 0.0000005 | 0.0001701 |
| RP11-10H3.1 | 0.8162534 | 0.0031539 | 0.0312348 |
| LRRC31 | 0.8142625 | 0.0000077 | 0.0009200 |
| RP11-386M24.5 | 0.8137338 | 0.0034447 | 0.0328752 |
| AC144450.2 | 0.8112034 | 0.0000000 | 0.0000071 |
| RP11-527N22.1 | 0.8083172 | 0.0011072 | 0.0168221 |
| FAM157B | 0.8075813 | 0.0024752 | 0.0269577 |
| CUX2 | 0.8075334 | 0.0000302 | 0.0020068 |
| RP11-194N12.2 | 0.8062291 | 0.0013692 | 0.0190958 |
| RN7SKP151 | 0.8049246 | 0.0001865 | 0.0059830 |
| WNT16 | 0.7989340 | 0.0007900 | 0.0135948 |
| RP11-80I15.1 | 0.7961854 | 0.0000128 | 0.0012152 |
| ASNSP3 | 0.7943701 | 0.0000018 | 0.0003930 |
| SEMA6B | 0.7933276 | 0.0023853 | 0.0264362 |
| TDGF1P4 | 0.7871098 | 0.0050168 | 0.0415311 |
| BCAS2P2 | 0.7851954 | 0.0000628 | 0.0031821 |
| SLC17A9 | 0.7810516 | 0.0000018 | 0.0003930 |
| RPLP0P2 | 0.7810449 | 0.0004219 | 0.0093284 |
| ENTPD2 | 0.7809707 | 0.0000000 | 0.0000020 |
| WDR72 | 0.7799025 | 0.0000022 | 0.0004537 |
| GOLGA6L10 | 0.7788106 | 0.0032463 | 0.0317728 |
| RNU5E-6P | 0.7765796 | 0.0005455 | 0.0108481 |
| RP11-508M8.1 | 0.7727333 | 0.0050119 | 0.0415311 |
| AQP7P3 | 0.7713275 | 0.0001727 | 0.0057324 |
| RP11-893F2.9 | 0.7663894 | 0.0005455 | 0.0108481 |
| GOLGA7B | 0.7663690 | 0.0001983 | 0.0061280 |
| U3.7 | 0.7658721 | 0.0024289 | 0.0267082 |
| MUC5AC | 0.7652430 | 0.0001773 | 0.0058281 |
| GPR153 | 0.7650752 | 0.0000055 | 0.0007643 |
| LDLRAD2 | 0.7645421 | 0.0000000 | 0.0000168 |
| DAAM2 | 0.7630483 | 0.0000828 | 0.0036453 |
| AC124944.4 | 0.7617858 | 0.0056907 | 0.0447113 |
| LINC00632 | 0.7602183 | 0.0004096 | 0.0092459 |
| LA16c-425C2.1 | 0.7582489 | 0.0000827 | 0.0036453 |
| CTD-2530H12.7 | 0.7573317 | 0.0001009 | 0.0041363 |
| CTD-2267D19.6 | 0.7553498 | 0.0001489 | 0.0052847 |
| CTD-3193O13.1 | 0.7541919 | 0.0000709 | 0.0033736 |
| CCL24 | 0.7527081 | 0.0061780 | 0.0468771 |
| F5 | 0.7490325 | 0.0000011 | 0.0002858 |
| RP11-2E11.5 | 0.7475000 | 0.0058795 | 0.0455949 |
| RN7SL105P | 0.7472610 | 0.0004983 | 0.0103240 |
| AZGP1P1 | 0.7417958 | 0.0044137 | 0.0385223 |
| RP4-713A8.1 | 0.7396379 | 0.0008328 | 0.0140956 |
| C2CD4A | 0.7374139 | 0.0000440 | 0.0026061 |
| AC073218.2 | 0.7307830 | 0.0011322 | 0.0171098 |
| PTGS2 | 0.7289908 | 0.0001296 | 0.0048450 |
| RP11-5L12.1 | 0.7274469 | 0.0048803 | 0.0408152 |
| DOC2B | 0.7263661 | 0.0006268 | 0.0117429 |
| AC020907.1 | 0.7245049 | 0.0007369 | 0.0130391 |
| ZBTB16 | 0.7241821 | 0.0009144 | 0.0149692 |
| AC138035.1 | 0.7223241 | 0.0015351 | 0.0203407 |
| DHRSX-IT1 | 0.7172868 | 0.0001475 | 0.0052562 |
| PHACTR3 | 0.7168333 | 0.0027491 | 0.0287316 |
| NANOGP7 | 0.7152823 | 0.0000585 | 0.0030453 |
| ELMOD1 | 0.7129683 | 0.0000658 | 0.0032312 |
| SERHL2 | 0.7126315 | 0.0000061 | 0.0007998 |
| RP11-589C21.6 | 0.7122100 | 0.0001930 | 0.0060647 |
| BRINP1 | 0.7089327 | 0.0044142 | 0.0385223 |
| AC006003.3 | 0.7085877 | 0.0011863 | 0.0176073 |
| RP11-259O2.1 | 0.7085502 | 0.0014797 | 0.0199352 |
| NEAT1 | 0.7069154 | 0.0000003 | 0.0001512 |
| KCNN2 | 0.7055893 | 0.0035739 | 0.0337575 |
| RPS20P1 | 0.7052842 | 0.0001361 | 0.0049878 |
| CYP3A5 | 0.7025365 | 0.0002024 | 0.0062135 |
| CPNE4 | 0.6971037 | 0.0001367 | 0.0049968 |
| RP13-726E6.3 | 0.6968872 | 0.0036570 | 0.0342778 |
| RN7SL739P | 0.6968854 | 0.0013355 | 0.0187499 |
| PTPRH | 0.6967019 | 0.0002416 | 0.0068441 |
| DNAJC12 | 0.6965788 | 0.0000185 | 0.0014859 |
| RP11-386M24.6 | 0.6947778 | 0.0003637 | 0.0085553 |
| AC108066.1 | 0.6927396 | 0.0046537 | 0.0397125 |
| TNNI3 | 0.6895294 | 0.0000024 | 0.0004780 |
| REP15 | 0.6863976 | 0.0000160 | 0.0013776 |
| RP11-430B1.1 | 0.6826777 | 0.0020739 | 0.0243187 |
| AP000695.6 | 0.6807910 | 0.0022200 | 0.0252484 |
| Metazoa_SRP.12 | 0.6768366 | 0.0002958 | 0.0076932 |
| ADRA2A | 0.6753578 | 0.0001356 | 0.0049763 |
| TMC7 | 0.6732001 | 0.0000001 | 0.0000729 |
| ENTPD8 | 0.6707694 | 0.0000173 | 0.0014488 |
| RP11-221J22.2 | 0.6689997 | 0.0005659 | 0.0111150 |
| FDPSP3 | 0.6672645 | 0.0000805 | 0.0036201 |
| AF131215.6 | 0.6663677 | 0.0030051 | 0.0303008 |
| TFF1 | 0.6656251 | 0.0025258 | 0.0272698 |
| CTD-2589M5.4 | 0.6655705 | 0.0002820 | 0.0074391 |
| RP11-10J21.4 | 0.6623944 | 0.0064718 | 0.0483631 |
| RP11-480G7.1 | 0.6612726 | 0.0000525 | 0.0028516 |
| RP4-609E1.2 | 0.6612028 | 0.0018409 | 0.0225540 |
| CTC-548K16.6 | 0.6606675 | 0.0000891 | 0.0038393 |
| RN7SL57P | 0.6600234 | 0.0000669 | 0.0032721 |
| RP11-77H9.5 | 0.6588525 | 0.0001544 | 0.0053875 |
| FAM157C | 0.6576799 | 0.0000098 | 0.0010757 |
| RP3-363L9.1 | 0.6566384 | 0.0007351 | 0.0130195 |
| RP11-47G11.2 | 0.6554680 | 0.0003918 | 0.0089710 |
| RP11-74C1.2 | 0.6540906 | 0.0000186 | 0.0014882 |
| JAKMIP3 | 0.6540259 | 0.0012947 | 0.0184917 |
| RP11-120K24.4 | 0.6534771 | 0.0000032 | 0.0005713 |
| RP11-435B5.5 | 0.6517619 | 0.0020961 | 0.0244481 |
| CTD-2047H16.2 | 0.6473474 | 0.0002744 | 0.0073122 |
| CEACAM5 | 0.6468732 | 0.0031817 | 0.0313801 |
| AP000889.3 | 0.6445893 | 0.0048654 | 0.0407301 |
| SPDEF | 0.6439825 | 0.0000319 | 0.0020723 |
| RP5-981O7.2 | 0.6436388 | 0.0000003 | 0.0001390 |
| AC078852.2 | 0.6426335 | 0.0022135 | 0.0252246 |
| MUC1 | 0.6426249 | 0.0000000 | 0.0000043 |
| AC007036.4 | 0.6424753 | 0.0000354 | 0.0022431 |
| RP11-18F14.4 | 0.6418176 | 0.0011714 | 0.0174781 |
| SLC26A2 | 0.6402932 | 0.0000001 | 0.0000508 |
| THBS1 | 0.6378750 | 0.0000419 | 0.0025579 |
| CATSPERB | 0.6363337 | 0.0000000 | 0.0000135 |
| SULT1C2 | 0.6336007 | 0.0010821 | 0.0166011 |
| CTB-193M12.3 | 0.6329112 | 0.0002520 | 0.0069591 |
| RP11-496D24.2 | 0.6324266 | 0.0028561 | 0.0293635 |
| AC092168.2 | 0.6323481 | 0.0001051 | 0.0042738 |
| RP11-297K8.2 | 0.6299306 | 0.0009634 | 0.0154737 |
| PNCK | 0.6294998 | 0.0004467 | 0.0096363 |
| RP11-1191J2.2 | 0.6282962 | 0.0029801 | 0.0301316 |
| AC008132.13 | 0.6267860 | 0.0008807 | 0.0146735 |
| AC112518.3 | 0.6239440 | 0.0000113 | 0.0011414 |
| RN7SKP95 | 0.6213521 | 0.0013808 | 0.0191326 |
| RP11-864J10.2 | 0.6212002 | 0.0016983 | 0.0214305 |
| GS1-122H1.3 | 0.6194692 | 0.0028910 | 0.0295551 |
| CHCHD4P2 | 0.6188037 | 0.0003137 | 0.0079707 |
| KCP | 0.6187811 | 0.0024825 | 0.0270084 |
| ADM2 | 0.6179245 | 0.0000016 | 0.0003661 |
| VN1R51P | 0.6168663 | 0.0005712 | 0.0111520 |
| SLC25A18 | 0.6168032 | 0.0036173 | 0.0340919 |
| RN7SKP24 | 0.6162040 | 0.0000692 | 0.0033167 |
| RP11-447H19.3 | 0.6160178 | 0.0045266 | 0.0390912 |
| UNC5A | 0.6151160 | 0.0059948 | 0.0461162 |
| CTC-244M17.1 | 0.6149821 | 0.0000424 | 0.0025675 |
| SERPINB4 | 0.6147896 | 0.0006177 | 0.0116526 |
| NID2 | 0.6133132 | 0.0052442 | 0.0425079 |
| CTD-2589H19.6 | 0.6127672 | 0.0026819 | 0.0282420 |
| ADORA3 | 0.6125718 | 0.0004376 | 0.0095225 |
| TMEM211 | 0.6123906 | 0.0000039 | 0.0006283 |
| RP11-168F9.2 | 0.6078583 | 0.0044876 | 0.0389508 |
| PRSS16 | 0.6077625 | 0.0000000 | 0.0000236 |
| AL627309.1 | 0.6074216 | 0.0011047 | 0.0168054 |
| NARF-IT1 | 0.6071972 | 0.0000040 | 0.0006422 |
| RP11-1036E20.9 | 0.6062101 | 0.0000001 | 0.0000502 |
| RP11-380J14.1 | 0.6057669 | 0.0000212 | 0.0016032 |
| RP11-458F8.2 | 0.6055018 | 0.0033041 | 0.0320429 |
| RP11-324E6.6 | 0.6049054 | 0.0053533 | 0.0429934 |
| RPS4XP22 | 0.6033927 | 0.0007829 | 0.0135542 |
| RP11-797A18.4 | 0.6032046 | 0.0000004 | 0.0001627 |
| AC016559.1 | 0.6028178 | 0.0015340 | 0.0203407 |
| IRAK3 | 0.6021432 | 0.0000000 | 0.0000251 |
| SHROOM1 | 0.6003467 | 0.0000014 | 0.0003441 |
| RP11-3K24.1 | 0.5998078 | 0.0013500 | 0.0189014 |
| TCN1 | 0.5989780 | 0.0019457 | 0.0233376 |
| MYLK3 | 0.5987669 | 0.0001154 | 0.0045048 |
| RP11-164H5.1 | 0.5984192 | 0.0003574 | 0.0084713 |
| RP11-49O14.3 | 0.5980525 | 0.0000104 | 0.0011029 |
| HK2P1 | 0.5974026 | 0.0040816 | 0.0366273 |
| AC138517.1 | 0.5959937 | 0.0040339 | 0.0363522 |
| RP11-112L18.1 | 0.5952027 | 0.0020410 | 0.0241032 |
| ATP5A1P3 | 0.5946478 | 0.0000096 | 0.0010602 |
| ANKRD36C | 0.5933542 | 0.0004807 | 0.0101065 |
| CTD-2547H18.1 | 0.5928804 | 0.0010601 | 0.0163950 |
| PLEKHD1 | 0.5911511 | 0.0003312 | 0.0081736 |
| RP11-359B20.1 | 0.5908479 | 0.0001330 | 0.0049102 |
| RPL7L1P2 | 0.5905607 | 0.0000305 | 0.0020171 |
| PYCR1 | 0.5900049 | 0.0000047 | 0.0007035 |
| LBX2 | 0.5895572 | 0.0003346 | 0.0082269 |
| AC005077.14 | 0.5888899 | 0.0000005 | 0.0001878 |
| RP11-131K5.1 | 0.5877011 | 0.0012684 | 0.0182802 |
| DQX1 | 0.5870439 | 0.0000000 | 0.0000168 |
| CTB-11I22.2 | 0.5844118 | 0.0004153 | 0.0092943 |
| AC110619.1 | 0.5820199 | 0.0002023 | 0.0062135 |
| LAP3P1 | 0.5799572 | 0.0000106 | 0.0011099 |
| AC144450.1 | 0.5798538 | 0.0010304 | 0.0160632 |
| GS1-122H1.1 | 0.5794545 | 0.0032951 | 0.0319930 |
| RN7SKP239 | 0.5790295 | 0.0003293 | 0.0081676 |
| ADAMDEC1 | 0.5787993 | 0.0028423 | 0.0292803 |
| RP11-195B21.3 | 0.5758041 | 0.0010020 | 0.0157841 |
| RP11-27M24.2 | 0.5755681 | 0.0056420 | 0.0444645 |
| AP001468.1 | 0.5747175 | 0.0065673 | 0.0488126 |
| CXCL2 | 0.5733062 | 0.0053491 | 0.0429866 |
| CCDC144NL | 0.5717484 | 0.0055756 | 0.0441309 |
| RP11-100J16.4 | 0.5713423 | 0.0028455 | 0.0292864 |
| RP11-381G8.1 | 0.5713423 | 0.0028455 | 0.0292864 |
| AC097468.4 | 0.5709202 | 0.0011236 | 0.0170010 |
| PRKXP1 | 0.5706856 | 0.0039136 | 0.0356553 |
| CTHRC1 | 0.5698637 | 0.0065886 | 0.0488952 |
| RP11-486O13.4 | 0.5694970 | 0.0027173 | 0.0284954 |
| RP11-353J17.3 | 0.5691443 | 0.0002440 | 0.0068717 |
| ITPKB-IT1 | 0.5680758 | 0.0023671 | 0.0262924 |
| RP11-332H18.3 | 0.5664058 | 0.0003317 | 0.0081736 |
| RP5-1041C10.3 | 0.5660460 | 0.0000057 | 0.0007752 |
| CPE | 0.5652087 | 0.0001208 | 0.0046461 |
| ABO | 0.5647148 | 0.0000169 | 0.0014221 |
| BACE2-IT1 | 0.5637973 | 0.0022528 | 0.0254731 |
| RP11-554D13.1 | 0.5629611 | 0.0060048 | 0.0461318 |
| PSORS1C1 | 0.5608379 | 0.0051067 | 0.0419715 |
| RP3-342P20.2 | 0.5603868 | 0.0000796 | 0.0036006 |
| JPH2 | 0.5601865 | 0.0012032 | 0.0177501 |
| AF131215.4 | 0.5587864 | 0.0000001 | 0.0000536 |
| PLAT | 0.5580129 | 0.0012985 | 0.0185031 |
| MSLN | 0.5576314 | 0.0000032 | 0.0005681 |
| NDUFB8P2 | 0.5574481 | 0.0021651 | 0.0249220 |
| GPR37 | 0.5561644 | 0.0003205 | 0.0080581 |
| RP11-534P19.1 | 0.5545697 | 0.0046406 | 0.0396764 |
| AC017060.1 | 0.5533333 | 0.0005884 | 0.0113528 |
| AC009061.1 | 0.5531123 | 0.0004010 | 0.0091407 |
| RPS16P5 | 0.5518405 | 0.0000625 | 0.0031779 |
| CTD-2201E18.5 | 0.5511306 | 0.0022534 | 0.0254731 |
| RP11-555K12.2 | 0.5511138 | 0.0066352 | 0.0490284 |
| CHAD | 0.5510209 | 0.0000543 | 0.0029294 |
| BHLHA15 | 0.5503049 | 0.0010218 | 0.0159781 |
| AC114737.3 | 0.5494690 | 0.0007919 | 0.0136089 |
| C1orf64 | 0.5492243 | 0.0046336 | 0.0396561 |
| AC091171.1 | 0.5492018 | 0.0004867 | 0.0101666 |
| STEAP3-AS1 | 0.5467683 | 0.0013243 | 0.0186633 |
| PDCL3P6 | 0.5466952 | 0.0041412 | 0.0369561 |
| AC015987.1 | 0.5464583 | 0.0007862 | 0.0135833 |
| RP13-870H17.3 | 0.5459774 | 0.0009544 | 0.0153929 |
| CTD-2547L24.4 | 0.5459735 | 0.0063446 | 0.0477885 |
| RP11-680G24.4 | 0.5449092 | 0.0040439 | 0.0363866 |
| FTLP14 | 0.5435340 | 0.0012977 | 0.0185015 |
| CTA-331F8.1 | 0.5412948 | 0.0017231 | 0.0216636 |
| RP11-317F20.2 | 0.5395444 | 0.0003681 | 0.0086214 |
| RP1-168P16.1 | 0.5394518 | 0.0027531 | 0.0287532 |
| LCN2 | 0.5391316 | 0.0015233 | 0.0202679 |
| RP11-99A1.2 | 0.5390547 | 0.0000056 | 0.0007711 |
| BTNL9 | 0.5387906 | 0.0011193 | 0.0169565 |
| RP11-214O1.3 | 0.5385319 | 0.0003153 | 0.0079869 |
| XBP1P1 | 0.5381186 | 0.0003394 | 0.0082711 |
| RP11-21A7A.3 | 0.5374270 | 0.0020428 | 0.0241081 |
| RP11-982M15.8 | 0.5353255 | 0.0022764 | 0.0256514 |
| RTEL1-TNFRSF6B | 0.5348836 | 0.0000468 | 0.0026593 |
| RP11-241J12.3 | 0.5344845 | 0.0012507 | 0.0181433 |
| IL1R2 | 0.5343087 | 0.0022972 | 0.0258175 |
| CTD-2555A7.2 | 0.5332711 | 0.0052197 | 0.0424117 |
| HCG20 | 0.5328531 | 0.0045142 | 0.0390235 |
| RP11-327F22.6 | 0.5318638 | 0.0063726 | 0.0479036 |
| RP11-34P13.13 | 0.5315750 | 0.0000275 | 0.0018786 |
| CYP1B1-AS1 | 0.5315748 | 0.0016838 | 0.0213630 |
| RP11-318K15.2 | 0.5314635 | 0.0006216 | 0.0116919 |
| AC026806.2 | 0.5310165 | 0.0000008 | 0.0002426 |
| RP11-1396O13.2 | 0.5301164 | 0.0016456 | 0.0212110 |
| RP11-449P15.1 | 0.5300198 | 0.0005871 | 0.0113420 |
| NKX3-1 | 0.5288490 | 0.0020963 | 0.0244481 |
| HSD11B2 | 0.5277233 | 0.0001276 | 0.0047993 |
| KLF7-IT1 | 0.5277020 | 0.0000275 | 0.0018786 |
| RP11-206L10.3 | 0.5274511 | 0.0000180 | 0.0014607 |
| ALDH1L2 | 0.5271217 | 0.0003375 | 0.0082498 |
| RP11-68I3.11 | 0.5252756 | 0.0000564 | 0.0029806 |
| AC139426.2 | 0.5245291 | 0.0001720 | 0.0057243 |
| RP11-356M20.3 | 0.5233429 | 0.0004226 | 0.0093351 |
| PDPK2 | 0.5219127 | 0.0000106 | 0.0011099 |
| RP11-384C4.6 | 0.5215964 | 0.0000887 | 0.0038302 |
| CTD-3222D19.5 | 0.5213488 | 0.0042189 | 0.0373421 |
| GRM8 | 0.5205974 | 0.0022475 | 0.0254600 |
| RP11-158M2.5 | 0.5205745 | 0.0055090 | 0.0437515 |
| LINC01002 | 0.5194631 | 0.0011715 | 0.0174781 |
| OMP | 0.5187381 | 0.0046976 | 0.0399109 |
| RP11-553A21.3 | 0.5182660 | 0.0055072 | 0.0437513 |
| RP11-443F16.1 | 0.5181958 | 0.0020657 | 0.0242722 |
| AP000347.4 | 0.5180575 | 0.0013345 | 0.0187456 |
| RP11-231C14.4 | 0.5180177 | 0.0000414 | 0.0025355 |
| CTB-181H17.1 | 0.5175276 | 0.0001863 | 0.0059830 |
| AC000089.3 | 0.5168444 | 0.0000009 | 0.0002534 |
| CTD-2619J13.8 | 0.5165587 | 0.0051089 | 0.0419715 |
| RP11-453A12.1 | 0.5162805 | 0.0027785 | 0.0289363 |
| RP11-422N16.3 | 0.5149038 | 0.0000462 | 0.0026553 |
| RP11-458F8.4 | 0.5148342 | 0.0015087 | 0.0201796 |
| HMSD | 0.5148289 | 0.0018162 | 0.0223798 |
| CTB-131B5.2 | 0.5146960 | 0.0001450 | 0.0051884 |
| RP11-305L7.5 | 0.5146866 | 0.0033579 | 0.0323840 |
| GJA6P | 0.5146277 | 0.0002493 | 0.0069157 |
| SYT8 | 0.5140831 | 0.0000748 | 0.0035025 |
| FOXA3 | 0.5140588 | 0.0001090 | 0.0043815 |
| AC010525.7 | 0.5138022 | 0.0001906 | 0.0060443 |
| RAB43 | 0.5137079 | 0.0000003 | 0.0001463 |
| RP1-308E4.1 | 0.5136772 | 0.0065726 | 0.0488182 |
| LINC00930 | 0.5129701 | 0.0016766 | 0.0213349 |
| FUT6 | 0.5123183 | 0.0000002 | 0.0000781 |
| RP11-404P21.5 | 0.5120947 | 0.0021083 | 0.0245224 |
| RP11-392E22.12 | 0.5120726 | 0.0000154 | 0.0013398 |
| RABGAP1L-IT1 | 0.5120653 | 0.0000086 | 0.0009878 |
| SLC25A47P1 | 0.5119896 | 0.0000164 | 0.0013934 |
| RP11-281P23.2 | 0.5117555 | 0.0016227 | 0.0210554 |
| NEK6 | 0.5112889 | 0.0000001 | 0.0000388 |
| RP11-1082L8.1 | 0.5106343 | 0.0047585 | 0.0402320 |
| AC019117.2 | 0.5103779 | 0.0007883 | 0.0135935 |
| CTB-11I22.1 | 0.5102449 | 0.0062128 | 0.0470565 |
| RP11-392E22.5 | 0.5101933 | 0.0004160 | 0.0092992 |
| RP11-305O4.2 | 0.5101464 | 0.0003069 | 0.0079015 |
| RP11-982M15.6 | 0.5099017 | 0.0028238 | 0.0291830 |
| AC138035.2 | 0.5098157 | 0.0007431 | 0.0130941 |
| AK4P4 | 0.5090954 | 0.0049702 | 0.0412850 |
| RP1-313L4.3 | 0.5090926 | 0.0060696 | 0.0464247 |
| RN7SL23P | 0.5087898 | 0.0010104 | 0.0158478 |
| RP11-365D23.4 | 0.5074868 | 0.0016455 | 0.0212110 |
| ARMC12 | 0.5071957 | 0.0029788 | 0.0301316 |
| ATP10B | 0.5065195 | 0.0026248 | 0.0279122 |
| SLC16A14 | 0.5055594 | 0.0000393 | 0.0024466 |
| RP11-16E23.3 | 0.5046668 | 0.0001399 | 0.0050487 |
| ANKRD18A.1 | 0.5043259 | 0.0000334 | 0.0021484 |
| TFCP2L1 | 0.5041815 | 0.0001626 | 0.0055436 |
| CDC42EP5 | 0.5038609 | 0.0000471 | 0.0026642 |
| RP11-163G10.2 | 0.5033655 | 0.0001262 | 0.0047751 |
| PKHD1L1 | 0.5028688 | 0.0028809 | 0.0294831 |
| PPIAP10 | 0.5027406 | 0.0004188 | 0.0093152 |
| CTC-251D13.1 | 0.5026642 | 0.0009107 | 0.0149607 |
| SEMA3B | 0.5020373 | 0.0000131 | 0.0012259 |
| RP1-5O6.4 | 0.5019920 | 0.0002717 | 0.0072760 |
| ANO1 | 0.5011846 | 0.0007084 | 0.0126646 |
| FBXO36-IT1 | 0.5010788 | 0.0003155 | 0.0079869 |
| RPL19P12 | 0.5007875 | 0.0002096 | 0.0062863 |
| AC005831.1 | 0.5003057 | 0.0000062 | 0.0008023 |
# write.table(resSigUp, "20201112_Down_in_COPD_Bronch.txt", sep = "\t", quote=F)
Differentially expressed genes were checked for overlap with the 98 genes from the COPD signature from Steiling et al, 2013
#Preprocessing. Run ahead of time and comment out when knitting Rmd
names(steilingGenes) <- "Names"
steilingSignature <- steilingGenes$Names
steilingUp <- head(steilingSignature,54)
#create mart object, this is for homo sapiens
mart <- useMart(biomart = "ensembl", dataset = "hsapiens_gene_ensembl")
upBM <- getBM(filters= "hgnc_symbol", attributes= c("ensembl_gene_id","hgnc_symbol"),values=steilingUp,mart= mart)
upBM <- upBM[upBM$ensembl_gene_id %in% rownames(assay(seBronch)),]
# write.table(upBM$ensembl_gene_id, "20201102_SteilingUp_Genelist.grp", sep = "\t", quote = F, col.names = F, row.names = F)
steilingDown <- tail(steilingSignature,44)
downBM <- getBM(filters= "hgnc_symbol", attributes= c("ensembl_gene_id","hgnc_symbol"),values=steilingDown,mart= mart)
downBM <- downBM[-32,]
# write.table(downBM$ensembl_gene_id, "20201102_SteilingDown_Genelist.grp", sep = "\t", quote = F, col.names = F, row.names = F)
#Send to GSEA 11/3/2020
#Check for overlap:
upoverlap <- sum(downBM$hgnc_symbol %in% rownames(resSigUp))
upoverlapgenes <- downBM$hgnc_symbol[downBM$hgnc_symbol %in% rownames(resSigUp)]
downoverlap <- sum(upBM$hgnc_symbol %in% rownames(resSigDown))
downoverlapgenes <- upBM$hgnc_symbol[upBM$hgnc_symbol %in% rownames(resSigDown)]
Overall, of the 54 genes associated with increase of COPD status, 0 were differentially expressed in patients considered to be of COPD status. These are: . Of the 44 genes associated with decrease of COPD status, 0 were differentially expressed in patients considered to be of COPD status. These are: .
resSigUp <- read.table("20201112_Down_in_COPD_Bronch.txt", sep = "\t")
rownames(resSigUp)
## [1] "STC1" "SLC6A10P" "Z82214.3" "BPIFB6"
## [5] "CTD-3118D7.1" "MUC3A" "APOB" "PAX6"
## [9] "MUC6" "TPO" "DPCR1" "ARHGAP40"
## [13] "PCDH15" "BPIFB2" "IL17REL" "CACNA1E"
## [17] "GRM7-AS1" "RP11-167N4.2" "SLC13A5" "ALOX15B"
## [21] "REG4" "CREG2" "EDN2" "C8orf22"
## [25] "SNTG2" "BMP8A" "RP11-139K4.2" "CSF3"
## [29] "RP11-138A9.2" "RP11-157E16.1" "ANO7" "PIRT"
## [33] "CHRM1" "RP11-481N16.1" "SLC25A48" "RP11-567M16.2"
## [37] "AL133373.1" "C1orf95" "FAM189A1" "HKDC1"
## [41] "GAPDHP24" "PXDN" "ZDHHC4P1" "CDH15"
## [45] "PTHLH" "RP11-89K21.1" "LIPG" "NTRK2"
## [49] "SIX3" "RP11-779P15.2" "PMS2P10" "IL19"
## [53] "RP11-439L8.3" "AC012501.2" "B3GNT6" "RP11-139K4.4"
## [57] "RP11-333O1.1" "AQP7P1" "SLCO1B7" "AL354898.1"
## [61] "RP11-687D19.1" "LEFTY1" "STXBP5L" "MICD"
## [65] "RP11-507B12.1" "FLNC" "CGREF1" "GOLGA6B"
## [69] "SLCO1B3" "DUSP5P1" "GOLGA7B.1" "RP11-16E12.2"
## [73] "FEZF1" "FKBP5" "NPM1P43" "RP11-460N11.3"
## [77] "ZNF467" "RP11-395B7.2" "CTD-2509G16.3" "U3.80"
## [81] "RP11-115D19.1" "SSPO" "RP11-439L8.4" "RP11-139K4.1"
## [85] "CDSN" "CYP17A1" "EPS8L3" "SLC6A1"
## [89] "AC015987.2" "FBN2" "LINC00342" "RP1-37C10.3"
## [93] "RPL21P112" "FAM177B" "RP11-838N2.8" "IDI2-AS1"
## [97] "COMP" "C1QTNF1" "AZGP1" "RP11-803D5.4"
## [101] "EEF1DP5" "AHSG" "AC098592.7" "RP5-914M6.1"
## [105] "YAP1P1" "MTND4P12" "CTB-102L5.8" "ITGA10"
## [109] "FIGN" "RP11-10H3.1" "LRRC31" "RP11-386M24.5"
## [113] "AC144450.2" "RP11-527N22.1" "FAM157B" "CUX2"
## [117] "RP11-194N12.2" "RN7SKP151" "WNT16" "RP11-80I15.1"
## [121] "ASNSP3" "SEMA6B" "TDGF1P4" "BCAS2P2"
## [125] "SLC17A9" "RPLP0P2" "ENTPD2" "WDR72"
## [129] "GOLGA6L10" "RNU5E-6P" "RP11-508M8.1" "AQP7P3"
## [133] "RP11-893F2.9" "GOLGA7B" "U3.7" "MUC5AC"
## [137] "GPR153" "LDLRAD2" "DAAM2" "AC124944.4"
## [141] "LINC00632" "LA16c-425C2.1" "CTD-2530H12.7" "CTD-2267D19.6"
## [145] "CTD-3193O13.1" "CCL24" "F5" "RP11-2E11.5"
## [149] "RN7SL105P" "AZGP1P1" "RP4-713A8.1" "C2CD4A"
## [153] "AC073218.2" "PTGS2" "RP11-5L12.1" "DOC2B"
## [157] "AC020907.1" "ZBTB16" "AC138035.1" "DHRSX-IT1"
## [161] "PHACTR3" "NANOGP7" "ELMOD1" "SERHL2"
## [165] "RP11-589C21.6" "BRINP1" "AC006003.3" "RP11-259O2.1"
## [169] "NEAT1" "KCNN2" "RPS20P1" "CYP3A5"
## [173] "CPNE4" "RP13-726E6.3" "RN7SL739P" "PTPRH"
## [177] "DNAJC12" "RP11-386M24.6" "AC108066.1" "TNNI3"
## [181] "REP15" "RP11-430B1.1" "AP000695.6" "Metazoa_SRP.12"
## [185] "ADRA2A" "TMC7" "ENTPD8" "RP11-221J22.2"
## [189] "FDPSP3" "AF131215.6" "TFF1" "CTD-2589M5.4"
## [193] "RP11-10J21.4" "RP11-480G7.1" "RP4-609E1.2" "CTC-548K16.6"
## [197] "RN7SL57P" "RP11-77H9.5" "FAM157C" "RP3-363L9.1"
## [201] "RP11-47G11.2" "RP11-74C1.2" "JAKMIP3" "RP11-120K24.4"
## [205] "RP11-435B5.5" "CTD-2047H16.2" "CEACAM5" "AP000889.3"
## [209] "SPDEF" "RP5-981O7.2" "AC078852.2" "MUC1"
## [213] "AC007036.4" "RP11-18F14.4" "SLC26A2" "THBS1"
## [217] "CATSPERB" "SULT1C2" "CTB-193M12.3" "RP11-496D24.2"
## [221] "AC092168.2" "RP11-297K8.2" "PNCK" "RP11-1191J2.2"
## [225] "AC008132.13" "AC112518.3" "RN7SKP95" "RP11-864J10.2"
## [229] "GS1-122H1.3" "CHCHD4P2" "KCP" "ADM2"
## [233] "VN1R51P" "SLC25A18" "RN7SKP24" "RP11-447H19.3"
## [237] "UNC5A" "CTC-244M17.1" "SERPINB4" "NID2"
## [241] "CTD-2589H19.6" "ADORA3" "TMEM211" "RP11-168F9.2"
## [245] "PRSS16" "AL627309.1" "NARF-IT1" "RP11-1036E20.9"
## [249] "RP11-380J14.1" "RP11-458F8.2" "RP11-324E6.6" "RPS4XP22"
## [253] "RP11-797A18.4" "AC016559.1" "IRAK3" "SHROOM1"
## [257] "RP11-3K24.1" "TCN1" "MYLK3" "RP11-164H5.1"
## [261] "RP11-49O14.3" "HK2P1" "AC138517.1" "RP11-112L18.1"
## [265] "ATP5A1P3" "ANKRD36C" "CTD-2547H18.1" "PLEKHD1"
## [269] "RP11-359B20.1" "RPL7L1P2" "PYCR1" "LBX2"
## [273] "AC005077.14" "RP11-131K5.1" "DQX1" "CTB-11I22.2"
## [277] "AC110619.1" "LAP3P1" "AC144450.1" "GS1-122H1.1"
## [281] "RN7SKP239" "ADAMDEC1" "RP11-195B21.3" "RP11-27M24.2"
## [285] "AP001468.1" "CXCL2" "CCDC144NL" "RP11-100J16.4"
## [289] "RP11-381G8.1" "AC097468.4" "PRKXP1" "CTHRC1"
## [293] "RP11-486O13.4" "RP11-353J17.3" "ITPKB-IT1" "RP11-332H18.3"
## [297] "RP5-1041C10.3" "CPE" "ABO" "BACE2-IT1"
## [301] "RP11-554D13.1" "PSORS1C1" "RP3-342P20.2" "JPH2"
## [305] "AF131215.4" "PLAT" "MSLN" "NDUFB8P2"
## [309] "GPR37" "RP11-534P19.1" "AC017060.1" "AC009061.1"
## [313] "RPS16P5" "CTD-2201E18.5" "RP11-555K12.2" "CHAD"
## [317] "BHLHA15" "AC114737.3" "C1orf64" "AC091171.1"
## [321] "STEAP3-AS1" "PDCL3P6" "AC015987.1" "RP13-870H17.3"
## [325] "CTD-2547L24.4" "RP11-680G24.4" "FTLP14" "CTA-331F8.1"
## [329] "RP11-317F20.2" "RP1-168P16.1" "LCN2" "RP11-99A1.2"
## [333] "BTNL9" "RP11-214O1.3" "XBP1P1" "RP11-21A7A.3"
## [337] "RP11-982M15.8" "RTEL1-TNFRSF6B" "RP11-241J12.3" "IL1R2"
## [341] "CTD-2555A7.2" "HCG20" "RP11-327F22.6" "RP11-34P13.13"
## [345] "CYP1B1-AS1" "RP11-318K15.2" "AC026806.2" "RP11-1396O13.2"
## [349] "RP11-449P15.1" "NKX3-1" "HSD11B2" "KLF7-IT1"
## [353] "RP11-206L10.3" "ALDH1L2" "RP11-68I3.11" "AC139426.2"
## [357] "RP11-356M20.3" "PDPK2" "RP11-384C4.6" "CTD-3222D19.5"
## [361] "GRM8" "RP11-158M2.5" "LINC01002" "OMP"
## [365] "RP11-553A21.3" "RP11-443F16.1" "AP000347.4" "RP11-231C14.4"
## [369] "CTB-181H17.1" "AC000089.3" "CTD-2619J13.8" "RP11-453A12.1"
## [373] "RP11-422N16.3" "RP11-458F8.4" "HMSD" "CTB-131B5.2"
## [377] "RP11-305L7.5" "GJA6P" "SYT8" "FOXA3"
## [381] "AC010525.7" "RAB43" "RP1-308E4.1" "LINC00930"
## [385] "FUT6" "RP11-404P21.5" "RP11-392E22.12" "RABGAP1L-IT1"
## [389] "SLC25A47P1" "RP11-281P23.2" "NEK6" "RP11-1082L8.1"
## [393] "AC019117.2" "CTB-11I22.1" "RP11-392E22.5" "RP11-305O4.2"
## [397] "RP11-982M15.6" "AC138035.2" "AK4P4" "RP1-313L4.3"
## [401] "RN7SL23P" "RP11-365D23.4" "ARMC12" "ATP10B"
## [405] "SLC16A14" "RP11-16E23.3" "ANKRD18A.1" "TFCP2L1"
## [409] "CDC42EP5" "RP11-163G10.2" "PKHD1L1" "PPIAP10"
## [413] "CTC-251D13.1" "SEMA3B" "RP1-5O6.4" "ANO1"
## [417] "FBXO36-IT1" "RPL19P12" "AC005831.1"
Gene set enrichment analysis was conducted using genes associated with COPD status from Steiling et al, 2013. The preranked version of GSEA was performed on normalized counts generated from DESeq2. The rank was generated in ascending order of log2 fold change values outputted from DESeq2.
Model used: ~Smoking status + Age + TIN + COPD status
54 Genes associated with increase in COPD status were used for GSEA.
GSEA <- c(0.685,2.17,0.0,0.0, 0.0)
GSEA <- as.data.frame(as.matrix(GSEA))
rownames(GSEA) <- c("Enrichment Score",
"Normalized Enrichment Score",
"Nominal p-value",
"FDR q-value",
"FWER q-value")
colnames(GSEA) <- c("Upregulated in current smokers")
GSEA %>%
knitr::kable(
format = "html", align = rep("c", ncol(GSEA) + 1),
row.names = TRUE
) %>%
kableExtra::kable_styling() %>%
kableExtra::scroll_box(height = "200px")
| Upregulated in current smokers | |
|---|---|
| Enrichment Score | 0.685 |
| Normalized Enrichment Score | 2.170 |
| Nominal p-value | 0.000 |
| FDR q-value | 0.000 |
| FWER q-value | 0.000 |
gsea_details1 <- read.csv("/restricted/projectnb/camplab/home/ykoga07/DECAMP/Novartis/Analysis/1stPass/GSEA_Increase_in_COPD_PreRank_Bronch.csv", row.names = 1)
colnames(gsea_details1) <- gsub("\\.", "_", colnames(gsea_details1))
gsea_details1 <- merge(upBM, gsea_details1, by.x = "ensembl_gene_id", by.y = "ENSEMBL_GENEID")
gsea_details1 <- gsea_details1[order(gsea_details1$RANK_IN_GENE_LIST),]
gsea_details1 %>%
knitr::kable(
format = "html", align = rep("c", ncol(gsea_details1) + 1),
row.names = FALSE
) %>%
kableExtra::kable_styling() %>%
kableExtra::scroll_box(height = "300px")
| ensembl_gene_id | hgnc_symbol | RANK_IN_GENE_LIST | RANK_METRIC_SCORE | RUNNING_ES | CORE_ENRICHMENT |
|---|---|---|---|---|---|
| ENSG00000111700 | SLCO1B3 | 301 | 0.788 | 0.0416 | Yes |
| ENSG00000105388 | CEACAM5 | 369 | 0.746 | 0.0871 | Yes |
| ENSG00000134827 | TCN1 | 596 | 0.646 | 0.1218 | Yes |
| ENSG00000155850 | SLC26A2 | 672 | 0.621 | 0.1592 | Yes |
| ENSG00000073756 | PTGS2 | 936 | 0.553 | 0.1870 | Yes |
| ENSG00000133962 | CATSPERB | 960 | 0.548 | 0.2211 | Yes |
| ENSG00000140297 | GCNT3 | 1089 | 0.531 | 0.2512 | Yes |
| ENSG00000137440 | FGFBP1 | 1132 | 0.525 | 0.2834 | Yes |
| ENSG00000128683 | GAD1 | 1197 | 0.516 | 0.3143 | Yes |
| ENSG00000090376 | IRAK3 | 1228 | 0.510 | 0.3459 | Yes |
| ENSG00000180438 | TPRXL | 1312 | 0.498 | 0.3751 | Yes |
| ENSG00000169116 | PARM1 | 1343 | 0.494 | 0.4056 | Yes |
| ENSG00000115590 | IL1R2 | 1475 | 0.476 | 0.4322 | Yes |
| ENSG00000118322 | ATP10B | 1505 | 0.473 | 0.4614 | Yes |
| ENSG00000156535 | CD109 | 1550 | 0.468 | 0.4899 | Yes |
| ENSG00000171124 | FUT3 | 1597 | 0.462 | 0.5179 | Yes |
| ENSG00000188761 | BCL2L15 | 1729 | 0.448 | 0.5427 | Yes |
| ENSG00000114638 | UPK1B | 1838 | 0.438 | 0.5675 | Yes |
| ENSG00000113657 | DPYSL3 | 2472 | 0.391 | 0.5748 | Yes |
| ENSG00000176907 | TCIM | 2502 | 0.389 | 0.5987 | Yes |
| ENSG00000144452 | ABCA12 | 2769 | 0.374 | 0.6150 | Yes |
| ENSG00000148346 | LCN2 | 2818 | 0.371 | 0.6372 | Yes |
| ENSG00000116711 | PLA2G4A | 2933 | 0.365 | 0.6572 | Yes |
| ENSG00000145113 | MUC4 | 3391 | 0.343 | 0.6663 | Yes |
| ENSG00000173702 | MUC13 | 3485 | 0.339 | 0.6853 | Yes |
| ENSG00000029153 | ARNTL2 | 4272 | 0.304 | 0.6828 | No |
| ENSG00000256870 | SLC5A8 | 4939 | 0.281 | 0.6822 | No |
| ENSG00000135976 | ANKRD36 | 6183 | 0.239 | 0.6631 | No |
| ENSG00000102359 | SRPX2 | 6599 | 0.227 | 0.6660 | No |
| ENSG00000244734 | HBB | 7359 | 0.207 | 0.6581 | No |
| ENSG00000108242 | CYP2C18 | 7378 | 0.207 | 0.6707 | No |
| ENSG00000147697 | GSDMC | 9417 | 0.156 | 0.6243 | No |
| ENSG00000136231 | IGF2BP3 | 11562 | 0.116 | 0.5724 | No |
| ENSG00000156689 | GLYATL2 | 11654 | 0.115 | 0.5772 | No |
| ENSG00000148965 | SAA4 | 14316 | 0.074 | 0.5083 | No |
| ENSG00000173432 | SAA1 | 14899 | 0.066 | 0.4963 | No |
| ENSG00000168412 | MTNR1A | 16245 | 0.050 | 0.4623 | No |
| ENSG00000091137 | SLC26A4 | 17027 | 0.041 | 0.4433 | No |
| ENSG00000094755 | GABRP | 17043 | 0.040 | 0.4454 | No |
| ENSG00000243649 | CFB | 17228 | 0.038 | 0.4428 | No |
| ENSG00000134339 | SAA2 | 19266 | 0.016 | 0.3875 | No |
| ENSG00000242515 | UGT1A10 | 19307 | 0.016 | 0.3874 | No |
| ENSG00000166920 | C15orf48 | 19523 | 0.014 | 0.3823 | No |
| ENSG00000131203 | IDO1 | 23639 | -0.030 | 0.2704 | No |
| ENSG00000261857 | MIA | 24366 | -0.038 | 0.2528 | No |
| ENSG00000197641 | SERPINB13 | 25959 | -0.058 | 0.2125 | No |
| ENSG00000163606 | CD200R1 | 26407 | -0.064 | 0.2042 | No |
| ENSG00000204616 | TRIM31 | 27454 | -0.080 | 0.1803 | No |
| ENSG00000138166 | DUSP5 | 29914 | -0.130 | 0.1206 | No |
| ENSG00000134762 | DSC3 | 30044 | -0.133 | 0.1254 | No |
| ENSG00000123358 | NR4A1 | 30792 | -0.154 | 0.1146 | No |
| ENSG00000170345 | FOS | 31541 | -0.179 | 0.1052 | No |
| ENSG00000041982 | TNC | 31618 | -0.182 | 0.1147 | No |
| ENSG00000153802 | TMPRSS11D | 32061 | -0.200 | 0.1152 | No |
44 Genes associated with decrease in COPD status were used for GSEA.
GSEA <- c(0.612,2.11,0.0,0.0, 0.0)
GSEA <- as.data.frame(as.matrix(GSEA))
rownames(GSEA) <- c("Enrichment Score",
"Normalized Enrichment Score",
"Nominal p-value",
"FDR q-value",
"FWER q-value")
colnames(GSEA) <- c("Downregulated in current smokers")
GSEA %>%
knitr::kable(
format = "html", align = rep("c", ncol(GSEA) + 1),
row.names = TRUE
) %>%
kableExtra::kable_styling() %>%
kableExtra::scroll_box(height = "200px")
| Downregulated in current smokers | |
|---|---|
| Enrichment Score | 0.612 |
| Normalized Enrichment Score | 2.110 |
| Nominal p-value | 0.000 |
| FDR q-value | 0.000 |
| FWER q-value | 0.000 |
gsea_details2 <- read.csv("/restricted/projectnb/camplab/home/ykoga07/DECAMP/Novartis/Analysis/1stPass/GSEA_Decrease_in_COPD_PreRank_Bronch.csv", row.names = 1)
colnames(gsea_details2) <- gsub("\\.", "_", colnames(gsea_details2))
gsea_details2 <- merge(downBM, gsea_details2, by.x = "ensembl_gene_id", by.y = "ENSEMBL_GENEID")
gsea_details2 <- gsea_details2[order(gsea_details2$RANK_IN_GENE_LIST),]
gsea_details2 %>%
knitr::kable(
format = "html", align = rep("c", ncol(gsea_details2) + 1),
row.names = FALSE
) %>%
kableExtra::kable_styling() %>%
kableExtra::scroll_box(height = "300px")
| ensembl_gene_id | hgnc_symbol | RANK_IN_GENE_LIST | RANK_METRIC_SCORE | RUNNING_ES | CORE_ENRICHMENT |
|---|---|---|---|---|---|
| ENSG00000039537 | C6 | 2751 | 0.375 | -0.0328 | No |
| ENSG00000177300 | CLDN22 | 6204 | 0.239 | -0.1007 | No |
| ENSG00000185689 | C6orf201 | 6451 | 0.232 | -0.0807 | No |
| ENSG00000166396 | SERPINB7 | 7644 | 0.200 | -0.0906 | No |
| ENSG00000106772 | PRUNE2 | 9489 | 0.155 | -0.1237 | No |
| ENSG00000113448 | PDE4D | 14795 | 0.067 | -0.2626 | No |
| ENSG00000164265 | SCGB3A2 | 17090 | 0.040 | -0.3214 | No |
| ENSG00000170381 | SEMA3E | 19154 | 0.017 | -0.3764 | No |
| ENSG00000173376 | NDNF | 20197 | 0.007 | -0.4044 | No |
| ENSG00000048540 | LMO3 | 20319 | 0.005 | -0.4071 | No |
| ENSG00000170509 | HSD17B13 | 20415 | 0.004 | -0.4093 | No |
| ENSG00000154864 | PIEZO2 | 21873 | -0.011 | -0.4483 | No |
| ENSG00000186417 | GLDN | 24474 | -0.040 | -0.5156 | No |
| ENSG00000173988 | LRRC63 | 26469 | -0.065 | -0.5632 | No |
| ENSG00000133124 | IRS4 | 27358 | -0.078 | -0.5786 | No |
| ENSG00000145147 | SLIT2 | 28551 | -0.099 | -0.6001 | Yes |
| ENSG00000167315 | ACAA2 | 28815 | -0.105 | -0.5953 | Yes |
| ENSG00000012223 | LTF | 29206 | -0.113 | -0.5931 | Yes |
| ENSG00000069122 | ADGRF5 | 29524 | -0.121 | -0.5880 | Yes |
| ENSG00000149201 | CCDC81 | 29703 | -0.125 | -0.5785 | Yes |
| ENSG00000147231 | RADX | 30041 | -0.133 | -0.5725 | Yes |
| ENSG00000136205 | TNS3 | 30319 | -0.141 | -0.5640 | Yes |
| ENSG00000198721 | ECI2 | 30579 | -0.148 | -0.5541 | Yes |
| ENSG00000147570 | DNAJC5B | 31533 | -0.179 | -0.5403 | Yes |
| ENSG00000161298 | ZNF382 | 31621 | -0.182 | -0.5217 | Yes |
| ENSG00000134775 | FHOD3 | 32120 | -0.203 | -0.5121 | Yes |
| ENSG00000122420 | PTGFR | 32302 | -0.211 | -0.4927 | Yes |
| ENSG00000156076 | WIF1 | 32466 | -0.220 | -0.4719 | Yes |
| ENSG00000081479 | LRP2 | 32750 | -0.234 | -0.4527 | Yes |
| ENSG00000156284 | CLDN8 | 32791 | -0.237 | -0.4265 | Yes |
| ENSG00000103647 | CORO2B | 32820 | -0.238 | -0.3998 | Yes |
| ENSG00000134443 | GRP | 32921 | -0.243 | -0.3746 | Yes |
| ENSG00000197584 | KCNMB2 | 33108 | -0.254 | -0.3505 | Yes |
| ENSG00000163285 | GABRG1 | 33335 | -0.267 | -0.3259 | Yes |
| ENSG00000166148 | AVPR1A | 33537 | -0.282 | -0.2990 | Yes |
| ENSG00000206538 | VGLL3 | 33600 | -0.286 | -0.2677 | Yes |
| ENSG00000127990 | SGCE | 34198 | -0.332 | -0.2459 | Yes |
| ENSG00000038295 | TLL1 | 34371 | -0.349 | -0.2104 | Yes |
| ENSG00000242265 | PEG10 | 35044 | -0.432 | -0.1792 | Yes |
| ENSG00000079819 | EPB41L2 | 35057 | -0.434 | -0.1295 | Yes |
| ENSG00000113389 | NPR3 | 35084 | -0.436 | -0.0799 | Yes |
| ENSG00000096006 | CRISP3 | 35302 | -0.469 | -0.0318 | Yes |
| ENSG00000111341 | MGP | 35448 | -0.497 | 0.0215 | Yes |
## Uploading data to Enrichr... Done.
## Querying GO_Molecular_Function_2015... Done.
## Querying GO_Cellular_Component_2015... Done.
## Querying GO_Biological_Process_2015... Done.
## Parsing results... Done.
go_biological %>%
knitr::kable(
format = "html", align = rep("c", ncol(go_biological) + 1),
row.names = TRUE
) %>%
kableExtra::kable_styling() %>%
kableExtra::scroll_box(height = "300px")
| Term | Overlap | P.value | Adjusted.P.value | Old.P.value | Old.Adjusted.P.value | Odds.Ratio | Combined.Score | Genes | |
|---|---|---|---|---|---|---|---|---|---|
| 1 | positive regulation of phosphatidylinositol 3-kinase signaling (GO:0014068) | 5/51 | 0.0041953 | 1 | 0 | 0 | 4.6796762 | 25.6156174 | NTRK2;CSF3;ADORA3;WNT16;NKX3-1 |
| 2 | O-glycan processing (GO:0016266) | 5/56 | 0.0062667 | 1 | 0 | 0 | 4.2618479 | 21.6182668 | MUC1;B3GNT6;MUC3A;MUC5AC;MUC6 |
| 3 | regulation of phosphatidylinositol 3-kinase signaling (GO:0014066) | 5/66 | 0.0123812 | 1 | 0 | 0 | 3.6161134 | 15.8804244 | NTRK2;CSF3;ADORA3;WNT16;NKX3-1 |
| 4 | glucocorticoid biosynthetic process (GO:0006704) | 2/10 | 0.0176287 | 1 | 0 | 0 | 9.5465394 | 38.5510798 | HSD11B2;CYP17A1 |
| 5 | positive regulation of steroid hormone secretion (GO:2000833) | 2/11 | 0.0212509 | 1 | 0 | 0 | 8.6786722 | 33.4246616 | C1QTNF1;NKX3-1 |
| 6 | digestive system process (GO:0022600) | 4/51 | 0.0218884 | 1 | 0 | 0 | 3.7437409 | 14.3078149 | CHRM1;TFF1;ADRA2A;MUC6 |
| 7 | regulation of smooth muscle contraction (GO:0006940) | 4/51 | 0.0218884 | 1 | 0 | 0 | 3.7437409 | 14.3078149 | EDN2;TNNI3;PTGS2;ADRA2A |
| 8 | negative regulation of hydrogen peroxide-induced cell death (GO:1903206) | 2/12 | 0.0251521 | 1 | 0 | 0 | 7.9554495 | 29.2984249 | GPR37;PYCR1 |
| 9 | negative regulation of insulin secretion (GO:0046676) | 3/31 | 0.0265911 | 1 | 0 | 0 | 4.6192932 | 16.7549945 | BMP8A;ADRA2A;STXBP5L |
| 10 | negative regulation of response to reactive oxygen species (GO:1901032) | 2/13 | 0.0293193 | 1 | 0 | 0 | 7.3434918 | 25.9189276 | GPR37;PYCR1 |
| 11 | maintenance of gastrointestinal epithelium (GO:0030277) | 2/13 | 0.0293193 | 1 | 0 | 0 | 7.3434918 | 25.9189276 | TFF1;MUC6 |
| 12 | regulation of hydrogen peroxide-induced cell death (GO:1903205) | 2/13 | 0.0293193 | 1 | 0 | 0 | 7.3434918 | 25.9189276 | GPR37;PYCR1 |
| 13 | lipoxygenase pathway (GO:0019372) | 2/13 | 0.0293193 | 1 | 0 | 0 | 7.3434918 | 25.9189276 | PTGS2;ALOX15B |
| 14 | positive regulation of cell fate commitment (GO:0010455) | 2/13 | 0.0293193 | 1 | 0 | 0 | 7.3434918 | 25.9189276 | PAX6;SPDEF |
| 15 | positive regulation of transforming growth factor beta production (GO:0071636) | 2/13 | 0.0293193 | 1 | 0 | 0 | 7.3434918 | 25.9189276 | PTGS2;THBS1 |
| 16 | protein O-linked glycosylation (GO:0006493) | 5/83 | 0.0302483 | 1 | 0 | 0 | 2.8754637 | 10.0592761 | MUC1;B3GNT6;MUC3A;MUC5AC;MUC6 |
| 17 | female pregnancy (GO:0007565) | 5/85 | 0.0330527 | 1 | 0 | 0 | 2.8078057 | 9.5736393 | HSD11B2;MUC1;TFCP2L1;ADRA2A;PTHLH |
| 18 | prostaglandin biosynthetic process (GO:0001516) | 2/14 | 0.0337395 | 1 | 0 | 0 | 6.8189567 | 23.1100332 | EDN2;PTGS2 |
| 19 | negative regulation of smooth muscle contraction (GO:0045986) | 2/14 | 0.0337395 | 1 | 0 | 0 | 6.8189567 | 23.1100332 | PTGS2;ADRA2A |
| 20 | cartilage development involved in endochondral bone morphogenesis (GO:0060351) | 2/14 | 0.0337395 | 1 | 0 | 0 | 6.8189567 | 23.1100332 | COMP;THBS1 |
| 21 | prostanoid biosynthetic process (GO:0046457) | 2/14 | 0.0337395 | 1 | 0 | 0 | 6.8189567 | 23.1100332 | EDN2;PTGS2 |
| 22 | ossification (GO:0001503) | 6/116 | 0.0353823 | 1 | 0 | 0 | 2.4689326 | 8.2500448 | SLC26A2;AHSG;BMP8A;STC1;PTHLH;CTHRC1 |
| 23 | negative regulation of peptide hormone secretion (GO:0090278) | 3/35 | 0.0364310 | 1 | 0 | 0 | 4.0913740 | 13.5520062 | BMP8A;ADRA2A;STXBP5L |
| 24 | ovulation (GO:0030728) | 2/15 | 0.0384004 | 1 | 0 | 0 | 6.3643596 | 20.7458237 | PTGS2;CYP17A1 |
| 25 | positive regulation of macrophage derived foam cell differentiation (GO:0010744) | 2/15 | 0.0384004 | 1 | 0 | 0 | 6.3643596 | 20.7458237 | APOB;ALOX15B |
| 26 | negative regulation of interleukin-12 production (GO:0032695) | 2/15 | 0.0384004 | 1 | 0 | 0 | 6.3643596 | 20.7458237 | IRAK3;THBS1 |
| 27 | negative regulation of peptide secretion (GO:0002792) | 3/36 | 0.0391442 | 1 | 0 | 0 | 3.9777247 | 12.8898316 | BMP8A;ADRA2A;STXBP5L |
| 28 | epithelial cell maturation (GO:0002070) | 2/16 | 0.0432900 | 1 | 0 | 0 | 5.9665871 | 18.7340875 | SIX3;TFCP2L1 |
| 29 | negative regulation of anoikis (GO:2000811) | 2/16 | 0.0432900 | 1 | 0 | 0 | 5.9665871 | 18.7340875 | NTRK2;CEACAM5 |
| 30 | glucocorticoid metabolic process (GO:0008211) | 2/16 | 0.0432900 | 1 | 0 | 0 | 5.9665871 | 18.7340875 | HSD11B2;CYP17A1 |
| 31 | negative regulation of calcium ion transport (GO:0051926) | 3/38 | 0.0448688 | 1 | 0 | 0 | 3.7683708 | 11.6970666 | STC1;PTGS2;ADRA2A |
| 32 | regulation of steroid hormone secretion (GO:2000831) | 2/17 | 0.0483968 | 1 | 0 | 0 | 5.6156114 | 17.0058776 | C1QTNF1;NKX3-1 |
| 33 | purine ribonucleoside bisphosphate metabolic process (GO:0034035) | 2/17 | 0.0483968 | 1 | 0 | 0 | 5.6156114 | 17.0058776 | SULT1C2;SLC26A2 |
| 34 | 3’-phosphoadenosine 5’-phosphosulfate metabolic process (GO:0050427) | 2/17 | 0.0483968 | 1 | 0 | 0 | 5.6156114 | 17.0058776 | SULT1C2;SLC26A2 |
| 35 | epithelial structure maintenance (GO:0010669) | 2/17 | 0.0483968 | 1 | 0 | 0 | 5.6156114 | 17.0058776 | TFF1;MUC6 |
| 36 | decidualization (GO:0046697) | 2/18 | 0.0537095 | 1 | 0 | 0 | 5.3036330 | 15.5086983 | STC1;PTGS2 |
| 37 | inner ear receptor stereocilium organization (GO:0060122) | 2/18 | 0.0537095 | 1 | 0 | 0 | 5.3036330 | 15.5086983 | PCDH15;CTHRC1 |
| 38 | positive regulation of synaptic transmission, glutamatergic (GO:0051968) | 2/18 | 0.0537095 | 1 | 0 | 0 | 5.3036330 | 15.5086983 | NTRK2;PTGS2 |
| 39 | regulation of cAMP biosynthetic process (GO:0030817) | 5/98 | 0.0551609 | 1 | 0 | 0 | 2.4353417 | 7.0564042 | NTRK2;ADORA3;GRM8;ADRA2A;PTHLH |
| 40 | positive regulation of lipid transport (GO:0032370) | 3/44 | 0.0643482 | 1 | 0 | 0 | 3.2545021 | 8.9285531 | C1QTNF1;LIPG;NKX3-1 |
| 41 | glandular epithelial cell differentiation (GO:0002067) | 2/20 | 0.0649099 | 1 | 0 | 0 | 4.7732697 | 13.0537266 | PAX6;SPDEF |
| 42 | regulation of anoikis (GO:2000209) | 2/20 | 0.0649099 | 1 | 0 | 0 | 4.7732697 | 13.0537266 | NTRK2;CEACAM5 |
| 43 | negative regulation of muscle contraction (GO:0045932) | 2/20 | 0.0649099 | 1 | 0 | 0 | 4.7732697 | 13.0537266 | PTGS2;ADRA2A |
| 44 | hydrogen peroxide catabolic process (GO:0042744) | 2/20 | 0.0649099 | 1 | 0 | 0 | 4.7732697 | 13.0537266 | TPO;PXDN |
| 45 | cellular response to interleukin-1 (GO:0071347) | 3/45 | 0.0679171 | 1 | 0 | 0 | 3.1821798 | 8.5583702 | IRAK3;MYLK3;NKX3-1 |
| 46 | response to vitamin D (GO:0033280) | 2/21 | 0.0707769 | 1 | 0 | 0 | 4.5459711 | 12.0387430 | STC1;PTGS2 |
| 47 | cartilage development (GO:0051216) | 4/75 | 0.0724979 | 1 | 0 | 0 | 2.5457438 | 6.6805349 | COMP;ZBTB16;BMP8A;THBS1 |
| 48 | regulation of synaptic transmission, glutamatergic (GO:0051966) | 3/47 | 0.0753177 | 1 | 0 | 0 | 3.0467679 | 7.8790655 | NTRK2;GRM8;PTGS2 |
| 49 | regulation of transforming growth factor beta production (GO:0071634) | 2/22 | 0.0768087 | 1 | 0 | 0 | 4.3393361 | 11.1366327 | PTGS2;THBS1 |
| 50 | carbohydrate homeostasis (GO:0033500) | 6/143 | 0.0806388 | 1 | 0 | 0 | 2.0027705 | 5.0425256 | HKDC1;PAX6;BHLHA15;ADRA2A;FOXA3;STXBP5L |
| 51 | glucose homeostasis (GO:0042593) | 6/143 | 0.0806388 | 1 | 0 | 0 | 2.0027705 | 5.0425256 | HKDC1;PAX6;BHLHA15;ADRA2A;FOXA3;STXBP5L |
| 52 | positive regulation of leukocyte migration (GO:0002687) | 4/78 | 0.0811389 | 1 | 0 | 0 | 2.4478306 | 6.1479535 | CCL24;EDN2;ADORA3;THBS1 |
| 53 | regulation of response to reactive oxygen species (GO:1901031) | 2/23 | 0.0829959 | 1 | 0 | 0 | 4.1506693 | 10.3308677 | GPR37;PYCR1 |
| 54 | protein-lipid complex remodeling (GO:0034368) | 2/23 | 0.0829959 | 1 | 0 | 0 | 4.1506693 | 10.3308677 | LIPG;APOB |
| 55 | plasma lipoprotein particle remodeling (GO:0034369) | 2/23 | 0.0829959 | 1 | 0 | 0 | 4.1506693 | 10.3308677 | LIPG;APOB |
| 56 | endocrine process (GO:0050886) | 2/23 | 0.0829959 | 1 | 0 | 0 | 4.1506693 | 10.3308677 | HSD11B2;EDN2 |
| 57 | macromolecular complex remodeling (GO:0034367) | 2/23 | 0.0829959 | 1 | 0 | 0 | 4.1506693 | 10.3308677 | LIPG;APOB |
| 58 | regulation of systemic arterial blood pressure mediated by a chemical signal (GO:0003044) | 2/23 | 0.0829959 | 1 | 0 | 0 | 4.1506693 | 10.3308677 | HSD11B2;EDN2 |
| 59 | prostaglandin metabolic process (GO:0006693) | 2/23 | 0.0829959 | 1 | 0 | 0 | 4.1506693 | 10.3308677 | EDN2;PTGS2 |
| 60 | prostanoid metabolic process (GO:0006692) | 2/23 | 0.0829959 | 1 | 0 | 0 | 4.1506693 | 10.3308677 | EDN2;PTGS2 |
| 61 | positive regulation of blood vessel endothelial cell migration (GO:0043536) | 2/23 | 0.0829959 | 1 | 0 | 0 | 4.1506693 | 10.3308677 | PTGS2;THBS1 |
| 62 | regulation of systemic arterial blood pressure by hormone (GO:0001990) | 2/23 | 0.0829959 | 1 | 0 | 0 | 4.1506693 | 10.3308677 | HSD11B2;EDN2 |
| 63 | regulation of cAMP metabolic process (GO:0030814) | 5/113 | 0.0891193 | 1 | 0 | 0 | 2.1120662 | 5.1065095 | NTRK2;ADORA3;GRM8;ADRA2A;PTHLH |
| 64 | unsaturated fatty acid biosynthetic process (GO:0006636) | 3/51 | 0.0911233 | 1 | 0 | 0 | 2.8078057 | 6.7262158 | EDN2;PTGS2;ALOX15B |
| 65 | regulation of muscle contraction (GO:0006937) | 5/114 | 0.0916980 | 1 | 0 | 0 | 2.0935393 | 5.0019998 | EDN2;STC1;TNNI3;PTGS2;ADRA2A |
| 66 | regulation of vasoconstriction (GO:0019229) | 3/52 | 0.0952738 | 1 | 0 | 0 | 2.7538094 | 6.4742078 | EDN2;PTGS2;ADRA2A |
| 67 | columnar/cuboidal epithelial cell development (GO:0002066) | 2/25 | 0.0958000 | 1 | 0 | 0 | 3.8186158 | 8.9565341 | PAX6;SPDEF |
| 68 | positive regulation of smooth muscle contraction (GO:0045987) | 2/25 | 0.0958000 | 1 | 0 | 0 | 3.8186158 | 8.9565341 | EDN2;PTGS2 |
| 69 | response to testosterone (GO:0033574) | 2/25 | 0.0958000 | 1 | 0 | 0 | 3.8186158 | 8.9565341 | THBS1;NKX3-1 |
| 70 | regulation of lipid transport (GO:0032368) | 4/83 | 0.0966088 | 1 | 0 | 0 | 2.3003709 | 5.3761630 | C1QTNF1;LIPG;THBS1;NKX3-1 |
| 71 | regulation of cyclic nucleotide biosynthetic process (GO:0030802) | 5/116 | 0.0969693 | 1 | 0 | 0 | 2.0574438 | 4.8007583 | NTRK2;ADORA3;GRM8;ADRA2A;PTHLH |
| 72 | keratinocyte differentiation (GO:0030216) | 3/54 | 0.1038009 | 1 | 0 | 0 | 2.6518165 | 6.0071090 | CDSN;PAX6;WNT16 |
| 73 | regulation of purine nucleotide biosynthetic process (GO:1900371) | 5/119 | 0.1051573 | 1 | 0 | 0 | 2.0055755 | 4.5171533 | NTRK2;ADORA3;GRM8;ADRA2A;PTHLH |
| 74 | regulation of nucleotide biosynthetic process (GO:0030808) | 5/119 | 0.1051573 | 1 | 0 | 0 | 2.0055755 | 4.5171533 | NTRK2;ADORA3;GRM8;ADRA2A;PTHLH |
| 75 | multi-multicellular organism process (GO:0044706) | 5/121 | 0.1107996 | 1 | 0 | 0 | 1.9724255 | 4.3394001 | HSD11B2;MUC1;TFCP2L1;ADRA2A;PTHLH |
| 76 | adenylate cyclase-modulating G-protein coupled receptor signaling pathway (GO:0007188) | 5/122 | 0.1136747 | 1 | 0 | 0 | 1.9562581 | 4.2537152 | GPR37;ADM2;GRM8;ADRA2A;PTHLH |
| 77 | negative regulation of oxidative stress-induced cell death (GO:1903202) | 2/28 | 0.1159532 | 1 | 0 | 0 | 3.4094783 | 7.3459547 | GPR37;PYCR1 |
| 78 | regulation of neuroblast proliferation (GO:1902692) | 2/28 | 0.1159532 | 1 | 0 | 0 | 3.4094783 | 7.3459547 | SIX3;PAX6 |
| 79 | regulation of macrophage derived foam cell differentiation (GO:0010743) | 2/28 | 0.1159532 | 1 | 0 | 0 | 3.4094783 | 7.3459547 | APOB;ALOX15B |
| 80 | negative regulation of hormone secretion (GO:0046888) | 3/57 | 0.1171287 | 1 | 0 | 0 | 2.5122472 | 5.3874682 | BMP8A;ADRA2A;STXBP5L |
| 81 | positive regulation of actin filament polymerization (GO:0030838) | 3/57 | 0.1171287 | 1 | 0 | 0 | 2.5122472 | 5.3874682 | CCL24;CSF3;CDC42EP5 |
| 82 | negative regulation of response to oxidative stress (GO:1902883) | 2/29 | 0.1228915 | 1 | 0 | 0 | 3.2919101 | 6.9013369 | GPR37;PYCR1 |
| 83 | negative regulation of cellular response to oxidative stress (GO:1900408) | 2/29 | 0.1228915 | 1 | 0 | 0 | 3.2919101 | 6.9013369 | GPR37;PYCR1 |
| 84 | regulation of systemic arterial blood pressure (GO:0003073) | 2/29 | 0.1228915 | 1 | 0 | 0 | 3.2919101 | 6.9013369 | HSD11B2;EDN2 |
| 85 | pituitary gland development (GO:0021983) | 2/29 | 0.1228915 | 1 | 0 | 0 | 3.2919101 | 6.9013369 | SIX3;PAX6 |
| 86 | lens development in camera-type eye (GO:0002088) | 2/30 | 0.1299275 | 1 | 0 | 0 | 3.1821798 | 6.4941249 | SIX3;PAX6 |
| 87 | regulation of membrane lipid distribution (GO:0097035) | 2/30 | 0.1299275 | 1 | 0 | 0 | 3.1821798 | 6.4941249 | ATP10B;ANO7 |
| 88 | regulation of cell fate commitment (GO:0010453) | 2/30 | 0.1299275 | 1 | 0 | 0 | 3.1821798 | 6.4941249 | PAX6;SPDEF |
| 89 | negative regulation of ion transport (GO:0043271) | 4/94 | 0.1349839 | 1 | 0 | 0 | 2.0311786 | 4.0676380 | STC1;PTGS2;THBS1;ADRA2A |
| 90 | negative regulation of endothelial cell migration (GO:0010596) | 2/31 | 0.1370541 | 1 | 0 | 0 | 3.0795288 | 6.1201917 | STC1;THBS1 |
| 91 | positive regulation of muscle contraction (GO:0045933) | 2/31 | 0.1370541 | 1 | 0 | 0 | 3.0795288 | 6.1201917 | EDN2;PTGS2 |
| 92 | plasma lipoprotein particle organization (GO:0071827) | 2/31 | 0.1370541 | 1 | 0 | 0 | 3.0795288 | 6.1201917 | LIPG;APOB |
| 93 | positive regulation of response to wounding (GO:1903036) | 5/130 | 0.1379232 | 1 | 0 | 0 | 1.8358730 | 3.6369716 | CCL24;ADORA3;PTGS2;THBS1;ADRA2A |
| 94 | adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway (GO:0007193) | 3/62 | 0.1406464 | 1 | 0 | 0 | 2.3096466 | 4.5303865 | GPR37;GRM8;ADRA2A |
| 95 | regulation of adenylate cyclase activity (GO:0045761) | 3/62 | 0.1406464 | 1 | 0 | 0 | 2.3096466 | 4.5303865 | NTRK2;ADORA3;ADRA2A |
| 96 | eye photoreceptor cell development (GO:0042462) | 2/32 | 0.1442646 | 1 | 0 | 0 | 2.9832936 | 5.7759738 | NTRK2;PAX6 |
| 97 | activation of adenylate cyclase activity (GO:0007190) | 2/32 | 0.1442646 | 1 | 0 | 0 | 2.9832936 | 5.7759738 | NTRK2;ADORA3 |
| 98 | negative regulation of cytokine-mediated signaling pathway (GO:0001960) | 2/32 | 0.1442646 | 1 | 0 | 0 | 2.9832936 | 5.7759738 | PXDN;IRAK3 |
| 99 | negative regulation of cAMP biosynthetic process (GO:0030818) | 2/32 | 0.1442646 | 1 | 0 | 0 | 2.9832936 | 5.7759738 | GRM8;ADRA2A |
| 100 | response to purine-containing compound (GO:0014074) | 5/132 | 0.1443166 | 1 | 0 | 0 | 1.8080567 | 3.4999387 | STC1;PLAT;SLC6A1;PTGS2;CYP17A1 |
| 101 | regulation of cyclic nucleotide metabolic process (GO:0030799) | 5/133 | 0.1475605 | 1 | 0 | 0 | 1.7944623 | 3.4337340 | NTRK2;ADORA3;GRM8;ADRA2A;PTHLH |
| 102 | negative regulation of cyclic nucleotide biosynthetic process (GO:0030803) | 2/33 | 0.1515521 | 1 | 0 | 0 | 2.8928907 | 5.4583800 | GRM8;ADRA2A |
| 103 | hydrogen peroxide metabolic process (GO:0042743) | 2/33 | 0.1515521 | 1 | 0 | 0 | 2.8928907 | 5.4583800 | TPO;PXDN |
| 104 | protein-lipid complex subunit organization (GO:0071825) | 2/33 | 0.1515521 | 1 | 0 | 0 | 2.8928907 | 5.4583800 | LIPG;APOB |
| 105 | positive regulation of cAMP biosynthetic process (GO:0030819) | 3/65 | 0.1554543 | 1 | 0 | 0 | 2.2030475 | 4.1007610 | NTRK2;ADORA3;PTHLH |
| 106 | bone trabecula formation (GO:0060346) | 1/8 | 0.1558373 | 1 | 0 | 0 | 5.9665871 | 11.0915436 | FBN2 |
| 107 | negative regulation of calcium ion-dependent exocytosis (GO:0045955) | 1/8 | 0.1558373 | 1 | 0 | 0 | 5.9665871 | 11.0915436 | ADRA2A |
| 108 | short-term memory (GO:0007614) | 1/8 | 0.1558373 | 1 | 0 | 0 | 5.9665871 | 11.0915436 | CUX2 |
| 109 | energy homeostasis (GO:0097009) | 1/8 | 0.1558373 | 1 | 0 | 0 | 5.9665871 | 11.0915436 | EDN2 |
| 110 | positive regulation of heat generation (GO:0031652) | 1/8 | 0.1558373 | 1 | 0 | 0 | 5.9665871 | 11.0915436 | PTGS2 |
| 111 | nucleoside diphosphate catabolic process (GO:0009134) | 1/8 | 0.1558373 | 1 | 0 | 0 | 5.9665871 | 11.0915436 | ENTPD2 |
| 112 | positive regulation of fibroblast migration (GO:0010763) | 1/8 | 0.1558373 | 1 | 0 | 0 | 5.9665871 | 11.0915436 | THBS1 |
| 113 | regulation of dendritic cell antigen processing and presentation (GO:0002604) | 1/8 | 0.1558373 | 1 | 0 | 0 | 5.9665871 | 11.0915436 | THBS1 |
| 114 | proline biosynthetic process (GO:0006561) | 1/8 | 0.1558373 | 1 | 0 | 0 | 5.9665871 | 11.0915436 | PYCR1 |
| 115 | regulation of fever generation (GO:0031620) | 1/8 | 0.1558373 | 1 | 0 | 0 | 5.9665871 | 11.0915436 | PTGS2 |
| 116 | regulation of sarcomere organization (GO:0060297) | 1/8 | 0.1558373 | 1 | 0 | 0 | 5.9665871 | 11.0915436 | MYLK3 |
| 117 | C4-dicarboxylate transport (GO:0015740) | 1/8 | 0.1558373 | 1 | 0 | 0 | 5.9665871 | 11.0915436 | SLC13A5 |
| 118 | cornea development in camera-type eye (GO:0061303) | 1/8 | 0.1558373 | 1 | 0 | 0 | 5.9665871 | 11.0915436 | PAX6 |
| 119 | very-low-density lipoprotein particle assembly (GO:0034379) | 1/8 | 0.1558373 | 1 | 0 | 0 | 5.9665871 | 11.0915436 | APOB |
| 120 | sequestering of extracellular ligand from receptor (GO:0035581) | 1/8 | 0.1558373 | 1 | 0 | 0 | 5.9665871 | 11.0915436 | FBN2 |
| 121 | artery smooth muscle contraction (GO:0014824) | 1/8 | 0.1558373 | 1 | 0 | 0 | 5.9665871 | 11.0915436 | EDN2 |
| 122 | response to methylmercury (GO:0051597) | 1/8 | 0.1558373 | 1 | 0 | 0 | 5.9665871 | 11.0915436 | CYP17A1 |
| 123 | regulation of transforming growth factor beta1 production (GO:0032908) | 1/8 | 0.1558373 | 1 | 0 | 0 | 5.9665871 | 11.0915436 | THBS1 |
| 124 | neurological system process involved in regulation of systemic arterial blood pressure (GO:0001976) | 1/8 | 0.1558373 | 1 | 0 | 0 | 5.9665871 | 11.0915436 | TNNI3 |
| 125 | positive regulation of vesicle fusion (GO:0031340) | 1/8 | 0.1558373 | 1 | 0 | 0 | 5.9665871 | 11.0915436 | DOC2B |
| 126 | skin morphogenesis (GO:0043589) | 1/8 | 0.1558373 | 1 | 0 | 0 | 5.9665871 | 11.0915436 | CDSN |
| 127 | chondrocyte proliferation (GO:0035988) | 1/8 | 0.1558373 | 1 | 0 | 0 | 5.9665871 | 11.0915436 | STC1 |
| 128 | positive regulation of ryanodine-sensitive calcium-release channel activity (GO:0060316) | 1/8 | 0.1558373 | 1 | 0 | 0 | 5.9665871 | 11.0915436 | JPH2 |
| 129 | negative regulation of fatty acid transport (GO:2000192) | 1/8 | 0.1558373 | 1 | 0 | 0 | 5.9665871 | 11.0915436 | THBS1 |
| 130 | righting reflex (GO:0060013) | 1/8 | 0.1558373 | 1 | 0 | 0 | 5.9665871 | 11.0915436 | PCDH15 |
| 131 | positive regulation of chemokine secretion (GO:0090197) | 1/8 | 0.1558373 | 1 | 0 | 0 | 5.9665871 | 11.0915436 | ALOX15B |
| 132 | receptor recycling (GO:0001881) | 1/8 | 0.1558373 | 1 | 0 | 0 | 5.9665871 | 11.0915436 | REP15 |
| 133 | cellular response to ATP (GO:0071318) | 1/8 | 0.1558373 | 1 | 0 | 0 | 5.9665871 | 11.0915436 | PTGS2 |
| 134 | histamine secretion (GO:0001821) | 1/8 | 0.1558373 | 1 | 0 | 0 | 5.9665871 | 11.0915436 | ADORA3 |
| 135 | intestinal epithelial cell development (GO:0060576) | 1/8 | 0.1558373 | 1 | 0 | 0 | 5.9665871 | 11.0915436 | SPDEF |
| 136 | positive regulation of dendritic spine morphogenesis (GO:0061003) | 1/8 | 0.1558373 | 1 | 0 | 0 | 5.9665871 | 11.0915436 | CUX2 |
| 137 | negative regulation of norepinephrine secretion (GO:0010700) | 1/8 | 0.1558373 | 1 | 0 | 0 | 5.9665871 | 11.0915436 | ADRA2A |
| 138 | low-density lipoprotein particle clearance (GO:0034383) | 1/8 | 0.1558373 | 1 | 0 | 0 | 5.9665871 | 11.0915436 | APOB |
| 139 | negative regulation of synaptic transmission, GABAergic (GO:0032229) | 1/8 | 0.1558373 | 1 | 0 | 0 | 5.9665871 | 11.0915436 | SLC6A1 |
| 140 | photoreceptor cell development (GO:0042461) | 2/34 | 0.1589105 | 1 | 0 | 0 | 2.8078057 | 5.1647173 | NTRK2;PAX6 |
| 141 | regulation of calcium ion-dependent exocytosis (GO:0017158) | 2/34 | 0.1589105 | 1 | 0 | 0 | 2.8078057 | 5.1647173 | DOC2B;ADRA2A |
| 142 | positive regulation of angiogenesis (GO:0045766) | 4/101 | 0.1621454 | 1 | 0 | 0 | 1.8904038 | 3.4391397 | CCL24;ADM2;PTGS2;THBS1 |
| 143 | negative regulation of purine nucleotide biosynthetic process (GO:1900372) | 2/35 | 0.1663335 | 1 | 0 | 0 | 2.7275827 | 4.8926297 | GRM8;ADRA2A |
| 144 | nucleoside bisphosphate metabolic process (GO:0033865) | 2/35 | 0.1663335 | 1 | 0 | 0 | 2.7275827 | 4.8926297 | SULT1C2;SLC26A2 |
| 145 | regulation of endocrine process (GO:0044060) | 2/35 | 0.1663335 | 1 | 0 | 0 | 2.7275827 | 4.8926297 | C1QTNF1;NKX3-1 |
| 146 | ribonucleoside bisphosphate metabolic process (GO:0033875) | 2/35 | 0.1663335 | 1 | 0 | 0 | 2.7275827 | 4.8926297 | SULT1C2;SLC26A2 |
| 147 | purine nucleoside bisphosphate metabolic process (GO:0034032) | 2/35 | 0.1663335 | 1 | 0 | 0 | 2.7275827 | 4.8926297 | SULT1C2;SLC26A2 |
| 148 | negative regulation of nucleotide biosynthetic process (GO:0030809) | 2/35 | 0.1663335 | 1 | 0 | 0 | 2.7275827 | 4.8926297 | GRM8;ADRA2A |
| 149 | multi-organism reproductive process (GO:0044703) | 5/140 | 0.1711062 | 1 | 0 | 0 | 1.7047392 | 3.0096678 | HSD11B2;MUC1;TFCP2L1;ADRA2A;PTHLH |
| 150 | gamma-aminobutyric acid transport (GO:0015812) | 1/9 | 0.1735296 | 1 | 0 | 0 | 5.3036330 | 9.2888214 | SLC6A1 |
| 151 | positive regulation of tolerance induction (GO:0002645) | 1/9 | 0.1735296 | 1 | 0 | 0 | 5.3036330 | 9.2888214 | IRAK3 |
| 152 | fucose catabolic process (GO:0019317) | 1/9 | 0.1735296 | 1 | 0 | 0 | 5.3036330 | 9.2888214 | FUT6 |
| 153 | alkaloid metabolic process (GO:0009820) | 1/9 | 0.1735296 | 1 | 0 | 0 | 5.3036330 | 9.2888214 | CYP3A5 |
| 154 | L-fucose metabolic process (GO:0042354) | 1/9 | 0.1735296 | 1 | 0 | 0 | 5.3036330 | 9.2888214 | FUT6 |
| 155 | positive regulation of hormone biosynthetic process (GO:0046886) | 1/9 | 0.1735296 | 1 | 0 | 0 | 5.3036330 | 9.2888214 | CYP17A1 |
| 156 | positive regulation of osteoblast proliferation (GO:0033690) | 1/9 | 0.1735296 | 1 | 0 | 0 | 5.3036330 | 9.2888214 | CTHRC1 |
| 157 | mitochondrial calcium ion transport (GO:0006851) | 1/9 | 0.1735296 | 1 | 0 | 0 | 5.3036330 | 9.2888214 | BHLHA15 |
| 158 | tonic smooth muscle contraction (GO:0014820) | 1/9 | 0.1735296 | 1 | 0 | 0 | 5.3036330 | 9.2888214 | EDN2 |
| 159 | artery development (GO:0060840) | 1/9 | 0.1735296 | 1 | 0 | 0 | 5.3036330 | 9.2888214 | NKX3-1 |
| 160 | endocardial cushion development (GO:0003197) | 1/9 | 0.1735296 | 1 | 0 | 0 | 5.3036330 | 9.2888214 | THBS1 |
| 161 | adenosine receptor signaling pathway (GO:0001973) | 1/9 | 0.1735296 | 1 | 0 | 0 | 5.3036330 | 9.2888214 | ADORA3 |
| 162 | L-fucose catabolic process (GO:0042355) | 1/9 | 0.1735296 | 1 | 0 | 0 | 5.3036330 | 9.2888214 | FUT6 |
| 163 | positive regulation of amino acid transport (GO:0051957) | 1/9 | 0.1735296 | 1 | 0 | 0 | 5.3036330 | 9.2888214 | SLC6A1 |
| 164 | eosinophil chemotaxis (GO:0048245) | 1/9 | 0.1735296 | 1 | 0 | 0 | 5.3036330 | 9.2888214 | CCL24 |
| 165 | regulation of chemokine secretion (GO:0090196) | 1/9 | 0.1735296 | 1 | 0 | 0 | 5.3036330 | 9.2888214 | ALOX15B |
| 166 | glucose 6-phosphate metabolic process (GO:0051156) | 1/9 | 0.1735296 | 1 | 0 | 0 | 5.3036330 | 9.2888214 | HKDC1 |
| 167 | negative regulation of homotypic cell-cell adhesion (GO:0034111) | 1/9 | 0.1735296 | 1 | 0 | 0 | 5.3036330 | 9.2888214 | C1QTNF1 |
| 168 | positive regulation of mast cell degranulation (GO:0043306) | 1/9 | 0.1735296 | 1 | 0 | 0 | 5.3036330 | 9.2888214 | ADORA3 |
| 169 | positive regulation of mast cell activation involved in immune response (GO:0033008) | 1/9 | 0.1735296 | 1 | 0 | 0 | 5.3036330 | 9.2888214 | ADORA3 |
| 170 | retinal rod cell development (GO:0046548) | 1/9 | 0.1735296 | 1 | 0 | 0 | 5.3036330 | 9.2888214 | NTRK2 |
| 171 | positive regulation of transcription factor import into nucleus (GO:0042993) | 2/36 | 0.1738152 | 1 | 0 | 0 | 2.6518165 | 4.6400487 | CSF3;PTGS2 |
| 172 | negative regulation of cAMP metabolic process (GO:0030815) | 2/36 | 0.1738152 | 1 | 0 | 0 | 2.6518165 | 4.6400487 | GRM8;ADRA2A |
| 173 | negative regulation of response to cytokine stimulus (GO:0060761) | 2/36 | 0.1738152 | 1 | 0 | 0 | 2.6518165 | 4.6400487 | PXDN;IRAK3 |
| 174 | positive regulation of protein polymerization (GO:0032273) | 3/69 | 0.1759027 | 1 | 0 | 0 | 2.0753346 | 3.6065664 | CCL24;CSF3;CDC42EP5 |
| 175 | negative regulation of cyclic nucleotide metabolic process (GO:0030800) | 2/37 | 0.1813500 | 1 | 0 | 0 | 2.5801458 | 4.4051511 | GRM8;ADRA2A |
| 176 | positive regulation of adenylate cyclase activity (GO:0045762) | 2/37 | 0.1813500 | 1 | 0 | 0 | 2.5801458 | 4.4051511 | NTRK2;ADORA3 |
| 177 | regulation of muscle system process (GO:0090257) | 5/144 | 0.1851754 | 1 | 0 | 0 | 1.6573853 | 2.7951006 | EDN2;STC1;TNNI3;PTGS2;ADRA2A |
| 178 | response to interleukin-1 (GO:0070555) | 3/71 | 0.1863944 | 1 | 0 | 0 | 2.0168745 | 3.3881279 | IRAK3;MYLK3;NKX3-1 |
| 179 | regulation of wound healing (GO:0061041) | 4/107 | 0.1868587 | 1 | 0 | 0 | 1.7843999 | 2.9931571 | C1QTNF1;PLAT;THBS1;ADRA2A |
| 180 | positive regulation of fat cell differentiation (GO:0045600) | 2/38 | 0.1889323 | 1 | 0 | 0 | 2.5122472 | 4.1863248 | ZBTB16;PTGS2 |
| 181 | lung alveolus development (GO:0048286) | 2/38 | 0.1889323 | 1 | 0 | 0 | 2.5122472 | 4.1863248 | EDN2;PTHLH |
| 182 | phospholipid scrambling (GO:0017121) | 1/10 | 0.1908519 | 1 | 0 | 0 | 4.7732697 | 7.9057641 | ANO7 |
| 183 | regulation of heat generation (GO:0031650) | 1/10 | 0.1908519 | 1 | 0 | 0 | 4.7732697 | 7.9057641 | PTGS2 |
| 184 | nucleoside diphosphate biosynthetic process (GO:0009133) | 1/10 | 0.1908519 | 1 | 0 | 0 | 4.7732697 | 7.9057641 | ENTPD8 |
| 185 | regulation of uterine smooth muscle contraction (GO:0070472) | 1/10 | 0.1908519 | 1 | 0 | 0 | 4.7732697 | 7.9057641 | ADRA2A |
| 186 | regulation of macrophage chemotaxis (GO:0010758) | 1/10 | 0.1908519 | 1 | 0 | 0 | 4.7732697 | 7.9057641 | THBS1 |
| 187 | auditory receptor cell stereocilium organization (GO:0060088) | 1/10 | 0.1908519 | 1 | 0 | 0 | 4.7732697 | 7.9057641 | PCDH15 |
| 188 | positive regulation of tumor necrosis factor biosynthetic process (GO:0042535) | 1/10 | 0.1908519 | 1 | 0 | 0 | 4.7732697 | 7.9057641 | THBS1 |
| 189 | surfactant homeostasis (GO:0043129) | 1/10 | 0.1908519 | 1 | 0 | 0 | 4.7732697 | 7.9057641 | PTHLH |
| 190 | positive regulation of pseudopodium assembly (GO:0031274) | 1/10 | 0.1908519 | 1 | 0 | 0 | 4.7732697 | 7.9057641 | CDC42EP5 |
| 191 | coenzyme catabolic process (GO:0009109) | 1/10 | 0.1908519 | 1 | 0 | 0 | 4.7732697 | 7.9057641 | ALDH1L2 |
| 192 | heart contraction (GO:0060047) | 1/10 | 0.1908519 | 1 | 0 | 0 | 4.7732697 | 7.9057641 | TNNI3 |
| 193 | cardiac left ventricle morphogenesis (GO:0003214) | 1/10 | 0.1908519 | 1 | 0 | 0 | 4.7732697 | 7.9057641 | CPE |
| 194 | eosinophil migration (GO:0072677) | 1/10 | 0.1908519 | 1 | 0 | 0 | 4.7732697 | 7.9057641 | CCL24 |
| 195 | regulation of plasminogen activation (GO:0010755) | 1/10 | 0.1908519 | 1 | 0 | 0 | 4.7732697 | 7.9057641 | THBS1 |
| 196 | long-chain fatty acid biosynthetic process (GO:0042759) | 1/10 | 0.1908519 | 1 | 0 | 0 | 4.7732697 | 7.9057641 | ALOX15B |
| 197 | negative regulation of transcription by competitive promoter binding (GO:0010944) | 1/10 | 0.1908519 | 1 | 0 | 0 | 4.7732697 | 7.9057641 | MUC1 |
| 198 | positive regulation of macrophage activation (GO:0043032) | 1/10 | 0.1908519 | 1 | 0 | 0 | 4.7732697 | 7.9057641 | THBS1 |
| 199 | positive regulation of keratinocyte differentiation (GO:0045618) | 1/10 | 0.1908519 | 1 | 0 | 0 | 4.7732697 | 7.9057641 | ALOX15B |
| 200 | mitochondrion distribution (GO:0048311) | 1/10 | 0.1908519 | 1 | 0 | 0 | 4.7732697 | 7.9057641 | BHLHA15 |
| 201 | regulation of epithelial cell proliferation involved in prostate gland development (GO:0060768) | 1/10 | 0.1908519 | 1 | 0 | 0 | 4.7732697 | 7.9057641 | NKX3-1 |
| 202 | phospholipid homeostasis (GO:0055091) | 1/10 | 0.1908519 | 1 | 0 | 0 | 4.7732697 | 7.9057641 | LIPG |
| 203 | response to insecticide (GO:0017085) | 1/10 | 0.1908519 | 1 | 0 | 0 | 4.7732697 | 7.9057641 | CYP17A1 |
| 204 | histamine transport (GO:0051608) | 1/10 | 0.1908519 | 1 | 0 | 0 | 4.7732697 | 7.9057641 | ADORA3 |
| 205 | negative regulation of fibrinolysis (GO:0051918) | 1/10 | 0.1908519 | 1 | 0 | 0 | 4.7732697 | 7.9057641 | THBS1 |
| 206 | peripheral nervous system neuron development (GO:0048935) | 1/10 | 0.1908519 | 1 | 0 | 0 | 4.7732697 | 7.9057641 | NTRK2 |
| 207 | heart process (GO:0003015) | 1/10 | 0.1908519 | 1 | 0 | 0 | 4.7732697 | 7.9057641 | TNNI3 |
| 208 | positive regulation of transcription from RNA polymerase II promoter in response to stress (GO:0036003) | 1/10 | 0.1908519 | 1 | 0 | 0 | 4.7732697 | 7.9057641 | MUC1 |
| 209 | regulation of mononuclear cell migration (GO:0071675) | 1/10 | 0.1908519 | 1 | 0 | 0 | 4.7732697 | 7.9057641 | THBS1 |
| 210 | positive regulation of blood circulation (GO:1903524) | 3/72 | 0.1917005 | 1 | 0 | 0 | 1.9888624 | 3.2852446 | EDN2;PTGS2;ADRA2A |
| 211 | negative regulation of purine nucleotide metabolic process (GO:1900543) | 3/72 | 0.1917005 | 1 | 0 | 0 | 1.9888624 | 3.2852446 | GRM8;TNNI3;ADRA2A |
| 212 | positive regulation of cAMP metabolic process (GO:0030816) | 3/72 | 0.1917005 | 1 | 0 | 0 | 1.9888624 | 3.2852446 | NTRK2;ADORA3;PTHLH |
| 213 | nucleoside diphosphate metabolic process (GO:0009132) | 2/39 | 0.1965568 | 1 | 0 | 0 | 2.4478306 | 3.9821398 | ENTPD2;ENTPD8 |
| 214 | embryo implantation (GO:0007566) | 2/39 | 0.1965568 | 1 | 0 | 0 | 2.4478306 | 3.9821398 | STC1;PTGS2 |
| 215 | regulation of oxidative stress-induced cell death (GO:1903201) | 2/39 | 0.1965568 | 1 | 0 | 0 | 2.4478306 | 3.9821398 | GPR37;PYCR1 |
| 216 | regulation of cyclase activity (GO:0031279) | 3/73 | 0.1970443 | 1 | 0 | 0 | 1.9616177 | 3.1863084 | NTRK2;ADORA3;ADRA2A |
| 217 | regulation of leukocyte migration (GO:0002685) | 4/110 | 0.1996464 | 1 | 0 | 0 | 1.7357344 | 2.7966286 | CCL24;EDN2;ADORA3;THBS1 |
| 218 | response to tumor necrosis factor (GO:0034612) | 4/111 | 0.2039667 | 1 | 0 | 0 | 1.7200972 | 2.7346080 | APOB;PTGS2;THBS1;NKX3-1 |
| 219 | bone development (GO:0060348) | 2/40 | 0.2042185 | 1 | 0 | 0 | 2.3866348 | 3.7913235 | CHAD;STC1 |
| 220 | anterior/posterior pattern specification (GO:0009952) | 5/150 | 0.2070286 | 1 | 0 | 0 | 1.5910899 | 2.5058047 | ZBTB16;SIX3;PAX6;FEZF1;NKX3-1 |
| 221 | regulation of peroxisome proliferator activated receptor signaling pathway (GO:0035358) | 1/11 | 0.2078120 | 1 | 0 | 0 | 4.3393361 | 6.8176239 | ALOX15B |
| 222 | proline metabolic process (GO:0006560) | 1/11 | 0.2078120 | 1 | 0 | 0 | 4.3393361 | 6.8176239 | PYCR1 |
| 223 | regulation of pseudopodium assembly (GO:0031272) | 1/11 | 0.2078120 | 1 | 0 | 0 | 4.3393361 | 6.8176239 | CDC42EP5 |
| 224 | positive regulation of endothelial cell apoptotic process (GO:2000353) | 1/11 | 0.2078120 | 1 | 0 | 0 | 4.3393361 | 6.8176239 | THBS1 |
| 225 | low-density lipoprotein particle remodeling (GO:0034374) | 1/11 | 0.2078120 | 1 | 0 | 0 | 4.3393361 | 6.8176239 | APOB |
| 226 | regulation of cardiac muscle cell contraction (GO:0086004) | 1/11 | 0.2078120 | 1 | 0 | 0 | 4.3393361 | 6.8176239 | STC1 |
| 227 | dopamine biosynthetic process (GO:0042416) | 1/11 | 0.2078120 | 1 | 0 | 0 | 4.3393361 | 6.8176239 | GPR37 |
| 228 | mitotic cell cycle arrest (GO:0071850) | 1/11 | 0.2078120 | 1 | 0 | 0 | 4.3393361 | 6.8176239 | NKX3-1 |
| 229 | response to lead ion (GO:0010288) | 1/11 | 0.2078120 | 1 | 0 | 0 | 4.3393361 | 6.8176239 | SLC6A1 |
| 230 | replicative senescence (GO:0090399) | 1/11 | 0.2078120 | 1 | 0 | 0 | 4.3393361 | 6.8176239 | WNT16 |
| 231 | pinocytosis (GO:0006907) | 1/11 | 0.2078120 | 1 | 0 | 0 | 4.3393361 | 6.8176239 | AHSG |
| 232 | oxidative demethylation (GO:0070989) | 1/11 | 0.2078120 | 1 | 0 | 0 | 4.3393361 | 6.8176239 | CYP3A5 |
| 233 | positive regulation of epidermal growth factor-activated receptor activity (GO:0045741) | 1/11 | 0.2078120 | 1 | 0 | 0 | 4.3393361 | 6.8176239 | ADRA2A |
| 234 | basement membrane organization (GO:0071711) | 1/11 | 0.2078120 | 1 | 0 | 0 | 4.3393361 | 6.8176239 | NID2 |
| 235 | cellular response to prostaglandin stimulus (GO:0071379) | 1/11 | 0.2078120 | 1 | 0 | 0 | 4.3393361 | 6.8176239 | APOB |
| 236 | regulation of energy homeostasis (GO:2000505) | 1/11 | 0.2078120 | 1 | 0 | 0 | 4.3393361 | 6.8176239 | BMP8A |
| 237 | negative regulation of focal adhesion assembly (GO:0051895) | 1/11 | 0.2078120 | 1 | 0 | 0 | 4.3393361 | 6.8176239 | THBS1 |
| 238 | regulation of timing of cell differentiation (GO:0048505) | 1/11 | 0.2078120 | 1 | 0 | 0 | 4.3393361 | 6.8176239 | PAX6 |
| 239 | negative regulation of adherens junction organization (GO:1903392) | 1/11 | 0.2078120 | 1 | 0 | 0 | 4.3393361 | 6.8176239 | THBS1 |
| 240 | negative regulation of cell junction assembly (GO:1901889) | 1/11 | 0.2078120 | 1 | 0 | 0 | 4.3393361 | 6.8176239 | THBS1 |
| 241 | response to peptidoglycan (GO:0032494) | 1/11 | 0.2078120 | 1 | 0 | 0 | 4.3393361 | 6.8176239 | IRAK3 |
| 242 | negative regulation of myotube differentiation (GO:0010832) | 1/11 | 0.2078120 | 1 | 0 | 0 | 4.3393361 | 6.8176239 | CEACAM5 |
| 243 | regulation of lipoprotein metabolic process (GO:0050746) | 1/11 | 0.2078120 | 1 | 0 | 0 | 4.3393361 | 6.8176239 | LIPG |
| 244 | protein heterotrimerization (GO:0070208) | 1/11 | 0.2078120 | 1 | 0 | 0 | 4.3393361 | 6.8176239 | C1QTNF1 |
| 245 | negative regulation of nucleotide metabolic process (GO:0045980) | 3/75 | 0.2078374 | 1 | 0 | 0 | 1.9093079 | 2.9995211 | GRM8;TNNI3;ADRA2A |
| 246 | regulation of exocytosis (GO:0017157) | 4/112 | 0.2083144 | 1 | 0 | 0 | 1.7047392 | 2.6742360 | ADORA3;DOC2B;ADRA2A;STXBP5L |
| 247 | regulation of hormone secretion (GO:0046883) | 7/230 | 0.2090308 | 1 | 0 | 0 | 1.4527343 | 2.2739268 | C1QTNF1;BMP8A;DOC2B;CACNA1E;ADRA2A;STXBP5L;NKX3-1 |
| 248 | regulation of chondrocyte differentiation (GO:0032330) | 2/41 | 0.2119125 | 1 | 0 | 0 | 2.3284242 | 3.6127403 | ZBTB16;PTHLH |
| 249 | positive regulation of wound healing (GO:0090303) | 2/41 | 0.2119125 | 1 | 0 | 0 | 2.3284242 | 3.6127403 | THBS1;ADRA2A |
| 250 | epidermal cell differentiation (GO:0009913) | 3/76 | 0.2132832 | 1 | 0 | 0 | 1.8841854 | 2.9113198 | CDSN;PAX6;WNT16 |
| 251 | regulation of protein kinase B signaling (GO:0051896) | 4/114 | 0.2170882 | 1 | 0 | 0 | 1.6748315 | 2.5582241 | NTRK2;CSF3;C1QTNF1;THBS1 |
| 252 | G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger (GO:0007187) | 5/153 | 0.2182608 | 1 | 0 | 0 | 1.5598921 | 2.3742563 | GPR37;ADM2;GRM8;ADRA2A;PTHLH |
| 253 | regulation of lyase activity (GO:0051339) | 3/77 | 0.2187594 | 1 | 0 | 0 | 1.8597155 | 2.8263638 | NTRK2;ADORA3;ADRA2A |
| 254 | fatty acid derivative biosynthetic process (GO:1901570) | 2/42 | 0.2196341 | 1 | 0 | 0 | 2.2729856 | 3.4453738 | EDN2;PTGS2 |
| 255 | negative regulation of epithelial cell migration (GO:0010633) | 2/42 | 0.2196341 | 1 | 0 | 0 | 2.2729856 | 3.4453738 | STC1;THBS1 |
| 256 | icosanoid biosynthetic process (GO:0046456) | 2/42 | 0.2196341 | 1 | 0 | 0 | 2.2729856 | 3.4453738 | EDN2;PTGS2 |
| 257 | sterol transport (GO:0015918) | 2/42 | 0.2196341 | 1 | 0 | 0 | 2.2729856 | 3.4453738 | LIPG;APOB |
| 258 | cholesterol transport (GO:0030301) | 2/42 | 0.2196341 | 1 | 0 | 0 | 2.2729856 | 3.4453738 | LIPG;APOB |
| 259 | positive regulation of protein kinase B signaling (GO:0051897) | 3/78 | 0.2242642 | 1 | 0 | 0 | 1.8358730 | 2.7445025 | CSF3;C1QTNF1;THBS1 |
| 260 | axis specification (GO:0009798) | 3/78 | 0.2242642 | 1 | 0 | 0 | 1.8358730 | 2.7445025 | SIX3;STC1;PAX6 |
| 261 | extracellular fibril organization (GO:0043206) | 1/12 | 0.2244175 | 1 | 0 | 0 | 3.9777247 | 5.9437046 | MUC5AC |
| 262 | regulation of tolerance induction (GO:0002643) | 1/12 | 0.2244175 | 1 | 0 | 0 | 3.9777247 | 5.9437046 | IRAK3 |
| 263 | positive regulation of myeloid leukocyte mediated immunity (GO:0002888) | 1/12 | 0.2244175 | 1 | 0 | 0 | 3.9777247 | 5.9437046 | ADORA3 |
| 264 | positive regulation of hormone metabolic process (GO:0032352) | 1/12 | 0.2244175 | 1 | 0 | 0 | 3.9777247 | 5.9437046 | CYP17A1 |
| 265 | response to manganese ion (GO:0010042) | 1/12 | 0.2244175 | 1 | 0 | 0 | 3.9777247 | 5.9437046 | PTGS2 |
| 266 | lens fiber cell differentiation (GO:0070306) | 1/12 | 0.2244175 | 1 | 0 | 0 | 3.9777247 | 5.9437046 | SIX3 |
| 267 | positive regulation of cellular amine metabolic process (GO:0033240) | 1/12 | 0.2244175 | 1 | 0 | 0 | 3.9777247 | 5.9437046 | GPR37 |
| 268 | negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator (GO:1902166) | 1/12 | 0.2244175 | 1 | 0 | 0 | 3.9777247 | 5.9437046 | MUC1 |
| 269 | regulation of corticosteroid hormone secretion (GO:2000846) | 1/12 | 0.2244175 | 1 | 0 | 0 | 3.9777247 | 5.9437046 | C1QTNF1 |
| 270 | G-protein coupled acetylcholine receptor signaling pathway (GO:0007213) | 1/12 | 0.2244175 | 1 | 0 | 0 | 3.9777247 | 5.9437046 | CHRM1 |
| 271 | positive regulation of actin cytoskeleton reorganization (GO:2000251) | 1/12 | 0.2244175 | 1 | 0 | 0 | 3.9777247 | 5.9437046 | CSF3 |
| 272 | amino acid import (GO:0043090) | 1/12 | 0.2244175 | 1 | 0 | 0 | 3.9777247 | 5.9437046 | SLC6A1 |
| 273 | astrocyte differentiation (GO:0048708) | 1/12 | 0.2244175 | 1 | 0 | 0 | 3.9777247 | 5.9437046 | PAX6 |
| 274 | regulation of development, heterochronic (GO:0040034) | 1/12 | 0.2244175 | 1 | 0 | 0 | 3.9777247 | 5.9437046 | PAX6 |
| 275 | nonmotile primary cilium assembly (GO:0035058) | 1/12 | 0.2244175 | 1 | 0 | 0 | 3.9777247 | 5.9437046 | PCDH15 |
| 276 | regulation of platelet aggregation (GO:0090330) | 1/12 | 0.2244175 | 1 | 0 | 0 | 3.9777247 | 5.9437046 | C1QTNF1 |
| 277 | startle response (GO:0001964) | 1/12 | 0.2244175 | 1 | 0 | 0 | 3.9777247 | 5.9437046 | PCDH15 |
| 278 | regulation of macrophage cytokine production (GO:0010935) | 1/12 | 0.2244175 | 1 | 0 | 0 | 3.9777247 | 5.9437046 | IRAK3 |
| 279 | negative regulation of catecholamine secretion (GO:0033604) | 1/12 | 0.2244175 | 1 | 0 | 0 | 3.9777247 | 5.9437046 | ADRA2A |
| 280 | chemical homeostasis within a tissue (GO:0048875) | 1/12 | 0.2244175 | 1 | 0 | 0 | 3.9777247 | 5.9437046 | PTHLH |
| 281 | interleukin-1-mediated signaling pathway (GO:0070498) | 1/12 | 0.2244175 | 1 | 0 | 0 | 3.9777247 | 5.9437046 | IRAK3 |
| 282 | endothelial cell morphogenesis (GO:0001886) | 1/12 | 0.2244175 | 1 | 0 | 0 | 3.9777247 | 5.9437046 | STC1 |
| 283 | regulation of cholesterol biosynthetic process (GO:0045540) | 1/12 | 0.2244175 | 1 | 0 | 0 | 3.9777247 | 5.9437046 | APOB |
| 284 | iron coordination entity transport (GO:1901678) | 1/12 | 0.2244175 | 1 | 0 | 0 | 3.9777247 | 5.9437046 | LCN2 |
| 285 | positive regulation of leukocyte degranulation (GO:0043302) | 1/12 | 0.2244175 | 1 | 0 | 0 | 3.9777247 | 5.9437046 | ADORA3 |
| 286 | positive regulation of mast cell activation (GO:0033005) | 1/12 | 0.2244175 | 1 | 0 | 0 | 3.9777247 | 5.9437046 | ADORA3 |
| 287 | determination of adult lifespan (GO:0008340) | 1/12 | 0.2244175 | 1 | 0 | 0 | 3.9777247 | 5.9437046 | TFCP2L1 |
| 288 | regulation of receptor binding (GO:1900120) | 1/12 | 0.2244175 | 1 | 0 | 0 | 3.9777247 | 5.9437046 | NKX3-1 |
| 289 | linoleic acid metabolic process (GO:0043651) | 1/12 | 0.2244175 | 1 | 0 | 0 | 3.9777247 | 5.9437046 | ALOX15B |
| 290 | mesonephros development (GO:0001823) | 1/12 | 0.2244175 | 1 | 0 | 0 | 3.9777247 | 5.9437046 | ZBTB16 |
| 291 | negative regulation of blood coagulation (GO:0030195) | 2/43 | 0.2273788 | 1 | 0 | 0 | 2.2201254 | 3.2883123 | C1QTNF1;PLAT |
| 292 | regulation of organic acid transport (GO:0032890) | 2/43 | 0.2273788 | 1 | 0 | 0 | 2.2201254 | 3.2883123 | SLC6A1;THBS1 |
| 293 | negative regulation of hemostasis (GO:1900047) | 2/43 | 0.2273788 | 1 | 0 | 0 | 2.2201254 | 3.2883123 | C1QTNF1;PLAT |
| 294 | regulation of blood coagulation (GO:0030193) | 3/79 | 0.2297959 | 1 | 0 | 0 | 1.8126341 | 2.6655940 | C1QTNF1;PLAT;THBS1 |
| 295 | calcium-mediated signaling (GO:0019722) | 3/79 | 0.2297959 | 1 | 0 | 0 | 1.8126341 | 2.6655940 | NTRK2;EDN2;BHLHA15 |
| 296 | regulation of hemostasis (GO:1900046) | 3/79 | 0.2297959 | 1 | 0 | 0 | 1.8126341 | 2.6655940 | C1QTNF1;PLAT;THBS1 |
| 297 | response to organophosphorus (GO:0046683) | 4/118 | 0.2349238 | 1 | 0 | 0 | 1.6180575 | 2.3437466 | STC1;PLAT;PTGS2;CYP17A1 |
| 298 | hormone biosynthetic process (GO:0042446) | 2/44 | 0.2351421 | 1 | 0 | 0 | 2.1696680 | 3.1407358 | TPO;CYP17A1 |
| 299 | connective tissue development (GO:0061448) | 2/44 | 0.2351421 | 1 | 0 | 0 | 2.1696680 | 3.1407358 | COMP;THBS1 |
| 300 | Leydig cell differentiation (GO:0033327) | 1/13 | 0.2406756 | 1 | 0 | 0 | 3.6717459 | 5.2296866 | CYP17A1 |
| 301 | drug catabolic process (GO:0042737) | 1/13 | 0.2406756 | 1 | 0 | 0 | 3.6717459 | 5.2296866 | CYP3A5 |
| 302 | thyroid hormone generation (GO:0006590) | 1/13 | 0.2406756 | 1 | 0 | 0 | 3.6717459 | 5.2296866 | TPO |
| 303 | chronic inflammatory response (GO:0002544) | 1/13 | 0.2406756 | 1 | 0 | 0 | 3.6717459 | 5.2296866 | THBS1 |
| 304 | establishment of tissue polarity (GO:0007164) | 1/13 | 0.2406756 | 1 | 0 | 0 | 3.6717459 | 5.2296866 | CTHRC1 |
| 305 | positive regulation of systemic arterial blood pressure (GO:0003084) | 1/13 | 0.2406756 | 1 | 0 | 0 | 3.6717459 | 5.2296866 | HSD11B2 |
| 306 | sulfation (GO:0051923) | 1/13 | 0.2406756 | 1 | 0 | 0 | 3.6717459 | 5.2296866 | SULT1C2 |
| 307 | phagocytosis, engulfment (GO:0006911) | 1/13 | 0.2406756 | 1 | 0 | 0 | 3.6717459 | 5.2296866 | THBS1 |
| 308 | response to auditory stimulus (GO:0010996) | 1/13 | 0.2406756 | 1 | 0 | 0 | 3.6717459 | 5.2296866 | NTRK2 |
| 309 | establishment of planar polarity (GO:0001736) | 1/13 | 0.2406756 | 1 | 0 | 0 | 3.6717459 | 5.2296866 | CTHRC1 |
| 310 | positive regulation of fatty acid biosynthetic process (GO:0045723) | 1/13 | 0.2406756 | 1 | 0 | 0 | 3.6717459 | 5.2296866 | PTGS2 |
| 311 | calcium-mediated signaling using intracellular calcium source (GO:0035584) | 1/13 | 0.2406756 | 1 | 0 | 0 | 3.6717459 | 5.2296866 | NTRK2 |
| 312 | lipoprotein transport (GO:0042953) | 1/13 | 0.2406756 | 1 | 0 | 0 | 3.6717459 | 5.2296866 | APOB |
| 313 | cellular response to antibiotic (GO:0071236) | 1/13 | 0.2406756 | 1 | 0 | 0 | 3.6717459 | 5.2296866 | CYP17A1 |
| 314 | lung secretory cell differentiation (GO:0061140) | 1/13 | 0.2406756 | 1 | 0 | 0 | 3.6717459 | 5.2296866 | SPDEF |
| 315 | keratinocyte proliferation (GO:0043616) | 1/13 | 0.2406756 | 1 | 0 | 0 | 3.6717459 | 5.2296866 | WNT16 |
| 316 | regulation of cholesterol storage (GO:0010885) | 1/13 | 0.2406756 | 1 | 0 | 0 | 3.6717459 | 5.2296866 | APOB |
| 317 | sulfate transmembrane transport (GO:1902358) | 1/13 | 0.2406756 | 1 | 0 | 0 | 3.6717459 | 5.2296866 | SLC26A2 |
| 318 | regulation of lipoprotein particle clearance (GO:0010984) | 1/13 | 0.2406756 | 1 | 0 | 0 | 3.6717459 | 5.2296866 | LIPG |
| 319 | negative regulation of cell fate commitment (GO:0010454) | 1/13 | 0.2406756 | 1 | 0 | 0 | 3.6717459 | 5.2296866 | SPDEF |
| 320 | vascular smooth muscle contraction (GO:0014829) | 1/13 | 0.2406756 | 1 | 0 | 0 | 3.6717459 | 5.2296866 | EDN2 |
| 321 | sodium-independent organic anion transport (GO:0043252) | 1/13 | 0.2406756 | 1 | 0 | 0 | 3.6717459 | 5.2296866 | SLCO1B3 |
| 322 | branching involved in prostate gland morphogenesis (GO:0060442) | 1/13 | 0.2406756 | 1 | 0 | 0 | 3.6717459 | 5.2296866 | NKX3-1 |
| 323 | phenol-containing compound metabolic process (GO:0018958) | 3/81 | 0.2409331 | 1 | 0 | 0 | 1.7678777 | 2.5161070 | TPO;GPR37;CYP17A1 |
| 324 | response to hypoxia (GO:0001666) | 7/241 | 0.2426279 | 1 | 0 | 0 | 1.3864269 | 1.9634941 | HSD11B2;MUC1;STC1;PLAT;PTGS2;THBS1;NKX3-1 |
| 325 | regulation of interleukin-12 production (GO:0032655) | 2/45 | 0.2429200 | 1 | 0 | 0 | 2.1214532 | 3.0019049 | IRAK3;THBS1 |
| 326 | negative regulation of ion transmembrane transport (GO:0034766) | 2/45 | 0.2429200 | 1 | 0 | 0 | 2.1214532 | 3.0019049 | THBS1;ADRA2A |
| 327 | regulation of cellular response to oxidative stress (GO:1900407) | 2/45 | 0.2429200 | 1 | 0 | 0 | 2.1214532 | 3.0019049 | GPR37;PYCR1 |
| 328 | regulation of blood vessel endothelial cell migration (GO:0043535) | 2/45 | 0.2429200 | 1 | 0 | 0 | 2.1214532 | 3.0019049 | PTGS2;THBS1 |
| 329 | positive regulation of cyclic nucleotide biosynthetic process (GO:0030804) | 3/82 | 0.2465352 | 1 | 0 | 0 | 1.7463182 | 2.4452827 | NTRK2;ADORA3;PTHLH |
| 330 | positive regulation of ossification (GO:0045778) | 3/83 | 0.2521575 | 1 | 0 | 0 | 1.7252782 | 2.3769184 | FBN2;ZBTB16;CTHRC1 |
| 331 | response to decreased oxygen levels (GO:0036293) | 7/245 | 0.2552533 | 1 | 0 | 0 | 1.3637913 | 1.8622555 | HSD11B2;MUC1;STC1;PLAT;PTGS2;THBS1;NKX3-1 |
| 332 | progesterone metabolic process (GO:0042448) | 1/14 | 0.2565938 | 1 | 0 | 0 | 3.4094783 | 4.6377803 | CYP17A1 |
| 333 | adrenergic receptor signaling pathway (GO:0071875) | 1/14 | 0.2565938 | 1 | 0 | 0 | 3.4094783 | 4.6377803 | ADRA2A |
| 334 | cell proliferation in forebrain (GO:0021846) | 1/14 | 0.2565938 | 1 | 0 | 0 | 3.4094783 | 4.6377803 | SIX3 |
| 335 | regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator (GO:1902165) | 1/14 | 0.2565938 | 1 | 0 | 0 | 3.4094783 | 4.6377803 | MUC1 |
| 336 | inositol phosphate-mediated signaling (GO:0048016) | 1/14 | 0.2565938 | 1 | 0 | 0 | 3.4094783 | 4.6377803 | EDN2 |
| 337 | response to magnesium ion (GO:0032026) | 1/14 | 0.2565938 | 1 | 0 | 0 | 3.4094783 | 4.6377803 | THBS1 |
| 338 | G-protein coupled glutamate receptor signaling pathway (GO:0007216) | 1/14 | 0.2565938 | 1 | 0 | 0 | 3.4094783 | 4.6377803 | GRM8 |
| 339 | high-density lipoprotein particle remodeling (GO:0034375) | 1/14 | 0.2565938 | 1 | 0 | 0 | 3.4094783 | 4.6377803 | LIPG |
| 340 | gland morphogenesis (GO:0022612) | 1/14 | 0.2565938 | 1 | 0 | 0 | 3.4094783 | 4.6377803 | PAX6 |
| 341 | negative regulation of fibroblast growth factor receptor signaling pathway (GO:0040037) | 1/14 | 0.2565938 | 1 | 0 | 0 | 3.4094783 | 4.6377803 | THBS1 |
| 342 | purine ribonucleoside diphosphate metabolic process (GO:0009179) | 1/14 | 0.2565938 | 1 | 0 | 0 | 3.4094783 | 4.6377803 | ENTPD2 |
| 343 | purine nucleoside diphosphate metabolic process (GO:0009135) | 1/14 | 0.2565938 | 1 | 0 | 0 | 3.4094783 | 4.6377803 | ENTPD2 |
| 344 | macrophage chemotaxis (GO:0048246) | 1/14 | 0.2565938 | 1 | 0 | 0 | 3.4094783 | 4.6377803 | EDN2 |
| 345 | dorsal/ventral axis specification (GO:0009950) | 1/14 | 0.2565938 | 1 | 0 | 0 | 3.4094783 | 4.6377803 | PAX6 |
| 346 | regulation of steroid hormone biosynthetic process (GO:0090030) | 1/14 | 0.2565938 | 1 | 0 | 0 | 3.4094783 | 4.6377803 | CYP17A1 |
| 347 | DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator (GO:0006978) | 1/14 | 0.2565938 | 1 | 0 | 0 | 3.4094783 | 4.6377803 | MUC1 |
| 348 | fibril organization (GO:0097435) | 1/14 | 0.2565938 | 1 | 0 | 0 | 3.4094783 | 4.6377803 | MUC5AC |
| 349 | regulation of fibrinolysis (GO:0051917) | 1/14 | 0.2565938 | 1 | 0 | 0 | 3.4094783 | 4.6377803 | THBS1 |
| 350 | positive regulation of steroid biosynthetic process (GO:0010893) | 1/14 | 0.2565938 | 1 | 0 | 0 | 3.4094783 | 4.6377803 | CYP17A1 |
| 351 | regulation of actin filament-based movement (GO:1903115) | 1/14 | 0.2565938 | 1 | 0 | 0 | 3.4094783 | 4.6377803 | STC1 |
| 352 | reactive oxygen species metabolic process (GO:0072593) | 3/84 | 0.2577982 | 1 | 0 | 0 | 1.7047392 | 2.3109072 | TPO;PXDN;IL19 |
| 353 | positive regulation of purine nucleotide biosynthetic process (GO:1900373) | 3/84 | 0.2577982 | 1 | 0 | 0 | 1.7047392 | 2.3109072 | NTRK2;ADORA3;PTHLH |
| 354 | positive regulation of nucleotide biosynthetic process (GO:0030810) | 3/84 | 0.2577982 | 1 | 0 | 0 | 1.7047392 | 2.3109072 | NTRK2;ADORA3;PTHLH |
| 355 | adenylate cyclase-activating G-protein coupled receptor signaling pathway (GO:0007189) | 2/47 | 0.2585036 | 1 | 0 | 0 | 2.0311786 | 2.7478708 | ADM2;PTHLH |
| 356 | negative regulation of coagulation (GO:0050819) | 2/47 | 0.2585036 | 1 | 0 | 0 | 2.0311786 | 2.7478708 | C1QTNF1;PLAT |
| 357 | negative regulation of synaptic transmission (GO:0050805) | 2/47 | 0.2585036 | 1 | 0 | 0 | 2.0311786 | 2.7478708 | SLC6A1;PTGS2 |
| 358 | positive regulation of cyclase activity (GO:0031281) | 2/47 | 0.2585036 | 1 | 0 | 0 | 2.0311786 | 2.7478708 | NTRK2;ADORA3 |
| 359 | regulation of coagulation (GO:0050818) | 3/85 | 0.2634558 | 1 | 0 | 0 | 1.6846834 | 2.2471480 | C1QTNF1;PLAT;THBS1 |
| 360 | regulation of anion transport (GO:0044070) | 3/85 | 0.2634558 | 1 | 0 | 0 | 1.6846834 | 2.2471480 | STC1;SLC6A1;THBS1 |
| 361 | regulation of calcium ion transmembrane transport (GO:1903169) | 2/48 | 0.2663018 | 1 | 0 | 0 | 1.9888624 | 2.6315136 | JPH2;ADRA2A |
| 362 | regulation of calcium ion transmembrane transporter activity (GO:1901019) | 2/48 | 0.2663018 | 1 | 0 | 0 | 1.9888624 | 2.6315136 | JPH2;ADRA2A |
| 363 | positive regulation of intrinsic apoptotic signaling pathway (GO:2001244) | 2/48 | 0.2663018 | 1 | 0 | 0 | 1.9888624 | 2.6315136 | IL19;NKX3-1 |
| 364 | Rho protein signal transduction (GO:0007266) | 2/48 | 0.2663018 | 1 | 0 | 0 | 1.9888624 | 2.6315136 | CDC42EP5;ADRA2A |
| 365 | positive regulation of calcium ion-dependent exocytosis (GO:0045956) | 1/15 | 0.2721791 | 1 | 0 | 0 | 3.1821798 | 4.1409551 | DOC2B |
| 366 | androgen biosynthetic process (GO:0006702) | 1/15 | 0.2721791 | 1 | 0 | 0 | 3.1821798 | 4.1409551 | CYP17A1 |
| 367 | embryonic camera-type eye morphogenesis (GO:0048596) | 1/15 | 0.2721791 | 1 | 0 | 0 | 3.1821798 | 4.1409551 | PAX6 |
| 368 | glandular epithelial cell development (GO:0002068) | 1/15 | 0.2721791 | 1 | 0 | 0 | 3.1821798 | 4.1409551 | PAX6 |
| 369 | granulocyte differentiation (GO:0030851) | 1/15 | 0.2721791 | 1 | 0 | 0 | 3.1821798 | 4.1409551 | CSF3 |
| 370 | sulfate transport (GO:0008272) | 1/15 | 0.2721791 | 1 | 0 | 0 | 3.1821798 | 4.1409551 | SLC26A2 |
| 371 | regulation of norepinephrine secretion (GO:0014061) | 1/15 | 0.2721791 | 1 | 0 | 0 | 3.1821798 | 4.1409551 | ADRA2A |
| 372 | positive regulation of cholesterol transport (GO:0032376) | 1/15 | 0.2721791 | 1 | 0 | 0 | 3.1821798 | 4.1409551 | LIPG |
| 373 | regulation of cell migration involved in sprouting angiogenesis (GO:0090049) | 1/15 | 0.2721791 | 1 | 0 | 0 | 3.1821798 | 4.1409551 | PTGS2 |
| 374 | regulation of dopamine metabolic process (GO:0042053) | 1/15 | 0.2721791 | 1 | 0 | 0 | 3.1821798 | 4.1409551 | GPR37 |
| 375 | positive regulation of epidermal cell differentiation (GO:0045606) | 1/15 | 0.2721791 | 1 | 0 | 0 | 3.1821798 | 4.1409551 | ALOX15B |
| 376 | cyclooxygenase pathway (GO:0019371) | 1/15 | 0.2721791 | 1 | 0 | 0 | 3.1821798 | 4.1409551 | PTGS2 |
| 377 | acrosome reaction (GO:0007340) | 1/15 | 0.2721791 | 1 | 0 | 0 | 3.1821798 | 4.1409551 | SYT8 |
| 378 | pharyngeal system development (GO:0060037) | 1/15 | 0.2721791 | 1 | 0 | 0 | 3.1821798 | 4.1409551 | NKX3-1 |
| 379 | DNA damage response, signal transduction resulting in transcription (GO:0042772) | 1/15 | 0.2721791 | 1 | 0 | 0 | 3.1821798 | 4.1409551 | MUC1 |
| 380 | positive regulation of membrane protein ectodomain proteolysis (GO:0051044) | 1/15 | 0.2721791 | 1 | 0 | 0 | 3.1821798 | 4.1409551 | ADRA2A |
| 381 | response to food (GO:0032094) | 1/15 | 0.2721791 | 1 | 0 | 0 | 3.1821798 | 4.1409551 | HSD11B2 |
| 382 | negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator (GO:1902254) | 1/15 | 0.2721791 | 1 | 0 | 0 | 3.1821798 | 4.1409551 | MUC1 |
| 383 | detection of mechanical stimulus involved in sensory perception of sound (GO:0050910) | 1/15 | 0.2721791 | 1 | 0 | 0 | 3.1821798 | 4.1409551 | PCDH15 |
| 384 | hair cycle (GO:0042633) | 1/15 | 0.2721791 | 1 | 0 | 0 | 3.1821798 | 4.1409551 | PTGS2 |
| 385 | positive regulation of sterol transport (GO:0032373) | 1/15 | 0.2721791 | 1 | 0 | 0 | 3.1821798 | 4.1409551 | LIPG |
| 386 | extracellular negative regulation of signal transduction (GO:1900116) | 1/15 | 0.2721791 | 1 | 0 | 0 | 3.1821798 | 4.1409551 | FBN2 |
| 387 | extracellular regulation of signal transduction (GO:1900115) | 1/15 | 0.2721791 | 1 | 0 | 0 | 3.1821798 | 4.1409551 | FBN2 |
| 388 | negative regulation of chondrocyte differentiation (GO:0032331) | 1/15 | 0.2721791 | 1 | 0 | 0 | 3.1821798 | 4.1409551 | PTHLH |
| 389 | molting cycle (GO:0042303) | 1/15 | 0.2721791 | 1 | 0 | 0 | 3.1821798 | 4.1409551 | PTGS2 |
| 390 | renal system process involved in regulation of blood volume (GO:0001977) | 1/15 | 0.2721791 | 1 | 0 | 0 | 3.1821798 | 4.1409551 | HSD11B2 |
| 391 | dicarboxylic acid catabolic process (GO:0043649) | 1/15 | 0.2721791 | 1 | 0 | 0 | 3.1821798 | 4.1409551 | ALDH1L2 |
| 392 | negative regulation of platelet activation (GO:0010544) | 1/15 | 0.2721791 | 1 | 0 | 0 | 3.1821798 | 4.1409551 | C1QTNF1 |
| 393 | regulation of catecholamine metabolic process (GO:0042069) | 1/15 | 0.2721791 | 1 | 0 | 0 | 3.1821798 | 4.1409551 | GPR37 |
| 394 | regulation of response to oxidative stress (GO:1902882) | 2/49 | 0.2740994 | 1 | 0 | 0 | 1.9482733 | 2.5215808 | GPR37;PYCR1 |
| 395 | cellular glucose homeostasis (GO:0001678) | 2/49 | 0.2740994 | 1 | 0 | 0 | 1.9482733 | 2.5215808 | HKDC1;FOXA3 |
| 396 | positive regulation of exocytosis (GO:0045921) | 2/49 | 0.2740994 | 1 | 0 | 0 | 1.9482733 | 2.5215808 | ADORA3;DOC2B |
| 397 | fatty acid derivative metabolic process (GO:1901568) | 3/88 | 0.2805142 | 1 | 0 | 0 | 1.6272510 | 2.0684488 | EDN2;PTGS2;ALOX15B |
| 398 | positive regulation of inflammatory response (GO:0050729) | 3/88 | 0.2805142 | 1 | 0 | 0 | 1.6272510 | 2.0684488 | CCL24;ADORA3;PTGS2 |
| 399 | icosanoid metabolic process (GO:0006690) | 3/88 | 0.2805142 | 1 | 0 | 0 | 1.6272510 | 2.0684488 | EDN2;PTGS2;ALOX15B |
| 400 | regulation of insulin secretion (GO:0050796) | 5/169 | 0.2809033 | 1 | 0 | 0 | 1.4122100 | 1.7931463 | BMP8A;DOC2B;CACNA1E;ADRA2A;STXBP5L |
| 401 | determination of left/right symmetry (GO:0007368) | 2/50 | 0.2818931 | 1 | 0 | 0 | 1.9093079 | 2.4176177 | LEFTY1;DAAM2 |
| 402 | negative regulation of wound healing (GO:0061045) | 2/50 | 0.2818931 | 1 | 0 | 0 | 1.9093079 | 2.4176177 | C1QTNF1;PLAT |
| 403 | response to fatty acid (GO:0070542) | 2/50 | 0.2818931 | 1 | 0 | 0 | 1.9093079 | 2.4176177 | PTGS2;APOB |
| 404 | positive regulation of lyase activity (GO:0051349) | 2/50 | 0.2818931 | 1 | 0 | 0 | 1.9093079 | 2.4176177 | NTRK2;ADORA3 |
| 405 | tissue homeostasis (GO:0001894) | 4/129 | 0.2855315 | 1 | 0 | 0 | 1.4800836 | 1.8551413 | AZGP1;TFF1;PTHLH;MUC6 |
| 406 | cellular response to tumor necrosis factor (GO:0071356) | 3/89 | 0.2862238 | 1 | 0 | 0 | 1.6089673 | 2.0127878 | APOB;THBS1;NKX3-1 |
| 407 | fucosylation (GO:0036065) | 1/16 | 0.2874383 | 1 | 0 | 0 | 2.9832936 | 3.7194122 | FUT6 |
| 408 | cardiac myofibril assembly (GO:0055003) | 1/16 | 0.2874383 | 1 | 0 | 0 | 2.9832936 | 3.7194122 | MYLK3 |
| 409 | negative regulation of bone mineralization (GO:0030502) | 1/16 | 0.2874383 | 1 | 0 | 0 | 2.9832936 | 3.7194122 | AHSG |
| 410 | regulation of tumor necrosis factor biosynthetic process (GO:0042534) | 1/16 | 0.2874383 | 1 | 0 | 0 | 2.9832936 | 3.7194122 | THBS1 |
| 411 | positive regulation of extrinsic apoptotic signaling pathway via death domain receptors (GO:1902043) | 1/16 | 0.2874383 | 1 | 0 | 0 | 2.9832936 | 3.7194122 | THBS1 |
| 412 | thyroid hormone metabolic process (GO:0042403) | 1/16 | 0.2874383 | 1 | 0 | 0 | 2.9832936 | 3.7194122 | TPO |
| 413 | positive regulation of calcium ion import (GO:0090280) | 1/16 | 0.2874383 | 1 | 0 | 0 | 2.9832936 | 3.7194122 | STC1 |
| 414 | regulation of cellular senescence (GO:2000772) | 1/16 | 0.2874383 | 1 | 0 | 0 | 2.9832936 | 3.7194122 | NEK6 |
| 415 | fucose metabolic process (GO:0006004) | 1/16 | 0.2874383 | 1 | 0 | 0 | 2.9832936 | 3.7194122 | FUT6 |
| 416 | plasma lipoprotein particle assembly (GO:0034377) | 1/16 | 0.2874383 | 1 | 0 | 0 | 2.9832936 | 3.7194122 | APOB |
| 417 | reverse cholesterol transport (GO:0043691) | 1/16 | 0.2874383 | 1 | 0 | 0 | 2.9832936 | 3.7194122 | LIPG |
| 418 | behavioral response to pain (GO:0048266) | 1/16 | 0.2874383 | 1 | 0 | 0 | 2.9832936 | 3.7194122 | THBS1 |
| 419 | phasic smooth muscle contraction (GO:0014821) | 1/16 | 0.2874383 | 1 | 0 | 0 | 2.9832936 | 3.7194122 | EDN2 |
| 420 | columnar/cuboidal epithelial cell differentiation (GO:0002065) | 2/51 | 0.2896796 | 1 | 0 | 0 | 1.8718705 | 2.3192094 | PAX6;SPDEF |
| 421 | regulation of potassium ion transport (GO:0043266) | 2/51 | 0.2896796 | 1 | 0 | 0 | 1.8718705 | 2.3192094 | KCNN2;ADRA2A |
| 422 | negative regulation of transmembrane transport (GO:0034763) | 2/51 | 0.2896796 | 1 | 0 | 0 | 1.8718705 | 2.3192094 | THBS1;ADRA2A |
| 423 | circulatory system process (GO:0003013) | 4/130 | 0.2902174 | 1 | 0 | 0 | 1.4686984 | 1.8169632 | EDN2;TNNI3;MYLK3;F5 |
| 424 | response to glucocorticoid (GO:0051384) | 4/130 | 0.2902174 | 1 | 0 | 0 | 1.4686984 | 1.8169632 | HSD11B2;STC1;PLAT;PTGS2 |
| 425 | response to cAMP (GO:0051591) | 3/90 | 0.2919426 | 1 | 0 | 0 | 1.5910899 | 1.9589468 | STC1;PLAT;CYP17A1 |
| 426 | memory (GO:0007613) | 3/90 | 0.2919426 | 1 | 0 | 0 | 1.5910899 | 1.9589468 | NTRK2;CUX2;PTGS2 |
| 427 | positive regulation of epithelial cell differentiation (GO:0030858) | 2/52 | 0.2974559 | 1 | 0 | 0 | 1.8358730 | 2.2259765 | PAX6;ALOX15B |
| 428 | phospholipase C-activating G-protein coupled receptor signaling pathway (GO:0007200) | 2/52 | 0.2974559 | 1 | 0 | 0 | 1.8358730 | 2.2259765 | CHRM1;ADRA2A |
| 429 | positive regulation of lipid biosynthetic process (GO:0046889) | 2/52 | 0.2974559 | 1 | 0 | 0 | 1.8358730 | 2.2259765 | PTGS2;CYP17A1 |
| 430 | positive regulation of hormone secretion (GO:0046887) | 3/91 | 0.2976692 | 1 | 0 | 0 | 1.5736054 | 1.9068519 | C1QTNF1;DOC2B;NKX3-1 |
| 431 | positive regulation of cyclic nucleotide metabolic process (GO:0030801) | 3/91 | 0.2976692 | 1 | 0 | 0 | 1.5736054 | 1.9068519 | NTRK2;ADORA3;PTHLH |
| 432 | response to oxygen levels (GO:0070482) | 7/259 | 0.3008117 | 1 | 0 | 0 | 1.2900729 | 1.5497270 | HSD11B2;MUC1;STC1;PLAT;PTGS2;THBS1;NKX3-1 |
| 433 | cellular modified amino acid catabolic process (GO:0042219) | 1/17 | 0.3023784 | 1 | 0 | 0 | 2.8078057 | 3.3583490 | ALDH1L2 |
| 434 | positive regulation of regulated secretory pathway (GO:1903307) | 1/17 | 0.3023784 | 1 | 0 | 0 | 2.8078057 | 3.3583490 | ADORA3 |
| 435 | G-protein coupled purinergic receptor signaling pathway (GO:0035588) | 1/17 | 0.3023784 | 1 | 0 | 0 | 2.8078057 | 3.3583490 | ADORA3 |
| 436 | azole transport (GO:0045117) | 1/17 | 0.3023784 | 1 | 0 | 0 | 2.8078057 | 3.3583490 | ADORA3 |
| 437 | ribonucleoside bisphosphate biosynthetic process (GO:0034030) | 1/17 | 0.3023784 | 1 | 0 | 0 | 2.8078057 | 3.3583490 | SLC26A2 |
| 438 | negative regulation of organic acid transport (GO:0032891) | 1/17 | 0.3023784 | 1 | 0 | 0 | 2.8078057 | 3.3583490 | THBS1 |
| 439 | cofactor catabolic process (GO:0051187) | 1/17 | 0.3023784 | 1 | 0 | 0 | 2.8078057 | 3.3583490 | ALDH1L2 |
| 440 | purine nucleoside bisphosphate biosynthetic process (GO:0034033) | 1/17 | 0.3023784 | 1 | 0 | 0 | 2.8078057 | 3.3583490 | SLC26A2 |
| 441 | bone remodeling (GO:0046849) | 1/17 | 0.3023784 | 1 | 0 | 0 | 2.8078057 | 3.3583490 | WNT16 |
| 442 | nucleoside bisphosphate biosynthetic process (GO:0033866) | 1/17 | 0.3023784 | 1 | 0 | 0 | 2.8078057 | 3.3583490 | SLC26A2 |
| 443 | regulation of cell fate specification (GO:0042659) | 1/17 | 0.3023784 | 1 | 0 | 0 | 2.8078057 | 3.3583490 | PAX6 |
| 444 | regulation of vesicle fusion (GO:0031338) | 1/17 | 0.3023784 | 1 | 0 | 0 | 2.8078057 | 3.3583490 | DOC2B |
| 445 | ribonucleoside diphosphate metabolic process (GO:0009185) | 1/17 | 0.3023784 | 1 | 0 | 0 | 2.8078057 | 3.3583490 | ENTPD2 |
| 446 | muscle cell migration (GO:0014812) | 1/17 | 0.3023784 | 1 | 0 | 0 | 2.8078057 | 3.3583490 | PLAT |
| 447 | sex differentiation (GO:0007548) | 1/17 | 0.3023784 | 1 | 0 | 0 | 2.8078057 | 3.3583490 | CYP17A1 |
| 448 | regulation of endothelial cell migration (GO:0010594) | 3/92 | 0.3034021 | 1 | 0 | 0 | 1.5565010 | 1.8564331 | STC1;PTGS2;THBS1 |
| 449 | regulation of blood pressure (GO:0008217) | 4/133 | 0.3043351 | 1 | 0 | 0 | 1.4355698 | 1.7077909 | HSD11B2;EDN2;ADM2;PTGS2 |
| 450 | determination of bilateral symmetry (GO:0009855) | 2/53 | 0.3052188 | 1 | 0 | 0 | 1.8012338 | 2.1375715 | LEFTY1;DAAM2 |
| 451 | regulation of steroid biosynthetic process (GO:0050810) | 2/53 | 0.3052188 | 1 | 0 | 0 | 1.8012338 | 2.1375715 | APOB;CYP17A1 |
| 452 | positive regulation of protein binding (GO:0032092) | 2/53 | 0.3052188 | 1 | 0 | 0 | 1.8012338 | 2.1375715 | CSF3;CTHRC1 |
| 453 | granulocyte chemotaxis (GO:0071621) | 2/53 | 0.3052188 | 1 | 0 | 0 | 1.8012338 | 2.1375715 | CCL24;EDN2 |
| 454 | regulation of cartilage development (GO:0061035) | 2/54 | 0.3129657 | 1 | 0 | 0 | 1.7678777 | 2.0536758 | ZBTB16;PTHLH |
| 455 | specification of symmetry (GO:0009799) | 2/54 | 0.3129657 | 1 | 0 | 0 | 1.7678777 | 2.0536758 | LEFTY1;DAAM2 |
| 456 | gland development (GO:0048732) | 6/220 | 0.3146673 | 1 | 0 | 0 | 1.3018008 | 1.5051934 | SIX3;PAX6;TFCP2L1;ALOX15B;CYP17A1;NKX3-1 |
| 457 | cellular response to toxic substance (GO:0097237) | 1/18 | 0.3170060 | 1 | 0 | 0 | 2.6518165 | 3.0464985 | CYP17A1 |
| 458 | tetrahydrofolate metabolic process (GO:0046653) | 1/18 | 0.3170060 | 1 | 0 | 0 | 2.6518165 | 3.0464985 | ALDH1L2 |
| 459 | negative regulation of calcium ion transmembrane transport (GO:1903170) | 1/18 | 0.3170060 | 1 | 0 | 0 | 2.6518165 | 3.0464985 | ADRA2A |
| 460 | cytokine biosynthetic process (GO:0042089) | 1/18 | 0.3170060 | 1 | 0 | 0 | 2.6518165 | 3.0464985 | IL19 |
| 461 | catechol-containing compound biosynthetic process (GO:0009713) | 1/18 | 0.3170060 | 1 | 0 | 0 | 2.6518165 | 3.0464985 | GPR37 |
| 462 | negative regulation of cytokine production involved in immune response (GO:0002719) | 1/18 | 0.3170060 | 1 | 0 | 0 | 2.6518165 | 3.0464985 | IRAK3 |
| 463 | catecholamine biosynthetic process (GO:0042423) | 1/18 | 0.3170060 | 1 | 0 | 0 | 2.6518165 | 3.0464985 | GPR37 |
| 464 | fibrinolysis (GO:0042730) | 1/18 | 0.3170060 | 1 | 0 | 0 | 2.6518165 | 3.0464985 | PLAT |
| 465 | olfactory bulb development (GO:0021772) | 1/18 | 0.3170060 | 1 | 0 | 0 | 2.6518165 | 3.0464985 | FEZF1 |
| 466 | telencephalon development (GO:0021537) | 1/18 | 0.3170060 | 1 | 0 | 0 | 2.6518165 | 3.0464985 | SIX3 |
| 467 | regulation of intrinsic apoptotic signaling pathway by p53 class mediator (GO:1902253) | 1/18 | 0.3170060 | 1 | 0 | 0 | 2.6518165 | 3.0464985 | MUC1 |
| 468 | positive regulation of excitatory postsynaptic membrane potential (GO:2000463) | 1/18 | 0.3170060 | 1 | 0 | 0 | 2.6518165 | 3.0464985 | CUX2 |
| 469 | cellular response to gonadotropin stimulus (GO:0071371) | 1/18 | 0.3170060 | 1 | 0 | 0 | 2.6518165 | 3.0464985 | CYP17A1 |
| 470 | negative regulation of calcium ion transmembrane transporter activity (GO:1901020) | 1/18 | 0.3170060 | 1 | 0 | 0 | 2.6518165 | 3.0464985 | ADRA2A |
| 471 | phospholipid translocation (GO:0045332) | 1/18 | 0.3170060 | 1 | 0 | 0 | 2.6518165 | 3.0464985 | ATP10B |
| 472 | virion assembly (GO:0019068) | 1/18 | 0.3170060 | 1 | 0 | 0 | 2.6518165 | 3.0464985 | RAB43 |
| 473 | regulation of antigen processing and presentation (GO:0002577) | 1/18 | 0.3170060 | 1 | 0 | 0 | 2.6518165 | 3.0464985 | THBS1 |
| 474 | hindbrain development (GO:0030902) | 1/18 | 0.3170060 | 1 | 0 | 0 | 2.6518165 | 3.0464985 | PAX6 |
| 475 | glutamate secretion (GO:0014047) | 1/18 | 0.3170060 | 1 | 0 | 0 | 2.6518165 | 3.0464985 | NTRK2 |
| 476 | protein-lipid complex assembly (GO:0065005) | 1/18 | 0.3170060 | 1 | 0 | 0 | 2.6518165 | 3.0464985 | APOB |
| 477 | positive regulation of dendritic spine development (GO:0060999) | 1/18 | 0.3170060 | 1 | 0 | 0 | 2.6518165 | 3.0464985 | CUX2 |
| 478 | lipid translocation (GO:0034204) | 1/18 | 0.3170060 | 1 | 0 | 0 | 2.6518165 | 3.0464985 | ATP10B |
| 479 | regulation of mast cell degranulation (GO:0043304) | 1/18 | 0.3170060 | 1 | 0 | 0 | 2.6518165 | 3.0464985 | ADORA3 |
| 480 | positive regulation of chondrocyte differentiation (GO:0032332) | 1/18 | 0.3170060 | 1 | 0 | 0 | 2.6518165 | 3.0464985 | ZBTB16 |
| 481 | negative regulation of biomineral tissue development (GO:0070168) | 1/18 | 0.3170060 | 1 | 0 | 0 | 2.6518165 | 3.0464985 | AHSG |
| 482 | positive regulation of lipid storage (GO:0010884) | 1/18 | 0.3170060 | 1 | 0 | 0 | 2.6518165 | 3.0464985 | APOB |
| 483 | regulation of synaptic transmission, dopaminergic (GO:0032225) | 1/18 | 0.3170060 | 1 | 0 | 0 | 2.6518165 | 3.0464985 | PTGS2 |
| 484 | regulation of Rac GTPase activity (GO:0032314) | 1/18 | 0.3170060 | 1 | 0 | 0 | 2.6518165 | 3.0464985 | NTRK2 |
| 485 | protein glycosylation (GO:0006486) | 7/264 | 0.3174937 | 1 | 0 | 0 | 1.2656397 | 1.4520649 | FUT6;MUC1;B3GNT6;MUC3A;ABO;MUC5AC;MUC6 |
| 486 | macromolecule glycosylation (GO:0043413) | 7/264 | 0.3174937 | 1 | 0 | 0 | 1.2656397 | 1.4520649 | FUT6;MUC1;B3GNT6;MUC3A;ABO;MUC5AC;MUC6 |
| 487 | positive regulation of endothelial cell migration (GO:0010595) | 2/55 | 0.3206937 | 1 | 0 | 0 | 1.7357344 | 1.9739967 | PTGS2;THBS1 |
| 488 | arachidonic acid metabolic process (GO:0019369) | 2/55 | 0.3206937 | 1 | 0 | 0 | 1.7357344 | 1.9739967 | PTGS2;ALOX15B |
| 489 | granulocyte migration (GO:0097530) | 2/55 | 0.3206937 | 1 | 0 | 0 | 1.7357344 | 1.9739967 | CCL24;EDN2 |
| 490 | positive regulation of leukocyte chemotaxis (GO:0002690) | 2/56 | 0.3284002 | 1 | 0 | 0 | 1.7047392 | 1.8982650 | EDN2;THBS1 |
| 491 | positive regulation of neuroblast proliferation (GO:0002052) | 1/19 | 0.3313276 | 1 | 0 | 0 | 2.5122472 | 2.7751481 | PAX6 |
| 492 | reflex (GO:0060004) | 1/19 | 0.3313276 | 1 | 0 | 0 | 2.5122472 | 2.7751481 | PCDH15 |
| 493 | regulation of fibroblast migration (GO:0010762) | 1/19 | 0.3313276 | 1 | 0 | 0 | 2.5122472 | 2.7751481 | THBS1 |
| 494 | cardiac epithelial to mesenchymal transition (GO:0060317) | 1/19 | 0.3313276 | 1 | 0 | 0 | 2.5122472 | 2.7751481 | WNT16 |
| 495 | osteoblast development (GO:0002076) | 1/19 | 0.3313276 | 1 | 0 | 0 | 2.5122472 | 2.7751481 | PTHLH |
| 496 | appendage development (GO:0048736) | 1/19 | 0.3313276 | 1 | 0 | 0 | 2.5122472 | 2.7751481 | COMP |
| 497 | positive regulation of calcium ion transmembrane transporter activity (GO:1901021) | 1/19 | 0.3313276 | 1 | 0 | 0 | 2.5122472 | 2.7751481 | JPH2 |
| 498 | triglyceride catabolic process (GO:0019433) | 1/19 | 0.3313276 | 1 | 0 | 0 | 2.5122472 | 2.7751481 | APOB |
| 499 | limb development (GO:0060173) | 1/19 | 0.3313276 | 1 | 0 | 0 | 2.5122472 | 2.7751481 | COMP |
| 500 | regulation of membrane protein ectodomain proteolysis (GO:0051043) | 1/19 | 0.3313276 | 1 | 0 | 0 | 2.5122472 | 2.7751481 | ADRA2A |
| 501 | positive regulation of heart rate (GO:0010460) | 1/19 | 0.3313276 | 1 | 0 | 0 | 2.5122472 | 2.7751481 | EDN2 |
| 502 | intestinal absorption (GO:0050892) | 1/19 | 0.3313276 | 1 | 0 | 0 | 2.5122472 | 2.7751481 | ADRA2A |
| 503 | glutamine family amino acid biosynthetic process (GO:0009084) | 1/19 | 0.3313276 | 1 | 0 | 0 | 2.5122472 | 2.7751481 | PYCR1 |
| 504 | positive regulation of histone acetylation (GO:0035066) | 1/19 | 0.3313276 | 1 | 0 | 0 | 2.5122472 | 2.7751481 | MUC1 |
| 505 | regulation of mast cell activation involved in immune response (GO:0033006) | 1/19 | 0.3313276 | 1 | 0 | 0 | 2.5122472 | 2.7751481 | ADORA3 |
| 506 | membrane invagination (GO:0010324) | 1/19 | 0.3313276 | 1 | 0 | 0 | 2.5122472 | 2.7751481 | THBS1 |
| 507 | response to carbohydrate (GO:0009743) | 4/139 | 0.3327663 | 1 | 0 | 0 | 1.3736028 | 1.5113956 | APOB;SLC6A1;PTGS2;THBS1 |
| 508 | Golgi organization (GO:0007030) | 2/57 | 0.3360828 | 1 | 0 | 0 | 1.6748315 | 1.8262323 | RAB43;BHLHA15 |
| 509 | neurotransmitter secretion (GO:0007269) | 2/57 | 0.3360828 | 1 | 0 | 0 | 1.6748315 | 1.8262323 | DOC2B;SLC6A1 |
| 510 | dicarboxylic acid transport (GO:0006835) | 2/57 | 0.3360828 | 1 | 0 | 0 | 1.6748315 | 1.8262323 | NTRK2;SLC13A5 |
| 511 | response to corticosteroid (GO:0031960) | 4/140 | 0.3375210 | 1 | 0 | 0 | 1.3637913 | 1.4812513 | HSD11B2;STC1;PLAT;PTGS2 |
| 512 | cell cycle arrest (GO:0007050) | 4/140 | 0.3375210 | 1 | 0 | 0 | 1.3637913 | 1.4812513 | CGREF1;BRINP1;THBS1;NKX3-1 |
| 513 | cellular response to hypoxia (GO:0071456) | 3/99 | 0.3435957 | 1 | 0 | 0 | 1.4464454 | 1.5452227 | STC1;PTGS2;NKX3-1 |
| 514 | negative regulation of lipid catabolic process (GO:0050995) | 1/20 | 0.3453496 | 1 | 0 | 0 | 2.3866348 | 2.5374656 | ADRA2A |
| 515 | regulation of osteoblast proliferation (GO:0033688) | 1/20 | 0.3453496 | 1 | 0 | 0 | 2.3866348 | 2.5374656 | CTHRC1 |
| 516 | regulation of transcription involved in cell fate commitment (GO:0060850) | 1/20 | 0.3453496 | 1 | 0 | 0 | 2.3866348 | 2.5374656 | PAX6 |
| 517 | renal system process involved in regulation of systemic arterial blood pressure (GO:0003071) | 1/20 | 0.3453496 | 1 | 0 | 0 | 2.3866348 | 2.5374656 | HSD11B2 |
| 518 | positive regulation of organelle assembly (GO:1902117) | 1/20 | 0.3453496 | 1 | 0 | 0 | 2.3866348 | 2.5374656 | MYLK3 |
| 519 | neuromuscular synaptic transmission (GO:0007274) | 1/20 | 0.3453496 | 1 | 0 | 0 | 2.3866348 | 2.5374656 | CHRM1 |
| 520 | positive regulation of epidermal growth factor receptor signaling pathway (GO:0045742) | 1/20 | 0.3453496 | 1 | 0 | 0 | 2.3866348 | 2.5374656 | ADRA2A |
| 521 | negative regulation of cartilage development (GO:0061037) | 1/20 | 0.3453496 | 1 | 0 | 0 | 2.3866348 | 2.5374656 | PTHLH |
| 522 | acidic amino acid transport (GO:0015800) | 1/20 | 0.3453496 | 1 | 0 | 0 | 2.3866348 | 2.5374656 | SLC6A1 |
| 523 | regulation of amino acid transport (GO:0051955) | 1/20 | 0.3453496 | 1 | 0 | 0 | 2.3866348 | 2.5374656 | SLC6A1 |
| 524 | cobalamin metabolic process (GO:0009235) | 1/20 | 0.3453496 | 1 | 0 | 0 | 2.3866348 | 2.5374656 | TCN1 |
| 525 | regulation of cholesterol metabolic process (GO:0090181) | 1/20 | 0.3453496 | 1 | 0 | 0 | 2.3866348 | 2.5374656 | APOB |
| 526 | negative regulation of striated muscle cell differentiation (GO:0051154) | 1/20 | 0.3453496 | 1 | 0 | 0 | 2.3866348 | 2.5374656 | CEACAM5 |
| 527 | response to prostaglandin (GO:0034694) | 1/20 | 0.3453496 | 1 | 0 | 0 | 2.3866348 | 2.5374656 | APOB |
| 528 | plasma lipoprotein particle clearance (GO:0034381) | 1/20 | 0.3453496 | 1 | 0 | 0 | 2.3866348 | 2.5374656 | APOB |
| 529 | activation of protein kinase B activity (GO:0032148) | 1/20 | 0.3453496 | 1 | 0 | 0 | 2.3866348 | 2.5374656 | ADRA2A |
| 530 | regulation of homotypic cell-cell adhesion (GO:0034110) | 1/20 | 0.3453496 | 1 | 0 | 0 | 2.3866348 | 2.5374656 | C1QTNF1 |
| 531 | negative regulation of blood vessel endothelial cell migration (GO:0043537) | 1/20 | 0.3453496 | 1 | 0 | 0 | 2.3866348 | 2.5374656 | THBS1 |
| 532 | positive regulation of cytoskeleton organization (GO:0051495) | 4/142 | 0.3470374 | 1 | 0 | 0 | 1.3445830 | 1.4230026 | CCL24;CSF3;CDC42EP5;MYLK3 |
| 533 | glycosylation (GO:0070085) | 7/273 | 0.3478975 | 1 | 0 | 0 | 1.2239153 | 1.2922679 | FUT6;MUC1;B3GNT6;MUC3A;ABO;MUC5AC;MUC6 |
| 534 | positive regulation of secretion (GO:0051047) | 7/273 | 0.3478975 | 1 | 0 | 0 | 1.2239153 | 1.2922679 | C1QTNF1;ADORA3;DOC2B;SLC6A1;ALOX15B;STXBP5L;NKX3-1 |
| 535 | response to estradiol (GO:0032355) | 3/100 | 0.3493311 | 1 | 0 | 0 | 1.4319809 | 1.5060645 | TFF1;SLC6A1;PTGS2 |
| 536 | unsaturated fatty acid metabolic process (GO:0033559) | 3/100 | 0.3493311 | 1 | 0 | 0 | 1.4319809 | 1.5060645 | EDN2;PTGS2;ALOX15B |
| 537 | positive regulation of ion transport (GO:0043270) | 5/186 | 0.3506516 | 1 | 0 | 0 | 1.2831370 | 1.3446791 | JPH2;CHRM1;STC1;SLC6A1;ADRA2A |
| 538 | positive regulation of osteoblast differentiation (GO:0045669) | 2/59 | 0.3513668 | 1 | 0 | 0 | 1.6180575 | 1.6923662 | FBN2;CTHRC1 |
| 539 | acute inflammatory response (GO:0002526) | 2/59 | 0.3513668 | 1 | 0 | 0 | 1.6180575 | 1.6923662 | AHSG;ADRA2A |
| 540 | cellular response to decreased oxygen levels (GO:0036294) | 3/101 | 0.3550613 | 1 | 0 | 0 | 1.4178029 | 1.4680850 | STC1;PTGS2;NKX3-1 |
| 541 | regulation of peptide transport (GO:0090087) | 6/231 | 0.3553968 | 1 | 0 | 0 | 1.2398103 | 1.2826091 | BMP8A;DOC2B;PTGS2;CACNA1E;ADRA2A;STXBP5L |
| 542 | regulation of amine transport (GO:0051952) | 2/60 | 0.3589637 | 1 | 0 | 0 | 1.5910899 | 1.6301255 | SLC6A1;ADRA2A |
| 543 | negative regulation of production of molecular mediator of immune response (GO:0002701) | 1/21 | 0.3590782 | 1 | 0 | 0 | 2.2729856 | 2.3280260 | IRAK3 |
| 544 | positive regulation of T cell mediated cytotoxicity (GO:0001916) | 1/21 | 0.3590782 | 1 | 0 | 0 | 2.2729856 | 2.3280260 | AZGP1 |
| 545 | neutral lipid catabolic process (GO:0046461) | 1/21 | 0.3590782 | 1 | 0 | 0 | 2.2729856 | 2.3280260 | APOB |
| 546 | positive regulation of peptidyl-lysine acetylation (GO:2000758) | 1/21 | 0.3590782 | 1 | 0 | 0 | 2.2729856 | 2.3280260 | MUC1 |
| 547 | acylglycerol catabolic process (GO:0046464) | 1/21 | 0.3590782 | 1 | 0 | 0 | 2.2729856 | 2.3280260 | APOB |
| 548 | regulation of insulin-like growth factor receptor signaling pathway (GO:0043567) | 1/21 | 0.3590782 | 1 | 0 | 0 | 2.2729856 | 2.3280260 | NKX3-1 |
| 549 | negative regulation of exocytosis (GO:0045920) | 1/21 | 0.3590782 | 1 | 0 | 0 | 2.2729856 | 2.3280260 | ADRA2A |
| 550 | embryonic eye morphogenesis (GO:0048048) | 1/21 | 0.3590782 | 1 | 0 | 0 | 2.2729856 | 2.3280260 | PAX6 |
| 551 | C21-steroid hormone metabolic process (GO:0008207) | 1/21 | 0.3590782 | 1 | 0 | 0 | 2.2729856 | 2.3280260 | CYP17A1 |
| 552 | regulation of dendritic spine morphogenesis (GO:0061001) | 1/21 | 0.3590782 | 1 | 0 | 0 | 2.2729856 | 2.3280260 | CUX2 |
| 553 | mechanoreceptor differentiation (GO:0042490) | 1/21 | 0.3590782 | 1 | 0 | 0 | 2.2729856 | 2.3280260 | NTRK2 |
| 554 | positive regulation of dendrite morphogenesis (GO:0050775) | 1/21 | 0.3590782 | 1 | 0 | 0 | 2.2729856 | 2.3280260 | CUX2 |
| 555 | positive regulation of ERBB signaling pathway (GO:1901186) | 1/21 | 0.3590782 | 1 | 0 | 0 | 2.2729856 | 2.3280260 | ADRA2A |
| 556 | positive regulation of protein acetylation (GO:1901985) | 1/21 | 0.3590782 | 1 | 0 | 0 | 2.2729856 | 2.3280260 | MUC1 |
| 557 | regulation of peptide hormone secretion (GO:0090276) | 5/189 | 0.3631093 | 1 | 0 | 0 | 1.2627698 | 1.2792506 | BMP8A;DOC2B;CACNA1E;ADRA2A;STXBP5L |
| 558 | glial cell differentiation (GO:0010001) | 2/61 | 0.3665279 | 1 | 0 | 0 | 1.5650065 | 1.5707667 | NTRK2;PAX6 |
| 559 | sensory perception of smell (GO:0007608) | 2/61 | 0.3665279 | 1 | 0 | 0 | 1.5650065 | 1.5707667 | OMP;GRM8 |
| 560 | cholesterol homeostasis (GO:0042632) | 2/61 | 0.3665279 | 1 | 0 | 0 | 1.5650065 | 1.5707667 | LIPG;APOB |
| 561 | response to steroid hormone (GO:0048545) | 9/369 | 0.3691084 | 1 | 0 | 0 | 1.1642121 | 1.1603295 | HSD11B2;STC1;TFF1;PLAT;SLC6A1;PTGS2;THBS1;CYP17A1;NKX3-1 |
| 562 | regulation of actin filament polymerization (GO:0030833) | 3/104 | 0.3722086 | 1 | 0 | 0 | 1.3769047 | 1.3607960 | CCL24;CSF3;CDC42EP5 |
| 563 | Wnt signaling pathway, planar cell polarity pathway (GO:0060071) | 1/22 | 0.3725196 | 1 | 0 | 0 | 2.1696680 | 2.1424725 | CTHRC1 |
| 564 | cochlea morphogenesis (GO:0090103) | 1/22 | 0.3725196 | 1 | 0 | 0 | 2.1696680 | 2.1424725 | CTHRC1 |
| 565 | regulation of hormone biosynthetic process (GO:0046885) | 1/22 | 0.3725196 | 1 | 0 | 0 | 2.1696680 | 2.1424725 | CYP17A1 |
| 566 | myofibril assembly (GO:0030239) | 1/22 | 0.3725196 | 1 | 0 | 0 | 2.1696680 | 2.1424725 | MYLK3 |
| 567 | negative regulation of toll-like receptor signaling pathway (GO:0034122) | 1/22 | 0.3725196 | 1 | 0 | 0 | 2.1696680 | 2.1424725 | IRAK3 |
| 568 | negative regulation of amine transport (GO:0051953) | 1/22 | 0.3725196 | 1 | 0 | 0 | 2.1696680 | 2.1424725 | ADRA2A |
| 569 | cytokine metabolic process (GO:0042107) | 1/22 | 0.3725196 | 1 | 0 | 0 | 2.1696680 | 2.1424725 | IL19 |
| 570 | mitochondrion localization (GO:0051646) | 1/22 | 0.3725196 | 1 | 0 | 0 | 2.1696680 | 2.1424725 | BHLHA15 |
| 571 | signal transduction involved in regulation of gene expression (GO:0023019) | 1/22 | 0.3725196 | 1 | 0 | 0 | 2.1696680 | 2.1424725 | PAX6 |
| 572 | apoptotic process involved in development (GO:1902742) | 1/22 | 0.3725196 | 1 | 0 | 0 | 2.1696680 | 2.1424725 | SIX3 |
| 573 | cellular response to hydrogen peroxide (GO:0070301) | 2/62 | 0.3740573 | 1 | 0 | 0 | 1.5397644 | 1.5141217 | TPO;PXDN |
| 574 | sterol homeostasis (GO:0055092) | 2/62 | 0.3740573 | 1 | 0 | 0 | 1.5397644 | 1.5141217 | LIPG;APOB |
| 575 | cellular response to retinoic acid (GO:0071300) | 2/62 | 0.3740573 | 1 | 0 | 0 | 1.5397644 | 1.5141217 | MUC1;BRINP1 |
| 576 | regulation of peptide secretion (GO:0002791) | 5/192 | 0.3755773 | 1 | 0 | 0 | 1.2430390 | 1.2172969 | BMP8A;DOC2B;CACNA1E;ADRA2A;STXBP5L |
| 577 | cellular response to oxidative stress (GO:0034599) | 4/148 | 0.3755906 | 1 | 0 | 0 | 1.2900729 | 1.2633110 | TPO;PXDN;PYCR1;WNT16 |
| 578 | response to transition metal nanoparticle (GO:1990267) | 3/106 | 0.3835932 | 1 | 0 | 0 | 1.3509254 | 1.2944199 | TFF1;PTGS2;CYP17A1 |
| 579 | response to ATP (GO:0033198) | 1/23 | 0.3856798 | 1 | 0 | 0 | 2.0753346 | 1.9772706 | PTGS2 |
| 580 | oligodendrocyte differentiation (GO:0048709) | 1/23 | 0.3856798 | 1 | 0 | 0 | 2.0753346 | 1.9772706 | NTRK2 |
| 581 | cell aggregation (GO:0098743) | 1/23 | 0.3856798 | 1 | 0 | 0 | 2.0753346 | 1.9772706 | CHAD |
| 582 | regulation of establishment of planar polarity (GO:0090175) | 1/23 | 0.3856798 | 1 | 0 | 0 | 2.0753346 | 1.9772706 | CTHRC1 |
| 583 | regulation of keratinocyte differentiation (GO:0045616) | 1/23 | 0.3856798 | 1 | 0 | 0 | 2.0753346 | 1.9772706 | ALOX15B |
| 584 | benzene-containing compound metabolic process (GO:0042537) | 1/23 | 0.3856798 | 1 | 0 | 0 | 2.0753346 | 1.9772706 | CYP17A1 |
| 585 | positive regulation vascular endothelial growth factor production (GO:0010575) | 1/23 | 0.3856798 | 1 | 0 | 0 | 2.0753346 | 1.9772706 | PTGS2 |
| 586 | positive regulation of potassium ion transport (GO:0043268) | 1/23 | 0.3856798 | 1 | 0 | 0 | 2.0753346 | 1.9772706 | ADRA2A |
| 587 | positive regulation of transforming growth factor beta receptor signaling pathway (GO:0030511) | 1/23 | 0.3856798 | 1 | 0 | 0 | 2.0753346 | 1.9772706 | THBS1 |
| 588 | positive regulation of NF-kappaB import into nucleus (GO:0042346) | 1/23 | 0.3856798 | 1 | 0 | 0 | 2.0753346 | 1.9772706 | PTGS2 |
| 589 | cholesterol efflux (GO:0033344) | 1/23 | 0.3856798 | 1 | 0 | 0 | 2.0753346 | 1.9772706 | APOB |
| 590 | positive regulation of organic acid transport (GO:0032892) | 1/23 | 0.3856798 | 1 | 0 | 0 | 2.0753346 | 1.9772706 | SLC6A1 |
| 591 | positive regulation of amine transport (GO:0051954) | 1/23 | 0.3856798 | 1 | 0 | 0 | 2.0753346 | 1.9772706 | SLC6A1 |
| 592 | multicellular organism reproduction (GO:0032504) | 1/23 | 0.3856798 | 1 | 0 | 0 | 2.0753346 | 1.9772706 | CATSPERB |
| 593 | regulation of macrophage activation (GO:0043030) | 1/23 | 0.3856798 | 1 | 0 | 0 | 2.0753346 | 1.9772706 | THBS1 |
| 594 | regulation of fatty acid transport (GO:2000191) | 1/23 | 0.3856798 | 1 | 0 | 0 | 2.0753346 | 1.9772706 | THBS1 |
| 595 | positive regulation of steroid metabolic process (GO:0045940) | 1/23 | 0.3856798 | 1 | 0 | 0 | 2.0753346 | 1.9772706 | CYP17A1 |
| 596 | cartilage condensation (GO:0001502) | 1/23 | 0.3856798 | 1 | 0 | 0 | 2.0753346 | 1.9772706 | CHAD |
| 597 | steroid metabolic process (GO:0008202) | 6/240 | 0.3890023 | 1 | 0 | 0 | 1.1933174 | 1.1266944 | HSD11B2;SLCO1B3;TFCP2L1;APOB;CYP3A5;CYP17A1 |
| 598 | central nervous system development (GO:0007417) | 3/108 | 0.3949304 | 1 | 0 | 0 | 1.3259082 | 1.2318294 | SNTG2;ZBTB16;PAX6 |
| 599 | inorganic anion transmembrane transport (GO:0098661) | 3/108 | 0.3949304 | 1 | 0 | 0 | 1.3259082 | 1.2318294 | ANO1;SLC26A2;ANO7 |
| 600 | steroid biosynthetic process (GO:0006694) | 3/108 | 0.3949304 | 1 | 0 | 0 | 1.3259082 | 1.2318294 | HSD11B2;TFCP2L1;CYP17A1 |
| 601 | regulation of neural precursor cell proliferation (GO:2000177) | 2/65 | 0.3964187 | 1 | 0 | 0 | 1.4686984 | 1.3589636 | SIX3;PAX6 |
| 602 | trabecula formation (GO:0060343) | 1/24 | 0.3985646 | 1 | 0 | 0 | 1.9888624 | 1.8295261 | FBN2 |
| 603 | regulation of cell aging (GO:0090342) | 1/24 | 0.3985646 | 1 | 0 | 0 | 1.9888624 | 1.8295261 | NEK6 |
| 604 | regulation of epidermal growth factor-activated receptor activity (GO:0007176) | 1/24 | 0.3985646 | 1 | 0 | 0 | 1.9888624 | 1.8295261 | ADRA2A |
| 605 | phospholipid catabolic process (GO:0009395) | 1/24 | 0.3985646 | 1 | 0 | 0 | 1.9888624 | 1.8295261 | LIPG |
| 606 | embryonic hemopoiesis (GO:0035162) | 1/24 | 0.3985646 | 1 | 0 | 0 | 1.9888624 | 1.8295261 | TPO |
| 607 | regulation of actin cytoskeleton reorganization (GO:2000249) | 1/24 | 0.3985646 | 1 | 0 | 0 | 1.9888624 | 1.8295261 | CSF3 |
| 608 | adrenal gland development (GO:0030325) | 1/24 | 0.3985646 | 1 | 0 | 0 | 1.9888624 | 1.8295261 | CYP17A1 |
| 609 | negative regulation of adenylate cyclase activity (GO:0007194) | 1/24 | 0.3985646 | 1 | 0 | 0 | 1.9888624 | 1.8295261 | ADRA2A |
| 610 | positive regulation of blood coagulation (GO:0030194) | 1/24 | 0.3985646 | 1 | 0 | 0 | 1.9888624 | 1.8295261 | THBS1 |
| 611 | sprouting angiogenesis (GO:0002040) | 1/24 | 0.3985646 | 1 | 0 | 0 | 1.9888624 | 1.8295261 | THBS1 |
| 612 | bile acid and bile salt transport (GO:0015721) | 1/24 | 0.3985646 | 1 | 0 | 0 | 1.9888624 | 1.8295261 | SLCO1B3 |
| 613 | endoderm development (GO:0007492) | 1/24 | 0.3985646 | 1 | 0 | 0 | 1.9888624 | 1.8295261 | PTHLH |
| 614 | cardiac ventricle morphogenesis (GO:0003208) | 1/24 | 0.3985646 | 1 | 0 | 0 | 1.9888624 | 1.8295261 | CPE |
| 615 | carbohydrate phosphorylation (GO:0046835) | 1/24 | 0.3985646 | 1 | 0 | 0 | 1.9888624 | 1.8295261 | HKDC1 |
| 616 | protein import into nucleus, translocation (GO:0000060) | 1/24 | 0.3985646 | 1 | 0 | 0 | 1.9888624 | 1.8295261 | SIX3 |
| 617 | positive regulation of hemostasis (GO:1900048) | 1/24 | 0.3985646 | 1 | 0 | 0 | 1.9888624 | 1.8295261 | THBS1 |
| 618 | response to molecule of bacterial origin (GO:0002237) | 6/243 | 0.4002119 | 1 | 0 | 0 | 1.1785851 | 1.0793025 | CSF3;IRAK3;APOB;PTGS2;CXCL2;CYP17A1 |
| 619 | cellular response to oxygen levels (GO:0071453) | 3/109 | 0.4005788 | 1 | 0 | 0 | 1.3137440 | 1.2018719 | STC1;PTGS2;NKX3-1 |
| 620 | regulation of bone mineralization (GO:0030500) | 2/66 | 0.4037913 | 1 | 0 | 0 | 1.4464454 | 1.3117193 | FBN2;AHSG |
| 621 | dorsal/ventral pattern formation (GO:0009953) | 2/66 | 0.4037913 | 1 | 0 | 0 | 1.4464454 | 1.3117193 | SIX3;PAX6 |
| 622 | multicellular organismal response to stress (GO:0033555) | 2/66 | 0.4037913 | 1 | 0 | 0 | 1.4464454 | 1.3117193 | THBS1;ADRA2A |
| 623 | digestion (GO:0007586) | 2/66 | 0.4037913 | 1 | 0 | 0 | 1.4464454 | 1.3117193 | ADM2;TFF1 |
| 624 | negative regulation of epithelial cell proliferation (GO:0050680) | 3/110 | 0.4062124 | 1 | 0 | 0 | 1.3018008 | 1.1727652 | PAX6;THBS1;NKX3-1 |
| 625 | vasculogenesis (GO:0001570) | 2/67 | 0.4111207 | 1 | 0 | 0 | 1.4248566 | 1.2665099 | NTRK2;TNNI3 |
| 626 | regulation of myeloid leukocyte mediated immunity (GO:0002886) | 1/25 | 0.4111798 | 1 | 0 | 0 | 1.9093079 | 1.6968492 | ADORA3 |
| 627 | negative regulation of signal transduction by p53 class mediator (GO:1901797) | 1/25 | 0.4111798 | 1 | 0 | 0 | 1.9093079 | 1.6968492 | MUC1 |
| 628 | negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage (GO:1902230) | 1/25 | 0.4111798 | 1 | 0 | 0 | 1.9093079 | 1.6968492 | MUC1 |
| 629 | regulation of excretion (GO:0044062) | 1/25 | 0.4111798 | 1 | 0 | 0 | 1.9093079 | 1.6968492 | STC1 |
| 630 | regulation of T cell mediated cytotoxicity (GO:0001914) | 1/25 | 0.4111798 | 1 | 0 | 0 | 1.9093079 | 1.6968492 | AZGP1 |
| 631 | purinergic receptor signaling pathway (GO:0035587) | 1/25 | 0.4111798 | 1 | 0 | 0 | 1.9093079 | 1.6968492 | ADORA3 |
| 632 | folic acid-containing compound metabolic process (GO:0006760) | 1/25 | 0.4111798 | 1 | 0 | 0 | 1.9093079 | 1.6968492 | ALDH1L2 |
| 633 | negative regulation of cyclase activity (GO:0031280) | 1/25 | 0.4111798 | 1 | 0 | 0 | 1.9093079 | 1.6968492 | ADRA2A |
| 634 | response to iron ion (GO:0010039) | 1/25 | 0.4111798 | 1 | 0 | 0 | 1.9093079 | 1.6968492 | TFF1 |
| 635 | positive regulation of cartilage development (GO:0061036) | 1/25 | 0.4111798 | 1 | 0 | 0 | 1.9093079 | 1.6968492 | ZBTB16 |
| 636 | positive regulation of calcium-mediated signaling (GO:0050850) | 1/25 | 0.4111798 | 1 | 0 | 0 | 1.9093079 | 1.6968492 | ADORA3 |
| 637 | regulation of ryanodine-sensitive calcium-release channel activity (GO:0060314) | 1/25 | 0.4111798 | 1 | 0 | 0 | 1.9093079 | 1.6968492 | JPH2 |
| 638 | pancreas development (GO:0031016) | 1/25 | 0.4111798 | 1 | 0 | 0 | 1.9093079 | 1.6968492 | MSLN |
| 639 | negative regulation of cell-matrix adhesion (GO:0001953) | 1/25 | 0.4111798 | 1 | 0 | 0 | 1.9093079 | 1.6968492 | THBS1 |
| 640 | regulation of leukocyte degranulation (GO:0043300) | 1/25 | 0.4111798 | 1 | 0 | 0 | 1.9093079 | 1.6968492 | ADORA3 |
| 641 | positive regulation of synapse assembly (GO:0051965) | 1/25 | 0.4111798 | 1 | 0 | 0 | 1.9093079 | 1.6968492 | CUX2 |
| 642 | response to lithium ion (GO:0010226) | 1/25 | 0.4111798 | 1 | 0 | 0 | 1.9093079 | 1.6968492 | PTGS2 |
| 643 | detection of mechanical stimulus involved in sensory perception (GO:0050974) | 1/25 | 0.4111798 | 1 | 0 | 0 | 1.9093079 | 1.6968492 | PCDH15 |
| 644 | fatty acid biosynthetic process (GO:0006633) | 3/111 | 0.4118303 | 1 | 0 | 0 | 1.2900729 | 1.1444802 | EDN2;PTGS2;ALOX15B |
| 645 | response to retinoic acid (GO:0032526) | 3/111 | 0.4118303 | 1 | 0 | 0 | 1.2900729 | 1.1444802 | MUC1;BRINP1;CYP17A1 |
| 646 | positive regulation of response to external stimulus (GO:0032103) | 5/201 | 0.4129169 | 1 | 0 | 0 | 1.1873805 | 1.0502486 | CCL24;EDN2;ADORA3;PTGS2;THBS1 |
| 647 | xenobiotic metabolic process (GO:0006805) | 4/156 | 0.4134666 | 1 | 0 | 0 | 1.2239153 | 1.0809356 | SULT1C2;SLC26A2;CYP3A5;CYP17A1 |
| 648 | positive regulation of secretion by cell (GO:1903532) | 6/247 | 0.4151390 | 1 | 0 | 0 | 1.1594987 | 1.0193640 | C1QTNF1;ADORA3;DOC2B;ALOX15B;STXBP5L;NKX3-1 |
| 649 | regulation of leukocyte chemotaxis (GO:0002688) | 2/68 | 0.4184056 | 1 | 0 | 0 | 1.4039028 | 1.2232262 | EDN2;THBS1 |
| 650 | regulation of lipid biosynthetic process (GO:0046890) | 3/113 | 0.4230156 | 1 | 0 | 0 | 1.2672397 | 1.0902650 | APOB;PTGS2;CYP17A1 |
| 651 | positive regulation of acute inflammatory response (GO:0002675) | 1/26 | 0.4235310 | 1 | 0 | 0 | 1.8358730 | 1.5772510 | PTGS2 |
| 652 | positive regulation of coagulation (GO:0050820) | 1/26 | 0.4235310 | 1 | 0 | 0 | 1.8358730 | 1.5772510 | THBS1 |
| 653 | regulation of the force of heart contraction (GO:0002026) | 1/26 | 0.4235310 | 1 | 0 | 0 | 1.8358730 | 1.5772510 | EDN2 |
| 654 | positive regulation of heart contraction (GO:0045823) | 1/26 | 0.4235310 | 1 | 0 | 0 | 1.8358730 | 1.5772510 | EDN2 |
| 655 | negative regulation of insulin receptor signaling pathway (GO:0046627) | 1/26 | 0.4235310 | 1 | 0 | 0 | 1.8358730 | 1.5772510 | AHSG |
| 656 | stem cell division (GO:0017145) | 1/26 | 0.4235310 | 1 | 0 | 0 | 1.8358730 | 1.5772510 | ZBTB16 |
| 657 | macrophage activation (GO:0042116) | 1/26 | 0.4235310 | 1 | 0 | 0 | 1.8358730 | 1.5772510 | EDN2 |
| 658 | positive regulation of vasoconstriction (GO:0045907) | 1/26 | 0.4235310 | 1 | 0 | 0 | 1.8358730 | 1.5772510 | PTGS2 |
| 659 | positive regulation of vasodilation (GO:0045909) | 1/26 | 0.4235310 | 1 | 0 | 0 | 1.8358730 | 1.5772510 | ADRA2A |
| 660 | regulation of calcium ion import (GO:0090279) | 1/26 | 0.4235310 | 1 | 0 | 0 | 1.8358730 | 1.5772510 | STC1 |
| 661 | positive regulation of cation channel activity (GO:2001259) | 1/26 | 0.4235310 | 1 | 0 | 0 | 1.8358730 | 1.5772510 | JPH2 |
| 662 | positive regulation of membrane potential (GO:0045838) | 1/26 | 0.4235310 | 1 | 0 | 0 | 1.8358730 | 1.5772510 | CUX2 |
| 663 | prostate gland epithelium morphogenesis (GO:0060740) | 1/26 | 0.4235310 | 1 | 0 | 0 | 1.8358730 | 1.5772510 | NKX3-1 |
| 664 | negative regulation of lyase activity (GO:0051350) | 1/26 | 0.4235310 | 1 | 0 | 0 | 1.8358730 | 1.5772510 | ADRA2A |
| 665 | positive regulation of epidermis development (GO:0045684) | 1/26 | 0.4235310 | 1 | 0 | 0 | 1.8358730 | 1.5772510 | ALOX15B |
| 666 | regulation of blood circulation (GO:1903522) | 5/204 | 0.4253023 | 1 | 0 | 0 | 1.1699190 | 1.0002283 | EDN2;ADORA3;STC1;PTGS2;ADRA2A |
| 667 | positive regulation of muscle cell differentiation (GO:0051149) | 2/70 | 0.4328361 | 1 | 0 | 0 | 1.3637913 | 1.1420335 | CDH15;MYLK3 |
| 668 | negative regulation of cell adhesion (GO:0007162) | 3/115 | 0.4341277 | 1 | 0 | 0 | 1.2452008 | 1.0390162 | ADAMDEC1;C1QTNF1;THBS1 |
| 669 | learning (GO:0007612) | 3/115 | 0.4341277 | 1 | 0 | 0 | 1.2452008 | 1.0390162 | NTRK2;SLC6A1;PTGS2 |
| 670 | regulation of vascular permeability (GO:0043114) | 1/27 | 0.4356237 | 1 | 0 | 0 | 1.7678777 | 1.4690648 | MYLK3 |
| 671 | temperature homeostasis (GO:0001659) | 1/27 | 0.4356237 | 1 | 0 | 0 | 1.7678777 | 1.4690648 | EDN2 |
| 672 | cardiac chamber morphogenesis (GO:0003206) | 1/27 | 0.4356237 | 1 | 0 | 0 | 1.7678777 | 1.4690648 | CPE |
| 673 | negative regulation of lipid transport (GO:0032369) | 1/27 | 0.4356237 | 1 | 0 | 0 | 1.7678777 | 1.4690648 | THBS1 |
| 674 | regulation of vascular endothelial growth factor production (GO:0010574) | 1/27 | 0.4356237 | 1 | 0 | 0 | 1.7678777 | 1.4690648 | PTGS2 |
| 675 | negative regulation of endothelial cell proliferation (GO:0001937) | 1/27 | 0.4356237 | 1 | 0 | 0 | 1.7678777 | 1.4690648 | THBS1 |
| 676 | sarcomere organization (GO:0045214) | 1/27 | 0.4356237 | 1 | 0 | 0 | 1.7678777 | 1.4690648 | MYLK3 |
| 677 | cellular response to fatty acid (GO:0071398) | 1/27 | 0.4356237 | 1 | 0 | 0 | 1.7678777 | 1.4690648 | APOB |
| 678 | response to gonadotropin (GO:0034698) | 1/27 | 0.4356237 | 1 | 0 | 0 | 1.7678777 | 1.4690648 | CYP17A1 |
| 679 | developmental induction (GO:0031128) | 1/27 | 0.4356237 | 1 | 0 | 0 | 1.7678777 | 1.4690648 | SIX3 |
| 680 | regulation of mast cell activation (GO:0033003) | 1/27 | 0.4356237 | 1 | 0 | 0 | 1.7678777 | 1.4690648 | ADORA3 |
| 681 | regulation of platelet activation (GO:0010543) | 1/27 | 0.4356237 | 1 | 0 | 0 | 1.7678777 | 1.4690648 | C1QTNF1 |
| 682 | neuron migration (GO:0001764) | 3/116 | 0.4396542 | 1 | 0 | 0 | 1.2344663 | 1.0144433 | NTRK2;PAX6;FEZF1 |
| 683 | skeletal system development (GO:0001501) | 4/162 | 0.4415524 | 1 | 0 | 0 | 1.1785851 | 0.9634445 | COMP;AHSG;ZBTB16;PTHLH |
| 684 | regulation of response to wounding (GO:1903034) | 8/347 | 0.4421392 | 1 | 0 | 0 | 1.1004656 | 0.8981235 | CCL24;C1QTNF1;AHSG;ADORA3;PLAT;PTGS2;THBS1;ADRA2A |
| 685 | positive regulation of ion transmembrane transport (GO:0034767) | 2/72 | 0.4470730 | 1 | 0 | 0 | 1.3259082 | 1.0674003 | JPH2;STC1 |
| 686 | regulation of biomineral tissue development (GO:0070167) | 2/72 | 0.4470730 | 1 | 0 | 0 | 1.3259082 | 1.0674003 | FBN2;AHSG |
| 687 | fear response (GO:0042596) | 1/28 | 0.4474633 | 1 | 0 | 0 | 1.7047392 | 1.3708842 | ADRA2A |
| 688 | long-term memory (GO:0007616) | 1/28 | 0.4474633 | 1 | 0 | 0 | 1.7047392 | 1.3708842 | NTRK2 |
| 689 | glycerolipid catabolic process (GO:0046503) | 1/28 | 0.4474633 | 1 | 0 | 0 | 1.7047392 | 1.3708842 | APOB |
| 690 | dopamine metabolic process (GO:0042417) | 1/28 | 0.4474633 | 1 | 0 | 0 | 1.7047392 | 1.3708842 | GPR37 |
| 691 | positive regulation of fatty acid metabolic process (GO:0045923) | 1/28 | 0.4474633 | 1 | 0 | 0 | 1.7047392 | 1.3708842 | PTGS2 |
| 692 | cell-cell signaling involved in cell fate commitment (GO:0045168) | 1/28 | 0.4474633 | 1 | 0 | 0 | 1.7047392 | 1.3708842 | SIX3 |
| 693 | cellular senescence (GO:0090398) | 1/28 | 0.4474633 | 1 | 0 | 0 | 1.7047392 | 1.3708842 | WNT16 |
| 694 | negative regulation of innate immune response (GO:0045824) | 1/28 | 0.4474633 | 1 | 0 | 0 | 1.7047392 | 1.3708842 | IRAK3 |
| 695 | negative regulation of cellular response to insulin stimulus (GO:1900077) | 1/28 | 0.4474633 | 1 | 0 | 0 | 1.7047392 | 1.3708842 | AHSG |
| 696 | epithelial cell differentiation (GO:0030855) | 7/303 | 0.4503696 | 1 | 0 | 0 | 1.1027356 | 0.8796375 | MUC1;CDSN;SIX3;PAX6;WNT16;PTHLH;SPDEF |
| 697 | cell maturation (GO:0048469) | 3/118 | 0.4506445 | 1 | 0 | 0 | 1.2135431 | 0.9672867 | SIX3;BHLHA15;TFCP2L1 |
| 698 | post-translational protein modification (GO:0043687) | 5/211 | 0.4539912 | 1 | 0 | 0 | 1.1311066 | 0.8932095 | MUC1;B3GNT6;MUC3A;MUC5AC;MUC6 |
| 699 | regulation of transcription factor import into nucleus (GO:0042990) | 2/73 | 0.4541161 | 1 | 0 | 0 | 1.3077451 | 1.0323371 | CSF3;PTGS2 |
| 700 | epithelial cell proliferation (GO:0050673) | 2/73 | 0.4541161 | 1 | 0 | 0 | 1.3077451 | 1.0323371 | WNT16;NKX3-1 |
| 701 | cellular response to heat (GO:0034605) | 1/29 | 0.4590552 | 1 | 0 | 0 | 1.6459551 | 1.2815157 | THBS1 |
| 702 | regulation of fibroblast growth factor receptor signaling pathway (GO:0040036) | 1/29 | 0.4590552 | 1 | 0 | 0 | 1.6459551 | 1.2815157 | THBS1 |
| 703 | lung epithelial cell differentiation (GO:0060487) | 1/29 | 0.4590552 | 1 | 0 | 0 | 1.6459551 | 1.2815157 | SPDEF |
| 704 | vitamin transport (GO:0051180) | 1/29 | 0.4590552 | 1 | 0 | 0 | 1.6459551 | 1.2815157 | TCN1 |
| 705 | regulation of fatty acid biosynthetic process (GO:0042304) | 1/29 | 0.4590552 | 1 | 0 | 0 | 1.6459551 | 1.2815157 | PTGS2 |
| 706 | non-canonical Wnt signaling pathway (GO:0035567) | 1/29 | 0.4590552 | 1 | 0 | 0 | 1.6459551 | 1.2815157 | CTHRC1 |
| 707 | blood vessel morphogenesis (GO:0048514) | 2/74 | 0.4611076 | 1 | 0 | 0 | 1.2900729 | 0.9986763 | APOB;THBS1 |
| 708 | regulation of synaptic plasticity (GO:0048167) | 3/120 | 0.4615461 | 1 | 0 | 0 | 1.1933174 | 0.9226411 | NTRK2;PLAT;PTGS2 |
| 709 | response to vitamin (GO:0033273) | 2/75 | 0.4680465 | 1 | 0 | 0 | 1.2728719 | 0.9663487 | STC1;PTGS2 |
| 710 | platelet-derived growth factor receptor signaling pathway (GO:0048008) | 1/30 | 0.4704044 | 1 | 0 | 0 | 1.5910899 | 1.1999403 | PLAT |
| 711 | positive regulation of multicellular organismal metabolic process (GO:0044253) | 1/30 | 0.4704044 | 1 | 0 | 0 | 1.5910899 | 1.1999403 | BMP8A |
| 712 | regulation of hormone metabolic process (GO:0032350) | 1/30 | 0.4704044 | 1 | 0 | 0 | 1.5910899 | 1.1999403 | CYP17A1 |
| 713 | embryonic hindlimb morphogenesis (GO:0035116) | 1/30 | 0.4704044 | 1 | 0 | 0 | 1.5910899 | 1.1999403 | ZBTB16 |
| 714 | central nervous system neuron development (GO:0021954) | 1/30 | 0.4704044 | 1 | 0 | 0 | 1.5910899 | 1.1999403 | NTRK2 |
| 715 | long-term synaptic potentiation (GO:0060291) | 1/30 | 0.4704044 | 1 | 0 | 0 | 1.5910899 | 1.1999403 | NTRK2 |
| 716 | regulation of regulated secretory pathway (GO:1903305) | 1/30 | 0.4704044 | 1 | 0 | 0 | 1.5910899 | 1.1999403 | ADORA3 |
| 717 | positive regulation of receptor activity (GO:2000273) | 1/30 | 0.4704044 | 1 | 0 | 0 | 1.5910899 | 1.1999403 | ADRA2A |
| 718 | circadian behavior (GO:0048512) | 1/30 | 0.4704044 | 1 | 0 | 0 | 1.5910899 | 1.1999403 | SIX3 |
| 719 | regulation of granulocyte chemotaxis (GO:0071622) | 1/30 | 0.4704044 | 1 | 0 | 0 | 1.5910899 | 1.1999403 | THBS1 |
| 720 | endochondral ossification (GO:0001958) | 1/30 | 0.4704044 | 1 | 0 | 0 | 1.5910899 | 1.1999403 | PTHLH |
| 721 | lung cell differentiation (GO:0060479) | 1/30 | 0.4704044 | 1 | 0 | 0 | 1.5910899 | 1.1999403 | SPDEF |
| 722 | vasoconstriction (GO:0042310) | 1/30 | 0.4704044 | 1 | 0 | 0 | 1.5910899 | 1.1999403 | EDN2 |
| 723 | photoreceptor cell maintenance (GO:0045494) | 1/30 | 0.4704044 | 1 | 0 | 0 | 1.5910899 | 1.1999403 | PCDH15 |
| 724 | replacement ossification (GO:0036075) | 1/30 | 0.4704044 | 1 | 0 | 0 | 1.5910899 | 1.1999403 | PTHLH |
| 725 | regulation of muscle cell differentiation (GO:0051147) | 3/122 | 0.4723536 | 1 | 0 | 0 | 1.1737548 | 0.8803484 | CEACAM5;CDH15;MYLK3 |
| 726 | positive regulation of protein complex assembly (GO:0031334) | 3/122 | 0.4723536 | 1 | 0 | 0 | 1.1737548 | 0.8803484 | CCL24;CSF3;CDC42EP5 |
| 727 | regulation of actin polymerization or depolymerization (GO:0008064) | 3/122 | 0.4723536 | 1 | 0 | 0 | 1.1737548 | 0.8803484 | CCL24;CSF3;CDC42EP5 |
| 728 | myeloid leukocyte migration (GO:0097529) | 2/76 | 0.4749320 | 1 | 0 | 0 | 1.2561236 | 0.9352892 | CCL24;EDN2 |
| 729 | regulation of actin filament length (GO:0030832) | 3/123 | 0.4777203 | 1 | 0 | 0 | 1.1642121 | 0.8600382 | CCL24;CSF3;CDC42EP5 |
| 730 | regulation of endothelial cell apoptotic process (GO:2000351) | 1/31 | 0.4815161 | 1 | 0 | 0 | 1.5397644 | 1.1252839 | THBS1 |
| 731 | phenol-containing compound biosynthetic process (GO:0046189) | 1/31 | 0.4815161 | 1 | 0 | 0 | 1.5397644 | 1.1252839 | GPR37 |
| 732 | cellular response to glucocorticoid stimulus (GO:0071385) | 1/31 | 0.4815161 | 1 | 0 | 0 | 1.5397644 | 1.1252839 | STC1 |
| 733 | protein kinase B signaling (GO:0043491) | 1/31 | 0.4815161 | 1 | 0 | 0 | 1.5397644 | 1.1252839 | NKX3-1 |
| 734 | regulation of mitochondrial membrane potential (GO:0051881) | 1/31 | 0.4815161 | 1 | 0 | 0 | 1.5397644 | 1.1252839 | PYCR1 |
| 735 | positive regulation of blood pressure (GO:0045777) | 1/31 | 0.4815161 | 1 | 0 | 0 | 1.5397644 | 1.1252839 | HSD11B2 |
| 736 | negative regulation of interleukin-6 production (GO:0032715) | 1/31 | 0.4815161 | 1 | 0 | 0 | 1.5397644 | 1.1252839 | IRAK3 |
| 737 | peptide cross-linking (GO:0018149) | 1/31 | 0.4815161 | 1 | 0 | 0 | 1.5397644 | 1.1252839 | THBS1 |
| 738 | regulation of steroid metabolic process (GO:0019218) | 2/77 | 0.4817632 | 1 | 0 | 0 | 1.2398103 | 0.9054366 | APOB;CYP17A1 |
| 739 | positive regulation of transmembrane transport (GO:0034764) | 2/77 | 0.4817632 | 1 | 0 | 0 | 1.2398103 | 0.9054366 | JPH2;STC1 |
| 740 | regulation of calcium ion transport (GO:0051924) | 4/171 | 0.4828810 | 1 | 0 | 0 | 1.1165543 | 0.8128349 | JPH2;STC1;PTGS2;ADRA2A |
| 741 | signal release (GO:0023061) | 3/124 | 0.4830616 | 1 | 0 | 0 | 1.1548233 | 0.8402623 | ADORA3;DOC2B;SLC6A1 |
| 742 | anion transmembrane transport (GO:0098656) | 4/172 | 0.4874009 | 1 | 0 | 0 | 1.1100627 | 0.7977670 | ANO1;SLC26A2;ANO7;SLC13A5 |
| 743 | positive regulation of leukocyte mediated immunity (GO:0002705) | 2/78 | 0.4885395 | 1 | 0 | 0 | 1.2239153 | 0.8767333 | AZGP1;ADORA3 |
| 744 | regulation of tumor necrosis factor production (GO:0032680) | 2/78 | 0.4885395 | 1 | 0 | 0 | 1.2239153 | 0.8767333 | IRAK3;THBS1 |
| 745 | cellular response to lipid (GO:0071396) | 7/315 | 0.4907568 | 1 | 0 | 0 | 1.0607266 | 0.7550323 | CSF3;MUC1;BRINP1;STC1;APOB;CYP17A1;NKX3-1 |
| 746 | regulation of ossification (GO:0030278) | 4/173 | 0.4919047 | 1 | 0 | 0 | 1.1036462 | 0.7830041 | FBN2;AHSG;ZBTB16;CTHRC1 |
| 747 | pteridine-containing compound metabolic process (GO:0042558) | 1/32 | 0.4923952 | 1 | 0 | 0 | 1.4916468 | 1.0567925 | ALDH1L2 |
| 748 | regulation of intrinsic apoptotic signaling pathway in response to DNA damage (GO:1902229) | 1/32 | 0.4923952 | 1 | 0 | 0 | 1.4916468 | 1.0567925 | MUC1 |
| 749 | reproduction (GO:0000003) | 1/32 | 0.4923952 | 1 | 0 | 0 | 1.4916468 | 1.0567925 | CATSPERB |
| 750 | positive regulation of protein tyrosine kinase activity (GO:0061098) | 1/32 | 0.4923952 | 1 | 0 | 0 | 1.4916468 | 1.0567925 | ADRA2A |
| 751 | positive regulation of nitric oxide biosynthetic process (GO:0045429) | 1/32 | 0.4923952 | 1 | 0 | 0 | 1.4916468 | 1.0567925 | PTGS2 |
| 752 | rhythmic behavior (GO:0007622) | 1/32 | 0.4923952 | 1 | 0 | 0 | 1.4916468 | 1.0567925 | SIX3 |
| 753 | regulation of potassium ion transmembrane transport (GO:1901379) | 1/32 | 0.4923952 | 1 | 0 | 0 | 1.4916468 | 1.0567925 | KCNN2 |
| 754 | brown fat cell differentiation (GO:0050873) | 1/32 | 0.4923952 | 1 | 0 | 0 | 1.4916468 | 1.0567925 | PTGS2 |
| 755 | calcium ion import (GO:0070509) | 1/32 | 0.4923952 | 1 | 0 | 0 | 1.4916468 | 1.0567925 | CACNA1E |
| 756 | response to pain (GO:0048265) | 1/32 | 0.4923952 | 1 | 0 | 0 | 1.4916468 | 1.0567925 | THBS1 |
| 757 | negative regulation of purine nucleotide catabolic process (GO:0033122) | 1/32 | 0.4923952 | 1 | 0 | 0 | 1.4916468 | 1.0567925 | TNNI3 |
| 758 | androgen metabolic process (GO:0008209) | 1/32 | 0.4923952 | 1 | 0 | 0 | 1.4916468 | 1.0567925 | CYP17A1 |
| 759 | one-carbon metabolic process (GO:0006730) | 1/32 | 0.4923952 | 1 | 0 | 0 | 1.4916468 | 1.0567925 | ALDH1L2 |
| 760 | sulfur compound transport (GO:0072348) | 1/32 | 0.4923952 | 1 | 0 | 0 | 1.4916468 | 1.0567925 | SLC26A2 |
| 761 | regulation of synaptic transmission, GABAergic (GO:0032228) | 1/32 | 0.4923952 | 1 | 0 | 0 | 1.4916468 | 1.0567925 | SLC6A1 |
| 762 | regulation of intrinsic apoptotic signaling pathway (GO:2001242) | 3/126 | 0.4936654 | 1 | 0 | 0 | 1.1364928 | 0.8022473 | MUC1;IL19;NKX3-1 |
| 763 | eye development (GO:0001654) | 2/79 | 0.4952601 | 1 | 0 | 0 | 1.2084227 | 0.8491250 | SIX3;PAX6 |
| 764 | positive regulation of epithelial cell migration (GO:0010634) | 2/79 | 0.4952601 | 1 | 0 | 0 | 1.2084227 | 0.8491250 | PTGS2;THBS1 |
| 765 | regulation of protein polymerization (GO:0032271) | 3/127 | 0.4989268 | 1 | 0 | 0 | 1.1275440 | 0.7839768 | CCL24;CSF3;CDC42EP5 |
| 766 | inorganic anion transport (GO:0015698) | 3/127 | 0.4989268 | 1 | 0 | 0 | 1.1275440 | 0.7839768 | ANO1;SLC26A2;ANO7 |
| 767 | positive regulation of protein import into nucleus (GO:0042307) | 2/80 | 0.5019244 | 1 | 0 | 0 | 1.1933174 | 0.8225606 | CSF3;PTGS2 |
| 768 | regulation of tumor necrosis factor superfamily cytokine production (GO:1903555) | 2/80 | 0.5019244 | 1 | 0 | 0 | 1.1933174 | 0.8225606 | IRAK3;THBS1 |
| 769 | positive regulation of reproductive process (GO:2000243) | 1/33 | 0.5030465 | 1 | 0 | 0 | 1.4464454 | 0.9938131 | PLAT |
| 770 | calcium ion-dependent exocytosis (GO:0017156) | 1/33 | 0.5030465 | 1 | 0 | 0 | 1.4464454 | 0.9938131 | SYT8 |
| 771 | negative regulation of nucleotide catabolic process (GO:0030812) | 1/33 | 0.5030465 | 1 | 0 | 0 | 1.4464454 | 0.9938131 | TNNI3 |
| 772 | peptide hormone processing (GO:0016486) | 1/33 | 0.5030465 | 1 | 0 | 0 | 1.4464454 | 0.9938131 | CPE |
| 773 | cellular response to corticosteroid stimulus (GO:0071384) | 1/33 | 0.5030465 | 1 | 0 | 0 | 1.4464454 | 0.9938131 | STC1 |
| 774 | regulation of insulin secretion involved in cellular response to glucose stimulus (GO:0061178) | 1/33 | 0.5030465 | 1 | 0 | 0 | 1.4464454 | 0.9938131 | ADRA2A |
| 775 | response to progesterone (GO:0032570) | 1/33 | 0.5030465 | 1 | 0 | 0 | 1.4464454 | 0.9938131 | THBS1 |
| 776 | transferrin transport (GO:0033572) | 1/33 | 0.5030465 | 1 | 0 | 0 | 1.4464454 | 0.9938131 | REP15 |
| 777 | regulation of protein binding (GO:0043393) | 3/128 | 0.5041604 | 1 | 0 | 0 | 1.1187351 | 0.7661777 | CSF3;NKX3-1;CTHRC1 |
| 778 | response to mechanical stimulus (GO:0009612) | 4/176 | 0.5053159 | 1 | 0 | 0 | 1.0848340 | 0.7404767 | NTRK2;PCDH15;PTGS2;THBS1 |
| 779 | secretion by cell (GO:0032940) | 9/415 | 0.5053996 | 1 | 0 | 0 | 1.0351669 | 0.7064041 | NTRK2;SLC17A9;ADORA3;DOC2B;SLC6A1;SYT8;THBS1;F5;STXBP5L |
| 780 | platelet degranulation (GO:0002576) | 2/81 | 0.5085318 | 1 | 0 | 0 | 1.1785851 | 0.7969918 | THBS1;F5 |
| 781 | regulation of epithelial cell migration (GO:0010632) | 3/129 | 0.5093659 | 1 | 0 | 0 | 1.1100627 | 0.7488358 | STC1;PTGS2;THBS1 |
| 782 | negative regulation of reproductive process (GO:2000242) | 1/34 | 0.5134749 | 1 | 0 | 0 | 1.4039028 | 0.9357774 | NKX3-1 |
| 783 | response to cocaine (GO:0042220) | 1/34 | 0.5134749 | 1 | 0 | 0 | 1.4039028 | 0.9357774 | SLC6A1 |
| 784 | regulation of cholesterol transport (GO:0032374) | 1/34 | 0.5134749 | 1 | 0 | 0 | 1.4039028 | 0.9357774 | LIPG |
| 785 | regulation of sterol transport (GO:0032371) | 1/34 | 0.5134749 | 1 | 0 | 0 | 1.4039028 | 0.9357774 | LIPG |
| 786 | negative regulation of tumor necrosis factor production (GO:0032720) | 1/34 | 0.5134749 | 1 | 0 | 0 | 1.4039028 | 0.9357774 | IRAK3 |
| 787 | positive regulation of T cell mediated immunity (GO:0002711) | 1/34 | 0.5134749 | 1 | 0 | 0 | 1.4039028 | 0.9357774 | AZGP1 |
| 788 | neuron fate commitment (GO:0048663) | 1/34 | 0.5134749 | 1 | 0 | 0 | 1.4039028 | 0.9357774 | PAX6 |
| 789 | neuromuscular junction development (GO:0007528) | 1/34 | 0.5134749 | 1 | 0 | 0 | 1.4039028 | 0.9357774 | NTRK2 |
| 790 | G2 DNA damage checkpoint (GO:0031572) | 1/34 | 0.5134749 | 1 | 0 | 0 | 1.4039028 | 0.9357774 | NEK6 |
| 791 | regulation of dendritic spine development (GO:0060998) | 1/34 | 0.5134749 | 1 | 0 | 0 | 1.4039028 | 0.9357774 | CUX2 |
| 792 | positive regulation of bone mineralization (GO:0030501) | 1/34 | 0.5134749 | 1 | 0 | 0 | 1.4039028 | 0.9357774 | FBN2 |
| 793 | response to alcohol (GO:0097305) | 6/274 | 0.5139041 | 1 | 0 | 0 | 1.0452415 | 0.6958368 | STC1;TFF1;SLC6A1;PTGS2;THBS1;NKX3-1 |
| 794 | regulation of system process (GO:0044057) | 8/371 | 0.5170404 | 1 | 0 | 0 | 1.0292765 | 0.6789460 | C1QTNF1;EDN2;ADORA3;STC1;TNNI3;PTGS2;ADRA2A;NKX3-1 |
| 795 | cognition (GO:0050890) | 5/227 | 0.5178823 | 1 | 0 | 0 | 1.0513810 | 0.6918163 | NTRK2;CUX2;CHRM1;SLC6A1;PTGS2 |
| 796 | regulation of angiogenesis (GO:0045765) | 4/179 | 0.5185687 | 1 | 0 | 0 | 1.0666524 | 0.7004524 | CCL24;ADM2;PTGS2;THBS1 |
| 797 | positive regulation of intracellular protein transport (GO:0090316) | 3/131 | 0.5196902 | 1 | 0 | 0 | 1.0931152 | 0.7154685 | CSF3;CHRM1;PTGS2 |
| 798 | response to lipopolysaccharide (GO:0032496) | 5/228 | 0.5217758 | 1 | 0 | 0 | 1.0467697 | 0.6809418 | CSF3;IRAK3;APOB;PTGS2;CYP17A1 |
| 799 | ferric iron transport (GO:0015682) | 1/35 | 0.5236849 | 1 | 0 | 0 | 1.3637913 | 0.8821891 | REP15 |
| 800 | drug metabolic process (GO:0017144) | 1/35 | 0.5236849 | 1 | 0 | 0 | 1.3637913 | 0.8821891 | CYP3A5 |
| 801 | positive regulation of neural precursor cell proliferation (GO:2000179) | 1/35 | 0.5236849 | 1 | 0 | 0 | 1.3637913 | 0.8821891 | PAX6 |
| 802 | metanephros development (GO:0001656) | 1/35 | 0.5236849 | 1 | 0 | 0 | 1.3637913 | 0.8821891 | NKX3-1 |
| 803 | negative regulation of tumor necrosis factor superfamily cytokine production (GO:1903556) | 1/35 | 0.5236849 | 1 | 0 | 0 | 1.3637913 | 0.8821891 | IRAK3 |
| 804 | negative regulation of ion transmembrane transporter activity (GO:0032413) | 1/35 | 0.5236849 | 1 | 0 | 0 | 1.3637913 | 0.8821891 | ADRA2A |
| 805 | positive regulation of phagocytosis (GO:0050766) | 1/35 | 0.5236849 | 1 | 0 | 0 | 1.3637913 | 0.8821891 | AHSG |
| 806 | positive regulation of alpha-beta T cell differentiation (GO:0046638) | 1/35 | 0.5236849 | 1 | 0 | 0 | 1.3637913 | 0.8821891 | ZBTB16 |
| 807 | negative regulation of nucleoside metabolic process (GO:0045978) | 1/35 | 0.5236849 | 1 | 0 | 0 | 1.3637913 | 0.8821891 | TNNI3 |
| 808 | glycoprotein biosynthetic process (GO:0009101) | 1/35 | 0.5236849 | 1 | 0 | 0 | 1.3637913 | 0.8821891 | B3GNT6 |
| 809 | cAMP metabolic process (GO:0046058) | 1/35 | 0.5236849 | 1 | 0 | 0 | 1.3637913 | 0.8821891 | PTHLH |
| 810 | trivalent inorganic cation transport (GO:0072512) | 1/35 | 0.5236849 | 1 | 0 | 0 | 1.3637913 | 0.8821891 | REP15 |
| 811 | hexose catabolic process (GO:0019320) | 1/35 | 0.5236849 | 1 | 0 | 0 | 1.3637913 | 0.8821891 | FUT6 |
| 812 | protein trimerization (GO:0070206) | 1/35 | 0.5236849 | 1 | 0 | 0 | 1.3637913 | 0.8821891 | C1QTNF1 |
| 813 | positive regulation of protein localization to nucleus (GO:1900182) | 2/84 | 0.5280072 | 1 | 0 | 0 | 1.1364928 | 0.7258159 | CSF3;PTGS2 |
| 814 | chloride transmembrane transport (GO:1902476) | 2/84 | 0.5280072 | 1 | 0 | 0 | 1.1364928 | 0.7258159 | ANO1;ANO7 |
| 815 | negative regulation of peptidase activity (GO:0010466) | 5/230 | 0.5295221 | 1 | 0 | 0 | 1.0376673 | 0.6597285 | SERPINB4;AHSG;HMSD;SSPO;THBS1 |
| 816 | positive regulation of protein transport (GO:0051222) | 5/231 | 0.5333744 | 1 | 0 | 0 | 1.0331753 | 0.6493833 | CSF3;CHRM1;PTGS2;ALOX15B;STXBP5L |
| 817 | regulation of cell-substrate junction assembly (GO:0090109) | 1/36 | 0.5336812 | 1 | 0 | 0 | 1.3259082 | 0.8326130 | THBS1 |
| 818 | detection of chemical stimulus involved in sensory perception of bitter taste (GO:0001580) | 1/36 | 0.5336812 | 1 | 0 | 0 | 1.3259082 | 0.8326130 | AZGP1 |
| 819 | regulation of insulin receptor signaling pathway (GO:0046626) | 1/36 | 0.5336812 | 1 | 0 | 0 | 1.3259082 | 0.8326130 | AHSG |
| 820 | regulation of histone acetylation (GO:0035065) | 1/36 | 0.5336812 | 1 | 0 | 0 | 1.3259082 | 0.8326130 | MUC1 |
| 821 | regulation of focal adhesion assembly (GO:0051893) | 1/36 | 0.5336812 | 1 | 0 | 0 | 1.3259082 | 0.8326130 | THBS1 |
| 822 | regulation of catecholamine secretion (GO:0050433) | 1/36 | 0.5336812 | 1 | 0 | 0 | 1.3259082 | 0.8326130 | ADRA2A |
| 823 | synaptic transmission, glutamatergic (GO:0035249) | 1/36 | 0.5336812 | 1 | 0 | 0 | 1.3259082 | 0.8326130 | PLAT |
| 824 | positive regulation of biomineral tissue development (GO:0070169) | 1/36 | 0.5336812 | 1 | 0 | 0 | 1.3259082 | 0.8326130 | FBN2 |
| 825 | positive regulation of synaptic transmission (GO:0050806) | 2/85 | 0.5343819 | 1 | 0 | 0 | 1.1231223 | 0.7037984 | NTRK2;PTGS2 |
| 826 | blood vessel development (GO:0001568) | 2/85 | 0.5343819 | 1 | 0 | 0 | 1.1231223 | 0.7037984 | PAX6;NKX3-1 |
| 827 | regulation of striated muscle cell differentiation (GO:0051153) | 2/85 | 0.5343819 | 1 | 0 | 0 | 1.1231223 | 0.7037984 | CEACAM5;MYLK3 |
| 828 | second-messenger-mediated signaling (GO:0019932) | 3/134 | 0.5349533 | 1 | 0 | 0 | 1.0686425 | 0.6685170 | NTRK2;EDN2;BHLHA15 |
| 829 | positive regulation of cell migration (GO:0030335) | 6/280 | 0.5350561 | 1 | 0 | 0 | 1.0228435 | 0.6396697 | CCL24;EDN2;ADORA3;PTGS2;THBS1;ADRA2A |
| 830 | negative regulation of secretion by cell (GO:1903531) | 3/135 | 0.5399797 | 1 | 0 | 0 | 1.0607266 | 0.6536449 | BMP8A;ADRA2A;STXBP5L |
| 831 | regulation of reproductive process (GO:2000241) | 2/86 | 0.5406975 | 1 | 0 | 0 | 1.1100627 | 0.6825724 | PLAT;NKX3-1 |
| 832 | embryonic limb morphogenesis (GO:0030326) | 2/86 | 0.5406975 | 1 | 0 | 0 | 1.1100627 | 0.6825724 | FBN2;ZBTB16 |
| 833 | regulation of stem cell proliferation (GO:0072091) | 2/86 | 0.5406975 | 1 | 0 | 0 | 1.1100627 | 0.6825724 | SIX3;PAX6 |
| 834 | long-chain fatty acid metabolic process (GO:0001676) | 2/86 | 0.5406975 | 1 | 0 | 0 | 1.1100627 | 0.6825724 | PTGS2;ALOX15B |
| 835 | vascular process in circulatory system (GO:0003018) | 2/86 | 0.5406975 | 1 | 0 | 0 | 1.1100627 | 0.6825724 | EDN2;MYLK3 |
| 836 | embryonic appendage morphogenesis (GO:0035113) | 2/86 | 0.5406975 | 1 | 0 | 0 | 1.1100627 | 0.6825724 | FBN2;ZBTB16 |
| 837 | exocytosis (GO:0006887) | 5/233 | 0.5410362 | 1 | 0 | 0 | 1.0243068 | 0.6292000 | SLC17A9;SYT8;THBS1;F5;STXBP5L |
| 838 | mitotic nuclear envelope disassembly (GO:0007077) | 1/37 | 0.5434681 | 1 | 0 | 0 | 1.2900729 | 0.7866661 | NEK6 |
| 839 | regulation of epidermal cell differentiation (GO:0045604) | 1/37 | 0.5434681 | 1 | 0 | 0 | 1.2900729 | 0.7866661 | ALOX15B |
| 840 | positive regulation of leukocyte mediated cytotoxicity (GO:0001912) | 1/37 | 0.5434681 | 1 | 0 | 0 | 1.2900729 | 0.7866661 | AZGP1 |
| 841 | regulation of toll-like receptor signaling pathway (GO:0034121) | 1/37 | 0.5434681 | 1 | 0 | 0 | 1.2900729 | 0.7866661 | IRAK3 |
| 842 | regulation of adherens junction organization (GO:1903391) | 1/37 | 0.5434681 | 1 | 0 | 0 | 1.2900729 | 0.7866661 | THBS1 |
| 843 | feeding behavior (GO:0007631) | 2/87 | 0.5469535 | 1 | 0 | 0 | 1.0973034 | 0.6621035 | NTRK2;ADM2 |
| 844 | regulation of fat cell differentiation (GO:0045598) | 2/87 | 0.5469535 | 1 | 0 | 0 | 1.0973034 | 0.6621035 | ZBTB16;PTGS2 |
| 845 | dicarboxylic acid metabolic process (GO:0043648) | 2/87 | 0.5469535 | 1 | 0 | 0 | 1.0973034 | 0.6621035 | ALDH1L2;CYP17A1 |
| 846 | adult walking behavior (GO:0007628) | 1/38 | 0.5530502 | 1 | 0 | 0 | 1.2561236 | 0.7440102 | PCDH15 |
| 847 | epithelial cell morphogenesis (GO:0003382) | 1/38 | 0.5530502 | 1 | 0 | 0 | 1.2561236 | 0.7440102 | STC1 |
| 848 | muscle filament sliding (GO:0030049) | 1/38 | 0.5530502 | 1 | 0 | 0 | 1.2561236 | 0.7440102 | TNNI3 |
| 849 | protein kinase C-activating G-protein coupled receptor signaling pathway (GO:0007205) | 1/38 | 0.5530502 | 1 | 0 | 0 | 1.2561236 | 0.7440102 | CHRM1 |
| 850 | membrane depolarization during action potential (GO:0086010) | 1/38 | 0.5530502 | 1 | 0 | 0 | 1.2561236 | 0.7440102 | CACNA1E |
| 851 | hindlimb morphogenesis (GO:0035137) | 1/38 | 0.5530502 | 1 | 0 | 0 | 1.2561236 | 0.7440102 | ZBTB16 |
| 852 | anion homeostasis (GO:0055081) | 1/38 | 0.5530502 | 1 | 0 | 0 | 1.2561236 | 0.7440102 | LIPG |
| 853 | regulation of calcium-mediated signaling (GO:0050848) | 1/38 | 0.5530502 | 1 | 0 | 0 | 1.2561236 | 0.7440102 | ADORA3 |
| 854 | regulation of lipid storage (GO:0010883) | 1/38 | 0.5530502 | 1 | 0 | 0 | 1.2561236 | 0.7440102 | APOB |
| 855 | ventricular cardiac muscle tissue morphogenesis (GO:0055010) | 1/38 | 0.5530502 | 1 | 0 | 0 | 1.2561236 | 0.7440102 | TNNI3 |
| 856 | positive regulation of oxidoreductase activity (GO:0051353) | 1/38 | 0.5530502 | 1 | 0 | 0 | 1.2561236 | 0.7440102 | EDN2 |
| 857 | actin-myosin filament sliding (GO:0033275) | 1/38 | 0.5530502 | 1 | 0 | 0 | 1.2561236 | 0.7440102 | TNNI3 |
| 858 | positive regulation of reactive oxygen species metabolic process (GO:2000379) | 1/38 | 0.5530502 | 1 | 0 | 0 | 1.2561236 | 0.7440102 | THBS1 |
| 859 | regulation of endothelial cell proliferation (GO:0001936) | 2/88 | 0.5531498 | 1 | 0 | 0 | 1.0848340 | 0.6423590 | CCL24;THBS1 |
| 860 | pattern specification process (GO:0007389) | 8/385 | 0.5591631 | 1 | 0 | 0 | 0.9918482 | 0.5765754 | LEFTY1;DAAM2;ZBTB16;SIX3;STC1;PAX6;FEZF1;NKX3-1 |
| 861 | positive regulation of cell motility (GO:2000147) | 6/287 | 0.5592308 | 1 | 0 | 0 | 0.9978961 | 0.5799703 | CCL24;EDN2;ADORA3;PTGS2;THBS1;ADRA2A |
| 862 | cellular response to reactive oxygen species (GO:0034614) | 2/89 | 0.5592860 | 1 | 0 | 0 | 1.0726449 | 0.6233079 | TPO;PXDN |
| 863 | regulation of dendrite development (GO:0050773) | 2/89 | 0.5592860 | 1 | 0 | 0 | 1.0726449 | 0.6233079 | NTRK2;CUX2 |
| 864 | heart morphogenesis (GO:0003007) | 1/39 | 0.5624316 | 1 | 0 | 0 | 1.2239153 | 0.7043459 | LEFTY1 |
| 865 | regulation of multicellular organismal metabolic process (GO:0044246) | 1/39 | 0.5624316 | 1 | 0 | 0 | 1.2239153 | 0.7043459 | BMP8A |
| 866 | retina homeostasis (GO:0001895) | 1/39 | 0.5624316 | 1 | 0 | 0 | 1.2239153 | 0.7043459 | AZGP1 |
| 867 | bile acid metabolic process (GO:0008206) | 1/39 | 0.5624316 | 1 | 0 | 0 | 1.2239153 | 0.7043459 | SLCO1B3 |
| 868 | positive regulation of dendrite development (GO:1900006) | 1/39 | 0.5624316 | 1 | 0 | 0 | 1.2239153 | 0.7043459 | CUX2 |
| 869 | endocrine pancreas development (GO:0031018) | 1/39 | 0.5624316 | 1 | 0 | 0 | 1.2239153 | 0.7043459 | FOXA3 |
| 870 | positive regulation of striated muscle cell differentiation (GO:0051155) | 1/39 | 0.5624316 | 1 | 0 | 0 | 1.2239153 | 0.7043459 | MYLK3 |
| 871 | phagosome maturation (GO:0090382) | 1/39 | 0.5624316 | 1 | 0 | 0 | 1.2239153 | 0.7043459 | RAB43 |
| 872 | membrane disassembly (GO:0030397) | 1/39 | 0.5624316 | 1 | 0 | 0 | 1.2239153 | 0.7043459 | NEK6 |
| 873 | hippocampus development (GO:0021766) | 1/39 | 0.5624316 | 1 | 0 | 0 | 1.2239153 | 0.7043459 | CYP17A1 |
| 874 | regulation of NF-kappaB import into nucleus (GO:0042345) | 1/39 | 0.5624316 | 1 | 0 | 0 | 1.2239153 | 0.7043459 | PTGS2 |
| 875 | detection of mechanical stimulus (GO:0050982) | 1/39 | 0.5624316 | 1 | 0 | 0 | 1.2239153 | 0.7043459 | PCDH15 |
| 876 | acute-phase response (GO:0006953) | 1/39 | 0.5624316 | 1 | 0 | 0 | 1.2239153 | 0.7043459 | AHSG |
| 877 | nuclear envelope disassembly (GO:0051081) | 1/39 | 0.5624316 | 1 | 0 | 0 | 1.2239153 | 0.7043459 | NEK6 |
| 878 | bone mineralization (GO:0030282) | 1/39 | 0.5624316 | 1 | 0 | 0 | 1.2239153 | 0.7043459 | PTGS2 |
| 879 | negative regulation of blood pressure (GO:0045776) | 1/39 | 0.5624316 | 1 | 0 | 0 | 1.2239153 | 0.7043459 | ADM2 |
| 880 | regulation of vasodilation (GO:0042312) | 1/39 | 0.5624316 | 1 | 0 | 0 | 1.2239153 | 0.7043459 | ADRA2A |
| 881 | spindle assembly (GO:0051225) | 1/39 | 0.5624316 | 1 | 0 | 0 | 1.2239153 | 0.7043459 | NEK6 |
| 882 | neurogenesis (GO:0022008) | 1/39 | 0.5624316 | 1 | 0 | 0 | 1.2239153 | 0.7043459 | OMP |
| 883 | regulation of heart contraction (GO:0008016) | 3/140 | 0.5646363 | 1 | 0 | 0 | 1.0228435 | 0.5846303 | EDN2;ADORA3;STC1 |
| 884 | positive regulation of chemotaxis (GO:0050921) | 2/90 | 0.5653620 | 1 | 0 | 0 | 1.0607266 | 0.6049208 | EDN2;THBS1 |
| 885 | regulation of neurotransmitter levels (GO:0001505) | 2/90 | 0.5653620 | 1 | 0 | 0 | 1.0607266 | 0.6049208 | DOC2B;SLC6A1 |
| 886 | positive regulation of calcium ion transport (GO:0051928) | 2/91 | 0.5713775 | 1 | 0 | 0 | 1.0490703 | 0.5871700 | JPH2;STC1 |
| 887 | regulation of peptidyl-lysine acetylation (GO:2000756) | 1/40 | 0.5716165 | 1 | 0 | 0 | 1.1933174 | 0.6674069 | MUC1 |
| 888 | monosaccharide catabolic process (GO:0046365) | 1/40 | 0.5716165 | 1 | 0 | 0 | 1.1933174 | 0.6674069 | FUT6 |
| 889 | forelimb morphogenesis (GO:0035136) | 1/40 | 0.5716165 | 1 | 0 | 0 | 1.1933174 | 0.6674069 | ZBTB16 |
| 890 | blood circulation (GO:0008015) | 1/40 | 0.5716165 | 1 | 0 | 0 | 1.1933174 | 0.6674069 | F5 |
| 891 | outflow tract morphogenesis (GO:0003151) | 1/40 | 0.5716165 | 1 | 0 | 0 | 1.1933174 | 0.6674069 | THBS1 |
| 892 | glutamate receptor signaling pathway (GO:0007215) | 1/40 | 0.5716165 | 1 | 0 | 0 | 1.1933174 | 0.6674069 | GRM8 |
| 893 | response to nutrient levels (GO:0031667) | 6/291 | 0.5727788 | 1 | 0 | 0 | 0.9841793 | 0.5484395 | HSD11B2;LIPG;STC1;PTGS2;FOXA3;CYP17A1 |
| 894 | chloride transport (GO:0006821) | 2/92 | 0.5773325 | 1 | 0 | 0 | 1.0376673 | 0.5700289 | ANO1;ANO7 |
| 895 | negative regulation of cell-cell adhesion (GO:0022408) | 1/41 | 0.5806091 | 1 | 0 | 0 | 1.1642121 | 0.6329560 | C1QTNF1 |
| 896 | regulation of transcription from RNA polymerase II promoter in response to stress (GO:0043618) | 1/41 | 0.5806091 | 1 | 0 | 0 | 1.1642121 | 0.6329560 | MUC1 |
| 897 | positive regulation of chemokine production (GO:0032722) | 1/41 | 0.5806091 | 1 | 0 | 0 | 1.1642121 | 0.6329560 | ALOX15B |
| 898 | cardiac muscle contraction (GO:0060048) | 1/41 | 0.5806091 | 1 | 0 | 0 | 1.1642121 | 0.6329560 | TNNI3 |
| 899 | regulation of alcohol biosynthetic process (GO:1902930) | 1/41 | 0.5806091 | 1 | 0 | 0 | 1.1642121 | 0.6329560 | APOB |
| 900 | somitogenesis (GO:0001756) | 1/41 | 0.5806091 | 1 | 0 | 0 | 1.1642121 | 0.6329560 | NKX3-1 |
| 901 | protein peptidyl-prolyl isomerization (GO:0000413) | 1/41 | 0.5806091 | 1 | 0 | 0 | 1.1642121 | 0.6329560 | FKBP5 |
| 902 | response to exogenous dsRNA (GO:0043330) | 1/41 | 0.5806091 | 1 | 0 | 0 | 1.1642121 | 0.6329560 | IRAK3 |
| 903 | regulation of synapse assembly (GO:0051963) | 1/41 | 0.5806091 | 1 | 0 | 0 | 1.1642121 | 0.6329560 | CUX2 |
| 904 | negative regulation of muscle cell differentiation (GO:0051148) | 1/41 | 0.5806091 | 1 | 0 | 0 | 1.1642121 | 0.6329560 | CEACAM5 |
| 905 | positive regulation of binding (GO:0051099) | 2/93 | 0.5832269 | 1 | 0 | 0 | 1.0265096 | 0.5534724 | CSF3;CTHRC1 |
| 906 | regulation of synaptic transmission (GO:0050804) | 5/245 | 0.5857120 | 1 | 0 | 0 | 0.9741367 | 0.5210921 | NTRK2;GRM8;PLAT;SLC6A1;PTGS2 |
| 907 | visual perception (GO:0007601) | 4/195 | 0.5862086 | 1 | 0 | 0 | 0.9791322 | 0.5229346 | GRM8;SIX3;PCDH15;PAX6 |
| 908 | positive regulation of nucleocytoplasmic transport (GO:0046824) | 2/94 | 0.5890605 | 1 | 0 | 0 | 1.0155893 | 0.5374767 | CSF3;PTGS2 |
| 909 | negative regulation of cell-substrate adhesion (GO:0010812) | 1/42 | 0.5894134 | 1 | 0 | 0 | 1.1364928 | 0.6007814 | THBS1 |
| 910 | regulation of ATPase activity (GO:0043462) | 1/42 | 0.5894134 | 1 | 0 | 0 | 1.1364928 | 0.6007814 | TNNI3 |
| 911 | calcium ion transport into cytosol (GO:0060402) | 1/42 | 0.5894134 | 1 | 0 | 0 | 1.1364928 | 0.6007814 | JPH2 |
| 912 | positive regulation of cell killing (GO:0031343) | 1/42 | 0.5894134 | 1 | 0 | 0 | 1.1364928 | 0.6007814 | AZGP1 |
| 913 | negative regulation of response to DNA damage stimulus (GO:2001021) | 1/42 | 0.5894134 | 1 | 0 | 0 | 1.1364928 | 0.6007814 | MUC1 |
| 914 | regulation of ATP catabolic process (GO:1903289) | 1/42 | 0.5894134 | 1 | 0 | 0 | 1.1364928 | 0.6007814 | TNNI3 |
| 915 | regulation of alpha-beta T cell differentiation (GO:0046637) | 1/42 | 0.5894134 | 1 | 0 | 0 | 1.1364928 | 0.6007814 | ZBTB16 |
| 916 | regulation of protein acetylation (GO:1901983) | 1/42 | 0.5894134 | 1 | 0 | 0 | 1.1364928 | 0.6007814 | MUC1 |
| 917 | androgen receptor signaling pathway (GO:0030521) | 1/42 | 0.5894134 | 1 | 0 | 0 | 1.1364928 | 0.6007814 | NKX3-1 |
| 918 | positive regulation of cellular component movement (GO:0051272) | 6/296 | 0.5894219 | 1 | 0 | 0 | 0.9675547 | 0.5114620 | CCL24;EDN2;ADORA3;PTGS2;THBS1;ADRA2A |
| 919 | regionalization (GO:0003002) | 5/247 | 0.5929271 | 1 | 0 | 0 | 0.9662489 | 0.5050426 | ZBTB16;SIX3;PAX6;FEZF1;NKX3-1 |
| 920 | regulation of vasculature development (GO:1901342) | 4/197 | 0.5942693 | 1 | 0 | 0 | 0.9691918 | 0.5043894 | CCL24;ADM2;PTGS2;THBS1 |
| 921 | response to hydrogen peroxide (GO:0042542) | 2/95 | 0.5948333 | 1 | 0 | 0 | 1.0048989 | 0.5220190 | TPO;PXDN |
| 922 | hemopoiesis (GO:0030097) | 2/95 | 0.5948333 | 1 | 0 | 0 | 1.0048989 | 0.5220190 | TPO;ZBTB16 |
| 923 | regulation of cytokine-mediated signaling pathway (GO:0001959) | 2/95 | 0.5948333 | 1 | 0 | 0 | 1.0048989 | 0.5220190 | PXDN;IRAK3 |
| 924 | cellular response to acid chemical (GO:0071229) | 3/147 | 0.5977683 | 1 | 0 | 0 | 0.9741367 | 0.5012440 | MUC1;BRINP1;APOB |
| 925 | detection of chemical stimulus involved in sensory perception of taste (GO:0050912) | 1/43 | 0.5980332 | 1 | 0 | 0 | 1.1100627 | 0.5706932 | AZGP1 |
| 926 | cerebral cortex development (GO:0021987) | 1/43 | 0.5980332 | 1 | 0 | 0 | 1.1100627 | 0.5706932 | NTRK2 |
| 927 | cellular response to cAMP (GO:0071320) | 1/43 | 0.5980332 | 1 | 0 | 0 | 1.1100627 | 0.5706932 | STC1 |
| 928 | catecholamine metabolic process (GO:0006584) | 1/43 | 0.5980332 | 1 | 0 | 0 | 1.1100627 | 0.5706932 | GPR37 |
| 929 | cytosolic calcium ion transport (GO:0060401) | 1/43 | 0.5980332 | 1 | 0 | 0 | 1.1100627 | 0.5706932 | JPH2 |
| 930 | negative regulation of transporter activity (GO:0032410) | 1/43 | 0.5980332 | 1 | 0 | 0 | 1.1100627 | 0.5706932 | ADRA2A |
| 931 | catechol-containing compound metabolic process (GO:0009712) | 1/43 | 0.5980332 | 1 | 0 | 0 | 1.1100627 | 0.5706932 | GPR37 |
| 932 | regulation of cardiac muscle contraction (GO:0055117) | 1/43 | 0.5980332 | 1 | 0 | 0 | 1.1100627 | 0.5706932 | STC1 |
| 933 | sperm motility (GO:0030317) | 1/43 | 0.5980332 | 1 | 0 | 0 | 1.1100627 | 0.5706932 | APOB |
| 934 | learning or memory (GO:0007611) | 4/198 | 0.5982647 | 1 | 0 | 0 | 0.9642969 | 0.4953806 | NTRK2;CUX2;SLC6A1;PTGS2 |
| 935 | sensory perception of light stimulus (GO:0050953) | 4/198 | 0.5982647 | 1 | 0 | 0 | 0.9642969 | 0.4953806 | GRM8;SIX3;PCDH15;PAX6 |
| 936 | positive regulation of cellular component biogenesis (GO:0044089) | 5/249 | 0.6000726 | 1 | 0 | 0 | 0.9584879 | 0.4895042 | CCL24;CSF3;CUX2;CDC42EP5;MYLK3 |
| 937 | lipid homeostasis (GO:0055088) | 2/96 | 0.6005453 | 1 | 0 | 0 | 0.9944312 | 0.5070776 | LIPG;APOB |
| 938 | regulation of metal ion transport (GO:0010959) | 5/250 | 0.6036188 | 1 | 0 | 0 | 0.9546539 | 0.4819212 | JPH2;STC1;KCNN2;PTGS2;ADRA2A |
| 939 | negative regulation of extrinsic apoptotic signaling pathway (GO:2001237) | 2/97 | 0.6061965 | 1 | 0 | 0 | 0.9841793 | 0.4926321 | IL19;THBS1 |
| 940 | glycolytic process (GO:0006096) | 1/44 | 0.6064726 | 1 | 0 | 0 | 1.0848340 | 0.5425209 | HKDC1 |
| 941 | regulation of mitotic metaphase/anaphase transition (GO:0030071) | 1/44 | 0.6064726 | 1 | 0 | 0 | 1.0848340 | 0.5425209 | NEK6 |
| 942 | regulation of lipid catabolic process (GO:0050994) | 1/44 | 0.6064726 | 1 | 0 | 0 | 1.0848340 | 0.5425209 | ADRA2A |
| 943 | positive regulation of tumor necrosis factor production (GO:0032760) | 1/44 | 0.6064726 | 1 | 0 | 0 | 1.0848340 | 0.5425209 | THBS1 |
| 944 | lipoprotein metabolic process (GO:0042157) | 1/44 | 0.6064726 | 1 | 0 | 0 | 1.0848340 | 0.5425209 | APOB |
| 945 | regulation of signal transduction by p53 class mediator (GO:1901796) | 1/44 | 0.6064726 | 1 | 0 | 0 | 1.0848340 | 0.5425209 | MUC1 |
| 946 | regulation of nitric oxide biosynthetic process (GO:0045428) | 1/44 | 0.6064726 | 1 | 0 | 0 | 1.0848340 | 0.5425209 | PTGS2 |
| 947 | regulation of leukocyte mediated cytotoxicity (GO:0001910) | 1/44 | 0.6064726 | 1 | 0 | 0 | 1.0848340 | 0.5425209 | AZGP1 |
| 948 | segmentation (GO:0035282) | 1/44 | 0.6064726 | 1 | 0 | 0 | 1.0848340 | 0.5425209 | NKX3-1 |
| 949 | cell fate determination (GO:0001709) | 1/44 | 0.6064726 | 1 | 0 | 0 | 1.0848340 | 0.5425209 | PAX6 |
| 950 | protein transmembrane transport (GO:0071806) | 1/44 | 0.6064726 | 1 | 0 | 0 | 1.0848340 | 0.5425209 | AZGP1 |
| 951 | multicellular organismal homeostasis (GO:0048871) | 1/44 | 0.6064726 | 1 | 0 | 0 | 1.0848340 | 0.5425209 | EDN2 |
| 952 | neutrophil chemotaxis (GO:0030593) | 1/44 | 0.6064726 | 1 | 0 | 0 | 1.0848340 | 0.5425209 | EDN2 |
| 953 | negative regulation of proteolysis (GO:0045861) | 6/302 | 0.6089415 | 1 | 0 | 0 | 0.9483317 | 0.4704039 | SERPINB4;AHSG;HMSD;SSPO;PLAT;THBS1 |
| 954 | protein processing (GO:0016485) | 4/201 | 0.6101088 | 1 | 0 | 0 | 0.9499044 | 0.4693648 | CPE;PLAT;PTHLH;NKX3-1 |
| 955 | actin filament bundle assembly (GO:0051017) | 1/45 | 0.6147351 | 1 | 0 | 0 | 1.0607266 | 0.5161112 | SHROOM1 |
| 956 | eye morphogenesis (GO:0048592) | 1/45 | 0.6147351 | 1 | 0 | 0 | 1.0607266 | 0.5161112 | PAX6 |
| 957 | regulation of extrinsic apoptotic signaling pathway via death domain receptors (GO:1902041) | 1/45 | 0.6147351 | 1 | 0 | 0 | 1.0607266 | 0.5161112 | THBS1 |
| 958 | regulation of metaphase/anaphase transition of cell cycle (GO:1902099) | 1/45 | 0.6147351 | 1 | 0 | 0 | 1.0607266 | 0.5161112 | NEK6 |
| 959 | response to antibiotic (GO:0046677) | 1/45 | 0.6147351 | 1 | 0 | 0 | 1.0607266 | 0.5161112 | CYP17A1 |
| 960 | positive regulation of ion transmembrane transporter activity (GO:0032414) | 1/45 | 0.6147351 | 1 | 0 | 0 | 1.0607266 | 0.5161112 | JPH2 |
| 961 | neutrophil migration (GO:1990266) | 1/45 | 0.6147351 | 1 | 0 | 0 | 1.0607266 | 0.5161112 | EDN2 |
| 962 | regulation of cellular response to insulin stimulus (GO:1900076) | 1/45 | 0.6147351 | 1 | 0 | 0 | 1.0607266 | 0.5161112 | AHSG |
| 963 | actin filament bundle organization (GO:0061572) | 1/45 | 0.6147351 | 1 | 0 | 0 | 1.0607266 | 0.5161112 | SHROOM1 |
| 964 | positive regulation of locomotion (GO:0040017) | 6/304 | 0.6153339 | 1 | 0 | 0 | 0.9420927 | 0.4574711 | CCL24;EDN2;ADORA3;PTGS2;THBS1;ADRA2A |
| 965 | neurotransmitter transport (GO:0006836) | 2/99 | 0.6173166 | 1 | 0 | 0 | 0.9642969 | 0.4651511 | DOC2B;SLC6A1 |
| 966 | positive regulation of cytosolic calcium ion concentration (GO:0007204) | 3/152 | 0.6204039 | 1 | 0 | 0 | 0.9420927 | 0.4497405 | JPH2;C1QTNF1;EDN2 |
| 967 | negative regulation of secretion (GO:0051048) | 3/152 | 0.6204039 | 1 | 0 | 0 | 0.9420927 | 0.4497405 | BMP8A;ADRA2A;STXBP5L |
| 968 | cell morphogenesis (GO:0000902) | 4/204 | 0.6217366 | 1 | 0 | 0 | 0.9359352 | 0.4447927 | STC1;TFCP2L1;SHROOM1;WNT16 |
| 969 | cell-matrix adhesion (GO:0007160) | 2/100 | 0.6227857 | 1 | 0 | 0 | 0.9546539 | 0.4520791 | ITGA10;NID2 |
| 970 | sensory perception of chemical stimulus (GO:0007606) | 2/100 | 0.6227857 | 1 | 0 | 0 | 0.9546539 | 0.4520791 | OMP;GRM8 |
| 971 | response to calcium ion (GO:0051592) | 2/100 | 0.6227857 | 1 | 0 | 0 | 0.9546539 | 0.4520791 | SLC6A1;THBS1 |
| 972 | leukocyte chemotaxis (GO:0030595) | 2/100 | 0.6227857 | 1 | 0 | 0 | 0.9546539 | 0.4520791 | CCL24;EDN2 |
| 973 | fertilization (GO:0009566) | 2/100 | 0.6227857 | 1 | 0 | 0 | 0.9546539 | 0.4520791 | CATSPERB;APOB |
| 974 | regulation of T cell mediated immunity (GO:0002709) | 1/46 | 0.6228246 | 1 | 0 | 0 | 1.0376673 | 0.4913255 | AZGP1 |
| 975 | regulation of DNA-templated transcription in response to stress (GO:0043620) | 1/46 | 0.6228246 | 1 | 0 | 0 | 1.0376673 | 0.4913255 | MUC1 |
| 976 | positive regulation of tumor necrosis factor superfamily cytokine production (GO:1903557) | 1/46 | 0.6228246 | 1 | 0 | 0 | 1.0376673 | 0.4913255 | THBS1 |
| 977 | actin-mediated cell contraction (GO:0070252) | 1/46 | 0.6228246 | 1 | 0 | 0 | 1.0376673 | 0.4913255 | TNNI3 |
| 978 | artery morphogenesis (GO:0048844) | 1/46 | 0.6228246 | 1 | 0 | 0 | 1.0376673 | 0.4913255 | APOB |
| 979 | positive regulation of smooth muscle cell proliferation (GO:0048661) | 1/46 | 0.6228246 | 1 | 0 | 0 | 1.0376673 | 0.4913255 | PTGS2 |
| 980 | positive regulation of Rac GTPase activity (GO:0032855) | 1/46 | 0.6228246 | 1 | 0 | 0 | 1.0376673 | 0.4913255 | CCL24 |
| 981 | platelet activation (GO:0030168) | 4/205 | 0.6255638 | 1 | 0 | 0 | 0.9313697 | 0.4369073 | ENTPD2;THBS1;ADRA2A;F5 |
| 982 | regulation of actin filament-based process (GO:0032970) | 5/257 | 0.6279339 | 1 | 0 | 0 | 0.9286517 | 0.4321205 | CCL24;CSF3;CDC42EP5;STC1;MYLK3 |
| 983 | transition metal ion transport (GO:0000041) | 2/101 | 0.6281942 | 1 | 0 | 0 | 0.9452019 | 0.4394299 | TCN1;REP15 |
| 984 | regulation of response to cytokine stimulus (GO:0060759) | 2/101 | 0.6281942 | 1 | 0 | 0 | 0.9452019 | 0.4394299 | PXDN;IRAK3 |
| 985 | limb morphogenesis (GO:0035108) | 2/101 | 0.6281942 | 1 | 0 | 0 | 0.9452019 | 0.4394299 | FBN2;ZBTB16 |
| 986 | appendage morphogenesis (GO:0035107) | 2/101 | 0.6281942 | 1 | 0 | 0 | 0.9452019 | 0.4394299 | FBN2;ZBTB16 |
| 987 | extracellular matrix organization (GO:0030198) | 7/359 | 0.6287802 | 1 | 0 | 0 | 0.9307211 | 0.4318299 | COMP;FBN2;ITGA10;PXDN;NID2;THBS1;MUC5AC |
| 988 | developmental maturation (GO:0021700) | 3/154 | 0.6292124 | 1 | 0 | 0 | 0.9298577 | 0.4307904 | SIX3;BHLHA15;TFCP2L1 |
| 989 | chaperone-mediated protein folding (GO:0061077) | 1/47 | 0.6307446 | 1 | 0 | 0 | 1.0155893 | 0.4680387 | FKBP5 |
| 990 | neural precursor cell proliferation (GO:0061351) | 1/47 | 0.6307446 | 1 | 0 | 0 | 1.0155893 | 0.4680387 | SIX3 |
| 991 | smooth muscle contraction (GO:0006939) | 1/47 | 0.6307446 | 1 | 0 | 0 | 1.0155893 | 0.4680387 | EDN2 |
| 992 | cellular response to UV (GO:0034644) | 1/47 | 0.6307446 | 1 | 0 | 0 | 1.0155893 | 0.4680387 | PTGS2 |
| 993 | acid secretion (GO:0046717) | 1/47 | 0.6307446 | 1 | 0 | 0 | 1.0155893 | 0.4680387 | NTRK2 |
| 994 | extracellular structure organization (GO:0043062) | 7/360 | 0.6316703 | 1 | 0 | 0 | 0.9281358 | 0.4263742 | COMP;FBN2;ITGA10;PXDN;NID2;THBS1;MUC5AC |
| 995 | organic hydroxy compound transport (GO:0015850) | 2/102 | 0.6335424 | 1 | 0 | 0 | 0.9359352 | 0.4271873 | LIPG;APOB |
| 996 | zymogen activation (GO:0031638) | 2/102 | 0.6335424 | 1 | 0 | 0 | 0.9359352 | 0.4271873 | PLAT;NKX3-1 |
| 997 | cell chemotaxis (GO:0060326) | 3/155 | 0.6335636 | 1 | 0 | 0 | 0.9238586 | 0.4216444 | CCL24;EDN2;CXCL2 |
| 998 | anatomical structure homeostasis (GO:0060249) | 4/208 | 0.6368974 | 1 | 0 | 0 | 0.9179365 | 0.4141241 | AZGP1;TFF1;PTHLH;MUC6 |
| 999 | regulation of cardiac muscle tissue development (GO:0055024) | 1/48 | 0.6384987 | 1 | 0 | 0 | 0.9944312 | 0.4461373 | JPH2 |
| 1000 | sperm-egg recognition (GO:0035036) | 1/48 | 0.6384987 | 1 | 0 | 0 | 0.9944312 | 0.4461373 | CATSPERB |
| 1001 | positive regulation of alpha-beta T cell activation (GO:0046635) | 1/48 | 0.6384987 | 1 | 0 | 0 | 0.9944312 | 0.4461373 | ZBTB16 |
| 1002 | phospholipid transport (GO:0015914) | 1/48 | 0.6384987 | 1 | 0 | 0 | 0.9944312 | 0.4461373 | ATP10B |
| 1003 | phagocytosis (GO:0006909) | 1/48 | 0.6384987 | 1 | 0 | 0 | 0.9944312 | 0.4461373 | ELMOD1 |
| 1004 | regulation of transforming growth factor beta receptor signaling pathway (GO:0017015) | 2/103 | 0.6388304 | 1 | 0 | 0 | 0.9268485 | 0.4153359 | FBN2;THBS1 |
| 1005 | sensory organ development (GO:0007423) | 2/103 | 0.6388304 | 1 | 0 | 0 | 0.9268485 | 0.4153359 | SIX3;PAX6 |
| 1006 | positive regulation of lipid metabolic process (GO:0045834) | 2/103 | 0.6388304 | 1 | 0 | 0 | 0.9268485 | 0.4153359 | PTGS2;CYP17A1 |
| 1007 | cellular calcium ion homeostasis (GO:0006874) | 5/261 | 0.6414181 | 1 | 0 | 0 | 0.9144195 | 0.4060697 | JPH2;C1QTNF1;EDN2;STC1;TNNI3 |
| 1008 | response to extracellular stimulus (GO:0009991) | 6/313 | 0.6433621 | 1 | 0 | 0 | 0.9150038 | 0.4035602 | HSD11B2;LIPG;STC1;PTGS2;FOXA3;CYP17A1 |
| 1009 | monocarboxylic acid transport (GO:0015718) | 2/104 | 0.6440582 | 1 | 0 | 0 | 0.9179365 | 0.4038609 | SLCO1B3;SLC6A1 |
| 1010 | negative regulation of cellular response to growth factor stimulus (GO:0090288) | 2/104 | 0.6440582 | 1 | 0 | 0 | 0.9179365 | 0.4038609 | FBN2;THBS1 |
| 1011 | cellular response to drug (GO:0035690) | 1/49 | 0.6460903 | 1 | 0 | 0 | 0.9741367 | 0.4255184 | NKX3-1 |
| 1012 | regulation of cytokine production involved in immune response (GO:0002718) | 1/49 | 0.6460903 | 1 | 0 | 0 | 0.9741367 | 0.4255184 | IRAK3 |
| 1013 | response to dsRNA (GO:0043331) | 1/49 | 0.6460903 | 1 | 0 | 0 | 0.9741367 | 0.4255184 | IRAK3 |
| 1014 | regulation of ion transmembrane transport (GO:0034765) | 6/314 | 0.6463999 | 1 | 0 | 0 | 0.9120897 | 0.3979785 | JPH2;STC1;KCNN2;CACNA1E;THBS1;ADRA2A |
| 1015 | hormone metabolic process (GO:0042445) | 3/158 | 0.6464036 | 1 | 0 | 0 | 0.9063170 | 0.3954544 | TPO;CPE;CYP17A1 |
| 1016 | response to ketone (GO:1901654) | 2/105 | 0.6492262 | 1 | 0 | 0 | 0.9091942 | 0.3927483 | THBS1;NKX3-1 |
| 1017 | negative regulation of protein processing (GO:0010955) | 6/316 | 0.6524286 | 1 | 0 | 0 | 0.9063170 | 0.3870459 | SERPINB4;AHSG;HMSD;SSPO;PLAT;THBS1 |
| 1018 | negative regulation of protein maturation (GO:1903318) | 6/316 | 0.6524286 | 1 | 0 | 0 | 0.9063170 | 0.3870459 | SERPINB4;AHSG;HMSD;SSPO;PLAT;THBS1 |
| 1019 | cardiac muscle tissue morphogenesis (GO:0055008) | 1/50 | 0.6535229 | 1 | 0 | 0 | 0.9546539 | 0.4060885 | TNNI3 |
| 1020 | epithelial to mesenchymal transition (GO:0001837) | 1/50 | 0.6535229 | 1 | 0 | 0 | 0.9546539 | 0.4060885 | WNT16 |
| 1021 | sensory perception of pain (GO:0019233) | 1/50 | 0.6535229 | 1 | 0 | 0 | 0.9546539 | 0.4060885 | PTGS2 |
| 1022 | negative regulation of protein binding (GO:0032091) | 1/50 | 0.6535229 | 1 | 0 | 0 | 0.9546539 | 0.4060885 | NKX3-1 |
| 1023 | regulation of cell killing (GO:0031341) | 1/50 | 0.6535229 | 1 | 0 | 0 | 0.9546539 | 0.4060885 | AZGP1 |
| 1024 | regulation of cell junction assembly (GO:1901888) | 1/50 | 0.6535229 | 1 | 0 | 0 | 0.9546539 | 0.4060885 | THBS1 |
| 1025 | regulation of osteoblast differentiation (GO:0045667) | 2/106 | 0.6543346 | 1 | 0 | 0 | 0.9006169 | 0.3819845 | FBN2;CTHRC1 |
| 1026 | membrane depolarization (GO:0051899) | 2/106 | 0.6543346 | 1 | 0 | 0 | 0.9006169 | 0.3819845 | CUX2;CACNA1E |
| 1027 | positive regulation of protein secretion (GO:0050714) | 2/106 | 0.6543346 | 1 | 0 | 0 | 0.9006169 | 0.3819845 | ALOX15B;STXBP5L |
| 1028 | epithelial cell development (GO:0002064) | 2/107 | 0.6593834 | 1 | 0 | 0 | 0.8921999 | 0.3715567 | PAX6;SPDEF |
| 1029 | positive regulation of behavior (GO:0048520) | 2/107 | 0.6593834 | 1 | 0 | 0 | 0.8921999 | 0.3715567 | EDN2;THBS1 |
| 1030 | response to inorganic substance (GO:0010035) | 7/370 | 0.6598612 | 1 | 0 | 0 | 0.9030510 | 0.3754215 | TPO;PXDN;TFF1;APOB;SLC6A1;PTGS2;THBS1 |
| 1031 | positive regulation of insulin secretion (GO:0032024) | 1/51 | 0.6607998 | 1 | 0 | 0 | 0.9359352 | 0.3877621 | DOC2B |
| 1032 | regulation of neurotransmitter secretion (GO:0046928) | 1/51 | 0.6607998 | 1 | 0 | 0 | 0.9359352 | 0.3877621 | NTRK2 |
| 1033 | positive regulation of axonogenesis (GO:0050772) | 1/51 | 0.6607998 | 1 | 0 | 0 | 0.9359352 | 0.3877621 | NTRK2 |
| 1034 | response to nutrient (GO:0007584) | 3/163 | 0.6670891 | 1 | 0 | 0 | 0.8785159 | 0.3556511 | LIPG;STC1;PTGS2 |
| 1035 | demethylation (GO:0070988) | 1/52 | 0.6679242 | 1 | 0 | 0 | 0.9179365 | 0.3704614 | CYP3A5 |
| 1036 | positive regulation of transporter activity (GO:0032411) | 1/52 | 0.6679242 | 1 | 0 | 0 | 0.9179365 | 0.3704614 | JPH2 |
| 1037 | regulation of excitatory postsynaptic membrane potential (GO:0060079) | 1/52 | 0.6679242 | 1 | 0 | 0 | 0.9179365 | 0.3704614 | CUX2 |
| 1038 | regulation of phagocytosis (GO:0050764) | 1/52 | 0.6679242 | 1 | 0 | 0 | 0.9179365 | 0.3704614 | AHSG |
| 1039 | nuclear envelope organization (GO:0006998) | 1/52 | 0.6679242 | 1 | 0 | 0 | 0.9179365 | 0.3704614 | NEK6 |
| 1040 | regulation of epithelial cell differentiation (GO:0030856) | 2/109 | 0.6693038 | 1 | 0 | 0 | 0.8758293 | 0.3516605 | PAX6;ALOX15B |
| 1041 | positive regulation of intracellular transport (GO:0032388) | 4/217 | 0.6695431 | 1 | 0 | 0 | 0.8798654 | 0.3529666 | CSF3;CHRM1;ADORA3;PTGS2 |
| 1042 | positive regulation of neuron differentiation (GO:0045666) | 4/217 | 0.6695431 | 1 | 0 | 0 | 0.8798654 | 0.3529666 | NTRK2;CUX2;BRINP1;FEZF1 |
| 1043 | cellular divalent inorganic cation homeostasis (GO:0072503) | 5/271 | 0.6737754 | 1 | 0 | 0 | 0.8806771 | 0.3477428 | JPH2;C1QTNF1;EDN2;STC1;TNNI3 |
| 1044 | cellular response to lipopolysaccharide (GO:0071222) | 2/110 | 0.6741759 | 1 | 0 | 0 | 0.8678672 | 0.3421690 | CSF3;CYP17A1 |
| 1045 | regulation of protein tyrosine kinase activity (GO:0061097) | 1/53 | 0.6748993 | 1 | 0 | 0 | 0.9006169 | 0.3541152 | ADRA2A |
| 1046 | regulation of epidermis development (GO:0045682) | 1/53 | 0.6748993 | 1 | 0 | 0 | 0.9006169 | 0.3541152 | ALOX15B |
| 1047 | regulation of cellular component size (GO:0032535) | 3/165 | 0.6751126 | 1 | 0 | 0 | 0.8678672 | 0.3409640 | CCL24;CSF3;CDC42EP5 |
| 1048 | inflammatory response (GO:0006954) | 7/376 | 0.6761377 | 1 | 0 | 0 | 0.8886406 | 0.3477771 | CCL24;AHSG;ADORA3;PTGS2;CXCL2;THBS1;ADRA2A |
| 1049 | response to hexose (GO:0009746) | 2/111 | 0.6789896 | 1 | 0 | 0 | 0.8600486 | 0.3329674 | PTGS2;THBS1 |
| 1050 | response to estrogen (GO:0043627) | 3/166 | 0.6790707 | 1 | 0 | 0 | 0.8626391 | 0.3338672 | TFF1;SLC6A1;PTGS2 |
| 1051 | negative regulation of cell migration (GO:0030336) | 3/166 | 0.6790707 | 1 | 0 | 0 | 0.8626391 | 0.3338672 | STC1;ALOX15B;THBS1 |
| 1052 | regulation of striated muscle contraction (GO:0006942) | 1/54 | 0.6817282 | 1 | 0 | 0 | 0.8839388 | 0.3386584 | STC1 |
| 1053 | monocarboxylic acid biosynthetic process (GO:0072330) | 3/167 | 0.6829931 | 1 | 0 | 0 | 0.8574736 | 0.3269295 | EDN2;PTGS2;ALOX15B |
| 1054 | response to wounding (GO:0009611) | 3/167 | 0.6829931 | 1 | 0 | 0 | 0.8574736 | 0.3269295 | ADORA3;PLAT;PAX6 |
| 1055 | calcium ion homeostasis (GO:0055074) | 5/274 | 0.6830977 | 1 | 0 | 0 | 0.8710346 | 0.3319664 | JPH2;C1QTNF1;EDN2;STC1;TNNI3 |
| 1056 | regulation of cell shape (GO:0008360) | 2/112 | 0.6837452 | 1 | 0 | 0 | 0.8523696 | 0.3240453 | CCL24;CDC42EP5 |
| 1057 | regulation of transmembrane transport (GO:0034762) | 6/327 | 0.6844458 | 1 | 0 | 0 | 0.8758293 | 0.3320670 | JPH2;STC1;KCNN2;CACNA1E;THBS1;ADRA2A |
| 1058 | response to acid chemical (GO:0001101) | 5/275 | 0.6861652 | 1 | 0 | 0 | 0.8678672 | 0.3268708 | MUC1;BRINP1;APOB;PTGS2;CYP17A1 |
| 1059 | negative regulation of endopeptidase activity (GO:0010951) | 4/222 | 0.6867877 | 1 | 0 | 0 | 0.8600486 | 0.3231461 | SERPINB4;AHSG;HMSD;THBS1 |
| 1060 | protein maturation (GO:0051604) | 4/222 | 0.6867877 | 1 | 0 | 0 | 0.8600486 | 0.3231461 | CPE;PLAT;PTHLH;NKX3-1 |
| 1061 | positive regulation of apoptotic signaling pathway (GO:2001235) | 3/168 | 0.6868797 | 1 | 0 | 0 | 0.8523696 | 0.3201467 | IL19;THBS1;NKX3-1 |
| 1062 | peptidyl-proline modification (GO:0018208) | 1/55 | 0.6884140 | 1 | 0 | 0 | 0.8678672 | 0.3240311 | FKBP5 |
| 1063 | positive regulation of histone modification (GO:0031058) | 1/55 | 0.6884140 | 1 | 0 | 0 | 0.8678672 | 0.3240311 | MUC1 |
| 1064 | embryonic digit morphogenesis (GO:0042733) | 1/55 | 0.6884140 | 1 | 0 | 0 | 0.8678672 | 0.3240311 | ZBTB16 |
| 1065 | mesenchyme development (GO:0060485) | 1/55 | 0.6884140 | 1 | 0 | 0 | 0.8678672 | 0.3240311 | THBS1 |
| 1066 | JNK cascade (GO:0007254) | 1/55 | 0.6884140 | 1 | 0 | 0 | 0.8678672 | 0.3240311 | CDC42EP5 |
| 1067 | DNA duplex unwinding (GO:0032508) | 1/55 | 0.6884140 | 1 | 0 | 0 | 0.8678672 | 0.3240311 | RTEL1-TNFRSF6B |
| 1068 | single-organism carbohydrate catabolic process (GO:0044724) | 2/113 | 0.6884430 | 1 | 0 | 0 | 0.8448265 | 0.3153930 | FUT6;HKDC1 |
| 1069 | carboxylic acid transport (GO:0046942) | 4/224 | 0.6935057 | 1 | 0 | 0 | 0.8523696 | 0.3119638 | NTRK2;SLCO1B3;SLC6A1;SLC13A5 |
| 1070 | negative regulation of cell motility (GO:2000146) | 3/170 | 0.6945459 | 1 | 0 | 0 | 0.8423417 | 0.3070311 | STC1;ALOX15B;THBS1 |
| 1071 | protein autophosphorylation (GO:0046777) | 3/170 | 0.6945459 | 1 | 0 | 0 | 0.8423417 | 0.3070311 | NTRK2;NEK6;IRAK3 |
| 1072 | regulation of dendrite morphogenesis (GO:0048814) | 1/56 | 0.6949597 | 1 | 0 | 0 | 0.8523696 | 0.3101785 | CUX2 |
| 1073 | positive regulation of chromatin modification (GO:1903310) | 1/56 | 0.6949597 | 1 | 0 | 0 | 0.8523696 | 0.3101785 | MUC1 |
| 1074 | iron ion transport (GO:0006826) | 1/56 | 0.6949597 | 1 | 0 | 0 | 0.8523696 | 0.3101785 | REP15 |
| 1075 | regulation of chemokine production (GO:0032642) | 1/56 | 0.6949597 | 1 | 0 | 0 | 0.8523696 | 0.3101785 | ALOX15B |
| 1076 | muscle tissue morphogenesis (GO:0060415) | 1/56 | 0.6949597 | 1 | 0 | 0 | 0.8523696 | 0.3101785 | TNNI3 |
| 1077 | negative regulation of protein complex disassembly (GO:0043242) | 1/56 | 0.6949597 | 1 | 0 | 0 | 0.8523696 | 0.3101785 | IRAK3 |
| 1078 | organic acid transport (GO:0015849) | 4/226 | 0.7001206 | 1 | 0 | 0 | 0.8448265 | 0.3011829 | NTRK2;SLCO1B3;SLC6A1;SLC13A5 |
| 1079 | DNA geometric change (GO:0032392) | 1/57 | 0.7013682 | 1 | 0 | 0 | 0.8374157 | 0.2970500 | RTEL1-TNFRSF6B |
| 1080 | positive regulation of response to DNA damage stimulus (GO:2001022) | 1/57 | 0.7013682 | 1 | 0 | 0 | 0.8374157 | 0.2970500 | NKX3-1 |
| 1081 | positive regulation of extrinsic apoptotic signaling pathway (GO:2001238) | 1/57 | 0.7013682 | 1 | 0 | 0 | 0.8374157 | 0.2970500 | THBS1 |
| 1082 | homotypic cell-cell adhesion (GO:0034109) | 1/57 | 0.7013682 | 1 | 0 | 0 | 0.8374157 | 0.2970500 | CEACAM5 |
| 1083 | actomyosin structure organization (GO:0031032) | 1/57 | 0.7013682 | 1 | 0 | 0 | 0.8374157 | 0.2970500 | MYLK3 |
| 1084 | cell-cell recognition (GO:0009988) | 1/57 | 0.7013682 | 1 | 0 | 0 | 0.8374157 | 0.2970500 | CATSPERB |
| 1085 | regulation of myotube differentiation (GO:0010830) | 1/57 | 0.7013682 | 1 | 0 | 0 | 0.8374157 | 0.2970500 | CEACAM5 |
| 1086 | response to monosaccharide (GO:0034284) | 2/116 | 0.7021932 | 1 | 0 | 0 | 0.8229775 | 0.2909610 | PTGS2;THBS1 |
| 1087 | cellular response to molecule of bacterial origin (GO:0071219) | 2/116 | 0.7021932 | 1 | 0 | 0 | 0.8229775 | 0.2909610 | CSF3;CYP17A1 |
| 1088 | embryonic pattern specification (GO:0009880) | 1/58 | 0.7076424 | 1 | 0 | 0 | 0.8229775 | 0.2845991 | ZBTB16 |
| 1089 | regulation of postsynaptic membrane potential (GO:0060078) | 1/58 | 0.7076424 | 1 | 0 | 0 | 0.8229775 | 0.2845991 | CUX2 |
| 1090 | neuron-neuron synaptic transmission (GO:0007270) | 1/58 | 0.7076424 | 1 | 0 | 0 | 0.8229775 | 0.2845991 | PLAT |
| 1091 | cyclic nucleotide metabolic process (GO:0009187) | 1/58 | 0.7076424 | 1 | 0 | 0 | 0.8229775 | 0.2845991 | PTHLH |
| 1092 | retina development in camera-type eye (GO:0060041) | 1/58 | 0.7076424 | 1 | 0 | 0 | 0.8229775 | 0.2845991 | PAX6 |
| 1093 | regulation of hormone levels (GO:0010817) | 4/229 | 0.7098499 | 1 | 0 | 0 | 0.8337589 | 0.2857306 | TPO;ADORA3;CPE;CYP17A1 |
| 1094 | positive regulation of neurogenesis (GO:0050769) | 5/283 | 0.7099804 | 1 | 0 | 0 | 0.8433339 | 0.2888570 | NTRK2;CUX2;BRINP1;PAX6;FEZF1 |
| 1095 | anion transport (GO:0006820) | 8/443 | 0.7134001 | 1 | 0 | 0 | 0.8619900 | 0.2911051 | NTRK2;ANO1;SLC26A2;SLCO1B3;ATP10B;ANO7;SLC6A1;SLC13A5 |
| 1096 | cellular ketone metabolic process (GO:0042180) | 1/59 | 0.7137851 | 1 | 0 | 0 | 0.8090288 | 0.2727830 | CYP17A1 |
| 1097 | steroid hormone mediated signaling pathway (GO:0043401) | 1/59 | 0.7137851 | 1 | 0 | 0 | 0.8090288 | 0.2727830 | NKX3-1 |
| 1098 | positive regulation of cytokine biosynthetic process (GO:0042108) | 1/59 | 0.7137851 | 1 | 0 | 0 | 0.8090288 | 0.2727830 | THBS1 |
| 1099 | tetrapyrrole metabolic process (GO:0033013) | 1/59 | 0.7137851 | 1 | 0 | 0 | 0.8090288 | 0.2727830 | TCN1 |
| 1100 | sterol metabolic process (GO:0016125) | 2/119 | 0.7154359 | 1 | 0 | 0 | 0.8022302 | 0.2686374 | APOB;CYP17A1 |
| 1101 | cytosolic calcium ion homeostasis (GO:0051480) | 3/176 | 0.7166933 | 1 | 0 | 0 | 0.8136255 | 0.2710246 | JPH2;C1QTNF1;EDN2 |
| 1102 | regulation of anatomical structure size (GO:0090066) | 4/232 | 0.7193477 | 1 | 0 | 0 | 0.8229775 | 0.2710974 | CCL24;CSF3;EDN2;CDC42EP5 |
| 1103 | positive regulation of organelle organization (GO:0010638) | 6/340 | 0.7197285 | 1 | 0 | 0 | 0.8423417 | 0.2770304 | CCL24;CSF3;MUC1;CDC42EP5;DOC2B;MYLK3 |
| 1104 | regulation of leukocyte mediated immunity (GO:0002703) | 2/120 | 0.7197391 | 1 | 0 | 0 | 0.7955449 | 0.2616281 | AZGP1;ADORA3 |
| 1105 | epidermis development (GO:0008544) | 2/120 | 0.7197391 | 1 | 0 | 0 | 0.7955449 | 0.2616281 | CDSN;PTHLH |
| 1106 | regulation of chemotaxis (GO:0050920) | 2/120 | 0.7197391 | 1 | 0 | 0 | 0.7955449 | 0.2616281 | EDN2;THBS1 |
| 1107 | carbohydrate catabolic process (GO:0016052) | 2/120 | 0.7197391 | 1 | 0 | 0 | 0.7955449 | 0.2616281 | FUT6;HKDC1 |
| 1108 | single fertilization (GO:0007338) | 1/60 | 0.7197990 | 1 | 0 | 0 | 0.7955449 | 0.2615619 | CATSPERB |
| 1109 | neuron development (GO:0048666) | 2/121 | 0.7239875 | 1 | 0 | 0 | 0.7889702 | 0.2548225 | NTRK2;PAX6 |
| 1110 | actin filament-based movement (GO:0030048) | 1/61 | 0.7256868 | 1 | 0 | 0 | 0.7825032 | 0.2508993 | TNNI3 |
| 1111 | cell fate specification (GO:0001708) | 1/61 | 0.7256868 | 1 | 0 | 0 | 0.7825032 | 0.2508993 | PAX6 |
| 1112 | secretion by tissue (GO:0032941) | 1/61 | 0.7256868 | 1 | 0 | 0 | 0.7825032 | 0.2508993 | CHRM1 |
| 1113 | kidney development (GO:0001822) | 2/122 | 0.7281814 | 1 | 0 | 0 | 0.7825032 | 0.2482140 | ZBTB16;NKX3-1 |
| 1114 | response to oxidative stress (GO:0006979) | 5/290 | 0.7297575 | 1 | 0 | 0 | 0.8229775 | 0.2592733 | TPO;PXDN;PYCR1;PTGS2;WNT16 |
| 1115 | cell aging (GO:0007569) | 1/62 | 0.7314513 | 1 | 0 | 0 | 0.7698822 | 0.2407612 | WNT16 |
| 1116 | negative regulation of G-protein coupled receptor protein signaling pathway (GO:0045744) | 1/62 | 0.7314513 | 1 | 0 | 0 | 0.7698822 | 0.2407612 | ADRA2A |
| 1117 | stem cell differentiation (GO:0048863) | 1/62 | 0.7314513 | 1 | 0 | 0 | 0.7698822 | 0.2407612 | SIX3 |
| 1118 | regulation of cation channel activity (GO:2001257) | 1/62 | 0.7314513 | 1 | 0 | 0 | 0.7698822 | 0.2407612 | JPH2 |
| 1119 | positive regulation of cell morphogenesis involved in differentiation (GO:0010770) | 2/123 | 0.7323212 | 1 | 0 | 0 | 0.7761414 | 0.2417960 | NTRK2;CUX2 |
| 1120 | cellular response to steroid hormone stimulus (GO:0071383) | 2/123 | 0.7323212 | 1 | 0 | 0 | 0.7761414 | 0.2417960 | STC1;NKX3-1 |
| 1121 | divalent inorganic cation homeostasis (GO:0072507) | 5/291 | 0.7325019 | 1 | 0 | 0 | 0.8201494 | 0.2553038 | JPH2;C1QTNF1;EDN2;STC1;TNNI3 |
| 1122 | regulation of response to DNA damage stimulus (GO:2001020) | 2/124 | 0.7364074 | 1 | 0 | 0 | 0.7698822 | 0.2355622 | MUC1;NKX3-1 |
| 1123 | positive regulation of endothelial cell proliferation (GO:0001938) | 1/63 | 0.7370948 | 1 | 0 | 0 | 0.7576619 | 0.2311162 | CCL24 |
| 1124 | positive regulation of T cell differentiation (GO:0045582) | 1/63 | 0.7370948 | 1 | 0 | 0 | 0.7576619 | 0.2311162 | ZBTB16 |
| 1125 | regulation of alpha-beta T cell activation (GO:0046634) | 1/63 | 0.7370948 | 1 | 0 | 0 | 0.7576619 | 0.2311162 | ZBTB16 |
| 1126 | regulation of blood vessel size (GO:0050880) | 1/63 | 0.7370948 | 1 | 0 | 0 | 0.7576619 | 0.2311162 | EDN2 |
| 1127 | regulation of neurotransmitter transport (GO:0051588) | 1/63 | 0.7370948 | 1 | 0 | 0 | 0.7576619 | 0.2311162 | NTRK2 |
| 1128 | divalent inorganic cation transport (GO:0072511) | 4/238 | 0.7376519 | 1 | 0 | 0 | 0.8022302 | 0.2441052 | JPH2;TCN1;BHLHA15;CACNA1E |
| 1129 | negative regulation of cellular component movement (GO:0051271) | 3/183 | 0.7409391 | 1 | 0 | 0 | 0.7825032 | 0.2346233 | STC1;ALOX15B;THBS1 |
| 1130 | negative regulation of angiogenesis (GO:0016525) | 1/64 | 0.7426200 | 1 | 0 | 0 | 0.7458234 | 0.2219352 | THBS1 |
| 1131 | regulation of tube size (GO:0035150) | 1/64 | 0.7426200 | 1 | 0 | 0 | 0.7458234 | 0.2219352 | EDN2 |
| 1132 | regulation of synapse organization (GO:0050807) | 1/64 | 0.7426200 | 1 | 0 | 0 | 0.7458234 | 0.2219352 | CUX2 |
| 1133 | positive regulation of stem cell proliferation (GO:2000648) | 1/64 | 0.7426200 | 1 | 0 | 0 | 0.7458234 | 0.2219352 | PAX6 |
| 1134 | regulation of actin cytoskeleton organization (GO:0032956) | 4/240 | 0.7435496 | 1 | 0 | 0 | 0.7955449 | 0.2357357 | CCL24;CSF3;CDC42EP5;MYLK3 |
| 1135 | negative regulation of sequence-specific DNA binding transcription factor activity (GO:0043433) | 2/126 | 0.7444207 | 1 | 0 | 0 | 0.7576619 | 0.2236231 | IRAK3;PTHLH |
| 1136 | negative regulation of Wnt signaling pathway (GO:0030178) | 2/126 | 0.7444207 | 1 | 0 | 0 | 0.7576619 | 0.2236231 | SIX3;CTHRC1 |
| 1137 | glutamine family amino acid metabolic process (GO:0009064) | 1/65 | 0.7480294 | 1 | 0 | 0 | 0.7343492 | 0.2131911 | PYCR1 |
| 1138 | negative regulation of ossification (GO:0030279) | 1/65 | 0.7480294 | 1 | 0 | 0 | 0.7343492 | 0.2131911 | AHSG |
| 1139 | negative regulation of NF-kappaB transcription factor activity (GO:0032088) | 1/65 | 0.7480294 | 1 | 0 | 0 | 0.7343492 | 0.2131911 | IRAK3 |
| 1140 | negative regulation of lipid metabolic process (GO:0045833) | 1/65 | 0.7480294 | 1 | 0 | 0 | 0.7343492 | 0.2131911 | ADRA2A |
| 1141 | positive regulation of peptide hormone secretion (GO:0090277) | 1/65 | 0.7480294 | 1 | 0 | 0 | 0.7343492 | 0.2131911 | DOC2B |
| 1142 | circadian rhythm (GO:0007623) | 2/127 | 0.7483486 | 1 | 0 | 0 | 0.7516960 | 0.2179064 | NTRK2;SIX3 |
| 1143 | calcium ion transmembrane transport (GO:0070588) | 2/128 | 0.7522246 | 1 | 0 | 0 | 0.7458234 | 0.2123511 | JPH2;CACNA1E |
| 1144 | amino acid transport (GO:0006865) | 2/128 | 0.7522246 | 1 | 0 | 0 | 0.7458234 | 0.2123511 | NTRK2;SLC6A1 |
| 1145 | regulation of acute inflammatory response (GO:0002673) | 1/66 | 0.7533254 | 1 | 0 | 0 | 0.7232227 | 0.2048586 | PTGS2 |
| 1146 | positive regulation of translation (GO:0045727) | 1/66 | 0.7533254 | 1 | 0 | 0 | 0.7232227 | 0.2048586 | THBS1 |
| 1147 | negative regulation of blood vessel morphogenesis (GO:2000181) | 1/66 | 0.7533254 | 1 | 0 | 0 | 0.7232227 | 0.2048586 | THBS1 |
| 1148 | response to ammonium ion (GO:0060359) | 1/66 | 0.7533254 | 1 | 0 | 0 | 0.7232227 | 0.2048586 | SLC6A1 |
| 1149 | negative regulation of apoptotic signaling pathway (GO:2001234) | 3/187 | 0.7540389 | 1 | 0 | 0 | 0.7657652 | 0.2161841 | MUC1;IL19;THBS1 |
| 1150 | negative regulation of hydrolase activity (GO:0051346) | 6/354 | 0.7545712 | 1 | 0 | 0 | 0.8090288 | 0.2278271 | SERPINB4;AHSG;HMSD;SSPO;TNNI3;THBS1 |
| 1151 | regulation of lipid metabolic process (GO:0019216) | 4/245 | 0.7578527 | 1 | 0 | 0 | 0.7793093 | 0.2160761 | APOB;PTGS2;ADRA2A;CYP17A1 |
| 1152 | positive regulation of peptide secretion (GO:0002793) | 1/67 | 0.7585103 | 1 | 0 | 0 | 0.7124283 | 0.1969144 | DOC2B |
| 1153 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:0006977) | 1/67 | 0.7585103 | 1 | 0 | 0 | 0.7124283 | 0.1969144 | MUC1 |
| 1154 | cellular response to mechanical stimulus (GO:0071260) | 1/67 | 0.7585103 | 1 | 0 | 0 | 0.7124283 | 0.1969144 | PTGS2 |
| 1155 | regulation of inflammatory response (GO:0050727) | 4/247 | 0.7633989 | 1 | 0 | 0 | 0.7729991 | 0.2086901 | CCL24;AHSG;ADORA3;PTGS2 |
| 1156 | negative regulation of catabolic process (GO:0009895) | 3/190 | 0.7635108 | 1 | 0 | 0 | 0.7536742 | 0.2033624 | IRAK3;TNNI3;ADRA2A |
| 1157 | cellular lipid catabolic process (GO:0044242) | 2/131 | 0.7635456 | 1 | 0 | 0 | 0.7287435 | 0.1966022 | LIPG;APOB |
| 1158 | cytokine production (GO:0001816) | 1/68 | 0.7635865 | 1 | 0 | 0 | 0.7019514 | 0.1893366 | PTGS2 |
| 1159 | signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431) | 1/68 | 0.7635865 | 1 | 0 | 0 | 0.7019514 | 0.1893366 | MUC1 |
| 1160 | intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400) | 1/68 | 0.7635865 | 1 | 0 | 0 | 0.7019514 | 0.1893366 | MUC1 |
| 1161 | positive regulation of cell development (GO:0010720) | 6/358 | 0.7639254 | 1 | 0 | 0 | 0.7999893 | 0.2154252 | NTRK2;CUX2;BRINP1;PAX6;FEZF1;MYLK3 |
| 1162 | cellular response to biotic stimulus (GO:0071216) | 2/132 | 0.7672185 | 1 | 0 | 0 | 0.7232227 | 0.1916422 | CSF3;CYP17A1 |
| 1163 | positive regulation of lymphocyte mediated immunity (GO:0002708) | 1/69 | 0.7685562 | 1 | 0 | 0 | 0.6917782 | 0.1821048 | AZGP1 |
| 1164 | negative regulation of cysteine-type endopeptidase activity involved in apoptotic process (GO:0043154) | 1/69 | 0.7685562 | 1 | 0 | 0 | 0.6917782 | 0.1821048 | THBS1 |
| 1165 | alpha-amino acid biosynthetic process (GO:1901607) | 1/69 | 0.7685562 | 1 | 0 | 0 | 0.6917782 | 0.1821048 | PYCR1 |
| 1166 | positive regulation of cytokine secretion (GO:0050715) | 1/69 | 0.7685562 | 1 | 0 | 0 | 0.6917782 | 0.1821048 | ALOX15B |
| 1167 | signal transduction involved in mitotic cell cycle checkpoint (GO:0072413) | 1/69 | 0.7685562 | 1 | 0 | 0 | 0.6917782 | 0.1821048 | MUC1 |
| 1168 | signal transduction involved in mitotic DNA damage checkpoint (GO:1902402) | 1/69 | 0.7685562 | 1 | 0 | 0 | 0.6917782 | 0.1821048 | MUC1 |
| 1169 | signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403) | 1/69 | 0.7685562 | 1 | 0 | 0 | 0.6917782 | 0.1821048 | MUC1 |
| 1170 | negative regulation of myeloid cell differentiation (GO:0045638) | 1/69 | 0.7685562 | 1 | 0 | 0 | 0.6917782 | 0.1821048 | ZBTB16 |
| 1171 | adherens junction organization (GO:0034332) | 1/69 | 0.7685562 | 1 | 0 | 0 | 0.6917782 | 0.1821048 | CDH15 |
| 1172 | negative regulation of transport (GO:0051051) | 6/361 | 0.7707671 | 1 | 0 | 0 | 0.7933412 | 0.2065615 | BMP8A;STC1;PTGS2;THBS1;ADRA2A;STXBP5L |
| 1173 | activation of MAPK activity (GO:0000187) | 2/133 | 0.7708418 | 1 | 0 | 0 | 0.7177849 | 0.1868194 | THBS1;ADRA2A |
| 1174 | positive regulation of immune effector process (GO:0002699) | 2/133 | 0.7708418 | 1 | 0 | 0 | 0.7177849 | 0.1868194 | AZGP1;ADORA3 |
| 1175 | regulation of vesicle-mediated transport (GO:0060627) | 5/306 | 0.7712574 | 1 | 0 | 0 | 0.7799460 | 0.2025778 | AHSG;ADORA3;DOC2B;ADRA2A;STXBP5L |
| 1176 | lipid transport (GO:0006869) | 3/193 | 0.7726851 | 1 | 0 | 0 | 0.7419590 | 0.1913392 | LIPG;ATP10B;APOB |
| 1177 | single-organism behavior (GO:0044708) | 6/362 | 0.7730146 | 1 | 0 | 0 | 0.7911497 | 0.2036873 | NTRK2;CUX2;PCDH15;SLC6A1;PTGS2;THBS1 |
| 1178 | hormone secretion (GO:0046879) | 1/70 | 0.7734217 | 1 | 0 | 0 | 0.6818957 | 0.1752000 | ADORA3 |
| 1179 | negative regulation of vasculature development (GO:1901343) | 1/70 | 0.7734217 | 1 | 0 | 0 | 0.6818957 | 0.1752000 | THBS1 |
| 1180 | response to heat (GO:0009408) | 1/70 | 0.7734217 | 1 | 0 | 0 | 0.6818957 | 0.1752000 | THBS1 |
| 1181 | cellular response to cytokine stimulus (GO:0071345) | 8/471 | 0.7736317 | 1 | 0 | 0 | 0.8107464 | 0.2080856 | CSF3;EDN2;IL1R2;IRAK3;APOB;THBS1;MYLK3;NKX3-1 |
| 1182 | cell fate commitment (GO:0045165) | 2/134 | 0.7744158 | 1 | 0 | 0 | 0.7124283 | 0.1821297 | PAX6;WNT16 |
| 1183 | pyruvate metabolic process (GO:0006090) | 1/71 | 0.7781852 | 1 | 0 | 0 | 0.6722915 | 0.1686045 | HKDC1 |
| 1184 | tissue remodeling (GO:0048771) | 1/71 | 0.7781852 | 1 | 0 | 0 | 0.6722915 | 0.1686045 | WNT16 |
| 1185 | signal transduction involved in DNA damage checkpoint (GO:0072422) | 1/71 | 0.7781852 | 1 | 0 | 0 | 0.6722915 | 0.1686045 | MUC1 |
| 1186 | striated muscle contraction (GO:0006941) | 1/71 | 0.7781852 | 1 | 0 | 0 | 0.6722915 | 0.1686045 | TNNI3 |
| 1187 | negative regulation of cysteine-type endopeptidase activity (GO:2000117) | 1/71 | 0.7781852 | 1 | 0 | 0 | 0.6722915 | 0.1686045 | THBS1 |
| 1188 | signal transduction involved in DNA integrity checkpoint (GO:0072401) | 1/71 | 0.7781852 | 1 | 0 | 0 | 0.6722915 | 0.1686045 | MUC1 |
| 1189 | regulation of epidermal growth factor receptor signaling pathway (GO:0042058) | 1/71 | 0.7781852 | 1 | 0 | 0 | 0.6722915 | 0.1686045 | ADRA2A |
| 1190 | receptor metabolic process (GO:0043112) | 1/71 | 0.7781852 | 1 | 0 | 0 | 0.6722915 | 0.1686045 | REP15 |
| 1191 | organophosphate ester transport (GO:0015748) | 1/71 | 0.7781852 | 1 | 0 | 0 | 0.6722915 | 0.1686045 | ATP10B |
| 1192 | positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains (GO:0002824) | 1/71 | 0.7781852 | 1 | 0 | 0 | 0.6722915 | 0.1686045 | AZGP1 |
| 1193 | renal system process (GO:0003014) | 1/71 | 0.7781852 | 1 | 0 | 0 | 0.6722915 | 0.1686045 | HSD11B2 |
| 1194 | body fluid secretion (GO:0007589) | 1/71 | 0.7781852 | 1 | 0 | 0 | 0.6722915 | 0.1686045 | CHRM1 |
| 1195 | biomineral tissue development (GO:0031214) | 1/71 | 0.7781852 | 1 | 0 | 0 | 0.6722915 | 0.1686045 | PTGS2 |
| 1196 | positive regulation of cell projection organization (GO:0031346) | 3/195 | 0.7786383 | 1 | 0 | 0 | 0.7343492 | 0.1837405 | NTRK2;CUX2;CDC42EP5 |
| 1197 | smoothened signaling pathway (GO:0007224) | 1/72 | 0.7828487 | 1 | 0 | 0 | 0.6629541 | 0.1623016 | PAX6 |
| 1198 | regulation of fatty acid metabolic process (GO:0019217) | 1/72 | 0.7828487 | 1 | 0 | 0 | 0.6629541 | 0.1623016 | PTGS2 |
| 1199 | regulation of heart rate (GO:0002027) | 1/72 | 0.7828487 | 1 | 0 | 0 | 0.6629541 | 0.1623016 | EDN2 |
| 1200 | positive regulation of chromosome organization (GO:2001252) | 1/72 | 0.7828487 | 1 | 0 | 0 | 0.6629541 | 0.1623016 | MUC1 |
| 1201 | signal transduction involved in cell cycle checkpoint (GO:0072395) | 1/72 | 0.7828487 | 1 | 0 | 0 | 0.6629541 | 0.1623016 | MUC1 |
| 1202 | response to metal ion (GO:0010038) | 4/255 | 0.7846000 | 1 | 0 | 0 | 0.7487482 | 0.1816322 | TFF1;SLC6A1;PTGS2;THBS1 |
| 1203 | regulation of ion transmembrane transporter activity (GO:0032412) | 2/137 | 0.7848476 | 1 | 0 | 0 | 0.6968277 | 0.1688175 | JPH2;ADRA2A |
| 1204 | positive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway (GO:0090100) | 1/73 | 0.7874144 | 1 | 0 | 0 | 0.6538726 | 0.1562759 | THBS1 |
| 1205 | negative regulation of transforming growth factor beta receptor signaling pathway (GO:0030512) | 1/73 | 0.7874144 | 1 | 0 | 0 | 0.6538726 | 0.1562759 | FBN2 |
| 1206 | intracellular steroid hormone receptor signaling pathway (GO:0030518) | 1/73 | 0.7874144 | 1 | 0 | 0 | 0.6538726 | 0.1562759 | NKX3-1 |
| 1207 | positive regulation of nervous system development (GO:0051962) | 5/313 | 0.7878191 | 1 | 0 | 0 | 0.7625031 | 0.1818469 | NTRK2;CUX2;BRINP1;PAX6;FEZF1 |
| 1208 | negative regulation of response to wounding (GO:1903035) | 2/138 | 0.7882296 | 1 | 0 | 0 | 0.6917782 | 0.1646196 | C1QTNF1;PLAT |
| 1209 | positive regulation of peptidyl-tyrosine phosphorylation (GO:0050731) | 2/139 | 0.7915648 | 1 | 0 | 0 | 0.6868014 | 0.1605354 | CSF3;ADRA2A |
| 1210 | positive regulation of adaptive immune response (GO:0002821) | 1/74 | 0.7918844 | 1 | 0 | 0 | 0.6450364 | 0.1505127 | AZGP1 |
| 1211 | negative regulation of MAP kinase activity (GO:0043407) | 1/74 | 0.7918844 | 1 | 0 | 0 | 0.6450364 | 0.1505127 | IRAK3 |
| 1212 | cellular response to starvation (GO:0009267) | 1/74 | 0.7918844 | 1 | 0 | 0 | 0.6450364 | 0.1505127 | FOXA3 |
| 1213 | regulation of ERBB signaling pathway (GO:1901184) | 1/74 | 0.7918844 | 1 | 0 | 0 | 0.6450364 | 0.1505127 | ADRA2A |
| 1214 | spindle organization (GO:0007051) | 1/74 | 0.7918844 | 1 | 0 | 0 | 0.6450364 | 0.1505127 | NEK6 |
| 1215 | regulation of epithelial cell proliferation (GO:0050678) | 4/258 | 0.7921515 | 1 | 0 | 0 | 0.7400418 | 0.1724317 | CCL24;PAX6;THBS1;NKX3-1 |
| 1216 | regulation of peptidase activity (GO:0052547) | 6/372 | 0.7945911 | 1 | 0 | 0 | 0.7698822 | 0.1770172 | SERPINB4;AHSG;HMSD;SSPO;THBS1;NKX3-1 |
| 1217 | cell-substrate adhesion (GO:0031589) | 2/140 | 0.7948536 | 1 | 0 | 0 | 0.6818957 | 0.1565614 | ITGA10;NID2 |
| 1218 | glycoprotein metabolic process (GO:0009100) | 1/75 | 0.7962606 | 1 | 0 | 0 | 0.6364360 | 0.1449984 | B3GNT6 |
| 1219 | hormone transport (GO:0009914) | 1/75 | 0.7962606 | 1 | 0 | 0 | 0.6364360 | 0.1449984 | ADORA3 |
| 1220 | negative regulation of intrinsic apoptotic signaling pathway (GO:2001243) | 1/75 | 0.7962606 | 1 | 0 | 0 | 0.6364360 | 0.1449984 | MUC1 |
| 1221 | wound healing (GO:0042060) | 1/75 | 0.7962606 | 1 | 0 | 0 | 0.6364360 | 0.1449984 | PLAT |
| 1222 | positive regulation of lymphocyte differentiation (GO:0045621) | 1/75 | 0.7962606 | 1 | 0 | 0 | 0.6364360 | 0.1449984 | ZBTB16 |
| 1223 | regulation of transmembrane transporter activity (GO:0022898) | 2/141 | 0.7980965 | 1 | 0 | 0 | 0.6770595 | 0.1526943 | JPH2;ADRA2A |
| 1224 | response to reactive oxygen species (GO:0000302) | 2/141 | 0.7980965 | 1 | 0 | 0 | 0.6770595 | 0.1526943 | TPO;PXDN |
| 1225 | negative regulation of cell cycle (GO:0045786) | 7/430 | 0.7998336 | 1 | 0 | 0 | 0.7770439 | 0.1735540 | CGREF1;MUC1;BRINP1;PTGS2;ALOX15B;THBS1;NKX3-1 |
| 1226 | homophilic cell adhesion via plasma membrane adhesion molecules (GO:0007156) | 2/142 | 0.8012940 | 1 | 0 | 0 | 0.6722915 | 0.1489309 | PCDH15;CDH15 |
| 1227 | response to toxic substance (GO:0009636) | 2/142 | 0.8012940 | 1 | 0 | 0 | 0.6722915 | 0.1489309 | SLC6A1;CYP17A1 |
| 1228 | negative regulation of locomotion (GO:0040013) | 3/204 | 0.8038593 | 1 | 0 | 0 | 0.7019514 | 0.1532577 | STC1;ALOX15B;THBS1 |
| 1229 | regulation of protein import into nucleus (GO:0042306) | 2/143 | 0.8044466 | 1 | 0 | 0 | 0.6675902 | 0.1452681 | CSF3;PTGS2 |
| 1230 | DNA damage checkpoint (GO:0000077) | 1/77 | 0.8047394 | 1 | 0 | 0 | 0.6199052 | 0.1346662 | NEK6 |
| 1231 | regulation of smooth muscle cell proliferation (GO:0048660) | 1/77 | 0.8047394 | 1 | 0 | 0 | 0.6199052 | 0.1346662 | PTGS2 |
| 1232 | regulation of oxidoreductase activity (GO:0051341) | 1/77 | 0.8047394 | 1 | 0 | 0 | 0.6199052 | 0.1346662 | EDN2 |
| 1233 | positive regulation of neuron projection development (GO:0010976) | 2/144 | 0.8075547 | 1 | 0 | 0 | 0.6629541 | 0.1417028 | NTRK2;CUX2 |
| 1234 | positive regulation of peptidyl-serine phosphorylation (GO:0033138) | 1/78 | 0.8088459 | 1 | 0 | 0 | 0.6119577 | 0.1298249 | CSF3 |
| 1235 | regulation of cell-matrix adhesion (GO:0001952) | 1/78 | 0.8088459 | 1 | 0 | 0 | 0.6119577 | 0.1298249 | THBS1 |
| 1236 | regulation of membrane potential (GO:0042391) | 4/266 | 0.8112544 | 1 | 0 | 0 | 0.7177849 | 0.1501416 | ANO1;CUX2;PYCR1;CACNA1E |
| 1237 | regulation of production of molecular mediator of immune response (GO:0002700) | 1/79 | 0.8128663 | 1 | 0 | 0 | 0.6042114 | 0.1251858 | IRAK3 |
| 1238 | multicellular organism growth (GO:0035264) | 1/79 | 0.8128663 | 1 | 0 | 0 | 0.6042114 | 0.1251858 | PCDH15 |
| 1239 | developmental growth involved in morphogenesis (GO:0060560) | 1/79 | 0.8128663 | 1 | 0 | 0 | 0.6042114 | 0.1251858 | PTHLH |
| 1240 | cytokinesis (GO:0000910) | 1/79 | 0.8128663 | 1 | 0 | 0 | 0.6042114 | 0.1251858 | NEK6 |
| 1241 | neuromuscular process (GO:0050905) | 1/79 | 0.8128663 | 1 | 0 | 0 | 0.6042114 | 0.1251858 | PCDH15 |
| 1242 | behavior (GO:0007610) | 8/494 | 0.8158309 | 1 | 0 | 0 | 0.7729991 | 0.1573426 | NTRK2;CUX2;ADM2;SIX3;PCDH15;SLC6A1;PTGS2;THBS1 |
| 1243 | negative regulation of neuron differentiation (GO:0045665) | 2/147 | 0.8166169 | 1 | 0 | 0 | 0.6494244 | 0.1315638 | SIX3;PAX6 |
| 1244 | cell morphogenesis involved in differentiation (GO:0000904) | 2/147 | 0.8166169 | 1 | 0 | 0 | 0.6494244 | 0.1315638 | STC1;WNT16 |
| 1245 | regulation of organelle assembly (GO:1902115) | 1/80 | 0.8168022 | 1 | 0 | 0 | 0.5966587 | 0.1207388 | MYLK3 |
| 1246 | regulation of protein complex disassembly (GO:0043244) | 1/80 | 0.8168022 | 1 | 0 | 0 | 0.5966587 | 0.1207388 | IRAK3 |
| 1247 | Ras protein signal transduction (GO:0007265) | 2/148 | 0.8195518 | 1 | 0 | 0 | 0.6450364 | 0.1283607 | CDC42EP5;ADRA2A |
| 1248 | organic anion transport (GO:0015711) | 5/328 | 0.8201587 | 1 | 0 | 0 | 0.7276326 | 0.1442585 | NTRK2;SLCO1B3;ATP10B;SLC6A1;SLC13A5 |
| 1249 | retinoid metabolic process (GO:0001523) | 1/81 | 0.8206556 | 1 | 0 | 0 | 0.5892926 | 0.1164747 | APOB |
| 1250 | negative regulation of immune effector process (GO:0002698) | 1/81 | 0.8206556 | 1 | 0 | 0 | 0.5892926 | 0.1164747 | IRAK3 |
| 1251 | protein heterooligomerization (GO:0051291) | 1/81 | 0.8206556 | 1 | 0 | 0 | 0.5892926 | 0.1164747 | C1QTNF1 |
| 1252 | regulation of reactive oxygen species metabolic process (GO:2000377) | 1/81 | 0.8206556 | 1 | 0 | 0 | 0.5892926 | 0.1164747 | THBS1 |
| 1253 | regulation of cellular amine metabolic process (GO:0033238) | 1/82 | 0.8244281 | 1 | 0 | 0 | 0.5821061 | 0.1123845 | GPR37 |
| 1254 | male gonad development (GO:0008584) | 1/82 | 0.8244281 | 1 | 0 | 0 | 0.5821061 | 0.1123845 | NKX3-1 |
| 1255 | MyD88-dependent toll-like receptor signaling pathway (GO:0002755) | 1/82 | 0.8244281 | 1 | 0 | 0 | 0.5821061 | 0.1123845 | IRAK3 |
| 1256 | organic acid biosynthetic process (GO:0016053) | 4/272 | 0.8246228 | 1 | 0 | 0 | 0.7019514 | 0.1353567 | EDN2;PYCR1;PTGS2;ALOX15B |
| 1257 | carboxylic acid biosynthetic process (GO:0046394) | 4/272 | 0.8246228 | 1 | 0 | 0 | 0.7019514 | 0.1353567 | EDN2;PYCR1;PTGS2;ALOX15B |
| 1258 | positive regulation of defense response (GO:0031349) | 4/272 | 0.8246228 | 1 | 0 | 0 | 0.7019514 | 0.1353567 | CCL24;ADORA3;IRAK3;PTGS2 |
| 1259 | actin filament organization (GO:0007015) | 2/150 | 0.8252959 | 1 | 0 | 0 | 0.6364360 | 0.1222042 | PCDH15;SHROOM1 |
| 1260 | regulation of organ morphogenesis (GO:2000027) | 2/150 | 0.8252959 | 1 | 0 | 0 | 0.6364360 | 0.1222042 | CHAD;CTHRC1 |
| 1261 | activation of cysteine-type endopeptidase activity involved in apoptotic process (GO:0006919) | 1/83 | 0.8281214 | 1 | 0 | 0 | 0.5750927 | 0.1084599 | NKX3-1 |
| 1262 | myeloid leukocyte differentiation (GO:0002573) | 1/83 | 0.8281214 | 1 | 0 | 0 | 0.5750927 | 0.1084599 | CSF3 |
| 1263 | calcium ion transport (GO:0006816) | 3/215 | 0.8313669 | 1 | 0 | 0 | 0.6660376 | 0.1230065 | JPH2;BHLHA15;CACNA1E |
| 1264 | integrin-mediated signaling pathway (GO:0007229) | 1/84 | 0.8317373 | 1 | 0 | 0 | 0.5682464 | 0.1046930 | ITGA10 |
| 1265 | peptidyl-serine phosphorylation (GO:0018105) | 1/84 | 0.8317373 | 1 | 0 | 0 | 0.5682464 | 0.1046930 | NEK6 |
| 1266 | regulation of interleukin-6 production (GO:0032675) | 1/84 | 0.8317373 | 1 | 0 | 0 | 0.5682464 | 0.1046930 | IRAK3 |
| 1267 | post-embryonic development (GO:0009791) | 1/84 | 0.8317373 | 1 | 0 | 0 | 0.5682464 | 0.1046930 | APOB |
| 1268 | regulation of transporter activity (GO:0032409) | 2/153 | 0.8336044 | 1 | 0 | 0 | 0.6239568 | 0.1135578 | JPH2;ADRA2A |
| 1269 | nucleoside monophosphate biosynthetic process (GO:0009124) | 1/85 | 0.8352772 | 1 | 0 | 0 | 0.5615611 | 0.1010763 | ENTPD8 |
| 1270 | positive regulation of cell cycle arrest (GO:0071158) | 1/85 | 0.8352772 | 1 | 0 | 0 | 0.5615611 | 0.1010763 | MUC1 |
| 1271 | cellular response to light stimulus (GO:0071482) | 1/85 | 0.8352772 | 1 | 0 | 0 | 0.5615611 | 0.1010763 | PTGS2 |
| 1272 | myeloid cell differentiation (GO:0030099) | 2/154 | 0.8362938 | 1 | 0 | 0 | 0.6199052 | 0.1108237 | CSF3;ZBTB16 |
| 1273 | positive regulation of MAPK cascade (GO:0043410) | 6/395 | 0.8382122 | 1 | 0 | 0 | 0.7250536 | 0.1279603 | NTRK2;C1QTNF1;GPR37;WNT16;THBS1;ADRA2A |
| 1274 | regulation of binding (GO:0051098) | 3/218 | 0.8382708 | 1 | 0 | 0 | 0.6568720 | 0.1158815 | CSF3;NKX3-1;CTHRC1 |
| 1275 | cellular chemical homeostasis (GO:0055082) | 7/452 | 0.8385671 | 1 | 0 | 0 | 0.7392232 | 0.1301482 | JPH2;C1QTNF1;EDN2;HKDC1;STC1;TNNI3;FOXA3 |
| 1276 | cell-type specific apoptotic process (GO:0097285) | 1/86 | 0.8387428 | 1 | 0 | 0 | 0.5550314 | 0.0976029 | SIX3 |
| 1277 | myeloid leukocyte activation (GO:0002274) | 1/86 | 0.8387428 | 1 | 0 | 0 | 0.5550314 | 0.0976029 | EDN2 |
| 1278 | DNA integrity checkpoint (GO:0031570) | 1/86 | 0.8387428 | 1 | 0 | 0 | 0.5550314 | 0.0976029 | NEK6 |
| 1279 | negative regulation of homeostatic process (GO:0032845) | 1/86 | 0.8387428 | 1 | 0 | 0 | 0.5550314 | 0.0976029 | ADRA2A |
| 1280 | negative regulation of neuron death (GO:1901215) | 2/155 | 0.8389439 | 1 | 0 | 0 | 0.6159058 | 0.1081601 | NTRK2;CSF3 |
| 1281 | multicellular organismal development (GO:0007275) | 7/453 | 0.8401763 | 1 | 0 | 0 | 0.7375913 | 0.1284468 | CSF3;CATSPERB;PAX6;WNT16;C8ORF22;SPDEF;NKX3-1 |
| 1282 | negative regulation of mitotic cell cycle (GO:0045930) | 3/219 | 0.8405173 | 1 | 0 | 0 | 0.6538726 | 0.1136023 | MUC1;BRINP1;NKX3-1 |
| 1283 | regulation of intracellular protein transport (GO:0033157) | 3/219 | 0.8405173 | 1 | 0 | 0 | 0.6538726 | 0.1136023 | CSF3;CHRM1;PTGS2 |
| 1284 | regulation of protein localization to nucleus (GO:1900180) | 2/156 | 0.8415551 | 1 | 0 | 0 | 0.6119577 | 0.1055650 | CSF3;PTGS2 |
| 1285 | triglyceride metabolic process (GO:0006641) | 1/87 | 0.8421357 | 1 | 0 | 0 | 0.5486517 | 0.0942661 | APOB |
| 1286 | regulation of receptor activity (GO:0010469) | 1/87 | 0.8421357 | 1 | 0 | 0 | 0.5486517 | 0.0942661 | ADRA2A |
| 1287 | diterpenoid metabolic process (GO:0016101) | 1/87 | 0.8421357 | 1 | 0 | 0 | 0.5486517 | 0.0942661 | APOB |
| 1288 | activation of cysteine-type endopeptidase activity (GO:0097202) | 1/88 | 0.8454574 | 1 | 0 | 0 | 0.5424170 | 0.0910596 | NKX3-1 |
| 1289 | adult locomotory behavior (GO:0008344) | 1/88 | 0.8454574 | 1 | 0 | 0 | 0.5424170 | 0.0910596 | PCDH15 |
| 1290 | sensory perception (GO:0007600) | 7/457 | 0.8464860 | 1 | 0 | 0 | 0.7311354 | 0.1218522 | OMP;SIX3;GRM8;PCDH15;PAX6;PTGS2;ADRA2A |
| 1291 | energy reserve metabolic process (GO:0006112) | 2/158 | 0.8466628 | 1 | 0 | 0 | 0.6042114 | 0.1005726 | CACNA1E;ADRA2A |
| 1292 | phototransduction, visible light (GO:0007603) | 1/89 | 0.8487093 | 1 | 0 | 0 | 0.5363224 | 0.0879775 | APOB |
| 1293 | chromosome segregation (GO:0007059) | 1/89 | 0.8487093 | 1 | 0 | 0 | 0.5363224 | 0.0879775 | NEK6 |
| 1294 | RNA phosphodiester bond hydrolysis (GO:0090501) | 1/89 | 0.8487093 | 1 | 0 | 0 | 0.5363224 | 0.0879775 | AZGP1 |
| 1295 | stress-activated MAPK cascade (GO:0051403) | 1/89 | 0.8487093 | 1 | 0 | 0 | 0.5363224 | 0.0879775 | CDC42EP5 |
| 1296 | cell junction assembly (GO:0034329) | 2/160 | 0.8516207 | 1 | 0 | 0 | 0.5966587 | 0.0958317 | CDH15;FLNC |
| 1297 | water-soluble vitamin metabolic process (GO:0006767) | 1/90 | 0.8518930 | 1 | 0 | 0 | 0.5303633 | 0.0850142 | TCN1 |
| 1298 | positive regulation of endocytosis (GO:0045807) | 1/90 | 0.8518930 | 1 | 0 | 0 | 0.5303633 | 0.0850142 | AHSG |
| 1299 | regulation of cellular response to stress (GO:0080135) | 6/404 | 0.8531191 | 1 | 0 | 0 | 0.7089014 | 0.1126133 | MUC1;GPR37;NEK6;PYCR1;WNT16;NKX3-1 |
| 1300 | regulation of extrinsic apoptotic signaling pathway (GO:2001236) | 2/161 | 0.8540446 | 1 | 0 | 0 | 0.5929528 | 0.0935513 | IL19;THBS1 |
| 1301 | regulation of protein secretion (GO:0050708) | 2/161 | 0.8540446 | 1 | 0 | 0 | 0.5929528 | 0.0935513 | ALOX15B;STXBP5L |
| 1302 | regulation of neuron differentiation (GO:0045664) | 6/405 | 0.8547041 | 1 | 0 | 0 | 0.7071511 | 0.1110227 | NTRK2;CUX2;BRINP1;SIX3;PAX6;FEZF1 |
| 1303 | negative regulation of canonical Wnt signaling pathway (GO:0090090) | 1/91 | 0.8550098 | 1 | 0 | 0 | 0.5245351 | 0.0821644 | CTHRC1 |
| 1304 | stress-activated protein kinase signaling cascade (GO:0031098) | 1/91 | 0.8550098 | 1 | 0 | 0 | 0.5245351 | 0.0821644 | CDC42EP5 |
| 1305 | DNA damage response, signal transduction by p53 class mediator (GO:0030330) | 1/91 | 0.8550098 | 1 | 0 | 0 | 0.5245351 | 0.0821644 | MUC1 |
| 1306 | leukocyte migration (GO:0050900) | 3/226 | 0.8555008 | 1 | 0 | 0 | 0.6336199 | 0.0988879 | CCL24;EDN2;APOB |
| 1307 | iron ion homeostasis (GO:0055072) | 1/92 | 0.8580612 | 1 | 0 | 0 | 0.5188337 | 0.0794230 | LCN2 |
| 1308 | alpha-amino acid catabolic process (GO:1901606) | 1/92 | 0.8580612 | 1 | 0 | 0 | 0.5188337 | 0.0794230 | ALDH1L2 |
| 1309 | acylglycerol metabolic process (GO:0006639) | 1/93 | 0.8610486 | 1 | 0 | 0 | 0.5132548 | 0.0767852 | APOB |
| 1310 | hormone-mediated signaling pathway (GO:0009755) | 1/93 | 0.8610486 | 1 | 0 | 0 | 0.5132548 | 0.0767852 | NKX3-1 |
| 1311 | regulation of cytokine biosynthetic process (GO:0042035) | 1/93 | 0.8610486 | 1 | 0 | 0 | 0.5132548 | 0.0767852 | THBS1 |
| 1312 | positive regulation of cell-substrate adhesion (GO:0010811) | 1/93 | 0.8610486 | 1 | 0 | 0 | 0.5132548 | 0.0767852 | THBS1 |
| 1313 | regulation of glucose metabolic process (GO:0010906) | 1/94 | 0.8639732 | 1 | 0 | 0 | 0.5077946 | 0.0742465 | C1QTNF1 |
| 1314 | regulation of cell-cell adhesion (GO:0022407) | 1/94 | 0.8639732 | 1 | 0 | 0 | 0.5077946 | 0.0742465 | C1QTNF1 |
| 1315 | neutral lipid metabolic process (GO:0006638) | 1/94 | 0.8639732 | 1 | 0 | 0 | 0.5077946 | 0.0742465 | APOB |
| 1316 | regulation of behavior (GO:0050795) | 2/166 | 0.8656311 | 1 | 0 | 0 | 0.5750927 | 0.0829838 | EDN2;THBS1 |
| 1317 | regulation of endopeptidase activity (GO:0052548) | 5/354 | 0.8667283 | 1 | 0 | 0 | 0.6741906 | 0.0964293 | SERPINB4;AHSG;HMSD;THBS1;NKX3-1 |
| 1318 | response to drug (GO:0042493) | 5/354 | 0.8667283 | 1 | 0 | 0 | 0.6741906 | 0.0964293 | HSD11B2;PTGS2;THBS1;CYP17A1;NKX3-1 |
| 1319 | regulation of lymphocyte mediated immunity (GO:0002706) | 1/95 | 0.8668363 | 1 | 0 | 0 | 0.5024494 | 0.0718026 | AZGP1 |
| 1320 | purine nucleoside biosynthetic process (GO:0042451) | 1/95 | 0.8668363 | 1 | 0 | 0 | 0.5024494 | 0.0718026 | SLC26A2 |
| 1321 | negative regulation of binding (GO:0051100) | 1/95 | 0.8668363 | 1 | 0 | 0 | 0.5024494 | 0.0718026 | NKX3-1 |
| 1322 | cellular hormone metabolic process (GO:0034754) | 1/95 | 0.8668363 | 1 | 0 | 0 | 0.5024494 | 0.0718026 | CYP17A1 |
| 1323 | purine ribonucleoside biosynthetic process (GO:0046129) | 1/95 | 0.8668363 | 1 | 0 | 0 | 0.5024494 | 0.0718026 | SLC26A2 |
| 1324 | regulation of protein targeting (GO:1903533) | 2/167 | 0.8678449 | 1 | 0 | 0 | 0.5716491 | 0.0810269 | CSF3;PTGS2 |
| 1325 | heart development (GO:0007507) | 2/167 | 0.8678449 | 1 | 0 | 0 | 0.5716491 | 0.0810269 | TNNI3;NKX3-1 |
| 1326 | fat cell differentiation (GO:0045444) | 1/96 | 0.8696394 | 1 | 0 | 0 | 0.4972156 | 0.0694494 | PTGS2 |
| 1327 | positive regulation of I-kappaB kinase/NF-kappaB signaling (GO:0043123) | 2/168 | 0.8700252 | 1 | 0 | 0 | 0.5682464 | 0.0791187 | NEK6;PTGS2 |
| 1328 | divalent metal ion transport (GO:0070838) | 3/234 | 0.8711076 | 1 | 0 | 0 | 0.6119577 | 0.0844439 | JPH2;BHLHA15;CACNA1E |
| 1329 | peptidyl-serine modification (GO:0018209) | 1/97 | 0.8723836 | 1 | 0 | 0 | 0.4920897 | 0.0671831 | NEK6 |
| 1330 | regulation of histone modification (GO:0031056) | 1/97 | 0.8723836 | 1 | 0 | 0 | 0.4920897 | 0.0671831 | MUC1 |
| 1331 | terpenoid metabolic process (GO:0006721) | 1/97 | 0.8723836 | 1 | 0 | 0 | 0.4920897 | 0.0671831 | APOB |
| 1332 | negative regulation of protein catabolic process (GO:0042177) | 1/97 | 0.8723836 | 1 | 0 | 0 | 0.4920897 | 0.0671831 | IRAK3 |
| 1333 | regulation of T cell differentiation (GO:0045580) | 1/97 | 0.8723836 | 1 | 0 | 0 | 0.4920897 | 0.0671831 | ZBTB16 |
| 1334 | angiogenesis (GO:0001525) | 3/236 | 0.8747695 | 1 | 0 | 0 | 0.6067716 | 0.0811829 | ADM2;PTGS2;THBS1 |
| 1335 | regulation of peptidyl-serine phosphorylation (GO:0033135) | 1/98 | 0.8750701 | 1 | 0 | 0 | 0.4870683 | 0.0649999 | CSF3 |
| 1336 | cellular metal ion homeostasis (GO:0006875) | 5/361 | 0.8773846 | 1 | 0 | 0 | 0.6611177 | 0.0864807 | JPH2;C1QTNF1;EDN2;STC1;TNNI3 |
| 1337 | cellular response to nutrient levels (GO:0031669) | 1/99 | 0.8777003 | 1 | 0 | 0 | 0.4821485 | 0.0628963 | FOXA3 |
| 1338 | negative regulation of G1/S transition of mitotic cell cycle (GO:2000134) | 1/99 | 0.8777003 | 1 | 0 | 0 | 0.4821485 | 0.0628963 | MUC1 |
| 1339 | negative regulation of cell cycle G1/S phase transition (GO:1902807) | 1/99 | 0.8777003 | 1 | 0 | 0 | 0.4821485 | 0.0628963 | MUC1 |
| 1340 | DNA conformation change (GO:0071103) | 1/99 | 0.8777003 | 1 | 0 | 0 | 0.4821485 | 0.0628963 | RTEL1-TNFRSF6B |
| 1341 | metal ion homeostasis (GO:0055065) | 6/422 | 0.8795660 | 1 | 0 | 0 | 0.6786639 | 0.0870906 | JPH2;C1QTNF1;EDN2;LCN2;STC1;TNNI3 |
| 1342 | actin filament-based process (GO:0030029) | 4/303 | 0.8817532 | 1 | 0 | 0 | 0.6301346 | 0.0792981 | DAAM2;TNNI3;MYLK3;ADRA2A |
| 1343 | regulation of Rho GTPase activity (GO:0032319) | 2/174 | 0.8824274 | 1 | 0 | 0 | 0.5486517 | 0.0686247 | CCL24;NTRK2 |
| 1344 | protein localization to nucleus (GO:0034504) | 1/101 | 0.8827960 | 1 | 0 | 0 | 0.4726010 | 0.0589150 | ZBTB16 |
| 1345 | detection of external stimulus (GO:0009581) | 2/175 | 0.8843850 | 1 | 0 | 0 | 0.5455165 | 0.0670237 | PCDH15;APOB |
| 1346 | hematopoietic or lymphoid organ development (GO:0048534) | 2/175 | 0.8843850 | 1 | 0 | 0 | 0.5455165 | 0.0670237 | TPO;ZBTB16 |
| 1347 | regulation of chromatin modification (GO:1903308) | 1/102 | 0.8852638 | 1 | 0 | 0 | 0.4679676 | 0.0570310 | MUC1 |
| 1348 | peptidyl-tyrosine dephosphorylation (GO:0035335) | 1/102 | 0.8852638 | 1 | 0 | 0 | 0.4679676 | 0.0570310 | PTPRH |
| 1349 | neuron projection guidance (GO:0097485) | 5/367 | 0.8859348 | 1 | 0 | 0 | 0.6503092 | 0.0787602 | UNC5A;ITGA10;SEMA3B;PAX6;FEZF1 |
| 1350 | axon guidance (GO:0007411) | 5/367 | 0.8859348 | 1 | 0 | 0 | 0.6503092 | 0.0787602 | UNC5A;ITGA10;SEMA3B;PAX6;FEZF1 |
| 1351 | regulation of cellular response to growth factor stimulus (GO:0090287) | 2/176 | 0.8863125 | 1 | 0 | 0 | 0.5424170 | 0.0654620 | FBN2;THBS1 |
| 1352 | positive regulation of mitotic cell cycle (GO:0045931) | 1/103 | 0.8876798 | 1 | 0 | 0 | 0.4634242 | 0.0552143 | NKX3-1 |
| 1353 | regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains (GO:0002822) | 1/103 | 0.8876798 | 1 | 0 | 0 | 0.4634242 | 0.0552143 | AZGP1 |
| 1354 | negative regulation of immune response (GO:0050777) | 1/103 | 0.8876798 | 1 | 0 | 0 | 0.4634242 | 0.0552143 | IRAK3 |
| 1355 | regulation of protein complex assembly (GO:0043254) | 3/244 | 0.8885121 | 1 | 0 | 0 | 0.5868774 | 0.0693730 | CCL24;CSF3;CDC42EP5 |
| 1356 | detection of visible light (GO:0009584) | 1/104 | 0.8900451 | 1 | 0 | 0 | 0.4589682 | 0.0534621 | APOB |
| 1357 | antigen processing and presentation of peptide antigen via MHC class I (GO:0002474) | 1/104 | 0.8900451 | 1 | 0 | 0 | 0.4589682 | 0.0534621 | AZGP1 |
| 1358 | detection of abiotic stimulus (GO:0009582) | 2/178 | 0.8900786 | 1 | 0 | 0 | 0.5363224 | 0.0624523 | PCDH15;APOB |
| 1359 | regulation of nucleocytoplasmic transport (GO:0046822) | 2/178 | 0.8900786 | 1 | 0 | 0 | 0.5363224 | 0.0624523 | CSF3;PTGS2 |
| 1360 | regulation of cell cycle arrest (GO:0071156) | 1/105 | 0.8923606 | 1 | 0 | 0 | 0.4545971 | 0.0517718 | MUC1 |
| 1361 | response to starvation (GO:0042594) | 1/106 | 0.8946275 | 1 | 0 | 0 | 0.4503085 | 0.0501409 | FOXA3 |
| 1362 | cellular amino acid biosynthetic process (GO:0008652) | 1/106 | 0.8946275 | 1 | 0 | 0 | 0.4503085 | 0.0501409 | PYCR1 |
| 1363 | signal transduction in response to DNA damage (GO:0042770) | 1/106 | 0.8946275 | 1 | 0 | 0 | 0.4503085 | 0.0501409 | MUC1 |
| 1364 | regulation of cytokine secretion (GO:0050707) | 1/106 | 0.8946275 | 1 | 0 | 0 | 0.4503085 | 0.0501409 | ALOX15B |
| 1365 | cell growth (GO:0016049) | 1/106 | 0.8946275 | 1 | 0 | 0 | 0.4503085 | 0.0501409 | LEFTY1 |
| 1366 | response to glucose (GO:0009749) | 1/106 | 0.8946275 | 1 | 0 | 0 | 0.4503085 | 0.0501409 | THBS1 |
| 1367 | synaptic transmission (GO:0007268) | 6/434 | 0.8948836 | 1 | 0 | 0 | 0.6598990 | 0.0732894 | CHRM1;OMP;KCNN2;PLAT;SLC6A1;CACNA1E |
| 1368 | negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway (GO:0090101) | 1/107 | 0.8968468 | 1 | 0 | 0 | 0.4461000 | 0.0485670 | FBN2 |
| 1369 | cholesterol metabolic process (GO:0008203) | 1/107 | 0.8968468 | 1 | 0 | 0 | 0.4461000 | 0.0485670 | APOB |
| 1370 | regulation of chromatin organization (GO:1902275) | 1/107 | 0.8968468 | 1 | 0 | 0 | 0.4461000 | 0.0485670 | MUC1 |
| 1371 | positive regulation of JNK cascade (GO:0046330) | 1/107 | 0.8968468 | 1 | 0 | 0 | 0.4461000 | 0.0485670 | WNT16 |
| 1372 | maintenance of protein location (GO:0045185) | 1/108 | 0.8990194 | 1 | 0 | 0 | 0.4419694 | 0.0470479 | FBN2 |
| 1373 | phototransduction (GO:0007602) | 1/109 | 0.9011464 | 1 | 0 | 0 | 0.4379147 | 0.0455814 | APOB |
| 1374 | cell recognition (GO:0008037) | 1/109 | 0.9011464 | 1 | 0 | 0 | 0.4379147 | 0.0455814 | CATSPERB |
| 1375 | regulation of protein transport (GO:0051223) | 5/379 | 0.9015132 | 1 | 0 | 0 | 0.6297190 | 0.0652896 | CSF3;CHRM1;PTGS2;ALOX15B;STXBP5L |
| 1376 | actin cytoskeleton organization (GO:0030036) | 3/253 | 0.9023500 | 1 | 0 | 0 | 0.5660004 | 0.0581582 | DAAM2;MYLK3;ADRA2A |
| 1377 | negative regulation of cytokine production (GO:0001818) | 2/185 | 0.9023675 | 1 | 0 | 0 | 0.5160292 | 0.0530134 | IRAK3;THBS1 |
| 1378 | cellular response to external stimulus (GO:0071496) | 2/185 | 0.9023675 | 1 | 0 | 0 | 0.5160292 | 0.0530134 | PTGS2;FOXA3 |
| 1379 | ribonucleoside biosynthetic process (GO:0042455) | 1/110 | 0.9032287 | 1 | 0 | 0 | 0.4339336 | 0.0441655 | SLC26A2 |
| 1380 | regulation of cysteine-type endopeptidase activity involved in apoptotic process (GO:0043281) | 2/186 | 0.9040148 | 1 | 0 | 0 | 0.5132548 | 0.0517923 | THBS1;NKX3-1 |
| 1381 | cellular component assembly involved in morphogenesis (GO:0010927) | 2/186 | 0.9040148 | 1 | 0 | 0 | 0.5132548 | 0.0517923 | PCDH15;MYLK3 |
| 1382 | regulation of transmembrane receptor protein serine/threonine kinase signaling pathway (GO:0090092) | 2/186 | 0.9040148 | 1 | 0 | 0 | 0.5132548 | 0.0517923 | FBN2;THBS1 |
| 1383 | response to alkaloid (GO:0043279) | 1/111 | 0.9052673 | 1 | 0 | 0 | 0.4300243 | 0.0427982 | SLC6A1 |
| 1384 | positive regulation of cysteine-type endopeptidase activity involved in apoptotic process (GO:0043280) | 1/111 | 0.9052673 | 1 | 0 | 0 | 0.4300243 | 0.0427982 | NKX3-1 |
| 1385 | synapse organization (GO:0050808) | 1/111 | 0.9052673 | 1 | 0 | 0 | 0.4300243 | 0.0427982 | NTRK2 |
| 1386 | mitochondrial transport (GO:0006839) | 1/111 | 0.9052673 | 1 | 0 | 0 | 0.4300243 | 0.0427982 | BHLHA15 |
| 1387 | hexose metabolic process (GO:0019318) | 2/187 | 0.9056361 | 1 | 0 | 0 | 0.5105101 | 0.0506006 | FUT6;HKDC1 |
| 1388 | regulation of mitosis (GO:0007088) | 1/112 | 0.9072629 | 1 | 0 | 0 | 0.4261848 | 0.0414776 | NEK6 |
| 1389 | regulation of striated muscle tissue development (GO:0016202) | 1/112 | 0.9072629 | 1 | 0 | 0 | 0.4261848 | 0.0414776 | JPH2 |
| 1390 | gonad development (GO:0008406) | 1/112 | 0.9072629 | 1 | 0 | 0 | 0.4261848 | 0.0414776 | NKX3-1 |
| 1391 | regulation of adaptive immune response (GO:0002819) | 1/112 | 0.9072629 | 1 | 0 | 0 | 0.4261848 | 0.0414776 | AZGP1 |
| 1392 | cell junction organization (GO:0034330) | 2/189 | 0.9088024 | 1 | 0 | 0 | 0.5051079 | 0.0483022 | CDH15;FLNC |
| 1393 | regulation of peptidyl-tyrosine phosphorylation (GO:0050730) | 2/189 | 0.9088024 | 1 | 0 | 0 | 0.5051079 | 0.0483022 | CSF3;ADRA2A |
| 1394 | peptide metabolic process (GO:0006518) | 1/113 | 0.9092167 | 1 | 0 | 0 | 0.4224132 | 0.0402018 | CPE |
| 1395 | regulation of muscle tissue development (GO:1901861) | 1/113 | 0.9092167 | 1 | 0 | 0 | 0.4224132 | 0.0402018 | JPH2 |
| 1396 | cell-cell adhesion via plasma-membrane adhesion molecules (GO:0098742) | 2/190 | 0.9103481 | 1 | 0 | 0 | 0.5024494 | 0.0471942 | PCDH15;CDH15 |
| 1397 | regulation of muscle organ development (GO:0048634) | 1/114 | 0.9111294 | 1 | 0 | 0 | 0.4187079 | 0.0389693 | JPH2 |
| 1398 | neuropeptide signaling pathway (GO:0007218) | 1/114 | 0.9111294 | 1 | 0 | 0 | 0.4187079 | 0.0389693 | CPE |
| 1399 | isoprenoid metabolic process (GO:0006720) | 1/114 | 0.9111294 | 1 | 0 | 0 | 0.4187079 | 0.0389693 | APOB |
| 1400 | regulation of axonogenesis (GO:0050770) | 1/114 | 0.9111294 | 1 | 0 | 0 | 0.4187079 | 0.0389693 | NTRK2 |
| 1401 | cell-cell adhesion (GO:0098609) | 2/191 | 0.9118692 | 1 | 0 | 0 | 0.4998188 | 0.0461126 | PCDH15;CDH15 |
| 1402 | regulation of protein catabolic process (GO:0042176) | 3/260 | 0.9120218 | 1 | 0 | 0 | 0.5507619 | 0.0507204 | NEK6;IRAK3;ADRA2A |
| 1403 | cellular cation homeostasis (GO:0030003) | 5/389 | 0.9130524 | 1 | 0 | 0 | 0.6135308 | 0.0558080 | JPH2;C1QTNF1;EDN2;STC1;TNNI3 |
| 1404 | negative regulation of neurogenesis (GO:0050768) | 2/192 | 0.9133661 | 1 | 0 | 0 | 0.4972156 | 0.0450569 | SIX3;PAX6 |
| 1405 | positive regulation of cytokine production (GO:0001819) | 4/327 | 0.9141706 | 1 | 0 | 0 | 0.5838862 | 0.0523968 | PTGS2;ALOX15B;THBS1;ADRA2A |
| 1406 | positive regulation of leukocyte activation (GO:0002696) | 3/262 | 0.9146211 | 1 | 0 | 0 | 0.5465576 | 0.0487777 | ADORA3;ZBTB16;THBS1 |
| 1407 | extracellular matrix disassembly (GO:0022617) | 1/116 | 0.9148349 | 1 | 0 | 0 | 0.4114888 | 0.0366273 | FBN2 |
| 1408 | regulation of proteasomal ubiquitin-dependent protein catabolic process (GO:0032434) | 1/116 | 0.9148349 | 1 | 0 | 0 | 0.4114888 | 0.0366273 | NEK6 |
| 1409 | taxis (GO:0042330) | 3/263 | 0.9158945 | 1 | 0 | 0 | 0.5444794 | 0.0478348 | CCL24;EDN2;CXCL2 |
| 1410 | chemotaxis (GO:0006935) | 3/263 | 0.9158945 | 1 | 0 | 0 | 0.5444794 | 0.0478348 | CCL24;EDN2;CXCL2 |
| 1411 | growth (GO:0040007) | 4/329 | 0.9164779 | 1 | 0 | 0 | 0.5803367 | 0.0506154 | LEFTY1;PCDH15;BMP8A;PTHLH |
| 1412 | cellular amino acid catabolic process (GO:0009063) | 1/117 | 0.9166295 | 1 | 0 | 0 | 0.4079718 | 0.0355147 | ALDH1L2 |
| 1413 | response to UV (GO:0009411) | 1/117 | 0.9166295 | 1 | 0 | 0 | 0.4079718 | 0.0355147 | PTGS2 |
| 1414 | regulation of immune effector process (GO:0002697) | 3/264 | 0.9171505 | 1 | 0 | 0 | 0.5424170 | 0.0469102 | AZGP1;ADORA3;IRAK3 |
| 1415 | regulation of cell cycle phase transition (GO:1901987) | 3/264 | 0.9171505 | 1 | 0 | 0 | 0.5424170 | 0.0469102 | MUC1;NEK6;SIX3 |
| 1416 | muscle contraction (GO:0006936) | 2/195 | 0.9177153 | 1 | 0 | 0 | 0.4895661 | 0.0420381 | EDN2;TNNI3 |
| 1417 | cilium assembly (GO:0042384) | 1/118 | 0.9183864 | 1 | 0 | 0 | 0.4045144 | 0.0344392 | PCDH15 |
| 1418 | negative regulation of protein serine/threonine kinase activity (GO:0071901) | 1/118 | 0.9183864 | 1 | 0 | 0 | 0.4045144 | 0.0344392 | IRAK3 |
| 1419 | positive regulation of leukocyte differentiation (GO:1902107) | 1/118 | 0.9183864 | 1 | 0 | 0 | 0.4045144 | 0.0344392 | ZBTB16 |
| 1420 | positive regulation of stress-activated MAPK cascade (GO:0032874) | 1/118 | 0.9183864 | 1 | 0 | 0 | 0.4045144 | 0.0344392 | WNT16 |
| 1421 | embryonic organ development (GO:0048568) | 1/119 | 0.9201063 | 1 | 0 | 0 | 0.4011151 | 0.0333993 | TPO |
| 1422 | cellular response to extracellular stimulus (GO:0031668) | 1/119 | 0.9201063 | 1 | 0 | 0 | 0.4011151 | 0.0333993 | FOXA3 |
| 1423 | positive regulation of stress-activated protein kinase signaling cascade (GO:0070304) | 1/119 | 0.9201063 | 1 | 0 | 0 | 0.4011151 | 0.0333993 | WNT16 |
| 1424 | nucleoside biosynthetic process (GO:0009163) | 1/119 | 0.9201063 | 1 | 0 | 0 | 0.4011151 | 0.0333993 | SLC26A2 |
| 1425 | positive regulation of cysteine-type endopeptidase activity (GO:2001056) | 1/119 | 0.9201063 | 1 | 0 | 0 | 0.4011151 | 0.0333993 | NKX3-1 |
| 1426 | muscle cell differentiation (GO:0042692) | 1/119 | 0.9201063 | 1 | 0 | 0 | 0.4011151 | 0.0333993 | CDH15 |
| 1427 | regulation of cysteine-type endopeptidase activity (GO:2000116) | 2/197 | 0.9204999 | 1 | 0 | 0 | 0.4845959 | 0.0401431 | THBS1;NKX3-1 |
| 1428 | positive regulation of MAP kinase activity (GO:0043406) | 2/197 | 0.9204999 | 1 | 0 | 0 | 0.4845959 | 0.0401431 | THBS1;ADRA2A |
| 1429 | positive regulation of cell division (GO:0051781) | 1/120 | 0.9217900 | 1 | 0 | 0 | 0.3977725 | 0.0323937 | NKX3-1 |
| 1430 | regulation of cell projection assembly (GO:0060491) | 1/120 | 0.9217900 | 1 | 0 | 0 | 0.3977725 | 0.0323937 | CDC42EP5 |
| 1431 | negative regulation of defense response (GO:0031348) | 1/120 | 0.9217900 | 1 | 0 | 0 | 0.3977725 | 0.0323937 | IRAK3 |
| 1432 | glycosyl compound biosynthetic process (GO:1901659) | 1/120 | 0.9217900 | 1 | 0 | 0 | 0.3977725 | 0.0323937 | SLC26A2 |
| 1433 | transition metal ion homeostasis (GO:0055076) | 1/120 | 0.9217900 | 1 | 0 | 0 | 0.3977725 | 0.0323937 | LCN2 |
| 1434 | energy derivation by oxidation of organic compounds (GO:0015980) | 2/198 | 0.9218588 | 1 | 0 | 0 | 0.4821485 | 0.0392291 | CACNA1E;ADRA2A |
| 1435 | cellular modified amino acid metabolic process (GO:0006575) | 2/199 | 0.9231959 | 1 | 0 | 0 | 0.4797256 | 0.0383367 | TPO;ALDH1L2 |
| 1436 | embryonic organ morphogenesis (GO:0048562) | 1/121 | 0.9234384 | 1 | 0 | 0 | 0.3944851 | 0.0314212 | PAX6 |
| 1437 | detection of light stimulus (GO:0009583) | 1/121 | 0.9234384 | 1 | 0 | 0 | 0.3944851 | 0.0314212 | APOB |
| 1438 | plasma membrane organization (GO:0007009) | 1/121 | 0.9234384 | 1 | 0 | 0 | 0.3944851 | 0.0314212 | ANO7 |
| 1439 | response to temperature stimulus (GO:0009266) | 1/122 | 0.9250521 | 1 | 0 | 0 | 0.3912516 | 0.0304806 | THBS1 |
| 1440 | vitamin metabolic process (GO:0006766) | 1/122 | 0.9250521 | 1 | 0 | 0 | 0.3912516 | 0.0304806 | TCN1 |
| 1441 | toll-like receptor signaling pathway (GO:0002224) | 1/122 | 0.9250521 | 1 | 0 | 0 | 0.3912516 | 0.0304806 | IRAK3 |
| 1442 | cellular ion homeostasis (GO:0006873) | 5/402 | 0.9262719 | 1 | 0 | 0 | 0.5936903 | 0.0454692 | JPH2;C1QTNF1;EDN2;STC1;TNNI3 |
| 1443 | positive regulation of cell activation (GO:0050867) | 3/272 | 0.9266000 | 1 | 0 | 0 | 0.5264636 | 0.0401341 | ADORA3;ZBTB16;THBS1 |
| 1444 | positive regulation of multi-organism process (GO:0043902) | 1/123 | 0.9266318 | 1 | 0 | 0 | 0.3880707 | 0.0295706 | PLAT |
| 1445 | cation homeostasis (GO:0055080) | 6/465 | 0.9269710 | 1 | 0 | 0 | 0.6159058 | 0.0467060 | JPH2;C1QTNF1;EDN2;LCN2;STC1;TNNI3 |
| 1446 | embryonic morphogenesis (GO:0048598) | 5/403 | 0.9272110 | 1 | 0 | 0 | 0.5922171 | 0.0447563 | FBN2;ZBTB16;SIX3;PAX6;CTHRC1 |
| 1447 | regulation of MAP kinase activity (GO:0043405) | 3/273 | 0.9277092 | 1 | 0 | 0 | 0.5245351 | 0.0393595 | IRAK3;THBS1;ADRA2A |
| 1448 | regulation of lymphocyte differentiation (GO:0045619) | 1/124 | 0.9281784 | 1 | 0 | 0 | 0.3849411 | 0.0286902 | ZBTB16 |
| 1449 | sensory perception of sound (GO:0007605) | 1/124 | 0.9281784 | 1 | 0 | 0 | 0.3849411 | 0.0286902 | PCDH15 |
| 1450 | aging (GO:0007568) | 2/204 | 0.9295640 | 1 | 0 | 0 | 0.4679676 | 0.0341802 | NTRK2;WNT16 |
| 1451 | cilium organization (GO:0044782) | 1/125 | 0.9296924 | 1 | 0 | 0 | 0.3818616 | 0.0278383 | PCDH15 |
| 1452 | cytokine-mediated signaling pathway (GO:0019221) | 4/342 | 0.9301713 | 1 | 0 | 0 | 0.5582772 | 0.0404117 | CSF3;EDN2;IL1R2;IRAK3 |
| 1453 | purine ribonucleotide biosynthetic process (GO:0009152) | 1/126 | 0.9311745 | 1 | 0 | 0 | 0.3788309 | 0.0270139 | SLC26A2 |
| 1454 | positive regulation of NF-kappaB transcription factor activity (GO:0051092) | 1/126 | 0.9311745 | 1 | 0 | 0 | 0.3788309 | 0.0270139 | IRAK3 |
| 1455 | cellular response to radiation (GO:0071478) | 1/126 | 0.9311745 | 1 | 0 | 0 | 0.3788309 | 0.0270139 | PTGS2 |
| 1456 | nervous system development (GO:0007399) | 3/277 | 0.9319940 | 1 | 0 | 0 | 0.5169606 | 0.0364090 | SEMA6B;CHRM1;APOB |
| 1457 | response to ionizing radiation (GO:0010212) | 1/127 | 0.9326255 | 1 | 0 | 0 | 0.3758480 | 0.0262160 | CYP17A1 |
| 1458 | sensory perception of mechanical stimulus (GO:0050954) | 1/127 | 0.9326255 | 1 | 0 | 0 | 0.3758480 | 0.0262160 | PCDH15 |
| 1459 | coagulation (GO:0050817) | 6/472 | 0.9328994 | 1 | 0 | 0 | 0.6067716 | 0.0421451 | ITGA10;PLAT;APOB;THBS1;ADRA2A;F5 |
| 1460 | blood coagulation (GO:0007596) | 6/472 | 0.9328994 | 1 | 0 | 0 | 0.6067716 | 0.0421451 | ITGA10;PLAT;APOB;THBS1;ADRA2A;F5 |
| 1461 | organelle assembly (GO:0070925) | 3/278 | 0.9330281 | 1 | 0 | 0 | 0.5151010 | 0.0357068 | NEK6;PCDH15;MYLK3 |
| 1462 | positive regulation of endopeptidase activity (GO:0010950) | 1/128 | 0.9340460 | 1 | 0 | 0 | 0.3729117 | 0.0254436 | NKX3-1 |
| 1463 | fatty acid metabolic process (GO:0006631) | 3/280 | 0.9350530 | 1 | 0 | 0 | 0.5114218 | 0.0343430 | EDN2;PTGS2;ALOX15B |
| 1464 | nucleoside phosphate biosynthetic process (GO:1901293) | 2/209 | 0.9354316 | 1 | 0 | 0 | 0.4567722 | 0.0304883 | SLC26A2;ENTPD8 |
| 1465 | cellular potassium ion transport (GO:0071804) | 1/129 | 0.9354366 | 1 | 0 | 0 | 0.3700209 | 0.0246959 | KCNN2 |
| 1466 | potassium ion transmembrane transport (GO:0071805) | 1/129 | 0.9354366 | 1 | 0 | 0 | 0.3700209 | 0.0246959 | KCNN2 |
| 1467 | regulation of G1/S transition of mitotic cell cycle (GO:2000045) | 1/129 | 0.9354366 | 1 | 0 | 0 | 0.3700209 | 0.0246959 | MUC1 |
| 1468 | organelle localization (GO:0051640) | 1/129 | 0.9354366 | 1 | 0 | 0 | 0.3700209 | 0.0246959 | BHLHA15 |
| 1469 | positive regulation of protein catabolic process (GO:0045732) | 1/130 | 0.9367979 | 1 | 0 | 0 | 0.3671746 | 0.0239720 | ADRA2A |
| 1470 | negative regulation of MAPK cascade (GO:0043409) | 1/130 | 0.9367979 | 1 | 0 | 0 | 0.3671746 | 0.0239720 | IRAK3 |
| 1471 | positive regulation of homeostatic process (GO:0032846) | 1/130 | 0.9367979 | 1 | 0 | 0 | 0.3671746 | 0.0239720 | PTGS2 |
| 1472 | regulation of cytoskeleton organization (GO:0051493) | 4/350 | 0.9375583 | 1 | 0 | 0 | 0.5455165 | 0.0351729 | CCL24;CSF3;CDC42EP5;MYLK3 |
| 1473 | hemostasis (GO:0007599) | 6/478 | 0.9376387 | 1 | 0 | 0 | 0.5991552 | 0.0385800 | ITGA10;PLAT;APOB;THBS1;ADRA2A;F5 |
| 1474 | negative regulation of nervous system development (GO:0051961) | 2/211 | 0.9376466 | 1 | 0 | 0 | 0.4524426 | 0.0291292 | SIX3;PAX6 |
| 1475 | cell division (GO:0051301) | 1/131 | 0.9381306 | 1 | 0 | 0 | 0.3643717 | 0.0232710 | ZBTB16 |
| 1476 | regulation of cell cycle G1/S phase transition (GO:1902806) | 1/131 | 0.9381306 | 1 | 0 | 0 | 0.3643717 | 0.0232710 | MUC1 |
| 1477 | signal transduction by p53 class mediator (GO:0072331) | 1/132 | 0.9394353 | 1 | 0 | 0 | 0.3616113 | 0.0225922 | MUC1 |
| 1478 | purine nucleotide biosynthetic process (GO:0006164) | 1/132 | 0.9394353 | 1 | 0 | 0 | 0.3616113 | 0.0225922 | SLC26A2 |
| 1479 | regulation of I-kappaB kinase/NF-kappaB signaling (GO:0043122) | 2/213 | 0.9397895 | 1 | 0 | 0 | 0.4481943 | 0.0278326 | NEK6;PTGS2 |
| 1480 | alpha-amino acid metabolic process (GO:1901605) | 2/213 | 0.9397895 | 1 | 0 | 0 | 0.4481943 | 0.0278326 | PYCR1;ALDH1L2 |
| 1481 | negative regulation of neuron apoptotic process (GO:0043524) | 1/133 | 0.9407125 | 1 | 0 | 0 | 0.3588925 | 0.0219347 | NTRK2 |
| 1482 | regulation of Wnt signaling pathway (GO:0030111) | 2/214 | 0.9408346 | 1 | 0 | 0 | 0.4461000 | 0.0272067 | SIX3;CTHRC1 |
| 1483 | negative regulation of response to external stimulus (GO:0032102) | 2/215 | 0.9418624 | 1 | 0 | 0 | 0.4440251 | 0.0265954 | C1QTNF1;PLAT |
| 1484 | transforming growth factor beta receptor signaling pathway (GO:0007179) | 1/134 | 0.9419629 | 1 | 0 | 0 | 0.3562142 | 0.0212978 | LEFTY1 |
| 1485 | amine metabolic process (GO:0009308) | 1/134 | 0.9419629 | 1 | 0 | 0 | 0.3562142 | 0.0212978 | SULT1C2 |
| 1486 | regulation of apoptotic signaling pathway (GO:2001233) | 4/356 | 0.9426257 | 1 | 0 | 0 | 0.5363224 | 0.0316892 | MUC1;IL19;THBS1;NKX3-1 |
| 1487 | response to unfolded protein (GO:0006986) | 1/135 | 0.9431869 | 1 | 0 | 0 | 0.3535755 | 0.0206809 | THBS1 |
| 1488 | regulation of proteasomal protein catabolic process (GO:0061136) | 1/135 | 0.9431869 | 1 | 0 | 0 | 0.3535755 | 0.0206809 | NEK6 |
| 1489 | negative regulation of cell activation (GO:0050866) | 1/135 | 0.9431869 | 1 | 0 | 0 | 0.3535755 | 0.0206809 | C1QTNF1 |
| 1490 | cellular response to organic cyclic compound (GO:0071407) | 3/291 | 0.9452165 | 1 | 0 | 0 | 0.4920897 | 0.0277250 | STC1;PTGS2;NKX3-1 |
| 1491 | regulation of cellular carbohydrate metabolic process (GO:0010675) | 1/137 | 0.9455582 | 1 | 0 | 0 | 0.3484138 | 0.0195041 | C1QTNF1 |
| 1492 | regulation of G-protein coupled receptor protein signaling pathway (GO:0008277) | 1/137 | 0.9455582 | 1 | 0 | 0 | 0.3484138 | 0.0195041 | ADRA2A |
| 1493 | regulation of nuclear division (GO:0051783) | 1/138 | 0.9467066 | 1 | 0 | 0 | 0.3458891 | 0.0189430 | NEK6 |
| 1494 | lipid biosynthetic process (GO:0008610) | 6/491 | 0.9469014 | 1 | 0 | 0 | 0.5832916 | 0.0318246 | HSD11B2;EDN2;TFCP2L1;PTGS2;ALOX15B;CYP17A1 |
| 1495 | negative regulation of growth (GO:0045926) | 2/221 | 0.9476823 | 1 | 0 | 0 | 0.4319701 | 0.0232123 | CGREF1;ALOX15B |
| 1496 | monosaccharide metabolic process (GO:0005996) | 2/221 | 0.9476823 | 1 | 0 | 0 | 0.4319701 | 0.0232123 | FUT6;HKDC1 |
| 1497 | positive regulation of peptidase activity (GO:0010952) | 1/139 | 0.9478308 | 1 | 0 | 0 | 0.3434007 | 0.0183992 | NKX3-1 |
| 1498 | neuron differentiation (GO:0030182) | 2/222 | 0.9485967 | 1 | 0 | 0 | 0.4300243 | 0.0226931 | NTRK2;WNT16 |
| 1499 | ribonucleotide biosynthetic process (GO:0009260) | 1/140 | 0.9489314 | 1 | 0 | 0 | 0.3409478 | 0.0178721 | SLC26A2 |
| 1500 | adult behavior (GO:0030534) | 1/141 | 0.9500087 | 1 | 0 | 0 | 0.3385298 | 0.0173612 | PCDH15 |
| 1501 | sodium ion transport (GO:0006814) | 1/141 | 0.9500087 | 1 | 0 | 0 | 0.3385298 | 0.0173612 | SLC13A5 |
| 1502 | branching morphogenesis of an epithelial tube (GO:0048754) | 1/141 | 0.9500087 | 1 | 0 | 0 | 0.3385298 | 0.0173612 | NKX3-1 |
| 1503 | pattern recognition receptor signaling pathway (GO:0002221) | 1/142 | 0.9510635 | 1 | 0 | 0 | 0.3361458 | 0.0168659 | IRAK3 |
| 1504 | regulation of neuron death (GO:1901214) | 2/225 | 0.9512495 | 1 | 0 | 0 | 0.4242906 | 0.0212056 | NTRK2;CSF3 |
| 1505 | response to topologically incorrect protein (GO:0035966) | 1/143 | 0.9520960 | 1 | 0 | 0 | 0.3337951 | 0.0163858 | THBS1 |
| 1506 | ribose phosphate biosynthetic process (GO:0046390) | 1/144 | 0.9531067 | 1 | 0 | 0 | 0.3314771 | 0.0159203 | SLC26A2 |
| 1507 | positive regulation of epithelial cell proliferation (GO:0050679) | 1/144 | 0.9531067 | 1 | 0 | 0 | 0.3314771 | 0.0159203 | CCL24 |
| 1508 | innate immune response-activating signal transduction (GO:0002758) | 1/144 | 0.9531067 | 1 | 0 | 0 | 0.3314771 | 0.0159203 | IRAK3 |
| 1509 | positive regulation of proteolysis (GO:0045862) | 2/228 | 0.9537715 | 1 | 0 | 0 | 0.4187079 | 0.0198179 | ADRA2A;NKX3-1 |
| 1510 | regulation of carbohydrate metabolic process (GO:0006109) | 1/145 | 0.9540962 | 1 | 0 | 0 | 0.3291910 | 0.0154689 | C1QTNF1 |
| 1511 | sulfur compound biosynthetic process (GO:0044272) | 1/145 | 0.9540962 | 1 | 0 | 0 | 0.3291910 | 0.0154689 | SLC26A2 |
| 1512 | response to endoplasmic reticulum stress (GO:0034976) | 1/145 | 0.9540962 | 1 | 0 | 0 | 0.3291910 | 0.0154689 | THBS1 |
| 1513 | negative regulation of cellular catabolic process (GO:0031330) | 1/145 | 0.9540962 | 1 | 0 | 0 | 0.3291910 | 0.0154689 | TNNI3 |
| 1514 | purine-containing compound biosynthetic process (GO:0072522) | 1/146 | 0.9550649 | 1 | 0 | 0 | 0.3269363 | 0.0150312 | SLC26A2 |
| 1515 | protein homooligomerization (GO:0051260) | 2/230 | 0.9553831 | 1 | 0 | 0 | 0.4150669 | 0.0189449 | C1QTNF1;SLC6A1 |
| 1516 | regulation of establishment of protein localization (GO:0070201) | 5/442 | 0.9564577 | 1 | 0 | 0 | 0.5399626 | 0.0240385 | CSF3;CHRM1;PTGS2;ALOX15B;STXBP5L |
| 1517 | lipid catabolic process (GO:0016042) | 2/232 | 0.9569409 | 1 | 0 | 0 | 0.4114888 | 0.0181111 | LIPG;APOB |
| 1518 | regulation of proteolysis involved in cellular protein catabolic process (GO:1903050) | 1/148 | 0.9569415 | 1 | 0 | 0 | 0.3225182 | 0.0141950 | NEK6 |
| 1519 | regulation of JNK cascade (GO:0046328) | 1/148 | 0.9569415 | 1 | 0 | 0 | 0.3225182 | 0.0141950 | WNT16 |
| 1520 | regulation of cell-substrate adhesion (GO:0010810) | 1/149 | 0.9578502 | 1 | 0 | 0 | 0.3203537 | 0.0137957 | THBS1 |
| 1521 | positive regulation of Rho GTPase activity (GO:0032321) | 1/149 | 0.9578502 | 1 | 0 | 0 | 0.3203537 | 0.0137957 | CCL24 |
| 1522 | regulation of cell division (GO:0051302) | 2/234 | 0.9584467 | 1 | 0 | 0 | 0.4079718 | 0.0173149 | NEK6;NKX3-1 |
| 1523 | Wnt signaling pathway (GO:0016055) | 2/234 | 0.9584467 | 1 | 0 | 0 | 0.4079718 | 0.0173149 | WNT16;CTHRC1 |
| 1524 | negative regulation of cell growth (GO:0030308) | 1/150 | 0.9587398 | 1 | 0 | 0 | 0.3182180 | 0.0134083 | CGREF1 |
| 1525 | single organismal cell-cell adhesion (GO:0016337) | 2/235 | 0.9591806 | 1 | 0 | 0 | 0.4062357 | 0.0169302 | CDSN;CEACAM5 |
| 1526 | potassium ion transport (GO:0006813) | 1/151 | 0.9596107 | 1 | 0 | 0 | 0.3161106 | 0.0130325 | KCNN2 |
| 1527 | activation of innate immune response (GO:0002218) | 1/151 | 0.9596107 | 1 | 0 | 0 | 0.3161106 | 0.0130325 | IRAK3 |
| 1528 | negative regulation of immune system process (GO:0002683) | 3/311 | 0.9600120 | 1 | 0 | 0 | 0.4604440 | 0.0187905 | ZBTB16;IRAK3;THBS1 |
| 1529 | peptidyl-tyrosine phosphorylation (GO:0018108) | 1/152 | 0.9604633 | 1 | 0 | 0 | 0.3140309 | 0.0126679 | NTRK2 |
| 1530 | regulation of canonical Wnt signaling pathway (GO:0060828) | 1/152 | 0.9604633 | 1 | 0 | 0 | 0.3140309 | 0.0126679 | CTHRC1 |
| 1531 | maintenance of location (GO:0051235) | 1/152 | 0.9604633 | 1 | 0 | 0 | 0.3140309 | 0.0126679 | FBN2 |
| 1532 | receptor-mediated endocytosis (GO:0006898) | 1/152 | 0.9604633 | 1 | 0 | 0 | 0.3140309 | 0.0126679 | APOB |
| 1533 | muscle system process (GO:0003012) | 2/237 | 0.9606113 | 1 | 0 | 0 | 0.4028076 | 0.0161870 | EDN2;TNNI3 |
| 1534 | regulation of homeostatic process (GO:0032844) | 3/314 | 0.9618780 | 1 | 0 | 0 | 0.4560449 | 0.0177254 | BMP8A;PTGS2;ADRA2A |
| 1535 | negative regulation of cell development (GO:0010721) | 2/239 | 0.9619939 | 1 | 0 | 0 | 0.3994368 | 0.0154771 | SIX3;PAX6 |
| 1536 | peptidyl-tyrosine modification (GO:0018212) | 1/154 | 0.9621149 | 1 | 0 | 0 | 0.3099526 | 0.0119708 | NTRK2 |
| 1537 | positive regulation of protein processing (GO:0010954) | 2/240 | 0.9626676 | 1 | 0 | 0 | 0.3977725 | 0.0151341 | ADRA2A;NKX3-1 |
| 1538 | positive regulation of protein maturation (GO:1903319) | 2/240 | 0.9626676 | 1 | 0 | 0 | 0.3977725 | 0.0151341 | ADRA2A;NKX3-1 |
| 1539 | mitotic nuclear division (GO:0007067) | 2/240 | 0.9626676 | 1 | 0 | 0 | 0.3977725 | 0.0151341 | NEK6;FIGN |
| 1540 | regulation of cellular protein catabolic process (GO:1903362) | 1/155 | 0.9629147 | 1 | 0 | 0 | 0.3079529 | 0.0116377 | NEK6 |
| 1541 | cell cycle checkpoint (GO:0000075) | 1/156 | 0.9636976 | 1 | 0 | 0 | 0.3059788 | 0.0113144 | NEK6 |
| 1542 | regulation of myeloid cell differentiation (GO:0045637) | 1/156 | 0.9636976 | 1 | 0 | 0 | 0.3059788 | 0.0113144 | ZBTB16 |
| 1543 | negative regulation of phosphorus metabolic process (GO:0010563) | 5/458 | 0.9649916 | 1 | 0 | 0 | 0.5210993 | 0.0185698 | AHSG;GRM8;TNNI3;IRAK3;ADRA2A |
| 1544 | negative regulation of phosphate metabolic process (GO:0045936) | 5/458 | 0.9649916 | 1 | 0 | 0 | 0.5210993 | 0.0185698 | AHSG;GRM8;TNNI3;IRAK3;ADRA2A |
| 1545 | regulation of mitotic cell cycle (GO:0007346) | 4/391 | 0.9654132 | 1 | 0 | 0 | 0.4883140 | 0.0171882 | MUC1;BRINP1;NEK6;NKX3-1 |
| 1546 | cellular response to hormone stimulus (GO:0032870) | 5/462 | 0.9668704 | 1 | 0 | 0 | 0.5165876 | 0.0174043 | STC1;APOB;ADRA2A;NKX3-1;CYP17A1 |
| 1547 | small molecule biosynthetic process (GO:0044283) | 4/394 | 0.9669123 | 1 | 0 | 0 | 0.4845959 | 0.0163054 | EDN2;PYCR1;PTGS2;ALOX15B |
| 1548 | regulation of intracellular transport (GO:0032386) | 4/394 | 0.9669123 | 1 | 0 | 0 | 0.4845959 | 0.0163054 | CSF3;CHRM1;ADORA3;PTGS2 |
| 1549 | endocytosis (GO:0006897) | 3/323 | 0.9669972 | 1 | 0 | 0 | 0.4433377 | 0.0148783 | AHSG;ELMOD1;APOB |
| 1550 | protein dephosphorylation (GO:0006470) | 1/161 | 0.9673719 | 1 | 0 | 0 | 0.2964764 | 0.0098348 | PTPRH |
| 1551 | cell-cell junction organization (GO:0045216) | 1/161 | 0.9673719 | 1 | 0 | 0 | 0.2964764 | 0.0098348 | CDH15 |
| 1552 | regulation of cell morphogenesis involved in differentiation (GO:0010769) | 2/248 | 0.9676601 | 1 | 0 | 0 | 0.3849411 | 0.0126547 | NTRK2;CUX2 |
| 1553 | morphogenesis of a branching epithelium (GO:0061138) | 1/162 | 0.9680609 | 1 | 0 | 0 | 0.2946463 | 0.0095643 | NKX3-1 |
| 1554 | glycosaminoglycan metabolic process (GO:0030203) | 1/162 | 0.9680609 | 1 | 0 | 0 | 0.2946463 | 0.0095643 | SLC26A2 |
| 1555 | developmental growth (GO:0048589) | 1/163 | 0.9687355 | 1 | 0 | 0 | 0.2928386 | 0.0093016 | PTHLH |
| 1556 | response to virus (GO:0009615) | 2/250 | 0.9688041 | 1 | 0 | 0 | 0.3818616 | 0.0121023 | IRAK3;APOB |
| 1557 | regulation of mitotic cell cycle phase transition (GO:1901990) | 2/251 | 0.9693615 | 1 | 0 | 0 | 0.3803402 | 0.0118353 | MUC1;NEK6 |
| 1558 | rhythmic process (GO:0048511) | 2/252 | 0.9699092 | 1 | 0 | 0 | 0.3788309 | 0.0115744 | NTRK2;SIX3 |
| 1559 | activation of protein kinase activity (GO:0032147) | 2/252 | 0.9699092 | 1 | 0 | 0 | 0.3788309 | 0.0115744 | THBS1;ADRA2A |
| 1560 | cellular carbohydrate metabolic process (GO:0044262) | 1/165 | 0.9700422 | 1 | 0 | 0 | 0.2892891 | 0.0087989 | HKDC1 |
| 1561 | regulation of endocytosis (GO:0030100) | 1/165 | 0.9700422 | 1 | 0 | 0 | 0.2892891 | 0.0087989 | AHSG |
| 1562 | response to transforming growth factor beta (GO:0071559) | 1/166 | 0.9706750 | 1 | 0 | 0 | 0.2875464 | 0.0085584 | LEFTY1 |
| 1563 | cellular response to transforming growth factor beta stimulus (GO:0071560) | 1/166 | 0.9706750 | 1 | 0 | 0 | 0.2875464 | 0.0085584 | LEFTY1 |
| 1564 | organic hydroxy compound biosynthetic process (GO:1901617) | 1/166 | 0.9706750 | 1 | 0 | 0 | 0.2875464 | 0.0085584 | GPR37 |
| 1565 | monocarboxylic acid metabolic process (GO:0032787) | 5/473 | 0.9715686 | 1 | 0 | 0 | 0.5045740 | 0.0145536 | EDN2;HKDC1;SLCO1B3;PTGS2;ALOX15B |
| 1566 | organ morphogenesis (GO:0009887) | 4/405 | 0.9719072 | 1 | 0 | 0 | 0.4714340 | 0.0134335 | COMP;LEFTY1;CDSN;PAX6 |
| 1567 | epithelium development (GO:0060429) | 2/256 | 0.9720074 | 1 | 0 | 0 | 0.3729117 | 0.0105877 | CDSN;PTHLH |
| 1568 | positive regulation of protein serine/threonine kinase activity (GO:0071902) | 2/257 | 0.9725095 | 1 | 0 | 0 | 0.3714607 | 0.0103546 | THBS1;ADRA2A |
| 1569 | organic hydroxy compound metabolic process (GO:1901615) | 5/476 | 0.9727386 | 1 | 0 | 0 | 0.5013939 | 0.0138585 | TPO;GPR37;SLCO1B3;APOB;CYP17A1 |
| 1570 | MAPK cascade (GO:0000165) | 1/170 | 0.9730755 | 1 | 0 | 0 | 0.2807806 | 0.0076635 | CDC42EP5 |
| 1571 | morphogenesis of a branching structure (GO:0001763) | 1/170 | 0.9730755 | 1 | 0 | 0 | 0.2807806 | 0.0076635 | NKX3-1 |
| 1572 | regulation of stress-activated MAPK cascade (GO:0032872) | 1/170 | 0.9730755 | 1 | 0 | 0 | 0.2807806 | 0.0076635 | WNT16 |
| 1573 | regulation of cell morphogenesis (GO:0022604) | 4/408 | 0.9731419 | 1 | 0 | 0 | 0.4679676 | 0.0127406 | CCL24;NTRK2;CUX2;CDC42EP5 |
| 1574 | regulation of cell adhesion (GO:0030155) | 3/336 | 0.9732599 | 1 | 0 | 0 | 0.4261848 | 0.0115514 | ADAMDEC1;C1QTNF1;THBS1 |
| 1575 | single organism cell adhesion (GO:0098602) | 2/259 | 0.9734878 | 1 | 0 | 0 | 0.3685923 | 0.0099041 | CDSN;CEACAM5 |
| 1576 | aminoglycan metabolic process (GO:0006022) | 1/171 | 0.9736444 | 1 | 0 | 0 | 0.2791386 | 0.0074556 | SLC26A2 |
| 1577 | regulation of stress-activated protein kinase signaling cascade (GO:0070302) | 1/171 | 0.9736444 | 1 | 0 | 0 | 0.2791386 | 0.0074556 | WNT16 |
| 1578 | positive regulation of cell adhesion (GO:0045785) | 1/171 | 0.9736444 | 1 | 0 | 0 | 0.2791386 | 0.0074556 | THBS1 |
| 1579 | regulation of chromosome organization (GO:0033044) | 1/172 | 0.9742013 | 1 | 0 | 0 | 0.2775157 | 0.0072535 | MUC1 |
| 1580 | regulation of cytokine production (GO:0001817) | 5/482 | 0.9749458 | 1 | 0 | 0 | 0.4951525 | 0.0125637 | IRAK3;PTGS2;ALOX15B;THBS1;ADRA2A |
| 1581 | reproductive structure development (GO:0048608) | 2/265 | 0.9762254 | 1 | 0 | 0 | 0.3602468 | 0.0086682 | ALOX15B;NKX3-1 |
| 1582 | cellular amide metabolic process (GO:0043603) | 1/177 | 0.9768143 | 1 | 0 | 0 | 0.2696763 | 0.0063262 | CPE |
| 1583 | negative regulation of intracellular signal transduction (GO:1902532) | 3/345 | 0.9769175 | 1 | 0 | 0 | 0.4150669 | 0.0096931 | MUC1;IRAK3;THBS1 |
| 1584 | regulation of cellular ketone metabolic process (GO:0010565) | 1/178 | 0.9773044 | 1 | 0 | 0 | 0.2681612 | 0.0061562 | PTGS2 |
| 1585 | regulation of cell activation (GO:0050865) | 4/420 | 0.9775904 | 1 | 0 | 0 | 0.4545971 | 0.0103032 | C1QTNF1;ADORA3;ZBTB16;THBS1 |
| 1586 | mitochondrion organization (GO:0007005) | 1/179 | 0.9777841 | 1 | 0 | 0 | 0.2666631 | 0.0059910 | BHLHA15 |
| 1587 | protein catabolic process (GO:0030163) | 2/269 | 0.9778966 | 1 | 0 | 0 | 0.3548899 | 0.0079323 | PRSS16;APOB |
| 1588 | multicellular organismal reproductive process (GO:0048609) | 5/491 | 0.9779472 | 1 | 0 | 0 | 0.4860763 | 0.0108393 | CATSPERB;PTGS2;APOB;FOXA3;CYP17A1 |
| 1589 | locomotory behavior (GO:0007626) | 1/183 | 0.9796038 | 1 | 0 | 0 | 0.2608344 | 0.0053750 | PCDH15 |
| 1590 | spermatogenesis (GO:0007283) | 3/353 | 0.9797652 | 1 | 0 | 0 | 0.4056603 | 0.0082927 | CATSPERB;APOB;FOXA3 |
| 1591 | male gamete generation (GO:0048232) | 3/354 | 0.9800967 | 1 | 0 | 0 | 0.4045144 | 0.0081324 | CATSPERB;APOB;FOXA3 |
| 1592 | regulation of neuron projection development (GO:0010975) | 2/275 | 0.9801922 | 1 | 0 | 0 | 0.3471469 | 0.0069452 | NTRK2;CUX2 |
| 1593 | antigen processing and presentation of peptide antigen (GO:0048002) | 1/185 | 0.9804571 | 1 | 0 | 0 | 0.2580146 | 0.0050923 | AZGP1 |
| 1594 | DNA replication (GO:0006260) | 1/186 | 0.9808703 | 1 | 0 | 0 | 0.2566274 | 0.0049568 | ADRA2A |
| 1595 | intracellular receptor signaling pathway (GO:0030522) | 1/186 | 0.9808703 | 1 | 0 | 0 | 0.2566274 | 0.0049568 | NKX3-1 |
| 1596 | positive regulation of cell cycle (GO:0045787) | 2/278 | 0.9812518 | 1 | 0 | 0 | 0.3434007 | 0.0064993 | MUC1;NKX3-1 |
| 1597 | brain development (GO:0007420) | 1/187 | 0.9812747 | 1 | 0 | 0 | 0.2552551 | 0.0048250 | SIX3 |
| 1598 | tissue morphogenesis (GO:0048729) | 3/358 | 0.9813716 | 1 | 0 | 0 | 0.3999947 | 0.0075215 | PCDH15;TNNI3;NKX3-1 |
| 1599 | regulation of neuron apoptotic process (GO:0043523) | 1/188 | 0.9816707 | 1 | 0 | 0 | 0.2538973 | 0.0046969 | NTRK2 |
| 1600 | positive regulation of growth (GO:0045927) | 1/189 | 0.9820583 | 1 | 0 | 0 | 0.2525540 | 0.0045724 | TFCP2L1 |
| 1601 | positive regulation of T cell activation (GO:0050870) | 1/189 | 0.9820583 | 1 | 0 | 0 | 0.2525540 | 0.0045724 | ZBTB16 |
| 1602 | negative regulation of protein kinase activity (GO:0006469) | 1/189 | 0.9820583 | 1 | 0 | 0 | 0.2525540 | 0.0045724 | IRAK3 |
| 1603 | positive regulation of innate immune response (GO:0045089) | 1/190 | 0.9824377 | 1 | 0 | 0 | 0.2512247 | 0.0044513 | IRAK3 |
| 1604 | cellular component morphogenesis (GO:0032989) | 4/437 | 0.9827203 | 1 | 0 | 0 | 0.4369126 | 0.0076157 | STC1;TFCP2L1;SHROOM1;WNT16 |
| 1605 | response to peptide hormone (GO:0043434) | 3/364 | 0.9831391 | 1 | 0 | 0 | 0.3934013 | 0.0066897 | HSD11B2;TFF1;PLAT |
| 1606 | negative regulation of mitotic cell cycle phase transition (GO:1901991) | 1/192 | 0.9831727 | 1 | 0 | 0 | 0.2486078 | 0.0042190 | MUC1 |
| 1607 | small GTPase mediated signal transduction (GO:0007264) | 4/439 | 0.9832450 | 1 | 0 | 0 | 0.4349221 | 0.0073489 | RAB43;ARHGAP40;CDC42EP5;ADRA2A |
| 1608 | transmembrane receptor protein serine/threonine kinase signaling pathway (GO:0007178) | 1/196 | 0.9845518 | 1 | 0 | 0 | 0.2435342 | 0.0037915 | LEFTY1 |
| 1609 | coenzyme metabolic process (GO:0006732) | 1/196 | 0.9845518 | 1 | 0 | 0 | 0.2435342 | 0.0037915 | ALDH1L2 |
| 1610 | carboxylic acid catabolic process (GO:0046395) | 1/200 | 0.9858182 | 1 | 0 | 0 | 0.2386635 | 0.0034089 | ALDH1L2 |
| 1611 | organic acid catabolic process (GO:0016054) | 1/200 | 0.9858182 | 1 | 0 | 0 | 0.2386635 | 0.0034089 | ALDH1L2 |
| 1612 | negative regulation of cell cycle phase transition (GO:1901988) | 1/200 | 0.9858182 | 1 | 0 | 0 | 0.2386635 | 0.0034089 | MUC1 |
| 1613 | generation of precursor metabolites and energy (GO:0006091) | 3/375 | 0.9859716 | 1 | 0 | 0 | 0.3818616 | 0.0053948 | HKDC1;CACNA1E;ADRA2A |
| 1614 | negative regulation of kinase activity (GO:0033673) | 1/202 | 0.9864119 | 1 | 0 | 0 | 0.2363005 | 0.0032329 | IRAK3 |
| 1615 | signal transduction by phosphorylation (GO:0023014) | 1/202 | 0.9864119 | 1 | 0 | 0 | 0.2363005 | 0.0032329 | CDC42EP5 |
| 1616 | morphogenesis of an epithelium (GO:0002009) | 2/296 | 0.9865454 | 1 | 0 | 0 | 0.3225182 | 0.0043688 | PCDH15;NKX3-1 |
| 1617 | nuclear division (GO:0000280) | 2/298 | 0.9870350 | 1 | 0 | 0 | 0.3203537 | 0.0041806 | NEK6;FIGN |
| 1618 | response to peptide (GO:1901652) | 3/384 | 0.9879443 | 1 | 0 | 0 | 0.3729117 | 0.0045230 | HSD11B2;TFF1;PLAT |
| 1619 | nucleotide biosynthetic process (GO:0009165) | 1/208 | 0.9880485 | 1 | 0 | 0 | 0.2294841 | 0.0027592 | SLC26A2 |
| 1620 | regulation of leukocyte differentiation (GO:1902105) | 1/210 | 0.9885491 | 1 | 0 | 0 | 0.2272986 | 0.0026178 | ZBTB16 |
| 1621 | nitrogen compound transport (GO:0071705) | 4/464 | 0.9886529 | 1 | 0 | 0 | 0.4114888 | 0.0046959 | NTRK2;TCN1;ADORA3;SLC6A1 |
| 1622 | regulation of leukocyte activation (GO:0002694) | 3/390 | 0.9891084 | 1 | 0 | 0 | 0.3671746 | 0.0040210 | ADORA3;ZBTB16;THBS1 |
| 1623 | gamete generation (GO:0007276) | 3/390 | 0.9891084 | 1 | 0 | 0 | 0.3671746 | 0.0040210 | CATSPERB;APOB;FOXA3 |
| 1624 | cell projection assembly (GO:0030031) | 1/213 | 0.9892610 | 1 | 0 | 0 | 0.2240972 | 0.0024196 | PCDH15 |
| 1625 | regulation of cell projection organization (GO:0031344) | 3/391 | 0.9892916 | 1 | 0 | 0 | 0.3662355 | 0.0039429 | NTRK2;CUX2;CDC42EP5 |
| 1626 | positive regulation of sequence-specific DNA binding transcription factor activity (GO:0051091) | 1/214 | 0.9894884 | 1 | 0 | 0 | 0.2230500 | 0.0023570 | IRAK3 |
| 1627 | transcription from RNA polymerase II promoter (GO:0006366) | 4/470 | 0.9896779 | 1 | 0 | 0 | 0.4062357 | 0.0042150 | SIX3;PAX6;SPDEF;NKX3-1 |
| 1628 | sulfur compound metabolic process (GO:0006790) | 2/314 | 0.9903742 | 1 | 0 | 0 | 0.3040299 | 0.0029407 | SULT1C2;SLC26A2 |
| 1629 | positive regulation of cell cycle process (GO:0090068) | 1/220 | 0.9907551 | 1 | 0 | 0 | 0.2169668 | 0.0020152 | MUC1 |
| 1630 | protein folding (GO:0006457) | 1/221 | 0.9909508 | 1 | 0 | 0 | 0.2159851 | 0.0019634 | FKBP5 |
| 1631 | in utero embryonic development (GO:0001701) | 1/222 | 0.9911425 | 1 | 0 | 0 | 0.2150121 | 0.0019130 | APOB |
| 1632 | antigen processing and presentation (GO:0019882) | 1/225 | 0.9916935 | 1 | 0 | 0 | 0.2121453 | 0.0017696 | AZGP1 |
| 1633 | response to light stimulus (GO:0009416) | 2/322 | 0.9917129 | 1 | 0 | 0 | 0.2964764 | 0.0024672 | APOB;PTGS2 |
| 1634 | chordate embryonic development (GO:0043009) | 1/226 | 0.9918694 | 1 | 0 | 0 | 0.2112066 | 0.0017243 | APOB |
| 1635 | negative regulation of phosphorylation (GO:0042326) | 2/325 | 0.9921666 | 1 | 0 | 0 | 0.2937397 | 0.0023101 | AHSG;IRAK3 |
| 1636 | organelle fission (GO:0048285) | 2/325 | 0.9921666 | 1 | 0 | 0 | 0.2937397 | 0.0023101 | NEK6;FIGN |
| 1637 | cellular process involved in reproduction in multicellular organism (GO:0022412) | 1/228 | 0.9922102 | 1 | 0 | 0 | 0.2093539 | 0.0016372 | ZBTB16 |
| 1638 | embryo development ending in birth or egg hatching (GO:0009792) | 1/230 | 0.9925368 | 1 | 0 | 0 | 0.2075335 | 0.0015547 | APOB |
| 1639 | nucleic acid phosphodiester bond hydrolysis (GO:0090305) | 1/230 | 0.9925368 | 1 | 0 | 0 | 0.2075335 | 0.0015547 | AZGP1 |
| 1640 | cellular response to abiotic stimulus (GO:0071214) | 1/232 | 0.9928497 | 1 | 0 | 0 | 0.2057444 | 0.0014764 | PTGS2 |
| 1641 | regulation of protein serine/threonine kinase activity (GO:0071900) | 3/416 | 0.9930174 | 1 | 0 | 0 | 0.3442262 | 0.0024120 | IRAK3;THBS1;ADRA2A |
| 1642 | cellular amino acid metabolic process (GO:0006520) | 3/421 | 0.9935946 | 1 | 0 | 0 | 0.3401380 | 0.0021857 | TPO;PYCR1;ALDH1L2 |
| 1643 | regulation of sequence-specific DNA binding transcription factor activity (GO:0051090) | 2/338 | 0.9938674 | 1 | 0 | 0 | 0.2824420 | 0.0017374 | IRAK3;PTHLH |
| 1644 | alcohol metabolic process (GO:0006066) | 2/340 | 0.9940947 | 1 | 0 | 0 | 0.2807806 | 0.0016630 | APOB;CYP17A1 |
| 1645 | GTP catabolic process (GO:0006184) | 1/243 | 0.9943507 | 1 | 0 | 0 | 0.1964309 | 0.0011129 | RAB43 |
| 1646 | positive regulation of lymphocyte activation (GO:0051251) | 1/243 | 0.9943507 | 1 | 0 | 0 | 0.1964309 | 0.0011129 | ZBTB16 |
| 1647 | microtubule cytoskeleton organization (GO:0000226) | 1/245 | 0.9945876 | 1 | 0 | 0 | 0.1948273 | 0.0010573 | NEK6 |
| 1648 | guanosine-containing compound catabolic process (GO:1901069) | 1/246 | 0.9947024 | 1 | 0 | 0 | 0.1940354 | 0.0010307 | RAB43 |
| 1649 | response to insulin (GO:0032868) | 1/246 | 0.9947024 | 1 | 0 | 0 | 0.1940354 | 0.0010307 | HSD11B2 |
| 1650 | regulation of Ras GTPase activity (GO:0032318) | 2/349 | 0.9950197 | 1 | 0 | 0 | 0.2735398 | 0.0013657 | CCL24;NTRK2 |
| 1651 | cellular component disassembly (GO:0022411) | 2/350 | 0.9951133 | 1 | 0 | 0 | 0.2727583 | 0.0013362 | FBN2;NEK6 |
| 1652 | leukocyte differentiation (GO:0002521) | 1/251 | 0.9952406 | 1 | 0 | 0 | 0.1901701 | 0.0009072 | CSF3 |
| 1653 | inorganic cation transmembrane transport (GO:0098662) | 3/440 | 0.9953955 | 1 | 0 | 0 | 0.3254502 | 0.0015020 | JPH2;KCNN2;CACNA1E |
| 1654 | regulation of innate immune response (GO:0045088) | 1/254 | 0.9955370 | 1 | 0 | 0 | 0.1879240 | 0.0008406 | IRAK3 |
| 1655 | negative regulation of cell cycle process (GO:0010948) | 1/254 | 0.9955370 | 1 | 0 | 0 | 0.1879240 | 0.0008406 | MUC1 |
| 1656 | response to radiation (GO:0009314) | 3/442 | 0.9955537 | 1 | 0 | 0 | 0.3239776 | 0.0014437 | PTGS2;APOB;CYP17A1 |
| 1657 | cofactor metabolic process (GO:0051186) | 1/255 | 0.9956317 | 1 | 0 | 0 | 0.1871870 | 0.0008195 | ALDH1L2 |
| 1658 | regulation of small GTPase mediated signal transduction (GO:0051056) | 1/256 | 0.9957243 | 1 | 0 | 0 | 0.1864558 | 0.0007989 | ARHGAP40 |
| 1659 | GTP metabolic process (GO:0046039) | 1/258 | 0.9959038 | 1 | 0 | 0 | 0.1850105 | 0.0007594 | RAB43 |
| 1660 | regulation of T cell activation (GO:0050863) | 1/259 | 0.9959906 | 1 | 0 | 0 | 0.1842961 | 0.0007404 | ZBTB16 |
| 1661 | negative regulation of protein phosphorylation (GO:0001933) | 1/260 | 0.9960757 | 1 | 0 | 0 | 0.1835873 | 0.0007219 | IRAK3 |
| 1662 | small molecule catabolic process (GO:0044282) | 1/261 | 0.9961589 | 1 | 0 | 0 | 0.1828839 | 0.0007038 | ALDH1L2 |
| 1663 | protein oligomerization (GO:0051259) | 2/366 | 0.9963958 | 1 | 0 | 0 | 0.2608344 | 0.0009418 | C1QTNF1;SLC6A1 |
| 1664 | regulation of translation (GO:0006417) | 1/264 | 0.9963982 | 1 | 0 | 0 | 0.1808057 | 0.0006524 | THBS1 |
| 1665 | positive regulation of protein kinase activity (GO:0045860) | 3/456 | 0.9965219 | 1 | 0 | 0 | 0.3140309 | 0.0010941 | THBS1;ADRA2A;NKX3-1 |
| 1666 | methylation (GO:0032259) | 1/269 | 0.9967644 | 1 | 0 | 0 | 0.1774450 | 0.0005751 | ALDH1L2 |
| 1667 | guanosine-containing compound metabolic process (GO:1901068) | 1/269 | 0.9967644 | 1 | 0 | 0 | 0.1774450 | 0.0005751 | RAB43 |
| 1668 | carbohydrate derivative biosynthetic process (GO:1901137) | 2/377 | 0.9970793 | 1 | 0 | 0 | 0.2532239 | 0.0007407 | SLC26A2;B3GNT6 |
| 1669 | neurotrophin TRK receptor signaling pathway (GO:0048011) | 1/274 | 0.9970934 | 1 | 0 | 0 | 0.1742069 | 0.0005071 | NTRK2 |
| 1670 | embryo development (GO:0009790) | 1/276 | 0.9972154 | 1 | 0 | 0 | 0.1729446 | 0.0004822 | APOB |
| 1671 | protein localization to membrane (GO:0072657) | 1/276 | 0.9972154 | 1 | 0 | 0 | 0.1729446 | 0.0004822 | CPE |
| 1672 | neurotrophin signaling pathway (GO:0038179) | 1/278 | 0.9973324 | 1 | 0 | 0 | 0.1717003 | 0.0004586 | NTRK2 |
| 1673 | dephosphorylation (GO:0016311) | 1/278 | 0.9973324 | 1 | 0 | 0 | 0.1717003 | 0.0004586 | PTPRH |
| 1674 | monovalent inorganic cation transport (GO:0015672) | 2/384 | 0.9974461 | 1 | 0 | 0 | 0.2486078 | 0.0006357 | KCNN2;SLC13A5 |
| 1675 | negative regulation of transferase activity (GO:0051348) | 1/284 | 0.9976546 | 1 | 0 | 0 | 0.1680729 | 0.0003947 | IRAK3 |
| 1676 | positive regulation of kinase activity (GO:0033674) | 3/480 | 0.9977258 | 1 | 0 | 0 | 0.2983294 | 0.0006792 | THBS1;ADRA2A;NKX3-1 |
| 1677 | regulation of cell cycle process (GO:0010564) | 3/481 | 0.9977659 | 1 | 0 | 0 | 0.2977091 | 0.0006658 | MUC1;NEK6;SIX3 |
| 1678 | positive regulation of GTPase activity (GO:0043547) | 3/482 | 0.9978054 | 1 | 0 | 0 | 0.2970915 | 0.0006527 | CCL24;ARHGAP40;ELMOD1 |
| 1679 | positive regulation of GTP catabolic process (GO:0033126) | 3/483 | 0.9978441 | 1 | 0 | 0 | 0.2964764 | 0.0006399 | CCL24;ARHGAP40;ELMOD1 |
| 1680 | phospholipid metabolic process (GO:0006644) | 1/288 | 0.9978475 | 1 | 0 | 0 | 0.1657385 | 0.0003571 | LIPG |
| 1681 | protein localization to organelle (GO:0033365) | 2/396 | 0.9979723 | 1 | 0 | 0 | 0.2410742 | 0.0004893 | ZBTB16;PAX6 |
| 1682 | positive regulation of Ras GTPase activity (GO:0032320) | 1/292 | 0.9980245 | 1 | 0 | 0 | 0.1634681 | 0.0003233 | CCL24 |
| 1683 | glycerolipid metabolic process (GO:0046486) | 1/296 | 0.9981870 | 1 | 0 | 0 | 0.1612591 | 0.0002926 | APOB |
| 1684 | cellular response to organonitrogen compound (GO:0071417) | 2/411 | 0.9984821 | 1 | 0 | 0 | 0.2322759 | 0.0003528 | STC1;PTGS2 |
| 1685 | regulation of multi-organism process (GO:0043900) | 1/306 | 0.9985371 | 1 | 0 | 0 | 0.1559892 | 0.0002284 | PLAT |
| 1686 | nucleoside monophosphate metabolic process (GO:0009123) | 2/427 | 0.9988868 | 1 | 0 | 0 | 0.2235724 | 0.0002490 | RTEL1-TNFRSF6B;ENTPD8 |
| 1687 | regulation of cell growth (GO:0001558) | 1/322 | 0.9989623 | 1 | 0 | 0 | 0.1482382 | 0.0001539 | CGREF1 |
| 1688 | organophosphate biosynthetic process (GO:0090407) | 2/436 | 0.9990655 | 1 | 0 | 0 | 0.2189573 | 0.0002047 | SLC26A2;ENTPD8 |
| 1689 | ATP catabolic process (GO:0006200) | 1/327 | 0.9990679 | 1 | 0 | 0 | 0.1459716 | 0.0001361 | RTEL1-TNFRSF6B |
| 1690 | cellular response to nitrogen compound (GO:1901699) | 2/438 | 0.9991012 | 1 | 0 | 0 | 0.2179575 | 0.0001960 | STC1;PTGS2 |
| 1691 | purine ribonucleoside monophosphate catabolic process (GO:0009169) | 1/332 | 0.9991627 | 1 | 0 | 0 | 0.1437732 | 0.0001204 | RTEL1-TNFRSF6B |
| 1692 | ribonucleoside monophosphate catabolic process (GO:0009158) | 1/332 | 0.9991627 | 1 | 0 | 0 | 0.1437732 | 0.0001204 | RTEL1-TNFRSF6B |
| 1693 | purine nucleoside monophosphate catabolic process (GO:0009128) | 1/333 | 0.9991805 | 1 | 0 | 0 | 0.1433414 | 0.0001175 | RTEL1-TNFRSF6B |
| 1694 | nucleoside monophosphate catabolic process (GO:0009125) | 1/335 | 0.9992149 | 1 | 0 | 0 | 0.1424857 | 0.0001119 | RTEL1-TNFRSF6B |
| 1695 | regulation of lymphocyte activation (GO:0051249) | 1/344 | 0.9993527 | 1 | 0 | 0 | 0.1387578 | 0.0000898 | ZBTB16 |
| 1696 | response to other organism (GO:0051707) | 2/462 | 0.9994372 | 1 | 0 | 0 | 0.2066351 | 0.0001163 | IRAK3;APOB |
| 1697 | negative regulation of cellular component organization (GO:0051129) | 2/474 | 0.9995549 | 1 | 0 | 0 | 0.2014038 | 0.0000897 | IRAK3;THBS1 |
| 1698 | leukocyte activation (GO:0045321) | 1/373 | 0.9996522 | 1 | 0 | 0 | 0.1279697 | 0.0000445 | EDN2 |
| 1699 | ATP metabolic process (GO:0046034) | 1/377 | 0.9996807 | 1 | 0 | 0 | 0.1266119 | 0.0000404 | RTEL1-TNFRSF6B |
| 1700 | single-organism cellular localization (GO:1902580) | 2/496 | 0.9997107 | 1 | 0 | 0 | 0.1924706 | 0.0000557 | CPE;BHLHA15 |
| 1701 | purine ribonucleoside monophosphate metabolic process (GO:0009167) | 1/402 | 0.9998126 | 1 | 0 | 0 | 0.1187381 | 0.0000223 | RTEL1-TNFRSF6B |
| 1702 | purine nucleoside monophosphate metabolic process (GO:0009126) | 1/403 | 0.9998165 | 1 | 0 | 0 | 0.1184434 | 0.0000217 | RTEL1-TNFRSF6B |
| 1703 | mitotic cell cycle (GO:0000278) | 1/404 | 0.9998204 | 1 | 0 | 0 | 0.1181502 | 0.0000212 | NEK6 |
| 1704 | negative regulation of protein modification process (GO:0031400) | 1/407 | 0.9998314 | 1 | 0 | 0 | 0.1172794 | 0.0000198 | IRAK3 |
| 1705 | ribonucleoside monophosphate metabolic process (GO:0009161) | 1/416 | 0.9998607 | 1 | 0 | 0 | 0.1147421 | 0.0000160 | RTEL1-TNFRSF6B |
| 1706 | microtubule-based process (GO:0007017) | 1/437 | 0.9999103 | 1 | 0 | 0 | 0.1092281 | 0.0000098 | NEK6 |
| 1707 | posttranscriptional regulation of gene expression (GO:0010608) | 1/438 | 0.9999122 | 1 | 0 | 0 | 0.1089788 | 0.0000096 | THBS1 |
| 1708 | immune response-activating signal transduction (GO:0002757) | 1/440 | 0.9999158 | 1 | 0 | 0 | 0.1084834 | 0.0000091 | IRAK3 |
| 1709 | detection of chemical stimulus involved in sensory perception (GO:0050907) | 1/465 | 0.9999496 | 1 | 0 | 0 | 0.1026510 | 0.0000052 | AZGP1 |
| 1710 | chromatin modification (GO:0016568) | 1/475 | 0.9999588 | 1 | 0 | 0 | 0.1004899 | 0.0000041 | FOXA3 |
| 1711 | activation of immune response (GO:0002253) | 1/487 | 0.9999674 | 1 | 0 | 0 | 0.0980138 | 0.0000032 | IRAK3 |
| 1712 | detection of chemical stimulus (GO:0009593) | 1/499 | 0.9999741 | 1 | 0 | 0 | 0.0956567 | 0.0000025 | AZGP1 |
go_cellular %>%
knitr::kable(
format = "html", align = rep("c", ncol(go_cellular) + 1),
row.names = TRUE
) %>%
kableExtra::kable_styling() %>%
kableExtra::scroll_box(height = "300px")
| Term | Overlap | P.value | Adjusted.P.value | Old.P.value | Old.Adjusted.P.value | Odds.Ratio | Combined.Score | Genes | |
|---|---|---|---|---|---|---|---|---|---|
| 1 | fibril (GO:0043205) | 2/13 | 0.0293193 | 1 | 0 | 0 | 7.3434918 | 25.9189276 | FBN2;MUC5AC |
| 2 | extracellular space (GO:0005615) | 32/1120 | 0.0469779 | 1 | 0 | 0 | 1.3637913 | 4.1705816 | CSF3;PCDH15;STC1;PLAT;MSLN;CXCL2;THBS1;PTHLH;COMP;TPO;MUC1;C1QTNF1;LIPG;APOB;CTHRC1;SERPINB4;CCL24;LEFTY1;EDN2;AHSG;BMP8A;IL19;WNT16;F5;AZGP1;TCN1;PXDN;HMSD;LCN2;SSPO;TFF1;PKHD1L1 |
| 3 | Golgi lumen (GO:0005796) | 4/86 | 0.1065052 | 1 | 0 | 0 | 2.2201254 | 4.9721080 | MUC1;MUC3A;MUC5AC;MUC6 |
| 4 | troponin complex (GO:0005861) | 1/8 | 0.1558373 | 1 | 0 | 0 | 5.9665871 | 11.0915436 | TNNI3 |
| 5 | fibrinogen complex (GO:0005577) | 1/8 | 0.1558373 | 1 | 0 | 0 | 5.9665871 | 11.0915436 | THBS1 |
| 6 | asymmetric synapse (GO:0032279) | 1/8 | 0.1558373 | 1 | 0 | 0 | 5.9665871 | 11.0915436 | CHRM1 |
| 7 | microfibril (GO:0001527) | 1/9 | 0.1735296 | 1 | 0 | 0 | 5.3036330 | 9.2888214 | FBN2 |
| 8 | CatSper complex (GO:0036128) | 1/9 | 0.1735296 | 1 | 0 | 0 | 5.3036330 | 9.2888214 | CATSPERB |
| 9 | voltage-gated calcium channel complex (GO:0005891) | 2/38 | 0.1889323 | 1 | 0 | 0 | 2.5122472 | 4.1863248 | CATSPERB;CACNA1E |
| 10 | junctional sarcoplasmic reticulum membrane (GO:0014701) | 1/10 | 0.1908519 | 1 | 0 | 0 | 4.7732697 | 7.9057641 | JPH2 |
| 11 | vesicle lumen (GO:0031983) | 3/76 | 0.2132832 | 1 | 0 | 0 | 1.8841854 | 2.9113198 | APOB;THBS1;F5 |
| 12 | cytoplasmic membrane-bounded vesicle lumen (GO:0060205) | 3/76 | 0.2132832 | 1 | 0 | 0 | 1.8841854 | 2.9113198 | APOB;THBS1;F5 |
| 13 | endosome lumen (GO:0031904) | 1/12 | 0.2244175 | 1 | 0 | 0 | 3.9777247 | 5.9437046 | APOB |
| 14 | chylomicron (GO:0042627) | 1/13 | 0.2406756 | 1 | 0 | 0 | 3.6717459 | 5.2296866 | APOB |
| 15 | MHC class I protein complex (GO:0042612) | 1/13 | 0.2406756 | 1 | 0 | 0 | 3.6717459 | 5.2296866 | AZGP1 |
| 16 | platelet alpha granule (GO:0031091) | 1/13 | 0.2406756 | 1 | 0 | 0 | 3.6717459 | 5.2296866 | THBS1 |
| 17 | Golgi cisterna membrane (GO:0032580) | 1/14 | 0.2565938 | 1 | 0 | 0 | 3.4094783 | 4.6377803 | FUT6 |
| 18 | low-density lipoprotein particle (GO:0034362) | 1/14 | 0.2565938 | 1 | 0 | 0 | 3.4094783 | 4.6377803 | APOB |
| 19 | smooth endoplasmic reticulum (GO:0005790) | 1/14 | 0.2565938 | 1 | 0 | 0 | 3.4094783 | 4.6377803 | KCNN2 |
| 20 | platelet alpha granule lumen (GO:0031093) | 2/48 | 0.2663018 | 1 | 0 | 0 | 1.9888624 | 2.6315136 | THBS1;F5 |
| 21 | extracellular matrix part (GO:0044420) | 4/127 | 0.2761944 | 1 | 0 | 0 | 1.5033920 | 1.9343398 | FBN2;ENTPD2;NID2;MUC5AC |
| 22 | basal lamina (GO:0005605) | 1/16 | 0.2874383 | 1 | 0 | 0 | 2.9832936 | 3.7194122 | ENTPD2 |
| 23 | endocytic vesicle lumen (GO:0071682) | 1/16 | 0.2874383 | 1 | 0 | 0 | 2.9832936 | 3.7194122 | APOB |
| 24 | extracellular matrix (GO:0031012) | 9/348 | 0.3076000 | 1 | 0 | 0 | 1.2344663 | 1.4553804 | COMP;FBN2;PXDN;CHAD;PLAT;WNT16;NID2;THBS1;CTHRC1 |
| 25 | neuronal postsynaptic density (GO:0097481) | 1/18 | 0.3170060 | 1 | 0 | 0 | 2.6518165 | 3.0464985 | NTRK2 |
| 26 | mast cell granule (GO:0042629) | 1/18 | 0.3170060 | 1 | 0 | 0 | 2.6518165 | 3.0464985 | ADORA3 |
| 27 | desmosome (GO:0030057) | 1/19 | 0.3313276 | 1 | 0 | 0 | 2.5122472 | 2.7751481 | CDSN |
| 28 | excitatory synapse (GO:0060076) | 1/19 | 0.3313276 | 1 | 0 | 0 | 2.5122472 | 2.7751481 | NTRK2 |
| 29 | stereocilium (GO:0032420) | 1/19 | 0.3313276 | 1 | 0 | 0 | 2.5122472 | 2.7751481 | PCDH15 |
| 30 | calcium channel complex (GO:0034704) | 2/57 | 0.3360828 | 1 | 0 | 0 | 1.6748315 | 1.8262323 | CATSPERB;CACNA1E |
| 31 | very-low-density lipoprotein particle (GO:0034361) | 1/20 | 0.3453496 | 1 | 0 | 0 | 2.3866348 | 2.5374656 | APOB |
| 32 | triglyceride-rich lipoprotein particle (GO:0034385) | 1/20 | 0.3453496 | 1 | 0 | 0 | 2.3866348 | 2.5374656 | APOB |
| 33 | costamere (GO:0043034) | 1/21 | 0.3590782 | 1 | 0 | 0 | 2.2729856 | 2.3280260 | FLNC |
| 34 | secretory granule lumen (GO:0034774) | 2/62 | 0.3740573 | 1 | 0 | 0 | 1.5397644 | 1.5141217 | THBS1;F5 |
| 35 | proteinaceous extracellular matrix (GO:0005578) | 6/239 | 0.3852649 | 1 | 0 | 0 | 1.1983104 | 1.1429775 | COMP;FBN2;PXDN;CHAD;WNT16;CTHRC1 |
| 36 | cornified envelope (GO:0001533) | 1/23 | 0.3856798 | 1 | 0 | 0 | 2.0753346 | 1.9772706 | CDSN |
| 37 | sarcoplasmic reticulum membrane (GO:0033017) | 1/23 | 0.3856798 | 1 | 0 | 0 | 2.0753346 | 1.9772706 | JPH2 |
| 38 | synapse (GO:0045202) | 6/243 | 0.4002119 | 1 | 0 | 0 | 1.1785851 | 1.0793025 | NTRK2;CHRM1;PCDH15;PLAT;CDH15;ADRA2A |
| 39 | presynaptic active zone (GO:0048786) | 1/25 | 0.4111798 | 1 | 0 | 0 | 1.9093079 | 1.6968492 | NTRK2 |
| 40 | myosin II complex (GO:0016460) | 1/25 | 0.4111798 | 1 | 0 | 0 | 1.9093079 | 1.6968492 | SHROOM1 |
| 41 | dendritic spine (GO:0043197) | 2/71 | 0.4399794 | 1 | 0 | 0 | 1.3445830 | 1.1039396 | NTRK2;KCNN2 |
| 42 | MHC protein complex (GO:0042611) | 1/29 | 0.4590552 | 1 | 0 | 0 | 1.6459551 | 1.2815157 | AZGP1 |
| 43 | neuron spine (GO:0044309) | 2/74 | 0.4611076 | 1 | 0 | 0 | 1.2900729 | 0.9986763 | NTRK2;KCNN2 |
| 44 | contractile fiber part (GO:0044449) | 4/167 | 0.4646495 | 1 | 0 | 0 | 1.1432981 | 0.8763060 | JPH2;KCNN2;TNNI3;FLNC |
| 45 | clathrin-coated endocytic vesicle membrane (GO:0030669) | 1/31 | 0.4815161 | 1 | 0 | 0 | 1.5397644 | 1.1252839 | APOB |
| 46 | integrin complex (GO:0008305) | 1/31 | 0.4815161 | 1 | 0 | 0 | 1.5397644 | 1.1252839 | ITGA10 |
| 47 | sarcomere (GO:0030017) | 1/31 | 0.4815161 | 1 | 0 | 0 | 1.5397644 | 1.1252839 | TNNI3 |
| 48 | protein complex involved in cell adhesion (GO:0098636) | 1/31 | 0.4815161 | 1 | 0 | 0 | 1.5397644 | 1.1252839 | ITGA10 |
| 49 | photoreceptor outer segment (GO:0001750) | 1/34 | 0.5134749 | 1 | 0 | 0 | 1.4039028 | 0.9357774 | PCDH15 |
| 50 | axon terminus (GO:0043679) | 1/34 | 0.5134749 | 1 | 0 | 0 | 1.4039028 | 0.9357774 | CHRM1 |
| 51 | SNARE complex (GO:0031201) | 1/35 | 0.5236849 | 1 | 0 | 0 | 1.3637913 | 0.8821891 | DOC2B |
| 52 | T-tubule (GO:0030315) | 1/36 | 0.5336812 | 1 | 0 | 0 | 1.3259082 | 0.8326130 | KCNN2 |
| 53 | synaptic vesicle (GO:0008021) | 2/86 | 0.5406975 | 1 | 0 | 0 | 1.1100627 | 0.6825724 | DOC2B;SYT8 |
| 54 | Z disc (GO:0030018) | 2/87 | 0.5469535 | 1 | 0 | 0 | 1.0973034 | 0.6621035 | JPH2;KCNN2 |
| 55 | plasma lipoprotein particle (GO:0034358) | 1/38 | 0.5530502 | 1 | 0 | 0 | 1.2561236 | 0.7440102 | APOB |
| 56 | basolateral plasma membrane (GO:0016323) | 3/138 | 0.5548702 | 1 | 0 | 0 | 1.0376673 | 0.6112080 | CEACAM5;SLC13A5;ADRA2A |
| 57 | terminal bouton (GO:0043195) | 1/39 | 0.5624316 | 1 | 0 | 0 | 1.2239153 | 0.7043459 | NTRK2 |
| 58 | collagen trimer (GO:0005581) | 2/91 | 0.5713775 | 1 | 0 | 0 | 1.0490703 | 0.5871700 | C1QTNF1;CTHRC1 |
| 59 | protein-lipid complex (GO:0032994) | 1/40 | 0.5716165 | 1 | 0 | 0 | 1.1933174 | 0.6674069 | APOB |
| 60 | sarcoplasmic reticulum (GO:0016529) | 1/40 | 0.5716165 | 1 | 0 | 0 | 1.1933174 | 0.6674069 | THBS1 |
| 61 | presynaptic membrane (GO:0042734) | 1/44 | 0.6064726 | 1 | 0 | 0 | 1.0848340 | 0.5425209 | GRM8 |
| 62 | phagocytic vesicle (GO:0045335) | 1/44 | 0.6064726 | 1 | 0 | 0 | 1.0848340 | 0.5425209 | RAB43 |
| 63 | neuron projection terminus (GO:0044306) | 1/44 | 0.6064726 | 1 | 0 | 0 | 1.0848340 | 0.5425209 | CHRM1 |
| 64 | postsynaptic density (GO:0014069) | 2/98 | 0.6117869 | 1 | 0 | 0 | 0.9741367 | 0.4786628 | NTRK2;CHRM1 |
| 65 | neuromuscular junction (GO:0031594) | 1/47 | 0.6307446 | 1 | 0 | 0 | 1.0155893 | 0.4680387 | CDH15 |
| 66 | clathrin-coated vesicle membrane (GO:0030665) | 1/48 | 0.6384987 | 1 | 0 | 0 | 0.9944312 | 0.4461373 | APOB |
| 67 | chloride channel complex (GO:0034707) | 1/50 | 0.6535229 | 1 | 0 | 0 | 0.9546539 | 0.4060885 | ANO1 |
| 68 | axon (GO:0030424) | 3/161 | 0.6589222 | 1 | 0 | 0 | 0.8894291 | 0.3710251 | OMP;SLC6A1;CYP17A1 |
| 69 | secretory granule membrane (GO:0030667) | 1/54 | 0.6817282 | 1 | 0 | 0 | 0.8839388 | 0.3386584 | CPE |
| 70 | plasma membrane raft (GO:0044853) | 1/58 | 0.7076424 | 1 | 0 | 0 | 0.8229775 | 0.2845991 | CDH15 |
| 71 | caveola (GO:0005901) | 1/58 | 0.7076424 | 1 | 0 | 0 | 0.8229775 | 0.2845991 | CDH15 |
| 72 | recycling endosome (GO:0055037) | 1/60 | 0.7197990 | 1 | 0 | 0 | 0.7955449 | 0.2615619 | REP15 |
| 73 | plasma membrane region (GO:0098590) | 7/395 | 0.7243853 | 1 | 0 | 0 | 0.8458959 | 0.2727438 | ANO1;MUC1;CEACAM5;STC1;CDH15;SLC13A5;ADRA2A |
| 74 | microvillus (GO:0005902) | 1/61 | 0.7256868 | 1 | 0 | 0 | 0.7825032 | 0.2508993 | PCDH15 |
| 75 | sarcolemma (GO:0042383) | 1/63 | 0.7370948 | 1 | 0 | 0 | 0.7576619 | 0.2311162 | FLNC |
| 76 | myosin complex (GO:0016459) | 1/64 | 0.7426200 | 1 | 0 | 0 | 0.7458234 | 0.2219352 | SHROOM1 |
| 77 | nuclear matrix (GO:0016363) | 1/64 | 0.7426200 | 1 | 0 | 0 | 0.7458234 | 0.2219352 | FIGN |
| 78 | extracellular region (GO:0005576) | 30/1585 | 0.7466204 | 1 | 0 | 0 | 0.9034580 | 0.2639889 | FBN2;ADAMDEC1;CSF3;PLAT;NID2;CXCL2;THBS1;ABO;PTHLH;COMP;LIPG;CREG2;APOB;MUC6;SERPINB4;CGREF1;EDN2;AHSG;IL1R2;REG4;IL19;WNT16;MUC3A;F5;AZGP1;TCN1;ADM2;BPIFB6;LCN2;KCP |
| 79 | coated vesicle membrane (GO:0030662) | 1/66 | 0.7533254 | 1 | 0 | 0 | 0.7232227 | 0.2048586 | APOB |
| 80 | nonmotile primary cilium (GO:0031513) | 1/67 | 0.7585103 | 1 | 0 | 0 | 0.7124283 | 0.1969144 | PCDH15 |
| 81 | PML body (GO:0016605) | 1/68 | 0.7635865 | 1 | 0 | 0 | 0.7019514 | 0.1893366 | ZBTB16 |
| 82 | axon part (GO:0033267) | 2/133 | 0.7708418 | 1 | 0 | 0 | 0.7177849 | 0.1868194 | NTRK2;CHRM1 |
| 83 | transcriptional repressor complex (GO:0017053) | 1/70 | 0.7734217 | 1 | 0 | 0 | 0.6818957 | 0.1752000 | ZBTB16 |
| 84 | apical plasma membrane (GO:0016324) | 3/201 | 0.7957327 | 1 | 0 | 0 | 0.7124283 | 0.1627841 | ANO1;MUC1;STC1 |
| 85 | basement membrane (GO:0005604) | 1/77 | 0.8047394 | 1 | 0 | 0 | 0.6199052 | 0.1346662 | NID2 |
| 86 | cell surface (GO:0009986) | 7/437 | 0.8128618 | 1 | 0 | 0 | 0.7645970 | 0.1584201 | NTRK2;MUC1;PLAT;SLC6A1;MSLN;NID2;THBS1 |
| 87 | cation channel complex (GO:0034703) | 2/147 | 0.8166169 | 1 | 0 | 0 | 0.6494244 | 0.1315638 | CATSPERB;CACNA1E |
| 88 | neuronal cell body (GO:0043025) | 4/270 | 0.8202560 | 1 | 0 | 0 | 0.7071511 | 0.1401141 | NTRK2;OMP;KCNN2;CYP17A1 |
| 89 | receptor complex (GO:0043235) | 4/272 | 0.8246228 | 1 | 0 | 0 | 0.7019514 | 0.1353567 | NTRK2;GPR37;ITGA10;ADRA2A |
| 90 | anchored component of membrane (GO:0031225) | 2/150 | 0.8252959 | 1 | 0 | 0 | 0.6364360 | 0.1222042 | CEACAM5;MSLN |
| 91 | nuclear speck (GO:0016607) | 1/84 | 0.8317373 | 1 | 0 | 0 | 0.5682464 | 0.1046930 | ZBTB16 |
| 92 | apical part of cell (GO:0045177) | 1/87 | 0.8421357 | 1 | 0 | 0 | 0.5486517 | 0.0942661 | PLAT |
| 93 | synaptic membrane (GO:0097060) | 3/228 | 0.8595501 | 1 | 0 | 0 | 0.6280618 | 0.0950547 | NTRK2;CHRM1;GRM8 |
| 94 | endocytic vesicle membrane (GO:0030666) | 1/94 | 0.8639732 | 1 | 0 | 0 | 0.5077946 | 0.0742465 | APOB |
| 95 | endocytic vesicle (GO:0030139) | 1/96 | 0.8696394 | 1 | 0 | 0 | 0.4972156 | 0.0694494 | RAB43 |
| 96 | primary cilium (GO:0072372) | 1/99 | 0.8777003 | 1 | 0 | 0 | 0.4821485 | 0.0628963 | PCDH15 |
| 97 | growth cone (GO:0030426) | 1/99 | 0.8777003 | 1 | 0 | 0 | 0.4821485 | 0.0628963 | NTRK2 |
| 98 | endosome membrane (GO:0010008) | 2/175 | 0.8843850 | 1 | 0 | 0 | 0.5455165 | 0.0670237 | REP15;APOB |
| 99 | site of polarized growth (GO:0030427) | 1/102 | 0.8852638 | 1 | 0 | 0 | 0.4679676 | 0.0570310 | NTRK2 |
| 100 | secretory granule (GO:0030141) | 2/176 | 0.8863125 | 1 | 0 | 0 | 0.5424170 | 0.0654620 | PLAT;THBS1 |
| 101 | nuclear chromatin (GO:0000790) | 2/177 | 0.8882102 | 1 | 0 | 0 | 0.5393525 | 0.0639385 | MUC1;PAX6 |
| 102 | cell body (GO:0044297) | 4/315 | 0.8991009 | 1 | 0 | 0 | 0.6061295 | 0.0644679 | NTRK2;OMP;KCNN2;CYP17A1 |
| 103 | peroxisome (GO:0005777) | 1/109 | 0.9011464 | 1 | 0 | 0 | 0.4379147 | 0.0455814 | SERHL2 |
| 104 | ion channel complex (GO:0034702) | 3/258 | 0.9093509 | 1 | 0 | 0 | 0.5550314 | 0.0527414 | ANO1;CATSPERB;CACNA1E |
| 105 | endoplasmic reticulum membrane (GO:0005789) | 6/449 | 0.9116705 | 1 | 0 | 0 | 0.6378534 | 0.0589866 | JPH2;PTGS2;APOB;CYP3A5;FKBP5;CYP17A1 |
| 106 | external side of plasma membrane (GO:0009897) | 2/191 | 0.9118692 | 1 | 0 | 0 | 0.4998188 | 0.0461126 | ANO1;THBS1 |
| 107 | extrinsic component of membrane (GO:0019898) | 1/115 | 0.9130018 | 1 | 0 | 0 | 0.4150669 | 0.0377783 | ALOX15B |
| 108 | actin cytoskeleton (GO:0015629) | 2/193 | 0.9148392 | 1 | 0 | 0 | 0.4946393 | 0.0440263 | APOB;MYLK3 |
| 109 | postsynaptic membrane (GO:0045211) | 2/195 | 0.9177153 | 1 | 0 | 0 | 0.4895661 | 0.0420381 | NTRK2;CHRM1 |
| 110 | synapse part (GO:0044456) | 5/395 | 0.9193926 | 1 | 0 | 0 | 0.6042114 | 0.0507791 | NTRK2;CHRM1;GRM8;DOC2B;SYT8 |
| 111 | endosomal part (GO:0044440) | 2/200 | 0.9245113 | 1 | 0 | 0 | 0.4773270 | 0.0374654 | REP15;APOB |
| 112 | microbody (GO:0042579) | 1/123 | 0.9266318 | 1 | 0 | 0 | 0.3880707 | 0.0295706 | SERHL2 |
| 113 | transmembrane transporter complex (GO:1902495) | 3/286 | 0.9407943 | 1 | 0 | 0 | 0.5006926 | 0.0305576 | ANO1;CATSPERB;CACNA1E |
| 114 | transporter complex (GO:1990351) | 3/291 | 0.9452165 | 1 | 0 | 0 | 0.4920897 | 0.0277250 | ANO1;CATSPERB;CACNA1E |
| 115 | cytoplasmic membrane-bounded vesicle (GO:0016023) | 6/492 | 0.9475602 | 1 | 0 | 0 | 0.5821061 | 0.0313550 | RAB43;SERHL2;PLAT;DOC2B;SYT8;THBS1 |
| 116 | cytoplasmic vesicle part (GO:0044433) | 4/363 | 0.9480627 | 1 | 0 | 0 | 0.5259801 | 0.0280530 | CPE;APOB;THBS1;F5 |
| 117 | early endosome (GO:0005769) | 1/141 | 0.9500087 | 1 | 0 | 0 | 0.3385298 | 0.0173612 | APOB |
| 118 | cytoplasmic vesicle membrane (GO:0030659) | 2/229 | 0.9545841 | 1 | 0 | 0 | 0.4168794 | 0.0193764 | CPE;APOB |
| 119 | side of membrane (GO:0098552) | 2/235 | 0.9591806 | 1 | 0 | 0 | 0.4062357 | 0.0169302 | ANO1;THBS1 |
| 120 | endoplasmic reticulum lumen (GO:0005788) | 1/154 | 0.9621149 | 1 | 0 | 0 | 0.3099526 | 0.0119708 | APOB |
| 121 | cilium (GO:0005929) | 2/243 | 0.9646208 | 1 | 0 | 0 | 0.3928617 | 0.0141510 | CATSPERB;PCDH15 |
| 122 | blood microparticle (GO:0072562) | 1/161 | 0.9673719 | 1 | 0 | 0 | 0.2964764 | 0.0098348 | AHSG |
| 123 | vesicle membrane (GO:0012506) | 2/249 | 0.9682370 | 1 | 0 | 0 | 0.3833952 | 0.0123754 | CPE;APOB |
| 124 | lysosome (GO:0005764) | 2/261 | 0.9744325 | 1 | 0 | 0 | 0.3657678 | 0.0094734 | ADORA3;PRSS16 |
| 125 | lytic vacuole (GO:0000323) | 2/261 | 0.9744325 | 1 | 0 | 0 | 0.3657678 | 0.0094734 | ADORA3;PRSS16 |
| 126 | Golgi apparatus (GO:0005794) | 11/865 | 0.9750118 | 1 | 0 | 0 | 0.6070054 | 0.0153607 | RAB43;GOLGA7B;FUT6;GOLGA6B;CREG2;CPE;MSLN;APOB;ABO;JAKMIP3;PTHLH |
| 127 | ubiquitin ligase complex (GO:0000151) | 1/183 | 0.9796038 | 1 | 0 | 0 | 0.2608344 | 0.0053750 | GPR37 |
| 128 | integral component of plasma membrane (GO:0005887) | 14/1066 | 0.9798480 | 1 | 0 | 0 | 0.6268834 | 0.0127620 | NTRK2;SLC26A2;GPR37;CHRM1;SLC6A1;PTPRH;ADRA2A;TPO;MUC1;C1QTNF1;ADORA3;CEACAM5;SLCO1B3;GRM8 |
| 129 | microtubule (GO:0005874) | 3/360 | 0.9819795 | 1 | 0 | 0 | 0.3977725 | 0.0072334 | NEK6;FIGN;SHROOM1 |
| 130 | chromatin (GO:0000785) | 2/289 | 0.9846866 | 1 | 0 | 0 | 0.3303301 | 0.0050976 | MUC1;PAX6 |
| 131 | vacuole (GO:0005773) | 2/293 | 0.9857773 | 1 | 0 | 0 | 0.3258205 | 0.0046673 | ADORA3;PRSS16 |
| 132 | membrane raft (GO:0045121) | 1/200 | 0.9858182 | 1 | 0 | 0 | 0.2386635 | 0.0034089 | CDH15 |
| 133 | mitochondrial matrix (GO:0005759) | 1/208 | 0.9880485 | 1 | 0 | 0 | 0.2294841 | 0.0027592 | PYCR1 |
| 134 | nuclear body (GO:0016604) | 1/210 | 0.9885491 | 1 | 0 | 0 | 0.2272986 | 0.0026178 | ZBTB16 |
| 135 | Golgi membrane (GO:0000139) | 2/308 | 0.9892340 | 1 | 0 | 0 | 0.3099526 | 0.0033550 | FUT6;B3GNT6 |
| 136 | nuclear chromosome part (GO:0044454) | 2/327 | 0.9924554 | 1 | 0 | 0 | 0.2919431 | 0.0022109 | MUC1;PAX6 |
| 137 | dendrite (GO:0030425) | 1/236 | 0.9934367 | 1 | 0 | 0 | 0.2022572 | 0.0013318 | CHRM1 |
| 138 | mitochondrial inner membrane (GO:0005743) | 2/341 | 0.9942053 | 1 | 0 | 0 | 0.2799572 | 0.0016270 | SLC25A48;SLC25A18 |
| 139 | organelle inner membrane (GO:0019866) | 2/360 | 0.9959591 | 1 | 0 | 0 | 0.2651816 | 0.0010737 | SLC25A48;SLC25A18 |
| 140 | anchoring junction (GO:0070161) | 2/419 | 0.9986999 | 1 | 0 | 0 | 0.2278410 | 0.0002964 | CDSN;FLNC |
| 141 | cell-cell junction (GO:0005911) | 1/335 | 0.9992149 | 1 | 0 | 0 | 0.1424857 | 0.0001119 | CDSN |
| 142 | mitochondrial membrane (GO:0031966) | 2/457 | 0.9993794 | 1 | 0 | 0 | 0.2088958 | 0.0001297 | SLC25A48;SLC25A18 |
| 143 | focal adhesion (GO:0005925) | 1/352 | 0.9994547 | 1 | 0 | 0 | 0.1356043 | 0.0000740 | FLNC |
| 144 | cell-substrate adherens junction (GO:0005924) | 1/358 | 0.9995205 | 1 | 0 | 0 | 0.1333316 | 0.0000639 | FLNC |
| 145 | cell-substrate junction (GO:0030055) | 1/362 | 0.9995599 | 1 | 0 | 0 | 0.1318583 | 0.0000580 | FLNC |
| 146 | adherens junction (GO:0005912) | 1/405 | 0.9998241 | 1 | 0 | 0 | 0.1178585 | 0.0000207 | FLNC |
| 147 | perinuclear region of cytoplasm (GO:0048471) | 1/411 | 0.9998451 | 1 | 0 | 0 | 0.1161379 | 0.0000180 | REP15 |
| 148 | intracellular (GO:0005622) | 4/730 | 0.9998728 | 1 | 0 | 0 | 0.2615490 | 0.0000333 | ARHGAP40;ANO7;ALOX15B;NKX3-1 |
| 149 | extracellular vesicular exosome (GO:0070062) | 31/2717 | 0.9999737 | 1 | 0 | 0 | 0.5446130 | 0.0000143 | SLC26A2;CPNE4;SEMA3B;PCDH15;PLAT;ALDH1L2;NID2;THBS1;RAB43;COMP;FUT6;SULT1C2;MUC1;CUX2;APOB;SERPINB4;ENTPD2;CDSN;AHSG;ALOX15B;MUC5AC;ANO1;AZGP1;BPIFB2;CEACAM5;PXDN;LCN2;CPE;CDH15;FKBP5;AQP7P3 |
| 150 | cytosol (GO:0005829) | 12/2529 | 0.9999945 | 1 | 0 | 0 | 0.2264897 | 0.0000012 | SULT1C2;NTRK2;ARHGAP40;ZBTB16;NEK6;HKDC1;TNNI3;FLNC;PKHD1L1;APOB;ALOX15B;MYLK3 |
| 151 | nucleolus (GO:0005730) | 3/1653 | 0.9999951 | 1 | 0 | 0 | 0.0866292 | 0.0000004 | PHACTR3;PTHLH;FKBP5 |
| 152 | mitochondrion (GO:0005739) | 5/1269 | 0.9999954 | 1 | 0 | 0 | 0.1880721 | 0.0000009 | TPO;PYCR1;SERHL2;ALDH1L2;CYP17A1 |
go_molecular %>%
knitr::kable(
format = "html", align = rep("c", ncol(go_molecular) + 1),
row.names = TRUE
) %>%
kableExtra::kable_styling() %>%
kableExtra::scroll_box(height = "300px")
| Term | Overlap | P.value | Adjusted.P.value | Old.P.value | Old.Adjusted.P.value | Odds.Ratio | Combined.Score | Genes | |
|---|---|---|---|---|---|---|---|---|---|
| 1 | extracellular matrix structural constituent (GO:0005201) | 6/68 | 0.0029878 | 1 | 0 | 0 | 4.2117085 | 24.4835709 | COMP;FBN2;PXDN;MUC3A;MUC5AC;MUC6 |
| 2 | collagen binding (GO:0005518) | 5/62 | 0.0095910 | 1 | 0 | 0 | 3.8494110 | 17.8879540 | COMP;C1QTNF1;ITGA10;NID2;THBS1 |
| 3 | intracellular calcium activated chloride channel activity (GO:0005229) | 2/12 | 0.0251521 | 1 | 0 | 0 | 7.9554495 | 29.2984249 | ANO1;ANO7 |
| 4 | nucleoside-diphosphatase activity (GO:0017110) | 2/13 | 0.0293193 | 1 | 0 | 0 | 7.3434918 | 25.9189276 | ENTPD2;ENTPD8 |
| 5 | ion gated channel activity (GO:0022839) | 3/40 | 0.0509843 | 1 | 0 | 0 | 3.5799523 | 10.6547898 | ANO1;KCNN2;ANO7 |
| 6 | peroxidase activity (GO:0004601) | 3/42 | 0.0574810 | 1 | 0 | 0 | 3.4094783 | 9.7384978 | TPO;PXDN;PTGS2 |
| 7 | oxidoreductase activity, acting on peroxide as acceptor (GO:0016684) | 3/42 | 0.0574810 | 1 | 0 | 0 | 3.4094783 | 9.7384978 | TPO;PXDN;PTGS2 |
| 8 | oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor (GO:0016646) | 2/19 | 0.0592174 | 1 | 0 | 0 | 5.0244944 | 14.2019371 | PYCR1;ALDH1L2 |
| 9 | phosphatidylserine binding (GO:0001786) | 2/23 | 0.0829959 | 1 | 0 | 0 | 4.1506693 | 10.3308677 | JPH2;THBS1 |
| 10 | tetrapyrrole binding (GO:0046906) | 6/146 | 0.0870458 | 1 | 0 | 0 | 1.9616177 | 4.7889376 | TPO;TCN1;PXDN;PTGS2;CYP3A5;CYP17A1 |
| 11 | oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen (GO:0016702) | 2/25 | 0.0958000 | 1 | 0 | 0 | 3.8186158 | 8.9565341 | PTGS2;ALOX15B |
| 12 | oxidoreductase activity, acting on single donors with incorporation of molecular oxygen (GO:0016701) | 2/26 | 0.1023997 | 1 | 0 | 0 | 3.6717459 | 8.3674372 | PTGS2;ALOX15B |
| 13 | calmodulin-dependent protein kinase activity (GO:0004683) | 2/26 | 0.1023997 | 1 | 0 | 0 | 3.6717459 | 8.3674372 | PNCK;MYLK3 |
| 14 | proteoglycan binding (GO:0043394) | 2/27 | 0.1091201 | 1 | 0 | 0 | 3.5357553 | 7.8327816 | COMP;THBS1 |
| 15 | oxidoreductase activity, acting on the CH-NH group of donors (GO:0016645) | 2/28 | 0.1159532 | 1 | 0 | 0 | 3.4094783 | 7.3459547 | PYCR1;ALDH1L2 |
| 16 | organic acid:sodium symporter activity (GO:0005343) | 2/28 | 0.1159532 | 1 | 0 | 0 | 3.4094783 | 7.3459547 | SLC6A1;SLC13A5 |
| 17 | calcium activated cation channel activity (GO:0005227) | 2/29 | 0.1228915 | 1 | 0 | 0 | 3.2919101 | 6.9013369 | ANO1;KCNN2 |
| 18 | GPI anchor binding (GO:0034235) | 1/8 | 0.1558373 | 1 | 0 | 0 | 5.9665871 | 11.0915436 | CEACAM5 |
| 19 | alpha-(1->3)-fucosyltransferase activity (GO:0046920) | 1/8 | 0.1558373 | 1 | 0 | 0 | 5.9665871 | 11.0915436 | FUT6 |
| 20 | phospholipid scramblase activity (GO:0017128) | 1/8 | 0.1558373 | 1 | 0 | 0 | 5.9665871 | 11.0915436 | ANO7 |
| 21 | AT DNA binding (GO:0003680) | 1/8 | 0.1558373 | 1 | 0 | 0 | 5.9665871 | 11.0915436 | PAX6 |
| 22 | transcription corepressor binding (GO:0001222) | 1/8 | 0.1558373 | 1 | 0 | 0 | 5.9665871 | 11.0915436 | SIX3 |
| 23 | phosphatidylinositol-5-phosphate binding (GO:0010314) | 1/8 | 0.1558373 | 1 | 0 | 0 | 5.9665871 | 11.0915436 | JPH2 |
| 24 | hydroxymethyl-, formyl- and related transferase activity (GO:0016742) | 1/8 | 0.1558373 | 1 | 0 | 0 | 5.9665871 | 11.0915436 | ALDH1L2 |
| 25 | ion channel inhibitor activity (GO:0008200) | 2/34 | 0.1589105 | 1 | 0 | 0 | 2.8078057 | 5.1647173 | ANKRD36C;TNNI3 |
| 26 | galactosyltransferase activity (GO:0008378) | 2/34 | 0.1589105 | 1 | 0 | 0 | 2.8078057 | 5.1647173 | B3GNT6;ABO |
| 27 | heme binding (GO:0020037) | 5/137 | 0.1608405 | 1 | 0 | 0 | 1.7420692 | 3.1833567 | TPO;PXDN;PTGS2;CYP3A5;CYP17A1 |
| 28 | channel inhibitor activity (GO:0016248) | 2/35 | 0.1663335 | 1 | 0 | 0 | 2.7275827 | 4.8926297 | ANKRD36C;TNNI3 |
| 29 | heparin binding (GO:0008201) | 5/140 | 0.1711062 | 1 | 0 | 0 | 1.7047392 | 3.0096678 | COMP;REG4;LIPG;APOB;THBS1 |
| 30 | neurotrophin binding (GO:0043121) | 1/9 | 0.1735296 | 1 | 0 | 0 | 5.3036330 | 9.2888214 | NTRK2 |
| 31 | aldehyde-lyase activity (GO:0016832) | 1/9 | 0.1735296 | 1 | 0 | 0 | 5.3036330 | 9.2888214 | CYP17A1 |
| 32 | protein binding involved in cell adhesion (GO:0098631) | 1/9 | 0.1735296 | 1 | 0 | 0 | 5.3036330 | 9.2888214 | ITGA10 |
| 33 | adrenergic receptor activity (GO:0004935) | 1/9 | 0.1735296 | 1 | 0 | 0 | 5.3036330 | 9.2888214 | ADRA2A |
| 34 | cobalamin binding (GO:0031419) | 1/9 | 0.1735296 | 1 | 0 | 0 | 5.3036330 | 9.2888214 | TCN1 |
| 35 | frizzled binding (GO:0005109) | 2/36 | 0.1738152 | 1 | 0 | 0 | 2.6518165 | 4.6400487 | WNT16;CTHRC1 |
| 36 | antioxidant activity (GO:0016209) | 3/70 | 0.1811279 | 1 | 0 | 0 | 2.0456870 | 3.4951626 | TPO;PXDN;PTGS2 |
| 37 | oxygen binding (GO:0019825) | 2/37 | 0.1813500 | 1 | 0 | 0 | 2.5801458 | 4.4051511 | CYP3A5;CYP17A1 |
| 38 | transcription cofactor binding (GO:0001221) | 1/10 | 0.1908519 | 1 | 0 | 0 | 4.7732697 | 7.9057641 | SIX3 |
| 39 | sodium:amino acid symporter activity (GO:0005283) | 1/10 | 0.1908519 | 1 | 0 | 0 | 4.7732697 | 7.9057641 | SLC6A1 |
| 40 | GTP-Rho binding (GO:0017049) | 1/10 | 0.1908519 | 1 | 0 | 0 | 4.7732697 | 7.9057641 | CDC42EP5 |
| 41 | sodium:dicarboxylate symporter activity (GO:0017153) | 1/10 | 0.1908519 | 1 | 0 | 0 | 4.7732697 | 7.9057641 | SLC13A5 |
| 42 | semaphorin receptor binding (GO:0030215) | 1/10 | 0.1908519 | 1 | 0 | 0 | 4.7732697 | 7.9057641 | SEMA6B |
| 43 | RNA polymerase II core promoter sequence-specific DNA binding transcription factor activity (GO:0000983) | 1/10 | 0.1908519 | 1 | 0 | 0 | 4.7732697 | 7.9057641 | NKX3-1 |
| 44 | high voltage-gated calcium channel activity (GO:0008331) | 1/10 | 0.1908519 | 1 | 0 | 0 | 4.7732697 | 7.9057641 | CACNA1E |
| 45 | calcium channel inhibitor activity (GO:0019855) | 1/11 | 0.2078120 | 1 | 0 | 0 | 4.3393361 | 6.8176239 | TNNI3 |
| 46 | receptor antagonist activity (GO:0048019) | 1/11 | 0.2078120 | 1 | 0 | 0 | 4.3393361 | 6.8176239 | PXDN |
| 47 | cholesterol transporter activity (GO:0017127) | 1/11 | 0.2078120 | 1 | 0 | 0 | 4.3393361 | 6.8176239 | APOB |
| 48 | secondary active sulfate transmembrane transporter activity (GO:0008271) | 1/11 | 0.2078120 | 1 | 0 | 0 | 4.3393361 | 6.8176239 | SLC26A2 |
| 49 | phospholipid transporter activity (GO:0005548) | 2/41 | 0.2119125 | 1 | 0 | 0 | 2.3284242 | 3.6127403 | ATP10B;ANO7 |
| 50 | G-protein coupled amine receptor activity (GO:0008227) | 2/41 | 0.2119125 | 1 | 0 | 0 | 2.3284242 | 3.6127403 | CHRM1;ADRA2A |
| 51 | thioesterase binding (GO:0031996) | 1/12 | 0.2244175 | 1 | 0 | 0 | 3.9777247 | 5.9437046 | ADRA2A |
| 52 | cation:amino acid symporter activity (GO:0005416) | 1/12 | 0.2244175 | 1 | 0 | 0 | 3.9777247 | 5.9437046 | SLC6A1 |
| 53 | co-SMAD binding (GO:0070410) | 1/12 | 0.2244175 | 1 | 0 | 0 | 3.9777247 | 5.9437046 | PAX6 |
| 54 | sterol transporter activity (GO:0015248) | 1/12 | 0.2244175 | 1 | 0 | 0 | 3.9777247 | 5.9437046 | APOB |
| 55 | receptor inhibitor activity (GO:0030547) | 1/12 | 0.2244175 | 1 | 0 | 0 | 3.9777247 | 5.9437046 | PXDN |
| 56 | low-density lipoprotein particle receptor binding (GO:0050750) | 1/13 | 0.2406756 | 1 | 0 | 0 | 3.6717459 | 5.2296866 | APOB |
| 57 | phosphatidylinositol-3,5-bisphosphate binding (GO:0080025) | 1/13 | 0.2406756 | 1 | 0 | 0 | 3.6717459 | 5.2296866 | JPH2 |
| 58 | neurexin family protein binding (GO:0042043) | 1/13 | 0.2406756 | 1 | 0 | 0 | 3.6717459 | 5.2296866 | CPE |
| 59 | glycoprotein binding (GO:0001948) | 3/81 | 0.2409331 | 1 | 0 | 0 | 1.7678777 | 2.5161070 | COMP;AZGP1;THBS1 |
| 60 | hormone activity (GO:0005179) | 4/122 | 0.2530952 | 1 | 0 | 0 | 1.5650065 | 2.1503028 | EDN2;ADM2;STC1;PTHLH |
| 61 | catecholamine binding (GO:1901338) | 1/14 | 0.2565938 | 1 | 0 | 0 | 3.4094783 | 4.6377803 | ADRA2A |
| 62 | sulfate transmembrane transporter activity (GO:0015116) | 1/14 | 0.2565938 | 1 | 0 | 0 | 3.4094783 | 4.6377803 | SLC26A2 |
| 63 | fucosyltransferase activity (GO:0008417) | 1/14 | 0.2565938 | 1 | 0 | 0 | 3.4094783 | 4.6377803 | FUT6 |
| 64 | phosphatidylinositol-4-phosphate binding (GO:0070273) | 1/14 | 0.2565938 | 1 | 0 | 0 | 3.4094783 | 4.6377803 | JPH2 |
| 65 | chemokine activity (GO:0008009) | 2/47 | 0.2585036 | 1 | 0 | 0 | 2.0311786 | 2.7478708 | CCL24;CXCL2 |
| 66 | anion:cation symporter activity (GO:0015296) | 2/48 | 0.2663018 | 1 | 0 | 0 | 1.9888624 | 2.6315136 | SLC6A1;SLC13A5 |
| 67 | low-density lipoprotein particle binding (GO:0030169) | 1/15 | 0.2721791 | 1 | 0 | 0 | 3.1821798 | 4.1409551 | THBS1 |
| 68 | protein transmembrane transporter activity (GO:0008320) | 1/15 | 0.2721791 | 1 | 0 | 0 | 3.1821798 | 4.1409551 | AZGP1 |
| 69 | FMN binding (GO:0010181) | 1/15 | 0.2721791 | 1 | 0 | 0 | 3.1821798 | 4.1409551 | CREG2 |
| 70 | phospholipid-translocating ATPase activity (GO:0004012) | 1/15 | 0.2721791 | 1 | 0 | 0 | 3.1821798 | 4.1409551 | ATP10B |
| 71 | lipid transporter activity (GO:0005319) | 3/87 | 0.2748154 | 1 | 0 | 0 | 1.6459551 | 2.1260073 | ATP10B;ANO7;APOB |
| 72 | solute:sodium symporter activity (GO:0015370) | 2/50 | 0.2818931 | 1 | 0 | 0 | 1.9093079 | 2.4176177 | SLC6A1;SLC13A5 |
| 73 | transforming growth factor beta binding (GO:0050431) | 1/16 | 0.2874383 | 1 | 0 | 0 | 2.9832936 | 3.7194122 | THBS1 |
| 74 | steroid hydroxylase activity (GO:0008395) | 1/16 | 0.2874383 | 1 | 0 | 0 | 2.9832936 | 3.7194122 | CYP17A1 |
| 75 | calcium-release channel activity (GO:0015278) | 1/16 | 0.2874383 | 1 | 0 | 0 | 2.9832936 | 3.7194122 | JPH2 |
| 76 | triglyceride lipase activity (GO:0004806) | 1/16 | 0.2874383 | 1 | 0 | 0 | 2.9832936 | 3.7194122 | LIPG |
| 77 | cytokine activity (GO:0005125) | 6/213 | 0.2891544 | 1 | 0 | 0 | 1.3445830 | 1.6683513 | CCL24;LEFTY1;CSF3;BMP8A;IL19;CXCL2 |
| 78 | symporter activity (GO:0015293) | 4/130 | 0.2902174 | 1 | 0 | 0 | 1.4686984 | 1.8169632 | SLC25A18;SLC6A1;SLC13A5;SLC16A14 |
| 79 | macromolecule transmembrane transporter activity (GO:0022884) | 1/17 | 0.3023784 | 1 | 0 | 0 | 2.8078057 | 3.3583490 | AZGP1 |
| 80 | FK506 binding (GO:0005528) | 1/17 | 0.3023784 | 1 | 0 | 0 | 2.8078057 | 3.3583490 | FKBP5 |
| 81 | macrolide binding (GO:0005527) | 1/17 | 0.3023784 | 1 | 0 | 0 | 2.8078057 | 3.3583490 | FKBP5 |
| 82 | calcium-activated potassium channel activity (GO:0015269) | 1/17 | 0.3023784 | 1 | 0 | 0 | 2.8078057 | 3.3583490 | KCNN2 |
| 83 | heparan sulfate proteoglycan binding (GO:0043395) | 1/17 | 0.3023784 | 1 | 0 | 0 | 2.8078057 | 3.3583490 | COMP |
| 84 | peptide hormone receptor binding (GO:0051428) | 1/17 | 0.3023784 | 1 | 0 | 0 | 2.8078057 | 3.3583490 | PTHLH |
| 85 | modified amino acid binding (GO:0072341) | 2/53 | 0.3052188 | 1 | 0 | 0 | 1.8012338 | 2.1375715 | JPH2;THBS1 |
| 86 | transmembrane receptor protein phosphatase activity (GO:0019198) | 1/18 | 0.3170060 | 1 | 0 | 0 | 2.6518165 | 3.0464985 | PTPRH |
| 87 | transmembrane receptor protein tyrosine phosphatase activity (GO:0005001) | 1/18 | 0.3170060 | 1 | 0 | 0 | 2.6518165 | 3.0464985 | PTPRH |
| 88 | HMG box domain binding (GO:0071837) | 1/18 | 0.3170060 | 1 | 0 | 0 | 2.6518165 | 3.0464985 | PAX6 |
| 89 | pattern binding (GO:0001871) | 1/18 | 0.3170060 | 1 | 0 | 0 | 2.6518165 | 3.0464985 | REG4 |
| 90 | cysteine-type endopeptidase activator activity involved in apoptotic process (GO:0008656) | 1/18 | 0.3170060 | 1 | 0 | 0 | 2.6518165 | 3.0464985 | NKX3-1 |
| 91 | acetylcholine receptor activity (GO:0015464) | 1/18 | 0.3170060 | 1 | 0 | 0 | 2.6518165 | 3.0464985 | CHRM1 |
| 92 | lipoprotein particle receptor binding (GO:0070325) | 1/18 | 0.3170060 | 1 | 0 | 0 | 2.6518165 | 3.0464985 | APOB |
| 93 | polysaccharide binding (GO:0030247) | 1/18 | 0.3170060 | 1 | 0 | 0 | 2.6518165 | 3.0464985 | REG4 |
| 94 | calcium-dependent protein binding (GO:0048306) | 2/56 | 0.3284002 | 1 | 0 | 0 | 1.7047392 | 1.8982650 | TNNI3;SYT8 |
| 95 | histone acetyltransferase binding (GO:0035035) | 1/19 | 0.3313276 | 1 | 0 | 0 | 2.5122472 | 2.7751481 | PAX6 |
| 96 | adrenergic receptor binding (GO:0031690) | 1/19 | 0.3313276 | 1 | 0 | 0 | 2.5122472 | 2.7751481 | ADRA2A |
| 97 | neurotransmitter:sodium symporter activity (GO:0005328) | 1/19 | 0.3313276 | 1 | 0 | 0 | 2.5122472 | 2.7751481 | SLC6A1 |
| 98 | chemokine receptor binding (GO:0042379) | 2/57 | 0.3360828 | 1 | 0 | 0 | 1.6748315 | 1.8262323 | CCL24;CXCL2 |
| 99 | carbohydrate kinase activity (GO:0019200) | 1/20 | 0.3453496 | 1 | 0 | 0 | 2.3866348 | 2.5374656 | HKDC1 |
| 100 | fibroblast growth factor binding (GO:0017134) | 1/20 | 0.3453496 | 1 | 0 | 0 | 2.3866348 | 2.5374656 | THBS1 |
| 101 | UDP-galactosyltransferase activity (GO:0035250) | 1/20 | 0.3453496 | 1 | 0 | 0 | 2.3866348 | 2.5374656 | ABO |
| 102 | alpha-actinin binding (GO:0051393) | 1/20 | 0.3453496 | 1 | 0 | 0 | 2.3866348 | 2.5374656 | KCNN2 |
| 103 | ankyrin binding (GO:0030506) | 1/21 | 0.3590782 | 1 | 0 | 0 | 2.2729856 | 2.3280260 | FLNC |
| 104 | aromatase activity (GO:0070330) | 1/21 | 0.3590782 | 1 | 0 | 0 | 2.2729856 | 2.3280260 | CYP3A5 |
| 105 | peptidase activator activity involved in apoptotic process (GO:0016505) | 1/21 | 0.3590782 | 1 | 0 | 0 | 2.2729856 | 2.3280260 | NKX3-1 |
| 106 | glycosaminoglycan binding (GO:0005539) | 5/190 | 0.3672648 | 1 | 0 | 0 | 1.2561236 | 1.2582240 | COMP;REG4;LIPG;APOB;THBS1 |
| 107 | secondary active transmembrane transporter activity (GO:0015291) | 5/191 | 0.3714210 | 1 | 0 | 0 | 1.2495470 | 1.2375754 | SLC26A2;SLC25A18;SLC6A1;SLC13A5;SLC16A14 |
| 108 | phosphatidylinositol-3-phosphate binding (GO:0032266) | 1/22 | 0.3725196 | 1 | 0 | 0 | 2.1696680 | 2.1424725 | JPH2 |
| 109 | transforming growth factor beta receptor binding (GO:0005160) | 1/22 | 0.3725196 | 1 | 0 | 0 | 2.1696680 | 2.1424725 | LEFTY1 |
| 110 | R-SMAD binding (GO:0070412) | 1/22 | 0.3725196 | 1 | 0 | 0 | 2.1696680 | 2.1424725 | PAX6 |
| 111 | Hsp70 protein binding (GO:0030544) | 1/22 | 0.3725196 | 1 | 0 | 0 | 2.1696680 | 2.1424725 | GPR37 |
| 112 | heat shock protein binding (GO:0031072) | 2/63 | 0.3815500 | 1 | 0 | 0 | 1.5153237 | 1.4600346 | GPR37;FKBP5 |
| 113 | glycolipid binding (GO:0051861) | 1/23 | 0.3856798 | 1 | 0 | 0 | 2.0753346 | 1.9772706 | CEACAM5 |
| 114 | RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription (GO:0001205) | 1/23 | 0.3856798 | 1 | 0 | 0 | 2.0753346 | 1.9772706 | SIX3 |
| 115 | purinergic receptor activity (GO:0035586) | 1/23 | 0.3856798 | 1 | 0 | 0 | 2.0753346 | 1.9772706 | ADORA3 |
| 116 | metallocarboxypeptidase activity (GO:0004181) | 1/24 | 0.3985646 | 1 | 0 | 0 | 1.9888624 | 1.8295261 | CPE |
| 117 | lipoprotein particle binding (GO:0071813) | 1/24 | 0.3985646 | 1 | 0 | 0 | 1.9888624 | 1.8295261 | THBS1 |
| 118 | protein-lipid complex binding (GO:0071814) | 1/24 | 0.3985646 | 1 | 0 | 0 | 1.9888624 | 1.8295261 | THBS1 |
| 119 | neurotransmitter transporter activity (GO:0005326) | 1/24 | 0.3985646 | 1 | 0 | 0 | 1.9888624 | 1.8295261 | SLC6A1 |
| 120 | dicarboxylic acid transmembrane transporter activity (GO:0005310) | 1/24 | 0.3985646 | 1 | 0 | 0 | 1.9888624 | 1.8295261 | SLC13A5 |
| 121 | anion transmembrane transporter activity (GO:0008509) | 6/245 | 0.4076792 | 1 | 0 | 0 | 1.1689640 | 1.0488818 | ANO1;SLC26A2;SLCO1B3;ANO7;SLC6A1;SLC13A5 |
| 122 | Rho GTPase binding (GO:0017048) | 2/67 | 0.4111207 | 1 | 0 | 0 | 1.4248566 | 1.2665099 | DAAM2;CDC42EP5 |
| 123 | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen (GO:0016712) | 1/25 | 0.4111798 | 1 | 0 | 0 | 1.9093079 | 1.6968492 | CYP3A5 |
| 124 | steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor (GO:0033764) | 1/25 | 0.4111798 | 1 | 0 | 0 | 1.9093079 | 1.6968492 | HSD11B2 |
| 125 | actinin binding (GO:0042805) | 1/25 | 0.4111798 | 1 | 0 | 0 | 1.9093079 | 1.6968492 | KCNN2 |
| 126 | sulfur compound transmembrane transporter activity (GO:1901682) | 1/26 | 0.4235310 | 1 | 0 | 0 | 1.8358730 | 1.5772510 | SLC26A2 |
| 127 | fibronectin binding (GO:0001968) | 1/26 | 0.4235310 | 1 | 0 | 0 | 1.8358730 | 1.5772510 | THBS1 |
| 128 | sulfur compound binding (GO:1901681) | 5/206 | 0.4335324 | 1 | 0 | 0 | 1.1585606 | 0.9683119 | COMP;REG4;LIPG;APOB;THBS1 |
| 129 | glutamate receptor activity (GO:0008066) | 1/27 | 0.4356237 | 1 | 0 | 0 | 1.7678777 | 1.4690648 | GRM8 |
| 130 | Wnt-protein binding (GO:0017147) | 1/27 | 0.4356237 | 1 | 0 | 0 | 1.7678777 | 1.4690648 | CTHRC1 |
| 131 | peptidase regulator activity (GO:0061134) | 5/209 | 0.4458296 | 1 | 0 | 0 | 1.1419305 | 0.9224727 | SERPINB4;AHSG;HMSD;SSPO;NKX3-1 |
| 132 | growth factor activity (GO:0008083) | 4/163 | 0.4461966 | 1 | 0 | 0 | 1.1713545 | 0.9452780 | CSF3;LEFTY1;BMP8A;TFF1 |
| 133 | chloride channel activity (GO:0005254) | 2/72 | 0.4470730 | 1 | 0 | 0 | 1.3259082 | 1.0674003 | ANO1;ANO7 |
| 134 | phosphatidylinositol phospholipase C activity (GO:0004435) | 1/28 | 0.4474633 | 1 | 0 | 0 | 1.7047392 | 1.3708842 | CHRM1 |
| 135 | steroid dehydrogenase activity (GO:0016229) | 1/28 | 0.4474633 | 1 | 0 | 0 | 1.7047392 | 1.3708842 | HSD11B2 |
| 136 | estrogen receptor binding (GO:0030331) | 1/28 | 0.4474633 | 1 | 0 | 0 | 1.7047392 | 1.3708842 | NKX3-1 |
| 137 | inorganic anion transmembrane transporter activity (GO:0015103) | 3/119 | 0.4561068 | 1 | 0 | 0 | 1.2033453 | 0.9446602 | ANO1;SLC26A2;ANO7 |
| 138 | kinesin binding (GO:0019894) | 1/29 | 0.4590552 | 1 | 0 | 0 | 1.6459551 | 1.2815157 | NEK6 |
| 139 | phospholipase C activity (GO:0004629) | 1/30 | 0.4704044 | 1 | 0 | 0 | 1.5910899 | 1.1999403 | CHRM1 |
| 140 | monocarboxylic acid transmembrane transporter activity (GO:0008028) | 1/30 | 0.4704044 | 1 | 0 | 0 | 1.5910899 | 1.1999403 | SLC6A1 |
| 141 | phosphatidylinositol-3,4,5-trisphosphate binding (GO:0005547) | 1/30 | 0.4704044 | 1 | 0 | 0 | 1.5910899 | 1.1999403 | JPH2 |
| 142 | laminin binding (GO:0043236) | 1/30 | 0.4704044 | 1 | 0 | 0 | 1.5910899 | 1.1999403 | THBS1 |
| 143 | growth factor binding (GO:0019838) | 3/123 | 0.4777203 | 1 | 0 | 0 | 1.1642121 | 0.8600382 | NTRK2;PXDN;THBS1 |
| 144 | oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor (GO:0016620) | 1/31 | 0.4815161 | 1 | 0 | 0 | 1.5397644 | 1.1252839 | ALDH1L2 |
| 145 | ephrin receptor binding (GO:0046875) | 1/31 | 0.4815161 | 1 | 0 | 0 | 1.5397644 | 1.1252839 | NTRK2 |
| 146 | calcium channel regulator activity (GO:0005246) | 1/31 | 0.4815161 | 1 | 0 | 0 | 1.5397644 | 1.1252839 | TNNI3 |
| 147 | iron ion binding (GO:0005506) | 4/172 | 0.4874009 | 1 | 0 | 0 | 1.1100627 | 0.7977670 | LCN2;ALOX15B;CYP3A5;CYP17A1 |
| 148 | cytokine binding (GO:0019955) | 2/78 | 0.4885395 | 1 | 0 | 0 | 1.2239153 | 0.8767333 | PXDN;THBS1 |
| 149 | peptidase inhibitor activity (GO:0030414) | 4/173 | 0.4919047 | 1 | 0 | 0 | 1.1036462 | 0.7830041 | SERPINB4;AHSG;HMSD;SSPO |
| 150 | anion channel activity (GO:0005253) | 2/80 | 0.5019244 | 1 | 0 | 0 | 1.1933174 | 0.8225606 | ANO1;ANO7 |
| 151 | organic anion transmembrane transporter activity (GO:0008514) | 3/130 | 0.5145426 | 1 | 0 | 0 | 1.1015238 | 0.7319371 | SLCO1B3;SLC6A1;SLC13A5 |
| 152 | solute:cation symporter activity (GO:0015294) | 2/82 | 0.5150817 | 1 | 0 | 0 | 1.1642121 | 0.7723730 | SLC6A1;SLC13A5 |
| 153 | cytokine receptor binding (GO:0005126) | 5/228 | 0.5217758 | 1 | 0 | 0 | 1.0467697 | 0.6809418 | CCL24;LEFTY1;CSF3;PXDN;CXCL2 |
| 154 | peptide antigen binding (GO:0042605) | 1/35 | 0.5236849 | 1 | 0 | 0 | 1.3637913 | 0.8821891 | AZGP1 |
| 155 | acetylgalactosaminyltransferase activity (GO:0008376) | 1/35 | 0.5236849 | 1 | 0 | 0 | 1.3637913 | 0.8821891 | ABO |
| 156 | G-protein coupled receptor binding (GO:0001664) | 5/229 | 0.5256558 | 1 | 0 | 0 | 1.0421986 | 0.6702470 | CCL24;WNT16;CXCL2;ADRA2A;CTHRC1 |
| 157 | ATP-dependent DNA helicase activity (GO:0004003) | 1/36 | 0.5336812 | 1 | 0 | 0 | 1.3259082 | 0.8326130 | RTEL1-TNFRSF6B |
| 158 | protein phosphatase inhibitor activity (GO:0004864) | 1/36 | 0.5336812 | 1 | 0 | 0 | 1.3259082 | 0.8326130 | PHACTR3 |
| 159 | calcium-dependent phospholipid binding (GO:0005544) | 1/36 | 0.5336812 | 1 | 0 | 0 | 1.3259082 | 0.8326130 | DOC2B |
| 160 | chloride transmembrane transporter activity (GO:0015108) | 2/86 | 0.5406975 | 1 | 0 | 0 | 1.1100627 | 0.6825724 | ANO1;ANO7 |
| 161 | peptidase activator activity (GO:0016504) | 1/37 | 0.5434681 | 1 | 0 | 0 | 1.2900729 | 0.7866661 | NKX3-1 |
| 162 | dioxygenase activity (GO:0051213) | 2/87 | 0.5469535 | 1 | 0 | 0 | 1.0973034 | 0.6621035 | PTGS2;ALOX15B |
| 163 | RNA polymerase II regulatory region sequence-specific DNA binding (GO:0000977) | 6/284 | 0.5489403 | 1 | 0 | 0 | 1.0084373 | 0.6048260 | MUC1;CUX2;SIX3;PAX6;BHLHA15;FEZF1 |
| 164 | phosphatase inhibitor activity (GO:0019212) | 1/38 | 0.5530502 | 1 | 0 | 0 | 1.2561236 | 0.7440102 | PHACTR3 |
| 165 | metalloexopeptidase activity (GO:0008235) | 1/39 | 0.5624316 | 1 | 0 | 0 | 1.2239153 | 0.7043459 | CPE |
| 166 | cysteine-type endopeptidase regulator activity involved in apoptotic process (GO:0043028) | 1/39 | 0.5624316 | 1 | 0 | 0 | 1.2239153 | 0.7043459 | NKX3-1 |
| 167 | RNA polymerase II regulatory region DNA binding (GO:0001012) | 6/288 | 0.5626366 | 1 | 0 | 0 | 0.9944312 | 0.5719185 | MUC1;CUX2;SIX3;PAX6;BHLHA15;FEZF1 |
| 168 | phospholipase activity (GO:0004620) | 2/90 | 0.5653620 | 1 | 0 | 0 | 1.0607266 | 0.6049208 | CHRM1;LIPG |
| 169 | transcription regulatory region sequence-specific DNA binding (GO:0000976) | 7/340 | 0.5715885 | 1 | 0 | 0 | 0.9827320 | 0.5496773 | MUC1;CUX2;SIX3;PAX6;BHLHA15;FEZF1;NKX3-1 |
| 170 | protein self-association (GO:0043621) | 1/40 | 0.5716165 | 1 | 0 | 0 | 1.1933174 | 0.6674069 | NKX3-1 |
| 171 | carboxypeptidase activity (GO:0004180) | 1/40 | 0.5716165 | 1 | 0 | 0 | 1.1933174 | 0.6674069 | CPE |
| 172 | peptidyl-prolyl cis-trans isomerase activity (GO:0003755) | 1/41 | 0.5806091 | 1 | 0 | 0 | 1.1642121 | 0.6329560 | FKBP5 |
| 173 | phosphatidylinositol-4,5-bisphosphate binding (GO:0005546) | 1/41 | 0.5806091 | 1 | 0 | 0 | 1.1642121 | 0.6329560 | JPH2 |
| 174 | drug binding (GO:0008144) | 2/93 | 0.5832269 | 1 | 0 | 0 | 1.0265096 | 0.5534724 | CHRM1;FKBP5 |
| 175 | oxidoreductase activity, acting on the aldehyde or oxo group of donors (GO:0016903) | 1/42 | 0.5894134 | 1 | 0 | 0 | 1.1364928 | 0.6007814 | ALDH1L2 |
| 176 | receptor regulator activity (GO:0030545) | 1/42 | 0.5894134 | 1 | 0 | 0 | 1.1364928 | 0.6007814 | PXDN |
| 177 | RNA polymerase II core promoter sequence-specific DNA binding (GO:0000979) | 1/43 | 0.5980332 | 1 | 0 | 0 | 1.1100627 | 0.5706932 | PAX6 |
| 178 | cis-trans isomerase activity (GO:0016859) | 1/43 | 0.5980332 | 1 | 0 | 0 | 1.1100627 | 0.5706932 | FKBP5 |
| 179 | acetylglucosaminyltransferase activity (GO:0008375) | 1/44 | 0.6064726 | 1 | 0 | 0 | 1.0848340 | 0.5425209 | B3GNT6 |
| 180 | syntaxin binding (GO:0019905) | 1/44 | 0.6064726 | 1 | 0 | 0 | 1.0848340 | 0.5425209 | STXBP5L |
| 181 | voltage-gated calcium channel activity (GO:0005245) | 1/44 | 0.6064726 | 1 | 0 | 0 | 1.0848340 | 0.5425209 | CACNA1E |
| 182 | actin filament binding (GO:0051015) | 2/98 | 0.6117869 | 1 | 0 | 0 | 0.9741367 | 0.4786628 | SHROOM1;FLNC |
| 183 | serine-type endopeptidase inhibitor activity (GO:0004867) | 2/98 | 0.6117869 | 1 | 0 | 0 | 0.9741367 | 0.4786628 | SERPINB4;HMSD |
| 184 | monooxygenase activity (GO:0004497) | 2/99 | 0.6173166 | 1 | 0 | 0 | 0.9642969 | 0.4651511 | CYP3A5;CYP17A1 |
| 185 | active transmembrane transporter activity (GO:0022804) | 6/307 | 0.6248122 | 1 | 0 | 0 | 0.9328866 | 0.4387404 | SLC26A2;SLC25A18;ATP10B;SLC6A1;SLC13A5;SLC16A14 |
| 186 | carboxylic acid transmembrane transporter activity (GO:0046943) | 2/101 | 0.6281942 | 1 | 0 | 0 | 0.9452019 | 0.4394299 | SLC6A1;SLC13A5 |
| 187 | channel regulator activity (GO:0016247) | 2/102 | 0.6335424 | 1 | 0 | 0 | 0.9359352 | 0.4271873 | ANKRD36C;TNNI3 |
| 188 | organic acid transmembrane transporter activity (GO:0005342) | 2/104 | 0.6440582 | 1 | 0 | 0 | 0.9179365 | 0.4038609 | SLC6A1;SLC13A5 |
| 189 | protein kinase activator activity (GO:0030295) | 1/49 | 0.6460903 | 1 | 0 | 0 | 0.9741367 | 0.4255184 | NKX3-1 |
| 190 | cysteine-type endopeptidase inhibitor activity (GO:0004869) | 1/49 | 0.6460903 | 1 | 0 | 0 | 0.9741367 | 0.4255184 | AHSG |
| 191 | lipase activity (GO:0016298) | 2/105 | 0.6492262 | 1 | 0 | 0 | 0.9091942 | 0.3927483 | CHRM1;LIPG |
| 192 | ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity (GO:0004879) | 1/50 | 0.6535229 | 1 | 0 | 0 | 0.9546539 | 0.4060885 | NKX3-1 |
| 193 | NAD binding (GO:0051287) | 1/50 | 0.6535229 | 1 | 0 | 0 | 0.9546539 | 0.4060885 | HSD11B2 |
| 194 | direct ligand regulated sequence-specific DNA binding transcription factor activity (GO:0098531) | 1/50 | 0.6535229 | 1 | 0 | 0 | 0.9546539 | 0.4060885 | NKX3-1 |
| 195 | amino acid binding (GO:0016597) | 2/107 | 0.6593834 | 1 | 0 | 0 | 0.8921999 | 0.3715567 | JPH2;THBS1 |
| 196 | DNA helicase activity (GO:0003678) | 1/51 | 0.6607998 | 1 | 0 | 0 | 0.9359352 | 0.3877621 | RTEL1-TNFRSF6B |
| 197 | extracellular matrix binding (GO:0050840) | 1/51 | 0.6607998 | 1 | 0 | 0 | 0.9359352 | 0.3877621 | THBS1 |
| 198 | carbon-carbon lyase activity (GO:0016830) | 1/51 | 0.6607998 | 1 | 0 | 0 | 0.9359352 | 0.3877621 | CYP17A1 |
| 199 | calcium channel activity (GO:0005262) | 2/108 | 0.6643731 | 1 | 0 | 0 | 0.8839388 | 0.3614526 | JPH2;CACNA1E |
| 200 | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen (GO:0016705) | 3/163 | 0.6670891 | 1 | 0 | 0 | 0.8785159 | 0.3556511 | PTGS2;CYP3A5;CYP17A1 |
| 201 | sulfotransferase activity (GO:0008146) | 1/52 | 0.6679242 | 1 | 0 | 0 | 0.9179365 | 0.3704614 | SULT1C2 |
| 202 | double-stranded DNA binding (GO:0003690) | 2/109 | 0.6693038 | 1 | 0 | 0 | 0.8758293 | 0.3516605 | ZBTB16;PAX6 |
| 203 | copper ion binding (GO:0005507) | 1/53 | 0.6748993 | 1 | 0 | 0 | 0.9006169 | 0.3541152 | F5 |
| 204 | core promoter binding (GO:0001047) | 2/111 | 0.6789896 | 1 | 0 | 0 | 0.8600486 | 0.3329674 | PAX6;NKX3-1 |
| 205 | endopeptidase inhibitor activity (GO:0004866) | 3/166 | 0.6790707 | 1 | 0 | 0 | 0.8626391 | 0.3338672 | SERPINB4;AHSG;HMSD |
| 206 | RNA polymerase II core promoter proximal region sequence-specific DNA binding (GO:0000978) | 3/167 | 0.6829931 | 1 | 0 | 0 | 0.8574736 | 0.3269295 | MUC1;PAX6;FEZF1 |
| 207 | kinase activator activity (GO:0019209) | 1/55 | 0.6884140 | 1 | 0 | 0 | 0.8678672 | 0.3240311 | NKX3-1 |
| 208 | RNA polymerase II distal enhancer sequence-specific DNA binding (GO:0000980) | 1/56 | 0.6949597 | 1 | 0 | 0 | 0.8523696 | 0.3101785 | SIX3 |
| 209 | phosphatidylinositol bisphosphate binding (GO:1902936) | 1/56 | 0.6949597 | 1 | 0 | 0 | 0.8523696 | 0.3101785 | JPH2 |
| 210 | p53 binding (GO:0002039) | 1/56 | 0.6949597 | 1 | 0 | 0 | 0.8523696 | 0.3101785 | MUC1 |
| 211 | endopeptidase regulator activity (GO:0061135) | 3/171 | 0.6983256 | 1 | 0 | 0 | 0.8374157 | 0.3006907 | SERPINB4;AHSG;HMSD |
| 212 | steroid hormone receptor activity (GO:0003707) | 1/57 | 0.7013682 | 1 | 0 | 0 | 0.8374157 | 0.2970500 | NKX3-1 |
| 213 | kinase inhibitor activity (GO:0019210) | 1/57 | 0.7013682 | 1 | 0 | 0 | 0.8374157 | 0.2970500 | AHSG |
| 214 | SNARE binding (GO:0000149) | 1/59 | 0.7137851 | 1 | 0 | 0 | 0.8090288 | 0.2727830 | STXBP5L |
| 215 | core promoter proximal region sequence-specific DNA binding (GO:0000987) | 3/176 | 0.7166933 | 1 | 0 | 0 | 0.8136255 | 0.2710246 | MUC1;PAX6;FEZF1 |
| 216 | core promoter proximal region DNA binding (GO:0001159) | 3/178 | 0.7237942 | 1 | 0 | 0 | 0.8044837 | 0.2600478 | MUC1;PAX6;FEZF1 |
| 217 | transferase activity, transferring sulfur-containing groups (GO:0016782) | 1/64 | 0.7426200 | 1 | 0 | 0 | 0.7458234 | 0.2219352 | SULT1C2 |
| 218 | phospholipid binding (GO:0005543) | 5/296 | 0.7459211 | 1 | 0 | 0 | 0.8062956 | 0.2363538 | JPH2;CEACAM5;DOC2B;APOB;THBS1 |
| 219 | transmembrane receptor protein tyrosine kinase activity (GO:0004714) | 1/65 | 0.7480294 | 1 | 0 | 0 | 0.7343492 | 0.2131911 | NTRK2 |
| 220 | protein phosphatase regulator activity (GO:0019888) | 1/65 | 0.7480294 | 1 | 0 | 0 | 0.7343492 | 0.2131911 | PHACTR3 |
| 221 | cation-transporting ATPase activity (GO:0019829) | 1/65 | 0.7480294 | 1 | 0 | 0 | 0.7343492 | 0.2131911 | ATP10B |
| 222 | calcium ion transmembrane transporter activity (GO:0015085) | 2/127 | 0.7483486 | 1 | 0 | 0 | 0.7516960 | 0.2179064 | JPH2;CACNA1E |
| 223 | sodium ion transmembrane transporter activity (GO:0015081) | 2/128 | 0.7522246 | 1 | 0 | 0 | 0.7458234 | 0.2123511 | SLC6A1;SLC13A5 |
| 224 | amino acid transmembrane transporter activity (GO:0015171) | 1/66 | 0.7533254 | 1 | 0 | 0 | 0.7232227 | 0.2048586 | SLC6A1 |
| 225 | ATPase activity, coupled to transmembrane movement of ions (GO:0042625) | 1/67 | 0.7585103 | 1 | 0 | 0 | 0.7124283 | 0.1969144 | ATP10B |
| 226 | steroid hormone receptor binding (GO:0035258) | 1/67 | 0.7585103 | 1 | 0 | 0 | 0.7124283 | 0.1969144 | NKX3-1 |
| 227 | magnesium ion binding (GO:0000287) | 3/190 | 0.7635108 | 1 | 0 | 0 | 0.7536742 | 0.2033624 | NEK6;ATP10B;IRAK3 |
| 228 | SMAD binding (GO:0046332) | 1/68 | 0.7635865 | 1 | 0 | 0 | 0.7019514 | 0.1893366 | PAX6 |
| 229 | UDP-glycosyltransferase activity (GO:0008194) | 2/132 | 0.7672185 | 1 | 0 | 0 | 0.7232227 | 0.1916422 | B3GNT6;ABO |
| 230 | enhancer sequence-specific DNA binding (GO:0001158) | 1/70 | 0.7734217 | 1 | 0 | 0 | 0.6818957 | 0.1752000 | SIX3 |
| 231 | transferase activity, transferring hexosyl groups (GO:0016758) | 3/194 | 0.7756778 | 1 | 0 | 0 | 0.7381345 | 0.1874994 | FUT6;B3GNT6;ABO |
| 232 | core promoter sequence-specific DNA binding (GO:0001046) | 1/71 | 0.7781852 | 1 | 0 | 0 | 0.6722915 | 0.1686045 | PAX6 |
| 233 | neurotransmitter receptor activity (GO:0030594) | 1/74 | 0.7918844 | 1 | 0 | 0 | 0.6450364 | 0.1505127 | CHRM1 |
| 234 | phosphatase regulator activity (GO:0019208) | 1/75 | 0.7962606 | 1 | 0 | 0 | 0.6364360 | 0.1449984 | PHACTR3 |
| 235 | histone deacetylase binding (GO:0042826) | 1/75 | 0.7962606 | 1 | 0 | 0 | 0.6364360 | 0.1449984 | NKX3-1 |
| 236 | kinase regulator activity (GO:0019207) | 2/141 | 0.7980965 | 1 | 0 | 0 | 0.6770595 | 0.1526943 | AHSG;NKX3-1 |
| 237 | RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription (GO:0001228) | 3/202 | 0.7984723 | 1 | 0 | 0 | 0.7089014 | 0.1595418 | SIX3;PAX6;BHLHA15 |
| 238 | protease binding (GO:0002020) | 1/77 | 0.8047394 | 1 | 0 | 0 | 0.6199052 | 0.1346662 | COMP |
| 239 | gated channel activity (GO:0022836) | 5/323 | 0.8098460 | 1 | 0 | 0 | 0.7388962 | 0.1558415 | ANO1;JPH2;KCNN2;ANO7;CACNA1E |
| 240 | DNA-dependent ATPase activity (GO:0008094) | 1/80 | 0.8168022 | 1 | 0 | 0 | 0.5966587 | 0.1207388 | RTEL1-TNFRSF6B |
| 241 | vitamin binding (GO:0019842) | 1/80 | 0.8168022 | 1 | 0 | 0 | 0.5966587 | 0.1207388 | TCN1 |
| 242 | protein transporter activity (GO:0008565) | 1/81 | 0.8206556 | 1 | 0 | 0 | 0.5892926 | 0.1164747 | AZGP1 |
| 243 | actin binding (GO:0003779) | 6/386 | 0.8221131 | 1 | 0 | 0 | 0.7419590 | 0.1453330 | SNTG2;DAAM2;PHACTR3;TNNI3;FLNC;SHROOM1 |
| 244 | transmembrane receptor protein kinase activity (GO:0019199) | 1/82 | 0.8244281 | 1 | 0 | 0 | 0.5821061 | 0.1123845 | NTRK2 |
| 245 | steroid binding (GO:0005496) | 1/82 | 0.8244281 | 1 | 0 | 0 | 0.5821061 | 0.1123845 | HSD11B2 |
| 246 | helicase activity (GO:0004386) | 2/150 | 0.8252959 | 1 | 0 | 0 | 0.6364360 | 0.1222042 | RTEL1-TNFRSF6B;DQX1 |
| 247 | enhancer binding (GO:0035326) | 1/83 | 0.8281214 | 1 | 0 | 0 | 0.5750927 | 0.1084599 | SIX3 |
| 248 | RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity (GO:0003705) | 1/84 | 0.8317373 | 1 | 0 | 0 | 0.5682464 | 0.1046930 | SIX3 |
| 249 | cytokine receptor activity (GO:0004896) | 1/85 | 0.8352772 | 1 | 0 | 0 | 0.5615611 | 0.1010763 | IL1R2 |
| 250 | enzyme inhibitor activity (GO:0004857) | 5/336 | 0.8357199 | 1 | 0 | 0 | 0.7103080 | 0.1274731 | SERPINB4;AHSG;HMSD;PHACTR3;SSPO |
| 251 | divalent inorganic cation transmembrane transporter activity (GO:0072509) | 2/154 | 0.8362938 | 1 | 0 | 0 | 0.6199052 | 0.1108237 | JPH2;CACNA1E |
| 252 | ribonuclease activity (GO:0004540) | 1/86 | 0.8387428 | 1 | 0 | 0 | 0.5550314 | 0.0976029 | AZGP1 |
| 253 | purine NTP-dependent helicase activity (GO:0070035) | 1/89 | 0.8487093 | 1 | 0 | 0 | 0.5363224 | 0.0879775 | RTEL1-TNFRSF6B |
| 254 | ATP-dependent helicase activity (GO:0008026) | 1/89 | 0.8487093 | 1 | 0 | 0 | 0.5363224 | 0.0879775 | RTEL1-TNFRSF6B |
| 255 | cation channel activity (GO:0005261) | 4/285 | 0.8509126 | 1 | 0 | 0 | 0.6699326 | 0.1081579 | ANO1;JPH2;KCNN2;CACNA1E |
| 256 | hormone receptor binding (GO:0051427) | 2/160 | 0.8516207 | 1 | 0 | 0 | 0.5966587 | 0.0958317 | PTHLH;NKX3-1 |
| 257 | phosphoric diester hydrolase activity (GO:0008081) | 1/90 | 0.8518930 | 1 | 0 | 0 | 0.5303633 | 0.0850142 | CHRM1 |
| 258 | phosphatidylinositol phosphate binding (GO:1901981) | 1/91 | 0.8550098 | 1 | 0 | 0 | 0.5245351 | 0.0821644 | JPH2 |
| 259 | protein C-terminus binding (GO:0008022) | 2/162 | 0.8564324 | 1 | 0 | 0 | 0.5892926 | 0.0913285 | ZBTB16;FIGN |
| 260 | calcium ion binding (GO:0005509) | 11/698 | 0.8691675 | 1 | 0 | 0 | 0.7522345 | 0.1054778 | COMP;FBN2;CGREF1;TPO;REG4;PCDH15;CDH15;ALOX15B;CACNA1E;NID2;THBS1 |
| 261 | PDZ domain binding (GO:0030165) | 1/96 | 0.8696394 | 1 | 0 | 0 | 0.4972156 | 0.0694494 | SNTG2 |
| 262 | cell adhesion molecule binding (GO:0050839) | 2/168 | 0.8700252 | 1 | 0 | 0 | 0.5682464 | 0.0791187 | CPE;THBS1 |
| 263 | calmodulin binding (GO:0005516) | 2/170 | 0.8742870 | 1 | 0 | 0 | 0.5615611 | 0.0754438 | PNCK;KCNN2 |
| 264 | peptide binding (GO:0042277) | 2/172 | 0.8784200 | 1 | 0 | 0 | 0.5550314 | 0.0719490 | AZGP1;GPR37 |
| 265 | protein homodimerization activity (GO:0042803) | 10/653 | 0.8812457 | 1 | 0 | 0 | 0.7309755 | 0.0924090 | NTRK2;ANO1;CDSN;ZBTB16;CEACAM5;KCNN2;IRAK3;BHLHA15;PTGS2;ADRA2A |
| 266 | integrin binding (GO:0005178) | 1/102 | 0.8852638 | 1 | 0 | 0 | 0.4679676 | 0.0570310 | THBS1 |
| 267 | protein tyrosine phosphatase activity (GO:0004725) | 1/103 | 0.8876798 | 1 | 0 | 0 | 0.4634242 | 0.0552143 | PTPRH |
| 268 | amide binding (GO:0033218) | 2/177 | 0.8882102 | 1 | 0 | 0 | 0.5393525 | 0.0639385 | AZGP1;GPR37 |
| 269 | ATPase activity, coupled to transmembrane movement of substances (GO:0042626) | 1/104 | 0.8900451 | 1 | 0 | 0 | 0.4589682 | 0.0534621 | ATP10B |
| 270 | phosphatidylinositol binding (GO:0035091) | 2/178 | 0.8900786 | 1 | 0 | 0 | 0.5363224 | 0.0624523 | JPH2;CEACAM5 |
| 271 | ATPase activity, coupled to movement of substances (GO:0043492) | 1/105 | 0.8923606 | 1 | 0 | 0 | 0.4545971 | 0.0517718 | ATP10B |
| 272 | metalloendopeptidase activity (GO:0004222) | 1/106 | 0.8946275 | 1 | 0 | 0 | 0.4503085 | 0.0501409 | ADAMDEC1 |
| 273 | small conjugating protein ligase binding (GO:0044389) | 2/182 | 0.8972662 | 1 | 0 | 0 | 0.5245351 | 0.0568610 | GPR37;PAX6 |
| 274 | ubiquitin protein ligase binding (GO:0031625) | 2/182 | 0.8972662 | 1 | 0 | 0 | 0.5245351 | 0.0568610 | GPR37;PAX6 |
| 275 | hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances (GO:0016820) | 1/108 | 0.8990194 | 1 | 0 | 0 | 0.4419694 | 0.0470479 | ATP10B |
| 276 | primary active transmembrane transporter activity (GO:0015399) | 1/111 | 0.9052673 | 1 | 0 | 0 | 0.4300243 | 0.0427982 | ATP10B |
| 277 | P-P-bond-hydrolysis-driven transmembrane transporter activity (GO:0015405) | 1/111 | 0.9052673 | 1 | 0 | 0 | 0.4300243 | 0.0427982 | ATP10B |
| 278 | exopeptidase activity (GO:0008238) | 1/111 | 0.9052673 | 1 | 0 | 0 | 0.4300243 | 0.0427982 | CPE |
| 279 | carboxylic ester hydrolase activity (GO:0052689) | 1/111 | 0.9052673 | 1 | 0 | 0 | 0.4300243 | 0.0427982 | LIPG |
| 280 | metallopeptidase activity (GO:0008237) | 2/188 | 0.9072319 | 1 | 0 | 0 | 0.5077946 | 0.0494375 | ADAMDEC1;CPE |
| 281 | serine-type peptidase activity (GO:0008236) | 2/188 | 0.9072319 | 1 | 0 | 0 | 0.5077946 | 0.0494375 | PRSS16;PLAT |
| 282 | coenzyme binding (GO:0050662) | 2/188 | 0.9072319 | 1 | 0 | 0 | 0.5077946 | 0.0494375 | HSD11B2;CREG2 |
| 283 | serine hydrolase activity (GO:0017171) | 2/191 | 0.9118692 | 1 | 0 | 0 | 0.4998188 | 0.0461126 | PRSS16;PLAT |
| 284 | oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor (GO:0016616) | 1/115 | 0.9130018 | 1 | 0 | 0 | 0.4150669 | 0.0377783 | HSD11B2 |
| 285 | Ras GTPase binding (GO:0017016) | 2/193 | 0.9148392 | 1 | 0 | 0 | 0.4946393 | 0.0440263 | DAAM2;CDC42EP5 |
| 286 | potassium channel activity (GO:0005267) | 1/118 | 0.9183864 | 1 | 0 | 0 | 0.4045144 | 0.0344392 | KCNN2 |
| 287 | ion channel activity (GO:0005216) | 5/396 | 0.9204088 | 1 | 0 | 0 | 0.6026856 | 0.0499851 | ANO1;JPH2;KCNN2;ANO7;CACNA1E |
| 288 | sequence-specific DNA binding RNA polymerase II transcription factor activity (GO:0000981) | 5/397 | 0.9214137 | 1 | 0 | 0 | 0.6011675 | 0.0492032 | SIX3;PAX6;BHLHA15;SPDEF;NKX3-1 |
| 289 | G-protein coupled peptide receptor activity (GO:0008528) | 1/121 | 0.9234384 | 1 | 0 | 0 | 0.3944851 | 0.0314212 | GPR37 |
| 290 | growth factor receptor binding (GO:0070851) | 1/121 | 0.9234384 | 1 | 0 | 0 | 0.3944851 | 0.0314212 | CSF3 |
| 291 | protein kinase regulator activity (GO:0019887) | 1/121 | 0.9234384 | 1 | 0 | 0 | 0.3944851 | 0.0314212 | NKX3-1 |
| 292 | metal ion transmembrane transporter activity (GO:0046873) | 5/400 | 0.9243615 | 1 | 0 | 0 | 0.5966587 | 0.0469284 | JPH2;KCNN2;SLC6A1;SLC13A5;CACNA1E |
| 293 | carboxylic acid binding (GO:0031406) | 2/200 | 0.9245113 | 1 | 0 | 0 | 0.4773270 | 0.0374654 | JPH2;THBS1 |
| 294 | organic acid binding (GO:0043177) | 2/201 | 0.9258056 | 1 | 0 | 0 | 0.4749522 | 0.0366145 | JPH2;THBS1 |
| 295 | peptide receptor activity (GO:0001653) | 1/123 | 0.9266318 | 1 | 0 | 0 | 0.3880707 | 0.0295706 | GPR37 |
| 296 | substrate-specific channel activity (GO:0022838) | 5/406 | 0.9299649 | 1 | 0 | 0 | 0.5878411 | 0.0426822 | ANO1;JPH2;KCNN2;ANO7;CACNA1E |
| 297 | transferase activity, transferring glycosyl groups (GO:0016757) | 3/280 | 0.9350530 | 1 | 0 | 0 | 0.5114218 | 0.0343430 | FUT6;B3GNT6;ABO |
| 298 | small GTPase binding (GO:0031267) | 2/209 | 0.9354316 | 1 | 0 | 0 | 0.4567722 | 0.0304883 | DAAM2;CDC42EP5 |
| 299 | oxidoreductase activity, acting on CH-OH group of donors (GO:0016614) | 1/131 | 0.9381306 | 1 | 0 | 0 | 0.3643717 | 0.0232710 | HSD11B2 |
| 300 | potassium ion transmembrane transporter activity (GO:0015079) | 1/138 | 0.9467066 | 1 | 0 | 0 | 0.3458891 | 0.0189430 | KCNN2 |
| 301 | channel activity (GO:0015267) | 5/427 | 0.9467779 | 1 | 0 | 0 | 0.5589309 | 0.0305683 | ANO1;JPH2;KCNN2;ANO7;CACNA1E |
| 302 | passive transmembrane transporter activity (GO:0022803) | 5/427 | 0.9467779 | 1 | 0 | 0 | 0.5589309 | 0.0305683 | ANO1;JPH2;KCNN2;ANO7;CACNA1E |
| 303 | GTPase binding (GO:0051020) | 2/221 | 0.9476823 | 1 | 0 | 0 | 0.4319701 | 0.0232123 | DAAM2;CDC42EP5 |
| 304 | nuclear hormone receptor binding (GO:0035257) | 1/139 | 0.9478308 | 1 | 0 | 0 | 0.3434007 | 0.0183992 | NKX3-1 |
| 305 | protein tyrosine kinase activity (GO:0004713) | 1/142 | 0.9510635 | 1 | 0 | 0 | 0.3361458 | 0.0168659 | NTRK2 |
| 306 | ligand-gated ion channel activity (GO:0015276) | 1/145 | 0.9540962 | 1 | 0 | 0 | 0.3291910 | 0.0154689 | JPH2 |
| 307 | ligand-gated channel activity (GO:0022834) | 1/145 | 0.9540962 | 1 | 0 | 0 | 0.3291910 | 0.0154689 | JPH2 |
| 308 | voltage-gated cation channel activity (GO:0022843) | 1/149 | 0.9578502 | 1 | 0 | 0 | 0.3203537 | 0.0137957 | CACNA1E |
| 309 | RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription (GO:0001077) | 1/151 | 0.9596107 | 1 | 0 | 0 | 0.3161106 | 0.0130325 | PAX6 |
| 310 | protein serine/threonine kinase activity (GO:0004674) | 5/449 | 0.9604014 | 1 | 0 | 0 | 0.5315445 | 0.0214765 | PNCK;PDPK2;NEK6;IRAK3;MYLK3 |
| 311 | structure-specific DNA binding (GO:0043566) | 2/241 | 0.9633299 | 1 | 0 | 0 | 0.3961220 | 0.0147989 | ZBTB16;PAX6 |
| 312 | isomerase activity (GO:0016853) | 1/159 | 0.9659489 | 1 | 0 | 0 | 0.3002056 | 0.0104004 | FKBP5 |
| 313 | serine-type endopeptidase activity (GO:0004252) | 1/167 | 0.9712944 | 1 | 0 | 0 | 0.2858245 | 0.0083248 | PLAT |
| 314 | microtubule binding (GO:0008017) | 1/171 | 0.9736444 | 1 | 0 | 0 | 0.2791386 | 0.0074556 | JAKMIP3 |
| 315 | phosphoprotein phosphatase activity (GO:0004721) | 1/172 | 0.9742013 | 1 | 0 | 0 | 0.2775157 | 0.0072535 | PTPRH |
| 316 | monovalent inorganic cation transmembrane transporter activity (GO:0015077) | 3/343 | 0.9761482 | 1 | 0 | 0 | 0.4174871 | 0.0100785 | KCNN2;SLC6A1;SLC13A5 |
| 317 | GTPase activator activity (GO:0005096) | 2/265 | 0.9762254 | 1 | 0 | 0 | 0.3602468 | 0.0086682 | ARHGAP40;ELMOD1 |
| 318 | cofactor binding (GO:0048037) | 2/266 | 0.9766543 | 1 | 0 | 0 | 0.3588925 | 0.0084780 | HSD11B2;CREG2 |
| 319 | kinase binding (GO:0019900) | 5/487 | 0.9766571 | 1 | 0 | 0 | 0.4900688 | 0.0115752 | NEK6;PAX6;TNNI3;ADRA2A;JAKMIP3 |
| 320 | lyase activity (GO:0016829) | 1/177 | 0.9768143 | 1 | 0 | 0 | 0.2696763 | 0.0063262 | CYP17A1 |
| 321 | ATPase activity, coupled (GO:0042623) | 2/272 | 0.9790748 | 1 | 0 | 0 | 0.3509757 | 0.0074222 | RTEL1-TNFRSF6B;ATP10B |
| 322 | inorganic cation transmembrane transporter activity (GO:0022890) | 5/497 | 0.9797583 | 1 | 0 | 0 | 0.4802082 | 0.0098200 | JPH2;KCNN2;SLC6A1;SLC13A5;CACNA1E |
| 323 | voltage-gated channel activity (GO:0022832) | 1/189 | 0.9820583 | 1 | 0 | 0 | 0.2525540 | 0.0045724 | CACNA1E |
| 324 | voltage-gated ion channel activity (GO:0005244) | 1/189 | 0.9820583 | 1 | 0 | 0 | 0.2525540 | 0.0045724 | CACNA1E |
| 325 | protein kinase binding (GO:0019901) | 4/437 | 0.9827203 | 1 | 0 | 0 | 0.4369126 | 0.0076157 | NEK6;PAX6;TNNI3;ADRA2A |
| 326 | nuclease activity (GO:0004518) | 1/195 | 0.9842180 | 1 | 0 | 0 | 0.2447831 | 0.0038940 | AZGP1 |
| 327 | RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity (GO:0000982) | 1/204 | 0.9869809 | 1 | 0 | 0 | 0.2339838 | 0.0030663 | PAX6 |
| 328 | transcription corepressor activity (GO:0003714) | 1/208 | 0.9880485 | 1 | 0 | 0 | 0.2294841 | 0.0027592 | TFCP2L1 |
| 329 | methyltransferase activity (GO:0008168) | 1/210 | 0.9885491 | 1 | 0 | 0 | 0.2272986 | 0.0026178 | ALDH1L2 |
| 330 | transcription factor binding (GO:0008134) | 4/464 | 0.9886529 | 1 | 0 | 0 | 0.4114888 | 0.0046959 | SIX3;PAX6;FOXA3;NKX3-1 |
| 331 | antigen binding (GO:0003823) | 1/212 | 0.9890288 | 1 | 0 | 0 | 0.2251542 | 0.0024839 | AZGP1 |
| 332 | GTPase regulator activity (GO:0030695) | 2/310 | 0.9896280 | 1 | 0 | 0 | 0.3079529 | 0.0032108 | ARHGAP40;ELMOD1 |
| 333 | transferase activity, transferring one-carbon groups (GO:0016741) | 1/218 | 0.9903507 | 1 | 0 | 0 | 0.2189573 | 0.0021230 | ALDH1L2 |
| 334 | GTPase activity (GO:0003924) | 1/224 | 0.9915137 | 1 | 0 | 0 | 0.2130924 | 0.0018161 | RAB43 |
| 335 | protein heterodimerization activity (GO:0046982) | 3/408 | 0.9919877 | 1 | 0 | 0 | 0.3509757 | 0.0028234 | ANO1;IRAK3;ADRA2A |
| 336 | nucleoside-triphosphatase regulator activity (GO:0060589) | 2/330 | 0.9928693 | 1 | 0 | 0 | 0.2892891 | 0.0020702 | ARHGAP40;ELMOD1 |
| 337 | tubulin binding (GO:0015631) | 1/241 | 0.9941033 | 1 | 0 | 0 | 0.1980610 | 0.0011714 | JAKMIP3 |
| 338 | enzyme activator activity (GO:0008047) | 3/446 | 0.9958542 | 1 | 0 | 0 | 0.3210720 | 0.0013339 | ARHGAP40;ELMOD1;NKX3-1 |
| 339 | phosphoric ester hydrolase activity (GO:0042578) | 2/360 | 0.9959591 | 1 | 0 | 0 | 0.2651816 | 0.0010737 | CHRM1;PTPRH |
| 340 | phosphatase activity (GO:0016791) | 1/266 | 0.9965494 | 1 | 0 | 0 | 0.1794462 | 0.0006203 | PTPRH |
| 341 | carbohydrate binding (GO:0030246) | 1/278 | 0.9973324 | 1 | 0 | 0 | 0.1717003 | 0.0004586 | REG4 |
| 342 | ubiquitin-protein transferase activity (GO:0004842) | 1/279 | 0.9973890 | 1 | 0 | 0 | 0.1710849 | 0.0004473 | PAX6 |
| 343 | ATPase activity (GO:0016887) | 2/395 | 0.9979329 | 1 | 0 | 0 | 0.2416845 | 0.0005001 | RTEL1-TNFRSF6B;ATP10B |
| 344 | transcription coactivator activity (GO:0003713) | 1/291 | 0.9979816 | 1 | 0 | 0 | 0.1640299 | 0.0003314 | SIX3 |
| 345 | endopeptidase activity (GO:0004175) | 2/411 | 0.9984821 | 1 | 0 | 0 | 0.2322759 | 0.0003528 | ADAMDEC1;PLAT |
| 346 | GTP binding (GO:0005525) | 1/385 | 0.9997308 | 1 | 0 | 0 | 0.1239810 | 0.0000334 | RAB43 |
| 347 | guanyl ribonucleotide binding (GO:0032561) | 1/405 | 0.9998241 | 1 | 0 | 0 | 0.1178585 | 0.0000207 | RAB43 |
| 348 | guanyl nucleotide binding (GO:0019001) | 1/406 | 0.9998278 | 1 | 0 | 0 | 0.1175682 | 0.0000202 | RAB43 |
| 349 | chromatin binding (GO:0003682) | 1/420 | 0.9998719 | 1 | 0 | 0 | 0.1136493 | 0.0000146 | PAX6 |
| 350 | ATP binding (GO:0005524) | 13/1494 | 0.9999555 | 1 | 0 | 0 | 0.4153448 | 0.0000185 | NTRK2;RTEL1-TNFRSF6B;ENTPD2;PNCK;PDPK2;DQX1;NEK6;ATP10B;ENTPD8;FIGN;IRAK3;MYLK3;HKDC1 |
| 351 | zinc ion binding (GO:0008270) | 2/1256 | 0.9999954 | 1 | 0 | 0 | 0.0760075 | 0.0000003 | ADAMDEC1;CPE |
## Uploading data to Enrichr... Done.
## Querying GO_Molecular_Function_2015... Done.
## Querying GO_Cellular_Component_2015... Done.
## Querying GO_Biological_Process_2015... Done.
## Parsing results... Done.
go_biological %>%
knitr::kable(
format = "html", align = rep("c", ncol(go_biological) + 1),
row.names = TRUE
) %>%
kableExtra::kable_styling() %>%
kableExtra::scroll_box(height = "300px")
| Term | Overlap | P.value | Adjusted.P.value | Old.P.value | Old.Adjusted.P.value | Odds.Ratio | Combined.Score | Genes | |
|---|---|---|---|---|---|---|---|---|---|
| 1 | synaptic transmission (GO:0007268) | 14/434 | 0.0001261 | 0.6546647 | 0 | 0 | 3.2258065 | 28.9629235 | GABBR2;KCNJ6;GRID1;SLC6A13;KCNA3;KCNA4;GRIK1;SLC5A7;NPBWR1;SNCG;ANXA9;GABRD;KCNJ1;KCNK3 |
| 2 | macrophage chemotaxis (GO:0048246) | 3/14 | 0.0003306 | 0.8581617 | 0 | 0 | 21.4285714 | 171.7433537 | CX3CR1;CCL5;SFTPD |
| 3 | negative regulation of viral genome replication (GO:0045071) | 4/40 | 0.0006691 | 1.0000000 | 0 | 0 | 10.0000000 | 73.0963454 | APOBEC3H;CCL5;IFIT1;OASL |
| 4 | sprouting angiogenesis (GO:0002040) | 3/24 | 0.0017077 | 1.0000000 | 0 | 0 | 12.5000000 | 79.6578471 | RAMP2;FLT4;GPR124 |
| 5 | cellular potassium ion transport (GO:0071804) | 6/129 | 0.0019065 | 1.0000000 | 0 | 0 | 4.6511628 | 29.1279537 | KCNJ6;CNGA1;KCNA3;KCNA4;KCNJ1;KCNK3 |
| 6 | potassium ion transmembrane transport (GO:0071805) | 6/129 | 0.0019065 | 1.0000000 | 0 | 0 | 4.6511628 | 29.1279537 | KCNJ6;CNGA1;KCNA3;KCNA4;KCNJ1;KCNK3 |
| 7 | positive regulation of vasodilation (GO:0045909) | 3/26 | 0.0021617 | 1.0000000 | 0 | 0 | 11.5384615 | 70.8100816 | NPPC;GJA1;ALOX12 |
| 8 | regulation of viral genome replication (GO:0045069) | 4/57 | 0.0025341 | 1.0000000 | 0 | 0 | 7.0175439 | 41.9501817 | APOBEC3H;CCL5;IFIT1;OASL |
| 9 | cytidine deamination (GO:0009972) | 2/9 | 0.0034202 | 1.0000000 | 0 | 0 | 22.2222222 | 126.1788209 | APOBEC2;APOBEC3H |
| 10 | cytidine metabolic process (GO:0046087) | 2/9 | 0.0034202 | 1.0000000 | 0 | 0 | 22.2222222 | 126.1788209 | APOBEC2;APOBEC3H |
| 11 | cytidine catabolic process (GO:0006216) | 2/9 | 0.0034202 | 1.0000000 | 0 | 0 | 22.2222222 | 126.1788209 | APOBEC2;APOBEC3H |
| 12 | potassium ion transport (GO:0006813) | 6/151 | 0.0041682 | 1.0000000 | 0 | 0 | 3.9735099 | 21.7758854 | KCNJ6;CNGA1;KCNA3;KCNA4;KCNJ1;KCNK3 |
| 13 | pyrimidine ribonucleoside catabolic process (GO:0046133) | 2/10 | 0.0042472 | 1.0000000 | 0 | 0 | 20.0000000 | 109.2297554 | APOBEC2;APOBEC3H |
| 14 | ethanol oxidation (GO:0006069) | 2/11 | 0.0051570 | 1.0000000 | 0 | 0 | 18.1818182 | 95.7708415 | ADH1C;ADH1B |
| 15 | positive regulation of blood circulation (GO:1903524) | 4/72 | 0.0058778 | 1.0000000 | 0 | 0 | 5.5555556 | 28.5365281 | NPPC;GJA1;OR51E2;ALOX12 |
| 16 | male sex determination (GO:0030238) | 2/12 | 0.0061479 | 1.0000000 | 0 | 0 | 16.6666667 | 84.8608119 | FGF9;DMRT1 |
| 17 | negative regulation of viral process (GO:0048525) | 4/75 | 0.0067856 | 1.0000000 | 0 | 0 | 5.3333333 | 26.6290906 | APOBEC3H;CCL5;IFIT1;OASL |
| 18 | regulation of vasodilation (GO:0042312) | 3/39 | 0.0069091 | 1.0000000 | 0 | 0 | 7.6923077 | 38.2686129 | NPPC;GJA1;ALOX12 |
| 19 | myeloid leukocyte migration (GO:0097529) | 4/76 | 0.0071076 | 1.0000000 | 0 | 0 | 5.2631579 | 26.0346606 | CX3CR1;PLA2G1B;CCL5;SFTPD |
| 20 | ethanol metabolic process (GO:0006067) | 2/14 | 0.0083660 | 1.0000000 | 0 | 0 | 14.2857143 | 68.3368024 | ADH1C;ADH1B |
| 21 | regulation of cellular response to growth factor stimulus (GO:0090287) | 6/176 | 0.0086499 | 1.0000000 | 0 | 0 | 3.4090909 | 16.1939003 | FGF9;HHIP;PEG10;FGF18;FBN1;GPR124 |
| 22 | positive regulation of protein dephosphorylation (GO:0035307) | 2/16 | 0.0108884 | 1.0000000 | 0 | 0 | 12.5000000 | 56.5006873 | DLC1;DUSP26 |
| 23 | adult heart development (GO:0007512) | 2/16 | 0.0108884 | 1.0000000 | 0 | 0 | 12.5000000 | 56.5006873 | GJA1;SCUBE1 |
| 24 | positive regulation of vascular endothelial growth factor receptor signaling pathway (GO:0030949) | 2/16 | 0.0108884 | 1.0000000 | 0 | 0 | 12.5000000 | 56.5006873 | FGF9;FGF18 |
| 25 | negative regulation of multi-organism process (GO:0043901) | 5/133 | 0.0109104 | 1.0000000 | 0 | 0 | 3.7593985 | 16.9851219 | NPPC;APOBEC3H;CCL5;IFIT1;OASL |
| 26 | positive regulation of natural killer cell mediated cytotoxicity (GO:0045954) | 2/18 | 0.0137022 | 1.0000000 | 0 | 0 | 11.1111111 | 47.6688727 | KLRK1;CRTAM |
| 27 | regulation of antigen processing and presentation (GO:0002577) | 2/18 | 0.0137022 | 1.0000000 | 0 | 0 | 11.1111111 | 47.6688727 | HLA-DOA;HLA-DQB2 |
| 28 | positive regulation of viral genome replication (GO:0045070) | 2/18 | 0.0137022 | 1.0000000 | 0 | 0 | 11.1111111 | 47.6688727 | CCL5;IFIT1 |
| 29 | negative regulation of meiotic cell cycle (GO:0051447) | 2/18 | 0.0137022 | 1.0000000 | 0 | 0 | 11.1111111 | 47.6688727 | NPPC;DMRT1 |
| 30 | positive regulation of natural killer cell mediated immunity (GO:0002717) | 2/19 | 0.0152144 | 1.0000000 | 0 | 0 | 10.5263158 | 44.0579974 | KLRK1;CRTAM |
| 31 | monovalent inorganic cation transport (GO:0015672) | 9/384 | 0.0154664 | 1.0000000 | 0 | 0 | 2.3437500 | 9.7712881 | SLC5A7;KCNJ6;KCNA3;SLC4A10;CNGA1;KCNA4;KCNJ1;KCNK3;SLC38A4 |
| 32 | regulation of T cell activation (GO:0050863) | 7/259 | 0.0156398 | 1.0000000 | 0 | 0 | 2.7027027 | 11.2376588 | KLRK1;CCL5;SFTPD;TRAC;SCGB1A1;HLA-DOA;HLA-DQB2 |
| 33 | regulation of protein dephosphorylation (GO:0035304) | 2/20 | 0.0167949 | 1.0000000 | 0 | 0 | 10.0000000 | 40.8668071 | DLC1;DUSP26 |
| 34 | regulation of homotypic cell-cell adhesion (GO:0034110) | 2/20 | 0.0167949 | 1.0000000 | 0 | 0 | 10.0000000 | 40.8668071 | CCL5;ALOX12 |
| 35 | positive regulation of endothelial cell migration (GO:0010595) | 3/55 | 0.0176581 | 1.0000000 | 0 | 0 | 5.4545455 | 22.0176155 | FLT4;ALOX12;GPR124 |
| 36 | leukocyte chemotaxis (GO:0030595) | 4/100 | 0.0180733 | 1.0000000 | 0 | 0 | 4.0000000 | 16.0532734 | CX3CR1;PLA2G1B;CCL5;SFTPD |
| 37 | sex determination (GO:0007530) | 2/22 | 0.0201544 | 1.0000000 | 0 | 0 | 9.0909091 | 35.4939443 | DMRT1;FGF9 |
| 38 | pyrimidine nucleoside catabolic process (GO:0046135) | 2/22 | 0.0201544 | 1.0000000 | 0 | 0 | 9.0909091 | 35.4939443 | APOBEC2;APOBEC3H |
| 39 | regulation of tissue remodeling (GO:0034103) | 3/58 | 0.0203229 | 1.0000000 | 0 | 0 | 5.1724138 | 20.1517517 | MC4R;GJA1;FLT4 |
| 40 | xenobiotic metabolic process (GO:0006805) | 5/156 | 0.0204245 | 1.0000000 | 0 | 0 | 3.2051282 | 12.4712148 | CYP2W1;ADH1C;CYP2A13;ADH1B;CYP2F1 |
| 41 | central nervous system development (GO:0007417) | 4/108 | 0.0232396 | 1.0000000 | 0 | 0 | 3.7037037 | 13.9329471 | ROBO2;DCX;GRIK1;GPR124 |
| 42 | ionotropic glutamate receptor signaling pathway (GO:0035235) | 2/24 | 0.0237689 | 1.0000000 | 0 | 0 | 8.3333333 | 31.1614659 | GRID1;GRIK1 |
| 43 | regulation of natural killer cell mediated immunity (GO:0002715) | 2/24 | 0.0237689 | 1.0000000 | 0 | 0 | 8.3333333 | 31.1614659 | KLRK1;CRTAM |
| 44 | regulation of natural killer cell mediated cytotoxicity (GO:0042269) | 2/24 | 0.0237689 | 1.0000000 | 0 | 0 | 8.3333333 | 31.1614659 | KLRK1;CRTAM |
| 45 | regulation of smoothened signaling pathway (GO:0008589) | 3/63 | 0.0252289 | 1.0000000 | 0 | 0 | 4.7619048 | 17.5226913 | FGF9;HHIP;GPC3 |
| 46 | positive regulation of smoothened signaling pathway (GO:0045880) | 2/25 | 0.0256683 | 1.0000000 | 0 | 0 | 8.0000000 | 29.2999902 | FGF9;GPC3 |
| 47 | cellular response to vascular endothelial growth factor stimulus (GO:0035924) | 2/25 | 0.0256683 | 1.0000000 | 0 | 0 | 8.0000000 | 29.2999902 | RAMP2;FLT4 |
| 48 | regulation of cell activation (GO:0050865) | 9/420 | 0.0258303 | 1.0000000 | 0 | 0 | 2.1428571 | 7.8347273 | KLRK1;CCL5;SFTPD;TRAC;SCGB1A1;ALOX12;BPI;HLA-DOA;HLA-DQB2 |
| 49 | regulation of behavior (GO:0050795) | 5/166 | 0.0258581 | 1.0000000 | 0 | 0 | 3.0120482 | 11.0094280 | ROBO2;MC4R;GJA1;CCL5;GPR124 |
| 50 | leukocyte migration (GO:0050900) | 6/226 | 0.0263877 | 1.0000000 | 0 | 0 | 2.6548673 | 9.6500647 | CX3CR1;PLA2G1B;PROS1;CCL5;SFTPD;JAM2 |
| 51 | heart development (GO:0007507) | 5/167 | 0.0264476 | 1.0000000 | 0 | 0 | 2.9940120 | 10.8760212 | GJA1;RAMP2;SCUBE1;HOPX;FBN1 |
| 52 | regulation of cAMP metabolic process (GO:0030814) | 4/113 | 0.0268800 | 1.0000000 | 0 | 0 | 3.5398230 | 12.8013173 | MC4R;NPPC;GABBR2;RAMP2 |
| 53 | positive regulation of cell adhesion (GO:0045785) | 5/171 | 0.0288909 | 1.0000000 | 0 | 0 | 2.9239766 | 10.3632401 | SMOC2;ECM2;CCL5;ALOX12;DUSP26 |
| 54 | neuron migration (GO:0001764) | 4/116 | 0.0292190 | 1.0000000 | 0 | 0 | 3.4482759 | 12.1825356 | GPM6A;GJA1;DCX;FEZF2 |
| 55 | regulation of cyclic nucleotide biosynthetic process (GO:0030802) | 4/116 | 0.0292190 | 1.0000000 | 0 | 0 | 3.4482759 | 12.1825356 | MC4R;NPPC;GABBR2;RAMP2 |
| 56 | angiogenesis (GO:0001525) | 6/236 | 0.0316653 | 1.0000000 | 0 | 0 | 2.5423729 | 8.7776301 | RAMP2;FGF9;FLT4;FGF18;TBX4;GPR124 |
| 57 | regulation of purine nucleotide biosynthetic process (GO:1900371) | 4/119 | 0.0316752 | 1.0000000 | 0 | 0 | 3.3613445 | 11.6041026 | MC4R;NPPC;GABBR2;RAMP2 |
| 58 | regulation of nucleotide biosynthetic process (GO:0030808) | 4/119 | 0.0316752 | 1.0000000 | 0 | 0 | 3.3613445 | 11.6041026 | MC4R;NPPC;GABBR2;RAMP2 |
| 59 | negative regulation of smoothened signaling pathway (GO:0045879) | 2/28 | 0.0317181 | 1.0000000 | 0 | 0 | 7.1428571 | 24.6490560 | HHIP;GPC3 |
| 60 | regulation of vascular endothelial growth factor receptor signaling pathway (GO:0030947) | 2/28 | 0.0317181 | 1.0000000 | 0 | 0 | 7.1428571 | 24.6490560 | FGF9;FGF18 |
| 61 | adherens junction organization (GO:0034332) | 3/69 | 0.0318810 | 1.0000000 | 0 | 0 | 4.3478261 | 14.9814966 | RAMP2;DLC1;CDH7 |
| 62 | regulation of cardiac muscle cell proliferation (GO:0060043) | 2/29 | 0.0338475 | 1.0000000 | 0 | 0 | 6.8965517 | 23.3509763 | GJA1;FGF9 |
| 63 | anion transport (GO:0006820) | 9/443 | 0.0345974 | 1.0000000 | 0 | 0 | 2.0316027 | 6.8342631 | GJA1;FABP3;PLA2G1B;SLC6A13;SLC7A14;SLC4A10;GABRD;CLCA4;SLC38A4 |
| 64 | adherens junction assembly (GO:0034333) | 2/31 | 0.0382674 | 1.0000000 | 0 | 0 | 6.4516129 | 21.0526212 | RAMP2;DLC1 |
| 65 | T cell costimulation (GO:0031295) | 3/76 | 0.0406839 | 1.0000000 | 0 | 0 | 3.9473684 | 12.6391704 | KLRK1;TRAC;HLA-DQB2 |
| 66 | regulation of smooth muscle cell proliferation (GO:0048660) | 3/77 | 0.0420316 | 1.0000000 | 0 | 0 | 3.8961039 | 12.3480501 | NPPC;CCL5;ALOX12 |
| 67 | lymphocyte costimulation (GO:0031294) | 3/77 | 0.0420316 | 1.0000000 | 0 | 0 | 3.8961039 | 12.3480501 | KLRK1;TRAC;HLA-DQB2 |
| 68 | regulation of leukocyte activation (GO:0002694) | 8/390 | 0.0428832 | 1.0000000 | 0 | 0 | 2.0512821 | 6.4600523 | KLRK1;CCL5;SFTPD;TRAC;SCGB1A1;BPI;HLA-DOA;HLA-DQB2 |
| 69 | neuron recognition (GO:0008038) | 2/33 | 0.0428940 | 1.0000000 | 0 | 0 | 6.0606061 | 19.0849967 | ROBO2;FEZF2 |
| 70 | cyclic purine nucleotide metabolic process (GO:0052652) | 2/33 | 0.0428940 | 1.0000000 | 0 | 0 | 6.0606061 | 19.0849967 | NPPC;RAMP2 |
| 71 | regulation of cyclic nucleotide metabolic process (GO:0030799) | 4/133 | 0.0447024 | 1.0000000 | 0 | 0 | 3.0075188 | 9.3465489 | MC4R;NPPC;GABBR2;RAMP2 |
| 72 | positive regulation of epithelial cell migration (GO:0010634) | 3/79 | 0.0447938 | 1.0000000 | 0 | 0 | 3.7974684 | 11.7937443 | FLT4;ALOX12;GPR124 |
| 73 | regulation of membrane depolarization (GO:0003254) | 2/34 | 0.0452816 | 1.0000000 | 0 | 0 | 5.8823529 | 18.2050300 | GJA1;ALOX12 |
| 74 | cyclic nucleotide biosynthetic process (GO:0009190) | 2/34 | 0.0452816 | 1.0000000 | 0 | 0 | 5.8823529 | 18.2050300 | NPPC;RAMP2 |
| 75 | negative regulation of cell activation (GO:0050866) | 4/135 | 0.0467746 | 1.0000000 | 0 | 0 | 2.9629630 | 9.0738214 | SFTPD;SCGB1A1;ALOX12;BPI |
| 76 | organic anion transport (GO:0015711) | 7/328 | 0.0473149 | 1.0000000 | 0 | 0 | 2.1341463 | 6.5111316 | GJA1;FABP3;PLA2G1B;SLC6A13;SLC7A14;SLC4A10;SLC38A4 |
| 77 | defense response to other organism (GO:0098542) | 7/328 | 0.0473149 | 1.0000000 | 0 | 0 | 2.1341463 | 6.5111316 | APOBEC3H;PLA2G1B;CD207;SFTPD;BPI;IFIT1;OASL |
| 78 | pyrimidine-containing compound catabolic process (GO:0072529) | 2/35 | 0.0477172 | 1.0000000 | 0 | 0 | 5.7142857 | 17.3855107 | APOBEC2;APOBEC3H |
| 79 | regulation of cardiac muscle tissue growth (GO:0055021) | 2/35 | 0.0477172 | 1.0000000 | 0 | 0 | 5.7142857 | 17.3855107 | GJA1;FGF9 |
| 80 | regulation of endocrine process (GO:0044060) | 2/35 | 0.0477172 | 1.0000000 | 0 | 0 | 5.7142857 | 17.3855107 | KISS1;OR51E2 |
| 81 | lung development (GO:0030324) | 3/82 | 0.0491020 | 1.0000000 | 0 | 0 | 3.6585366 | 11.0263036 | FGF18;GPC3;TBX4 |
| 82 | positive regulation of cyclic nucleotide biosynthetic process (GO:0030804) | 3/82 | 0.0491020 | 1.0000000 | 0 | 0 | 3.6585366 | 11.0263036 | MC4R;NPPC;RAMP2 |
| 83 | synaptic transmission, glutamatergic (GO:0035249) | 2/36 | 0.0501995 | 1.0000000 | 0 | 0 | 5.5555556 | 16.6208344 | GRID1;GRIK1 |
| 84 | chemokine-mediated signaling pathway (GO:0070098) | 2/36 | 0.0501995 | 1.0000000 | 0 | 0 | 5.5555556 | 16.6208344 | CX3CR1;CCL5 |
| 85 | positive regulation of purine nucleotide biosynthetic process (GO:1900373) | 3/84 | 0.0520826 | 1.0000000 | 0 | 0 | 3.5714286 | 10.5532996 | MC4R;NPPC;RAMP2 |
| 86 | post-embryonic development (GO:0009791) | 3/84 | 0.0520826 | 1.0000000 | 0 | 0 | 3.5714286 | 10.5532996 | NPPC;SCUBE1;KCNJ1 |
| 87 | positive regulation of nucleotide biosynthetic process (GO:0030810) | 3/84 | 0.0520826 | 1.0000000 | 0 | 0 | 3.5714286 | 10.5532996 | MC4R;NPPC;RAMP2 |
| 88 | positive regulation of dephosphorylation (GO:0035306) | 2/37 | 0.0527275 | 1.0000000 | 0 | 0 | 5.4054054 | 15.9060490 | DLC1;DUSP26 |
| 89 | leukotriene metabolic process (GO:0006691) | 2/37 | 0.0527275 | 1.0000000 | 0 | 0 | 5.4054054 | 15.9060490 | PLA2G1B;ALOX12 |
| 90 | positive regulation of leukocyte mediated cytotoxicity (GO:0001912) | 2/37 | 0.0527275 | 1.0000000 | 0 | 0 | 5.4054054 | 15.9060490 | KLRK1;CRTAM |
| 91 | pyrimidine ribonucleoside metabolic process (GO:0046131) | 2/37 | 0.0527275 | 1.0000000 | 0 | 0 | 5.4054054 | 15.9060490 | APOBEC2;APOBEC3H |
| 92 | sodium ion transport (GO:0006814) | 4/141 | 0.0533069 | 1.0000000 | 0 | 0 | 2.8368794 | 8.3168492 | SLC5A7;SLC4A10;KCNJ1;SLC38A4 |
| 93 | regulation of blood circulation (GO:1903522) | 5/204 | 0.0544706 | 1.0000000 | 0 | 0 | 2.4509804 | 7.1325851 | NPPC;GJA1;OR51E2;ALOX12;HOPX |
| 94 | embryonic limb morphogenesis (GO:0030326) | 3/86 | 0.0551489 | 1.0000000 | 0 | 0 | 3.4883721 | 10.1083208 | FGF9;GPC3;TBX4 |
| 95 | positive regulation of Wnt signaling pathway (GO:0030177) | 3/86 | 0.0551489 | 1.0000000 | 0 | 0 | 3.4883721 | 10.1083208 | FGF9;GPC3;LGR5 |
| 96 | embryonic appendage morphogenesis (GO:0035113) | 3/86 | 0.0551489 | 1.0000000 | 0 | 0 | 3.4883721 | 10.1083208 | FGF9;GPC3;TBX4 |
| 97 | regulation of meiotic cell cycle (GO:0051445) | 2/38 | 0.0552999 | 1.0000000 | 0 | 0 | 5.2631579 | 15.2367633 | NPPC;DMRT1 |
| 98 | lung alveolus development (GO:0048286) | 2/38 | 0.0552999 | 1.0000000 | 0 | 0 | 5.2631579 | 15.2367633 | SFTPD;HOPX |
| 99 | long-chain fatty acid transport (GO:0015909) | 2/38 | 0.0552999 | 1.0000000 | 0 | 0 | 5.2631579 | 15.2367633 | FABP3;PLA2G1B |
| 100 | regulation of multicellular organismal metabolic process (GO:0044246) | 2/39 | 0.0579156 | 1.0000000 | 0 | 0 | 5.1282051 | 14.6090715 | MC4R;MFAP4 |
| 101 | regulation of lymphocyte activation (GO:0051249) | 7/344 | 0.0581823 | 1.0000000 | 0 | 0 | 2.0348837 | 5.7875623 | KLRK1;CCL5;SFTPD;TRAC;SCGB1A1;HLA-DOA;HLA-DQB2 |
| 102 | cellular response to interferon-gamma (GO:0071346) | 3/88 | 0.0582996 | 1.0000000 | 0 | 0 | 3.4090909 | 9.6891797 | CCL5;HLA-DQB2;OASL |
| 103 | phototransduction, visible light (GO:0007603) | 3/89 | 0.0599063 | 1.0000000 | 0 | 0 | 3.3707865 | 9.4886736 | OPN1SW;CNGA1;GPC3 |
| 104 | defense response to virus (GO:0051607) | 4/147 | 0.0603096 | 1.0000000 | 0 | 0 | 2.7210884 | 7.6415355 | APOBEC3H;CD207;IFIT1;OASL |
| 105 | telencephalon cell migration (GO:0022029) | 2/40 | 0.0605735 | 1.0000000 | 0 | 0 | 5.0000000 | 14.0194887 | CX3CR1;FEZF2 |
| 106 | regulation of bone remodeling (GO:0046850) | 2/40 | 0.0605735 | 1.0000000 | 0 | 0 | 5.0000000 | 14.0194887 | MC4R;GJA1 |
| 107 | glutamate receptor signaling pathway (GO:0007215) | 2/40 | 0.0605735 | 1.0000000 | 0 | 0 | 5.0000000 | 14.0194887 | GRID1;GRIK1 |
| 108 | positive regulation of cyclic nucleotide metabolic process (GO:0030801) | 3/91 | 0.0631816 | 1.0000000 | 0 | 0 | 3.2967033 | 9.1046463 | MC4R;NPPC;RAMP2 |
| 109 | chondrocyte differentiation (GO:0002062) | 2/41 | 0.0632725 | 1.0000000 | 0 | 0 | 4.8780488 | 13.4648969 | NPPC;FGF9 |
| 110 | primary alcohol metabolic process (GO:0034308) | 2/41 | 0.0632725 | 1.0000000 | 0 | 0 | 4.8780488 | 13.4648969 | ADH1C;ADH1B |
| 111 | negative regulation of behavior (GO:0048521) | 2/41 | 0.0632725 | 1.0000000 | 0 | 0 | 4.8780488 | 13.4648969 | ROBO2;MC4R |
| 112 | regulation of heart growth (GO:0060420) | 2/41 | 0.0632725 | 1.0000000 | 0 | 0 | 4.8780488 | 13.4648969 | GJA1;FGF9 |
| 113 | chloride transport (GO:0006821) | 3/92 | 0.0648498 | 1.0000000 | 0 | 0 | 3.2608696 | 8.9207002 | SLC4A10;GABRD;CLCA4 |
| 114 | regulation of endothelial cell migration (GO:0010594) | 3/92 | 0.0648498 | 1.0000000 | 0 | 0 | 3.2608696 | 8.9207002 | FLT4;ALOX12;GPR124 |
| 115 | response to drug (GO:0042493) | 7/354 | 0.0656994 | 1.0000000 | 0 | 0 | 1.9774011 | 5.3838006 | NPPC;FABP3;DDC;SCGB1A1;SNCG;KCNK3;ABCG2 |
| 116 | icosanoid biosynthetic process (GO:0046456) | 2/42 | 0.0660116 | 1.0000000 | 0 | 0 | 4.7619048 | 12.9424984 | PLA2G1B;ALOX12 |
| 117 | negative regulation of T cell proliferation (GO:0042130) | 2/42 | 0.0660116 | 1.0000000 | 0 | 0 | 4.7619048 | 12.9424984 | SFTPD;SCGB1A1 |
| 118 | fatty acid derivative biosynthetic process (GO:1901570) | 2/42 | 0.0660116 | 1.0000000 | 0 | 0 | 4.7619048 | 12.9424984 | PLA2G1B;ALOX12 |
| 119 | positive regulation of cell killing (GO:0031343) | 2/42 | 0.0660116 | 1.0000000 | 0 | 0 | 4.7619048 | 12.9424984 | KLRK1;CRTAM |
| 120 | regulation of viral process (GO:0050792) | 4/152 | 0.0665001 | 1.0000000 | 0 | 0 | 2.6315789 | 7.1330304 | APOBEC3H;CCL5;IFIT1;OASL |
| 121 | forebrain cell migration (GO:0021885) | 2/43 | 0.0687896 | 1.0000000 | 0 | 0 | 4.6511628 | 12.4497769 | CX3CR1;FEZF2 |
| 122 | negative regulation of blood coagulation (GO:0030195) | 2/43 | 0.0687896 | 1.0000000 | 0 | 0 | 4.6511628 | 12.4497769 | PROS1;ALOX12 |
| 123 | negative regulation of hemostasis (GO:1900047) | 2/43 | 0.0687896 | 1.0000000 | 0 | 0 | 4.6511628 | 12.4497769 | PROS1;ALOX12 |
| 124 | cell chemotaxis (GO:0060326) | 4/155 | 0.0703673 | 1.0000000 | 0 | 0 | 2.5806452 | 6.8491008 | CX3CR1;PLA2G1B;CCL5;SFTPD |
| 125 | regulation of leukocyte mediated cytotoxicity (GO:0001910) | 2/44 | 0.0716056 | 1.0000000 | 0 | 0 | 4.5454545 | 11.9844629 | KLRK1;CRTAM |
| 126 | carboxylic acid transport (GO:0046942) | 5/224 | 0.0747953 | 1.0000000 | 0 | 0 | 2.2321429 | 5.7879457 | FABP3;PLA2G1B;SLC6A13;SLC7A14;SLC38A4 |
| 127 | regulation of cAMP biosynthetic process (GO:0030817) | 3/98 | 0.0752775 | 1.0000000 | 0 | 0 | 3.0612245 | 7.9180831 | MC4R;GABBR2;RAMP2 |
| 128 | protein oligomerization (GO:0051259) | 7/366 | 0.0754631 | 1.0000000 | 0 | 0 | 1.9125683 | 4.9422889 | GJA1;SCUBE1;CCL5;QPRT;KCNA3;KCNA4;TGM3 |
| 129 | organic acid transport (GO:0015849) | 5/226 | 0.0770271 | 1.0000000 | 0 | 0 | 2.2123894 | 5.6716780 | FABP3;PLA2G1B;SLC6A13;SLC7A14;SLC38A4 |
| 130 | cell junction assembly (GO:0034329) | 4/160 | 0.0770636 | 1.0000000 | 0 | 0 | 2.5000000 | 6.4078112 | GJA1;RAMP2;DLC1;CDH7 |
| 131 | T cell receptor signaling pathway (GO:0050852) | 3/99 | 0.0770836 | 1.0000000 | 0 | 0 | 3.0303030 | 7.7662575 | TRAC;SKAP1;HLA-DQB2 |
| 132 | positive regulation of male gonad development (GO:2000020) | 1/8 | 0.0772681 | 1.0000000 | 0 | 0 | 12.5000000 | 32.0059307 | DMRT1 |
| 133 | activated T cell proliferation (GO:0050798) | 1/8 | 0.0772681 | 1.0000000 | 0 | 0 | 12.5000000 | 32.0059307 | CRTAM |
| 134 | purine ribonucleotide transport (GO:0015868) | 1/8 | 0.0772681 | 1.0000000 | 0 | 0 | 12.5000000 | 32.0059307 | GJA1 |
| 135 | endothelium development (GO:0003158) | 1/8 | 0.0772681 | 1.0000000 | 0 | 0 | 12.5000000 | 32.0059307 | GJA1 |
| 136 | negative regulation of cytosolic calcium ion concentration (GO:0051481) | 1/8 | 0.0772681 | 1.0000000 | 0 | 0 | 12.5000000 | 32.0059307 | KCNK3 |
| 137 | regulation of vascular endothelial growth factor signaling pathway (GO:1900746) | 1/8 | 0.0772681 | 1.0000000 | 0 | 0 | 12.5000000 | 32.0059307 | GPR124 |
| 138 | sequestering of extracellular ligand from receptor (GO:0035581) | 1/8 | 0.0772681 | 1.0000000 | 0 | 0 | 12.5000000 | 32.0059307 | FBN1 |
| 139 | embryonic process involved in female pregnancy (GO:0060136) | 1/8 | 0.0772681 | 1.0000000 | 0 | 0 | 12.5000000 | 32.0059307 | ABCG2 |
| 140 | cell proliferation involved in metanephros development (GO:0072203) | 1/8 | 0.0772681 | 1.0000000 | 0 | 0 | 12.5000000 | 32.0059307 | GPC3 |
| 141 | regulation of chemokine-mediated signaling pathway (GO:0070099) | 1/8 | 0.0772681 | 1.0000000 | 0 | 0 | 12.5000000 | 32.0059307 | CCL5 |
| 142 | regulation of antigen processing and presentation of peptide antigen (GO:0002583) | 1/8 | 0.0772681 | 1.0000000 | 0 | 0 | 12.5000000 | 32.0059307 | HLA-DOA |
| 143 | regulation of atrial cardiac muscle cell membrane depolarization (GO:0060371) | 1/8 | 0.0772681 | 1.0000000 | 0 | 0 | 12.5000000 | 32.0059307 | GJA1 |
| 144 | adenine nucleotide transport (GO:0051503) | 1/8 | 0.0772681 | 1.0000000 | 0 | 0 | 12.5000000 | 32.0059307 | GJA1 |
| 145 | substrate-independent telencephalic tangential migration (GO:0021826) | 1/8 | 0.0772681 | 1.0000000 | 0 | 0 | 12.5000000 | 32.0059307 | FEZF2 |
| 146 | positive regulation of protein kinase C signaling (GO:0090037) | 1/8 | 0.0772681 | 1.0000000 | 0 | 0 | 12.5000000 | 32.0059307 | FLT4 |
| 147 | regulation of meiosis I (GO:0060631) | 1/8 | 0.0772681 | 1.0000000 | 0 | 0 | 12.5000000 | 32.0059307 | DMRT1 |
| 148 | positive regulation of growth hormone secretion (GO:0060124) | 1/8 | 0.0772681 | 1.0000000 | 0 | 0 | 12.5000000 | 32.0059307 | KISS1 |
| 149 | regulation of activation of Janus kinase activity (GO:0010533) | 1/8 | 0.0772681 | 1.0000000 | 0 | 0 | 12.5000000 | 32.0059307 | CCL5 |
| 150 | cellular response to exogenous dsRNA (GO:0071360) | 1/8 | 0.0772681 | 1.0000000 | 0 | 0 | 12.5000000 | 32.0059307 | IFIT1 |
| 151 | response to xenobiotic stimulus (GO:0009410) | 1/8 | 0.0772681 | 1.0000000 | 0 | 0 | 12.5000000 | 32.0059307 | SCGB1A1 |
| 152 | citrulline biosynthetic process (GO:0019240) | 1/8 | 0.0772681 | 1.0000000 | 0 | 0 | 12.5000000 | 32.0059307 | PADI3 |
| 153 | substrate-independent telencephalic tangential interneuron migration (GO:0021843) | 1/8 | 0.0772681 | 1.0000000 | 0 | 0 | 12.5000000 | 32.0059307 | FEZF2 |
| 154 | gap junction assembly (GO:0016264) | 1/8 | 0.0772681 | 1.0000000 | 0 | 0 | 12.5000000 | 32.0059307 | GJA1 |
| 155 | positive regulation of immune response to tumor cell (GO:0002839) | 1/8 | 0.0772681 | 1.0000000 | 0 | 0 | 12.5000000 | 32.0059307 | CRTAM |
| 156 | regulation of response to tumor cell (GO:0002834) | 1/8 | 0.0772681 | 1.0000000 | 0 | 0 | 12.5000000 | 32.0059307 | CRTAM |
| 157 | regulation of immune response to tumor cell (GO:0002837) | 1/8 | 0.0772681 | 1.0000000 | 0 | 0 | 12.5000000 | 32.0059307 | CRTAM |
| 158 | positive regulation of response to tumor cell (GO:0002836) | 1/8 | 0.0772681 | 1.0000000 | 0 | 0 | 12.5000000 | 32.0059307 | CRTAM |
| 159 | regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:0045091) | 1/8 | 0.0772681 | 1.0000000 | 0 | 0 | 12.5000000 | 32.0059307 | APOBEC3H |
| 160 | positive regulation of muscle organ development (GO:0048636) | 2/46 | 0.0773472 | 1.0000000 | 0 | 0 | 4.3478261 | 11.1280460 | GJA1;FGF9 |
| 161 | positive regulation of striated muscle tissue development (GO:0045844) | 2/46 | 0.0773472 | 1.0000000 | 0 | 0 | 4.3478261 | 11.1280460 | GJA1;FGF9 |
| 162 | positive regulation of smooth muscle cell proliferation (GO:0048661) | 2/46 | 0.0773472 | 1.0000000 | 0 | 0 | 4.3478261 | 11.1280460 | CCL5;ALOX12 |
| 163 | amino acid transmembrane transport (GO:0003333) | 2/46 | 0.0773472 | 1.0000000 | 0 | 0 | 4.3478261 | 11.1280460 | SLC7A14;SLC38A4 |
| 164 | cell-cell junction organization (GO:0045216) | 4/161 | 0.0784400 | 1.0000000 | 0 | 0 | 2.4844720 | 6.3240267 | GJA1;RAMP2;DLC1;CDH7 |
| 165 | negative regulation of coagulation (GO:0050819) | 2/47 | 0.0802709 | 1.0000000 | 0 | 0 | 4.2553191 | 10.7333979 | PROS1;ALOX12 |
| 166 | keratinization (GO:0031424) | 2/47 | 0.0802709 | 1.0000000 | 0 | 0 | 4.2553191 | 10.7333979 | CNFN;TGM3 |
| 167 | positive regulation of muscle tissue development (GO:1901863) | 2/47 | 0.0802709 | 1.0000000 | 0 | 0 | 4.2553191 | 10.7333979 | GJA1;FGF9 |
| 168 | positive regulation of angiogenesis (GO:0045766) | 3/101 | 0.0807525 | 1.0000000 | 0 | 0 | 2.9702970 | 7.4743550 | CX3CR1;RAMP2;ALOX12 |
| 169 | limb morphogenesis (GO:0035108) | 3/101 | 0.0807525 | 1.0000000 | 0 | 0 | 2.9702970 | 7.4743550 | FGF9;GPC3;TBX4 |
| 170 | appendage morphogenesis (GO:0035107) | 3/101 | 0.0807525 | 1.0000000 | 0 | 0 | 2.9702970 | 7.4743550 | FGF9;GPC3;TBX4 |
| 171 | regulation of cardiac muscle tissue development (GO:0055024) | 2/48 | 0.0832284 | 1.0000000 | 0 | 0 | 4.1666667 | 10.3590263 | GJA1;FGF9 |
| 172 | stem cell proliferation (GO:0072089) | 2/48 | 0.0832284 | 1.0000000 | 0 | 0 | 4.1666667 | 10.3590263 | HHIP;GPC3 |
| 173 | fatty acid transport (GO:0015908) | 2/49 | 0.0862189 | 1.0000000 | 0 | 0 | 4.0816327 | 10.0035323 | FABP3;PLA2G1B |
| 174 | monocarboxylic acid transport (GO:0015718) | 3/104 | 0.0863951 | 1.0000000 | 0 | 0 | 2.8846154 | 7.0639147 | FABP3;PLA2G1B;SLC6A13 |
| 175 | detection of visible light (GO:0009584) | 3/104 | 0.0863951 | 1.0000000 | 0 | 0 | 2.8846154 | 7.0639147 | OPN1SW;CNGA1;GPC3 |
| 176 | negative regulation of cellular response to growth factor stimulus (GO:0090288) | 3/104 | 0.0863951 | 1.0000000 | 0 | 0 | 2.8846154 | 7.0639147 | PEG10;FBN1;GPR124 |
| 177 | gamma-aminobutyric acid transport (GO:0015812) | 1/9 | 0.0864991 | 1.0000000 | 0 | 0 | 11.1111111 | 27.1957962 | SLC6A13 |
| 178 | regulation of chronic inflammatory response (GO:0002676) | 1/9 | 0.0864991 | 1.0000000 | 0 | 0 | 11.1111111 | 27.1957962 | CCL5 |
| 179 | heme transport (GO:0015886) | 1/9 | 0.0864991 | 1.0000000 | 0 | 0 | 11.1111111 | 27.1957962 | ABCG2 |
| 180 | regulation of gonadotropin secretion (GO:0032276) | 1/9 | 0.0864991 | 1.0000000 | 0 | 0 | 11.1111111 | 27.1957962 | KISS1 |
| 181 | alkaloid metabolic process (GO:0009820) | 1/9 | 0.0864991 | 1.0000000 | 0 | 0 | 11.1111111 | 27.1957962 | DDC |
| 182 | lymph vessel development (GO:0001945) | 1/9 | 0.0864991 | 1.0000000 | 0 | 0 | 11.1111111 | 27.1957962 | FLT4 |
| 183 | regulation of helicase activity (GO:0051095) | 1/9 | 0.0864991 | 1.0000000 | 0 | 0 | 11.1111111 | 27.1957962 | IFIT1 |
| 184 | regulation of cellular response to vascular endothelial growth factor stimulus (GO:1902547) | 1/9 | 0.0864991 | 1.0000000 | 0 | 0 | 11.1111111 | 27.1957962 | GPR124 |
| 185 | negative regulation of homotypic cell-cell adhesion (GO:0034111) | 1/9 | 0.0864991 | 1.0000000 | 0 | 0 | 11.1111111 | 27.1957962 | ALOX12 |
| 186 | regulation of phospholipase A2 activity (GO:0032429) | 1/9 | 0.0864991 | 1.0000000 | 0 | 0 | 11.1111111 | 27.1957962 | PLA2G1B |
| 187 | atrial cardiac muscle cell action potential (GO:0086014) | 1/9 | 0.0864991 | 1.0000000 | 0 | 0 | 11.1111111 | 27.1957962 | GJA1 |
| 188 | DNA deamination (GO:0045006) | 1/9 | 0.0864991 | 1.0000000 | 0 | 0 | 11.1111111 | 27.1957962 | APOBEC3H |
| 189 | response to pheromone (GO:0019236) | 1/9 | 0.0864991 | 1.0000000 | 0 | 0 | 11.1111111 | 27.1957962 | TMEM145 |
| 190 | opioid receptor signaling pathway (GO:0038003) | 1/9 | 0.0864991 | 1.0000000 | 0 | 0 | 11.1111111 | 27.1957962 | NPBWR1 |
| 191 | positive regulation of amino acid transport (GO:0051957) | 1/9 | 0.0864991 | 1.0000000 | 0 | 0 | 11.1111111 | 27.1957962 | GRIK1 |
| 192 | eosinophil chemotaxis (GO:0048245) | 1/9 | 0.0864991 | 1.0000000 | 0 | 0 | 11.1111111 | 27.1957962 | CCL5 |
| 193 | regulation of multi-organism process (GO:0043900) | 6/306 | 0.0874918 | 1.0000000 | 0 | 0 | 1.9607843 | 4.7768817 | NPPC;CD8B;APOBEC3H;CCL5;IFIT1;OASL |
| 194 | response to fatty acid (GO:0070542) | 2/50 | 0.0892415 | 1.0000000 | 0 | 0 | 4.0000000 | 9.6656385 | FABP3;OR51E2 |
| 195 | negative regulation of wound healing (GO:0061045) | 2/50 | 0.0892415 | 1.0000000 | 0 | 0 | 4.0000000 | 9.6656385 | PROS1;ALOX12 |
| 196 | regulation of cell killing (GO:0031341) | 2/50 | 0.0892415 | 1.0000000 | 0 | 0 | 4.0000000 | 9.6656385 | KLRK1;CRTAM |
| 197 | positive regulation of protein secretion (GO:0050714) | 3/106 | 0.0902475 | 1.0000000 | 0 | 0 | 2.8301887 | 6.8071667 | PLA2G1B;CRTAM;OR51E2 |
| 198 | cell growth (GO:0016049) | 3/106 | 0.0902475 | 1.0000000 | 0 | 0 | 2.8301887 | 6.8071667 | NDRG4;DCX;EMP1 |
| 199 | regulation of wound healing (GO:0061041) | 3/107 | 0.0922004 | 1.0000000 | 0 | 0 | 2.8037383 | 6.6835268 | PROS1;ALOX12;HOPX |
| 200 | regulation of response to biotic stimulus (GO:0002831) | 3/107 | 0.0922004 | 1.0000000 | 0 | 0 | 2.8037383 | 6.6835268 | CD8B;CRTAM;IFIT1 |
| 201 | unsaturated fatty acid biosynthetic process (GO:0006636) | 2/51 | 0.0922950 | 1.0000000 | 0 | 0 | 3.9215686 | 9.3441758 | PLA2G1B;ALOX12 |
| 202 | negative regulation of immune system process (GO:0002683) | 6/311 | 0.0927754 | 1.0000000 | 0 | 0 | 1.9292605 | 4.5869588 | SFTPD;SCGB1A1;BPI;UBASH3A;IFIT1;HLA-DOA |
| 203 | response to other organism (GO:0051707) | 8/462 | 0.0932984 | 1.0000000 | 0 | 0 | 1.7316017 | 4.1072776 | APOBEC3H;PLA2G1B;CCL5;CD207;SFTPD;BPI;IFIT1;OASL |
| 204 | response to interferon-gamma (GO:0034341) | 3/108 | 0.0941707 | 1.0000000 | 0 | 0 | 2.7777778 | 6.5629070 | CCL5;HLA-DQB2;OASL |
| 205 | anion transmembrane transport (GO:0098656) | 4/172 | 0.0943786 | 1.0000000 | 0 | 0 | 2.3255814 | 5.4893965 | SLC7A14;GABRD;CLCA4;SLC38A4 |
| 206 | nitrogen compound transport (GO:0071705) | 8/464 | 0.0950459 | 1.0000000 | 0 | 0 | 1.7241379 | 4.0575780 | MC4R;SLC5A7;GJA1;DDC;SLC6A13;SLC7A14;ABCG2;SLC38A4 |
| 207 | negative regulation of stress fiber assembly (GO:0051497) | 1/10 | 0.0956382 | 1.0000000 | 0 | 0 | 10.0000000 | 23.4718325 | DLC1 |
| 208 | regulation of glomerular filtration (GO:0003093) | 1/10 | 0.0956382 | 1.0000000 | 0 | 0 | 10.0000000 | 23.4718325 | GJA1 |
| 209 | regulation of T cell chemotaxis (GO:0010819) | 1/10 | 0.0956382 | 1.0000000 | 0 | 0 | 10.0000000 | 23.4718325 | CCL5 |
| 210 | regulation of macrophage chemotaxis (GO:0010758) | 1/10 | 0.0956382 | 1.0000000 | 0 | 0 | 10.0000000 | 23.4718325 | CCL5 |
| 211 | positive regulation of T cell chemotaxis (GO:0010820) | 1/10 | 0.0956382 | 1.0000000 | 0 | 0 | 10.0000000 | 23.4718325 | CCL5 |
| 212 | cardiovascular system development (GO:0072358) | 1/10 | 0.0956382 | 1.0000000 | 0 | 0 | 10.0000000 | 23.4718325 | KCNJ1 |
| 213 | surfactant homeostasis (GO:0043129) | 1/10 | 0.0956382 | 1.0000000 | 0 | 0 | 10.0000000 | 23.4718325 | SFTPD |
| 214 | aggressive behavior (GO:0002118) | 1/10 | 0.0956382 | 1.0000000 | 0 | 0 | 10.0000000 | 23.4718325 | SNCG |
| 215 | negative regulation of cardiac muscle tissue growth (GO:0055022) | 1/10 | 0.0956382 | 1.0000000 | 0 | 0 | 10.0000000 | 23.4718325 | GJA1 |
| 216 | purine nucleotide transport (GO:0015865) | 1/10 | 0.0956382 | 1.0000000 | 0 | 0 | 10.0000000 | 23.4718325 | GJA1 |
| 217 | positive regulation of endothelial cell differentiation (GO:0045603) | 1/10 | 0.0956382 | 1.0000000 | 0 | 0 | 10.0000000 | 23.4718325 | ALOX12 |
| 218 | regulation of tight junction assembly (GO:2000810) | 1/10 | 0.0956382 | 1.0000000 | 0 | 0 | 10.0000000 | 23.4718325 | GJA1 |
| 219 | negative regulation of gluconeogenesis (GO:0045721) | 1/10 | 0.0956382 | 1.0000000 | 0 | 0 | 10.0000000 | 23.4718325 | LEPR |
| 220 | phospholipid homeostasis (GO:0055091) | 1/10 | 0.0956382 | 1.0000000 | 0 | 0 | 10.0000000 | 23.4718325 | FABP3 |
| 221 | negative regulation of synaptic transmission, glutamatergic (GO:0051967) | 1/10 | 0.0956382 | 1.0000000 | 0 | 0 | 10.0000000 | 23.4718325 | GRIK1 |
| 222 | response to insecticide (GO:0017085) | 1/10 | 0.0956382 | 1.0000000 | 0 | 0 | 10.0000000 | 23.4718325 | DDC |
| 223 | positive regulation of vasculogenesis (GO:2001214) | 1/10 | 0.0956382 | 1.0000000 | 0 | 0 | 10.0000000 | 23.4718325 | RAMP2 |
| 224 | regulation of male gonad development (GO:2000018) | 1/10 | 0.0956382 | 1.0000000 | 0 | 0 | 10.0000000 | 23.4718325 | DMRT1 |
| 225 | eosinophil migration (GO:0072677) | 1/10 | 0.0956382 | 1.0000000 | 0 | 0 | 10.0000000 | 23.4718325 | CCL5 |
| 226 | positive regulation of monocyte chemotaxis (GO:0090026) | 1/10 | 0.0956382 | 1.0000000 | 0 | 0 | 10.0000000 | 23.4718325 | CCL5 |
| 227 | regulation of mononuclear cell migration (GO:0071675) | 1/10 | 0.0956382 | 1.0000000 | 0 | 0 | 10.0000000 | 23.4718325 | CCL5 |
| 228 | regulation of phospholipid biosynthetic process (GO:0071071) | 1/10 | 0.0956382 | 1.0000000 | 0 | 0 | 10.0000000 | 23.4718325 | FABP3 |
| 229 | negative regulation of heart growth (GO:0061117) | 1/10 | 0.0956382 | 1.0000000 | 0 | 0 | 10.0000000 | 23.4718325 | GJA1 |
| 230 | lymphangiogenesis (GO:0001946) | 1/10 | 0.0956382 | 1.0000000 | 0 | 0 | 10.0000000 | 23.4718325 | FLT4 |
| 231 | resolution of meiotic recombination intermediates (GO:0000712) | 1/10 | 0.0956382 | 1.0000000 | 0 | 0 | 10.0000000 | 23.4718325 | MEIOB |
| 232 | long-chain fatty acid biosynthetic process (GO:0042759) | 1/10 | 0.0956382 | 1.0000000 | 0 | 0 | 10.0000000 | 23.4718325 | ALOX12 |
| 233 | regulation of ion transmembrane transport (GO:0034765) | 6/314 | 0.0960269 | 1.0000000 | 0 | 0 | 1.9108280 | 4.4773126 | GJA1;KCNJ6;KCNA3;KCNA4;KCNJ1;KCNK3 |
| 234 | phototransduction (GO:0007602) | 3/109 | 0.0961583 | 1.0000000 | 0 | 0 | 2.7522936 | 6.4452104 | OPN1SW;CNGA1;GPC3 |
| 235 | cell recognition (GO:0008037) | 3/109 | 0.0961583 | 1.0000000 | 0 | 0 | 2.7522936 | 6.4452104 | ROBO2;CRTAM;FEZF2 |
| 236 | regulation of symbiosis, encompassing mutualism through parasitism (GO:0043903) | 4/174 | 0.0974299 | 1.0000000 | 0 | 0 | 2.2988506 | 5.3531543 | APOBEC3H;CCL5;IFIT1;OASL |
| 237 | negative regulation of lymphocyte proliferation (GO:0050672) | 2/53 | 0.0984918 | 1.0000000 | 0 | 0 | 3.7735849 | 8.7463472 | SFTPD;SCGB1A1 |
| 238 | negative regulation of mononuclear cell proliferation (GO:0032945) | 2/53 | 0.0984918 | 1.0000000 | 0 | 0 | 3.7735849 | 8.7463472 | SFTPD;SCGB1A1 |
| 239 | granulocyte chemotaxis (GO:0071621) | 2/53 | 0.0984918 | 1.0000000 | 0 | 0 | 3.7735849 | 8.7463472 | PLA2G1B;CCL5 |
| 240 | fatty acid biosynthetic process (GO:0006633) | 3/111 | 0.1001846 | 1.0000000 | 0 | 0 | 2.7027027 | 6.2182191 | CH25H;PLA2G1B;ALOX12 |
| 241 | cytosolic calcium ion homeostasis (GO:0051480) | 4/176 | 0.1005270 | 1.0000000 | 0 | 0 | 2.2727273 | 5.2212019 | KISS1;CD52;GJA1;KCNK3 |
| 242 | response to insulin (GO:0032868) | 5/246 | 0.1012805 | 1.0000000 | 0 | 0 | 2.0325203 | 4.6541895 | MC4R;FABP3;FGF9;PLA2G1B;FGF18 |
| 243 | pyrimidine nucleoside metabolic process (GO:0006213) | 2/54 | 0.1016332 | 1.0000000 | 0 | 0 | 3.7037037 | 8.4680937 | APOBEC2;APOBEC3H |
| 244 | negative regulation of vascular permeability (GO:0043116) | 1/11 | 0.1046863 | 1.0000000 | 0 | 0 | 9.0909091 | 20.5162457 | RAMP2 |
| 245 | negative regulation of meiosis (GO:0045835) | 1/11 | 0.1046863 | 1.0000000 | 0 | 0 | 9.0909091 | 20.5162457 | DMRT1 |
| 246 | regulation of timing of cell differentiation (GO:0048505) | 1/11 | 0.1046863 | 1.0000000 | 0 | 0 | 9.0909091 | 20.5162457 | FGF9 |
| 247 | receptor guanylyl cyclase signaling pathway (GO:0007168) | 1/11 | 0.1046863 | 1.0000000 | 0 | 0 | 9.0909091 | 20.5162457 | NPPC |
| 248 | negative regulation of Rho protein signal transduction (GO:0035024) | 1/11 | 0.1046863 | 1.0000000 | 0 | 0 | 9.0909091 | 20.5162457 | DLC1 |
| 249 | dopamine biosynthetic process (GO:0042416) | 1/11 | 0.1046863 | 1.0000000 | 0 | 0 | 9.0909091 | 20.5162457 | DDC |
| 250 | nephron epithelium morphogenesis (GO:0072088) | 1/11 | 0.1046863 | 1.0000000 | 0 | 0 | 9.0909091 | 20.5162457 | GPC3 |
| 251 | nephron tubule morphogenesis (GO:0072078) | 1/11 | 0.1046863 | 1.0000000 | 0 | 0 | 9.0909091 | 20.5162457 | GPC3 |
| 252 | regulation of growth hormone secretion (GO:0060123) | 1/11 | 0.1046863 | 1.0000000 | 0 | 0 | 9.0909091 | 20.5162457 | KISS1 |
| 253 | lung-associated mesenchyme development (GO:0060484) | 1/11 | 0.1046863 | 1.0000000 | 0 | 0 | 9.0909091 | 20.5162457 | FGF9 |
| 254 | regulation of Wnt signaling pathway, planar cell polarity pathway (GO:2000095) | 1/11 | 0.1046863 | 1.0000000 | 0 | 0 | 9.0909091 | 20.5162457 | GPC3 |
| 255 | germ cell migration (GO:0008354) | 1/11 | 0.1046863 | 1.0000000 | 0 | 0 | 9.0909091 | 20.5162457 | DMRT1 |
| 256 | response to folic acid (GO:0051593) | 1/11 | 0.1046863 | 1.0000000 | 0 | 0 | 9.0909091 | 20.5162457 | ABCG2 |
| 257 | serotonin metabolic process (GO:0042428) | 1/11 | 0.1046863 | 1.0000000 | 0 | 0 | 9.0909091 | 20.5162457 | DDC |
| 258 | cell proliferation involved in kidney development (GO:0072111) | 1/11 | 0.1046863 | 1.0000000 | 0 | 0 | 9.0909091 | 20.5162457 | GPC3 |
| 259 | mRNA modification (GO:0016556) | 1/11 | 0.1046863 | 1.0000000 | 0 | 0 | 9.0909091 | 20.5162457 | APOBEC2 |
| 260 | skeletal muscle tissue regeneration (GO:0043403) | 1/11 | 0.1046863 | 1.0000000 | 0 | 0 | 9.0909091 | 20.5162457 | GJA1 |
| 261 | basement membrane organization (GO:0071711) | 1/11 | 0.1046863 | 1.0000000 | 0 | 0 | 9.0909091 | 20.5162457 | RAMP2 |
| 262 | granulocyte migration (GO:0097530) | 2/55 | 0.1048020 | 1.0000000 | 0 | 0 | 3.6363636 | 8.2024799 | PLA2G1B;CCL5 |
| 263 | regulation of angiogenesis (GO:0045765) | 4/179 | 0.1052574 | 1.0000000 | 0 | 0 | 2.2346369 | 5.0309424 | CX3CR1;RAMP2;ALOX12;GPR124 |
| 264 | neuropeptide signaling pathway (GO:0007218) | 3/114 | 0.1063488 | 1.0000000 | 0 | 0 | 2.6315789 | 5.8974502 | NPBWR1;SCG5;GPR124 |
| 265 | response to virus (GO:0009615) | 5/250 | 0.1065424 | 1.0000000 | 0 | 0 | 2.0000000 | 4.4784239 | APOBEC3H;CCL5;CD207;IFIT1;OASL |
| 266 | negative regulation of leukocyte proliferation (GO:0070664) | 2/56 | 0.1079976 | 1.0000000 | 0 | 0 | 3.5714286 | 7.9487379 | SFTPD;SCGB1A1 |
| 267 | regulation of transmembrane transport (GO:0034762) | 6/327 | 0.1108102 | 1.0000000 | 0 | 0 | 1.8348624 | 4.0365800 | GJA1;KCNJ6;KCNA3;KCNA4;KCNJ1;KCNK3 |
| 268 | neurotransmitter secretion (GO:0007269) | 2/57 | 0.1112189 | 1.0000000 | 0 | 0 | 3.5087719 | 7.7061583 | SLC5A7;SLC6A13 |
| 269 | UV protection (GO:0009650) | 1/12 | 0.1136443 | 1.0000000 | 0 | 0 | 8.3333333 | 18.1223455 | MFAP4 |
| 270 | microglial cell activation (GO:0001774) | 1/12 | 0.1136443 | 1.0000000 | 0 | 0 | 8.3333333 | 18.1223455 | CX3CR1 |
| 271 | extracellular fibril organization (GO:0043206) | 1/12 | 0.1136443 | 1.0000000 | 0 | 0 | 8.3333333 | 18.1223455 | MFAP4 |
| 272 | chemical homeostasis within a tissue (GO:0048875) | 1/12 | 0.1136443 | 1.0000000 | 0 | 0 | 8.3333333 | 18.1223455 | SFTPD |
| 273 | peptidyl-glutamic acid carboxylation (GO:0017187) | 1/12 | 0.1136443 | 1.0000000 | 0 | 0 | 8.3333333 | 18.1223455 | PROS1 |
| 274 | regulation of ventricular cardiac muscle cell membrane repolarization (GO:0060307) | 1/12 | 0.1136443 | 1.0000000 | 0 | 0 | 8.3333333 | 18.1223455 | GJA1 |
| 275 | regulation of interleukin-13 production (GO:0032656) | 1/12 | 0.1136443 | 1.0000000 | 0 | 0 | 8.3333333 | 18.1223455 | SCGB1A1 |
| 276 | positive regulation of synaptic transmission, GABAergic (GO:0032230) | 1/12 | 0.1136443 | 1.0000000 | 0 | 0 | 8.3333333 | 18.1223455 | GRIK1 |
| 277 | citrulline metabolic process (GO:0000052) | 1/12 | 0.1136443 | 1.0000000 | 0 | 0 | 8.3333333 | 18.1223455 | PADI3 |
| 278 | positive regulation of T cell apoptotic process (GO:0070234) | 1/12 | 0.1136443 | 1.0000000 | 0 | 0 | 8.3333333 | 18.1223455 | CCL5 |
| 279 | iron coordination entity transport (GO:1901678) | 1/12 | 0.1136443 | 1.0000000 | 0 | 0 | 8.3333333 | 18.1223455 | ABCG2 |
| 280 | regulation of development, heterochronic (GO:0040034) | 1/12 | 0.1136443 | 1.0000000 | 0 | 0 | 8.3333333 | 18.1223455 | FGF9 |
| 281 | response to water (GO:0009415) | 1/12 | 0.1136443 | 1.0000000 | 0 | 0 | 8.3333333 | 18.1223455 | SNCG |
| 282 | neutrophil mediated immunity (GO:0002446) | 1/12 | 0.1136443 | 1.0000000 | 0 | 0 | 8.3333333 | 18.1223455 | PLA2G1B |
| 283 | regulation of platelet aggregation (GO:0090330) | 1/12 | 0.1136443 | 1.0000000 | 0 | 0 | 8.3333333 | 18.1223455 | ALOX12 |
| 284 | toxin metabolic process (GO:0009404) | 1/12 | 0.1136443 | 1.0000000 | 0 | 0 | 8.3333333 | 18.1223455 | DDC |
| 285 | negative regulation by host of viral transcription (GO:0043922) | 1/12 | 0.1136443 | 1.0000000 | 0 | 0 | 8.3333333 | 18.1223455 | CCL5 |
| 286 | body morphogenesis (GO:0010171) | 1/12 | 0.1136443 | 1.0000000 | 0 | 0 | 8.3333333 | 18.1223455 | GPC3 |
| 287 | protein carboxylation (GO:0018214) | 1/12 | 0.1136443 | 1.0000000 | 0 | 0 | 8.3333333 | 18.1223455 | PROS1 |
| 288 | linoleic acid metabolic process (GO:0043651) | 1/12 | 0.1136443 | 1.0000000 | 0 | 0 | 8.3333333 | 18.1223455 | ALOX12 |
| 289 | synapsis (GO:0007129) | 1/12 | 0.1136443 | 1.0000000 | 0 | 0 | 8.3333333 | 18.1223455 | MEIOB |
| 290 | neuron-neuron synaptic transmission (GO:0007270) | 2/58 | 0.1144652 | 1.0000000 | 0 | 0 | 3.4482759 | 7.4740853 | GRID1;GRIK1 |
| 291 | cyclic nucleotide metabolic process (GO:0009187) | 2/58 | 0.1144652 | 1.0000000 | 0 | 0 | 3.4482759 | 7.4740853 | NPPC;RAMP2 |
| 292 | regulation of transmembrane receptor protein serine/threonine kinase signaling pathway (GO:0090092) | 4/186 | 0.1166797 | 1.0000000 | 0 | 0 | 2.1505376 | 4.6200488 | DMRT1;PEG10;GPC3;FBN1 |
| 293 | positive regulation of canonical Wnt signaling pathway (GO:0090263) | 2/59 | 0.1177356 | 1.0000000 | 0 | 0 | 3.3898305 | 7.2519111 | FGF9;LGR5 |
| 294 | response to fibroblast growth factor (GO:0071774) | 4/187 | 0.1183543 | 1.0000000 | 0 | 0 | 2.1390374 | 4.5648613 | FGF9;CCL5;FGF18;SCGB1A1 |
| 295 | regulation of chemotaxis (GO:0050920) | 3/120 | 0.1191064 | 1.0000000 | 0 | 0 | 2.5000000 | 5.3193443 | ROBO2;CCL5;GPR124 |
| 296 | negative regulation of leukocyte activation (GO:0002695) | 3/120 | 0.1191064 | 1.0000000 | 0 | 0 | 2.5000000 | 5.3193443 | SFTPD;SCGB1A1;BPI |
| 297 | regulation of amine transport (GO:0051952) | 2/60 | 0.1210294 | 1.0000000 | 0 | 0 | 3.3333333 | 7.0390725 | SNCG;GRIK1 |
| 298 | detection of light stimulus (GO:0009583) | 3/121 | 0.1212860 | 1.0000000 | 0 | 0 | 2.4793388 | 5.2304234 | OPN1SW;CNGA1;GPC3 |
| 299 | cellular calcium ion homeostasis (GO:0006874) | 5/261 | 0.1216875 | 1.0000000 | 0 | 0 | 1.9157088 | 4.0350552 | KISS1;CD52;GJA1;CCL5;KCNK3 |
| 300 | regulation of cell adhesion (GO:0030155) | 6/336 | 0.1216895 | 1.0000000 | 0 | 0 | 1.7857143 | 3.7612194 | SMOC2;ECM2;CCL5;ALOX12;DUSP26;JAM2 |
| 301 | cell junction organization (GO:0034330) | 4/189 | 0.1217348 | 1.0000000 | 0 | 0 | 2.1164021 | 4.4569531 | GJA1;RAMP2;DLC1;CDH7 |
| 302 | positive regulation of T cell activation (GO:0050870) | 4/189 | 0.1217348 | 1.0000000 | 0 | 0 | 2.1164021 | 4.4569531 | KLRK1;CCL5;TRAC;HLA-DQB2 |
| 303 | positive regulation of antigen processing and presentation (GO:0002579) | 1/13 | 0.1225132 | 1.0000000 | 0 | 0 | 7.6923077 | 16.1502800 | HLA-DQB2 |
| 304 | primary amino compound metabolic process (GO:1901160) | 1/13 | 0.1225132 | 1.0000000 | 0 | 0 | 7.6923077 | 16.1502800 | DDC |
| 305 | chronic inflammatory response (GO:0002544) | 1/13 | 0.1225132 | 1.0000000 | 0 | 0 | 7.6923077 | 16.1502800 | GJA1 |
| 306 | negative regulation of actin filament bundle assembly (GO:0032232) | 1/13 | 0.1225132 | 1.0000000 | 0 | 0 | 7.6923077 | 16.1502800 | DLC1 |
| 307 | mesenchymal cell proliferation (GO:0010463) | 1/13 | 0.1225132 | 1.0000000 | 0 | 0 | 7.6923077 | 16.1502800 | GPC3 |
| 308 | peptidyl-proline hydroxylation (GO:0019511) | 1/13 | 0.1225132 | 1.0000000 | 0 | 0 | 7.6923077 | 16.1502800 | P4HA3 |
| 309 | urate metabolic process (GO:0046415) | 1/13 | 0.1225132 | 1.0000000 | 0 | 0 | 7.6923077 | 16.1502800 | ABCG2 |
| 310 | oocyte development (GO:0048599) | 1/13 | 0.1225132 | 1.0000000 | 0 | 0 | 7.6923077 | 16.1502800 | DMRT1 |
| 311 | macrophage activation involved in immune response (GO:0002281) | 1/13 | 0.1225132 | 1.0000000 | 0 | 0 | 7.6923077 | 16.1502800 | CX3CR1 |
| 312 | protein-chromophore linkage (GO:0018298) | 1/13 | 0.1225132 | 1.0000000 | 0 | 0 | 7.6923077 | 16.1502800 | OPN1SW |
| 313 | lipoxygenase pathway (GO:0019372) | 1/13 | 0.1225132 | 1.0000000 | 0 | 0 | 7.6923077 | 16.1502800 | ALOX12 |
| 314 | regulation of cell maturation (GO:1903429) | 1/13 | 0.1225132 | 1.0000000 | 0 | 0 | 7.6923077 | 16.1502800 | NPPC |
| 315 | regulation of inhibitory postsynaptic membrane potential (GO:0060080) | 1/13 | 0.1225132 | 1.0000000 | 0 | 0 | 7.6923077 | 16.1502800 | GRIK1 |
| 316 | renal absorption (GO:0070293) | 1/13 | 0.1225132 | 1.0000000 | 0 | 0 | 7.6923077 | 16.1502800 | KCNJ1 |
| 317 | positive regulation of translational initiation (GO:0045948) | 1/13 | 0.1225132 | 1.0000000 | 0 | 0 | 7.6923077 | 16.1502800 | CCL5 |
| 318 | vascular endothelial growth factor signaling pathway (GO:0038084) | 1/13 | 0.1225132 | 1.0000000 | 0 | 0 | 7.6923077 | 16.1502800 | FLT4 |
| 319 | kidney development (GO:0001822) | 3/122 | 0.1234802 | 1.0000000 | 0 | 0 | 2.4590164 | 5.1434622 | ROBO2;KCNJ1;FBN1 |
| 320 | regulation of immune effector process (GO:0002697) | 5/264 | 0.1259849 | 1.0000000 | 0 | 0 | 1.8939394 | 3.9234726 | KLRK1;CD8B;PROS1;CRTAM;IFIT1 |
| 321 | signal release (GO:0023061) | 3/124 | 0.1279118 | 1.0000000 | 0 | 0 | 2.4193548 | 4.9751966 | MC4R;SLC5A7;SLC6A13 |
| 322 | cytokine-mediated signaling pathway (GO:0019221) | 6/342 | 0.1292261 | 1.0000000 | 0 | 0 | 1.7543860 | 3.5898106 | CX3CR1;CCL5;LEPR;IFIT1;HLA-DQB2;OASL |
| 323 | regulation of T cell proliferation (GO:0042129) | 3/125 | 0.1301487 | 1.0000000 | 0 | 0 | 2.4000000 | 4.8937858 | CCL5;SFTPD;SCGB1A1 |
| 324 | regulation of vasculogenesis (GO:2001212) | 1/14 | 0.1312938 | 1.0000000 | 0 | 0 | 7.1428571 | 14.5022708 | RAMP2 |
| 325 | cell communication by electrical coupling (GO:0010644) | 1/14 | 0.1312938 | 1.0000000 | 0 | 0 | 7.1428571 | 14.5022708 | GJA1 |
| 326 | superoxide anion generation (GO:0042554) | 1/14 | 0.1312938 | 1.0000000 | 0 | 0 | 7.1428571 | 14.5022708 | ALOX12 |
| 327 | regulation of endothelial cell differentiation (GO:0045601) | 1/14 | 0.1312938 | 1.0000000 | 0 | 0 | 7.1428571 | 14.5022708 | ALOX12 |
| 328 | regulation of non-canonical Wnt signaling pathway (GO:2000050) | 1/14 | 0.1312938 | 1.0000000 | 0 | 0 | 7.1428571 | 14.5022708 | GPC3 |
| 329 | regulation of feeding behavior (GO:0060259) | 1/14 | 0.1312938 | 1.0000000 | 0 | 0 | 7.1428571 | 14.5022708 | MC4R |
| 330 | positive regulation of bone resorption (GO:0045780) | 1/14 | 0.1312938 | 1.0000000 | 0 | 0 | 7.1428571 | 14.5022708 | MC4R |
| 331 | arachidonic acid secretion (GO:0050482) | 1/14 | 0.1312938 | 1.0000000 | 0 | 0 | 7.1428571 | 14.5022708 | PLA2G1B |
| 332 | positive regulation of meiosis (GO:0045836) | 1/14 | 0.1312938 | 1.0000000 | 0 | 0 | 7.1428571 | 14.5022708 | DMRT1 |
| 333 | Sertoli cell development (GO:0060009) | 1/14 | 0.1312938 | 1.0000000 | 0 | 0 | 7.1428571 | 14.5022708 | DMRT1 |
| 334 | fibril organization (GO:0097435) | 1/14 | 0.1312938 | 1.0000000 | 0 | 0 | 7.1428571 | 14.5022708 | MFAP4 |
| 335 | positive regulation of bone remodeling (GO:0046852) | 1/14 | 0.1312938 | 1.0000000 | 0 | 0 | 7.1428571 | 14.5022708 | MC4R |
| 336 | regulation of monocyte chemotaxis (GO:0090025) | 1/14 | 0.1312938 | 1.0000000 | 0 | 0 | 7.1428571 | 14.5022708 | CCL5 |
| 337 | peptidyl-arginine modification (GO:0018195) | 1/14 | 0.1312938 | 1.0000000 | 0 | 0 | 7.1428571 | 14.5022708 | PADI3 |
| 338 | icosanoid secretion (GO:0032309) | 1/14 | 0.1312938 | 1.0000000 | 0 | 0 | 7.1428571 | 14.5022708 | PLA2G1B |
| 339 | cellular response to zinc ion (GO:0071294) | 1/14 | 0.1312938 | 1.0000000 | 0 | 0 | 7.1428571 | 14.5022708 | KCNK3 |
| 340 | negative regulation of interleukin-8 production (GO:0032717) | 1/14 | 0.1312938 | 1.0000000 | 0 | 0 | 7.1428571 | 14.5022708 | BPI |
| 341 | negative regulation of T cell receptor signaling pathway (GO:0050860) | 1/14 | 0.1312938 | 1.0000000 | 0 | 0 | 7.1428571 | 14.5022708 | UBASH3A |
| 342 | regulation of dephosphorylation (GO:0035303) | 3/126 | 0.1323995 | 1.0000000 | 0 | 0 | 2.3809524 | 4.8141217 | DLC1;SLC7A14;DUSP26 |
| 343 | fatty acid oxidation (GO:0019395) | 2/64 | 0.1344226 | 1.0000000 | 0 | 0 | 3.1250000 | 6.2711468 | ACOXL;ALOX12 |
| 344 | inorganic anion transport (GO:0015698) | 3/127 | 0.1346640 | 1.0000000 | 0 | 0 | 2.3622047 | 4.7361558 | SLC4A10;GABRD;CLCA4 |
| 345 | antigen receptor-mediated signaling pathway (GO:0050851) | 3/127 | 0.1346640 | 1.0000000 | 0 | 0 | 2.3622047 | 4.7361558 | TRAC;SKAP1;HLA-DQB2 |
| 346 | regulation of vasculature development (GO:1901342) | 4/197 | 0.1356621 | 1.0000000 | 0 | 0 | 2.0304569 | 4.0560163 | CX3CR1;RAMP2;ALOX12;GPR124 |
| 347 | cellular divalent inorganic cation homeostasis (GO:0072503) | 5/271 | 0.1362797 | 1.0000000 | 0 | 0 | 1.8450185 | 3.6772068 | KISS1;CD52;GJA1;CCL5;KCNK3 |
| 348 | amino acid transport (GO:0006865) | 3/128 | 0.1369418 | 1.0000000 | 0 | 0 | 2.3437500 | 4.6598412 | SLC6A13;SLC7A14;SLC38A4 |
| 349 | lipid oxidation (GO:0034440) | 2/65 | 0.1378216 | 1.0000000 | 0 | 0 | 3.0769231 | 6.0978319 | ACOXL;ALOX12 |
| 350 | cellular response to type I interferon (GO:0071357) | 2/65 | 0.1378216 | 1.0000000 | 0 | 0 | 3.0769231 | 6.0978319 | IFIT1;OASL |
| 351 | positive regulation of cAMP biosynthetic process (GO:0030819) | 2/65 | 0.1378216 | 1.0000000 | 0 | 0 | 3.0769231 | 6.0978319 | MC4R;RAMP2 |
| 352 | interferon-gamma-mediated signaling pathway (GO:0060333) | 2/65 | 0.1378216 | 1.0000000 | 0 | 0 | 3.0769231 | 6.0978319 | HLA-DQB2;OASL |
| 353 | type I interferon signaling pathway (GO:0060337) | 2/65 | 0.1378216 | 1.0000000 | 0 | 0 | 3.0769231 | 6.0978319 | IFIT1;OASL |
| 354 | regulation of epithelial cell migration (GO:0010632) | 3/129 | 0.1392329 | 1.0000000 | 0 | 0 | 2.3255814 | 4.5851326 | FLT4;ALOX12;GPR124 |
| 355 | positive regulation of secretion (GO:0051047) | 5/273 | 0.1392883 | 1.0000000 | 0 | 0 | 1.8315018 | 3.6102742 | KISS1;PLA2G1B;CRTAM;OR51E2;GRIK1 |
| 356 | regulation of mitochondrial depolarization (GO:0051900) | 1/15 | 0.1399869 | 1.0000000 | 0 | 0 | 6.6666667 | 13.1080425 | ALOX12 |
| 357 | chondrocyte development (GO:0002063) | 1/15 | 0.1399869 | 1.0000000 | 0 | 0 | 6.6666667 | 13.1080425 | FGF18 |
| 358 | cellular response to dsRNA (GO:0071359) | 1/15 | 0.1399869 | 1.0000000 | 0 | 0 | 6.6666667 | 13.1080425 | IFIT1 |
| 359 | extracellular matrix assembly (GO:0085029) | 1/15 | 0.1399869 | 1.0000000 | 0 | 0 | 6.6666667 | 13.1080425 | MFAP4 |
| 360 | extracellular negative regulation of signal transduction (GO:1900116) | 1/15 | 0.1399869 | 1.0000000 | 0 | 0 | 6.6666667 | 13.1080425 | FBN1 |
| 361 | DNA demethylation (GO:0080111) | 1/15 | 0.1399869 | 1.0000000 | 0 | 0 | 6.6666667 | 13.1080425 | APOBEC2 |
| 362 | positive regulation of lymphocyte apoptotic process (GO:0070230) | 1/15 | 0.1399869 | 1.0000000 | 0 | 0 | 6.6666667 | 13.1080425 | CCL5 |
| 363 | renal tubule morphogenesis (GO:0061333) | 1/15 | 0.1399869 | 1.0000000 | 0 | 0 | 6.6666667 | 13.1080425 | GPC3 |
| 364 | positive regulation of smooth muscle cell migration (GO:0014911) | 1/15 | 0.1399869 | 1.0000000 | 0 | 0 | 6.6666667 | 13.1080425 | CCL5 |
| 365 | positive regulation of meiotic cell cycle (GO:0051446) | 1/15 | 0.1399869 | 1.0000000 | 0 | 0 | 6.6666667 | 13.1080425 | DMRT1 |
| 366 | extracellular regulation of signal transduction (GO:1900115) | 1/15 | 0.1399869 | 1.0000000 | 0 | 0 | 6.6666667 | 13.1080425 | FBN1 |
| 367 | positive regulation of T-helper 1 type immune response (GO:0002827) | 1/15 | 0.1399869 | 1.0000000 | 0 | 0 | 6.6666667 | 13.1080425 | HLA-DQB2 |
| 368 | renal system process involved in regulation of blood volume (GO:0001977) | 1/15 | 0.1399869 | 1.0000000 | 0 | 0 | 6.6666667 | 13.1080425 | GJA1 |
| 369 | regulation of interleukin-5 production (GO:0032674) | 1/15 | 0.1399869 | 1.0000000 | 0 | 0 | 6.6666667 | 13.1080425 | SCGB1A1 |
| 370 | dicarboxylic acid catabolic process (GO:0043649) | 1/15 | 0.1399869 | 1.0000000 | 0 | 0 | 6.6666667 | 13.1080425 | QPRT |
| 371 | negative regulation of platelet activation (GO:0010544) | 1/15 | 0.1399869 | 1.0000000 | 0 | 0 | 6.6666667 | 13.1080425 | ALOX12 |
| 372 | negative regulation of interleukin-2 production (GO:0032703) | 1/15 | 0.1399869 | 1.0000000 | 0 | 0 | 6.6666667 | 13.1080425 | SFTPD |
| 373 | response to UV-B (GO:0010224) | 1/15 | 0.1399869 | 1.0000000 | 0 | 0 | 6.6666667 | 13.1080425 | MFAP4 |
| 374 | nucleoside transport (GO:0015858) | 1/15 | 0.1399869 | 1.0000000 | 0 | 0 | 6.6666667 | 13.1080425 | GJA1 |
| 375 | calcium ion homeostasis (GO:0055074) | 5/274 | 0.1408035 | 1.0000000 | 0 | 0 | 1.8248175 | 3.5773538 | KISS1;CD52;GJA1;CCL5;KCNK3 |
| 376 | response to type I interferon (GO:0034340) | 2/66 | 0.1412394 | 1.0000000 | 0 | 0 | 3.0303030 | 5.9312088 | IFIT1;OASL |
| 377 | response to acid chemical (GO:0001101) | 5/275 | 0.1423260 | 1.0000000 | 0 | 0 | 1.8181818 | 3.5447908 | FABP3;OR51E2;SCGB1A1;SNCG;ABCG2 |
| 378 | negative regulation of hydrolase activity (GO:0051346) | 6/354 | 0.1449554 | 1.0000000 | 0 | 0 | 1.6949153 | 3.2734398 | PROS1;SLC7A14;GPC3;LEPR;A2ML1;IFIT1 |
| 379 | nervous system development (GO:0007399) | 5/277 | 0.1453926 | 1.0000000 | 0 | 0 | 1.8050542 | 3.4807180 | BEX1;DOK5;FGF18;DCX;GRIK1 |
| 380 | regulation of developmental growth (GO:0048638) | 3/133 | 0.1485253 | 1.0000000 | 0 | 0 | 2.2556391 | 4.3015042 | GJA1;FGF9;HOPX |
| 381 | protein hydroxylation (GO:0018126) | 1/16 | 0.1485935 | 1.0000000 | 0 | 0 | 6.2500000 | 11.9158813 | P4HA3 |
| 382 | positive regulation of cell adhesion mediated by integrin (GO:0033630) | 1/16 | 0.1485935 | 1.0000000 | 0 | 0 | 6.2500000 | 11.9158813 | CCL5 |
| 383 | phosphatidylinositol acyl-chain remodeling (GO:0036149) | 1/16 | 0.1485935 | 1.0000000 | 0 | 0 | 6.2500000 | 11.9158813 | PLA2G1B |
| 384 | dentate gyrus development (GO:0021542) | 1/16 | 0.1485935 | 1.0000000 | 0 | 0 | 6.2500000 | 11.9158813 | FEZF2 |
| 385 | cAMP biosynthetic process (GO:0006171) | 1/16 | 0.1485935 | 1.0000000 | 0 | 0 | 6.2500000 | 11.9158813 | RAMP2 |
| 386 | epithelial cell maturation (GO:0002070) | 1/16 | 0.1485935 | 1.0000000 | 0 | 0 | 6.2500000 | 11.9158813 | GJA1 |
| 387 | cochlea development (GO:0090102) | 1/16 | 0.1485935 | 1.0000000 | 0 | 0 | 6.2500000 | 11.9158813 | KCNK3 |
| 388 | negative regulation of cardiac muscle tissue development (GO:0055026) | 1/16 | 0.1485935 | 1.0000000 | 0 | 0 | 6.2500000 | 11.9158813 | GJA1 |
| 389 | behavioral response to pain (GO:0048266) | 1/16 | 0.1485935 | 1.0000000 | 0 | 0 | 6.2500000 | 11.9158813 | GRIK1 |
| 390 | positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway (GO:0051482) | 1/16 | 0.1485935 | 1.0000000 | 0 | 0 | 6.2500000 | 11.9158813 | KISS1 |
| 391 | negative regulation of defense response to virus (GO:0050687) | 1/16 | 0.1485935 | 1.0000000 | 0 | 0 | 6.2500000 | 11.9158813 | IFIT1 |
| 392 | establishment of skin barrier (GO:0061436) | 1/16 | 0.1485935 | 1.0000000 | 0 | 0 | 6.2500000 | 11.9158813 | ALOX12 |
| 393 | myeloid leukocyte mediated immunity (GO:0002444) | 1/16 | 0.1485935 | 1.0000000 | 0 | 0 | 6.2500000 | 11.9158813 | PLA2G1B |
| 394 | regulation of protein kinase C signaling (GO:0090036) | 1/16 | 0.1485935 | 1.0000000 | 0 | 0 | 6.2500000 | 11.9158813 | FLT4 |
| 395 | neuroblast proliferation (GO:0007405) | 1/16 | 0.1485935 | 1.0000000 | 0 | 0 | 6.2500000 | 11.9158813 | HHIP |
| 396 | cGMP biosynthetic process (GO:0006182) | 1/16 | 0.1485935 | 1.0000000 | 0 | 0 | 6.2500000 | 11.9158813 | NPPC |
| 397 | drug transmembrane transport (GO:0006855) | 1/16 | 0.1485935 | 1.0000000 | 0 | 0 | 6.2500000 | 11.9158813 | ABCG2 |
| 398 | dendritic cell chemotaxis (GO:0002407) | 1/16 | 0.1485935 | 1.0000000 | 0 | 0 | 6.2500000 | 11.9158813 | CCL5 |
| 399 | multicellular organismal aging (GO:0010259) | 1/16 | 0.1485935 | 1.0000000 | 0 | 0 | 6.2500000 | 11.9158813 | DDC |
| 400 | regulation of lymphocyte chemotaxis (GO:1901623) | 1/16 | 0.1485935 | 1.0000000 | 0 | 0 | 6.2500000 | 11.9158813 | CCL5 |
| 401 | respiratory burst (GO:0045730) | 1/16 | 0.1485935 | 1.0000000 | 0 | 0 | 6.2500000 | 11.9158813 | CD52 |
| 402 | fatty acid metabolic process (GO:0006631) | 5/280 | 0.1500455 | 1.0000000 | 0 | 0 | 1.7857143 | 3.3871721 | CH25H;FABP3;ACOXL;PLA2G1B;ALOX12 |
| 403 | positive regulation of lymphocyte mediated immunity (GO:0002708) | 2/69 | 0.1515988 | 1.0000000 | 0 | 0 | 2.8985507 | 5.4681675 | KLRK1;CRTAM |
| 404 | extracellular matrix organization (GO:0030198) | 6/359 | 0.1517582 | 1.0000000 | 0 | 0 | 1.6713092 | 3.1511980 | SMOC2;MFAP4;RAMP2;ECM2;JAM2;FBN1 |
| 405 | inorganic cation transmembrane transport (GO:0098662) | 7/440 | 0.1531269 | 1.0000000 | 0 | 0 | 1.5909091 | 2.9853222 | GPM6A;KCNJ6;KCNA3;CNGA1;KCNA4;KCNJ1;KCNK3 |
| 406 | extracellular structure organization (GO:0043062) | 6/360 | 0.1531358 | 1.0000000 | 0 | 0 | 1.6666667 | 3.1273836 | SMOC2;MFAP4;RAMP2;ECM2;JAM2;FBN1 |
| 407 | cellular metal ion homeostasis (GO:0006875) | 6/361 | 0.1545190 | 1.0000000 | 0 | 0 | 1.6620499 | 3.1037753 | KISS1;CD52;GJA1;CCL5;KCNK3;ABCG2 |
| 408 | leukocyte mediated immunity (GO:0002443) | 2/70 | 0.1550849 | 1.0000000 | 0 | 0 | 2.8571429 | 5.3250926 | PLA2G1B;CRTAM |
| 409 | phosphatidylglycerol acyl-chain remodeling (GO:0036148) | 1/17 | 0.1571144 | 1.0000000 | 0 | 0 | 5.8823529 | 10.8869493 | PLA2G1B |
| 410 | forebrain neuron development (GO:0021884) | 1/17 | 0.1571144 | 1.0000000 | 0 | 0 | 5.8823529 | 10.8869493 | ROBO2 |
| 411 | male meiosis I (GO:0007141) | 1/17 | 0.1571144 | 1.0000000 | 0 | 0 | 5.8823529 | 10.8869493 | MEIOB |
| 412 | trophectodermal cell differentiation (GO:0001829) | 1/17 | 0.1571144 | 1.0000000 | 0 | 0 | 5.8823529 | 10.8869493 | HOPX |
| 413 | phosphatidylserine acyl-chain remodeling (GO:0036150) | 1/17 | 0.1571144 | 1.0000000 | 0 | 0 | 5.8823529 | 10.8869493 | PLA2G1B |
| 414 | synaptic transmission, cholinergic (GO:0007271) | 1/17 | 0.1571144 | 1.0000000 | 0 | 0 | 5.8823529 | 10.8869493 | SLC5A7 |
| 415 | fatty acid derivative transport (GO:1901571) | 1/17 | 0.1571144 | 1.0000000 | 0 | 0 | 5.8823529 | 10.8869493 | PLA2G1B |
| 416 | NAD biosynthetic process (GO:0009435) | 1/17 | 0.1571144 | 1.0000000 | 0 | 0 | 5.8823529 | 10.8869493 | QPRT |
| 417 | monocyte chemotaxis (GO:0002548) | 1/17 | 0.1571144 | 1.0000000 | 0 | 0 | 5.8823529 | 10.8869493 | CCL5 |
| 418 | icosanoid transport (GO:0071715) | 1/17 | 0.1571144 | 1.0000000 | 0 | 0 | 5.8823529 | 10.8869493 | PLA2G1B |
| 419 | sex differentiation (GO:0007548) | 1/17 | 0.1571144 | 1.0000000 | 0 | 0 | 5.8823529 | 10.8869493 | DMRT1 |
| 420 | neurotransmitter biosynthetic process (GO:0042136) | 1/17 | 0.1571144 | 1.0000000 | 0 | 0 | 5.8823529 | 10.8869493 | SLC5A7 |
| 421 | regulation of G-protein coupled receptor protein signaling pathway (GO:0008277) | 3/137 | 0.1580124 | 1.0000000 | 0 | 0 | 2.1897810 | 4.0403245 | RAMP2;CCL5;CNGA1 |
| 422 | positive regulation of developmental growth (GO:0048639) | 2/71 | 0.1585864 | 1.0000000 | 0 | 0 | 2.8169014 | 5.1871985 | FGF9;HOPX |
| 423 | renal system process (GO:0003014) | 2/71 | 0.1585864 | 1.0000000 | 0 | 0 | 2.8169014 | 5.1871985 | GJA1;KCNJ1 |
| 424 | response to peptide hormone (GO:0043434) | 6/364 | 0.1587019 | 1.0000000 | 0 | 0 | 1.6483516 | 3.0341663 | MC4R;GJA1;FABP3;FGF9;PLA2G1B;FGF18 |
| 425 | DNA modification (GO:0006304) | 2/72 | 0.1621027 | 1.0000000 | 0 | 0 | 2.7777778 | 5.0542366 | APOBEC2;APOBEC3H |
| 426 | positive regulation of cAMP metabolic process (GO:0030816) | 2/72 | 0.1621027 | 1.0000000 | 0 | 0 | 2.7777778 | 5.0542366 | MC4R;RAMP2 |
| 427 | positive regulation of peptidase activity (GO:0010952) | 3/139 | 0.1628250 | 1.0000000 | 0 | 0 | 2.1582734 | 3.9174379 | PCOLCE2;DLC1;ALOX12 |
| 428 | negative regulation of antigen receptor-mediated signaling pathway (GO:0050858) | 1/18 | 0.1655504 | 1.0000000 | 0 | 0 | 5.5555556 | 9.9915545 | UBASH3A |
| 429 | axonal fasciculation (GO:0007413) | 1/18 | 0.1655504 | 1.0000000 | 0 | 0 | 5.5555556 | 9.9915545 | FEZF2 |
| 430 | indolalkylamine metabolic process (GO:0006586) | 1/18 | 0.1655504 | 1.0000000 | 0 | 0 | 5.5555556 | 9.9915545 | DDC |
| 431 | embryonic digestive tract development (GO:0048566) | 1/18 | 0.1655504 | 1.0000000 | 0 | 0 | 5.5555556 | 9.9915545 | FGF9 |
| 432 | positive regulation of cGMP biosynthetic process (GO:0030828) | 1/18 | 0.1655504 | 1.0000000 | 0 | 0 | 5.5555556 | 9.9915545 | NPPC |
| 433 | catechol-containing compound biosynthetic process (GO:0009713) | 1/18 | 0.1655504 | 1.0000000 | 0 | 0 | 5.5555556 | 9.9915545 | DDC |
| 434 | negative regulation of T cell apoptotic process (GO:0070233) | 1/18 | 0.1655504 | 1.0000000 | 0 | 0 | 5.5555556 | 9.9915545 | CCL5 |
| 435 | catecholamine biosynthetic process (GO:0042423) | 1/18 | 0.1655504 | 1.0000000 | 0 | 0 | 5.5555556 | 9.9915545 | DDC |
| 436 | regulation of dopamine secretion (GO:0014059) | 1/18 | 0.1655504 | 1.0000000 | 0 | 0 | 5.5555556 | 9.9915545 | SNCG |
| 437 | fibrinolysis (GO:0042730) | 1/18 | 0.1655504 | 1.0000000 | 0 | 0 | 5.5555556 | 9.9915545 | PROS1 |
| 438 | positive regulation of chondrocyte differentiation (GO:0032332) | 1/18 | 0.1655504 | 1.0000000 | 0 | 0 | 5.5555556 | 9.9915545 | FGF18 |
| 439 | DNA dealkylation (GO:0035510) | 1/18 | 0.1655504 | 1.0000000 | 0 | 0 | 5.5555556 | 9.9915545 | APOBEC2 |
| 440 | negative regulation of transforming growth factor beta receptor signaling pathway (GO:0030512) | 2/73 | 0.1656331 | 1.0000000 | 0 | 0 | 2.7397260 | 4.9259739 | PEG10;FBN1 |
| 441 | regulation of BMP signaling pathway (GO:0030510) | 2/73 | 0.1656331 | 1.0000000 | 0 | 0 | 2.7397260 | 4.9259739 | GPC3;FBN1 |
| 442 | negative regulation of T cell activation (GO:0050868) | 2/73 | 0.1656331 | 1.0000000 | 0 | 0 | 2.7397260 | 4.9259739 | SFTPD;SCGB1A1 |
| 443 | divalent inorganic cation homeostasis (GO:0072507) | 5/291 | 0.1676310 | 1.0000000 | 0 | 0 | 1.7182131 | 3.0687119 | KISS1;CD52;GJA1;CCL5;KCNK3 |
| 444 | regulation of system process (GO:0044057) | 6/371 | 0.1686521 | 1.0000000 | 0 | 0 | 1.6172507 | 2.8785729 | KISS1;NPPC;GJA1;OR51E2;ALOX12;HOPX |
| 445 | negative regulation of response to external stimulus (GO:0032102) | 4/215 | 0.1691759 | 1.0000000 | 0 | 0 | 1.8604651 | 3.3057044 | ROBO2;PROS1;ALOX12;IFIT1 |
| 446 | regulation of organ growth (GO:0046620) | 2/74 | 0.1691769 | 1.0000000 | 0 | 0 | 2.7027027 | 4.8021906 | GJA1;FGF9 |
| 447 | blood vessel morphogenesis (GO:0048514) | 2/74 | 0.1691769 | 1.0000000 | 0 | 0 | 2.7027027 | 4.8021906 | GJA1;FLT4 |
| 448 | regulation of peptidase activity (GO:0052547) | 6/372 | 0.1700947 | 1.0000000 | 0 | 0 | 1.6129032 | 2.8570965 | PCOLCE2;DLC1;PROS1;GPC3;ALOX12;A2ML1 |
| 449 | response to toxic substance (GO:0009636) | 3/142 | 0.1701252 | 1.0000000 | 0 | 0 | 2.1126761 | 3.7420149 | DDC;CCL5;CYP2F1 |
| 450 | neutrophil activation (GO:0042119) | 1/19 | 0.1739024 | 1.0000000 | 0 | 0 | 5.2631579 | 9.2066381 | CCL5 |
| 451 | nucleotide transport (GO:0006862) | 1/19 | 0.1739024 | 1.0000000 | 0 | 0 | 5.2631579 | 9.2066381 | GJA1 |
| 452 | reflex (GO:0060004) | 1/19 | 0.1739024 | 1.0000000 | 0 | 0 | 5.2631579 | 9.2066381 | GJA1 |
| 453 | regulation of water loss via skin (GO:0033561) | 1/19 | 0.1739024 | 1.0000000 | 0 | 0 | 5.2631579 | 9.2066381 | ALOX12 |
| 454 | regulation of cGMP biosynthetic process (GO:0030826) | 1/19 | 0.1739024 | 1.0000000 | 0 | 0 | 5.2631579 | 9.2066381 | NPPC |
| 455 | regulation of execution phase of apoptosis (GO:1900117) | 1/19 | 0.1739024 | 1.0000000 | 0 | 0 | 5.2631579 | 9.2066381 | DLC1 |
| 456 | innate immune response in mucosa (GO:0002227) | 1/19 | 0.1739024 | 1.0000000 | 0 | 0 | 5.2631579 | 9.2066381 | PLA2G1B |
| 457 | regulation of interleukin-2 biosynthetic process (GO:0045076) | 1/19 | 0.1739024 | 1.0000000 | 0 | 0 | 5.2631579 | 9.2066381 | SFTPD |
| 458 | retinal ganglion cell axon guidance (GO:0031290) | 1/19 | 0.1739024 | 1.0000000 | 0 | 0 | 5.2631579 | 9.2066381 | ROBO2 |
| 459 | cell-cell junction assembly (GO:0007043) | 2/77 | 0.1798830 | 1.0000000 | 0 | 0 | 2.5974026 | 4.4557106 | GJA1;RAMP2 |
| 460 | regulation of defense response to virus (GO:0050688) | 2/77 | 0.1798830 | 1.0000000 | 0 | 0 | 2.5974026 | 4.4557106 | CD8B;IFIT1 |
| 461 | multi-organism behavior (GO:0051705) | 2/77 | 0.1798830 | 1.0000000 | 0 | 0 | 2.5974026 | 4.4557106 | GRID1;SNCG |
| 462 | modulation by host of viral transcription (GO:0043921) | 1/20 | 0.1821712 | 1.0000000 | 0 | 0 | 5.0000000 | 8.5140422 | CCL5 |
| 463 | modulation by host of symbiont transcription (GO:0052472) | 1/20 | 0.1821712 | 1.0000000 | 0 | 0 | 5.0000000 | 8.5140422 | CCL5 |
| 464 | T cell mediated immunity (GO:0002456) | 1/20 | 0.1821712 | 1.0000000 | 0 | 0 | 5.0000000 | 8.5140422 | CRTAM |
| 465 | cellular biogenic amine biosynthetic process (GO:0042401) | 1/20 | 0.1821712 | 1.0000000 | 0 | 0 | 5.0000000 | 8.5140422 | DDC |
| 466 | positive regulation of cGMP metabolic process (GO:0030825) | 1/20 | 0.1821712 | 1.0000000 | 0 | 0 | 5.0000000 | 8.5140422 | NPPC |
| 467 | regulation of membrane repolarization (GO:0060306) | 1/20 | 0.1821712 | 1.0000000 | 0 | 0 | 5.0000000 | 8.5140422 | GJA1 |
| 468 | negative regulation of endothelial cell apoptotic process (GO:2000352) | 1/20 | 0.1821712 | 1.0000000 | 0 | 0 | 5.0000000 | 8.5140422 | RAMP2 |
| 469 | renal system process involved in regulation of systemic arterial blood pressure (GO:0003071) | 1/20 | 0.1821712 | 1.0000000 | 0 | 0 | 5.0000000 | 8.5140422 | GJA1 |
| 470 | positive regulation of cardiac muscle cell proliferation (GO:0060045) | 1/20 | 0.1821712 | 1.0000000 | 0 | 0 | 5.0000000 | 8.5140422 | FGF9 |
| 471 | nicotinamide nucleotide biosynthetic process (GO:0019359) | 1/20 | 0.1821712 | 1.0000000 | 0 | 0 | 5.0000000 | 8.5140422 | QPRT |
| 472 | neuromuscular synaptic transmission (GO:0007274) | 1/20 | 0.1821712 | 1.0000000 | 0 | 0 | 5.0000000 | 8.5140422 | SLC5A7 |
| 473 | epithelial tube branching involved in lung morphogenesis (GO:0060441) | 1/20 | 0.1821712 | 1.0000000 | 0 | 0 | 5.0000000 | 8.5140422 | HHIP |
| 474 | sialylation (GO:0097503) | 1/20 | 0.1821712 | 1.0000000 | 0 | 0 | 5.0000000 | 8.5140422 | ST6GAL2 |
| 475 | pyridine nucleotide biosynthetic process (GO:0019363) | 1/20 | 0.1821712 | 1.0000000 | 0 | 0 | 5.0000000 | 8.5140422 | QPRT |
| 476 | positive regulation of T cell migration (GO:2000406) | 1/20 | 0.1821712 | 1.0000000 | 0 | 0 | 5.0000000 | 8.5140422 | CCL5 |
| 477 | regulation of amino acid transport (GO:0051955) | 1/20 | 0.1821712 | 1.0000000 | 0 | 0 | 5.0000000 | 8.5140422 | GRIK1 |
| 478 | positive regulation of leukocyte mediated immunity (GO:0002705) | 2/78 | 0.1834746 | 1.0000000 | 0 | 0 | 2.5641026 | 4.3478946 | KLRK1;CRTAM |
| 479 | ovulation cycle process (GO:0022602) | 2/78 | 0.1834746 | 1.0000000 | 0 | 0 | 2.5641026 | 4.3478946 | ROBO2;KISS1 |
| 480 | cation homeostasis (GO:0055080) | 7/465 | 0.1855520 | 1.0000000 | 0 | 0 | 1.5053763 | 2.5356861 | KISS1;CD52;GJA1;CCL5;SLC4A10;KCNK3;ABCG2 |
| 481 | regulation of blood coagulation (GO:0030193) | 2/79 | 0.1870767 | 1.0000000 | 0 | 0 | 2.5316456 | 4.2436366 | PROS1;ALOX12 |
| 482 | regulation of hemostasis (GO:1900046) | 2/79 | 0.1870767 | 1.0000000 | 0 | 0 | 2.5316456 | 4.2436366 | PROS1;ALOX12 |
| 483 | response to peptide (GO:1901652) | 6/384 | 0.1878023 | 1.0000000 | 0 | 0 | 1.5625000 | 2.6130713 | MC4R;GJA1;FABP3;FGF9;PLA2G1B;FGF18 |
| 484 | modulation of transcription in other organism involved in symbiotic interaction (GO:0052312) | 1/21 | 0.1903576 | 1.0000000 | 0 | 0 | 4.7619048 | 7.8992886 | CCL5 |
| 485 | amine biosynthetic process (GO:0009309) | 1/21 | 0.1903576 | 1.0000000 | 0 | 0 | 4.7619048 | 7.8992886 | DDC |
| 486 | bile acid biosynthetic process (GO:0006699) | 1/21 | 0.1903576 | 1.0000000 | 0 | 0 | 4.7619048 | 7.8992886 | CH25H |
| 487 | dendritic cell migration (GO:0036336) | 1/21 | 0.1903576 | 1.0000000 | 0 | 0 | 4.7619048 | 7.8992886 | CCL5 |
| 488 | granulocyte activation (GO:0036230) | 1/21 | 0.1903576 | 1.0000000 | 0 | 0 | 4.7619048 | 7.8992886 | CCL5 |
| 489 | regulation of T-helper 1 type immune response (GO:0002825) | 1/21 | 0.1903576 | 1.0000000 | 0 | 0 | 4.7619048 | 7.8992886 | HLA-DQB2 |
| 490 | regulation of interleukin-4 production (GO:0032673) | 1/21 | 0.1903576 | 1.0000000 | 0 | 0 | 4.7619048 | 7.8992886 | SCGB1A1 |
| 491 | positive regulation of phospholipase activity (GO:0010518) | 2/80 | 0.1906887 | 1.0000000 | 0 | 0 | 2.5000000 | 4.1427819 | PLA2G1B;CCL5 |
| 492 | negative regulation of DNA metabolic process (GO:0051053) | 2/80 | 0.1906887 | 1.0000000 | 0 | 0 | 2.5000000 | 4.1427819 | NPPC;APOBEC3H |
| 493 | retinoid metabolic process (GO:0001523) | 2/81 | 0.1943101 | 1.0000000 | 0 | 0 | 2.4691358 | 4.0451846 | OPN1SW;GPC3 |
| 494 | pyrimidine-containing compound metabolic process (GO:0072527) | 2/81 | 0.1943101 | 1.0000000 | 0 | 0 | 2.4691358 | 4.0451846 | APOBEC2;APOBEC3H |
| 495 | positive regulation of viral process (GO:0048524) | 2/81 | 0.1943101 | 1.0000000 | 0 | 0 | 2.4691358 | 4.0451846 | CCL5;IFIT1 |
| 496 | regulation of canonical Wnt signaling pathway (GO:0060828) | 3/152 | 0.1950998 | 1.0000000 | 0 | 0 | 1.9736842 | 3.2254818 | FGF9;GPC3;LGR5 |
| 497 | positive regulation of cytosolic calcium ion concentration (GO:0007204) | 3/152 | 0.1950998 | 1.0000000 | 0 | 0 | 1.9736842 | 3.2254818 | KISS1;CD52;GJA1 |
| 498 | receptor-mediated endocytosis (GO:0006898) | 3/152 | 0.1950998 | 1.0000000 | 0 | 0 | 1.9736842 | 3.2254818 | RAMP2;SFTPD;LRP1B |
| 499 | cellular cation homeostasis (GO:0030003) | 6/389 | 0.1953866 | 1.0000000 | 0 | 0 | 1.5424165 | 2.5184188 | KISS1;CD52;GJA1;CCL5;KCNK3;ABCG2 |
| 500 | male meiosis (GO:0007140) | 1/22 | 0.1984626 | 1.0000000 | 0 | 0 | 4.5454545 | 7.3507034 | MEIOB |
| 501 | regulation of cGMP metabolic process (GO:0030823) | 1/22 | 0.1984626 | 1.0000000 | 0 | 0 | 4.5454545 | 7.3507034 | NPPC |
| 502 | positive regulation of cardiac muscle tissue growth (GO:0055023) | 1/22 | 0.1984626 | 1.0000000 | 0 | 0 | 4.5454545 | 7.3507034 | FGF9 |
| 503 | central nervous system projection neuron axonogenesis (GO:0021952) | 1/22 | 0.1984626 | 1.0000000 | 0 | 0 | 4.5454545 | 7.3507034 | DCX |
| 504 | meiosis I (GO:0007127) | 1/22 | 0.1984626 | 1.0000000 | 0 | 0 | 4.5454545 | 7.3507034 | MEIOB |
| 505 | myofibril assembly (GO:0030239) | 1/22 | 0.1984626 | 1.0000000 | 0 | 0 | 4.5454545 | 7.3507034 | MYOZ1 |
| 506 | apoptotic process involved in development (GO:1902742) | 1/22 | 0.1984626 | 1.0000000 | 0 | 0 | 4.5454545 | 7.3507034 | ROBO2 |
| 507 | organic hydroxy compound metabolic process (GO:1901615) | 7/476 | 0.2006601 | 1.0000000 | 0 | 0 | 1.4705882 | 2.3619745 | CH25H;DDC;ADH1C;ADH1B;PLA2G1B;LEPR;ALOX12 |
| 508 | cellular response to abiotic stimulus (GO:0071214) | 4/232 | 0.2031974 | 1.0000000 | 0 | 0 | 1.7241379 | 2.7475468 | MFAP4;GJA1;CNGA1;SNCG |
| 509 | positive regulation of MAPK cascade (GO:0043410) | 6/395 | 0.2046385 | 1.0000000 | 0 | 0 | 1.5189873 | 2.4098887 | KISS1;FGF9;PLA2G1B;FLT4;DIRAS2;FGF18 |
| 510 | reactive oxygen species metabolic process (GO:0072593) | 2/84 | 0.2052251 | 1.0000000 | 0 | 0 | 2.3809524 | 3.7705904 | SFTPD;ALOX12 |
| 511 | chloride transmembrane transport (GO:1902476) | 2/84 | 0.2052251 | 1.0000000 | 0 | 0 | 2.3809524 | 3.7705904 | GABRD;CLCA4 |
| 512 | DNA catabolic process, exonucleolytic (GO:0000738) | 1/23 | 0.2064868 | 1.0000000 | 0 | 0 | 4.3478261 | 6.8587782 | MEIOB |
| 513 | endothelial cell differentiation (GO:0045446) | 1/23 | 0.2064868 | 1.0000000 | 0 | 0 | 4.3478261 | 6.8587782 | SCUBE1 |
| 514 | cell-substrate adherens junction assembly (GO:0007045) | 1/23 | 0.2064868 | 1.0000000 | 0 | 0 | 4.3478261 | 6.8587782 | DLC1 |
| 515 | focal adhesion assembly (GO:0048041) | 1/23 | 0.2064868 | 1.0000000 | 0 | 0 | 4.3478261 | 6.8587782 | DLC1 |
| 516 | regulation of macrophage activation (GO:0043030) | 1/23 | 0.2064868 | 1.0000000 | 0 | 0 | 4.3478261 | 6.8587782 | BPI |
| 517 | detection of biotic stimulus (GO:0009595) | 1/23 | 0.2064868 | 1.0000000 | 0 | 0 | 4.3478261 | 6.8587782 | CRTAM |
| 518 | phosphatidylethanolamine acyl-chain remodeling (GO:0036152) | 1/23 | 0.2064868 | 1.0000000 | 0 | 0 | 4.3478261 | 6.8587782 | PLA2G1B |
| 519 | regulation of activin receptor signaling pathway (GO:0032925) | 1/23 | 0.2064868 | 1.0000000 | 0 | 0 | 4.3478261 | 6.8587782 | DMRT1 |
| 520 | positive regulation vascular endothelial growth factor production (GO:0010575) | 1/23 | 0.2064868 | 1.0000000 | 0 | 0 | 4.3478261 | 6.8587782 | FLT4 |
| 521 | drug transport (GO:0015893) | 1/23 | 0.2064868 | 1.0000000 | 0 | 0 | 4.3478261 | 6.8587782 | ABCG2 |
| 522 | positive regulation of organic acid transport (GO:0032892) | 1/23 | 0.2064868 | 1.0000000 | 0 | 0 | 4.3478261 | 6.8587782 | GRIK1 |
| 523 | negative regulation of organ growth (GO:0046621) | 1/23 | 0.2064868 | 1.0000000 | 0 | 0 | 4.3478261 | 6.8587782 | GJA1 |
| 524 | regulation of T cell migration (GO:2000404) | 1/23 | 0.2064868 | 1.0000000 | 0 | 0 | 4.3478261 | 6.8587782 | CCL5 |
| 525 | positive regulation of amine transport (GO:0051954) | 1/23 | 0.2064868 | 1.0000000 | 0 | 0 | 4.3478261 | 6.8587782 | GRIK1 |
| 526 | regulation of coagulation (GO:0050818) | 2/85 | 0.2088786 | 1.0000000 | 0 | 0 | 2.3529412 | 3.6847110 | PROS1;ALOX12 |
| 527 | female pregnancy (GO:0007565) | 2/85 | 0.2088786 | 1.0000000 | 0 | 0 | 2.3529412 | 3.6847110 | RAMP2;SCGB1A1 |
| 528 | positive regulation of synaptic transmission (GO:0050806) | 2/85 | 0.2088786 | 1.0000000 | 0 | 0 | 2.3529412 | 3.6847110 | KISS1;GRIK1 |
| 529 | cellular response to light stimulus (GO:0071482) | 2/85 | 0.2088786 | 1.0000000 | 0 | 0 | 2.3529412 | 3.6847110 | MFAP4;CNGA1 |
| 530 | single organismal cell-cell adhesion (GO:0016337) | 4/235 | 0.2094034 | 1.0000000 | 0 | 0 | 1.7021277 | 2.6612640 | CCL5;ANXA9;JAM2;CDH7 |
| 531 | regulation of reproductive process (GO:2000241) | 2/86 | 0.2125388 | 1.0000000 | 0 | 0 | 2.3255814 | 3.6014667 | NPPC;DMRT1 |
| 532 | myeloid leukocyte activation (GO:0002274) | 2/86 | 0.2125388 | 1.0000000 | 0 | 0 | 2.3255814 | 3.6014667 | CX3CR1;CCL5 |
| 533 | vascular process in circulatory system (GO:0003018) | 2/86 | 0.2125388 | 1.0000000 | 0 | 0 | 2.3255814 | 3.6014667 | NPPC;RAMP2 |
| 534 | positive regulation of filopodium assembly (GO:0051491) | 1/24 | 0.2144310 | 1.0000000 | 0 | 0 | 4.1666667 | 6.4156966 | GPM6A |
| 535 | mucosal immune response (GO:0002385) | 1/24 | 0.2144310 | 1.0000000 | 0 | 0 | 4.1666667 | 6.4156966 | PLA2G1B |
| 536 | vascular endothelial growth factor receptor signaling pathway (GO:0048010) | 1/24 | 0.2144310 | 1.0000000 | 0 | 0 | 4.1666667 | 6.4156966 | FLT4 |
| 537 | positive regulation of leukocyte apoptotic process (GO:2000108) | 1/24 | 0.2144310 | 1.0000000 | 0 | 0 | 4.1666667 | 6.4156966 | CCL5 |
| 538 | gamma-aminobutyric acid signaling pathway (GO:0007214) | 1/24 | 0.2144310 | 1.0000000 | 0 | 0 | 4.1666667 | 6.4156966 | GABBR2 |
| 539 | negative regulation of adenylate cyclase activity (GO:0007194) | 1/24 | 0.2144310 | 1.0000000 | 0 | 0 | 4.1666667 | 6.4156966 | GABBR2 |
| 540 | regulation of fatty acid oxidation (GO:0046320) | 1/24 | 0.2144310 | 1.0000000 | 0 | 0 | 4.1666667 | 6.4156966 | FABP3 |
| 541 | negative regulation of muscle cell apoptotic process (GO:0010656) | 1/24 | 0.2144310 | 1.0000000 | 0 | 0 | 4.1666667 | 6.4156966 | ALOX12 |
| 542 | leukotriene biosynthetic process (GO:0019370) | 1/24 | 0.2144310 | 1.0000000 | 0 | 0 | 4.1666667 | 6.4156966 | PLA2G1B |
| 543 | cofactor transport (GO:0051181) | 1/24 | 0.2144310 | 1.0000000 | 0 | 0 | 4.1666667 | 6.4156966 | ABCG2 |
| 544 | cGMP metabolic process (GO:0046068) | 1/24 | 0.2144310 | 1.0000000 | 0 | 0 | 4.1666667 | 6.4156966 | NPPC |
| 545 | pyridine-containing compound biosynthetic process (GO:0072525) | 1/24 | 0.2144310 | 1.0000000 | 0 | 0 | 4.1666667 | 6.4156966 | QPRT |
| 546 | negative regulation of viral transcription (GO:0032897) | 1/24 | 0.2144310 | 1.0000000 | 0 | 0 | 4.1666667 | 6.4156966 | CCL5 |
| 547 | positive regulation of response to biotic stimulus (GO:0002833) | 1/24 | 0.2144310 | 1.0000000 | 0 | 0 | 4.1666667 | 6.4156966 | CRTAM |
| 548 | positive regulation of lymphocyte migration (GO:2000403) | 1/24 | 0.2144310 | 1.0000000 | 0 | 0 | 4.1666667 | 6.4156966 | CCL5 |
| 549 | cellular ion homeostasis (GO:0006873) | 6/402 | 0.2156295 | 1.0000000 | 0 | 0 | 1.4925373 | 2.2898409 | KISS1;CD52;GJA1;CCL5;KCNK3;ABCG2 |
| 550 | regulation of ion homeostasis (GO:2000021) | 3/160 | 0.2156879 | 1.0000000 | 0 | 0 | 1.8750000 | 2.8761054 | GJA1;PLA2G1B;ALOX12 |
| 551 | diterpenoid metabolic process (GO:0016101) | 2/87 | 0.2162053 | 1.0000000 | 0 | 0 | 2.2988506 | 3.5207517 | OPN1SW;GPC3 |
| 552 | regulation of protein secretion (GO:0050708) | 3/161 | 0.2182939 | 1.0000000 | 0 | 0 | 1.8633540 | 2.8358630 | PLA2G1B;CRTAM;OR51E2 |
| 553 | regulation of ERK1 and ERK2 cascade (GO:0070372) | 3/161 | 0.2182939 | 1.0000000 | 0 | 0 | 1.8633540 | 2.8358630 | FLT4;FGF18;DUSP26 |
| 554 | fatty acid derivative metabolic process (GO:1901568) | 2/88 | 0.2198775 | 1.0000000 | 0 | 0 | 2.2727273 | 3.4424652 | PLA2G1B;ALOX12 |
| 555 | icosanoid metabolic process (GO:0006690) | 2/88 | 0.2198775 | 1.0000000 | 0 | 0 | 2.2727273 | 3.4424652 | PLA2G1B;ALOX12 |
| 556 | membrane hyperpolarization (GO:0060081) | 1/25 | 0.2222961 | 1.0000000 | 0 | 0 | 4.0000000 | 6.0149794 | GRIK1 |
| 557 | peptidyl-glutamic acid modification (GO:0018200) | 1/25 | 0.2222961 | 1.0000000 | 0 | 0 | 4.0000000 | 6.0149794 | PROS1 |
| 558 | regulation of T cell receptor signaling pathway (GO:0050856) | 1/25 | 0.2222961 | 1.0000000 | 0 | 0 | 4.0000000 | 6.0149794 | UBASH3A |
| 559 | regulation of potassium ion transmembrane transporter activity (GO:1901016) | 1/25 | 0.2222961 | 1.0000000 | 0 | 0 | 4.0000000 | 6.0149794 | KCNJ1 |
| 560 | negative regulation of cyclase activity (GO:0031280) | 1/25 | 0.2222961 | 1.0000000 | 0 | 0 | 4.0000000 | 6.0149794 | GABBR2 |
| 561 | osteoclast differentiation (GO:0030316) | 1/25 | 0.2222961 | 1.0000000 | 0 | 0 | 4.0000000 | 6.0149794 | GPC3 |
| 562 | positive regulation of heart growth (GO:0060421) | 1/25 | 0.2222961 | 1.0000000 | 0 | 0 | 4.0000000 | 6.0149794 | FGF9 |
| 563 | response to iron ion (GO:0010039) | 1/25 | 0.2222961 | 1.0000000 | 0 | 0 | 4.0000000 | 6.0149794 | ABCG2 |
| 564 | positive regulation of cartilage development (GO:0061036) | 1/25 | 0.2222961 | 1.0000000 | 0 | 0 | 4.0000000 | 6.0149794 | FGF18 |
| 565 | regulation of autophagy (GO:0010506) | 2/89 | 0.2235550 | 1.0000000 | 0 | 0 | 2.2471910 | 3.3665119 | SOGA3;KIAA0408 |
| 566 | regulation of phospholipase activity (GO:0010517) | 2/89 | 0.2235550 | 1.0000000 | 0 | 0 | 2.2471910 | 3.3665119 | PLA2G1B;CCL5 |
| 567 | protein tetramerization (GO:0051262) | 2/89 | 0.2235550 | 1.0000000 | 0 | 0 | 2.2471910 | 3.3665119 | CCL5;TGM3 |
| 568 | positive regulation of lymphocyte activation (GO:0051251) | 4/243 | 0.2262091 | 1.0000000 | 0 | 0 | 1.6460905 | 2.4465772 | KLRK1;CCL5;TRAC;HLA-DQB2 |
| 569 | epithelial tube morphogenesis (GO:0060562) | 2/90 | 0.2272373 | 1.0000000 | 0 | 0 | 2.2222222 | 3.2928009 | GJA1;GPC3 |
| 570 | positive regulation of lipase activity (GO:0060193) | 2/90 | 0.2272373 | 1.0000000 | 0 | 0 | 2.2222222 | 3.2928009 | PLA2G1B;CCL5 |
| 571 | regulation of neurotransmitter levels (GO:0001505) | 2/90 | 0.2272373 | 1.0000000 | 0 | 0 | 2.2222222 | 3.2928009 | SLC5A7;SLC6A13 |
| 572 | positive regulation of endocytosis (GO:0045807) | 2/90 | 0.2272373 | 1.0000000 | 0 | 0 | 2.2222222 | 3.2928009 | SFTPD;GPC3 |
| 573 | macrophage activation (GO:0042116) | 1/26 | 0.2300829 | 1.0000000 | 0 | 0 | 3.8461538 | 5.6512139 | CX3CR1 |
| 574 | indole-containing compound metabolic process (GO:0042430) | 1/26 | 0.2300829 | 1.0000000 | 0 | 0 | 3.8461538 | 5.6512139 | DDC |
| 575 | positive regulation of vasoconstriction (GO:0045907) | 1/26 | 0.2300829 | 1.0000000 | 0 | 0 | 3.8461538 | 5.6512139 | GJA1 |
| 576 | leukocyte mediated cytotoxicity (GO:0001909) | 1/26 | 0.2300829 | 1.0000000 | 0 | 0 | 3.8461538 | 5.6512139 | CRTAM |
| 577 | regulation of defense response to virus by host (GO:0050691) | 1/26 | 0.2300829 | 1.0000000 | 0 | 0 | 3.8461538 | 5.6512139 | IFIT1 |
| 578 | phosphatidylcholine acyl-chain remodeling (GO:0036151) | 1/26 | 0.2300829 | 1.0000000 | 0 | 0 | 3.8461538 | 5.6512139 | PLA2G1B |
| 579 | positive regulation of tissue remodeling (GO:0034105) | 1/26 | 0.2300829 | 1.0000000 | 0 | 0 | 3.8461538 | 5.6512139 | MC4R |
| 580 | negative regulation of lyase activity (GO:0051350) | 1/26 | 0.2300829 | 1.0000000 | 0 | 0 | 3.8461538 | 5.6512139 | GABBR2 |
| 581 | negative regulation of response to biotic stimulus (GO:0002832) | 1/26 | 0.2300829 | 1.0000000 | 0 | 0 | 3.8461538 | 5.6512139 | IFIT1 |
| 582 | organ or tissue specific immune response (GO:0002251) | 1/26 | 0.2300829 | 1.0000000 | 0 | 0 | 3.8461538 | 5.6512139 | PLA2G1B |
| 583 | antibacterial humoral response (GO:0019731) | 1/26 | 0.2300829 | 1.0000000 | 0 | 0 | 3.8461538 | 5.6512139 | PLA2G1B |
| 584 | positive regulation of calcium ion transport (GO:0051928) | 2/91 | 0.2309240 | 1.0000000 | 0 | 0 | 2.1978022 | 3.2212458 | PLA2G1B;CCL5 |
| 585 | organic hydroxy compound biosynthetic process (GO:1901617) | 3/166 | 0.2314186 | 1.0000000 | 0 | 0 | 1.8072289 | 2.6449282 | CH25H;DDC;ALOX12 |
| 586 | growth (GO:0040007) | 5/329 | 0.2338375 | 1.0000000 | 0 | 0 | 1.5197568 | 2.2084028 | GJA1;NDRG4;ST6GAL2;DCX;EMP1 |
| 587 | monocarboxylic acid biosynthetic process (GO:0072330) | 3/167 | 0.2340613 | 1.0000000 | 0 | 0 | 1.7964072 | 2.6086929 | CH25H;PLA2G1B;ALOX12 |
| 588 | positive regulation of secretion by cell (GO:1903532) | 4/247 | 0.2347399 | 1.0000000 | 0 | 0 | 1.6194332 | 2.3470074 | KISS1;PLA2G1B;CRTAM;OR51E2 |
| 589 | secretion by cell (GO:0032940) | 6/415 | 0.2365598 | 1.0000000 | 0 | 0 | 1.4457831 | 2.0841749 | MC4R;SLC5A7;PROS1;CCL5;SLC6A13;SNCG |
| 590 | phosphatidylserine metabolic process (GO:0006658) | 1/27 | 0.2377921 | 1.0000000 | 0 | 0 | 3.7037037 | 5.3198467 | PLA2G1B |
| 591 | regulation of vascular permeability (GO:0043114) | 1/27 | 0.2377921 | 1.0000000 | 0 | 0 | 3.7037037 | 5.3198467 | RAMP2 |
| 592 | negative regulation of chemotaxis (GO:0050922) | 1/27 | 0.2377921 | 1.0000000 | 0 | 0 | 3.7037037 | 5.3198467 | ROBO2 |
| 593 | regulation of complement activation (GO:0030449) | 1/27 | 0.2377921 | 1.0000000 | 0 | 0 | 3.7037037 | 5.3198467 | PROS1 |
| 594 | negative regulation of interferon-gamma production (GO:0032689) | 1/27 | 0.2377921 | 1.0000000 | 0 | 0 | 3.7037037 | 5.3198467 | SCGB1A1 |
| 595 | regulation of vascular endothelial growth factor production (GO:0010574) | 1/27 | 0.2377921 | 1.0000000 | 0 | 0 | 3.7037037 | 5.3198467 | FLT4 |
| 596 | negative regulation of lymphocyte apoptotic process (GO:0070229) | 1/27 | 0.2377921 | 1.0000000 | 0 | 0 | 3.7037037 | 5.3198467 | CCL5 |
| 597 | regulation of platelet activation (GO:0010543) | 1/27 | 0.2377921 | 1.0000000 | 0 | 0 | 3.7037037 | 5.3198467 | ALOX12 |
| 598 | cellular response to fatty acid (GO:0071398) | 1/27 | 0.2377921 | 1.0000000 | 0 | 0 | 3.7037037 | 5.3198467 | OR51E2 |
| 599 | neurotransmitter metabolic process (GO:0042133) | 1/27 | 0.2377921 | 1.0000000 | 0 | 0 | 3.7037037 | 5.3198467 | SLC5A7 |
| 600 | positive regulation of cell-substrate adhesion (GO:0010811) | 2/93 | 0.2383085 | 1.0000000 | 0 | 0 | 2.1505376 | 3.0842782 | SMOC2;ECM2 |
| 601 | antigen processing and presentation of exogenous peptide antigen via MHC class II (GO:0019886) | 2/93 | 0.2383085 | 1.0000000 | 0 | 0 | 2.1505376 | 3.0842782 | HLA-DOA;HLA-DQB2 |
| 602 | regulation of metal ion transport (GO:0010959) | 4/250 | 0.2411890 | 1.0000000 | 0 | 0 | 1.6000000 | 2.2754791 | GJA1;PLA2G1B;CCL5;KCNJ1 |
| 603 | regulation of cell-cell adhesion (GO:0022407) | 2/94 | 0.2420055 | 1.0000000 | 0 | 0 | 2.1276596 | 3.0187127 | CCL5;ALOX12 |
| 604 | antigen processing and presentation of peptide antigen via MHC class II (GO:0002495) | 2/94 | 0.2420055 | 1.0000000 | 0 | 0 | 2.1276596 | 3.0187127 | HLA-DOA;HLA-DQB2 |
| 605 | regulation of lymphocyte proliferation (GO:0050670) | 3/170 | 0.2420212 | 1.0000000 | 0 | 0 | 1.7647059 | 2.5036409 | CCL5;SFTPD;SCGB1A1 |
| 606 | regulation of calcium ion transport (GO:0051924) | 3/171 | 0.2446846 | 1.0000000 | 0 | 0 | 1.7543860 | 2.4697984 | GJA1;PLA2G1B;CCL5 |
| 607 | antigen processing and presentation of exogenous peptide antigen (GO:0002478) | 3/171 | 0.2446846 | 1.0000000 | 0 | 0 | 1.7543860 | 2.4697984 | CD207;HLA-DOA;HLA-DQB2 |
| 608 | regulation of mononuclear cell proliferation (GO:0032944) | 3/171 | 0.2446846 | 1.0000000 | 0 | 0 | 1.7543860 | 2.4697984 | CCL5;SFTPD;SCGB1A1 |
| 609 | negative regulation of cytokine biosynthetic process (GO:0042036) | 1/28 | 0.2454244 | 1.0000000 | 0 | 0 | 3.5714286 | 5.0170219 | SFTPD |
| 610 | response to fluid shear stress (GO:0034405) | 1/28 | 0.2454244 | 1.0000000 | 0 | 0 | 3.5714286 | 5.0170219 | GJA1 |
| 611 | positive regulation of BMP signaling pathway (GO:0030513) | 1/28 | 0.2454244 | 1.0000000 | 0 | 0 | 3.5714286 | 5.0170219 | GPC3 |
| 612 | dopamine metabolic process (GO:0042417) | 1/28 | 0.2454244 | 1.0000000 | 0 | 0 | 3.5714286 | 5.0170219 | DDC |
| 613 | tissue regeneration (GO:0042246) | 1/28 | 0.2454244 | 1.0000000 | 0 | 0 | 3.5714286 | 5.0170219 | GJA1 |
| 614 | antimicrobial humoral response (GO:0019730) | 1/28 | 0.2454244 | 1.0000000 | 0 | 0 | 3.5714286 | 5.0170219 | PLA2G1B |
| 615 | rhythmic process (GO:0048511) | 4/252 | 0.2455112 | 1.0000000 | 0 | 0 | 1.5873016 | 2.2292267 | ROBO2;KISS1;DDC;HLF |
| 616 | regulation of lymphocyte mediated immunity (GO:0002706) | 2/95 | 0.2457050 | 1.0000000 | 0 | 0 | 2.1052632 | 2.9549968 | KLRK1;CRTAM |
| 617 | metal ion homeostasis (GO:0055065) | 6/422 | 0.2480835 | 1.0000000 | 0 | 0 | 1.4218009 | 1.9819764 | KISS1;CD52;GJA1;CCL5;KCNK3;ABCG2 |
| 618 | antigen processing and presentation of peptide or polysaccharide antigen via MHC class II (GO:0002504) | 2/96 | 0.2494068 | 1.0000000 | 0 | 0 | 2.0833333 | 2.8930625 | HLA-DOA;HLA-DQB2 |
| 619 | antigen processing and presentation of exogenous antigen (GO:0019884) | 3/173 | 0.2500255 | 1.0000000 | 0 | 0 | 1.7341040 | 2.4038017 | CD207;HLA-DOA;HLA-DQB2 |
| 620 | cellular response to heat (GO:0034605) | 1/29 | 0.2529808 | 1.0000000 | 0 | 0 | 3.4482759 | 4.7394545 | STAC |
| 621 | central nervous system neuron axonogenesis (GO:0021955) | 1/29 | 0.2529808 | 1.0000000 | 0 | 0 | 3.4482759 | 4.7394545 | DCX |
| 622 | response to pH (GO:0009268) | 1/29 | 0.2529808 | 1.0000000 | 0 | 0 | 3.4482759 | 4.7394545 | GJA1 |
| 623 | lipopolysaccharide-mediated signaling pathway (GO:0031663) | 1/29 | 0.2529808 | 1.0000000 | 0 | 0 | 3.4482759 | 4.7394545 | CCL5 |
| 624 | regulation of defense response to virus by virus (GO:0050690) | 1/29 | 0.2529808 | 1.0000000 | 0 | 0 | 3.4482759 | 4.7394545 | CD8B |
| 625 | positive regulation of cardiac muscle tissue development (GO:0055025) | 1/29 | 0.2529808 | 1.0000000 | 0 | 0 | 3.4482759 | 4.7394545 | FGF9 |
| 626 | regulation of protein activation cascade (GO:2000257) | 1/29 | 0.2529808 | 1.0000000 | 0 | 0 | 3.4482759 | 4.7394545 | PROS1 |
| 627 | cardiac muscle cell action potential involved in contraction (GO:0086002) | 1/29 | 0.2529808 | 1.0000000 | 0 | 0 | 3.4482759 | 4.7394545 | GJA1 |
| 628 | regulation of fibroblast growth factor receptor signaling pathway (GO:0040036) | 1/29 | 0.2529808 | 1.0000000 | 0 | 0 | 3.4482759 | 4.7394545 | HHIP |
| 629 | cerebral cortex cell migration (GO:0021795) | 1/29 | 0.2529808 | 1.0000000 | 0 | 0 | 3.4482759 | 4.7394545 | CX3CR1 |
| 630 | NAD metabolic process (GO:0019674) | 1/29 | 0.2529808 | 1.0000000 | 0 | 0 | 3.4482759 | 4.7394545 | QPRT |
| 631 | terpenoid metabolic process (GO:0006721) | 2/97 | 0.2531103 | 1.0000000 | 0 | 0 | 2.0618557 | 2.8328453 | OPN1SW;GPC3 |
| 632 | alcohol metabolic process (GO:0006066) | 5/340 | 0.2542695 | 1.0000000 | 0 | 0 | 1.4705882 | 2.0137658 | CH25H;ADH1C;ADH1B;PLA2G1B;LEPR |
| 633 | detection of external stimulus (GO:0009581) | 3/175 | 0.2553840 | 1.0000000 | 0 | 0 | 1.7142857 | 2.3399779 | OPN1SW;CNGA1;GPC3 |
| 634 | neuron projection morphogenesis (GO:0048812) | 3/175 | 0.2553840 | 1.0000000 | 0 | 0 | 1.7142857 | 2.3399779 | GPM6A;GJA1;DCX |
| 635 | osteoblast differentiation (GO:0001649) | 2/98 | 0.2568151 | 1.0000000 | 0 | 0 | 2.0408163 | 2.7742832 | GJA1;FGF9 |
| 636 | regulation of leukocyte proliferation (GO:0070663) | 3/176 | 0.2580694 | 1.0000000 | 0 | 0 | 1.7045455 | 2.3088527 | CCL5;SFTPD;SCGB1A1 |
| 637 | regulation of epithelial cell proliferation (GO:0050678) | 4/258 | 0.2585787 | 1.0000000 | 0 | 0 | 1.5503876 | 2.0969850 | KRT4;FGF9;FLT4;GPC3 |
| 638 | lens development in camera-type eye (GO:0002088) | 1/30 | 0.2604618 | 1.0000000 | 0 | 0 | 3.3333333 | 4.4843302 | GJA1 |
| 639 | hair follicle morphogenesis (GO:0031069) | 1/30 | 0.2604618 | 1.0000000 | 0 | 0 | 3.3333333 | 4.4843302 | TGM3 |
| 640 | endochondral ossification (GO:0001958) | 1/30 | 0.2604618 | 1.0000000 | 0 | 0 | 3.3333333 | 4.4843302 | FGF18 |
| 641 | positive regulation of multicellular organismal metabolic process (GO:0044253) | 1/30 | 0.2604618 | 1.0000000 | 0 | 0 | 3.3333333 | 4.4843302 | MC4R |
| 642 | embryonic hindlimb morphogenesis (GO:0035116) | 1/30 | 0.2604618 | 1.0000000 | 0 | 0 | 3.3333333 | 4.4843302 | GPC3 |
| 643 | central nervous system neuron development (GO:0021954) | 1/30 | 0.2604618 | 1.0000000 | 0 | 0 | 3.3333333 | 4.4843302 | ROBO2 |
| 644 | cardiac muscle cell action potential (GO:0086001) | 1/30 | 0.2604618 | 1.0000000 | 0 | 0 | 3.3333333 | 4.4843302 | GJA1 |
| 645 | positive regulation of glucose import (GO:0046326) | 1/30 | 0.2604618 | 1.0000000 | 0 | 0 | 3.3333333 | 4.4843302 | GPC3 |
| 646 | regulation of rhodopsin mediated signaling pathway (GO:0022400) | 1/30 | 0.2604618 | 1.0000000 | 0 | 0 | 3.3333333 | 4.4843302 | CNGA1 |
| 647 | axon extension (GO:0048675) | 1/30 | 0.2604618 | 1.0000000 | 0 | 0 | 3.3333333 | 4.4843302 | DCX |
| 648 | regulation of granulocyte chemotaxis (GO:0071622) | 1/30 | 0.2604618 | 1.0000000 | 0 | 0 | 3.3333333 | 4.4843302 | CCL5 |
| 649 | replacement ossification (GO:0036075) | 1/30 | 0.2604618 | 1.0000000 | 0 | 0 | 3.3333333 | 4.4843302 | FGF18 |
| 650 | neurotransmitter transport (GO:0006836) | 2/99 | 0.2605209 | 1.0000000 | 0 | 0 | 2.0202020 | 2.7173172 | SLC5A7;SLC6A13 |
| 651 | single organism cell adhesion (GO:0098602) | 4/259 | 0.2607703 | 1.0000000 | 0 | 0 | 1.5444015 | 2.0758538 | CCL5;ANXA9;JAM2;CDH7 |
| 652 | detection of abiotic stimulus (GO:0009582) | 3/178 | 0.2634516 | 1.0000000 | 0 | 0 | 1.6853933 | 2.2481220 | OPN1SW;CNGA1;GPC3 |
| 653 | cell-matrix adhesion (GO:0007160) | 2/100 | 0.2642273 | 1.0000000 | 0 | 0 | 2.0000000 | 2.6618910 | ECM2;PPFIA2 |
| 654 | unsaturated fatty acid metabolic process (GO:0033559) | 2/100 | 0.2642273 | 1.0000000 | 0 | 0 | 2.0000000 | 2.6618910 | PLA2G1B;ALOX12 |
| 655 | defense response to bacterium (GO:0042742) | 3/179 | 0.2661481 | 1.0000000 | 0 | 0 | 1.6759777 | 2.2184959 | PLA2G1B;SFTPD;BPI |
| 656 | positive regulation of leukocyte activation (GO:0002696) | 4/262 | 0.2673668 | 1.0000000 | 0 | 0 | 1.5267176 | 2.0139444 | KLRK1;CCL5;TRAC;HLA-DQB2 |
| 657 | regulation of response to wounding (GO:1903034) | 5/347 | 0.2674975 | 1.0000000 | 0 | 0 | 1.4409222 | 1.9000649 | PROS1;CCL5;SCGB1A1;ALOX12;HOPX |
| 658 | bicarbonate transport (GO:0015701) | 1/31 | 0.2678683 | 1.0000000 | 0 | 0 | 3.2258065 | 4.2492255 | SLC4A10 |
| 659 | phosphatidic acid biosynthetic process (GO:0006654) | 1/31 | 0.2678683 | 1.0000000 | 0 | 0 | 3.2258065 | 4.2492255 | PLA2G1B |
| 660 | positive regulation of blood pressure (GO:0045777) | 1/31 | 0.2678683 | 1.0000000 | 0 | 0 | 3.2258065 | 4.2492255 | OR51E2 |
| 661 | cellular response to alkaloid (GO:0071312) | 1/31 | 0.2678683 | 1.0000000 | 0 | 0 | 3.2258065 | 4.2492255 | DDC |
| 662 | regulation of endothelial cell apoptotic process (GO:2000351) | 1/31 | 0.2678683 | 1.0000000 | 0 | 0 | 3.2258065 | 4.2492255 | RAMP2 |
| 663 | regulation of meiosis (GO:0040020) | 1/31 | 0.2678683 | 1.0000000 | 0 | 0 | 3.2258065 | 4.2492255 | DMRT1 |
| 664 | regulation of Rho protein signal transduction (GO:0035023) | 1/31 | 0.2678683 | 1.0000000 | 0 | 0 | 3.2258065 | 4.2492255 | DLC1 |
| 665 | modification by host of symbiont morphology or physiology (GO:0051851) | 1/31 | 0.2678683 | 1.0000000 | 0 | 0 | 3.2258065 | 4.2492255 | CCL5 |
| 666 | phenol-containing compound biosynthetic process (GO:0046189) | 1/31 | 0.2678683 | 1.0000000 | 0 | 0 | 3.2258065 | 4.2492255 | DDC |
| 667 | regulation of smooth muscle cell migration (GO:0014910) | 1/31 | 0.2678683 | 1.0000000 | 0 | 0 | 3.2258065 | 4.2492255 | CCL5 |
| 668 | negative regulation of interleukin-6 production (GO:0032715) | 1/31 | 0.2678683 | 1.0000000 | 0 | 0 | 3.2258065 | 4.2492255 | BPI |
| 669 | protein kinase B signaling (GO:0043491) | 1/31 | 0.2678683 | 1.0000000 | 0 | 0 | 3.2258065 | 4.2492255 | CCL5 |
| 670 | phosphatidic acid metabolic process (GO:0046473) | 1/31 | 0.2678683 | 1.0000000 | 0 | 0 | 3.2258065 | 4.2492255 | PLA2G1B |
| 671 | regulation of collagen metabolic process (GO:0010712) | 1/31 | 0.2678683 | 1.0000000 | 0 | 0 | 3.2258065 | 4.2492255 | MFAP4 |
| 672 | peptide cross-linking (GO:0018149) | 1/31 | 0.2678683 | 1.0000000 | 0 | 0 | 3.2258065 | 4.2492255 | TGM3 |
| 673 | positive chemotaxis (GO:0050918) | 1/31 | 0.2678683 | 1.0000000 | 0 | 0 | 3.2258065 | 4.2492255 | CCL5 |
| 674 | tube morphogenesis (GO:0035239) | 2/101 | 0.2679339 | 1.0000000 | 0 | 0 | 1.9801980 | 2.6079506 | GJA1;GPC3 |
| 675 | taxis (GO:0042330) | 4/263 | 0.2695726 | 1.0000000 | 0 | 0 | 1.5209125 | 1.9937909 | CX3CR1;PLA2G1B;CCL5;SFTPD |
| 676 | chemotaxis (GO:0006935) | 4/263 | 0.2695726 | 1.0000000 | 0 | 0 | 1.5209125 | 1.9937909 | CX3CR1;PLA2G1B;CCL5;SFTPD |
| 677 | negative regulation of lymphocyte activation (GO:0051250) | 2/102 | 0.2716403 | 1.0000000 | 0 | 0 | 1.9607843 | 2.5554444 | SFTPD;SCGB1A1 |
| 678 | multi-organism localization (GO:1902579) | 1/32 | 0.2752010 | 1.0000000 | 0 | 0 | 3.1250000 | 4.0320428 | IFIT1 |
| 679 | negative regulation of striated muscle tissue development (GO:0045843) | 1/32 | 0.2752010 | 1.0000000 | 0 | 0 | 3.1250000 | 4.0320428 | GJA1 |
| 680 | positive regulation of protein tyrosine kinase activity (GO:0061098) | 1/32 | 0.2752010 | 1.0000000 | 0 | 0 | 3.1250000 | 4.0320428 | CCL5 |
| 681 | intracellular transport of virus (GO:0075733) | 1/32 | 0.2752010 | 1.0000000 | 0 | 0 | 3.1250000 | 4.0320428 | IFIT1 |
| 682 | multi-organism transport (GO:0044766) | 1/32 | 0.2752010 | 1.0000000 | 0 | 0 | 3.1250000 | 4.0320428 | IFIT1 |
| 683 | multi-organism intracellular transport (GO:1902583) | 1/32 | 0.2752010 | 1.0000000 | 0 | 0 | 3.1250000 | 4.0320428 | IFIT1 |
| 684 | regulation of potassium ion transmembrane transport (GO:1901379) | 1/32 | 0.2752010 | 1.0000000 | 0 | 0 | 3.1250000 | 4.0320428 | KCNJ1 |
| 685 | multicellular organismal water homeostasis (GO:0050891) | 1/32 | 0.2752010 | 1.0000000 | 0 | 0 | 3.1250000 | 4.0320428 | ALOX12 |
| 686 | negative regulation of cytokine-mediated signaling pathway (GO:0001960) | 1/32 | 0.2752010 | 1.0000000 | 0 | 0 | 3.1250000 | 4.0320428 | CCL5 |
| 687 | transport of virus (GO:0046794) | 1/32 | 0.2752010 | 1.0000000 | 0 | 0 | 3.1250000 | 4.0320428 | IFIT1 |
| 688 | negative regulation of cAMP biosynthetic process (GO:0030818) | 1/32 | 0.2752010 | 1.0000000 | 0 | 0 | 3.1250000 | 4.0320428 | GABBR2 |
| 689 | superoxide metabolic process (GO:0006801) | 1/32 | 0.2752010 | 1.0000000 | 0 | 0 | 3.1250000 | 4.0320428 | ALOX12 |
| 690 | response to pain (GO:0048265) | 1/32 | 0.2752010 | 1.0000000 | 0 | 0 | 3.1250000 | 4.0320428 | GRIK1 |
| 691 | regulation of synaptic transmission, GABAergic (GO:0032228) | 1/32 | 0.2752010 | 1.0000000 | 0 | 0 | 3.1250000 | 4.0320428 | GRIK1 |
| 692 | regulation of lymphocyte migration (GO:2000401) | 1/32 | 0.2752010 | 1.0000000 | 0 | 0 | 3.1250000 | 4.0320428 | CCL5 |
| 693 | regulation of T cell apoptotic process (GO:0070232) | 1/32 | 0.2752010 | 1.0000000 | 0 | 0 | 3.1250000 | 4.0320428 | CCL5 |
| 694 | regulation of transforming growth factor beta receptor signaling pathway (GO:0017015) | 2/103 | 0.2753461 | 1.0000000 | 0 | 0 | 1.9417476 | 2.5043233 | PEG10;FBN1 |
| 695 | cellular response to fibroblast growth factor stimulus (GO:0044344) | 3/183 | 0.2769660 | 1.0000000 | 0 | 0 | 1.6393443 | 2.1046893 | FGF9;CCL5;FGF18 |
| 696 | antigen processing and presentation of peptide antigen (GO:0048002) | 3/185 | 0.2823919 | 1.0000000 | 0 | 0 | 1.6216216 | 2.0504748 | CD207;HLA-DOA;HLA-DQB2 |
| 697 | negative regulation of cytokine production (GO:0001818) | 3/185 | 0.2823919 | 1.0000000 | 0 | 0 | 1.6216216 | 2.0504748 | SFTPD;SCGB1A1;BPI |
| 698 | peptide hormone processing (GO:0016486) | 1/33 | 0.2824605 | 1.0000000 | 0 | 0 | 3.0303030 | 3.8309588 | SCG5 |
| 699 | positive regulation of reproductive process (GO:2000243) | 1/33 | 0.2824605 | 1.0000000 | 0 | 0 | 3.0303030 | 3.8309588 | DMRT1 |
| 700 | histone deacetylation (GO:0016575) | 1/33 | 0.2824605 | 1.0000000 | 0 | 0 | 3.0303030 | 3.8309588 | HOPX |
| 701 | interaction with symbiont (GO:0051702) | 1/33 | 0.2824605 | 1.0000000 | 0 | 0 | 3.0303030 | 3.8309588 | CCL5 |
| 702 | regulation of bone resorption (GO:0045124) | 1/33 | 0.2824605 | 1.0000000 | 0 | 0 | 3.0303030 | 3.8309588 | MC4R |
| 703 | response to progesterone (GO:0032570) | 1/33 | 0.2824605 | 1.0000000 | 0 | 0 | 3.0303030 | 3.8309588 | RAMP2 |
| 704 | rhodopsin mediated signaling pathway (GO:0016056) | 1/33 | 0.2824605 | 1.0000000 | 0 | 0 | 3.0303030 | 3.8309588 | CNGA1 |
| 705 | negative regulation of cyclic nucleotide biosynthetic process (GO:0030803) | 1/33 | 0.2824605 | 1.0000000 | 0 | 0 | 3.0303030 | 3.8309588 | GABBR2 |
| 706 | negative regulation of muscle tissue development (GO:1901862) | 1/33 | 0.2824605 | 1.0000000 | 0 | 0 | 3.0303030 | 3.8309588 | GJA1 |
| 707 | positive regulation of ion transport (GO:0043270) | 3/186 | 0.2851085 | 1.0000000 | 0 | 0 | 1.6129032 | 2.0240089 | PLA2G1B;CCL5;GRIK1 |
| 708 | immune response-regulating cell surface receptor signaling pathway (GO:0002768) | 6/444 | 0.2852710 | 1.0000000 | 0 | 0 | 1.3513514 | 1.6950213 | IGHG4;FGF9;TRAC;FGF18;SKAP1;HLA-DQB2 |
| 709 | skeletal system morphogenesis (GO:0048705) | 2/106 | 0.2864567 | 1.0000000 | 0 | 0 | 1.8867925 | 2.3588071 | HHIP;TBX4 |
| 710 | response to transition metal nanoparticle (GO:1990267) | 2/106 | 0.2864567 | 1.0000000 | 0 | 0 | 1.8867925 | 2.3588071 | KCNK3;ABCG2 |
| 711 | brain development (GO:0007420) | 3/187 | 0.2878273 | 1.0000000 | 0 | 0 | 1.6042781 | 1.9979593 | ROBO2;DCX;KCNK3 |
| 712 | organic acid biosynthetic process (GO:0016053) | 4/272 | 0.2895615 | 1.0000000 | 0 | 0 | 1.4705882 | 1.8226289 | CH25H;PLA2G1B;PADI3;ALOX12 |
| 713 | carboxylic acid biosynthetic process (GO:0046394) | 4/272 | 0.2895615 | 1.0000000 | 0 | 0 | 1.4705882 | 1.8226289 | CH25H;PLA2G1B;PADI3;ALOX12 |
| 714 | positive regulation of defense response (GO:0031349) | 4/272 | 0.2895615 | 1.0000000 | 0 | 0 | 1.4705882 | 1.8226289 | GJA1;KLRK1;CCL5;CRTAM |
| 715 | positive regulation of cell activation (GO:0050867) | 4/272 | 0.2895615 | 1.0000000 | 0 | 0 | 1.4705882 | 1.8226289 | KLRK1;CCL5;TRAC;HLA-DQB2 |
| 716 | dendrite morphogenesis (GO:0048813) | 1/34 | 0.2896478 | 1.0000000 | 0 | 0 | 2.9411765 | 3.6443812 | DCX |
| 717 | negative regulation of muscle organ development (GO:0048635) | 1/34 | 0.2896478 | 1.0000000 | 0 | 0 | 2.9411765 | 3.6443812 | GJA1 |
| 718 | negative regulation of reproductive process (GO:2000242) | 1/34 | 0.2896478 | 1.0000000 | 0 | 0 | 2.9411765 | 3.6443812 | NPPC |
| 719 | response to cocaine (GO:0042220) | 1/34 | 0.2896478 | 1.0000000 | 0 | 0 | 2.9411765 | 3.6443812 | SNCG |
| 720 | negative regulation of tumor necrosis factor production (GO:0032720) | 1/34 | 0.2896478 | 1.0000000 | 0 | 0 | 2.9411765 | 3.6443812 | BPI |
| 721 | phosphatidylglycerol metabolic process (GO:0046471) | 1/34 | 0.2896478 | 1.0000000 | 0 | 0 | 2.9411765 | 3.6443812 | PLA2G1B |
| 722 | negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway (GO:0090101) | 2/107 | 0.2901569 | 1.0000000 | 0 | 0 | 1.8691589 | 2.3127732 | PEG10;FBN1 |
| 723 | cholesterol metabolic process (GO:0008203) | 2/107 | 0.2901569 | 1.0000000 | 0 | 0 | 1.8691589 | 2.3127732 | CH25H;LEPR |
| 724 | positive regulation of behavior (GO:0048520) | 2/107 | 0.2901569 | 1.0000000 | 0 | 0 | 1.8691589 | 2.3127732 | GJA1;CCL5 |
| 725 | positive regulation of growth (GO:0045927) | 3/189 | 0.2932710 | 1.0000000 | 0 | 0 | 1.5873016 | 1.9470766 | FGF9;ALOX12;HOPX |
| 726 | inorganic anion transmembrane transport (GO:0098661) | 2/108 | 0.2938547 | 1.0000000 | 0 | 0 | 1.8518519 | 2.2679071 | GABRD;CLCA4 |
| 727 | positive regulation of innate immune response (GO:0045089) | 3/190 | 0.2959955 | 1.0000000 | 0 | 0 | 1.5789474 | 1.9222277 | KLRK1;CCL5;CRTAM |
| 728 | dendrite development (GO:0016358) | 1/35 | 0.2967634 | 1.0000000 | 0 | 0 | 2.8571429 | 3.4709146 | FEZF2 |
| 729 | positive regulation of glucose transport (GO:0010828) | 1/35 | 0.2967634 | 1.0000000 | 0 | 0 | 2.8571429 | 3.4709146 | GPC3 |
| 730 | insulin secretion (GO:0030073) | 1/35 | 0.2967634 | 1.0000000 | 0 | 0 | 2.8571429 | 3.4709146 | MC4R |
| 731 | regulation of antigen receptor-mediated signaling pathway (GO:0050854) | 1/35 | 0.2967634 | 1.0000000 | 0 | 0 | 2.8571429 | 3.4709146 | UBASH3A |
| 732 | negative regulation of purine nucleotide biosynthetic process (GO:1900372) | 1/35 | 0.2967634 | 1.0000000 | 0 | 0 | 2.8571429 | 3.4709146 | GABBR2 |
| 733 | myeloid cell activation involved in immune response (GO:0002275) | 1/35 | 0.2967634 | 1.0000000 | 0 | 0 | 2.8571429 | 3.4709146 | CX3CR1 |
| 734 | alditol phosphate metabolic process (GO:0052646) | 1/35 | 0.2967634 | 1.0000000 | 0 | 0 | 2.8571429 | 3.4709146 | PLA2G1B |
| 735 | regulation of filopodium assembly (GO:0051489) | 1/35 | 0.2967634 | 1.0000000 | 0 | 0 | 2.8571429 | 3.4709146 | GPM6A |
| 736 | metanephros development (GO:0001656) | 1/35 | 0.2967634 | 1.0000000 | 0 | 0 | 2.8571429 | 3.4709146 | ROBO2 |
| 737 | negative regulation of tumor necrosis factor superfamily cytokine production (GO:1903556) | 1/35 | 0.2967634 | 1.0000000 | 0 | 0 | 2.8571429 | 3.4709146 | BPI |
| 738 | embryonic skeletal system development (GO:0048706) | 1/35 | 0.2967634 | 1.0000000 | 0 | 0 | 2.8571429 | 3.4709146 | FGF9 |
| 739 | neuron projection extension (GO:1990138) | 1/35 | 0.2967634 | 1.0000000 | 0 | 0 | 2.8571429 | 3.4709146 | DCX |
| 740 | positive regulation of phagocytosis (GO:0050766) | 1/35 | 0.2967634 | 1.0000000 | 0 | 0 | 2.8571429 | 3.4709146 | SFTPD |
| 741 | negative regulation of extrinsic apoptotic signaling pathway in absence of ligand (GO:2001240) | 1/35 | 0.2967634 | 1.0000000 | 0 | 0 | 2.8571429 | 3.4709146 | CX3CR1 |
| 742 | negative regulation of signal transduction in absence of ligand (GO:1901099) | 1/35 | 0.2967634 | 1.0000000 | 0 | 0 | 2.8571429 | 3.4709146 | CX3CR1 |
| 743 | cAMP metabolic process (GO:0046058) | 1/35 | 0.2967634 | 1.0000000 | 0 | 0 | 2.8571429 | 3.4709146 | RAMP2 |
| 744 | negative regulation of nucleotide biosynthetic process (GO:0030809) | 1/35 | 0.2967634 | 1.0000000 | 0 | 0 | 2.8571429 | 3.4709146 | GABBR2 |
| 745 | negative regulation of ERK1 and ERK2 cascade (GO:0070373) | 1/35 | 0.2967634 | 1.0000000 | 0 | 0 | 2.8571429 | 3.4709146 | DUSP26 |
| 746 | cellular chemical homeostasis (GO:0055082) | 6/452 | 0.2990968 | 1.0000000 | 0 | 0 | 1.3274336 | 1.6021964 | KISS1;CD52;GJA1;CCL5;KCNK3;ABCG2 |
| 747 | negative regulation of epithelial cell proliferation (GO:0050680) | 2/110 | 0.3012423 | 1.0000000 | 0 | 0 | 1.8181818 | 2.1815278 | KRT4;GPC3 |
| 748 | cellular response to lipopolysaccharide (GO:0071222) | 2/110 | 0.3012423 | 1.0000000 | 0 | 0 | 1.8181818 | 2.1815278 | CX3CR1;CCL5 |
| 749 | regulation of gluconeogenesis (GO:0006111) | 1/36 | 0.3038081 | 1.0000000 | 0 | 0 | 2.7777778 | 3.3093308 | LEPR |
| 750 | regulation of cell adhesion mediated by integrin (GO:0033628) | 1/36 | 0.3038081 | 1.0000000 | 0 | 0 | 2.7777778 | 3.3093308 | CCL5 |
| 751 | negative regulation of response to cytokine stimulus (GO:0060761) | 1/36 | 0.3038081 | 1.0000000 | 0 | 0 | 2.7777778 | 3.3093308 | CCL5 |
| 752 | regulation of catecholamine secretion (GO:0050433) | 1/36 | 0.3038081 | 1.0000000 | 0 | 0 | 2.7777778 | 3.3093308 | SNCG |
| 753 | negative regulation of cellular carbohydrate metabolic process (GO:0010677) | 1/36 | 0.3038081 | 1.0000000 | 0 | 0 | 2.7777778 | 3.3093308 | LEPR |
| 754 | placenta development (GO:0001890) | 1/36 | 0.3038081 | 1.0000000 | 0 | 0 | 2.7777778 | 3.3093308 | PEG10 |
| 755 | negative regulation of cAMP metabolic process (GO:0030815) | 1/36 | 0.3038081 | 1.0000000 | 0 | 0 | 2.7777778 | 3.3093308 | GABBR2 |
| 756 | chromosome organization involved in meiosis (GO:0070192) | 1/36 | 0.3038081 | 1.0000000 | 0 | 0 | 2.7777778 | 3.3093308 | MEIOB |
| 757 | positive regulation of organ growth (GO:0046622) | 1/36 | 0.3038081 | 1.0000000 | 0 | 0 | 2.7777778 | 3.3093308 | FGF9 |
| 758 | protein deacetylation (GO:0006476) | 1/36 | 0.3038081 | 1.0000000 | 0 | 0 | 2.7777778 | 3.3093308 | HOPX |
| 759 | response to alkaloid (GO:0043279) | 2/111 | 0.3049314 | 1.0000000 | 0 | 0 | 1.8018018 | 2.1399429 | DDC;SNCG |
| 760 | positive regulation of cysteine-type endopeptidase activity involved in apoptotic process (GO:0043280) | 2/111 | 0.3049314 | 1.0000000 | 0 | 0 | 1.8018018 | 2.1399429 | DLC1;ALOX12 |
| 761 | synapse organization (GO:0050808) | 2/111 | 0.3049314 | 1.0000000 | 0 | 0 | 1.8018018 | 2.1399429 | GPM6A;SNCG |
| 762 | positive regulation of cell migration (GO:0030335) | 4/280 | 0.3074995 | 1.0000000 | 0 | 0 | 1.4285714 | 1.6846883 | FLT4;CCL5;ALOX12;GPR124 |
| 763 | regulation of striated muscle tissue development (GO:0016202) | 2/112 | 0.3086171 | 1.0000000 | 0 | 0 | 1.7857143 | 2.0993823 | GJA1;FGF9 |
| 764 | cellular response to insulin stimulus (GO:0032869) | 3/195 | 0.3096393 | 1.0000000 | 0 | 0 | 1.5384615 | 1.8036111 | FGF9;PLA2G1B;FGF18 |
| 765 | positive regulation of mesenchymal cell proliferation (GO:0002053) | 1/37 | 0.3107825 | 1.0000000 | 0 | 0 | 2.7027027 | 3.1585455 | FGF9 |
| 766 | anterior/posterior axis specification (GO:0009948) | 1/37 | 0.3107825 | 1.0000000 | 0 | 0 | 2.7027027 | 3.1585455 | GPC3 |
| 767 | positive regulation of calcium ion transport into cytosol (GO:0010524) | 1/37 | 0.3107825 | 1.0000000 | 0 | 0 | 2.7027027 | 3.1585455 | PLA2G1B |
| 768 | negative regulation of cyclic nucleotide metabolic process (GO:0030800) | 1/37 | 0.3107825 | 1.0000000 | 0 | 0 | 2.7027027 | 3.1585455 | GABBR2 |
| 769 | regulation of muscle tissue development (GO:1901861) | 2/113 | 0.3122988 | 1.0000000 | 0 | 0 | 1.7699115 | 2.0598136 | GJA1;FGF9 |
| 770 | regulation of muscle organ development (GO:0048634) | 2/114 | 0.3159765 | 1.0000000 | 0 | 0 | 1.7543860 | 2.0212059 | GJA1;FGF9 |
| 771 | isoprenoid metabolic process (GO:0006720) | 2/114 | 0.3159765 | 1.0000000 | 0 | 0 | 1.7543860 | 2.0212059 | OPN1SW;GPC3 |
| 772 | cellular response to hormone stimulus (GO:0032870) | 6/462 | 0.3165564 | 1.0000000 | 0 | 0 | 1.2987013 | 1.4938364 | ROBO2;RAMP2;FGF9;PLA2G1B;FGF18;OR51E2 |
| 773 | negative regulation of Ras protein signal transduction (GO:0046580) | 1/38 | 0.3176875 | 1.0000000 | 0 | 0 | 2.6315789 | 3.0175977 | DLC1 |
| 774 | anion homeostasis (GO:0055081) | 1/38 | 0.3176875 | 1.0000000 | 0 | 0 | 2.6315789 | 3.0175977 | FABP3 |
| 775 | regulation of muscle cell apoptotic process (GO:0010660) | 1/38 | 0.3176875 | 1.0000000 | 0 | 0 | 2.6315789 | 3.0175977 | ALOX12 |
| 776 | water homeostasis (GO:0030104) | 1/38 | 0.3176875 | 1.0000000 | 0 | 0 | 2.6315789 | 3.0175977 | ALOX12 |
| 777 | hindlimb morphogenesis (GO:0035137) | 1/38 | 0.3176875 | 1.0000000 | 0 | 0 | 2.6315789 | 3.0175977 | GPC3 |
| 778 | leukocyte activation (GO:0045321) | 5/373 | 0.3177926 | 1.0000000 | 0 | 0 | 1.3404826 | 1.5366707 | CX3CR1;KLRK1;CD8B;CCL5;CRTAM |
| 779 | negative regulation of cell adhesion (GO:0007162) | 2/115 | 0.3196498 | 1.0000000 | 0 | 0 | 1.7391304 | 1.9835291 | ALOX12;JAM2 |
| 780 | positive regulation of ERK1 and ERK2 cascade (GO:0070374) | 2/115 | 0.3196498 | 1.0000000 | 0 | 0 | 1.7391304 | 1.9835291 | FLT4;FGF18 |
| 781 | positive regulation of cell motility (GO:2000147) | 4/287 | 0.3232894 | 1.0000000 | 0 | 0 | 1.3937282 | 1.5738081 | FLT4;CCL5;ALOX12;GPR124 |
| 782 | cellular response to molecule of bacterial origin (GO:0071219) | 2/116 | 0.3233184 | 1.0000000 | 0 | 0 | 1.7241379 | 1.9467545 | CX3CR1;CCL5 |
| 783 | ossification (GO:0001503) | 2/116 | 0.3233184 | 1.0000000 | 0 | 0 | 1.7241379 | 1.9467545 | NPPC;FGF18 |
| 784 | social behavior (GO:0035176) | 1/39 | 0.3245236 | 1.0000000 | 0 | 0 | 2.5641026 | 2.8856335 | GRID1 |
| 785 | heart morphogenesis (GO:0003007) | 1/39 | 0.3245236 | 1.0000000 | 0 | 0 | 2.5641026 | 2.8856335 | DLC1 |
| 786 | positive regulation of cell-cell adhesion (GO:0022409) | 1/39 | 0.3245236 | 1.0000000 | 0 | 0 | 2.5641026 | 2.8856335 | CCL5 |
| 787 | bone mineralization (GO:0030282) | 1/39 | 0.3245236 | 1.0000000 | 0 | 0 | 2.5641026 | 2.8856335 | GPC3 |
| 788 | bile acid metabolic process (GO:0008206) | 1/39 | 0.3245236 | 1.0000000 | 0 | 0 | 2.5641026 | 2.8856335 | CH25H |
| 789 | positive regulation of striated muscle cell differentiation (GO:0051155) | 1/39 | 0.3245236 | 1.0000000 | 0 | 0 | 2.5641026 | 2.8856335 | HOPX |
| 790 | intraspecies interaction between organisms (GO:0051703) | 1/39 | 0.3245236 | 1.0000000 | 0 | 0 | 2.5641026 | 2.8856335 | GRID1 |
| 791 | embryo implantation (GO:0007566) | 1/39 | 0.3245236 | 1.0000000 | 0 | 0 | 2.5641026 | 2.8856335 | SCGB1A1 |
| 792 | tight junction assembly (GO:0070830) | 1/39 | 0.3245236 | 1.0000000 | 0 | 0 | 2.5641026 | 2.8856335 | RAMP2 |
| 793 | protein deacylation (GO:0035601) | 1/39 | 0.3245236 | 1.0000000 | 0 | 0 | 2.5641026 | 2.8856335 | HOPX |
| 794 | negative regulation of small GTPase mediated signal transduction (GO:0051058) | 1/39 | 0.3245236 | 1.0000000 | 0 | 0 | 2.5641026 | 2.8856335 | DLC1 |
| 795 | sterol biosynthetic process (GO:0016126) | 1/39 | 0.3245236 | 1.0000000 | 0 | 0 | 2.5641026 | 2.8856335 | CH25H |
| 796 | response to bacterium (GO:0009617) | 3/201 | 0.3260385 | 1.0000000 | 0 | 0 | 1.4925373 | 1.6727460 | PLA2G1B;SFTPD;BPI |
| 797 | secondary metabolic process (GO:0019748) | 1/40 | 0.3312915 | 1.0000000 | 0 | 0 | 2.5000000 | 2.7618913 | DDC |
| 798 | negative regulation of BMP signaling pathway (GO:0030514) | 1/40 | 0.3312915 | 1.0000000 | 0 | 0 | 2.5000000 | 2.7618913 | FBN1 |
| 799 | ureteric bud development (GO:0001657) | 1/40 | 0.3312915 | 1.0000000 | 0 | 0 | 2.5000000 | 2.7618913 | ROBO2 |
| 800 | cellular response to cytokine stimulus (GO:0071345) | 6/471 | 0.3324065 | 1.0000000 | 0 | 0 | 1.2738854 | 1.4030529 | CX3CR1;CCL5;LEPR;IFIT1;HLA-DQB2;OASL |
| 801 | negative regulation of locomotion (GO:0040013) | 3/204 | 0.3342400 | 1.0000000 | 0 | 0 | 1.4705882 | 1.6116117 | ROBO2;CX3CR1;DLC1 |
| 802 | sterol metabolic process (GO:0016125) | 2/119 | 0.3342935 | 1.0000000 | 0 | 0 | 1.6806723 | 1.8415730 | CH25H;LEPR |
| 803 | positive regulation of cysteine-type endopeptidase activity (GO:2001056) | 2/119 | 0.3342935 | 1.0000000 | 0 | 0 | 1.6806723 | 1.8415730 | DLC1;ALOX12 |
| 804 | regulation of leukocyte mediated immunity (GO:0002703) | 2/120 | 0.3379407 | 1.0000000 | 0 | 0 | 1.6666667 | 1.8081412 | KLRK1;CRTAM |
| 805 | positive regulation of cell division (GO:0051781) | 2/120 | 0.3379407 | 1.0000000 | 0 | 0 | 1.6666667 | 1.8081412 | FGF9;DMRT1 |
| 806 | macromolecule deacylation (GO:0098732) | 1/41 | 0.3379920 | 1.0000000 | 0 | 0 | 2.4390244 | 2.6456903 | HOPX |
| 807 | negative regulation of cell-cell adhesion (GO:0022408) | 1/41 | 0.3379920 | 1.0000000 | 0 | 0 | 2.4390244 | 2.6456903 | ALOX12 |
| 808 | cell-substrate junction assembly (GO:0007044) | 1/41 | 0.3379920 | 1.0000000 | 0 | 0 | 2.4390244 | 2.6456903 | DLC1 |
| 809 | response to exogenous dsRNA (GO:0043330) | 1/41 | 0.3379920 | 1.0000000 | 0 | 0 | 2.4390244 | 2.6456903 | IFIT1 |
| 810 | T cell proliferation (GO:0042098) | 1/41 | 0.3379920 | 1.0000000 | 0 | 0 | 2.4390244 | 2.6456903 | CRTAM |
| 811 | negative regulation of leukocyte apoptotic process (GO:2000107) | 1/41 | 0.3379920 | 1.0000000 | 0 | 0 | 2.4390244 | 2.6456903 | CCL5 |
| 812 | regulation of synapse assembly (GO:0051963) | 1/41 | 0.3379920 | 1.0000000 | 0 | 0 | 2.4390244 | 2.6456903 | ROBO2 |
| 813 | oligosaccharide metabolic process (GO:0009311) | 1/41 | 0.3379920 | 1.0000000 | 0 | 0 | 2.4390244 | 2.6456903 | ST6GAL2 |
| 814 | regulation of chondrocyte differentiation (GO:0032330) | 1/41 | 0.3379920 | 1.0000000 | 0 | 0 | 2.4390244 | 2.6456903 | FGF18 |
| 815 | response to zinc ion (GO:0010043) | 1/41 | 0.3379920 | 1.0000000 | 0 | 0 | 2.4390244 | 2.6456903 | KCNK3 |
| 816 | positive regulation of wound healing (GO:0090303) | 1/41 | 0.3379920 | 1.0000000 | 0 | 0 | 2.4390244 | 2.6456903 | HOPX |
| 817 | multi-multicellular organism process (GO:0044706) | 2/121 | 0.3415820 | 1.0000000 | 0 | 0 | 1.6528926 | 1.7754835 | RAMP2;SCGB1A1 |
| 818 | morphogenesis of an epithelium (GO:0002009) | 4/296 | 0.3436708 | 1.0000000 | 0 | 0 | 1.3513514 | 1.4433392 | GJA1;HHIP;GPC3;TBX4 |
| 819 | positive regulation of cellular component movement (GO:0051272) | 4/296 | 0.3436708 | 1.0000000 | 0 | 0 | 1.3513514 | 1.4433392 | FLT4;CCL5;ALOX12;GPR124 |
| 820 | positive regulation of mitosis (GO:0045840) | 1/42 | 0.3446257 | 1.0000000 | 0 | 0 | 2.3809524 | 2.5364201 | DMRT1 |
| 821 | nucleotide biosynthetic process (GO:0009165) | 3/208 | 0.3451691 | 1.0000000 | 0 | 0 | 1.4423077 | 1.5342129 | NPPC;RAMP2;QPRT |
| 822 | regulation of lipase activity (GO:0060191) | 2/122 | 0.3452170 | 1.0000000 | 0 | 0 | 1.6393443 | 1.7435771 | PLA2G1B;CCL5 |
| 823 | nucleoside phosphate biosynthetic process (GO:1901293) | 3/209 | 0.3478993 | 1.0000000 | 0 | 0 | 1.4354067 | 1.5155629 | NPPC;RAMP2;QPRT |
| 824 | positive regulation of multi-organism process (GO:0043902) | 2/123 | 0.3488456 | 1.0000000 | 0 | 0 | 1.6260163 | 1.7123999 | CCL5;IFIT1 |
| 825 | cell killing (GO:0001906) | 1/43 | 0.3511932 | 1.0000000 | 0 | 0 | 2.3255814 | 2.4335320 | CRTAM |
| 826 | catechol-containing compound metabolic process (GO:0009712) | 1/43 | 0.3511932 | 1.0000000 | 0 | 0 | 2.3255814 | 2.4335320 | DDC |
| 827 | regulation of mesenchymal cell proliferation (GO:0010464) | 1/43 | 0.3511932 | 1.0000000 | 0 | 0 | 2.3255814 | 2.4335320 | FGF9 |
| 828 | receptor internalization (GO:0031623) | 1/43 | 0.3511932 | 1.0000000 | 0 | 0 | 2.3255814 | 2.4335320 | RAMP2 |
| 829 | negative regulation of carbohydrate metabolic process (GO:0045912) | 1/43 | 0.3511932 | 1.0000000 | 0 | 0 | 2.3255814 | 2.4335320 | LEPR |
| 830 | catecholamine metabolic process (GO:0006584) | 1/43 | 0.3511932 | 1.0000000 | 0 | 0 | 2.3255814 | 2.4335320 | DDC |
| 831 | regulation of organic acid transport (GO:0032890) | 1/43 | 0.3511932 | 1.0000000 | 0 | 0 | 2.3255814 | 2.4335320 | GRIK1 |
| 832 | carbohydrate derivative transport (GO:1901264) | 1/43 | 0.3511932 | 1.0000000 | 0 | 0 | 2.3255814 | 2.4335320 | GJA1 |
| 833 | regulation of cytokine production (GO:0001817) | 6/482 | 0.3519100 | 1.0000000 | 0 | 0 | 1.2448133 | 1.3000578 | FLT4;SFTPD;CRTAM;SCGB1A1;BPI;UBASH3A |
| 834 | cellular biogenic amine metabolic process (GO:0006576) | 2/125 | 0.3560824 | 1.0000000 | 0 | 0 | 1.6000000 | 1.6521490 | DDC;PLA2G1B |
| 835 | cellular amine metabolic process (GO:0044106) | 2/125 | 0.3560824 | 1.0000000 | 0 | 0 | 1.6000000 | 1.6521490 | DDC;PLA2G1B |
| 836 | vasculature development (GO:0001944) | 1/44 | 0.3576952 | 1.0000000 | 0 | 0 | 2.2727273 | 2.3365317 | FLT4 |
| 837 | neutrophil chemotaxis (GO:0030593) | 1/44 | 0.3576952 | 1.0000000 | 0 | 0 | 2.2727273 | 2.3365317 | PLA2G1B |
| 838 | branching involved in ureteric bud morphogenesis (GO:0001658) | 1/44 | 0.3576952 | 1.0000000 | 0 | 0 | 2.2727273 | 2.3365317 | GPC3 |
| 839 | mesonephric tubule development (GO:0072164) | 1/44 | 0.3576952 | 1.0000000 | 0 | 0 | 2.2727273 | 2.3365317 | ROBO2 |
| 840 | epithelial cell differentiation (GO:0030855) | 4/303 | 0.3595502 | 1.0000000 | 0 | 0 | 1.3201320 | 1.3503648 | SCUBE1;KRT4;DMRT1;TGM3 |
| 841 | purine ribonucleotide biosynthetic process (GO:0009152) | 2/126 | 0.3596902 | 1.0000000 | 0 | 0 | 1.5873016 | 1.6230353 | NPPC;RAMP2 |
| 842 | negative regulation of Wnt signaling pathway (GO:0030178) | 2/126 | 0.3596902 | 1.0000000 | 0 | 0 | 1.5873016 | 1.6230353 | FGF9;GPC3 |
| 843 | cellular response to radiation (GO:0071478) | 2/126 | 0.3596902 | 1.0000000 | 0 | 0 | 1.5873016 | 1.6230353 | MFAP4;CNGA1 |
| 844 | regulation of Wnt signaling pathway (GO:0030111) | 3/214 | 0.3615322 | 1.0000000 | 0 | 0 | 1.4018692 | 1.4262677 | FGF9;GPC3;LGR5 |
| 845 | positive regulation of locomotion (GO:0040017) | 4/304 | 0.3618189 | 1.0000000 | 0 | 0 | 1.3157895 | 1.3376467 | FLT4;CCL5;ALOX12;GPR124 |
| 846 | mesonephric epithelium development (GO:0072163) | 1/45 | 0.3641324 | 1.0000000 | 0 | 0 | 2.2222222 | 2.2449725 | ROBO2 |
| 847 | regulation of interleukin-2 production (GO:0032663) | 1/45 | 0.3641324 | 1.0000000 | 0 | 0 | 2.2222222 | 2.2449725 | SFTPD |
| 848 | regulation of humoral immune response (GO:0002920) | 1/45 | 0.3641324 | 1.0000000 | 0 | 0 | 2.2222222 | 2.2449725 | PROS1 |
| 849 | substantia nigra development (GO:0021762) | 1/45 | 0.3641324 | 1.0000000 | 0 | 0 | 2.2222222 | 2.2449725 | FGF9 |
| 850 | cellular response to interleukin-1 (GO:0071347) | 1/45 | 0.3641324 | 1.0000000 | 0 | 0 | 2.2222222 | 2.2449725 | CCL5 |
| 851 | excretion (GO:0007588) | 1/45 | 0.3641324 | 1.0000000 | 0 | 0 | 2.2222222 | 2.2449725 | KCNJ1 |
| 852 | neutrophil migration (GO:1990266) | 1/45 | 0.3641324 | 1.0000000 | 0 | 0 | 2.2222222 | 2.2449725 | PLA2G1B |
| 853 | calcium ion transport (GO:0006816) | 3/215 | 0.3642542 | 1.0000000 | 0 | 0 | 1.3953488 | 1.4091675 | GPM6A;RAMP2;CCL5 |
| 854 | positive regulation of endopeptidase activity (GO:0010950) | 2/128 | 0.3668834 | 1.0000000 | 0 | 0 | 1.5625000 | 1.5667361 | DLC1;ALOX12 |
| 855 | regulation of protein binding (GO:0043393) | 2/128 | 0.3668834 | 1.0000000 | 0 | 0 | 1.5625000 | 1.5667361 | IFIT1;HOPX |
| 856 | tissue homeostasis (GO:0001894) | 2/129 | 0.3704685 | 1.0000000 | 0 | 0 | 1.5503876 | 1.5395146 | SFTPD;KCNJ1 |
| 857 | negative regulation of developmental growth (GO:0048640) | 1/46 | 0.3705054 | 1.0000000 | 0 | 0 | 2.1739130 | 2.1584503 | GJA1 |
| 858 | positive regulation of tyrosine phosphorylation of STAT protein (GO:0042531) | 1/46 | 0.3705054 | 1.0000000 | 0 | 0 | 2.1739130 | 2.1584503 | CCL5 |
| 859 | inner ear development (GO:0048839) | 1/46 | 0.3705054 | 1.0000000 | 0 | 0 | 2.1739130 | 2.1584503 | LGR5 |
| 860 | leukocyte cell-cell adhesion (GO:0007159) | 1/46 | 0.3705054 | 1.0000000 | 0 | 0 | 2.1739130 | 2.1584503 | CCL5 |
| 861 | respiratory gaseous exchange (GO:0007585) | 1/46 | 0.3705054 | 1.0000000 | 0 | 0 | 2.1739130 | 2.1584503 | SFTPD |
| 862 | regulation of binding (GO:0051098) | 3/218 | 0.3724090 | 1.0000000 | 0 | 0 | 1.3761468 | 1.3593063 | IFIT1;HOPX;RUNX1T1 |
| 863 | positive regulation of protein catabolic process (GO:0045732) | 2/130 | 0.3740455 | 1.0000000 | 0 | 0 | 1.5384615 | 1.5128889 | GJA1;GPC3 |
| 864 | response to glucocorticoid (GO:0051384) | 2/130 | 0.3740455 | 1.0000000 | 0 | 0 | 1.5384615 | 1.5128889 | SCGB1A1;ABCG2 |
| 865 | positive regulation of homeostatic process (GO:0032846) | 2/130 | 0.3740455 | 1.0000000 | 0 | 0 | 1.5384615 | 1.5128889 | MC4R;PLA2G1B |
| 866 | circulatory system process (GO:0003013) | 2/130 | 0.3740455 | 1.0000000 | 0 | 0 | 1.5384615 | 1.5128889 | NPPC;RAMP2 |
| 867 | fatty acid beta-oxidation (GO:0006635) | 1/47 | 0.3768149 | 1.0000000 | 0 | 0 | 2.1276596 | 2.0765984 | ACOXL |
| 868 | regulation of synaptic transmission, glutamatergic (GO:0051966) | 1/47 | 0.3768149 | 1.0000000 | 0 | 0 | 2.1276596 | 2.0765984 | GRIK1 |
| 869 | neural precursor cell proliferation (GO:0061351) | 1/47 | 0.3768149 | 1.0000000 | 0 | 0 | 2.1276596 | 2.0765984 | HHIP |
| 870 | negative regulation of synaptic transmission (GO:0050805) | 1/47 | 0.3768149 | 1.0000000 | 0 | 0 | 2.1276596 | 2.0765984 | GRIK1 |
| 871 | acid secretion (GO:0046717) | 1/47 | 0.3768149 | 1.0000000 | 0 | 0 | 2.1276596 | 2.0765984 | PLA2G1B |
| 872 | skeletal muscle cell differentiation (GO:0035914) | 1/47 | 0.3768149 | 1.0000000 | 0 | 0 | 2.1276596 | 2.0765984 | HLF |
| 873 | cellular response to UV (GO:0034644) | 1/47 | 0.3768149 | 1.0000000 | 0 | 0 | 2.1276596 | 2.0765984 | MFAP4 |
| 874 | negative regulation of growth (GO:0045926) | 3/221 | 0.3805444 | 1.0000000 | 0 | 0 | 1.3574661 | 1.3115190 | GJA1;GPC3;SCGB3A1 |
| 875 | purine nucleotide biosynthetic process (GO:0006164) | 2/132 | 0.3811749 | 1.0000000 | 0 | 0 | 1.5151515 | 1.4613592 | NPPC;RAMP2 |
| 876 | cellular response to biotic stimulus (GO:0071216) | 2/132 | 0.3811749 | 1.0000000 | 0 | 0 | 1.5151515 | 1.4613592 | CX3CR1;CCL5 |
| 877 | positive regulation of alpha-beta T cell activation (GO:0046635) | 1/48 | 0.3830614 | 1.0000000 | 0 | 0 | 2.0833333 | 1.9990833 | HLA-DQB2 |
| 878 | natural killer cell activation (GO:0030101) | 1/48 | 0.3830614 | 1.0000000 | 0 | 0 | 2.0833333 | 1.9990833 | KLRK1 |
| 879 | intrinsic apoptotic signaling pathway by p53 class mediator (GO:0072332) | 1/48 | 0.3830614 | 1.0000000 | 0 | 0 | 2.0833333 | 1.9990833 | ZNF385B |
| 880 | regulation of mRNA stability (GO:0043488) | 1/48 | 0.3830614 | 1.0000000 | 0 | 0 | 2.0833333 | 1.9990833 | SCGB1A1 |
| 881 | regulation of homeostatic process (GO:0032844) | 4/314 | 0.3844827 | 1.0000000 | 0 | 0 | 1.2738854 | 1.2176516 | MC4R;GJA1;PLA2G1B;ALOX12 |
| 882 | regulation of blood pressure (GO:0008217) | 2/133 | 0.3847268 | 1.0000000 | 0 | 0 | 1.5037594 | 1.4364239 | RAMP2;OR51E2 |
| 883 | positive regulation of immune effector process (GO:0002699) | 2/133 | 0.3847268 | 1.0000000 | 0 | 0 | 1.5037594 | 1.4364239 | KLRK1;CRTAM |
| 884 | cellular response to lipid (GO:0071396) | 4/315 | 0.3867452 | 1.0000000 | 0 | 0 | 1.2698413 | 1.2063355 | CX3CR1;CCL5;OR51E2;ALOX12 |
| 885 | amine metabolic process (GO:0009308) | 2/134 | 0.3882699 | 1.0000000 | 0 | 0 | 1.4925373 | 1.4120217 | DDC;PLA2G1B |
| 886 | lipid modification (GO:0030258) | 2/134 | 0.3882699 | 1.0000000 | 0 | 0 | 1.4925373 | 1.4120217 | ACOXL;ALOX12 |
| 887 | cellular response to drug (GO:0035690) | 1/49 | 0.3892456 | 1.0000000 | 0 | 0 | 2.0408163 | 1.9256015 | DDC |
| 888 | positive regulation of fibroblast proliferation (GO:0048146) | 1/49 | 0.3892456 | 1.0000000 | 0 | 0 | 2.0408163 | 1.9256015 | PLA2G1B |
| 889 | response to dsRNA (GO:0043331) | 1/49 | 0.3892456 | 1.0000000 | 0 | 0 | 2.0408163 | 1.9256015 | IFIT1 |
| 890 | synapse assembly (GO:0007416) | 1/49 | 0.3892456 | 1.0000000 | 0 | 0 | 2.0408163 | 1.9256015 | GPM6A |
| 891 | developmental cell growth (GO:0048588) | 1/49 | 0.3892456 | 1.0000000 | 0 | 0 | 2.0408163 | 1.9256015 | DCX |
| 892 | regulation of lymphocyte apoptotic process (GO:0070228) | 1/49 | 0.3892456 | 1.0000000 | 0 | 0 | 2.0408163 | 1.9256015 | CCL5 |
| 893 | antigen processing and presentation (GO:0019882) | 3/225 | 0.3913564 | 1.0000000 | 0 | 0 | 1.3333333 | 1.2508489 | CD207;HLA-DOA;HLA-DQB2 |
| 894 | inositol lipid-mediated signaling (GO:0048017) | 2/136 | 0.3953292 | 1.0000000 | 0 | 0 | 1.4705882 | 1.3647595 | FGF9;FGF18 |
| 895 | phosphatidylinositol-mediated signaling (GO:0048015) | 2/136 | 0.3953292 | 1.0000000 | 0 | 0 | 1.4705882 | 1.3647595 | FGF9;FGF18 |
| 896 | cellular modified amino acid biosynthetic process (GO:0042398) | 1/50 | 0.3953682 | 1.0000000 | 0 | 0 | 2.0000000 | 1.8558758 | PADI3 |
| 897 | endothelial cell migration (GO:0043542) | 1/50 | 0.3953682 | 1.0000000 | 0 | 0 | 2.0000000 | 1.8558758 | GPR124 |
| 898 | regulation of cell junction assembly (GO:1901888) | 1/50 | 0.3953682 | 1.0000000 | 0 | 0 | 2.0000000 | 1.8558758 | GJA1 |
| 899 | negative regulation of protein binding (GO:0032091) | 1/50 | 0.3953682 | 1.0000000 | 0 | 0 | 2.0000000 | 1.8558758 | IFIT1 |
| 900 | cell projection morphogenesis (GO:0048858) | 3/228 | 0.3994350 | 1.0000000 | 0 | 0 | 1.3157895 | 1.2075055 | GPM6A;GJA1;DCX |
| 901 | positive regulation of proteolysis (GO:0045862) | 3/228 | 0.3994350 | 1.0000000 | 0 | 0 | 1.3157895 | 1.2075055 | PCOLCE2;DLC1;ALOX12 |
| 902 | response to lipopolysaccharide (GO:0032496) | 3/228 | 0.3994350 | 1.0000000 | 0 | 0 | 1.3157895 | 1.2075055 | CX3CR1;CCL5;SCGB1A1 |
| 903 | positive regulation of phosphatidylinositol 3-kinase signaling (GO:0014068) | 1/51 | 0.4014296 | 1.0000000 | 0 | 0 | 1.9607843 | 1.7896531 | CCL5 |
| 904 | regulation of potassium ion transport (GO:0043266) | 1/51 | 0.4014296 | 1.0000000 | 0 | 0 | 1.9607843 | 1.7896531 | KCNJ1 |
| 905 | regulation of glucose import (GO:0046324) | 1/51 | 0.4014296 | 1.0000000 | 0 | 0 | 1.9607843 | 1.7896531 | GPC3 |
| 906 | regulation of neurotransmitter secretion (GO:0046928) | 1/51 | 0.4014296 | 1.0000000 | 0 | 0 | 1.9607843 | 1.7896531 | SNCG |
| 907 | positive regulation of axonogenesis (GO:0050772) | 1/51 | 0.4014296 | 1.0000000 | 0 | 0 | 1.9607843 | 1.7896531 | ROBO2 |
| 908 | regulation of RNA stability (GO:0043487) | 1/51 | 0.4014296 | 1.0000000 | 0 | 0 | 1.9607843 | 1.7896531 | SCGB1A1 |
| 909 | negative regulation of response to wounding (GO:1903035) | 2/138 | 0.4023514 | 1.0000000 | 0 | 0 | 1.4492754 | 1.3194631 | PROS1;ALOX12 |
| 910 | response to light stimulus (GO:0009416) | 4/322 | 0.4025512 | 1.0000000 | 0 | 0 | 1.2422360 | 1.1303516 | MFAP4;OPN1SW;GPC3;CNGA1 |
| 911 | endocytosis (GO:0006897) | 4/323 | 0.4048039 | 1.0000000 | 0 | 0 | 1.2383901 | 1.1199413 | RAMP2;SFTPD;CLEC4F;LRP1B |
| 912 | regulation of hormone secretion (GO:0046883) | 3/230 | 0.4048048 | 1.0000000 | 0 | 0 | 1.3043478 | 1.1795874 | KISS1;CCL5;SCG5 |
| 913 | negative regulation of peptidase activity (GO:0010466) | 3/230 | 0.4048048 | 1.0000000 | 0 | 0 | 1.3043478 | 1.1795874 | PROS1;GPC3;A2ML1 |
| 914 | protein homooligomerization (GO:0051260) | 3/230 | 0.4048048 | 1.0000000 | 0 | 0 | 1.3043478 | 1.1795874 | SCUBE1;KCNA3;KCNA4 |
| 915 | immune response-activating cell surface receptor signaling pathway (GO:0002429) | 4/324 | 0.4070550 | 1.0000000 | 0 | 0 | 1.2345679 | 1.1096382 | IGHG4;TRAC;SKAP1;HLA-DQB2 |
| 916 | positive regulation of epithelial cell differentiation (GO:0030858) | 1/52 | 0.4074306 | 1.0000000 | 0 | 0 | 1.9230769 | 1.7267012 | ALOX12 |
| 917 | defense response to Gram-positive bacterium (GO:0050830) | 1/52 | 0.4074306 | 1.0000000 | 0 | 0 | 1.9230769 | 1.7267012 | PLA2G1B |
| 918 | demethylation (GO:0070988) | 1/52 | 0.4074306 | 1.0000000 | 0 | 0 | 1.9230769 | 1.7267012 | APOBEC2 |
| 919 | regulation of pH (GO:0006885) | 1/52 | 0.4074306 | 1.0000000 | 0 | 0 | 1.9230769 | 1.7267012 | SLC4A10 |
| 920 | regulation of vasoconstriction (GO:0019229) | 1/52 | 0.4074306 | 1.0000000 | 0 | 0 | 1.9230769 | 1.7267012 | GJA1 |
| 921 | regulation of excitatory postsynaptic membrane potential (GO:0060079) | 1/52 | 0.4074306 | 1.0000000 | 0 | 0 | 1.9230769 | 1.7267012 | GRIK1 |
| 922 | regulation of phagocytosis (GO:0050764) | 1/52 | 0.4074306 | 1.0000000 | 0 | 0 | 1.9230769 | 1.7267012 | SFTPD |
| 923 | positive regulation of lipid biosynthetic process (GO:0046889) | 1/52 | 0.4074306 | 1.0000000 | 0 | 0 | 1.9230769 | 1.7267012 | FABP3 |
| 924 | regulation of interleukin-8 production (GO:0032677) | 1/52 | 0.4074306 | 1.0000000 | 0 | 0 | 1.9230769 | 1.7267012 | BPI |
| 925 | positive regulation of protein transport (GO:0051222) | 3/231 | 0.4074846 | 1.0000000 | 0 | 0 | 1.2987013 | 1.1659119 | PLA2G1B;CRTAM;OR51E2 |
| 926 | ribonucleotide biosynthetic process (GO:0009260) | 2/140 | 0.4093351 | 1.0000000 | 0 | 0 | 1.4285714 | 1.2760304 | NPPC;RAMP2 |
| 927 | response to corticosteroid (GO:0031960) | 2/140 | 0.4093351 | 1.0000000 | 0 | 0 | 1.4285714 | 1.2760304 | SCGB1A1;ABCG2 |
| 928 | multi-organism reproductive process (GO:0044703) | 2/140 | 0.4093351 | 1.0000000 | 0 | 0 | 1.4285714 | 1.2760304 | RAMP2;SCGB1A1 |
| 929 | cell-substrate adhesion (GO:0031589) | 2/140 | 0.4093351 | 1.0000000 | 0 | 0 | 1.4285714 | 1.2760304 | ECM2;PPFIA2 |
| 930 | adult behavior (GO:0030534) | 2/141 | 0.4128121 | 1.0000000 | 0 | 0 | 1.4184397 | 1.2549827 | SNCG;GRIK1 |
| 931 | branching morphogenesis of an epithelial tube (GO:0048754) | 2/141 | 0.4128121 | 1.0000000 | 0 | 0 | 1.4184397 | 1.2549827 | HHIP;GPC3 |
| 932 | forebrain development (GO:0030900) | 1/53 | 0.4133717 | 1.0000000 | 0 | 0 | 1.8867925 | 1.6668075 | DLC1 |
| 933 | regulation of tyrosine phosphorylation of STAT protein (GO:0042509) | 1/53 | 0.4133717 | 1.0000000 | 0 | 0 | 1.8867925 | 1.6668075 | CCL5 |
| 934 | pyridine nucleotide metabolic process (GO:0019362) | 1/53 | 0.4133717 | 1.0000000 | 0 | 0 | 1.8867925 | 1.6668075 | QPRT |
| 935 | regulation of protein tyrosine kinase activity (GO:0061097) | 1/53 | 0.4133717 | 1.0000000 | 0 | 0 | 1.8867925 | 1.6668075 | CCL5 |
| 936 | nicotinamide nucleotide metabolic process (GO:0046496) | 1/53 | 0.4133717 | 1.0000000 | 0 | 0 | 1.8867925 | 1.6668075 | QPRT |
| 937 | lymphocyte mediated immunity (GO:0002449) | 1/53 | 0.4133717 | 1.0000000 | 0 | 0 | 1.8867925 | 1.6668075 | CRTAM |
| 938 | divalent metal ion transport (GO:0070838) | 3/234 | 0.4155023 | 1.0000000 | 0 | 0 | 1.2820513 | 1.1259834 | GPM6A;RAMP2;CCL5 |
| 939 | homophilic cell adhesion via plasma membrane adhesion molecules (GO:0007156) | 2/142 | 0.4162790 | 1.0000000 | 0 | 0 | 1.4084507 | 1.2343655 | ROBO2;CDH7 |
| 940 | digestive tract development (GO:0048565) | 1/54 | 0.4192536 | 1.0000000 | 0 | 0 | 1.8518519 | 1.6097765 | FGF9 |
| 941 | negative regulation of nuclear division (GO:0051784) | 1/54 | 0.4192536 | 1.0000000 | 0 | 0 | 1.8518519 | 1.6097765 | DMRT1 |
| 942 | peptide hormone secretion (GO:0030072) | 1/54 | 0.4192536 | 1.0000000 | 0 | 0 | 1.8518519 | 1.6097765 | MC4R |
| 943 | keratinocyte differentiation (GO:0030216) | 1/54 | 0.4192536 | 1.0000000 | 0 | 0 | 1.8518519 | 1.6097765 | TGM3 |
| 944 | regulation of cartilage development (GO:0061035) | 1/54 | 0.4192536 | 1.0000000 | 0 | 0 | 1.8518519 | 1.6097765 | FGF18 |
| 945 | ribose phosphate biosynthetic process (GO:0046390) | 2/144 | 0.4231821 | 1.0000000 | 0 | 0 | 1.3888889 | 1.1943787 | NPPC;RAMP2 |
| 946 | positive regulation of epithelial cell proliferation (GO:0050679) | 2/144 | 0.4231821 | 1.0000000 | 0 | 0 | 1.3888889 | 1.1943787 | FGF9;FLT4 |
| 947 | positive regulation of nuclear division (GO:0051785) | 1/55 | 0.4250768 | 1.0000000 | 0 | 0 | 1.8181818 | 1.5554281 | DMRT1 |
| 948 | peptidyl-proline modification (GO:0018208) | 1/55 | 0.4250768 | 1.0000000 | 0 | 0 | 1.8181818 | 1.5554281 | P4HA3 |
| 949 | arachidonic acid metabolic process (GO:0019369) | 1/55 | 0.4250768 | 1.0000000 | 0 | 0 | 1.8181818 | 1.5554281 | ALOX12 |
| 950 | embryonic digit morphogenesis (GO:0042733) | 1/55 | 0.4250768 | 1.0000000 | 0 | 0 | 1.8181818 | 1.5554281 | GJA1 |
| 951 | mesenchyme development (GO:0060485) | 1/55 | 0.4250768 | 1.0000000 | 0 | 0 | 1.8181818 | 1.5554281 | FGF9 |
| 952 | heart looping (GO:0001947) | 1/55 | 0.4250768 | 1.0000000 | 0 | 0 | 1.8181818 | 1.5554281 | GJA1 |
| 953 | divalent inorganic cation transport (GO:0072511) | 3/238 | 0.4261388 | 1.0000000 | 0 | 0 | 1.2605042 | 1.0751978 | GPM6A;RAMP2;CCL5 |
| 954 | purine-containing compound biosynthetic process (GO:0072522) | 2/146 | 0.4300432 | 1.0000000 | 0 | 0 | 1.3698630 | 1.1559858 | NPPC;RAMP2 |
| 955 | regulation of stress fiber assembly (GO:0051492) | 1/56 | 0.4308418 | 1.0000000 | 0 | 0 | 1.7857143 | 1.5035968 | DLC1 |
| 956 | peptide secretion (GO:0002790) | 1/56 | 0.4308418 | 1.0000000 | 0 | 0 | 1.7857143 | 1.5035968 | MC4R |
| 957 | positive regulation of JAK-STAT cascade (GO:0046427) | 1/56 | 0.4308418 | 1.0000000 | 0 | 0 | 1.7857143 | 1.5035968 | CCL5 |
| 958 | positive regulation of leukocyte chemotaxis (GO:0002690) | 1/56 | 0.4308418 | 1.0000000 | 0 | 0 | 1.7857143 | 1.5035968 | CCL5 |
| 959 | DNA methylation or demethylation (GO:0044728) | 1/56 | 0.4308418 | 1.0000000 | 0 | 0 | 1.7857143 | 1.5035968 | APOBEC2 |
| 960 | positive regulation of protein processing (GO:0010954) | 3/240 | 0.4314322 | 1.0000000 | 0 | 0 | 1.2500000 | 1.0508061 | PCOLCE2;DLC1;ALOX12 |
| 961 | positive regulation of protein maturation (GO:1903319) | 3/240 | 0.4314322 | 1.0000000 | 0 | 0 | 1.2500000 | 1.0508061 | PCOLCE2;DLC1;ALOX12 |
| 962 | cellular response to acid chemical (GO:0071229) | 2/147 | 0.4334576 | 1.0000000 | 0 | 0 | 1.3605442 | 1.1373622 | OR51E2;SNCG |
| 963 | response to hypoxia (GO:0001666) | 3/241 | 0.4340724 | 1.0000000 | 0 | 0 | 1.2448133 | 1.0388512 | NPPC;RAMP2;KCNK3 |
| 964 | adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains (GO:0002460) | 1/57 | 0.4365494 | 1.0000000 | 0 | 0 | 1.7543860 | 1.4541294 | CRTAM |
| 965 | actomyosin structure organization (GO:0031032) | 1/57 | 0.4365494 | 1.0000000 | 0 | 0 | 1.7543860 | 1.4541294 | MYOZ1 |
| 966 | establishment of synaptic vesicle localization (GO:0097480) | 1/57 | 0.4365494 | 1.0000000 | 0 | 0 | 1.7543860 | 1.4541294 | DDC |
| 967 | synaptic vesicle transport (GO:0048489) | 1/57 | 0.4365494 | 1.0000000 | 0 | 0 | 1.7543860 | 1.4541294 | DDC |
| 968 | insulin receptor signaling pathway (GO:0008286) | 2/148 | 0.4368612 | 1.0000000 | 0 | 0 | 1.3513514 | 1.1191078 | FGF9;FGF18 |
| 969 | response to molecule of bacterial origin (GO:0002237) | 3/243 | 0.4393395 | 1.0000000 | 0 | 0 | 1.2345679 | 1.0154110 | CX3CR1;CCL5;SCGB1A1 |
| 970 | regulation of cell-substrate adhesion (GO:0010810) | 2/149 | 0.4402537 | 1.0000000 | 0 | 0 | 1.3422819 | 1.1012136 | SMOC2;ECM2 |
| 971 | regulation of postsynaptic membrane potential (GO:0060078) | 1/58 | 0.4422000 | 1.0000000 | 0 | 0 | 1.7241379 | 1.4068845 | GRIK1 |
| 972 | regulation of extrinsic apoptotic signaling pathway in absence of ligand (GO:2001239) | 1/58 | 0.4422000 | 1.0000000 | 0 | 0 | 1.7241379 | 1.4068845 | CX3CR1 |
| 973 | response to decreased oxygen levels (GO:0036293) | 3/245 | 0.4445880 | 1.0000000 | 0 | 0 | 1.2244898 | 0.9925803 | NPPC;RAMP2;KCNK3 |
| 974 | regulation of synaptic transmission (GO:0050804) | 3/245 | 0.4445880 | 1.0000000 | 0 | 0 | 1.2244898 | 0.9925803 | KISS1;SNCG;GRIK1 |
| 975 | cellular response to nitrogen compound (GO:1901699) | 5/438 | 0.4461310 | 1.0000000 | 0 | 0 | 1.1415525 | 0.9213957 | DDC;FGF9;PLA2G1B;FGF18;IFIT1 |
| 976 | positive regulation of osteoblast differentiation (GO:0045669) | 1/59 | 0.4477942 | 1.0000000 | 0 | 0 | 1.6949153 | 1.3617314 | NPPC |
| 977 | chondroitin sulfate metabolic process (GO:0030204) | 1/59 | 0.4477942 | 1.0000000 | 0 | 0 | 1.6949153 | 1.3617314 | GPC3 |
| 978 | steroid hormone mediated signaling pathway (GO:0043401) | 1/59 | 0.4477942 | 1.0000000 | 0 | 0 | 1.6949153 | 1.3617314 | OR51E2 |
| 979 | regulation of inflammatory response (GO:0050727) | 3/247 | 0.4498174 | 1.0000000 | 0 | 0 | 1.2145749 | 0.9703403 | PROS1;CCL5;SCGB1A1 |
| 980 | cell part morphogenesis (GO:0032990) | 3/248 | 0.4524247 | 1.0000000 | 0 | 0 | 1.2096774 | 0.9594361 | GPM6A;GJA1;DCX |
| 981 | glycosaminoglycan catabolic process (GO:0006027) | 1/60 | 0.4533326 | 1.0000000 | 0 | 0 | 1.6666667 | 1.3185487 | GPC3 |
| 982 | cellular defense response (GO:0006968) | 1/60 | 0.4533326 | 1.0000000 | 0 | 0 | 1.6666667 | 1.3185487 | CX3CR1 |
| 983 | positive regulation of DNA replication (GO:0045740) | 1/60 | 0.4533326 | 1.0000000 | 0 | 0 | 1.6666667 | 1.3185487 | PLA2G1B |
| 984 | inner ear morphogenesis (GO:0042472) | 1/60 | 0.4533326 | 1.0000000 | 0 | 0 | 1.6666667 | 1.3185487 | FGF9 |
| 985 | pyridine-containing compound metabolic process (GO:0072524) | 1/61 | 0.4588157 | 1.0000000 | 0 | 0 | 1.6393443 | 1.2772240 | QPRT |
| 986 | cholesterol homeostasis (GO:0042632) | 1/61 | 0.4588157 | 1.0000000 | 0 | 0 | 1.6393443 | 1.2772240 | FABP3 |
| 987 | double-strand break repair via homologous recombination (GO:0000724) | 1/61 | 0.4588157 | 1.0000000 | 0 | 0 | 1.6393443 | 1.2772240 | MEIOB |
| 988 | kidney epithelium development (GO:0072073) | 1/62 | 0.4642441 | 1.0000000 | 0 | 0 | 1.6129032 | 1.2376529 | ROBO2 |
| 989 | regulation of adenylate cyclase activity (GO:0045761) | 1/62 | 0.4642441 | 1.0000000 | 0 | 0 | 1.6129032 | 1.2376529 | GABBR2 |
| 990 | embryonic heart tube morphogenesis (GO:0003143) | 1/62 | 0.4642441 | 1.0000000 | 0 | 0 | 1.6129032 | 1.2376529 | GJA1 |
| 991 | regulation of cation channel activity (GO:2001257) | 1/62 | 0.4642441 | 1.0000000 | 0 | 0 | 1.6129032 | 1.2376529 | KCNJ1 |
| 992 | recombinational repair (GO:0000725) | 1/62 | 0.4642441 | 1.0000000 | 0 | 0 | 1.6129032 | 1.2376529 | MEIOB |
| 993 | negative regulation of G-protein coupled receptor protein signaling pathway (GO:0045744) | 1/62 | 0.4642441 | 1.0000000 | 0 | 0 | 1.6129032 | 1.2376529 | CCL5 |
| 994 | phosphatidylcholine metabolic process (GO:0046470) | 1/62 | 0.4642441 | 1.0000000 | 0 | 0 | 1.6129032 | 1.2376529 | PLA2G1B |
| 995 | regulation of actin filament bundle assembly (GO:0032231) | 1/62 | 0.4642441 | 1.0000000 | 0 | 0 | 1.6129032 | 1.2376529 | DLC1 |
| 996 | sterol homeostasis (GO:0055092) | 1/62 | 0.4642441 | 1.0000000 | 0 | 0 | 1.6129032 | 1.2376529 | FABP3 |
| 997 | stem cell differentiation (GO:0048863) | 1/62 | 0.4642441 | 1.0000000 | 0 | 0 | 1.6129032 | 1.2376529 | GPM6A |
| 998 | regulation of innate immune response (GO:0045088) | 3/254 | 0.4679607 | 1.0000000 | 0 | 0 | 1.1811024 | 0.8968947 | KLRK1;CCL5;CRTAM |
| 999 | regulation of alpha-beta T cell activation (GO:0046634) | 1/63 | 0.4696183 | 1.0000000 | 0 | 0 | 1.5873016 | 1.1997381 | HLA-DQB2 |
| 1000 | modification of morphology or physiology of other organism involved in symbiotic interaction (GO:0051817) | 1/63 | 0.4696183 | 1.0000000 | 0 | 0 | 1.5873016 | 1.1997381 | CCL5 |
| 1001 | positive regulation of endothelial cell proliferation (GO:0001938) | 1/63 | 0.4696183 | 1.0000000 | 0 | 0 | 1.5873016 | 1.1997381 | FLT4 |
| 1002 | regulation of blood vessel size (GO:0050880) | 1/63 | 0.4696183 | 1.0000000 | 0 | 0 | 1.5873016 | 1.1997381 | NPPC |
| 1003 | neural nucleus development (GO:0048857) | 1/63 | 0.4696183 | 1.0000000 | 0 | 0 | 1.5873016 | 1.1997381 | FGF9 |
| 1004 | regulation of neurotransmitter transport (GO:0051588) | 1/63 | 0.4696183 | 1.0000000 | 0 | 0 | 1.5873016 | 1.1997381 | SNCG |
| 1005 | energy reserve metabolic process (GO:0006112) | 2/158 | 0.4702715 | 1.0000000 | 0 | 0 | 1.2658228 | 0.9549937 | MC4R;LEPR |
| 1006 | epithelium development (GO:0060429) | 3/256 | 0.4730965 | 1.0000000 | 0 | 0 | 1.1718750 | 0.8770968 | ROBO2;GJA1;EMP1 |
| 1007 | regulation of endopeptidase activity (GO:0052548) | 4/354 | 0.4735741 | 1.0000000 | 0 | 0 | 1.1299435 | 0.8445728 | DLC1;PROS1;ALOX12;A2ML1 |
| 1008 | negative regulation of angiogenesis (GO:0016525) | 1/64 | 0.4749389 | 1.0000000 | 0 | 0 | 1.5625000 | 1.1633893 | CX3CR1 |
| 1009 | fatty acid catabolic process (GO:0009062) | 1/64 | 0.4749389 | 1.0000000 | 0 | 0 | 1.5625000 | 1.1633893 | ACOXL |
| 1010 | regulation of tube size (GO:0035150) | 1/64 | 0.4749389 | 1.0000000 | 0 | 0 | 1.5625000 | 1.1633893 | NPPC |
| 1011 | regulation of synapse organization (GO:0050807) | 1/64 | 0.4749389 | 1.0000000 | 0 | 0 | 1.5625000 | 1.1633893 | ROBO2 |
| 1012 | positive regulation of stem cell proliferation (GO:2000648) | 1/64 | 0.4749389 | 1.0000000 | 0 | 0 | 1.5625000 | 1.1633893 | FGF9 |
| 1013 | meiotic nuclear division (GO:0007126) | 1/64 | 0.4749389 | 1.0000000 | 0 | 0 | 1.5625000 | 1.1633893 | MEIOB |
| 1014 | multicellular organismal development (GO:0007275) | 5/453 | 0.4752146 | 1.0000000 | 0 | 0 | 1.1037528 | 0.8211796 | ST6GAL2;HLF;LEPR;EMP1;TBX4 |
| 1015 | epithelial cell migration (GO:0010631) | 1/65 | 0.4802063 | 1.0000000 | 0 | 0 | 1.5384615 | 1.1285222 | GPR124 |
| 1016 | negative regulation of phosphatase activity (GO:0010923) | 1/65 | 0.4802063 | 1.0000000 | 0 | 0 | 1.5384615 | 1.1285222 | SLC7A14 |
| 1017 | oxidoreduction coenzyme metabolic process (GO:0006733) | 1/65 | 0.4802063 | 1.0000000 | 0 | 0 | 1.5384615 | 1.1285222 | QPRT |
| 1018 | positive regulation of peptide hormone secretion (GO:0090277) | 1/65 | 0.4802063 | 1.0000000 | 0 | 0 | 1.5384615 | 1.1285222 | KISS1 |
| 1019 | response to oxygen levels (GO:0070482) | 3/259 | 0.4807580 | 1.0000000 | 0 | 0 | 1.1583012 | 0.8483297 | NPPC;RAMP2;KCNK3 |
| 1020 | tissue morphogenesis (GO:0048729) | 4/358 | 0.4822501 | 1.0000000 | 0 | 0 | 1.1173184 | 0.8148519 | GJA1;HHIP;GPC3;TBX4 |
| 1021 | morphogenesis of a branching epithelium (GO:0061138) | 2/162 | 0.4833031 | 1.0000000 | 0 | 0 | 1.2345679 | 0.8976684 | HHIP;GPC3 |
| 1022 | skeletal system development (GO:0001501) | 2/162 | 0.4833031 | 1.0000000 | 0 | 0 | 1.2345679 | 0.8976684 | FGF9;FBN1 |
| 1023 | regulation of acute inflammatory response (GO:0002673) | 1/66 | 0.4854212 | 1.0000000 | 0 | 0 | 1.5151515 | 1.0950581 | PROS1 |
| 1024 | negative regulation of cell division (GO:0051782) | 1/66 | 0.4854212 | 1.0000000 | 0 | 0 | 1.5151515 | 1.0950581 | DMRT1 |
| 1025 | regulation of translational initiation (GO:0006446) | 1/66 | 0.4854212 | 1.0000000 | 0 | 0 | 1.5151515 | 1.0950581 | CCL5 |
| 1026 | regulation of bone mineralization (GO:0030500) | 1/66 | 0.4854212 | 1.0000000 | 0 | 0 | 1.5151515 | 1.0950581 | GJA1 |
| 1027 | regulation of phosphatidylinositol 3-kinase signaling (GO:0014066) | 1/66 | 0.4854212 | 1.0000000 | 0 | 0 | 1.5151515 | 1.0950581 | CCL5 |
| 1028 | positive regulation of translation (GO:0045727) | 1/66 | 0.4854212 | 1.0000000 | 0 | 0 | 1.5151515 | 1.0950581 | CCL5 |
| 1029 | dorsal/ventral pattern formation (GO:0009953) | 1/66 | 0.4854212 | 1.0000000 | 0 | 0 | 1.5151515 | 1.0950581 | HHIP |
| 1030 | negative regulation of blood vessel morphogenesis (GO:2000181) | 1/66 | 0.4854212 | 1.0000000 | 0 | 0 | 1.5151515 | 1.0950581 | CX3CR1 |
| 1031 | multicellular organismal response to stress (GO:0033555) | 1/66 | 0.4854212 | 1.0000000 | 0 | 0 | 1.5151515 | 1.0950581 | GRIK1 |
| 1032 | response to ammonium ion (GO:0060359) | 1/66 | 0.4854212 | 1.0000000 | 0 | 0 | 1.5151515 | 1.0950581 | SNCG |
| 1033 | cellular response to peptide hormone stimulus (GO:0071375) | 3/261 | 0.4858368 | 1.0000000 | 0 | 0 | 1.1494253 | 0.8297501 | FGF9;PLA2G1B;FGF18 |
| 1034 | fibroblast growth factor receptor signaling pathway (GO:0008543) | 2/163 | 0.4865301 | 1.0000000 | 0 | 0 | 1.2269939 | 0.8839957 | FGF9;FGF18 |
| 1035 | developmental growth (GO:0048589) | 2/163 | 0.4865301 | 1.0000000 | 0 | 0 | 1.2269939 | 0.8839957 | GJA1;DCX |
| 1036 | tube development (GO:0035295) | 2/164 | 0.4897447 | 1.0000000 | 0 | 0 | 1.2195122 | 0.8705745 | ROBO2;FGF9 |
| 1037 | vasculogenesis (GO:0001570) | 1/67 | 0.4905840 | 1.0000000 | 0 | 0 | 1.4925373 | 1.0629235 | RAMP2 |
| 1038 | aminoglycan catabolic process (GO:0006026) | 1/67 | 0.4905840 | 1.0000000 | 0 | 0 | 1.4925373 | 1.0629235 | GPC3 |
| 1039 | protein secretion (GO:0009306) | 1/67 | 0.4905840 | 1.0000000 | 0 | 0 | 1.4925373 | 1.0629235 | SNCG |
| 1040 | cellular iron ion homeostasis (GO:0006879) | 1/67 | 0.4905840 | 1.0000000 | 0 | 0 | 1.4925373 | 1.0629235 | ABCG2 |
| 1041 | cellular response to mechanical stimulus (GO:0071260) | 1/67 | 0.4905840 | 1.0000000 | 0 | 0 | 1.4925373 | 1.0629235 | GJA1 |
| 1042 | positive regulation of peptide secretion (GO:0002793) | 1/67 | 0.4905840 | 1.0000000 | 0 | 0 | 1.4925373 | 1.0629235 | KISS1 |
| 1043 | regulation of endocytosis (GO:0030100) | 2/165 | 0.4929467 | 1.0000000 | 0 | 0 | 1.2121212 | 0.8573991 | SFTPD;GPC3 |
| 1044 | cytokine production (GO:0001816) | 1/68 | 0.4956953 | 1.0000000 | 0 | 0 | 1.4705882 | 1.0320498 | PLA2G1B |
| 1045 | regulation of leukocyte chemotaxis (GO:0002688) | 1/68 | 0.4956953 | 1.0000000 | 0 | 0 | 1.4705882 | 1.0320498 | CCL5 |
| 1046 | glucose transport (GO:0015758) | 1/68 | 0.4956953 | 1.0000000 | 0 | 0 | 1.4705882 | 1.0320498 | PLA2G1B |
| 1047 | regulation of DNA metabolic process (GO:0051052) | 3/265 | 0.4959228 | 1.0000000 | 0 | 0 | 1.1320755 | 0.7939642 | NPPC;APOBEC3H;PLA2G1B |
| 1048 | negative regulation of cell migration (GO:0030336) | 2/166 | 0.4961360 | 1.0000000 | 0 | 0 | 1.2048193 | 0.8444640 | CX3CR1;DLC1 |
| 1049 | regulation of membrane potential (GO:0042391) | 3/266 | 0.4984290 | 1.0000000 | 0 | 0 | 1.1278195 | 0.7852941 | GJA1;CNGA1;GRIK1 |
| 1050 | hexose transport (GO:0008645) | 1/69 | 0.5007555 | 1.0000000 | 0 | 0 | 1.4492754 | 1.0023729 | PLA2G1B |
| 1051 | molting cycle process (GO:0022404) | 1/69 | 0.5007555 | 1.0000000 | 0 | 0 | 1.4492754 | 1.0023729 | TGM3 |
| 1052 | positive regulation of cytokine secretion (GO:0050715) | 1/69 | 0.5007555 | 1.0000000 | 0 | 0 | 1.4492754 | 1.0023729 | CRTAM |
| 1053 | hair cycle process (GO:0022405) | 1/69 | 0.5007555 | 1.0000000 | 0 | 0 | 1.4492754 | 1.0023729 | TGM3 |
| 1054 | alpha-amino acid biosynthetic process (GO:1901607) | 1/69 | 0.5007555 | 1.0000000 | 0 | 0 | 1.4492754 | 1.0023729 | PADI3 |
| 1055 | action potential (GO:0001508) | 1/69 | 0.5007555 | 1.0000000 | 0 | 0 | 1.4492754 | 1.0023729 | GJA1 |
| 1056 | hormone secretion (GO:0046879) | 1/70 | 0.5057652 | 1.0000000 | 0 | 0 | 1.4285714 | 0.9738324 | MC4R |
| 1057 | negative regulation of dephosphorylation (GO:0035305) | 1/70 | 0.5057652 | 1.0000000 | 0 | 0 | 1.4285714 | 0.9738324 | SLC7A14 |
| 1058 | response to heat (GO:0009408) | 1/70 | 0.5057652 | 1.0000000 | 0 | 0 | 1.4285714 | 0.9738324 | STAC |
| 1059 | positive regulation of muscle cell differentiation (GO:0051149) | 1/70 | 0.5057652 | 1.0000000 | 0 | 0 | 1.4285714 | 0.9738324 | HOPX |
| 1060 | negative regulation of vasculature development (GO:1901343) | 1/70 | 0.5057652 | 1.0000000 | 0 | 0 | 1.4285714 | 0.9738324 | CX3CR1 |
| 1061 | response to steroid hormone (GO:0048545) | 4/369 | 0.5058127 | 1.0000000 | 0 | 0 | 1.0840108 | 0.7388497 | RAMP2;OR51E2;SCGB1A1;ABCG2 |
| 1062 | response to inorganic substance (GO:0010035) | 4/370 | 0.5079318 | 1.0000000 | 0 | 0 | 1.0810811 | 0.7323331 | SCGB1A1;SNCG;KCNK3;ABCG2 |
| 1063 | negative regulation of cell motility (GO:2000146) | 2/170 | 0.5087658 | 1.0000000 | 0 | 0 | 1.1764706 | 0.7950205 | CX3CR1;DLC1 |
| 1064 | MAPK cascade (GO:0000165) | 2/170 | 0.5087658 | 1.0000000 | 0 | 0 | 1.1764706 | 0.7950205 | DOK5;CCL5 |
| 1065 | morphogenesis of a branching structure (GO:0001763) | 2/170 | 0.5087658 | 1.0000000 | 0 | 0 | 1.1764706 | 0.7950205 | HHIP;GPC3 |
| 1066 | tissue remodeling (GO:0048771) | 1/71 | 0.5107249 | 1.0000000 | 0 | 0 | 1.4084507 | 0.9463720 | GJA1 |
| 1067 | response to interleukin-1 (GO:0070555) | 1/71 | 0.5107249 | 1.0000000 | 0 | 0 | 1.4084507 | 0.9463720 | CCL5 |
| 1068 | single-organism nuclear import (GO:1902593) | 1/71 | 0.5107249 | 1.0000000 | 0 | 0 | 1.4084507 | 0.9463720 | FGF9 |
| 1069 | regulation of leukocyte apoptotic process (GO:2000106) | 1/71 | 0.5107249 | 1.0000000 | 0 | 0 | 1.4084507 | 0.9463720 | CCL5 |
| 1070 | receptor metabolic process (GO:0043112) | 1/71 | 0.5107249 | 1.0000000 | 0 | 0 | 1.4084507 | 0.9463720 | RAMP2 |
| 1071 | monosaccharide transport (GO:0015749) | 1/71 | 0.5107249 | 1.0000000 | 0 | 0 | 1.4084507 | 0.9463720 | PLA2G1B |
| 1072 | organophosphate ester transport (GO:0015748) | 1/71 | 0.5107249 | 1.0000000 | 0 | 0 | 1.4084507 | 0.9463720 | GJA1 |
| 1073 | positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains (GO:0002824) | 1/71 | 0.5107249 | 1.0000000 | 0 | 0 | 1.4084507 | 0.9463720 | HLA-DQB2 |
| 1074 | protein import into nucleus (GO:0006606) | 1/71 | 0.5107249 | 1.0000000 | 0 | 0 | 1.4084507 | 0.9463720 | FGF9 |
| 1075 | biomineral tissue development (GO:0031214) | 1/71 | 0.5107249 | 1.0000000 | 0 | 0 | 1.4084507 | 0.9463720 | GPC3 |
| 1076 | monocarboxylic acid metabolic process (GO:0032787) | 5/473 | 0.5131956 | 1.0000000 | 0 | 0 | 1.0570825 | 0.7051778 | CH25H;FABP3;ACOXL;PLA2G1B;ALOX12 |
| 1077 | smoothened signaling pathway (GO:0007224) | 1/72 | 0.5156351 | 1.0000000 | 0 | 0 | 1.3888889 | 0.9199388 | HHIP |
| 1078 | regulation of fatty acid metabolic process (GO:0019217) | 1/72 | 0.5156351 | 1.0000000 | 0 | 0 | 1.3888889 | 0.9199388 | FABP3 |
| 1079 | regulation of multicellular organism growth (GO:0040014) | 1/72 | 0.5156351 | 1.0000000 | 0 | 0 | 1.3888889 | 0.9199388 | NPPC |
| 1080 | regulation of calcium ion transport into cytosol (GO:0010522) | 1/72 | 0.5156351 | 1.0000000 | 0 | 0 | 1.3888889 | 0.9199388 | PLA2G1B |
| 1081 | negative regulation of purine nucleotide metabolic process (GO:1900543) | 1/72 | 0.5156351 | 1.0000000 | 0 | 0 | 1.3888889 | 0.9199388 | GABBR2 |
| 1082 | regulation of biomineral tissue development (GO:0070167) | 1/72 | 0.5156351 | 1.0000000 | 0 | 0 | 1.3888889 | 0.9199388 | GJA1 |
| 1083 | peptide transport (GO:0015833) | 1/72 | 0.5156351 | 1.0000000 | 0 | 0 | 1.3888889 | 0.9199388 | MC4R |
| 1084 | cellular response to peptide (GO:1901653) | 3/273 | 0.5157953 | 1.0000000 | 0 | 0 | 1.0989011 | 0.7275222 | FGF9;PLA2G1B;FGF18 |
| 1085 | regulation of ossification (GO:0030278) | 2/173 | 0.5181024 | 1.0000000 | 0 | 0 | 1.1560694 | 0.7602108 | NPPC;GJA1 |
| 1086 | positive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway (GO:0090100) | 1/73 | 0.5204962 | 1.0000000 | 0 | 0 | 1.3698630 | 0.8944830 | GPC3 |
| 1087 | regulation of cyclase activity (GO:0031279) | 1/73 | 0.5204962 | 1.0000000 | 0 | 0 | 1.3698630 | 0.8944830 | GABBR2 |
| 1088 | positive regulation of adaptive immune response (GO:0002821) | 1/74 | 0.5253088 | 1.0000000 | 0 | 0 | 1.3513514 | 0.8699580 | HLA-DQB2 |
| 1089 | nuclear import (GO:0051170) | 1/75 | 0.5300734 | 1.0000000 | 0 | 0 | 1.3333333 | 0.8463198 | FGF9 |
| 1090 | regulation of fibroblast proliferation (GO:0048145) | 1/75 | 0.5300734 | 1.0000000 | 0 | 0 | 1.3333333 | 0.8463198 | PLA2G1B |
| 1091 | muscle cell development (GO:0055001) | 1/75 | 0.5300734 | 1.0000000 | 0 | 0 | 1.3333333 | 0.8463198 | RAMP2 |
| 1092 | negative regulation of nucleotide metabolic process (GO:0045980) | 1/75 | 0.5300734 | 1.0000000 | 0 | 0 | 1.3333333 | 0.8463198 | GABBR2 |
| 1093 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (GO:0002479) | 1/75 | 0.5300734 | 1.0000000 | 0 | 0 | 1.3333333 | 0.8463198 | CD207 |
| 1094 | hormone transport (GO:0009914) | 1/75 | 0.5300734 | 1.0000000 | 0 | 0 | 1.3333333 | 0.8463198 | MC4R |
| 1095 | response to vitamin (GO:0033273) | 1/75 | 0.5300734 | 1.0000000 | 0 | 0 | 1.3333333 | 0.8463198 | ABCG2 |
| 1096 | regulation of cellular ketone metabolic process (GO:0010565) | 2/178 | 0.5334006 | 1.0000000 | 0 | 0 | 1.1235955 | 0.7061602 | FABP3;LEPR |
| 1097 | regulation of JAK-STAT cascade (GO:0046425) | 1/76 | 0.5347903 | 1.0000000 | 0 | 0 | 1.3157895 | 0.8235271 | CCL5 |
| 1098 | neural tube closure (GO:0001843) | 1/76 | 0.5347903 | 1.0000000 | 0 | 0 | 1.3157895 | 0.8235271 | DLC1 |
| 1099 | modification of morphology or physiology of other organism (GO:0035821) | 1/76 | 0.5347903 | 1.0000000 | 0 | 0 | 1.3157895 | 0.8235271 | CCL5 |
| 1100 | epidermal cell differentiation (GO:0009913) | 1/76 | 0.5347903 | 1.0000000 | 0 | 0 | 1.3157895 | 0.8235271 | TGM3 |
| 1101 | regulation of viral transcription (GO:0046782) | 1/76 | 0.5347903 | 1.0000000 | 0 | 0 | 1.3157895 | 0.8235271 | CCL5 |
| 1102 | tube closure (GO:0060606) | 1/77 | 0.5394601 | 1.0000000 | 0 | 0 | 1.2987013 | 0.8015408 | DLC1 |
| 1103 | regulation of lyase activity (GO:0051339) | 1/77 | 0.5394601 | 1.0000000 | 0 | 0 | 1.2987013 | 0.8015408 | GABBR2 |
| 1104 | regulation of DNA binding (GO:0051101) | 1/77 | 0.5394601 | 1.0000000 | 0 | 0 | 1.2987013 | 0.8015408 | RUNX1T1 |
| 1105 | protein localization to plasma membrane (GO:0072659) | 1/77 | 0.5394601 | 1.0000000 | 0 | 0 | 1.2987013 | 0.8015408 | RAMP2 |
| 1106 | axis specification (GO:0009798) | 1/78 | 0.5440833 | 1.0000000 | 0 | 0 | 1.2820513 | 0.7803242 | GPC3 |
| 1107 | positive regulation of leukocyte migration (GO:0002687) | 1/78 | 0.5440833 | 1.0000000 | 0 | 0 | 1.2820513 | 0.7803242 | CCL5 |
| 1108 | regulation of tumor necrosis factor production (GO:0032680) | 1/78 | 0.5440833 | 1.0000000 | 0 | 0 | 1.2820513 | 0.7803242 | BPI |
| 1109 | negative regulation of cellular component movement (GO:0051271) | 2/183 | 0.5483655 | 1.0000000 | 0 | 0 | 1.0928962 | 0.6566265 | CX3CR1;DLC1 |
| 1110 | locomotory behavior (GO:0007626) | 2/183 | 0.5483655 | 1.0000000 | 0 | 0 | 1.0928962 | 0.6566265 | SNCG;FEZF2 |
| 1111 | developmental growth involved in morphogenesis (GO:0060560) | 1/79 | 0.5486603 | 1.0000000 | 0 | 0 | 1.2658228 | 0.7598427 | DCX |
| 1112 | regulation of interferon-gamma production (GO:0032649) | 1/79 | 0.5486603 | 1.0000000 | 0 | 0 | 1.2658228 | 0.7598427 | SCGB1A1 |
| 1113 | antigen processing and presentation of exogenous peptide antigen via MHC class I (GO:0042590) | 1/79 | 0.5486603 | 1.0000000 | 0 | 0 | 1.2658228 | 0.7598427 | CD207 |
| 1114 | regulation of carbohydrate biosynthetic process (GO:0043255) | 1/79 | 0.5486603 | 1.0000000 | 0 | 0 | 1.2658228 | 0.7598427 | LEPR |
| 1115 | behavior (GO:0007610) | 5/494 | 0.5518315 | 1.0000000 | 0 | 0 | 1.0121457 | 0.6017334 | MC4R;GRID1;SNCG;GRIK1;FEZF2 |
| 1116 | regulation of tumor necrosis factor superfamily cytokine production (GO:1903555) | 1/80 | 0.5531916 | 1.0000000 | 0 | 0 | 1.2500000 | 0.7400636 | BPI |
| 1117 | multicellular organismal catabolic process (GO:0044243) | 1/80 | 0.5531916 | 1.0000000 | 0 | 0 | 1.2500000 | 0.7400636 | PLA2G1B |
| 1118 | regulation of cysteine-type endopeptidase activity involved in apoptotic process (GO:0043281) | 2/186 | 0.5571827 | 1.0000000 | 0 | 0 | 1.0752688 | 0.6288839 | DLC1;ALOX12 |
| 1119 | small molecule biosynthetic process (GO:0044283) | 4/394 | 0.5575014 | 1.0000000 | 0 | 0 | 1.0152284 | 0.5931881 | CH25H;PLA2G1B;PADI3;ALOX12 |
| 1120 | lymphocyte proliferation (GO:0046651) | 1/81 | 0.5576776 | 1.0000000 | 0 | 0 | 1.2345679 | 0.7209558 | CRTAM |
| 1121 | negative regulation of immune effector process (GO:0002698) | 1/81 | 0.5576776 | 1.0000000 | 0 | 0 | 1.2345679 | 0.7209558 | IFIT1 |
| 1122 | platelet degranulation (GO:0002576) | 1/81 | 0.5576776 | 1.0000000 | 0 | 0 | 1.2345679 | 0.7209558 | PROS1 |
| 1123 | phenol-containing compound metabolic process (GO:0018958) | 1/81 | 0.5576776 | 1.0000000 | 0 | 0 | 1.2345679 | 0.7209558 | DDC |
| 1124 | ethanolamine-containing compound metabolic process (GO:0042439) | 1/81 | 0.5576776 | 1.0000000 | 0 | 0 | 1.2345679 | 0.7209558 | PLA2G1B |
| 1125 | cellular response to organic cyclic compound (GO:0071407) | 3/291 | 0.5589306 | 1.0000000 | 0 | 0 | 1.0309278 | 0.5997217 | CCL5;OR51E2;IFIT1 |
| 1126 | monocarboxylic acid catabolic process (GO:0072329) | 1/82 | 0.5621188 | 1.0000000 | 0 | 0 | 1.2195122 | 0.7024903 | ACOXL |
| 1127 | male gonad development (GO:0008584) | 1/82 | 0.5621188 | 1.0000000 | 0 | 0 | 1.2195122 | 0.7024903 | FGF9 |
| 1128 | monovalent inorganic cation homeostasis (GO:0055067) | 1/82 | 0.5621188 | 1.0000000 | 0 | 0 | 1.2195122 | 0.7024903 | SLC4A10 |
| 1129 | regulation of peptide hormone secretion (GO:0090276) | 2/189 | 0.5658778 | 1.0000000 | 0 | 0 | 1.0582011 | 0.6025155 | KISS1;CCL5 |
| 1130 | negative regulation of protein kinase activity (GO:0006469) | 2/189 | 0.5658778 | 1.0000000 | 0 | 0 | 1.0582011 | 0.6025155 | CAMK2N1;DUSP26 |
| 1131 | positive regulation of T cell proliferation (GO:0042102) | 1/83 | 0.5665156 | 1.0000000 | 0 | 0 | 1.2048193 | 0.6846392 | CCL5 |
| 1132 | positive regulation of ossification (GO:0045778) | 1/83 | 0.5665156 | 1.0000000 | 0 | 0 | 1.2048193 | 0.6846392 | NPPC |
| 1133 | myeloid leukocyte differentiation (GO:0002573) | 1/83 | 0.5665156 | 1.0000000 | 0 | 0 | 1.2048193 | 0.6846392 | GPC3 |
| 1134 | activation of cysteine-type endopeptidase activity involved in apoptotic process (GO:0006919) | 1/83 | 0.5665156 | 1.0000000 | 0 | 0 | 1.2048193 | 0.6846392 | DLC1 |
| 1135 | amide transport (GO:0042886) | 1/83 | 0.5665156 | 1.0000000 | 0 | 0 | 1.2048193 | 0.6846392 | MC4R |
| 1136 | mononuclear cell proliferation (GO:0032943) | 1/83 | 0.5665156 | 1.0000000 | 0 | 0 | 1.2048193 | 0.6846392 | CRTAM |
| 1137 | cell-cell adhesion via plasma-membrane adhesion molecules (GO:0098742) | 2/190 | 0.5687489 | 1.0000000 | 0 | 0 | 1.0526316 | 0.5940172 | ROBO2;CDH7 |
| 1138 | regulation of interleukin-6 production (GO:0032675) | 1/84 | 0.5708685 | 1.0000000 | 0 | 0 | 1.1904762 | 0.6673766 | BPI |
| 1139 | cell-cell adhesion (GO:0098609) | 2/191 | 0.5716063 | 1.0000000 | 0 | 0 | 1.0471204 | 0.5856595 | ROBO2;CDH7 |
| 1140 | regulation of peptide secretion (GO:0002791) | 2/192 | 0.5744500 | 1.0000000 | 0 | 0 | 1.0416667 | 0.5774397 | KISS1;CCL5 |
| 1141 | regulation of striated muscle cell differentiation (GO:0051153) | 1/85 | 0.5751779 | 1.0000000 | 0 | 0 | 1.1764706 | 0.6506774 | HOPX |
| 1142 | regulation of anion transport (GO:0044070) | 1/85 | 0.5751779 | 1.0000000 | 0 | 0 | 1.1764706 | 0.6506774 | GRIK1 |
| 1143 | blood vessel development (GO:0001568) | 1/85 | 0.5751779 | 1.0000000 | 0 | 0 | 1.1764706 | 0.6506774 | GPC3 |
| 1144 | embryonic morphogenesis (GO:0048598) | 4/403 | 0.5753961 | 1.0000000 | 0 | 0 | 0.9925558 | 0.5485822 | GJA1;FGF9;GPC3;TBX4 |
| 1145 | lipid transport (GO:0006869) | 2/193 | 0.5772801 | 1.0000000 | 0 | 0 | 1.0362694 | 0.5693551 | FABP3;PLA2G1B |
| 1146 | epidermal growth factor receptor signaling pathway (GO:0007173) | 2/193 | 0.5772801 | 1.0000000 | 0 | 0 | 1.0362694 | 0.5693551 | FGF9;FGF18 |
| 1147 | long-chain fatty acid metabolic process (GO:0001676) | 1/86 | 0.5794443 | 1.0000000 | 0 | 0 | 1.1627907 | 0.6345183 | ALOX12 |
| 1148 | regulation of stem cell proliferation (GO:0072091) | 1/86 | 0.5794443 | 1.0000000 | 0 | 0 | 1.1627907 | 0.6345183 | FGF9 |
| 1149 | response to amino acid (GO:0043200) | 1/86 | 0.5794443 | 1.0000000 | 0 | 0 | 1.1627907 | 0.6345183 | ABCG2 |
| 1150 | visual perception (GO:0007601) | 2/195 | 0.5828991 | 1.0000000 | 0 | 0 | 1.0256410 | 0.5535806 | OPN1SW;CNGA1 |
| 1151 | positive regulation of cell projection organization (GO:0031346) | 2/195 | 0.5828991 | 1.0000000 | 0 | 0 | 1.0256410 | 0.5535806 | ROBO2;GPM6A |
| 1152 | feeding behavior (GO:0007631) | 1/87 | 0.5836680 | 1.0000000 | 0 | 0 | 1.1494253 | 0.6188770 | MC4R |
| 1153 | dicarboxylic acid metabolic process (GO:0043648) | 1/87 | 0.5836680 | 1.0000000 | 0 | 0 | 1.1494253 | 0.6188770 | QPRT |
| 1154 | negative regulation of proteolysis (GO:0045861) | 3/302 | 0.5841348 | 1.0000000 | 0 | 0 | 0.9933775 | 0.5340631 | PROS1;GPC3;A2ML1 |
| 1155 | ERBB signaling pathway (GO:0038127) | 2/196 | 0.5856881 | 1.0000000 | 0 | 0 | 1.0204082 | 0.5458856 | FGF9;FGF18 |
| 1156 | activation of cysteine-type endopeptidase activity (GO:0097202) | 1/88 | 0.5878495 | 1.0000000 | 0 | 0 | 1.1363636 | 0.6037322 | DLC1 |
| 1157 | regulation of endothelial cell proliferation (GO:0001936) | 1/88 | 0.5878495 | 1.0000000 | 0 | 0 | 1.1363636 | 0.6037322 | FLT4 |
| 1158 | adult locomotory behavior (GO:0008344) | 1/88 | 0.5878495 | 1.0000000 | 0 | 0 | 1.1363636 | 0.6037322 | SNCG |
| 1159 | regulation of cysteine-type endopeptidase activity (GO:2000116) | 2/197 | 0.5884633 | 1.0000000 | 0 | 0 | 1.0152284 | 0.5383154 | DLC1;ALOX12 |
| 1160 | positive regulation of MAP kinase activity (GO:0043406) | 2/197 | 0.5884633 | 1.0000000 | 0 | 0 | 1.0152284 | 0.5383154 | PLA2G1B;DIRAS2 |
| 1161 | lymphocyte activation (GO:0046649) | 3/304 | 0.5886188 | 1.0000000 | 0 | 0 | 0.9868421 | 0.5230032 | KLRK1;CD8B;CRTAM |
| 1162 | cellular response to organonitrogen compound (GO:0071417) | 4/411 | 0.5909584 | 1.0000000 | 0 | 0 | 0.9732360 | 0.5119315 | DDC;FGF9;PLA2G1B;FGF18 |
| 1163 | T cell activation (GO:0042110) | 2/198 | 0.5912248 | 1.0000000 | 0 | 0 | 1.0101010 | 0.5308676 | CD8B;CRTAM |
| 1164 | energy derivation by oxidation of organic compounds (GO:0015980) | 2/198 | 0.5912248 | 1.0000000 | 0 | 0 | 1.0101010 | 0.5308676 | MC4R;LEPR |
| 1165 | sensory perception of light stimulus (GO:0050953) | 2/198 | 0.5912248 | 1.0000000 | 0 | 0 | 1.0101010 | 0.5308676 | OPN1SW;CNGA1 |
| 1166 | RNA modification (GO:0009451) | 1/89 | 0.5919892 | 1.0000000 | 0 | 0 | 1.1235955 | 0.5890639 | APOBEC2 |
| 1167 | leukocyte proliferation (GO:0070661) | 1/89 | 0.5919892 | 1.0000000 | 0 | 0 | 1.1235955 | 0.5890639 | CRTAM |
| 1168 | cellular response to tumor necrosis factor (GO:0071356) | 1/89 | 0.5919892 | 1.0000000 | 0 | 0 | 1.1235955 | 0.5890639 | CCL5 |
| 1169 | cellular transition metal ion homeostasis (GO:0046916) | 1/89 | 0.5919892 | 1.0000000 | 0 | 0 | 1.1235955 | 0.5890639 | ABCG2 |
| 1170 | cellular modified amino acid metabolic process (GO:0006575) | 2/199 | 0.5939726 | 1.0000000 | 0 | 0 | 1.0050251 | 0.5235399 | PLA2G1B;PADI3 |
| 1171 | positive regulation of chemotaxis (GO:0050921) | 1/90 | 0.5960875 | 1.0000000 | 0 | 0 | 1.1111111 | 0.5748531 | CCL5 |
| 1172 | regulation of glucose transport (GO:0010827) | 1/90 | 0.5960875 | 1.0000000 | 0 | 0 | 1.1111111 | 0.5748531 | GPC3 |
| 1173 | water-soluble vitamin metabolic process (GO:0006767) | 1/90 | 0.5960875 | 1.0000000 | 0 | 0 | 1.1111111 | 0.5748531 | QPRT |
| 1174 | carboxylic acid catabolic process (GO:0046395) | 2/200 | 0.5967066 | 1.0000000 | 0 | 0 | 1.0000000 | 0.5163298 | ACOXL;QPRT |
| 1175 | organic acid catabolic process (GO:0016054) | 2/200 | 0.5967066 | 1.0000000 | 0 | 0 | 1.0000000 | 0.5163298 | ACOXL;QPRT |
| 1176 | protein processing (GO:0016485) | 2/201 | 0.5994269 | 1.0000000 | 0 | 0 | 0.9950249 | 0.5092351 | DLC1;SCG5 |
| 1177 | positive regulation of hormone secretion (GO:0046887) | 1/91 | 0.6001449 | 1.0000000 | 0 | 0 | 1.0989011 | 0.5610815 | KISS1 |
| 1178 | negative regulation of canonical Wnt signaling pathway (GO:0090090) | 1/91 | 0.6001449 | 1.0000000 | 0 | 0 | 1.0989011 | 0.5610815 | GPC3 |
| 1179 | adaptive immune response (GO:0002250) | 1/91 | 0.6001449 | 1.0000000 | 0 | 0 | 1.0989011 | 0.5610815 | CRTAM |
| 1180 | negative regulation of kinase activity (GO:0033673) | 2/202 | 0.6021334 | 1.0000000 | 0 | 0 | 0.9900990 | 0.5022537 | CAMK2N1;DUSP26 |
| 1181 | signal transduction by phosphorylation (GO:0023014) | 2/202 | 0.6021334 | 1.0000000 | 0 | 0 | 0.9900990 | 0.5022537 | DOK5;CCL5 |
| 1182 | iron ion homeostasis (GO:0055072) | 1/92 | 0.6041617 | 1.0000000 | 0 | 0 | 1.0869565 | 0.5477319 | ABCG2 |
| 1183 | interaction with host (GO:0051701) | 1/92 | 0.6041617 | 1.0000000 | 0 | 0 | 1.0869565 | 0.5477319 | IFIT1 |
| 1184 | aging (GO:0007568) | 2/204 | 0.6075053 | 1.0000000 | 0 | 0 | 0.9803922 | 0.4886220 | DDC;ALOX12 |
| 1185 | regulation of cytokine biosynthetic process (GO:0042035) | 1/93 | 0.6081384 | 1.0000000 | 0 | 0 | 1.0752688 | 0.5347880 | SFTPD |
| 1186 | hormone-mediated signaling pathway (GO:0009755) | 1/93 | 0.6081384 | 1.0000000 | 0 | 0 | 1.0752688 | 0.5347880 | OR51E2 |
| 1187 | meiotic cell cycle process (GO:1903046) | 1/93 | 0.6081384 | 1.0000000 | 0 | 0 | 1.0752688 | 0.5347880 | MEIOB |
| 1188 | regulation of glucose metabolic process (GO:0010906) | 1/94 | 0.6120753 | 1.0000000 | 0 | 0 | 1.0638298 | 0.5222340 | LEPR |
| 1189 | multicellular organismal metabolic process (GO:0044236) | 1/94 | 0.6120753 | 1.0000000 | 0 | 0 | 1.0638298 | 0.5222340 | PLA2G1B |
| 1190 | negative regulation of protein processing (GO:0010955) | 3/316 | 0.6148691 | 1.0000000 | 0 | 0 | 0.9493671 | 0.4617208 | PROS1;GPC3;A2ML1 |
| 1191 | negative regulation of protein maturation (GO:1903318) | 3/316 | 0.6148691 | 1.0000000 | 0 | 0 | 0.9493671 | 0.4617208 | PROS1;GPC3;A2ML1 |
| 1192 | regulation of cytokine-mediated signaling pathway (GO:0001959) | 1/95 | 0.6159728 | 1.0000000 | 0 | 0 | 1.0526316 | 0.5100552 | CCL5 |
| 1193 | negative regulation of binding (GO:0051100) | 1/95 | 0.6159728 | 1.0000000 | 0 | 0 | 1.0526316 | 0.5100552 | IFIT1 |
| 1194 | establishment of vesicle localization (GO:0051650) | 1/95 | 0.6159728 | 1.0000000 | 0 | 0 | 1.0526316 | 0.5100552 | DDC |
| 1195 | anatomical structure homeostasis (GO:0060249) | 2/208 | 0.6180843 | 1.0000000 | 0 | 0 | 0.9615385 | 0.4626254 | SFTPD;KCNJ1 |
| 1196 | lipid homeostasis (GO:0055088) | 1/96 | 0.6198314 | 1.0000000 | 0 | 0 | 1.0416667 | 0.4982372 | FABP3 |
| 1197 | fat cell differentiation (GO:0045444) | 1/96 | 0.6198314 | 1.0000000 | 0 | 0 | 1.0416667 | 0.4982372 | RUNX1T1 |
| 1198 | regulation of T cell differentiation (GO:0045580) | 1/97 | 0.6236514 | 1.0000000 | 0 | 0 | 1.0309278 | 0.4867667 | HLA-DOA |
| 1199 | regeneration (GO:0031099) | 1/97 | 0.6236514 | 1.0000000 | 0 | 0 | 1.0309278 | 0.4867667 | GJA1 |
| 1200 | negative regulation of extrinsic apoptotic signaling pathway (GO:2001237) | 1/97 | 0.6236514 | 1.0000000 | 0 | 0 | 1.0309278 | 0.4867667 | CX3CR1 |
| 1201 | nucleosome assembly (GO:0006334) | 1/97 | 0.6236514 | 1.0000000 | 0 | 0 | 1.0309278 | 0.4867667 | NAP1L3 |
| 1202 | coenzyme biosynthetic process (GO:0009108) | 1/98 | 0.6274332 | 1.0000000 | 0 | 0 | 1.0204082 | 0.4756306 | QPRT |
| 1203 | glycosaminoglycan biosynthetic process (GO:0006024) | 1/99 | 0.6311772 | 1.0000000 | 0 | 0 | 1.0101010 | 0.4648167 | GPC3 |
| 1204 | cellular response to hypoxia (GO:0071456) | 1/99 | 0.6311772 | 1.0000000 | 0 | 0 | 1.0101010 | 0.4648167 | KCNK3 |
| 1205 | cellular response to metal ion (GO:0071248) | 1/99 | 0.6311772 | 1.0000000 | 0 | 0 | 1.0101010 | 0.4648167 | KCNK3 |
| 1206 | positive regulation of sequence-specific DNA binding transcription factor activity (GO:0051091) | 2/214 | 0.6335421 | 1.0000000 | 0 | 0 | 0.9345794 | 0.4265691 | BEX1;PLA2G1B |
| 1207 | aminoglycan biosynthetic process (GO:0006023) | 1/100 | 0.6348838 | 1.0000000 | 0 | 0 | 1.0000000 | 0.4543133 | GPC3 |
| 1208 | response to estradiol (GO:0032355) | 1/100 | 0.6348838 | 1.0000000 | 0 | 0 | 1.0000000 | 0.4543133 | RAMP2 |
| 1209 | fertilization (GO:0009566) | 1/100 | 0.6348838 | 1.0000000 | 0 | 0 | 1.0000000 | 0.4543133 | MEIOB |
| 1210 | organophosphate biosynthetic process (GO:0090407) | 4/436 | 0.6373809 | 1.0000000 | 0 | 0 | 0.9174312 | 0.4131999 | NPPC;RAMP2;PLA2G1B;QPRT |
| 1211 | negative regulation of cytoskeleton organization (GO:0051494) | 1/101 | 0.6385533 | 1.0000000 | 0 | 0 | 0.9900990 | 0.4441090 | DLC1 |
| 1212 | regulation of response to cytokine stimulus (GO:0060759) | 1/101 | 0.6385533 | 1.0000000 | 0 | 0 | 0.9900990 | 0.4441090 | CCL5 |
| 1213 | protein import (GO:0017038) | 1/101 | 0.6385533 | 1.0000000 | 0 | 0 | 0.9900990 | 0.4441090 | FGF9 |
| 1214 | cellular response to decreased oxygen levels (GO:0036294) | 1/101 | 0.6385533 | 1.0000000 | 0 | 0 | 0.9900990 | 0.4441090 | KCNK3 |
| 1215 | protein localization to nucleus (GO:0034504) | 1/101 | 0.6385533 | 1.0000000 | 0 | 0 | 0.9900990 | 0.4441090 | FGF9 |
| 1216 | cellular component morphogenesis (GO:0032989) | 4/437 | 0.6391657 | 1.0000000 | 0 | 0 | 0.9153318 | 0.4096948 | GPM6A;GJA1;DMRT1;DCX |
| 1217 | positive regulation of neuron differentiation (GO:0045666) | 2/217 | 0.6410868 | 1.0000000 | 0 | 0 | 0.9216590 | 0.4097607 | ROBO2;FEZF2 |
| 1218 | organic hydroxy compound transport (GO:0015850) | 1/102 | 0.6421861 | 1.0000000 | 0 | 0 | 0.9803922 | 0.4341933 | SLC5A7 |
| 1219 | DNA catabolic process (GO:0006308) | 1/102 | 0.6421861 | 1.0000000 | 0 | 0 | 0.9803922 | 0.4341933 | MEIOB |
| 1220 | regulation of phosphatase activity (GO:0010921) | 1/102 | 0.6421861 | 1.0000000 | 0 | 0 | 0.9803922 | 0.4341933 | SLC7A14 |
| 1221 | carbohydrate transport (GO:0008643) | 1/102 | 0.6421861 | 1.0000000 | 0 | 0 | 0.9803922 | 0.4341933 | PLA2G1B |
| 1222 | zymogen activation (GO:0031638) | 1/102 | 0.6421861 | 1.0000000 | 0 | 0 | 0.9803922 | 0.4341933 | DLC1 |
| 1223 | peptidyl-tyrosine dephosphorylation (GO:0035335) | 1/102 | 0.6421861 | 1.0000000 | 0 | 0 | 0.9803922 | 0.4341933 | DUSP26 |
| 1224 | immune response-activating signal transduction (GO:0002757) | 4/440 | 0.6444860 | 1.0000000 | 0 | 0 | 0.9090909 | 0.3993656 | IGHG4;TRAC;SKAP1;HLA-DQB2 |
| 1225 | positive regulation of mitotic cell cycle (GO:0045931) | 1/103 | 0.6457826 | 1.0000000 | 0 | 0 | 0.9708738 | 0.4245557 | DMRT1 |
| 1226 | regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains (GO:0002822) | 1/103 | 0.6457826 | 1.0000000 | 0 | 0 | 0.9708738 | 0.4245557 | HLA-DQB2 |
| 1227 | positive regulation of lipid metabolic process (GO:0045834) | 1/103 | 0.6457826 | 1.0000000 | 0 | 0 | 0.9708738 | 0.4245557 | FABP3 |
| 1228 | response to radiation (GO:0009314) | 4/442 | 0.6480044 | 1.0000000 | 0 | 0 | 0.9049774 | 0.3926315 | MFAP4;OPN1SW;GPC3;CNGA1 |
| 1229 | antigen processing and presentation of peptide antigen via MHC class I (GO:0002474) | 1/104 | 0.6493431 | 1.0000000 | 0 | 0 | 0.9615385 | 0.4151866 | CD207 |
| 1230 | alcohol biosynthetic process (GO:0046165) | 1/104 | 0.6493431 | 1.0000000 | 0 | 0 | 0.9615385 | 0.4151866 | CH25H |
| 1231 | response to ketone (GO:1901654) | 1/105 | 0.6528680 | 1.0000000 | 0 | 0 | 0.9523810 | 0.4060766 | RAMP2 |
| 1232 | negative regulation of endopeptidase activity (GO:0010951) | 2/222 | 0.6533903 | 1.0000000 | 0 | 0 | 0.9009009 | 0.3834060 | PROS1;A2ML1 |
| 1233 | protein maturation (GO:0051604) | 2/222 | 0.6533903 | 1.0000000 | 0 | 0 | 0.9009009 | 0.3834060 | DLC1;SCG5 |
| 1234 | membrane depolarization (GO:0051899) | 1/106 | 0.6563576 | 1.0000000 | 0 | 0 | 0.9433962 | 0.3972165 | GRIK1 |
| 1235 | cellular amino acid biosynthetic process (GO:0008652) | 1/106 | 0.6563576 | 1.0000000 | 0 | 0 | 0.9433962 | 0.3972165 | PADI3 |
| 1236 | regulation of cytokine secretion (GO:0050707) | 1/106 | 0.6563576 | 1.0000000 | 0 | 0 | 0.9433962 | 0.3972165 | CRTAM |
| 1237 | regulation of osteoblast differentiation (GO:0045667) | 1/106 | 0.6563576 | 1.0000000 | 0 | 0 | 0.9433962 | 0.3972165 | NPPC |
| 1238 | hematopoietic progenitor cell differentiation (GO:0002244) | 1/106 | 0.6563576 | 1.0000000 | 0 | 0 | 0.9433962 | 0.3972165 | APOBEC3H |
| 1239 | epithelial cell development (GO:0002064) | 1/107 | 0.6598123 | 1.0000000 | 0 | 0 | 0.9345794 | 0.3885980 | DMRT1 |
| 1240 | positive regulation of JNK cascade (GO:0046330) | 1/107 | 0.6598123 | 1.0000000 | 0 | 0 | 0.9345794 | 0.3885980 | FLT4 |
| 1241 | positive regulation of cell growth (GO:0030307) | 1/107 | 0.6598123 | 1.0000000 | 0 | 0 | 0.9345794 | 0.3885980 | ALOX12 |
| 1242 | steroid biosynthetic process (GO:0006694) | 1/108 | 0.6632325 | 1.0000000 | 0 | 0 | 0.9259259 | 0.3802127 | CH25H |
| 1243 | maintenance of protein location (GO:0045185) | 1/108 | 0.6632325 | 1.0000000 | 0 | 0 | 0.9259259 | 0.3802127 | FBN1 |
| 1244 | regulation of epithelial cell differentiation (GO:0030856) | 1/109 | 0.6666184 | 1.0000000 | 0 | 0 | 0.9174312 | 0.3720527 | ALOX12 |
| 1245 | regulation of Ras protein signal transduction (GO:0046578) | 1/109 | 0.6666184 | 1.0000000 | 0 | 0 | 0.9174312 | 0.3720527 | DLC1 |
| 1246 | response to ethanol (GO:0045471) | 1/109 | 0.6666184 | 1.0000000 | 0 | 0 | 0.9174312 | 0.3720527 | NPPC |
| 1247 | cellular response to oxygen levels (GO:0071453) | 1/109 | 0.6666184 | 1.0000000 | 0 | 0 | 0.9174312 | 0.3720527 | KCNK3 |
| 1248 | axonogenesis (GO:0007409) | 1/109 | 0.6666184 | 1.0000000 | 0 | 0 | 0.9174312 | 0.3720527 | DCX |
| 1249 | cellular process involved in reproduction in multicellular organism (GO:0022412) | 2/228 | 0.6677106 | 1.0000000 | 0 | 0 | 0.8771930 | 0.3542987 | ROBO2;DMRT1 |
| 1250 | regulation of leukocyte migration (GO:0002685) | 1/110 | 0.6699705 | 1.0000000 | 0 | 0 | 0.9090909 | 0.3641106 | CCL5 |
| 1251 | cellular response to inorganic substance (GO:0071241) | 1/110 | 0.6699705 | 1.0000000 | 0 | 0 | 0.9090909 | 0.3641106 | KCNK3 |
| 1252 | regulation of hormone levels (GO:0010817) | 2/229 | 0.6700506 | 1.0000000 | 0 | 0 | 0.8733624 | 0.3496962 | MC4R;SCG5 |
| 1253 | response to tumor necrosis factor (GO:0034612) | 1/111 | 0.6732890 | 1.0000000 | 0 | 0 | 0.9009009 | 0.3563789 | CCL5 |
| 1254 | regulation of peptide transport (GO:0090087) | 2/231 | 0.6746907 | 1.0000000 | 0 | 0 | 0.8658009 | 0.3406934 | KISS1;CCL5 |
| 1255 | negative regulation of phosphorus metabolic process (GO:0010563) | 4/458 | 0.6753226 | 1.0000000 | 0 | 0 | 0.8733624 | 0.3428513 | GABBR2;CAMK2N1;SLC7A14;DUSP26 |
| 1256 | negative regulation of phosphate metabolic process (GO:0045936) | 4/458 | 0.6753226 | 1.0000000 | 0 | 0 | 0.8733624 | 0.3428513 | GABBR2;CAMK2N1;SLC7A14;DUSP26 |
| 1257 | regulation of mitosis (GO:0007088) | 1/112 | 0.6765743 | 1.0000000 | 0 | 0 | 0.8928571 | 0.3488508 | DMRT1 |
| 1258 | cell activation involved in immune response (GO:0002263) | 1/112 | 0.6765743 | 1.0000000 | 0 | 0 | 0.8928571 | 0.3488508 | CX3CR1 |
| 1259 | leukocyte activation involved in immune response (GO:0002366) | 1/112 | 0.6765743 | 1.0000000 | 0 | 0 | 0.8928571 | 0.3488508 | CX3CR1 |
| 1260 | regulation of adaptive immune response (GO:0002819) | 1/112 | 0.6765743 | 1.0000000 | 0 | 0 | 0.8928571 | 0.3488508 | HLA-DQB2 |
| 1261 | gonad development (GO:0008406) | 1/112 | 0.6765743 | 1.0000000 | 0 | 0 | 0.8928571 | 0.3488508 | FGF9 |
| 1262 | regulation of cell shape (GO:0008360) | 1/112 | 0.6765743 | 1.0000000 | 0 | 0 | 0.8928571 | 0.3488508 | DLC1 |
| 1263 | lipid catabolic process (GO:0016042) | 2/232 | 0.6769910 | 1.0000000 | 0 | 0 | 0.8620690 | 0.3362908 | ACOXL;PLA2G1B |
| 1264 | exocytosis (GO:0006887) | 2/233 | 0.6792781 | 1.0000000 | 0 | 0 | 0.8583691 | 0.3319525 | PROS1;CCL5 |
| 1265 | peptide metabolic process (GO:0006518) | 1/113 | 0.6798268 | 1.0000000 | 0 | 0 | 0.8849558 | 0.3415197 | SCG5 |
| 1266 | regulation of lipid biosynthetic process (GO:0046890) | 1/113 | 0.6798268 | 1.0000000 | 0 | 0 | 0.8849558 | 0.3415197 | FABP3 |
| 1267 | protein-DNA complex assembly (GO:0065004) | 1/113 | 0.6798268 | 1.0000000 | 0 | 0 | 0.8849558 | 0.3415197 | NAP1L3 |
| 1268 | regulation of cell division (GO:0051302) | 2/234 | 0.6815520 | 1.0000000 | 0 | 0 | 0.8547009 | 0.3276775 | DMRT1;FGF9 |
| 1269 | double-strand break repair (GO:0006302) | 1/114 | 0.6830467 | 1.0000000 | 0 | 0 | 0.8771930 | 0.3343790 | MEIOB |
| 1270 | tube formation (GO:0035148) | 1/114 | 0.6830467 | 1.0000000 | 0 | 0 | 0.8771930 | 0.3343790 | DLC1 |
| 1271 | regulation of axonogenesis (GO:0050770) | 1/114 | 0.6830467 | 1.0000000 | 0 | 0 | 0.8771930 | 0.3343790 | ROBO2 |
| 1272 | positive regulation of lymphocyte proliferation (GO:0050671) | 1/115 | 0.6862344 | 1.0000000 | 0 | 0 | 0.8695652 | 0.3274226 | CCL5 |
| 1273 | Fc receptor signaling pathway (GO:0038093) | 3/352 | 0.6867026 | 1.0000000 | 0 | 0 | 0.8522727 | 0.3203301 | IGHG4;FGF9;FGF18 |
| 1274 | negative regulation of organelle organization (GO:0010639) | 2/237 | 0.6882952 | 1.0000000 | 0 | 0 | 0.8438819 | 0.3152215 | DMRT1;DLC1 |
| 1275 | extracellular matrix disassembly (GO:0022617) | 1/116 | 0.6893902 | 1.0000000 | 0 | 0 | 0.8620690 | 0.3206447 | FBN1 |
| 1276 | positive regulation of mononuclear cell proliferation (GO:0032946) | 1/116 | 0.6893902 | 1.0000000 | 0 | 0 | 0.8620690 | 0.3206447 | CCL5 |
| 1277 | response to UV (GO:0009411) | 1/117 | 0.6925144 | 1.0000000 | 0 | 0 | 0.8547009 | 0.3140395 | MFAP4 |
| 1278 | steroid metabolic process (GO:0008202) | 2/240 | 0.6949213 | 1.0000000 | 0 | 0 | 0.8333333 | 0.3032972 | CH25H;LEPR |
| 1279 | positive regulation of stress-activated MAPK cascade (GO:0032874) | 1/118 | 0.6956073 | 1.0000000 | 0 | 0 | 0.8474576 | 0.3076017 | FLT4 |
| 1280 | regulation of DNA replication (GO:0006275) | 1/118 | 0.6956073 | 1.0000000 | 0 | 0 | 0.8474576 | 0.3076017 | PLA2G1B |
| 1281 | cell maturation (GO:0048469) | 1/118 | 0.6956073 | 1.0000000 | 0 | 0 | 0.8474576 | 0.3076017 | GJA1 |
| 1282 | embryonic organ development (GO:0048568) | 1/119 | 0.6986693 | 1.0000000 | 0 | 0 | 0.8403361 | 0.3013258 | FGF9 |
| 1283 | positive regulation of leukocyte proliferation (GO:0070665) | 1/119 | 0.6986693 | 1.0000000 | 0 | 0 | 0.8403361 | 0.3013258 | CCL5 |
| 1284 | positive regulation of stress-activated protein kinase signaling cascade (GO:0070304) | 1/119 | 0.6986693 | 1.0000000 | 0 | 0 | 0.8403361 | 0.3013258 | FLT4 |
| 1285 | epidermis development (GO:0008544) | 1/120 | 0.7017006 | 1.0000000 | 0 | 0 | 0.8333333 | 0.2952070 | EMP1 |
| 1286 | nucleosome organization (GO:0034728) | 1/120 | 0.7017006 | 1.0000000 | 0 | 0 | 0.8333333 | 0.2952070 | NAP1L3 |
| 1287 | regulation of cell projection assembly (GO:0060491) | 1/120 | 0.7017006 | 1.0000000 | 0 | 0 | 0.8333333 | 0.2952070 | GPM6A |
| 1288 | transition metal ion homeostasis (GO:0055076) | 1/120 | 0.7017006 | 1.0000000 | 0 | 0 | 0.8333333 | 0.2952070 | ABCG2 |
| 1289 | negative regulation of defense response (GO:0031348) | 1/120 | 0.7017006 | 1.0000000 | 0 | 0 | 0.8333333 | 0.2952070 | IFIT1 |
| 1290 | plasma membrane organization (GO:0007009) | 1/121 | 0.7047016 | 1.0000000 | 0 | 0 | 0.8264463 | 0.2892403 | RAMP2 |
| 1291 | neuron development (GO:0048666) | 1/121 | 0.7047016 | 1.0000000 | 0 | 0 | 0.8264463 | 0.2892403 | ROBO2 |
| 1292 | germ cell development (GO:0007281) | 1/121 | 0.7047016 | 1.0000000 | 0 | 0 | 0.8264463 | 0.2892403 | DMRT1 |
| 1293 | response to temperature stimulus (GO:0009266) | 1/122 | 0.7076726 | 1.0000000 | 0 | 0 | 0.8196721 | 0.2834211 | STAC |
| 1294 | adenylate cyclase-modulating G-protein coupled receptor signaling pathway (GO:0007188) | 1/122 | 0.7076726 | 1.0000000 | 0 | 0 | 0.8196721 | 0.2834211 | MC4R |
| 1295 | regulation of gene expression, epigenetic (GO:0040029) | 1/122 | 0.7076726 | 1.0000000 | 0 | 0 | 0.8196721 | 0.2834211 | APOBEC2 |
| 1296 | vitamin metabolic process (GO:0006766) | 1/122 | 0.7076726 | 1.0000000 | 0 | 0 | 0.8196721 | 0.2834211 | QPRT |
| 1297 | regulation of muscle cell differentiation (GO:0051147) | 1/122 | 0.7076726 | 1.0000000 | 0 | 0 | 0.8196721 | 0.2834211 | HOPX |
| 1298 | regionalization (GO:0003002) | 2/247 | 0.7099322 | 1.0000000 | 0 | 0 | 0.8097166 | 0.2773974 | HHIP;FEZF2 |
| 1299 | cellular response to steroid hormone stimulus (GO:0071383) | 1/123 | 0.7106138 | 1.0000000 | 0 | 0 | 0.8130081 | 0.2777449 | OR51E2 |
| 1300 | ameboidal-type cell migration (GO:0001667) | 1/123 | 0.7106138 | 1.0000000 | 0 | 0 | 0.8130081 | 0.2777449 | GPR124 |
| 1301 | positive regulation of cell morphogenesis involved in differentiation (GO:0010770) | 1/123 | 0.7106138 | 1.0000000 | 0 | 0 | 0.8130081 | 0.2777449 | ROBO2 |
| 1302 | regulation of lymphocyte differentiation (GO:0045619) | 1/124 | 0.7135255 | 1.0000000 | 0 | 0 | 0.8064516 | 0.2722073 | HLA-DOA |
| 1303 | mucopolysaccharide metabolic process (GO:1903510) | 1/124 | 0.7135255 | 1.0000000 | 0 | 0 | 0.8064516 | 0.2722073 | GPC3 |
| 1304 | positive regulation of DNA metabolic process (GO:0051054) | 1/124 | 0.7135255 | 1.0000000 | 0 | 0 | 0.8064516 | 0.2722073 | PLA2G1B |
| 1305 | neuron projection guidance (GO:0097485) | 3/367 | 0.7135377 | 1.0000000 | 0 | 0 | 0.8174387 | 0.2759019 | ROBO2;DCX;FEZF2 |
| 1306 | axon guidance (GO:0007411) | 3/367 | 0.7135377 | 1.0000000 | 0 | 0 | 0.8174387 | 0.2759019 | ROBO2;DCX;FEZF2 |
| 1307 | phosphatidylinositol metabolic process (GO:0046488) | 1/125 | 0.7164081 | 1.0000000 | 0 | 0 | 0.8000000 | 0.2668042 | PLA2G1B |
| 1308 | positive regulation of NF-kappaB transcription factor activity (GO:0051092) | 1/126 | 0.7192619 | 1.0000000 | 0 | 0 | 0.7936508 | 0.2615316 | PLA2G1B |
| 1309 | activation of immune response (GO:0002253) | 4/487 | 0.7210317 | 1.0000000 | 0 | 0 | 0.8213552 | 0.2686424 | IGHG4;TRAC;SKAP1;HLA-DQB2 |
| 1310 | circadian rhythm (GO:0007623) | 1/127 | 0.7220870 | 1.0000000 | 0 | 0 | 0.7874016 | 0.2563855 | DDC |
| 1311 | cofactor biosynthetic process (GO:0051188) | 1/127 | 0.7220870 | 1.0000000 | 0 | 0 | 0.7874016 | 0.2563855 | QPRT |
| 1312 | actin cytoskeleton organization (GO:0030036) | 2/253 | 0.7223054 | 1.0000000 | 0 | 0 | 0.7905138 | 0.2571598 | DLC1;MYOZ1 |
| 1313 | calcium ion transmembrane transport (GO:0070588) | 1/128 | 0.7248839 | 1.0000000 | 0 | 0 | 0.7812500 | 0.2513623 | GPM6A |
| 1314 | response to metal ion (GO:0010038) | 2/255 | 0.7263303 | 1.0000000 | 0 | 0 | 0.7843137 | 0.2507846 | KCNK3;ABCG2 |
| 1315 | generation of precursor metabolites and energy (GO:0006091) | 3/375 | 0.7271132 | 1.0000000 | 0 | 0 | 0.8000000 | 0.2549385 | MC4R;LEPR;RUNX1T1 |
| 1316 | inflammatory response (GO:0006954) | 3/376 | 0.7287745 | 1.0000000 | 0 | 0 | 0.7978723 | 0.2524396 | GJA1;SCUBE1;CCL5 |
| 1317 | positive regulation of protein serine/threonine kinase activity (GO:0071902) | 2/257 | 0.7303060 | 1.0000000 | 0 | 0 | 0.7782101 | 0.2445850 | PLA2G1B;DIRAS2 |
| 1318 | positive regulation of response to wounding (GO:1903036) | 1/130 | 0.7303939 | 1.0000000 | 0 | 0 | 0.7692308 | 0.2416702 | HOPX |
| 1319 | negative regulation of MAPK cascade (GO:0043409) | 1/130 | 0.7303939 | 1.0000000 | 0 | 0 | 0.7692308 | 0.2416702 | DUSP26 |
| 1320 | carbohydrate derivative biosynthetic process (GO:1901137) | 3/377 | 0.7304279 | 1.0000000 | 0 | 0 | 0.7957560 | 0.2499667 | NPPC;RAMP2;GPC3 |
| 1321 | cellular lipid catabolic process (GO:0044242) | 1/131 | 0.7331076 | 1.0000000 | 0 | 0 | 0.7633588 | 0.2369945 | ACOXL |
| 1322 | regulation of protein transport (GO:0051223) | 3/379 | 0.7337111 | 1.0000000 | 0 | 0 | 0.7915567 | 0.2450976 | PLA2G1B;CRTAM;OR51E2 |
| 1323 | signal transduction by p53 class mediator (GO:0072331) | 1/132 | 0.7357941 | 1.0000000 | 0 | 0 | 0.7575758 | 0.2324280 | ZNF385B |
| 1324 | negative regulation of protein phosphorylation (GO:0001933) | 2/260 | 0.7361780 | 1.0000000 | 0 | 0 | 0.7692308 | 0.2356026 | CAMK2N1;DUSP26 |
| 1325 | regulation of protein catabolic process (GO:0042176) | 2/260 | 0.7361780 | 1.0000000 | 0 | 0 | 0.7692308 | 0.2356026 | GJA1;GPC3 |
| 1326 | small molecule catabolic process (GO:0044282) | 2/261 | 0.7381112 | 1.0000000 | 0 | 0 | 0.7662835 | 0.2326903 | ACOXL;QPRT |
| 1327 | activation of MAPK activity (GO:0000187) | 1/133 | 0.7384537 | 1.0000000 | 0 | 0 | 0.7518797 | 0.2279676 | PLA2G1B |
| 1328 | humoral immune response (GO:0006959) | 2/263 | 0.7419414 | 1.0000000 | 0 | 0 | 0.7604563 | 0.2269848 | IGHG4;PLA2G1B |
| 1329 | pattern specification process (GO:0007389) | 3/385 | 0.7433729 | 1.0000000 | 0 | 0 | 0.7792208 | 0.2310837 | HHIP;GPC3;FEZF2 |
| 1330 | reproductive structure development (GO:0048608) | 2/265 | 0.7457238 | 1.0000000 | 0 | 0 | 0.7547170 | 0.2214339 | FGF9;PEG10 |
| 1331 | protein-DNA complex subunit organization (GO:0071824) | 1/136 | 0.7462737 | 1.0000000 | 0 | 0 | 0.7352941 | 0.2151933 | NAP1L3 |
| 1332 | regulation of cellular carbohydrate metabolic process (GO:0010675) | 1/137 | 0.7488283 | 1.0000000 | 0 | 0 | 0.7299270 | 0.2111281 | LEPR |
| 1333 | neuron projection development (GO:0031175) | 1/137 | 0.7488283 | 1.0000000 | 0 | 0 | 0.7299270 | 0.2111281 | FEZF2 |
| 1334 | regulation of ion transmembrane transporter activity (GO:0032412) | 1/137 | 0.7488283 | 1.0000000 | 0 | 0 | 0.7299270 | 0.2111281 | KCNJ1 |
| 1335 | regulation of nuclear division (GO:0051783) | 1/138 | 0.7513574 | 1.0000000 | 0 | 0 | 0.7246377 | 0.2071550 | DMRT1 |
| 1336 | positive regulation of peptidyl-tyrosine phosphorylation (GO:0050731) | 1/139 | 0.7538610 | 1.0000000 | 0 | 0 | 0.7194245 | 0.2032714 | CCL5 |
| 1337 | regulation of heart contraction (GO:0008016) | 1/140 | 0.7563396 | 1.0000000 | 0 | 0 | 0.7142857 | 0.1994748 | HOPX |
| 1338 | regulation of transmembrane transporter activity (GO:0022898) | 1/141 | 0.7587934 | 1.0000000 | 0 | 0 | 0.7092199 | 0.1957629 | KCNJ1 |
| 1339 | response to reactive oxygen species (GO:0000302) | 1/141 | 0.7587934 | 1.0000000 | 0 | 0 | 0.7092199 | 0.1957629 | SCGB1A1 |
| 1340 | regulation of MAP kinase activity (GO:0043405) | 2/273 | 0.7603837 | 1.0000000 | 0 | 0 | 0.7326007 | 0.2006829 | PLA2G1B;DIRAS2 |
| 1341 | response to alcohol (GO:0097305) | 2/274 | 0.7621641 | 1.0000000 | 0 | 0 | 0.7299270 | 0.1982434 | NPPC;RAMP2 |
| 1342 | neurotrophin TRK receptor signaling pathway (GO:0048011) | 2/274 | 0.7621641 | 1.0000000 | 0 | 0 | 0.7299270 | 0.1982434 | FGF9;FGF18 |
| 1343 | positive regulation of neuron projection development (GO:0010976) | 1/144 | 0.7660082 | 1.0000000 | 0 | 0 | 0.6944444 | 0.1851128 | ROBO2 |
| 1344 | regulation of carbohydrate metabolic process (GO:0006109) | 1/145 | 0.7683650 | 1.0000000 | 0 | 0 | 0.6896552 | 0.1817175 | LEPR |
| 1345 | neurotrophin signaling pathway (GO:0038179) | 2/278 | 0.7691720 | 1.0000000 | 0 | 0 | 0.7194245 | 0.1888062 | FGF9;FGF18 |
| 1346 | organ morphogenesis (GO:0009887) | 3/405 | 0.7735836 | 1.0000000 | 0 | 0 | 0.7407407 | 0.1901641 | HHIP;DLC1;TBX4 |
| 1347 | regulation of JNK cascade (GO:0046328) | 1/148 | 0.7752949 | 1.0000000 | 0 | 0 | 0.6756757 | 0.1719675 | FLT4 |
| 1348 | positive regulation of Rho GTPase activity (GO:0032321) | 1/149 | 0.7775586 | 1.0000000 | 0 | 0 | 0.6711409 | 0.1688565 | DLC1 |
| 1349 | positive regulation of neurogenesis (GO:0050769) | 2/283 | 0.7776798 | 1.0000000 | 0 | 0 | 0.7067138 | 0.1776964 | ROBO2;FEZF2 |
| 1350 | negative regulation of transferase activity (GO:0051348) | 2/284 | 0.7793483 | 1.0000000 | 0 | 0 | 0.7042254 | 0.1755614 | CAMK2N1;DUSP26 |
| 1351 | actin filament organization (GO:0007015) | 1/150 | 0.7797997 | 1.0000000 | 0 | 0 | 0.6666667 | 0.1658121 | PLA2G1B |
| 1352 | anterior/posterior pattern specification (GO:0009952) | 1/150 | 0.7797997 | 1.0000000 | 0 | 0 | 0.6666667 | 0.1658121 | FEZF2 |
| 1353 | negative regulation of cell growth (GO:0030308) | 1/150 | 0.7797997 | 1.0000000 | 0 | 0 | 0.6666667 | 0.1658121 | SCGB3A1 |
| 1354 | peptidyl-tyrosine phosphorylation (GO:0018108) | 1/152 | 0.7842147 | 1.0000000 | 0 | 0 | 0.6578947 | 0.1599160 | FLT4 |
| 1355 | maintenance of location (GO:0051235) | 1/152 | 0.7842147 | 1.0000000 | 0 | 0 | 0.6578947 | 0.1599160 | FBN1 |
| 1356 | G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger (GO:0007187) | 1/153 | 0.7863891 | 1.0000000 | 0 | 0 | 0.6535948 | 0.1570612 | MC4R |
| 1357 | regulation of transporter activity (GO:0032409) | 1/153 | 0.7863891 | 1.0000000 | 0 | 0 | 0.6535948 | 0.1570612 | KCNJ1 |
| 1358 | myeloid cell differentiation (GO:0030099) | 1/154 | 0.7885417 | 1.0000000 | 0 | 0 | 0.6493506 | 0.1542663 | GPC3 |
| 1359 | developmental maturation (GO:0021700) | 1/154 | 0.7885417 | 1.0000000 | 0 | 0 | 0.6493506 | 0.1542663 | GJA1 |
| 1360 | peptidyl-tyrosine modification (GO:0018212) | 1/154 | 0.7885417 | 1.0000000 | 0 | 0 | 0.6493506 | 0.1542663 | FLT4 |
| 1361 | cellular amino acid metabolic process (GO:0006520) | 3/421 | 0.7956155 | 1.0000000 | 0 | 0 | 0.7125891 | 0.1629258 | DDC;PLA2G1B;PADI3 |
| 1362 | hormone metabolic process (GO:0042445) | 1/158 | 0.7969382 | 1.0000000 | 0 | 0 | 0.6329114 | 0.1436570 | SCG5 |
| 1363 | Fc-epsilon receptor signaling pathway (GO:0038095) | 2/295 | 0.7969918 | 1.0000000 | 0 | 0 | 0.6779661 | 0.1538379 | FGF9;FGF18 |
| 1364 | regulation of extrinsic apoptotic signaling pathway (GO:2001236) | 1/161 | 0.8030171 | 1.0000000 | 0 | 0 | 0.6211180 | 0.1362604 | CX3CR1 |
| 1365 | protein dephosphorylation (GO:0006470) | 1/161 | 0.8030171 | 1.0000000 | 0 | 0 | 0.6211180 | 0.1362604 | DUSP26 |
| 1366 | complement activation, classical pathway (GO:0006958) | 1/162 | 0.8050029 | 1.0000000 | 0 | 0 | 0.6172840 | 0.1338947 | IGHG4 |
| 1367 | glycosaminoglycan metabolic process (GO:0030203) | 1/162 | 0.8050029 | 1.0000000 | 0 | 0 | 0.6172840 | 0.1338947 | GPC3 |
| 1368 | response to nutrient (GO:0007584) | 1/163 | 0.8069688 | 1.0000000 | 0 | 0 | 0.6134969 | 0.1315768 | ABCG2 |
| 1369 | actin filament-based process (GO:0030029) | 2/303 | 0.8090320 | 1.0000000 | 0 | 0 | 0.6600660 | 0.1398791 | DLC1;MYOZ1 |
| 1370 | cellular response to transforming growth factor beta stimulus (GO:0071560) | 1/166 | 0.8127489 | 1.0000000 | 0 | 0 | 0.6024096 | 0.1248994 | CX3CR1 |
| 1371 | response to estrogen (GO:0043627) | 1/166 | 0.8127489 | 1.0000000 | 0 | 0 | 0.6024096 | 0.1248994 | RAMP2 |
| 1372 | response to transforming growth factor beta (GO:0071559) | 1/166 | 0.8127489 | 1.0000000 | 0 | 0 | 0.6024096 | 0.1248994 | CX3CR1 |
| 1373 | regulation of vesicle-mediated transport (GO:0060627) | 2/306 | 0.8133814 | 1.0000000 | 0 | 0 | 0.6535948 | 0.1350034 | SFTPD;GPC3 |
| 1374 | response to wounding (GO:0009611) | 1/167 | 0.8146371 | 1.0000000 | 0 | 0 | 0.5988024 | 0.1227620 | CX3CR1 |
| 1375 | establishment of organelle localization (GO:0051656) | 1/168 | 0.8165063 | 1.0000000 | 0 | 0 | 0.5952381 | 0.1206671 | DDC |
| 1376 | positive regulation of I-kappaB kinase/NF-kappaB signaling (GO:0043123) | 1/168 | 0.8165063 | 1.0000000 | 0 | 0 | 0.5952381 | 0.1206671 | GJA1 |
| 1377 | regulation of insulin secretion (GO:0050796) | 1/169 | 0.8183568 | 1.0000000 | 0 | 0 | 0.5917160 | 0.1186135 | CCL5 |
| 1378 | regulation of stress-activated MAPK cascade (GO:0032872) | 1/170 | 0.8201887 | 1.0000000 | 0 | 0 | 0.5882353 | 0.1166005 | FLT4 |
| 1379 | protein autophosphorylation (GO:0046777) | 1/170 | 0.8201887 | 1.0000000 | 0 | 0 | 0.5882353 | 0.1166005 | FLT4 |
| 1380 | intrinsic apoptotic signaling pathway (GO:0097193) | 1/170 | 0.8201887 | 1.0000000 | 0 | 0 | 0.5882353 | 0.1166005 | ZNF385B |
| 1381 | regulation of establishment of protein localization (GO:0070201) | 3/442 | 0.8218049 | 1.0000000 | 0 | 0 | 0.6787330 | 0.1332029 | PLA2G1B;CRTAM;OR51E2 |
| 1382 | aminoglycan metabolic process (GO:0006022) | 1/171 | 0.8220022 | 1.0000000 | 0 | 0 | 0.5847953 | 0.1146270 | GPC3 |
| 1383 | regulation of stress-activated protein kinase signaling cascade (GO:0070302) | 1/171 | 0.8220022 | 1.0000000 | 0 | 0 | 0.5847953 | 0.1146270 | FLT4 |
| 1384 | positive regulation of nervous system development (GO:0051962) | 2/313 | 0.8231892 | 1.0000000 | 0 | 0 | 0.6389776 | 0.1243253 | ROBO2;FEZF2 |
| 1385 | regulation of Rho GTPase activity (GO:0032319) | 1/174 | 0.8273342 | 1.0000000 | 0 | 0 | 0.5747126 | 0.1089348 | DLC1 |
| 1386 | complement activation (GO:0006956) | 1/175 | 0.8290760 | 1.0000000 | 0 | 0 | 0.5714286 | 0.1071105 | IGHG4 |
| 1387 | response to mechanical stimulus (GO:0009612) | 1/176 | 0.8308003 | 1.0000000 | 0 | 0 | 0.5681818 | 0.1053215 | GJA1 |
| 1388 | cellular amide metabolic process (GO:0043603) | 1/177 | 0.8325073 | 1.0000000 | 0 | 0 | 0.5649718 | 0.1035668 | SCG5 |
| 1389 | glycerophospholipid biosynthetic process (GO:0046474) | 1/178 | 0.8341972 | 1.0000000 | 0 | 0 | 0.5617978 | 0.1018458 | PLA2G1B |
| 1390 | regulation of cell growth (GO:0001558) | 2/322 | 0.8351215 | 1.0000000 | 0 | 0 | 0.6211180 | 0.1119119 | SCGB3A1;ALOX12 |
| 1391 | nucleobase-containing compound transport (GO:0015931) | 1/180 | 0.8375262 | 1.0000000 | 0 | 0 | 0.5555556 | 0.0985015 | GJA1 |
| 1392 | positive regulation of protein kinase activity (GO:0045860) | 3/456 | 0.8376406 | 1.0000000 | 0 | 0 | 0.6578947 | 0.1165566 | PLA2G1B;CCL5;DIRAS2 |
| 1393 | negative regulation of phosphorylation (GO:0042326) | 2/325 | 0.8389352 | 1.0000000 | 0 | 0 | 0.6153846 | 0.1080750 | CAMK2N1;DUSP26 |
| 1394 | ATP catabolic process (GO:0006200) | 2/327 | 0.8414333 | 1.0000000 | 0 | 0 | 0.6116208 | 0.1055954 | KIF12;ABCG2 |
| 1395 | positive regulation of cytokine production (GO:0001819) | 2/327 | 0.8414333 | 1.0000000 | 0 | 0 | 0.6116208 | 0.1055954 | FLT4;CRTAM |
| 1396 | cellular response to external stimulus (GO:0071496) | 1/185 | 0.8455606 | 1.0000000 | 0 | 0 | 0.5405405 | 0.0906786 | GJA1 |
| 1397 | cellular component assembly involved in morphogenesis (GO:0010927) | 1/186 | 0.8471194 | 1.0000000 | 0 | 0 | 0.5376344 | 0.0892009 | MYOZ1 |
| 1398 | ribonucleoside monophosphate catabolic process (GO:0009158) | 2/332 | 0.8475264 | 1.0000000 | 0 | 0 | 0.6024096 | 0.0996586 | KIF12;ABCG2 |
| 1399 | purine ribonucleoside monophosphate catabolic process (GO:0009169) | 2/332 | 0.8475264 | 1.0000000 | 0 | 0 | 0.6024096 | 0.0996586 | KIF12;ABCG2 |
| 1400 | microtubule-based movement (GO:0007018) | 1/187 | 0.8486625 | 1.0000000 | 0 | 0 | 0.5347594 | 0.0877506 | KIF12 |
| 1401 | negative regulation of apoptotic signaling pathway (GO:2001234) | 1/187 | 0.8486625 | 1.0000000 | 0 | 0 | 0.5347594 | 0.0877506 | CX3CR1 |
| 1402 | purine nucleoside monophosphate catabolic process (GO:0009128) | 2/333 | 0.8487194 | 1.0000000 | 0 | 0 | 0.6006006 | 0.0985145 | KIF12;ABCG2 |
| 1403 | nucleoside monophosphate catabolic process (GO:0009125) | 2/335 | 0.8510799 | 1.0000000 | 0 | 0 | 0.5970149 | 0.0962682 | KIF12;ABCG2 |
| 1404 | regulation of peptidyl-tyrosine phosphorylation (GO:0050730) | 1/189 | 0.8517025 | 1.0000000 | 0 | 0 | 0.5291005 | 0.0849302 | CCL5 |
| 1405 | coagulation (GO:0050817) | 3/472 | 0.8542469 | 1.0000000 | 0 | 0 | 0.6355932 | 0.1001282 | SCUBE1;PROS1;JAM2 |
| 1406 | blood coagulation (GO:0007596) | 3/472 | 0.8542469 | 1.0000000 | 0 | 0 | 0.6355932 | 0.1001282 | SCUBE1;PROS1;JAM2 |
| 1407 | regulation of sequence-specific DNA binding transcription factor activity (GO:0051090) | 2/338 | 0.8545582 | 1.0000000 | 0 | 0 | 0.5917160 | 0.0930004 | BEX1;PLA2G1B |
| 1408 | negative regulation of cellular component organization (GO:0051129) | 3/474 | 0.8562155 | 1.0000000 | 0 | 0 | 0.6329114 | 0.0982488 | ROBO2;DMRT1;DLC1 |
| 1409 | hemostasis (GO:0007599) | 3/478 | 0.8600836 | 1.0000000 | 0 | 0 | 0.6276151 | 0.0945977 | SCUBE1;PROS1;JAM2 |
| 1410 | muscle contraction (GO:0006936) | 1/195 | 0.8604625 | 1.0000000 | 0 | 0 | 0.5128205 | 0.0770693 | GJA1 |
| 1411 | DNA recombination (GO:0006310) | 1/196 | 0.8618716 | 1.0000000 | 0 | 0 | 0.5102041 | 0.0758413 | MEIOB |
| 1412 | protein activation cascade (GO:0072376) | 1/196 | 0.8618716 | 1.0000000 | 0 | 0 | 0.5102041 | 0.0758413 | IGHG4 |
| 1413 | coenzyme metabolic process (GO:0006732) | 1/196 | 0.8618716 | 1.0000000 | 0 | 0 | 0.5102041 | 0.0758413 | QPRT |
| 1414 | positive regulation of kinase activity (GO:0033674) | 3/480 | 0.8619834 | 1.0000000 | 0 | 0 | 0.6250000 | 0.0928245 | PLA2G1B;CCL5;DIRAS2 |
| 1415 | negative regulation of intracellular signal transduction (GO:1902532) | 2/345 | 0.8623889 | 1.0000000 | 0 | 0 | 0.5797101 | 0.0858254 | DLC1;DUSP26 |
| 1416 | positive regulation of response to external stimulus (GO:0032103) | 1/201 | 0.8687075 | 1.0000000 | 0 | 0 | 0.4975124 | 0.0700243 | CCL5 |
| 1417 | glycerolipid biosynthetic process (GO:0045017) | 1/202 | 0.8700337 | 1.0000000 | 0 | 0 | 0.4950495 | 0.0689224 | PLA2G1B |
| 1418 | immune response-regulating cell surface receptor signaling pathway involved in phagocytosis (GO:0002433) | 1/203 | 0.8713466 | 1.0000000 | 0 | 0 | 0.4926108 | 0.0678401 | IGHG4 |
| 1419 | Fc-gamma receptor signaling pathway involved in phagocytosis (GO:0038096) | 1/203 | 0.8713466 | 1.0000000 | 0 | 0 | 0.4926108 | 0.0678401 | IGHG4 |
| 1420 | Fc-gamma receptor signaling pathway (GO:0038094) | 1/203 | 0.8713466 | 1.0000000 | 0 | 0 | 0.4926108 | 0.0678401 | IGHG4 |
| 1421 | lipid biosynthetic process (GO:0008610) | 3/491 | 0.8720349 | 1.0000000 | 0 | 0 | 0.6109980 | 0.0836614 | CH25H;PLA2G1B;ALOX12 |
| 1422 | cell morphogenesis (GO:0000902) | 1/204 | 0.8726464 | 1.0000000 | 0 | 0 | 0.4901961 | 0.0667769 | DMRT1 |
| 1423 | nucleocytoplasmic transport (GO:0006913) | 1/204 | 0.8726464 | 1.0000000 | 0 | 0 | 0.4901961 | 0.0667769 | FGF9 |
| 1424 | Fc receptor mediated stimulatory signaling pathway (GO:0002431) | 1/204 | 0.8726464 | 1.0000000 | 0 | 0 | 0.4901961 | 0.0667769 | IGHG4 |
| 1425 | chromosome organization (GO:0051276) | 1/204 | 0.8726464 | 1.0000000 | 0 | 0 | 0.4901961 | 0.0667769 | MEIOB |
| 1426 | platelet activation (GO:0030168) | 1/205 | 0.8739330 | 1.0000000 | 0 | 0 | 0.4878049 | 0.0657325 | PROS1 |
| 1427 | phospholipid biosynthetic process (GO:0008654) | 1/206 | 0.8752067 | 1.0000000 | 0 | 0 | 0.4854369 | 0.0647064 | PLA2G1B |
| 1428 | positive regulation of cell development (GO:0010720) | 2/358 | 0.8759198 | 1.0000000 | 0 | 0 | 0.5586592 | 0.0740116 | ROBO2;FEZF2 |
| 1429 | nuclear transport (GO:0051169) | 1/209 | 0.8789515 | 1.0000000 | 0 | 0 | 0.4784689 | 0.0617347 | FGF9 |
| 1430 | single-organism behavior (GO:0044708) | 2/362 | 0.8798311 | 1.0000000 | 0 | 0 | 0.5524862 | 0.0707322 | SNCG;GRIK1 |
| 1431 | regulation of leukocyte differentiation (GO:1902105) | 1/210 | 0.8801748 | 1.0000000 | 0 | 0 | 0.4761905 | 0.0607785 | HLA-DOA |
| 1432 | post-translational protein modification (GO:0043687) | 1/211 | 0.8813857 | 1.0000000 | 0 | 0 | 0.4739336 | 0.0598388 | PROS1 |
| 1433 | negative regulation of nervous system development (GO:0051961) | 1/211 | 0.8813857 | 1.0000000 | 0 | 0 | 0.4739336 | 0.0598388 | ROBO2 |
| 1434 | regulation of I-kappaB kinase/NF-kappaB signaling (GO:0043122) | 1/213 | 0.8837712 | 1.0000000 | 0 | 0 | 0.4694836 | 0.0580080 | GJA1 |
| 1435 | alpha-amino acid metabolic process (GO:1901605) | 1/213 | 0.8837712 | 1.0000000 | 0 | 0 | 0.4694836 | 0.0580080 | PADI3 |
| 1436 | positive regulation of intracellular transport (GO:0032388) | 1/217 | 0.8883999 | 1.0000000 | 0 | 0 | 0.4608295 | 0.0545315 | PLA2G1B |
| 1437 | positive regulation of cell cycle process (GO:0090068) | 1/220 | 0.8917506 | 1.0000000 | 0 | 0 | 0.4545455 | 0.0520767 | DMRT1 |
| 1438 | ATP metabolic process (GO:0046034) | 2/377 | 0.8935096 | 1.0000000 | 0 | 0 | 0.5305040 | 0.0597338 | KIF12;ABCG2 |
| 1439 | in utero embryonic development (GO:0001701) | 1/222 | 0.8939287 | 1.0000000 | 0 | 0 | 0.4504505 | 0.0505087 | GJA1 |
| 1440 | regulation of neuron death (GO:1901214) | 1/225 | 0.8971142 | 1.0000000 | 0 | 0 | 0.4444444 | 0.0482543 | CCL5 |
| 1441 | chordate embryonic development (GO:0043009) | 1/226 | 0.8981547 | 1.0000000 | 0 | 0 | 0.4424779 | 0.0475278 | GJA1 |
| 1442 | cognition (GO:0050890) | 1/227 | 0.8991848 | 1.0000000 | 0 | 0 | 0.4405286 | 0.0468135 | TMPRSS11E |
| 1443 | glycerophospholipid metabolic process (GO:0006650) | 1/229 | 0.9012140 | 1.0000000 | 0 | 0 | 0.4366812 | 0.0454203 | PLA2G1B |
| 1444 | embryo development ending in birth or egg hatching (GO:0009792) | 1/230 | 0.9022132 | 1.0000000 | 0 | 0 | 0.4347826 | 0.0447410 | GJA1 |
| 1445 | nucleic acid phosphodiester bond hydrolysis (GO:0090305) | 1/230 | 0.9022132 | 1.0000000 | 0 | 0 | 0.4347826 | 0.0447410 | MEIOB |
| 1446 | regulation of anatomical structure size (GO:0090066) | 1/232 | 0.9041817 | 1.0000000 | 0 | 0 | 0.4310345 | 0.0434159 | NPPC |
| 1447 | regulation of cell projection organization (GO:0031344) | 2/391 | 0.9049630 | 1.0000000 | 0 | 0 | 0.5115090 | 0.0510799 | ROBO2;GPM6A |
| 1448 | muscle system process (GO:0003012) | 1/237 | 0.9089322 | 1.0000000 | 0 | 0 | 0.4219409 | 0.0402890 | GJA1 |
| 1449 | negative regulation of cell development (GO:0010721) | 1/239 | 0.9107660 | 1.0000000 | 0 | 0 | 0.4184100 | 0.0391085 | NPPC |
| 1450 | regulation of actin cytoskeleton organization (GO:0032956) | 1/240 | 0.9116691 | 1.0000000 | 0 | 0 | 0.4166667 | 0.0385326 | DLC1 |
| 1451 | purine ribonucleoside monophosphate metabolic process (GO:0009167) | 2/402 | 0.9131472 | 1.0000000 | 0 | 0 | 0.4975124 | 0.0452031 | KIF12;ABCG2 |
| 1452 | purine nucleoside monophosphate metabolic process (GO:0009126) | 2/403 | 0.9138576 | 1.0000000 | 0 | 0 | 0.4962779 | 0.0447050 | KIF12;ABCG2 |
| 1453 | GTP catabolic process (GO:0006184) | 1/243 | 0.9143243 | 1.0000000 | 0 | 0 | 0.4115226 | 0.0368601 | DIRAS2 |
| 1454 | regulation of neuron differentiation (GO:0045664) | 2/405 | 0.9152623 | 1.0000000 | 0 | 0 | 0.4938272 | 0.0437257 | ROBO2;FEZF2 |
| 1455 | regulation of lipid metabolic process (GO:0019216) | 1/245 | 0.9160501 | 1.0000000 | 0 | 0 | 0.4081633 | 0.0357895 | FABP3 |
| 1456 | negative regulation of protein modification process (GO:0031400) | 2/407 | 0.9166456 | 1.0000000 | 0 | 0 | 0.4914005 | 0.0427687 | CAMK2N1;DUSP26 |
| 1457 | guanosine-containing compound catabolic process (GO:1901069) | 1/246 | 0.9169000 | 1.0000000 | 0 | 0 | 0.4065041 | 0.0352670 | DIRAS2 |
| 1458 | regulation of cell morphogenesis (GO:0022604) | 2/408 | 0.9173293 | 1.0000000 | 0 | 0 | 0.4901961 | 0.0422984 | ROBO2;DLC1 |
| 1459 | regulation of cell morphogenesis involved in differentiation (GO:0010769) | 1/248 | 0.9185742 | 1.0000000 | 0 | 0 | 0.4032258 | 0.0342470 | ROBO2 |
| 1460 | positive regulation of cellular component biogenesis (GO:0044089) | 1/249 | 0.9193986 | 1.0000000 | 0 | 0 | 0.4016064 | 0.0337492 | GPM6A |
| 1461 | leukocyte differentiation (GO:0002521) | 1/251 | 0.9210227 | 1.0000000 | 0 | 0 | 0.3984064 | 0.0327771 | GPC3 |
| 1462 | activation of protein kinase activity (GO:0032147) | 1/252 | 0.9218225 | 1.0000000 | 0 | 0 | 0.3968254 | 0.0323026 | PLA2G1B |
| 1463 | ribonucleoside monophosphate metabolic process (GO:0009161) | 2/416 | 0.9226129 | 1.0000000 | 0 | 0 | 0.4807692 | 0.0387238 | KIF12;ABCG2 |
| 1464 | regulation of protein serine/threonine kinase activity (GO:0071900) | 2/416 | 0.9226129 | 1.0000000 | 0 | 0 | 0.4807692 | 0.0387238 | PLA2G1B;DIRAS2 |
| 1465 | negative regulation of cell cycle process (GO:0010948) | 1/254 | 0.9233980 | 1.0000000 | 0 | 0 | 0.3937008 | 0.0313760 | DMRT1 |
| 1466 | cofactor metabolic process (GO:0051186) | 1/255 | 0.9241738 | 1.0000000 | 0 | 0 | 0.3921569 | 0.0309236 | QPRT |
| 1467 | cellular protein complex assembly (GO:0043623) | 1/256 | 0.9249419 | 1.0000000 | 0 | 0 | 0.3906250 | 0.0304783 | CCL5 |
| 1468 | regulation of small GTPase mediated signal transduction (GO:0051056) | 1/256 | 0.9249419 | 1.0000000 | 0 | 0 | 0.3906250 | 0.0304783 | DLC1 |
| 1469 | regulation of actin filament-based process (GO:0032970) | 1/257 | 0.9257022 | 1.0000000 | 0 | 0 | 0.3891051 | 0.0300400 | DLC1 |
| 1470 | GTP metabolic process (GO:0046039) | 1/258 | 0.9264548 | 1.0000000 | 0 | 0 | 0.3875969 | 0.0296085 | DIRAS2 |
| 1471 | nucleoside monophosphate metabolic process (GO:0009123) | 2/427 | 0.9293624 | 1.0000000 | 0 | 0 | 0.4683841 | 0.0343122 | KIF12;ABCG2 |
| 1472 | regulation of translation (GO:0006417) | 1/264 | 0.9308139 | 1.0000000 | 0 | 0 | 0.3787879 | 0.0271575 | CCL5 |
| 1473 | protein glycosylation (GO:0006486) | 1/264 | 0.9308139 | 1.0000000 | 0 | 0 | 0.3787879 | 0.0271575 | ST6GAL2 |
| 1474 | macromolecule glycosylation (GO:0043413) | 1/264 | 0.9308139 | 1.0000000 | 0 | 0 | 0.3787879 | 0.0271575 | ST6GAL2 |
| 1475 | negative regulation of cell cycle (GO:0045786) | 2/430 | 0.9311049 | 1.0000000 | 0 | 0 | 0.4651163 | 0.0332016 | NPPC;DMRT1 |
| 1476 | guanosine-containing compound metabolic process (GO:1901068) | 1/269 | 0.9342494 | 1.0000000 | 0 | 0 | 0.3717472 | 0.0252832 | DIRAS2 |
| 1477 | posttranscriptional regulation of gene expression (GO:0010608) | 2/438 | 0.9355556 | 1.0000000 | 0 | 0 | 0.4566210 | 0.0304177 | CCL5;SCGB1A1 |
| 1478 | small GTPase mediated signal transduction (GO:0007264) | 2/439 | 0.9360924 | 1.0000000 | 0 | 0 | 0.4555809 | 0.0300870 | DLC1;DIRAS2 |
| 1479 | glycosylation (GO:0070085) | 1/273 | 0.9368751 | 1.0000000 | 0 | 0 | 0.3663004 | 0.0238847 | ST6GAL2 |
| 1480 | regulation of neuron projection development (GO:0010975) | 1/275 | 0.9381486 | 1.0000000 | 0 | 0 | 0.3636364 | 0.0232171 | ROBO2 |
| 1481 | embryo development (GO:0009790) | 1/276 | 0.9387757 | 1.0000000 | 0 | 0 | 0.3623188 | 0.0228908 | GJA1 |
| 1482 | protein localization to membrane (GO:0072657) | 1/276 | 0.9387757 | 1.0000000 | 0 | 0 | 0.3623188 | 0.0228908 | RAMP2 |
| 1483 | organelle assembly (GO:0070925) | 1/278 | 0.9400110 | 1.0000000 | 0 | 0 | 0.3597122 | 0.0222531 | MYOZ1 |
| 1484 | positive regulation of cell cycle (GO:0045787) | 1/278 | 0.9400110 | 1.0000000 | 0 | 0 | 0.3597122 | 0.0222531 | DMRT1 |
| 1485 | dephosphorylation (GO:0016311) | 1/278 | 0.9400110 | 1.0000000 | 0 | 0 | 0.3597122 | 0.0222531 | DUSP26 |
| 1486 | sensory perception (GO:0007600) | 2/457 | 0.9450631 | 1.0000000 | 0 | 0 | 0.4376368 | 0.0247281 | OPN1SW;CNGA1 |
| 1487 | phospholipid metabolic process (GO:0006644) | 1/288 | 0.9458253 | 1.0000000 | 0 | 0 | 0.3472222 | 0.0193394 | PLA2G1B |
| 1488 | response to oxidative stress (GO:0006979) | 1/290 | 0.9469190 | 1.0000000 | 0 | 0 | 0.3448276 | 0.0188075 | SCGB1A1 |
| 1489 | response to nutrient levels (GO:0031667) | 1/291 | 0.9474576 | 1.0000000 | 0 | 0 | 0.3436426 | 0.0185474 | ABCG2 |
| 1490 | establishment of protein localization to organelle (GO:0072594) | 1/292 | 0.9479908 | 1.0000000 | 0 | 0 | 0.3424658 | 0.0182913 | FGF9 |
| 1491 | positive regulation of Ras GTPase activity (GO:0032320) | 1/292 | 0.9479908 | 1.0000000 | 0 | 0 | 0.3424658 | 0.0182913 | DLC1 |
| 1492 | histone modification (GO:0016570) | 1/293 | 0.9485186 | 1.0000000 | 0 | 0 | 0.3412969 | 0.0180389 | HOPX |
| 1493 | covalent chromatin modification (GO:0016569) | 1/296 | 0.9500701 | 1.0000000 | 0 | 0 | 0.3378378 | 0.0173039 | HOPX |
| 1494 | glycerolipid metabolic process (GO:0046486) | 1/296 | 0.9500701 | 1.0000000 | 0 | 0 | 0.3378378 | 0.0173039 | PLA2G1B |
| 1495 | nuclear division (GO:0000280) | 1/298 | 0.9510786 | 1.0000000 | 0 | 0 | 0.3355705 | 0.0168317 | MEIOB |
| 1496 | response to extracellular stimulus (GO:0009991) | 1/313 | 0.9580230 | 1.0000000 | 0 | 0 | 0.3194888 | 0.0137008 | ABCG2 |
| 1497 | sulfur compound metabolic process (GO:0006790) | 1/314 | 0.9584494 | 1.0000000 | 0 | 0 | 0.3184713 | 0.0135154 | GPC3 |
| 1498 | multicellular organismal reproductive process (GO:0048609) | 2/491 | 0.9588501 | 1.0000000 | 0 | 0 | 0.4073320 | 0.0171163 | DMRT1;ABCG2 |
| 1499 | single-organism cellular localization (GO:1902580) | 2/496 | 0.9605755 | 1.0000000 | 0 | 0 | 0.4032258 | 0.0162188 | RAMP2;FGF9 |
| 1500 | organelle fission (GO:0048285) | 1/325 | 0.9628649 | 1.0000000 | 0 | 0 | 0.3076923 | 0.0116437 | MEIOB |
| 1501 | apoptotic signaling pathway (GO:0097190) | 1/327 | 0.9636160 | 1.0000000 | 0 | 0 | 0.3058104 | 0.0113341 | ZNF385B |
| 1502 | positive regulation of organelle organization (GO:0010638) | 1/340 | 0.9681429 | 1.0000000 | 0 | 0 | 0.2941176 | 0.0095222 | DMRT1 |
| 1503 | regulation of Ras GTPase activity (GO:0032318) | 1/349 | 0.9709441 | 1.0000000 | 0 | 0 | 0.2865330 | 0.0084488 | DLC1 |
| 1504 | regulation of cytoskeleton organization (GO:0051493) | 1/350 | 0.9712398 | 1.0000000 | 0 | 0 | 0.2857143 | 0.0083377 | DLC1 |
| 1505 | cellular component disassembly (GO:0022411) | 1/350 | 0.9712398 | 1.0000000 | 0 | 0 | 0.2857143 | 0.0083377 | FBN1 |
| 1506 | spermatogenesis (GO:0007283) | 1/353 | 0.9721090 | 1.0000000 | 0 | 0 | 0.2832861 | 0.0080134 | DMRT1 |
| 1507 | male gamete generation (GO:0048232) | 1/354 | 0.9723929 | 1.0000000 | 0 | 0 | 0.2824859 | 0.0079083 | DMRT1 |
| 1508 | regulation of apoptotic signaling pathway (GO:2001233) | 1/356 | 0.9729521 | 1.0000000 | 0 | 0 | 0.2808989 | 0.0077024 | CX3CR1 |
| 1509 | gamete generation (GO:0007276) | 1/390 | 0.9809052 | 1.0000000 | 0 | 0 | 0.2564103 | 0.0049435 | DMRT1 |
| 1510 | regulation of mitotic cell cycle (GO:0007346) | 1/391 | 0.9810999 | 1.0000000 | 0 | 0 | 0.2557545 | 0.0048800 | DMRT1 |
| 1511 | regulation of intracellular transport (GO:0032386) | 1/394 | 0.9816723 | 1.0000000 | 0 | 0 | 0.2538071 | 0.0046949 | PLA2G1B |
| 1512 | protein localization to organelle (GO:0033365) | 1/396 | 0.9820443 | 1.0000000 | 0 | 0 | 0.2525253 | 0.0045755 | FGF9 |
| 1513 | mRNA processing (GO:0006397) | 1/397 | 0.9822274 | 1.0000000 | 0 | 0 | 0.2518892 | 0.0045170 | APOBEC2 |
| 1514 | DNA repair (GO:0006281) | 1/403 | 0.9832880 | 1.0000000 | 0 | 0 | 0.2481390 | 0.0041819 | MEIOB |
| 1515 | regulation of cellular response to stress (GO:0080135) | 1/404 | 0.9834585 | 1.0000000 | 0 | 0 | 0.2475248 | 0.0041287 | FLT4 |
| 1516 | detection of chemical stimulus involved in sensory perception of smell (GO:0050911) | 1/420 | 0.9859630 | 1.0000000 | 0 | 0 | 0.2380952 | 0.0033658 | OR51E2 |
| 1517 | microtubule-based process (GO:0007017) | 1/437 | 0.9882116 | 1.0000000 | 0 | 0 | 0.2288330 | 0.0027136 | KIF12 |
| 1518 | detection of chemical stimulus involved in sensory perception (GO:0050907) | 1/465 | 0.9911602 | 1.0000000 | 0 | 0 | 0.2150538 | 0.0019095 | OR51E2 |
| 1519 | transcription from RNA polymerase II promoter (GO:0006366) | 1/470 | 0.9916034 | 1.0000000 | 0 | 0 | 0.2127660 | 0.0017940 | HLF |
| 1520 | chromatin modification (GO:0016568) | 1/475 | 0.9920246 | 1.0000000 | 0 | 0 | 0.2105263 | 0.0016858 | HOPX |
| 1521 | regulation of cell cycle process (GO:0010564) | 1/481 | 0.9925023 | 1.0000000 | 0 | 0 | 0.2079002 | 0.0015647 | DMRT1 |
| 1522 | positive regulation of GTPase activity (GO:0043547) | 1/482 | 0.9925791 | 1.0000000 | 0 | 0 | 0.2074689 | 0.0015454 | DLC1 |
| 1523 | positive regulation of GTP catabolic process (GO:0033126) | 1/483 | 0.9926551 | 1.0000000 | 0 | 0 | 0.2070393 | 0.0015263 | DLC1 |
| 1524 | detection of chemical stimulus (GO:0009593) | 1/499 | 0.9937711 | 1.0000000 | 0 | 0 | 0.2004008 | 0.0012522 | OR51E2 |
go_cellular %>%
knitr::kable(
format = "html", align = rep("c", ncol(go_cellular) + 1),
row.names = TRUE
) %>%
kableExtra::kable_styling() %>%
kableExtra::scroll_box(height = "300px")
| Term | Overlap | P.value | Adjusted.P.value | Old.P.value | Old.Adjusted.P.value | Odds.Ratio | Combined.Score | Genes | |
|---|---|---|---|---|---|---|---|---|---|
| 1 | integral component of plasma membrane (GO:0005887) | 26/1066 | 0.0000240 | 0.0153709 | 0 | 0 | 2.4390244 | 25.9470911 | CX3CR1;RAMP2;HHIP;FLT4;GRIK1;GJA1;KLRK1;TSPAN7;GPC3;CNGA1;GABRD;JAM2;CLCA4;TRGC2;TMPRSS11A;CD52;GABBR2;SLC6A13;SYT13;TMPRSS11E;TMPRSS11F;OPN1SW;CD8B;BPI;LGR5;KCNK3 |
| 2 | proteinaceous extracellular matrix (GO:0005578) | 8/239 | 0.0028629 | 0.9175744 | 0 | 0 | 3.3472803 | 19.6013520 | ADAMTSL1;SMOC2;ECM2;SFTPD;GPC3;SPARCL1;EMID1;FBN1 |
| 3 | microfibril (GO:0001527) | 2/9 | 0.0034202 | 0.7307895 | 0 | 0 | 22.2222222 | 126.1788209 | MFAP4;FBN1 |
| 4 | voltage-gated potassium channel complex (GO:0008076) | 4/70 | 0.0053199 | 0.8525140 | 0 | 0 | 5.7142857 | 29.9217183 | KCNJ6;KCNA3;KCNA4;KCNJ1 |
| 5 | potassium channel complex (GO:0034705) | 4/71 | 0.0055942 | 0.7171766 | 0 | 0 | 5.6338028 | 29.2170409 | KCNJ6;KCNA3;KCNA4;KCNJ1 |
| 6 | receptor complex (GO:0043235) | 8/272 | 0.0061980 | 0.6621583 | 0 | 0 | 2.9411765 | 14.9515311 | GABBR2;RAMP2;CD8B;GRID1;FLT4;LEPR;GRIK1;LRP1B |
| 7 | fibril (GO:0043205) | 2/13 | 0.0072181 | 0.6609718 | 0 | 0 | 15.3846154 | 75.8640519 | MFAP4;FBN1 |
| 8 | extracellular matrix (GO:0031012) | 9/348 | 0.0085495 | 0.6850315 | 0 | 0 | 2.5862069 | 12.3152028 | ADAMTSL1;SMOC2;MFAP4;ECM2;SFTPD;GPC3;SPARCL1;EMID1;FBN1 |
| 9 | interstitial matrix (GO:0005614) | 2/15 | 0.0095900 | 0.6830217 | 0 | 0 | 13.3333333 | 61.9604467 | SMOC2;ECM2 |
| 10 | photoreceptor outer segment membrane (GO:0042622) | 2/16 | 0.0108884 | 0.6979480 | 0 | 0 | 12.5000000 | 56.5006873 | OPN1SW;CNGA1 |
| 11 | MHC class II protein complex (GO:0042613) | 2/18 | 0.0137022 | 0.7984648 | 0 | 0 | 11.1111111 | 47.6688727 | HLA-DOA;HLA-DQB2 |
| 12 | postsynaptic membrane (GO:0045211) | 6/195 | 0.0138327 | 0.7388954 | 0 | 0 | 3.0769231 | 13.1714514 | CNKSR2;GABBR2;CAMK2N1;GRID1;GRIK1;GABRD |
| 13 | extrinsic component of plasma membrane (GO:0019897) | 3/52 | 0.0152014 | 0.7495468 | 0 | 0 | 5.7692308 | 24.1521154 | SCUBE1;MYZAP;TGM3 |
| 14 | ion channel complex (GO:0034702) | 7/258 | 0.0153427 | 0.7024774 | 0 | 0 | 2.7131783 | 11.3332554 | KCNJ6;GRID1;KCNA3;KCNA4;GRIK1;GABRD;KCNJ1 |
| 15 | neuronal cell body (GO:0043025) | 7/270 | 0.0191830 | 0.8197530 | 0 | 0 | 2.5925926 | 10.2504148 | CNKSR2;KISS1;SLC5A7;GPM6A;DDC;CAMK2N1;SNCG |
| 16 | multivesicular body (GO:0005771) | 2/23 | 0.0219305 | 0.8785902 | 0 | 0 | 8.6956522 | 33.2163252 | GJA1;HLA-DQB2 |
| 17 | transmembrane transporter complex (GO:1902495) | 7/286 | 0.0252891 | 0.9535466 | 0 | 0 | 2.4475524 | 9.0005880 | KCNJ6;GRID1;KCNA3;KCNA4;GRIK1;GABRD;KCNJ1 |
| 18 | synaptic membrane (GO:0097060) | 6/228 | 0.0273927 | 0.9754837 | 0 | 0 | 2.6315789 | 9.4670514 | CNKSR2;GABBR2;CAMK2N1;GRID1;GRIK1;GABRD |
| 19 | transporter complex (GO:1990351) | 7/291 | 0.0274425 | 0.9258227 | 0 | 0 | 2.4054983 | 8.6493612 | KCNJ6;GRID1;KCNA3;KCNA4;GRIK1;GABRD;KCNJ1 |
| 20 | extrinsic component of cytoplasmic side of plasma membrane (GO:0031234) | 2/26 | 0.0276272 | 0.8854512 | 0 | 0 | 7.6923077 | 27.6073469 | MYZAP;TGM3 |
| 21 | cell surface (GO:0009986) | 9/437 | 0.0321362 | 0.9809188 | 0 | 0 | 2.0594966 | 7.0800809 | ROBO2;RAMP2;KLRK1;SCUBE1;KRT4;PLA2G1B;HHIP;ANXA9;GPR124 |
| 22 | extracellular space (GO:0005615) | 18/1120 | 0.0321818 | 0.9376619 | 0 | 0 | 1.6071429 | 5.5227100 | PLA2G1B;PROS1;A2ML1;SOGA3;SLURP1;KISS1;IGHG4;NPPC;FABP3;SCUBE1;FGF9;CCL5;FGF18;SCGB1A1;SPARCL1;SCGB3A1;KIAA0408;FBN1 |
| 23 | MHC protein complex (GO:0042611) | 2/29 | 0.0338475 | 0.9433138 | 0 | 0 | 6.8965517 | 23.3509763 | HLA-DOA;HLA-DQB2 |
| 24 | clathrin-coated endocytic vesicle membrane (GO:0030669) | 2/31 | 0.0382674 | 1.0000000 | 0 | 0 | 6.4516129 | 21.0526212 | CD207;HLA-DQB2 |
| 25 | extracellular matrix part (GO:0044420) | 4/127 | 0.0388027 | 0.9949012 | 0 | 0 | 3.1496063 | 10.2339070 | MFAP4;SMOC2;FGF9;FBN1 |
| 26 | cell body (GO:0044297) | 7/315 | 0.0395159 | 0.9742195 | 0 | 0 | 2.2222222 | 7.1801146 | CNKSR2;KISS1;SLC5A7;GPM6A;DDC;CAMK2N1;SNCG |
| 27 | basement membrane (GO:0005604) | 3/77 | 0.0420316 | 0.9978620 | 0 | 0 | 3.8961039 | 12.3480501 | SMOC2;FGF9;FBN1 |
| 28 | synapse part (GO:0044456) | 8/395 | 0.0456112 | 1.0000000 | 0 | 0 | 2.0253165 | 6.2533689 | CNKSR2;GABBR2;DDC;CAMK2N1;GRID1;GRIK1;GABRD;PPFIA2 |
| 29 | extracellular region (GO:0005576) | 23/1585 | 0.0456295 | 1.0000000 | 0 | 0 | 1.4511041 | 4.4798508 | TMPRSS11A;PCOLCE2;PLA2G1B;HHIP;PROS1;FLT4;SFTPD;PRSS27;A2ML1;TMPRSS11E;TMPRSS11F;SLURP1;KISS1;IGHG4;MFAP4;FGF9;CD8B;CCL5;FGF18;LEPR;SCG5;HCG22;FBN1 |
| 30 | early endosome membrane (GO:0031901) | 2/39 | 0.0579156 | 1.0000000 | 0 | 0 | 5.1282051 | 14.6090715 | CD8B;CD207 |
| 31 | cation channel complex (GO:0034703) | 4/147 | 0.0603096 | 1.0000000 | 0 | 0 | 2.7210884 | 7.6415355 | KCNJ6;KCNA3;KCNA4;KCNJ1 |
| 32 | trans-Golgi network membrane (GO:0032588) | 2/42 | 0.0660116 | 1.0000000 | 0 | 0 | 4.7619048 | 12.9424984 | LGR5;HLA-DQB2 |
| 33 | extracellular vesicular exosome (GO:0070062) | 35/2717 | 0.0677648 | 1.0000000 | 0 | 0 | 1.2881855 | 3.4674249 | ROBO2;GPM6A;DDC;PCOLCE2;PROS1;QPRT;KIF12;ALOX12;SEC14L3;IGHG4;ISLR;GJA1;FGF9;GPC3;SNCG;ANXA9;TGM3;CLCA4;PPFIA2;GRID1;SLC6A13;A2ML1;CYS1;CNFN;DUSP26;SLURP1;CNKSR2;MFAP4;FABP3;SCGB1A1;SPARCL1;SCGB3A1;BPI;ZNF114;FBN1 |
| 34 | ciliary membrane (GO:0060170) | 2/43 | 0.0687896 | 1.0000000 | 0 | 0 | 4.6511628 | 12.4497769 | OPN1SW;CNGA1 |
| 35 | neuronal cell body membrane (GO:0032809) | 1/8 | 0.0772681 | 1.0000000 | 0 | 0 | 12.5000000 | 32.0059307 | CX3CR1 |
| 36 | cell body membrane (GO:0044298) | 1/8 | 0.0772681 | 1.0000000 | 0 | 0 | 12.5000000 | 32.0059307 | CX3CR1 |
| 37 | clathrin-coated vesicle membrane (GO:0030665) | 2/48 | 0.0832284 | 1.0000000 | 0 | 0 | 4.1666667 | 10.3590263 | CD207;HLA-DQB2 |
| 38 | ionotropic glutamate receptor complex (GO:0008328) | 2/49 | 0.0862189 | 1.0000000 | 0 | 0 | 4.0816327 | 10.0035323 | GRID1;GRIK1 |
| 39 | secretory granule (GO:0030141) | 4/176 | 0.1005270 | 1.0000000 | 0 | 0 | 2.2727273 | 5.2212019 | NPPC;PLA2G1B;SCGB1A1;SCG5 |
| 40 | plasma membrane region (GO:0098590) | 7/395 | 0.1023945 | 1.0000000 | 0 | 0 | 1.7721519 | 4.0385962 | KISS1;GJA1;OPN1SW;DLC1;SLC4A10;CNGA1;ABCG2 |
| 41 | extrinsic component of membrane (GO:0019898) | 3/115 | 0.1084360 | 1.0000000 | 0 | 0 | 2.6086957 | 5.7954655 | SCUBE1;MYZAP;TGM3 |
| 42 | Golgi-associated vesicle membrane (GO:0030660) | 1/12 | 0.1136443 | 1.0000000 | 0 | 0 | 8.3333333 | 18.1223455 | GJA1 |
| 43 | cytoplasmic membrane-bounded vesicle (GO:0016023) | 8/492 | 0.1214544 | 1.0000000 | 0 | 0 | 1.6260163 | 3.4279944 | NPPC;DDC;PLA2G1B;CD207;SFTPD;SCGB1A1;SCG5;SYT13 |
| 44 | axolemma (GO:0030673) | 1/13 | 0.1225132 | 1.0000000 | 0 | 0 | 7.6923077 | 16.1502800 | ROBO2 |
| 45 | fascia adherens (GO:0005916) | 1/13 | 0.1225132 | 1.0000000 | 0 | 0 | 7.6923077 | 16.1502800 | GJA1 |
| 46 | axonal growth cone (GO:0044295) | 1/13 | 0.1225132 | 1.0000000 | 0 | 0 | 7.6923077 | 16.1502800 | GPM6A |
| 47 | external side of plasma membrane (GO:0009897) | 4/191 | 0.1251565 | 1.0000000 | 0 | 0 | 2.0942408 | 4.3522307 | SCUBE1;CD8B;FCRL6;HLA-DQB2 |
| 48 | T cell receptor complex (GO:0042101) | 1/14 | 0.1312938 | 1.0000000 | 0 | 0 | 7.1428571 | 14.5022708 | CD8B |
| 49 | gap junction (GO:0005921) | 1/15 | 0.1399869 | 1.0000000 | 0 | 0 | 6.6666667 | 13.1080425 | GJA1 |
| 50 | coated vesicle membrane (GO:0030662) | 2/66 | 0.1412394 | 1.0000000 | 0 | 0 | 3.0303030 | 5.9312088 | CD207;HLA-DQB2 |
| 51 | axon part (GO:0033267) | 3/133 | 0.1485253 | 1.0000000 | 0 | 0 | 2.2556391 | 4.3015042 | ROBO2;GPM6A;SNCG |
| 52 | neuronal postsynaptic density (GO:0097481) | 1/18 | 0.1655504 | 1.0000000 | 0 | 0 | 5.5555556 | 9.9915545 | GRIK1 |
| 53 | I band (GO:0031674) | 1/19 | 0.1739024 | 1.0000000 | 0 | 0 | 5.2631579 | 9.2066381 | MYZAP |
| 54 | anchored component of membrane (GO:0031225) | 3/150 | 0.1900320 | 1.0000000 | 0 | 0 | 2.0000000 | 3.3211257 | CD52;LYPD1;GPC3 |
| 55 | cornified envelope (GO:0001533) | 1/23 | 0.2064868 | 1.0000000 | 0 | 0 | 4.3478261 | 6.8587782 | CNFN |
| 56 | side of membrane (GO:0098552) | 4/235 | 0.2094034 | 1.0000000 | 0 | 0 | 1.7021277 | 2.6612640 | SCUBE1;CD8B;FCRL6;HLA-DQB2 |
| 57 | Golgi lumen (GO:0005796) | 2/86 | 0.2125388 | 1.0000000 | 0 | 0 | 2.3255814 | 3.6014667 | PROS1;GPC3 |
| 58 | cortical actin cytoskeleton (GO:0030864) | 1/24 | 0.2144310 | 1.0000000 | 0 | 0 | 4.1666667 | 6.4156966 | MYZAP |
| 59 | connexon complex (GO:0005922) | 1/24 | 0.2144310 | 1.0000000 | 0 | 0 | 4.1666667 | 6.4156966 | GJA1 |
| 60 | presynaptic active zone (GO:0048786) | 1/25 | 0.2222961 | 1.0000000 | 0 | 0 | 4.0000000 | 6.0149794 | PPFIA2 |
| 61 | collagen trimer (GO:0005581) | 2/91 | 0.2309240 | 1.0000000 | 0 | 0 | 2.1978022 | 3.2212458 | SFTPD;EMID1 |
| 62 | endocytic vesicle membrane (GO:0030666) | 2/94 | 0.2420055 | 1.0000000 | 0 | 0 | 2.1276596 | 3.0187127 | CD207;HLA-DQB2 |
| 63 | integral component of lumenal side of endoplasmic reticulum membrane (GO:0071556) | 1/28 | 0.2454244 | 1.0000000 | 0 | 0 | 3.5714286 | 5.0170219 | HLA-DQB2 |
| 64 | endocytic vesicle (GO:0030139) | 2/96 | 0.2494068 | 1.0000000 | 0 | 0 | 2.0833333 | 2.8930625 | SFTPD;CD207 |
| 65 | postsynaptic density (GO:0014069) | 2/98 | 0.2568151 | 1.0000000 | 0 | 0 | 2.0408163 | 2.7742832 | CAMK2N1;GRIK1 |
| 66 | ER to Golgi transport vesicle membrane (GO:0012507) | 1/30 | 0.2604618 | 1.0000000 | 0 | 0 | 3.3333333 | 4.4843302 | HLA-DQB2 |
| 67 | lysosome (GO:0005764) | 4/261 | 0.2651645 | 1.0000000 | 0 | 0 | 1.5325670 | 2.0343371 | GJA1;RAMP2;SFTPD;SLC7A14 |
| 68 | lytic vacuole (GO:0000323) | 4/261 | 0.2651645 | 1.0000000 | 0 | 0 | 1.5325670 | 2.0343371 | GJA1;RAMP2;SFTPD;SLC7A14 |
| 69 | axon terminus (GO:0043679) | 1/34 | 0.2896478 | 1.0000000 | 0 | 0 | 2.9411765 | 3.6443812 | SNCG |
| 70 | late endosome (GO:0005770) | 2/107 | 0.2901569 | 1.0000000 | 0 | 0 | 1.8691589 | 2.3127732 | GJA1;HLA-DQB2 |
| 71 | neuron projection membrane (GO:0032589) | 1/35 | 0.2967634 | 1.0000000 | 0 | 0 | 2.8571429 | 3.4709146 | ROBO2 |
| 72 | rough endoplasmic reticulum (GO:0005791) | 1/35 | 0.2967634 | 1.0000000 | 0 | 0 | 2.8571429 | 3.4709146 | SCGB1A1 |
| 73 | contractile fiber (GO:0043292) | 1/36 | 0.3038081 | 1.0000000 | 0 | 0 | 2.7777778 | 3.3093308 | GJA1 |
| 74 | intercalated disc (GO:0014704) | 1/37 | 0.3107825 | 1.0000000 | 0 | 0 | 2.7027027 | 3.1585455 | GJA1 |
| 75 | cell projection membrane (GO:0031253) | 3/196 | 0.3123712 | 1.0000000 | 0 | 0 | 1.5306122 | 1.7809638 | ROBO2;OPN1SW;CNGA1 |
| 76 | membrane raft (GO:0045121) | 3/200 | 0.3233045 | 1.0000000 | 0 | 0 | 1.5000000 | 1.6937411 | GJA1;DLC1;KCNA3 |
| 77 | apical plasma membrane (GO:0016324) | 3/201 | 0.3260385 | 1.0000000 | 0 | 0 | 1.4925373 | 1.6727460 | KISS1;GJA1;ABCG2 |
| 78 | anchored component of plasma membrane (GO:0046658) | 1/40 | 0.3312915 | 1.0000000 | 0 | 0 | 2.5000000 | 2.7618913 | GPC3 |
| 79 | vacuole (GO:0005773) | 4/293 | 0.3368702 | 1.0000000 | 0 | 0 | 1.3651877 | 1.4854027 | GJA1;RAMP2;SFTPD;SLC7A14 |
| 80 | transport vesicle membrane (GO:0030658) | 1/41 | 0.3379920 | 1.0000000 | 0 | 0 | 2.4390244 | 2.6456903 | HLA-DQB2 |
| 81 | presynaptic membrane (GO:0042734) | 1/44 | 0.3576952 | 1.0000000 | 0 | 0 | 2.2727273 | 2.3365317 | GRIK1 |
| 82 | cell-cell contact zone (GO:0044291) | 1/44 | 0.3576952 | 1.0000000 | 0 | 0 | 2.2727273 | 2.3365317 | GJA1 |
| 83 | neuron projection terminus (GO:0044306) | 1/44 | 0.3576952 | 1.0000000 | 0 | 0 | 2.2727273 | 2.3365317 | SNCG |
| 84 | lateral plasma membrane (GO:0016328) | 1/46 | 0.3705054 | 1.0000000 | 0 | 0 | 2.1739130 | 2.1584503 | GJA1 |
| 85 | cell-cell adherens junction (GO:0005913) | 1/47 | 0.3768149 | 1.0000000 | 0 | 0 | 2.1276596 | 2.0765984 | GJA1 |
| 86 | filopodium (GO:0030175) | 1/48 | 0.3830614 | 1.0000000 | 0 | 0 | 2.0833333 | 1.9990833 | GPM6A |
| 87 | platelet alpha granule lumen (GO:0031093) | 1/48 | 0.3830614 | 1.0000000 | 0 | 0 | 2.0833333 | 1.9990833 | PROS1 |
| 88 | cortical cytoskeleton (GO:0030863) | 1/50 | 0.3953682 | 1.0000000 | 0 | 0 | 2.0000000 | 1.8558758 | MYZAP |
| 89 | cytoplasmic mRNA processing body (GO:0000932) | 1/50 | 0.3953682 | 1.0000000 | 0 | 0 | 2.0000000 | 1.8558758 | APOBEC3H |
| 90 | chloride channel complex (GO:0034707) | 1/50 | 0.3953682 | 1.0000000 | 0 | 0 | 2.0000000 | 1.8558758 | GABRD |
| 91 | cytoplasmic vesicle membrane (GO:0030659) | 3/229 | 0.4021216 | 1.0000000 | 0 | 0 | 1.3100437 | 1.1934508 | GJA1;CD207;HLA-DQB2 |
| 92 | microtubule associated complex (GO:0005875) | 2/138 | 0.4023514 | 1.0000000 | 0 | 0 | 1.4492754 | 1.3194631 | DCX;KIF12 |
| 93 | early endosome (GO:0005769) | 2/141 | 0.4128121 | 1.0000000 | 0 | 0 | 1.4184397 | 1.2549827 | GJA1;HLA-DQB2 |
| 94 | kinesin complex (GO:0005871) | 1/53 | 0.4133717 | 1.0000000 | 0 | 0 | 1.8867925 | 1.6668075 | KIF12 |
| 95 | coated pit (GO:0005905) | 1/54 | 0.4192536 | 1.0000000 | 0 | 0 | 1.8518519 | 1.6097765 | RAMP2 |
| 96 | dendrite (GO:0030425) | 3/236 | 0.4208286 | 1.0000000 | 0 | 0 | 1.2711864 | 1.1002496 | CAMK2N1;GRID1;GRIK1 |
| 97 | intermediate filament cytoskeleton (GO:0045111) | 1/55 | 0.4250768 | 1.0000000 | 0 | 0 | 1.8181818 | 1.5554281 | KRT4 |
| 98 | cell-cell junction (GO:0005911) | 4/335 | 0.4316984 | 1.0000000 | 0 | 0 | 1.1940299 | 1.0030187 | GJA1;KIAA1462;SKAP1;JAM2 |
| 99 | plasma membrane raft (GO:0044853) | 1/58 | 0.4422000 | 1.0000000 | 0 | 0 | 1.7241379 | 1.4068845 | DLC1 |
| 100 | caveola (GO:0005901) | 1/58 | 0.4422000 | 1.0000000 | 0 | 0 | 1.7241379 | 1.4068845 | DLC1 |
| 101 | vesicle membrane (GO:0012506) | 3/249 | 0.4550271 | 1.0000000 | 0 | 0 | 1.2048193 | 0.9486727 | GJA1;CD207;HLA-DQB2 |
| 102 | secretory granule lumen (GO:0034774) | 1/62 | 0.4642441 | 1.0000000 | 0 | 0 | 1.6129032 | 1.2376529 | PROS1 |
| 103 | transport vesicle (GO:0030133) | 1/62 | 0.4642441 | 1.0000000 | 0 | 0 | 1.6129032 | 1.2376529 | SYT13 |
| 104 | endoplasmic reticulum membrane (GO:0005789) | 5/449 | 0.4675027 | 1.0000000 | 0 | 0 | 1.1135857 | 0.8467150 | GJA1;CYP2W1;CYP2A13;PROS1;CYP2F1 |
| 105 | sarcolemma (GO:0042383) | 1/63 | 0.4696183 | 1.0000000 | 0 | 0 | 1.5873016 | 1.1997381 | ALOX12 |
| 106 | nuclear matrix (GO:0016363) | 1/64 | 0.4749389 | 1.0000000 | 0 | 0 | 1.5625000 | 1.1633893 | RUNX1T1 |
| 107 | blood microparticle (GO:0072562) | 2/161 | 0.4800636 | 1.0000000 | 0 | 0 | 1.2422360 | 0.9115984 | IGHG4;PROS1 |
| 108 | lysosomal lumen (GO:0043202) | 1/67 | 0.4905840 | 1.0000000 | 0 | 0 | 1.4925373 | 1.0629235 | GPC3 |
| 109 | cytoplasmic vesicle part (GO:0044433) | 4/363 | 0.4930163 | 1.0000000 | 0 | 0 | 1.1019284 | 0.7792982 | GJA1;PROS1;CD207;HLA-DQB2 |
| 110 | vacuolar lumen (GO:0005775) | 1/70 | 0.5057652 | 1.0000000 | 0 | 0 | 1.4285714 | 0.9738324 | GPC3 |
| 111 | endosome membrane (GO:0010008) | 2/175 | 0.5242613 | 1.0000000 | 0 | 0 | 1.1428571 | 0.7380171 | CD8B;CD207 |
| 112 | vesicle lumen (GO:0031983) | 1/76 | 0.5347903 | 1.0000000 | 0 | 0 | 1.3157895 | 0.8235271 | PROS1 |
| 113 | cytoplasmic membrane-bounded vesicle lumen (GO:0060205) | 1/76 | 0.5347903 | 1.0000000 | 0 | 0 | 1.3157895 | 0.8235271 | PROS1 |
| 114 | vacuolar part (GO:0044437) | 3/285 | 0.5448057 | 1.0000000 | 0 | 0 | 1.0526316 | 0.6392906 | GPC3;HLA-DOA;HLA-DQB2 |
| 115 | synaptic vesicle (GO:0008021) | 1/86 | 0.5794443 | 1.0000000 | 0 | 0 | 1.1627907 | 0.6345183 | DDC |
| 116 | intermediate filament (GO:0005882) | 2/196 | 0.5856881 | 1.0000000 | 0 | 0 | 1.0204082 | 0.5458856 | GJA1;KRT4 |
| 117 | lysosomal membrane (GO:0005765) | 2/196 | 0.5856881 | 1.0000000 | 0 | 0 | 1.0204082 | 0.5458856 | HLA-DOA;HLA-DQB2 |
| 118 | endosomal part (GO:0044440) | 2/200 | 0.5967066 | 1.0000000 | 0 | 0 | 1.0000000 | 0.5163298 | CD8B;CD207 |
| 119 | Golgi membrane (GO:0000139) | 3/308 | 0.5974940 | 1.0000000 | 0 | 0 | 0.9740260 | 0.5016341 | GJA1;PROS1;HLA-DQB2 |
| 120 | integral component of endoplasmic reticulum membrane (GO:0030176) | 1/94 | 0.6120753 | 1.0000000 | 0 | 0 | 1.0638298 | 0.5222340 | HLA-DQB2 |
| 121 | leading edge membrane (GO:0031256) | 1/95 | 0.6159728 | 1.0000000 | 0 | 0 | 1.0526316 | 0.5100552 | ROBO2 |
| 122 | vacuolar membrane (GO:0005774) | 2/208 | 0.6180843 | 1.0000000 | 0 | 0 | 0.9615385 | 0.4626254 | HLA-DOA;HLA-DQB2 |
| 123 | keratin filament (GO:0045095) | 1/98 | 0.6274332 | 1.0000000 | 0 | 0 | 1.0204082 | 0.4756306 | KRT4 |
| 124 | growth cone (GO:0030426) | 1/99 | 0.6311772 | 1.0000000 | 0 | 0 | 1.0101010 | 0.4648167 | GPM6A |
| 125 | site of polarized growth (GO:0030427) | 1/102 | 0.6421861 | 1.0000000 | 0 | 0 | 0.9803922 | 0.4341933 | GPM6A |
| 126 | cell cortex part (GO:0044448) | 1/105 | 0.6528680 | 1.0000000 | 0 | 0 | 0.9523810 | 0.4060766 | MYZAP |
| 127 | ciliary part (GO:0044441) | 2/223 | 0.6558105 | 1.0000000 | 0 | 0 | 0.8968610 | 0.3783707 | OPN1SW;CNGA1 |
| 128 | occluding junction (GO:0070160) | 1/108 | 0.6632325 | 1.0000000 | 0 | 0 | 0.9259259 | 0.3802127 | JAM2 |
| 129 | tight junction (GO:0005923) | 1/108 | 0.6632325 | 1.0000000 | 0 | 0 | 0.9259259 | 0.3802127 | JAM2 |
| 130 | peroxisome (GO:0005777) | 1/109 | 0.6666184 | 1.0000000 | 0 | 0 | 0.9174312 | 0.3720527 | ACOXL |
| 131 | nuclear envelope (GO:0005635) | 1/110 | 0.6699705 | 1.0000000 | 0 | 0 | 0.9090909 | 0.3641106 | SCGB1A1 |
| 132 | ribonucleoprotein granule (GO:0035770) | 1/111 | 0.6732890 | 1.0000000 | 0 | 0 | 0.9009009 | 0.3563789 | APOBEC3H |
| 133 | cytoplasmic ribonucleoprotein granule (GO:0036464) | 1/111 | 0.6732890 | 1.0000000 | 0 | 0 | 0.9009009 | 0.3563789 | APOBEC3H |
| 134 | mitochondrial outer membrane (GO:0005741) | 1/118 | 0.6956073 | 1.0000000 | 0 | 0 | 0.8474576 | 0.3076017 | GJA1 |
| 135 | organelle envelope (GO:0031967) | 1/123 | 0.7106138 | 1.0000000 | 0 | 0 | 0.8130081 | 0.2777449 | SCGB1A1 |
| 136 | microbody (GO:0042579) | 1/123 | 0.7106138 | 1.0000000 | 0 | 0 | 0.8130081 | 0.2777449 | ACOXL |
| 137 | envelope (GO:0031975) | 1/123 | 0.7106138 | 1.0000000 | 0 | 0 | 0.8130081 | 0.2777449 | SCGB1A1 |
| 138 | organelle outer membrane (GO:0031968) | 1/131 | 0.7331076 | 1.0000000 | 0 | 0 | 0.7633588 | 0.2369945 | GJA1 |
| 139 | outer membrane (GO:0019867) | 1/137 | 0.7488283 | 1.0000000 | 0 | 0 | 0.7299270 | 0.2111281 | GJA1 |
| 140 | basolateral plasma membrane (GO:0016323) | 1/138 | 0.7513574 | 1.0000000 | 0 | 0 | 0.7246377 | 0.2071550 | SLC4A10 |
| 141 | Golgi apparatus (GO:0005794) | 7/865 | 0.7667659 | 1.0000000 | 0 | 0 | 0.8092486 | 0.2149152 | CNKSR2;GJA1;KCNJ6;ST6GAL2;DUSP26;EMID1;JAKMIP2 |
| 142 | axon (GO:0030424) | 1/161 | 0.8030171 | 1.0000000 | 0 | 0 | 0.6211180 | 0.1362604 | DDC |
| 143 | chromosome (GO:0005694) | 1/166 | 0.8127489 | 1.0000000 | 0 | 0 | 0.6024096 | 0.1248994 | MEIOB |
| 144 | contractile fiber part (GO:0044449) | 1/167 | 0.8146371 | 1.0000000 | 0 | 0 | 0.5988024 | 0.1227620 | MYZAP |
| 145 | actin cytoskeleton (GO:0015629) | 1/193 | 0.8576013 | 1.0000000 | 0 | 0 | 0.5181347 | 0.0795938 | MYOZ1 |
| 146 | focal adhesion (GO:0005925) | 2/352 | 0.8698337 | 1.0000000 | 0 | 0 | 0.5681818 | 0.0792348 | GJA1;DLC1 |
| 147 | cell-substrate adherens junction (GO:0005924) | 2/358 | 0.8759198 | 1.0000000 | 0 | 0 | 0.5586592 | 0.0740116 | GJA1;DLC1 |
| 148 | microtubule (GO:0005874) | 2/360 | 0.8778898 | 1.0000000 | 0 | 0 | 0.5555556 | 0.0723523 | DCX;KIF12 |
| 149 | cell-substrate junction (GO:0030055) | 2/362 | 0.8798311 | 1.0000000 | 0 | 0 | 0.5524862 | 0.0707322 | GJA1;DLC1 |
| 150 | integral component of organelle membrane (GO:0031301) | 1/211 | 0.8813857 | 1.0000000 | 0 | 0 | 0.4739336 | 0.0598388 | HLA-DQB2 |
| 151 | synapse (GO:0045202) | 1/243 | 0.9143243 | 1.0000000 | 0 | 0 | 0.4115226 | 0.0368601 | FRRS1L |
| 152 | cilium (GO:0005929) | 1/243 | 0.9143243 | 1.0000000 | 0 | 0 | 0.4115226 | 0.0368601 | CYS1 |
| 153 | adherens junction (GO:0005912) | 2/405 | 0.9152623 | 1.0000000 | 0 | 0 | 0.4938272 | 0.0437257 | GJA1;DLC1 |
| 154 | perinuclear region of cytoplasm (GO:0048471) | 2/411 | 0.9193490 | 1.0000000 | 0 | 0 | 0.4866180 | 0.0409195 | CX3CR1;SNCG |
| 155 | anchoring junction (GO:0070161) | 2/419 | 0.9245113 | 1.0000000 | 0 | 0 | 0.4773270 | 0.0374654 | GJA1;DLC1 |
| 156 | transcription factor complex (GO:0005667) | 1/268 | 0.9335761 | 1.0000000 | 0 | 0 | 0.3731343 | 0.0256466 | BEX1 |
| 157 | intracellular (GO:0005622) | 4/730 | 0.9369519 | 1.0000000 | 0 | 0 | 0.5479452 | 0.0356840 | SEC14L3;ZNF728;DCX;ZNF114 |
| 158 | mitochondrial membrane (GO:0031966) | 1/457 | 0.9904020 | 1.0000000 | 0 | 0 | 0.2188184 | 0.0021104 | GJA1 |
| 159 | cytosol (GO:0005829) | 15/2529 | 0.9928792 | 1.0000000 | 0 | 0 | 0.5931198 | 0.0042386 | DDC;ADH1C;STAC;ADH1B;QPRT;ALOX12;IFIT1;OASL;CH25H;GJA1;FABP3;DLC1;DCX;UBASH3A;ANXA9 |
| 160 | mitochondrion (GO:0005739) | 2/1269 | 0.9999686 | 1.0000000 | 0 | 0 | 0.1576044 | 0.0000049 | DUSP26;ABCG2 |
| 161 | nucleolus (GO:0005730) | 2/1653 | 0.9999955 | 1.0000000 | 0 | 0 | 0.1209921 | 0.0000005 | FGF18;OASL |
go_molecular %>%
knitr::kable(
format = "html", align = rep("c", ncol(go_molecular) + 1),
row.names = TRUE
) %>%
kableExtra::kable_styling() %>%
kableExtra::scroll_box(height = "300px")
| Term | Overlap | P.value | Adjusted.P.value | Old.P.value | Old.Adjusted.P.value | Odds.Ratio | Combined.Score | Genes | |
|---|---|---|---|---|---|---|---|---|---|
| 1 | voltage-gated potassium channel activity (GO:0005249) | 6/86 | 0.0002244 | 0.2549732 | 0 | 0 | 6.9767442 | 58.6176657 | KCNJ6;CNGA1;KCNA3;KCNA4;KCNJ1;KCNK3 |
| 2 | potassium channel activity (GO:0005267) | 6/118 | 0.0012087 | 0.6865446 | 0 | 0 | 5.0847458 | 34.1603669 | KCNJ6;CNGA1;KCNA3;KCNA4;KCNJ1;KCNK3 |
| 3 | channel activity (GO:0015267) | 12/427 | 0.0012766 | 0.4834037 | 0 | 0 | 2.8103044 | 18.7266307 | GPM6A;GJA1;KCNJ6;GRID1;KCNA3;CNGA1;KCNA4;GRIK1;GABRD;KCNJ1;CLCA4;KCNK3 |
| 4 | passive transmembrane transporter activity (GO:0022803) | 12/427 | 0.0012766 | 0.3625528 | 0 | 0 | 2.8103044 | 18.7266307 | GPM6A;GJA1;KCNJ6;GRID1;KCNA3;CNGA1;KCNA4;GRIK1;GABRD;KCNJ1;CLCA4;KCNK3 |
| 5 | iron ion binding (GO:0005506) | 7/172 | 0.0017549 | 0.3987215 | 0 | 0 | 4.0697674 | 25.8239879 | CH25H;CYP2W1;CYP2A13;P4HA3;ALOX12;CYP4F22;CYP2F1 |
| 6 | ion channel activity (GO:0005216) | 11/396 | 0.0022098 | 0.4183888 | 0 | 0 | 2.7777778 | 16.9857035 | GPM6A;KCNJ6;GRID1;KCNA3;CNGA1;KCNA4;GRIK1;GABRD;KCNJ1;CLCA4;KCNK3 |
| 7 | potassium ion transmembrane transporter activity (GO:0015079) | 6/138 | 0.0026751 | 0.4341297 | 0 | 0 | 4.3478261 | 25.7555234 | KCNJ6;CNGA1;KCNA3;KCNA4;KCNJ1;KCNK3 |
| 8 | substrate-specific channel activity (GO:0022838) | 11/406 | 0.0026774 | 0.3801896 | 0 | 0 | 2.7093596 | 16.0472995 | GPM6A;KCNJ6;GRID1;KCNA3;CNGA1;KCNA4;GRIK1;GABRD;KCNJ1;CLCA4;KCNK3 |
| 9 | alcohol dehydrogenase (NAD) activity (GO:0004022) | 2/8 | 0.0026778 | 0.3379938 | 0 | 0 | 25.0000000 | 148.0692967 | ADH1C;ADH1B |
| 10 | cytidine deaminase activity (GO:0004126) | 2/8 | 0.0026778 | 0.3041944 | 0 | 0 | 25.0000000 | 148.0692967 | APOBEC2;APOBEC3H |
| 11 | monooxygenase activity (GO:0004497) | 5/99 | 0.0031830 | 0.3287152 | 0 | 0 | 5.0505051 | 29.0400857 | CH25H;CYP2W1;CYP2A13;CYP4F22;CYP2F1 |
| 12 | ligand-gated ion channel activity (GO:0015276) | 6/145 | 0.0034178 | 0.3235552 | 0 | 0 | 4.1379310 | 23.4982656 | KCNJ6;GRID1;CNGA1;GRIK1;KCNJ1;GABRD |
| 13 | ligand-gated channel activity (GO:0022834) | 6/145 | 0.0034178 | 0.2986663 | 0 | 0 | 4.1379310 | 23.4982656 | KCNJ6;GRID1;CNGA1;GRIK1;KCNJ1;GABRD |
| 14 | voltage-gated cation channel activity (GO:0022843) | 6/149 | 0.0039058 | 0.3169247 | 0 | 0 | 4.0268456 | 22.3300765 | KCNJ6;CNGA1;KCNA3;KCNA4;KCNJ1;KCNK3 |
| 15 | MHC class II receptor activity (GO:0032395) | 2/11 | 0.0051570 | 0.3905584 | 0 | 0 | 18.1818182 | 95.7708415 | HLA-DOA;HLA-DQB2 |
| 16 | gated channel activity (GO:0022836) | 9/323 | 0.0053542 | 0.3801493 | 0 | 0 | 2.7863777 | 14.5723959 | KCNJ6;GRID1;KCNA3;CNGA1;KCNA4;GRIK1;GABRD;KCNJ1;KCNK3 |
| 17 | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen (GO:0016705) | 6/163 | 0.0060252 | 0.4026243 | 0 | 0 | 3.6809816 | 18.8164667 | CH25H;CYP2W1;CYP2A13;P4HA3;CYP4F22;CYP2F1 |
| 18 | voltage-gated channel activity (GO:0022832) | 6/189 | 0.0120086 | 0.7578743 | 0 | 0 | 3.1746032 | 14.0385224 | KCNJ6;CNGA1;KCNA3;KCNA4;KCNJ1;KCNK3 |
| 19 | voltage-gated ion channel activity (GO:0005244) | 6/189 | 0.0120086 | 0.7179862 | 0 | 0 | 3.1746032 | 14.0385224 | KCNJ6;CNGA1;KCNA3;KCNA4;KCNJ1;KCNK3 |
| 20 | extracellular-glutamate-gated ion channel activity (GO:0005234) | 2/18 | 0.0137022 | 0.7782852 | 0 | 0 | 11.1111111 | 47.6688727 | GRID1;GRIK1 |
| 21 | ionotropic glutamate receptor activity (GO:0004970) | 2/19 | 0.0152144 | 0.8230292 | 0 | 0 | 10.5263158 | 44.0579974 | GRID1;GRIK1 |
| 22 | aromatase activity (GO:0070330) | 2/21 | 0.0184420 | 0.9522790 | 0 | 0 | 9.5238095 | 38.0297462 | CYP2A13;CYP2F1 |
| 23 | metal ion transmembrane transporter activity (GO:0046873) | 9/400 | 0.0196012 | 0.9681294 | 0 | 0 | 2.2500000 | 8.8473688 | SLC5A7;GPM6A;KCNJ6;SLC6A13;KCNA3;CNGA1;KCNA4;KCNJ1;KCNK3 |
| 24 | GABA receptor activity (GO:0016917) | 2/22 | 0.0201544 | 0.9539738 | 0 | 0 | 9.0909091 | 35.4939443 | GABBR2;GABRD |
| 25 | inward rectifier potassium channel activity (GO:0005242) | 2/22 | 0.0201544 | 0.9158148 | 0 | 0 | 9.0909091 | 35.4939443 | KCNJ6;KCNJ1 |
| 26 | monovalent inorganic cation transmembrane transporter activity (GO:0015077) | 8/343 | 0.0224125 | 0.9792545 | 0 | 0 | 2.3323615 | 8.8586258 | SLC5A7;KCNJ6;SLC6A13;KCNA3;CNGA1;KCNA4;KCNJ1;KCNK3 |
| 27 | fibroblast growth factor receptor binding (GO:0005104) | 2/24 | 0.0237689 | 1.0000000 | 0 | 0 | 8.3333333 | 31.1614659 | FGF9;FGF18 |
| 28 | cation channel activity (GO:0005261) | 7/285 | 0.0248727 | 1.0000000 | 0 | 0 | 2.4561404 | 9.0729396 | GPM6A;KCNJ6;KCNA3;CNGA1;KCNA4;KCNJ1;KCNK3 |
| 29 | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen (GO:0016712) | 2/25 | 0.0256683 | 1.0000000 | 0 | 0 | 8.0000000 | 29.2999902 | CYP2A13;CYP2F1 |
| 30 | oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen (GO:0016702) | 2/25 | 0.0256683 | 0.9719727 | 0 | 0 | 8.0000000 | 29.2999902 | P4HA3;ALOX12 |
| 31 | oxidoreductase activity, acting on single donors with incorporation of molecular oxygen (GO:0016701) | 2/26 | 0.0276272 | 1.0000000 | 0 | 0 | 7.6923077 | 27.6073469 | P4HA3;ALOX12 |
| 32 | amino acid transmembrane transporter activity (GO:0015171) | 3/66 | 0.0284510 | 1.0000000 | 0 | 0 | 4.5454545 | 16.1798713 | SLC7A14;SLC6A13;SLC38A4 |
| 33 | glutamate receptor activity (GO:0008066) | 2/27 | 0.0296442 | 1.0000000 | 0 | 0 | 7.4074074 | 26.0628716 | GRID1;GRIK1 |
| 34 | coreceptor activity (GO:0015026) | 2/27 | 0.0296442 | 0.9904662 | 0 | 0 | 7.4074074 | 26.0628716 | RAMP2;CD8B |
| 35 | deaminase activity (GO:0019239) | 2/29 | 0.0338475 | 1.0000000 | 0 | 0 | 6.8965517 | 23.3509763 | APOBEC2;APOBEC3H |
| 36 | anion transmembrane transporter activity (GO:0008509) | 6/245 | 0.0369668 | 1.0000000 | 0 | 0 | 2.4489796 | 8.0760842 | SLC6A13;SLC7A14;SLC4A10;GABRD;CLCA4;SLC38A4 |
| 37 | extracellular ligand-gated ion channel activity (GO:0005230) | 3/74 | 0.0380556 | 1.0000000 | 0 | 0 | 4.0540541 | 13.2515162 | GRID1;GRIK1;GABRD |
| 38 | SH2 domain binding (GO:0042169) | 2/31 | 0.0382674 | 1.0000000 | 0 | 0 | 6.4516129 | 21.0526212 | DLC1;SKAP1 |
| 39 | symporter activity (GO:0015293) | 4/130 | 0.0416931 | 1.0000000 | 0 | 0 | 3.0769231 | 9.7766739 | SLC5A7;SLC6A13;SLC4A10;SLC38A4 |
| 40 | beta-tubulin binding (GO:0048487) | 2/35 | 0.0477172 | 1.0000000 | 0 | 0 | 5.7142857 | 17.3855107 | GJA1;SNCG |
| 41 | heme binding (GO:0020037) | 4/137 | 0.0488995 | 1.0000000 | 0 | 0 | 2.9197080 | 8.8116443 | CYP2W1;CYP2A13;CYP4F22;CYP2F1 |
| 42 | RNA polymerase II activating transcription factor binding (GO:0001102) | 2/36 | 0.0501995 | 1.0000000 | 0 | 0 | 5.5555556 | 16.6208344 | BEX1;DUSP26 |
| 43 | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines (GO:0016814) | 2/36 | 0.0501995 | 1.0000000 | 0 | 0 | 5.5555556 | 16.6208344 | APOBEC2;APOBEC3H |
| 44 | delayed rectifier potassium channel activity (GO:0005251) | 2/36 | 0.0501995 | 1.0000000 | 0 | 0 | 5.5555556 | 16.6208344 | KCNA3;KCNA4 |
| 45 | carboxylic acid binding (GO:0031406) | 5/200 | 0.0508440 | 1.0000000 | 0 | 0 | 2.5000000 | 7.4474830 | FABP3;DDC;PLA2G1B;P4HA3;ANXA9 |
| 46 | organic acid binding (GO:0043177) | 5/201 | 0.0517369 | 1.0000000 | 0 | 0 | 2.4875622 | 7.3671242 | FABP3;DDC;PLA2G1B;P4HA3;ANXA9 |
| 47 | heparin binding (GO:0008201) | 4/140 | 0.0521854 | 1.0000000 | 0 | 0 | 2.8571429 | 8.4370074 | SMOC2;ECM2;FGF9;PCOLCE2 |
| 48 | sulfur compound binding (GO:1901681) | 5/206 | 0.0563388 | 1.0000000 | 0 | 0 | 2.4271845 | 6.9814843 | SMOC2;ECM2;FGF9;PCOLCE2;GPC3 |
| 49 | tetrapyrrole binding (GO:0046906) | 4/146 | 0.0591100 | 1.0000000 | 0 | 0 | 2.7397260 | 7.7489166 | CYP2W1;CYP2A13;CYP4F22;CYP2F1 |
| 50 | inorganic cation transmembrane transporter activity (GO:0022890) | 9/497 | 0.0627487 | 1.0000000 | 0 | 0 | 1.8108652 | 5.0135933 | SLC5A7;GPM6A;KCNJ6;SLC6A13;KCNA3;CNGA1;KCNA4;KCNJ1;KCNK3 |
| 51 | protein phosphatase binding (GO:0019903) | 3/94 | 0.0682467 | 1.0000000 | 0 | 0 | 3.1914894 | 8.5679557 | FCRL6;FLT4;SKAP1 |
| 52 | axon guidance receptor activity (GO:0008046) | 1/8 | 0.0772681 | 1.0000000 | 0 | 0 | 12.5000000 | 32.0059307 | ROBO2 |
| 53 | intracellular cAMP activated cation channel activity (GO:0005222) | 1/8 | 0.0772681 | 1.0000000 | 0 | 0 | 12.5000000 | 32.0059307 | CNGA1 |
| 54 | heme transporter activity (GO:0015232) | 1/8 | 0.0772681 | 1.0000000 | 0 | 0 | 12.5000000 | 32.0059307 | ABCG2 |
| 55 | carboxylic acid transmembrane transporter activity (GO:0046943) | 3/101 | 0.0807525 | 1.0000000 | 0 | 0 | 2.9702970 | 7.4743550 | SLC6A13;SLC7A14;SLC38A4 |
| 56 | excitatory extracellular ligand-gated ion channel activity (GO:0005231) | 2/48 | 0.0832284 | 1.0000000 | 0 | 0 | 4.1666667 | 10.3590263 | GRID1;GRIK1 |
| 57 | organic acid transmembrane transporter activity (GO:0005342) | 3/104 | 0.0863951 | 1.0000000 | 0 | 0 | 2.8846154 | 7.0639147 | SLC6A13;SLC7A14;SLC38A4 |
| 58 | potassium ion binding (GO:0030955) | 1/9 | 0.0864991 | 1.0000000 | 0 | 0 | 11.1111111 | 27.1957962 | KCNA4 |
| 59 | phospholipase activator activity (GO:0016004) | 1/9 | 0.0864991 | 1.0000000 | 0 | 0 | 11.1111111 | 27.1957962 | CCL5 |
| 60 | calcium-dependent phospholipase A2 activity (GO:0047498) | 1/9 | 0.0864991 | 1.0000000 | 0 | 0 | 11.1111111 | 27.1957962 | PLA2G1B |
| 61 | fatty acid transporter activity (GO:0015245) | 1/9 | 0.0864991 | 1.0000000 | 0 | 0 | 11.1111111 | 27.1957962 | FABP3 |
| 62 | peptidyl-proline 4-dioxygenase activity (GO:0031545) | 1/9 | 0.0864991 | 1.0000000 | 0 | 0 | 11.1111111 | 27.1957962 | P4HA3 |
| 63 | protein-glutamine gamma-glutamyltransferase activity (GO:0003810) | 1/9 | 0.0864991 | 1.0000000 | 0 | 0 | 11.1111111 | 27.1957962 | TGM3 |
| 64 | opioid receptor activity (GO:0004985) | 1/9 | 0.0864991 | 1.0000000 | 0 | 0 | 11.1111111 | 27.1957962 | NPBWR1 |
| 65 | serine-type endopeptidase activity (GO:0004252) | 4/167 | 0.0869547 | 1.0000000 | 0 | 0 | 2.3952096 | 5.8499844 | TMPRSS11A;PRSS27;TMPRSS11E;TMPRSS11F |
| 66 | solute:sodium symporter activity (GO:0015370) | 2/50 | 0.0892415 | 1.0000000 | 0 | 0 | 4.0000000 | 9.6656385 | SLC5A7;SLC6A13 |
| 67 | calcium ion binding (GO:0005509) | 11/698 | 0.0922616 | 1.0000000 | 0 | 0 | 1.5759312 | 3.7556440 | SMOC2;SCUBE1;PLA2G1B;PROS1;PADI3;SPARCL1;ANXA9;TGM3;LRP1B;CDH7;FBN1 |
| 68 | tubulin binding (GO:0015631) | 5/241 | 0.0948925 | 1.0000000 | 0 | 0 | 2.0746888 | 4.8859139 | GJA1;DCX;SNCG;KIF12;JAKMIP2 |
| 69 | sodium:amino acid symporter activity (GO:0005283) | 1/10 | 0.0956382 | 1.0000000 | 0 | 0 | 10.0000000 | 23.4718325 | SLC6A13 |
| 70 | oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor (GO:0016634) | 1/10 | 0.0956382 | 1.0000000 | 0 | 0 | 10.0000000 | 23.4718325 | ACOXL |
| 71 | low-density lipoprotein receptor activity (GO:0005041) | 1/10 | 0.0956382 | 1.0000000 | 0 | 0 | 10.0000000 | 23.4718325 | LRP1B |
| 72 | hydrolase activity, acting on ether bonds (GO:0016801) | 1/10 | 0.0956382 | 1.0000000 | 0 | 0 | 10.0000000 | 23.4718325 | ALOX12 |
| 73 | activating transcription factor binding (GO:0033613) | 2/53 | 0.0984918 | 1.0000000 | 0 | 0 | 3.7735849 | 8.7463472 | BEX1;DUSP26 |
| 74 | cyclic nucleotide-gated ion channel activity (GO:0043855) | 1/11 | 0.1046863 | 1.0000000 | 0 | 0 | 9.0909091 | 20.5162457 | CNGA1 |
| 75 | receptor antagonist activity (GO:0048019) | 1/11 | 0.1046863 | 1.0000000 | 0 | 0 | 9.0909091 | 20.5162457 | CCL5 |
| 76 | outward rectifier potassium channel activity (GO:0015271) | 1/11 | 0.1046863 | 1.0000000 | 0 | 0 | 9.0909091 | 20.5162457 | KCNA3 |
| 77 | alcohol transmembrane transporter activity (GO:0015665) | 1/11 | 0.1046863 | 1.0000000 | 0 | 0 | 9.0909091 | 20.5162457 | SLC5A7 |
| 78 | toxic substance binding (GO:0015643) | 1/11 | 0.1046863 | 1.0000000 | 0 | 0 | 9.0909091 | 20.5162457 | HLA-DQB2 |
| 79 | lipase activator activity (GO:0060229) | 1/11 | 0.1046863 | 1.0000000 | 0 | 0 | 9.0909091 | 20.5162457 | CCL5 |
| 80 | intracellular cyclic nucleotide activated cation channel activity (GO:0005221) | 1/11 | 0.1046863 | 1.0000000 | 0 | 0 | 9.0909091 | 20.5162457 | CNGA1 |
| 81 | S100 protein binding (GO:0044548) | 1/11 | 0.1046863 | 1.0000000 | 0 | 0 | 9.0909091 | 20.5162457 | KCNK3 |
| 82 | long-chain fatty acid binding (GO:0036041) | 1/11 | 0.1046863 | 1.0000000 | 0 | 0 | 9.0909091 | 20.5162457 | FABP3 |
| 83 | p53 binding (GO:0002039) | 2/56 | 0.1079976 | 1.0000000 | 0 | 0 | 3.5714286 | 7.9487379 | ZNF385B;DUSP26 |
| 84 | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines (GO:0016813) | 1/12 | 0.1136443 | 1.0000000 | 0 | 0 | 8.3333333 | 18.1223455 | PADI3 |
| 85 | cation:amino acid symporter activity (GO:0005416) | 1/12 | 0.1136443 | 1.0000000 | 0 | 0 | 8.3333333 | 18.1223455 | SLC6A13 |
| 86 | receptor inhibitor activity (GO:0030547) | 1/12 | 0.1136443 | 1.0000000 | 0 | 0 | 8.3333333 | 18.1223455 | CCL5 |
| 87 | gap junction channel activity (GO:0005243) | 1/12 | 0.1136443 | 1.0000000 | 0 | 0 | 8.3333333 | 18.1223455 | GJA1 |
| 88 | monocarboxylic acid binding (GO:0033293) | 2/59 | 0.1177356 | 1.0000000 | 0 | 0 | 3.3898305 | 7.2519111 | FABP3;PLA2G1B |
| 89 | serine-type peptidase activity (GO:0008236) | 4/188 | 0.1200394 | 1.0000000 | 0 | 0 | 2.1276596 | 4.5105013 | TMPRSS11A;PRSS27;TMPRSS11E;TMPRSS11F |
| 90 | G-protein coupled peptide receptor activity (GO:0008528) | 3/121 | 0.1212860 | 1.0000000 | 0 | 0 | 2.4793388 | 5.2304234 | MC4R;CX3CR1;NPBWR1 |
| 91 | enzyme inhibitor activity (GO:0004857) | 6/336 | 0.1216895 | 1.0000000 | 0 | 0 | 1.7857143 | 3.7612194 | CAMK2N1;PROS1;SCGB1A1;GPC3;SCG5;A2ML1 |
| 92 | MHC class I protein binding (GO:0042288) | 1/13 | 0.1225132 | 1.0000000 | 0 | 0 | 7.6923077 | 16.1502800 | CD8B |
| 93 | alkali metal ion binding (GO:0031420) | 1/13 | 0.1225132 | 1.0000000 | 0 | 0 | 7.6923077 | 16.1502800 | KCNA4 |
| 94 | exodeoxyribonuclease activity, producing 5’-phosphomonoesters (GO:0016895) | 1/13 | 0.1225132 | 1.0000000 | 0 | 0 | 7.6923077 | 16.1502800 | MEIOB |
| 95 | phospholipase inhibitor activity (GO:0004859) | 1/13 | 0.1225132 | 1.0000000 | 0 | 0 | 7.6923077 | 16.1502800 | SCGB1A1 |
| 96 | exodeoxyribonuclease activity (GO:0004529) | 1/13 | 0.1225132 | 1.0000000 | 0 | 0 | 7.6923077 | 16.1502800 | MEIOB |
| 97 | peptidyl-proline dioxygenase activity (GO:0031543) | 1/13 | 0.1225132 | 1.0000000 | 0 | 0 | 7.6923077 | 16.1502800 | P4HA3 |
| 98 | inorganic anion exchanger activity (GO:0005452) | 1/13 | 0.1225132 | 1.0000000 | 0 | 0 | 7.6923077 | 16.1502800 | SLC4A10 |
| 99 | glycosaminoglycan binding (GO:0005539) | 4/190 | 0.1234406 | 1.0000000 | 0 | 0 | 2.1052632 | 4.4042012 | SMOC2;ECM2;FGF9;PCOLCE2 |
| 100 | secondary active transmembrane transporter activity (GO:0015291) | 4/191 | 0.1251565 | 1.0000000 | 0 | 0 | 2.0942408 | 4.3522307 | SLC5A7;SLC6A13;SLC4A10;SLC38A4 |
| 101 | serine hydrolase activity (GO:0017171) | 4/191 | 0.1251565 | 1.0000000 | 0 | 0 | 2.0942408 | 4.3522307 | TMPRSS11A;PRSS27;TMPRSS11E;TMPRSS11F |
| 102 | peptide receptor activity (GO:0001653) | 3/123 | 0.1256888 | 1.0000000 | 0 | 0 | 2.4390244 | 5.0584047 | MC4R;CX3CR1;NPBWR1 |
| 103 | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds (GO:0016810) | 3/123 | 0.1256888 | 1.0000000 | 0 | 0 | 2.4390244 | 5.0584047 | APOBEC2;APOBEC3H;PADI3 |
| 104 | collagen binding (GO:0005518) | 2/62 | 0.1276839 | 1.0000000 | 0 | 0 | 3.2258065 | 6.6393466 | ECM2;PCOLCE2 |
| 105 | lipoprotein particle receptor activity (GO:0030228) | 1/14 | 0.1312938 | 1.0000000 | 0 | 0 | 7.1428571 | 14.5022708 | LRP1B |
| 106 | protein tyrosine kinase activator activity (GO:0030296) | 1/14 | 0.1312938 | 1.0000000 | 0 | 0 | 7.1428571 | 14.5022708 | CCL5 |
| 107 | acyl-CoA dehydrogenase activity (GO:0003995) | 1/15 | 0.1399869 | 1.0000000 | 0 | 0 | 6.6666667 | 13.1080425 | ACOXL |
| 108 | monosaccharide binding (GO:0048029) | 2/66 | 0.1412394 | 1.0000000 | 0 | 0 | 3.0303030 | 5.9312088 | P4HA3;CD207 |
| 109 | organic anion transmembrane transporter activity (GO:0008514) | 3/130 | 0.1415370 | 1.0000000 | 0 | 0 | 2.3076923 | 4.5119861 | SLC6A13;SLC7A14;SLC38A4 |
| 110 | oxidoreductase activity, acting on CH-OH group of donors (GO:0016614) | 3/131 | 0.1438539 | 1.0000000 | 0 | 0 | 2.2900763 | 4.4403596 | ADH1C;ADH1B;HHIP |
| 111 | carbohydrate binding (GO:0030246) | 5/278 | 0.1469365 | 1.0000000 | 0 | 0 | 1.7985612 | 3.4491988 | KLRK1;P4HA3;CD207;SFTPD;CLEC4F |
| 112 | Rac GTPase activator activity (GO:0030675) | 1/16 | 0.1485935 | 1.0000000 | 0 | 0 | 6.2500000 | 11.9158813 | DLC1 |
| 113 | MHC protein complex binding (GO:0023023) | 1/16 | 0.1485935 | 1.0000000 | 0 | 0 | 6.2500000 | 11.9158813 | HLA-DOA |
| 114 | steroid hydroxylase activity (GO:0008395) | 1/16 | 0.1485935 | 1.0000000 | 0 | 0 | 6.2500000 | 11.9158813 | CH25H |
| 115 | MHC class II protein complex binding (GO:0023026) | 1/16 | 0.1485935 | 1.0000000 | 0 | 0 | 6.2500000 | 11.9158813 | HLA-DOA |
| 116 | quinone binding (GO:0048038) | 1/16 | 0.1485935 | 1.0000000 | 0 | 0 | 6.2500000 | 11.9158813 | HHIP |
| 117 | drug transmembrane transporter activity (GO:0015238) | 1/16 | 0.1485935 | 1.0000000 | 0 | 0 | 6.2500000 | 11.9158813 | ABCG2 |
| 118 | photoreceptor activity (GO:0009881) | 1/16 | 0.1485935 | 1.0000000 | 0 | 0 | 6.2500000 | 11.9158813 | OPN1SW |
| 119 | phosphatase binding (GO:0019902) | 3/136 | 0.1556231 | 1.0000000 | 0 | 0 | 2.2058824 | 4.1036430 | FCRL6;FLT4;SKAP1 |
| 120 | cGMP binding (GO:0030553) | 1/17 | 0.1571144 | 1.0000000 | 0 | 0 | 5.8823529 | 10.8869493 | CNGA1 |
| 121 | heparan sulfate proteoglycan binding (GO:0043395) | 1/17 | 0.1571144 | 1.0000000 | 0 | 0 | 5.8823529 | 10.8869493 | GPC3 |
| 122 | peptide hormone receptor binding (GO:0051428) | 1/17 | 0.1571144 | 1.0000000 | 0 | 0 | 5.8823529 | 10.8869493 | NPPC |
| 123 | CCR chemokine receptor binding (GO:0048020) | 1/17 | 0.1571144 | 1.0000000 | 0 | 0 | 5.8823529 | 10.8869493 | CCL5 |
| 124 | peptidase regulator activity (GO:0061134) | 4/209 | 0.1576916 | 1.0000000 | 0 | 0 | 1.9138756 | 3.5351465 | PCOLCE2;PROS1;GPC3;A2ML1 |
| 125 | chloride channel activity (GO:0005254) | 2/72 | 0.1621027 | 1.0000000 | 0 | 0 | 2.7777778 | 5.0542366 | GABRD;CLCA4 |
| 126 | lipase inhibitor activity (GO:0055102) | 1/18 | 0.1655504 | 1.0000000 | 0 | 0 | 5.5555556 | 9.9915545 | SCGB1A1 |
| 127 | acetylcholine receptor activity (GO:0015464) | 1/18 | 0.1655504 | 1.0000000 | 0 | 0 | 5.5555556 | 9.9915545 | ANXA9 |
| 128 | lipopolysaccharide binding (GO:0001530) | 1/18 | 0.1655504 | 1.0000000 | 0 | 0 | 5.5555556 | 9.9915545 | BPI |
| 129 | mannose binding (GO:0005537) | 1/18 | 0.1655504 | 1.0000000 | 0 | 0 | 5.5555556 | 9.9915545 | CD207 |
| 130 | neurotransmitter receptor activity (GO:0030594) | 2/74 | 0.1691769 | 1.0000000 | 0 | 0 | 2.7027027 | 4.8021906 | NPBWR1;ANXA9 |
| 131 | GABA-A receptor activity (GO:0004890) | 1/19 | 0.1739024 | 1.0000000 | 0 | 0 | 5.2631579 | 9.2066381 | GABRD |
| 132 | neurotransmitter:sodium symporter activity (GO:0005328) | 1/19 | 0.1739024 | 1.0000000 | 0 | 0 | 5.2631579 | 9.2066381 | SLC6A13 |
| 133 | cofactor transporter activity (GO:0051184) | 1/19 | 0.1739024 | 1.0000000 | 0 | 0 | 5.2631579 | 9.2066381 | ABCG2 |
| 134 | drug transporter activity (GO:0090484) | 1/20 | 0.1821712 | 1.0000000 | 0 | 0 | 5.0000000 | 8.5140422 | ABCG2 |
| 135 | sialyltransferase activity (GO:0008373) | 1/20 | 0.1821712 | 1.0000000 | 0 | 0 | 5.0000000 | 8.5140422 | ST6GAL2 |
| 136 | L-ascorbic acid binding (GO:0031418) | 1/21 | 0.1903576 | 1.0000000 | 0 | 0 | 4.7619048 | 7.8992886 | P4HA3 |
| 137 | anion channel activity (GO:0005253) | 2/80 | 0.1906887 | 1.0000000 | 0 | 0 | 2.5000000 | 4.1427819 | GABRD;CLCA4 |
| 138 | active transmembrane transporter activity (GO:0022804) | 5/307 | 0.1945656 | 1.0000000 | 0 | 0 | 1.6286645 | 2.6661005 | SLC5A7;SLC6A13;SLC4A10;ABCG2;SLC38A4 |
| 139 | solute:cation symporter activity (GO:0015294) | 2/82 | 0.1979403 | 1.0000000 | 0 | 0 | 2.4390244 | 3.9507064 | SLC5A7;SLC6A13 |
| 140 | chemoattractant activity (GO:0042056) | 1/22 | 0.1984626 | 1.0000000 | 0 | 0 | 4.5454545 | 7.3507034 | CCL5 |
| 141 | phosphatidylserine binding (GO:0001786) | 1/23 | 0.2064868 | 1.0000000 | 0 | 0 | 4.3478261 | 6.8587782 | ANXA9 |
| 142 | wide pore channel activity (GO:0022829) | 1/23 | 0.2064868 | 1.0000000 | 0 | 0 | 4.3478261 | 6.8587782 | GJA1 |
| 143 | cytokine receptor activity (GO:0004896) | 2/85 | 0.2088786 | 1.0000000 | 0 | 0 | 2.3529412 | 3.6847110 | CX3CR1;LEPR |
| 144 | chloride transmembrane transporter activity (GO:0015108) | 2/86 | 0.2125388 | 1.0000000 | 0 | 0 | 2.3255814 | 3.6014667 | GABRD;CLCA4 |
| 145 | neurotransmitter transporter activity (GO:0005326) | 1/24 | 0.2144310 | 1.0000000 | 0 | 0 | 4.1666667 | 6.4156966 | SLC6A13 |
| 146 | anion:anion antiporter activity (GO:0015301) | 1/24 | 0.2144310 | 1.0000000 | 0 | 0 | 4.1666667 | 6.4156966 | SLC4A10 |
| 147 | adenylyltransferase activity (GO:0070566) | 1/24 | 0.2144310 | 1.0000000 | 0 | 0 | 4.1666667 | 6.4156966 | OASL |
| 148 | transferase activity, transferring amino-acyl groups (GO:0016755) | 1/24 | 0.2144310 | 1.0000000 | 0 | 0 | 4.1666667 | 6.4156966 | TGM3 |
| 149 | intracellular ligand-gated ion channel activity (GO:0005217) | 1/24 | 0.2144310 | 1.0000000 | 0 | 0 | 4.1666667 | 6.4156966 | CNGA1 |
| 150 | dioxygenase activity (GO:0051213) | 2/87 | 0.2162053 | 1.0000000 | 0 | 0 | 2.2988506 | 3.5207517 | P4HA3;ALOX12 |
| 151 | phospholipase activity (GO:0004620) | 2/90 | 0.2272373 | 1.0000000 | 0 | 0 | 2.2222222 | 3.2928009 | PLA2G1B;CCL5 |
| 152 | RNA polymerase II transcription factor binding (GO:0001085) | 2/90 | 0.2272373 | 1.0000000 | 0 | 0 | 2.2222222 | 3.2928009 | BEX1;DUSP26 |
| 153 | G-protein coupled chemoattractant receptor activity (GO:0001637) | 1/26 | 0.2300829 | 1.0000000 | 0 | 0 | 3.8461538 | 5.6512139 | CX3CR1 |
| 154 | chemokine receptor activity (GO:0004950) | 1/26 | 0.2300829 | 1.0000000 | 0 | 0 | 3.8461538 | 5.6512139 | CX3CR1 |
| 155 | fatty acid binding (GO:0005504) | 1/26 | 0.2300829 | 1.0000000 | 0 | 0 | 3.8461538 | 5.6512139 | FABP3 |
| 156 | neuropeptide receptor binding (GO:0071855) | 1/26 | 0.2300829 | 1.0000000 | 0 | 0 | 3.8461538 | 5.6512139 | KISS1 |
| 157 | MHC protein binding (GO:0042287) | 1/27 | 0.2377921 | 1.0000000 | 0 | 0 | 3.7037037 | 5.3198467 | CD8B |
| 158 | thyroid hormone receptor binding (GO:0046966) | 1/27 | 0.2377921 | 1.0000000 | 0 | 0 | 3.7037037 | 5.3198467 | OASL |
| 159 | proteoglycan binding (GO:0043394) | 1/27 | 0.2377921 | 1.0000000 | 0 | 0 | 3.7037037 | 5.3198467 | GPC3 |
| 160 | microtubule binding (GO:0008017) | 3/171 | 0.2446846 | 1.0000000 | 0 | 0 | 1.7543860 | 2.4697984 | DCX;KIF12;JAKMIP2 |
| 161 | phosphatidylinositol phospholipase C activity (GO:0004435) | 1/28 | 0.2454244 | 1.0000000 | 0 | 0 | 3.5714286 | 5.0170219 | CCL5 |
| 162 | organic acid:sodium symporter activity (GO:0005343) | 1/28 | 0.2454244 | 1.0000000 | 0 | 0 | 3.5714286 | 5.0170219 | SLC6A13 |
| 163 | alpha-tubulin binding (GO:0043014) | 1/28 | 0.2454244 | 1.0000000 | 0 | 0 | 3.5714286 | 5.0170219 | SNCG |
| 164 | peptidase inhibitor activity (GO:0030414) | 3/173 | 0.2500255 | 1.0000000 | 0 | 0 | 1.7341040 | 2.4038017 | PROS1;GPC3;A2ML1 |
| 165 | phospholipase A2 activity (GO:0004623) | 1/29 | 0.2529808 | 1.0000000 | 0 | 0 | 3.4482759 | 4.7394545 | PLA2G1B |
| 166 | phospholipase C activity (GO:0004629) | 1/30 | 0.2604618 | 1.0000000 | 0 | 0 | 3.3333333 | 4.4843302 | CCL5 |
| 167 | monocarboxylic acid transmembrane transporter activity (GO:0008028) | 1/30 | 0.2604618 | 1.0000000 | 0 | 0 | 3.3333333 | 4.4843302 | SLC6A13 |
| 168 | quaternary ammonium group binding (GO:0050997) | 1/31 | 0.2678683 | 1.0000000 | 0 | 0 | 3.2258065 | 4.2492255 | SLC5A7 |
| 169 | insulin receptor binding (GO:0005158) | 1/32 | 0.2752010 | 1.0000000 | 0 | 0 | 3.1250000 | 4.0320428 | DOK5 |
| 170 | organic hydroxy compound transmembrane transporter activity (GO:1901618) | 1/32 | 0.2752010 | 1.0000000 | 0 | 0 | 3.1250000 | 4.0320428 | SLC5A7 |
| 171 | peptide hormone binding (GO:0017046) | 1/33 | 0.2824605 | 1.0000000 | 0 | 0 | 3.0303030 | 3.8309588 | MC4R |
| 172 | lipase activity (GO:0016298) | 2/105 | 0.2827547 | 1.0000000 | 0 | 0 | 1.9047619 | 2.4060489 | PLA2G1B;CCL5 |
| 173 | amino acid binding (GO:0016597) | 2/107 | 0.2901569 | 1.0000000 | 0 | 0 | 1.8691589 | 2.3127732 | DDC;ANXA9 |
| 174 | peptide antigen binding (GO:0042605) | 1/35 | 0.2967634 | 1.0000000 | 0 | 0 | 2.8571429 | 3.4709146 | HLA-DQB2 |
| 175 | scaffold protein binding (GO:0097110) | 1/35 | 0.2967634 | 1.0000000 | 0 | 0 | 2.8571429 | 3.4709146 | GJA1 |
| 176 | carboxy-lyase activity (GO:0016831) | 1/36 | 0.3038081 | 1.0000000 | 0 | 0 | 2.7777778 | 3.3093308 | DDC |
| 177 | cyclic nucleotide binding (GO:0030551) | 1/36 | 0.3038081 | 1.0000000 | 0 | 0 | 2.7777778 | 3.3093308 | CNGA1 |
| 178 | calcium-dependent phospholipid binding (GO:0005544) | 1/36 | 0.3038081 | 1.0000000 | 0 | 0 | 2.7777778 | 3.3093308 | ANXA9 |
| 179 | exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5’-phosphomonoesters (GO:0016796) | 1/37 | 0.3107825 | 1.0000000 | 0 | 0 | 2.7027027 | 3.1585455 | MEIOB |
| 180 | peptidase activator activity (GO:0016504) | 1/37 | 0.3107825 | 1.0000000 | 0 | 0 | 2.7027027 | 3.1585455 | PCOLCE2 |
| 181 | oxygen binding (GO:0019825) | 1/37 | 0.3107825 | 1.0000000 | 0 | 0 | 2.7027027 | 3.1585455 | CYP2F1 |
| 182 | oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor (GO:0016616) | 2/115 | 0.3196498 | 1.0000000 | 0 | 0 | 1.7391304 | 1.9835291 | ADH1C;ADH1B |
| 183 | Rho GTPase activator activity (GO:0005100) | 1/39 | 0.3245236 | 1.0000000 | 0 | 0 | 2.5641026 | 2.8856335 | DLC1 |
| 184 | protein homodimerization activity (GO:0042803) | 8/653 | 0.3300879 | 1.0000000 | 0 | 0 | 1.2251149 | 1.3579128 | NPPC;DMRT1;CCL5;QPRT;ANXA9;KCNK3;RUNX1T1;ABCG2 |
| 185 | protein self-association (GO:0043621) | 1/40 | 0.3312915 | 1.0000000 | 0 | 0 | 2.5000000 | 2.7618913 | CCL5 |
| 186 | inorganic anion transmembrane transporter activity (GO:0015103) | 2/119 | 0.3342935 | 1.0000000 | 0 | 0 | 1.6806723 | 1.8415730 | GABRD;CLCA4 |
| 187 | SH3 domain binding (GO:0017124) | 2/119 | 0.3342935 | 1.0000000 | 0 | 0 | 1.6806723 | 1.8415730 | GJA1;SKAP1 |
| 188 | phosphatidylinositol-4,5-bisphosphate binding (GO:0005546) | 1/41 | 0.3379920 | 1.0000000 | 0 | 0 | 2.4390244 | 2.6456903 | KCNJ1 |
| 189 | growth factor receptor binding (GO:0070851) | 2/121 | 0.3415820 | 1.0000000 | 0 | 0 | 1.6528926 | 1.7754835 | FGF9;FGF18 |
| 190 | protein kinase regulator activity (GO:0019887) | 2/121 | 0.3415820 | 1.0000000 | 0 | 0 | 1.6528926 | 1.7754835 | CAMK2N1;CCL5 |
| 191 | receptor regulator activity (GO:0030545) | 1/42 | 0.3446257 | 1.0000000 | 0 | 0 | 2.3809524 | 2.5364201 | CCL5 |
| 192 | neuropeptide receptor activity (GO:0008188) | 1/43 | 0.3511932 | 1.0000000 | 0 | 0 | 2.3255814 | 2.4335320 | NPBWR1 |
| 193 | antigen binding (GO:0003823) | 3/212 | 0.3560832 | 1.0000000 | 0 | 0 | 1.4150943 | 1.4612135 | IGHG4;HLA-DOA;HLA-DQB2 |
| 194 | cytokine activity (GO:0005125) | 3/213 | 0.3588085 | 1.0000000 | 0 | 0 | 1.4084507 | 1.4436149 | CCL5;SCGB3A1;SLURP1 |
| 195 | 3’-5’ exonuclease activity (GO:0008408) | 1/45 | 0.3641324 | 1.0000000 | 0 | 0 | 2.2222222 | 2.2449725 | MEIOB |
| 196 | sodium ion transmembrane transporter activity (GO:0015081) | 2/128 | 0.3668834 | 1.0000000 | 0 | 0 | 1.5625000 | 1.5667361 | SLC5A7;SLC6A13 |
| 197 | protein tyrosine/serine/threonine phosphatase activity (GO:0008138) | 1/46 | 0.3705054 | 1.0000000 | 0 | 0 | 2.1739130 | 2.1584503 | DUSP26 |
| 198 | chemokine activity (GO:0008009) | 1/47 | 0.3768149 | 1.0000000 | 0 | 0 | 2.1276596 | 2.0765984 | CCL5 |
| 199 | anion:cation symporter activity (GO:0015296) | 1/48 | 0.3830614 | 1.0000000 | 0 | 0 | 2.0833333 | 1.9990833 | SLC6A13 |
| 200 | protein heterodimerization activity (GO:0046982) | 5/408 | 0.3869998 | 1.0000000 | 0 | 0 | 1.2254902 | 1.1633960 | ROBO2;SCUBE1;DMRT1;JAM2;KCNK3 |
| 201 | protein kinase activator activity (GO:0030295) | 1/49 | 0.3892456 | 1.0000000 | 0 | 0 | 2.0408163 | 1.9256015 | CCL5 |
| 202 | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors (GO:0016706) | 1/49 | 0.3892456 | 1.0000000 | 0 | 0 | 2.0408163 | 1.9256015 | P4HA3 |
| 203 | SH3/SH2 adaptor activity (GO:0005070) | 1/50 | 0.3953682 | 1.0000000 | 0 | 0 | 2.0000000 | 1.8558758 | SKAP1 |
| 204 | carbon-carbon lyase activity (GO:0016830) | 1/51 | 0.4014296 | 1.0000000 | 0 | 0 | 1.9607843 | 1.7896531 | DDC |
| 205 | kinase regulator activity (GO:0019207) | 2/141 | 0.4128121 | 1.0000000 | 0 | 0 | 1.4184397 | 1.2549827 | CAMK2N1;CCL5 |
| 206 | double-stranded RNA binding (GO:0003725) | 1/53 | 0.4133717 | 1.0000000 | 0 | 0 | 1.8867925 | 1.6668075 | OASL |
| 207 | transferase activity, transferring pentosyl groups (GO:0016763) | 1/53 | 0.4133717 | 1.0000000 | 0 | 0 | 1.8867925 | 1.6668075 | QPRT |
| 208 | modified amino acid binding (GO:0072341) | 1/53 | 0.4133717 | 1.0000000 | 0 | 0 | 1.8867925 | 1.6668075 | ANXA9 |
| 209 | protein kinase inhibitor activity (GO:0004860) | 1/54 | 0.4192536 | 1.0000000 | 0 | 0 | 1.8518519 | 1.6097765 | CAMK2N1 |
| 210 | kinase activator activity (GO:0019209) | 1/55 | 0.4250768 | 1.0000000 | 0 | 0 | 1.8181818 | 1.5554281 | CCL5 |
| 211 | repressing transcription factor binding (GO:0070491) | 1/55 | 0.4250768 | 1.0000000 | 0 | 0 | 1.8181818 | 1.5554281 | HLA-DQB2 |
| 212 | phosphatidylinositol bisphosphate binding (GO:1902936) | 1/56 | 0.4308418 | 1.0000000 | 0 | 0 | 1.7857143 | 1.5035968 | KCNJ1 |
| 213 | oxidoreductase activity, acting on the CH-CH group of donors (GO:0016627) | 1/56 | 0.4308418 | 1.0000000 | 0 | 0 | 1.7857143 | 1.5035968 | ACOXL |
| 214 | steroid hormone receptor activity (GO:0003707) | 1/57 | 0.4365494 | 1.0000000 | 0 | 0 | 1.7543860 | 1.4541294 | OR51E2 |
| 215 | pyridoxal phosphate binding (GO:0030170) | 1/57 | 0.4365494 | 1.0000000 | 0 | 0 | 1.7543860 | 1.4541294 | DDC |
| 216 | chemokine receptor binding (GO:0042379) | 1/57 | 0.4365494 | 1.0000000 | 0 | 0 | 1.7543860 | 1.4541294 | CCL5 |
| 217 | kinase inhibitor activity (GO:0019210) | 1/57 | 0.4365494 | 1.0000000 | 0 | 0 | 1.7543860 | 1.4541294 | CAMK2N1 |
| 218 | deoxyribonuclease activity (GO:0004536) | 1/57 | 0.4365494 | 1.0000000 | 0 | 0 | 1.7543860 | 1.4541294 | MEIOB |
| 219 | antiporter activity (GO:0015297) | 1/62 | 0.4642441 | 1.0000000 | 0 | 0 | 1.6129032 | 1.2376529 | SLC4A10 |
| 220 | cargo receptor activity (GO:0038024) | 1/62 | 0.4642441 | 1.0000000 | 0 | 0 | 1.6129032 | 1.2376529 | LRP1B |
| 221 | hormone binding (GO:0042562) | 1/62 | 0.4642441 | 1.0000000 | 0 | 0 | 1.6129032 | 1.2376529 | MC4R |
| 222 | hormone receptor binding (GO:0051427) | 2/160 | 0.4768118 | 1.0000000 | 0 | 0 | 1.2500000 | 0.9257918 | NPPC;OASL |
| 223 | transmembrane receptor protein tyrosine kinase activity (GO:0004714) | 1/65 | 0.4802063 | 1.0000000 | 0 | 0 | 1.5384615 | 1.1285222 | FLT4 |
| 224 | growth factor activity (GO:0008083) | 2/163 | 0.4865301 | 1.0000000 | 0 | 0 | 1.2269939 | 0.8839957 | FGF9;FGF18 |
| 225 | signaling adaptor activity (GO:0035591) | 1/67 | 0.4905840 | 1.0000000 | 0 | 0 | 1.4925373 | 1.0629235 | SKAP1 |
| 226 | extracellular matrix structural constituent (GO:0005201) | 1/68 | 0.4956953 | 1.0000000 | 0 | 0 | 1.4705882 | 1.0320498 | FBN1 |
| 227 | endopeptidase inhibitor activity (GO:0004866) | 2/166 | 0.4961360 | 1.0000000 | 0 | 0 | 1.2048193 | 0.8444640 | PROS1;A2ML1 |
| 228 | endopeptidase regulator activity (GO:0061135) | 2/171 | 0.5118910 | 1.0000000 | 0 | 0 | 1.1695906 | 0.7832088 | PROS1;A2ML1 |
| 229 | peptide binding (GO:0042277) | 2/172 | 0.5150033 | 1.0000000 | 0 | 0 | 1.1627907 | 0.7716070 | MC4R;HLA-DQB2 |
| 230 | core promoter proximal region sequence-specific DNA binding (GO:0000987) | 2/176 | 0.5273210 | 1.0000000 | 0 | 0 | 1.1363636 | 0.7272111 | DMRT1;FEZF2 |
| 231 | exonuclease activity (GO:0004527) | 1/75 | 0.5300734 | 1.0000000 | 0 | 0 | 1.3333333 | 0.8463198 | MEIOB |
| 232 | amide binding (GO:0033218) | 2/177 | 0.5303674 | 1.0000000 | 0 | 0 | 1.1299435 | 0.7165935 | MC4R;HLA-DQB2 |
| 233 | core promoter proximal region DNA binding (GO:0001159) | 2/178 | 0.5334006 | 1.0000000 | 0 | 0 | 1.1235955 | 0.7061602 | DMRT1;FEZF2 |
| 234 | single-stranded DNA binding (GO:0003697) | 1/76 | 0.5347903 | 1.0000000 | 0 | 0 | 1.3157895 | 0.8235271 | MEIOB |
| 235 | microtubule motor activity (GO:0003777) | 1/78 | 0.5440833 | 1.0000000 | 0 | 0 | 1.2820513 | 0.7803242 | KIF12 |
| 236 | small conjugating protein ligase binding (GO:0044389) | 2/182 | 0.5453994 | 1.0000000 | 0 | 0 | 1.0989011 | 0.6661944 | MC4R;HLA-DQB2 |
| 237 | ubiquitin protein ligase binding (GO:0031625) | 2/182 | 0.5453994 | 1.0000000 | 0 | 0 | 1.0989011 | 0.6661944 | MC4R;HLA-DQB2 |
| 238 | vitamin binding (GO:0019842) | 1/80 | 0.5531916 | 1.0000000 | 0 | 0 | 1.2500000 | 0.7400636 | P4HA3 |
| 239 | protein transporter activity (GO:0008565) | 1/81 | 0.5576776 | 1.0000000 | 0 | 0 | 1.2345679 | 0.7209558 | RAMP2 |
| 240 | acid-amino acid ligase activity (GO:0016881) | 1/81 | 0.5576776 | 1.0000000 | 0 | 0 | 1.2345679 | 0.7209558 | UBE2QL1 |
| 241 | glycoprotein binding (GO:0001948) | 1/81 | 0.5576776 | 1.0000000 | 0 | 0 | 1.2345679 | 0.7209558 | GPC3 |
| 242 | transmembrane receptor protein kinase activity (GO:0019199) | 1/82 | 0.5621188 | 1.0000000 | 0 | 0 | 1.2195122 | 0.7024903 | FLT4 |
| 243 | steroid binding (GO:0005496) | 1/82 | 0.5621188 | 1.0000000 | 0 | 0 | 1.2195122 | 0.7024903 | PLA2G1B |
| 244 | lipid transporter activity (GO:0005319) | 1/87 | 0.5836680 | 1.0000000 | 0 | 0 | 1.1494253 | 0.6188770 | FABP3 |
| 245 | endopeptidase activity (GO:0004175) | 4/411 | 0.5909584 | 1.0000000 | 0 | 0 | 0.9732360 | 0.5119315 | TMPRSS11A;PRSS27;TMPRSS11E;TMPRSS11F |
| 246 | alcohol binding (GO:0043178) | 1/89 | 0.5919892 | 1.0000000 | 0 | 0 | 1.1235955 | 0.5890639 | SLC5A7 |
| 247 | phosphoric diester hydrolase activity (GO:0008081) | 1/90 | 0.5960875 | 1.0000000 | 0 | 0 | 1.1111111 | 0.5748531 | CCL5 |
| 248 | phosphatidylinositol phosphate binding (GO:1901981) | 1/91 | 0.6001449 | 1.0000000 | 0 | 0 | 1.0989011 | 0.5610815 | KCNJ1 |
| 249 | PDZ domain binding (GO:0030165) | 1/96 | 0.6198314 | 1.0000000 | 0 | 0 | 1.0416667 | 0.4982372 | GJA1 |
| 250 | serine-type endopeptidase inhibitor activity (GO:0004867) | 1/98 | 0.6274332 | 1.0000000 | 0 | 0 | 1.0204082 | 0.4756306 | A2ML1 |
| 251 | unfolded protein binding (GO:0051082) | 1/101 | 0.6385533 | 1.0000000 | 0 | 0 | 0.9900990 | 0.4441090 | SCG5 |
| 252 | integrin binding (GO:0005178) | 1/102 | 0.6421861 | 1.0000000 | 0 | 0 | 0.9803922 | 0.4341933 | ECM2 |
| 253 | protein tyrosine phosphatase activity (GO:0004725) | 1/103 | 0.6457826 | 1.0000000 | 0 | 0 | 0.9708738 | 0.4245557 | DUSP26 |
| 254 | ATPase activity, coupled to transmembrane movement of substances (GO:0042626) | 1/104 | 0.6493431 | 1.0000000 | 0 | 0 | 0.9615385 | 0.4151866 | ABCG2 |
| 255 | ATPase activity, coupled to movement of substances (GO:0043492) | 1/105 | 0.6528680 | 1.0000000 | 0 | 0 | 0.9523810 | 0.4060766 | ABCG2 |
| 256 | calcium channel activity (GO:0005262) | 1/108 | 0.6632325 | 1.0000000 | 0 | 0 | 0.9259259 | 0.3802127 | GPM6A |
| 257 | hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances (GO:0016820) | 1/108 | 0.6632325 | 1.0000000 | 0 | 0 | 0.9259259 | 0.3802127 | ABCG2 |
| 258 | double-stranded DNA binding (GO:0003690) | 1/109 | 0.6666184 | 1.0000000 | 0 | 0 | 0.9174312 | 0.3720527 | HLF |
| 259 | G-protein coupled receptor binding (GO:0001664) | 2/229 | 0.6700506 | 1.0000000 | 0 | 0 | 0.8733624 | 0.3496962 | KISS1;CCL5 |
| 260 | primary active transmembrane transporter activity (GO:0015399) | 1/111 | 0.6732890 | 1.0000000 | 0 | 0 | 0.9009009 | 0.3563789 | ABCG2 |
| 261 | P-P-bond-hydrolysis-driven transmembrane transporter activity (GO:0015405) | 1/111 | 0.6732890 | 1.0000000 | 0 | 0 | 0.9009009 | 0.3563789 | ABCG2 |
| 262 | carboxylic ester hydrolase activity (GO:0052689) | 1/111 | 0.6732890 | 1.0000000 | 0 | 0 | 0.9009009 | 0.3563789 | PLA2G1B |
| 263 | transcription factor binding (GO:0008134) | 4/464 | 0.6851836 | 1.0000000 | 0 | 0 | 0.8620690 | 0.3259211 | BEX1;DUSP26;HLA-DQB2;OASL |
| 264 | ligase activity, forming carbon-nitrogen bonds (GO:0016879) | 1/117 | 0.6925144 | 1.0000000 | 0 | 0 | 0.8547009 | 0.3140395 | UBE2QL1 |
| 265 | structure-specific DNA binding (GO:0043566) | 2/241 | 0.6971041 | 1.0000000 | 0 | 0 | 0.8298755 | 0.2994361 | HLF;MEIOB |
| 266 | hormone activity (GO:0005179) | 1/122 | 0.7076726 | 1.0000000 | 0 | 0 | 0.8196721 | 0.2834211 | NPPC |
| 267 | growth factor binding (GO:0019838) | 1/123 | 0.7106138 | 1.0000000 | 0 | 0 | 0.8130081 | 0.2777449 | FLT4 |
| 268 | receptor signaling protein activity (GO:0005057) | 1/124 | 0.7135255 | 1.0000000 | 0 | 0 | 0.8064516 | 0.2722073 | DOK5 |
| 269 | Ras GTPase activator activity (GO:0005099) | 1/124 | 0.7135255 | 1.0000000 | 0 | 0 | 0.8064516 | 0.2722073 | DLC1 |
| 270 | kinase binding (GO:0019900) | 4/487 | 0.7210317 | 1.0000000 | 0 | 0 | 0.8213552 | 0.2686424 | CAMK2N1;DCX;SKAP1;JAKMIP2 |
| 271 | calcium ion transmembrane transporter activity (GO:0015085) | 1/127 | 0.7220870 | 1.0000000 | 0 | 0 | 0.7874016 | 0.2563855 | GPM6A |
| 272 | motor activity (GO:0003774) | 1/132 | 0.7357941 | 1.0000000 | 0 | 0 | 0.7575758 | 0.2324280 | KIF12 |
| 273 | protein binding, bridging (GO:0030674) | 1/134 | 0.7410867 | 1.0000000 | 0 | 0 | 0.7462687 | 0.2236102 | SKAP1 |
| 274 | cofactor binding (GO:0048037) | 2/266 | 0.7475973 | 1.0000000 | 0 | 0 | 0.7518797 | 0.2187149 | DDC;HHIP |
| 275 | nuclear hormone receptor binding (GO:0035257) | 1/139 | 0.7538610 | 1.0000000 | 0 | 0 | 0.7194245 | 0.2032714 | OASL |
| 276 | nucleotidyltransferase activity (GO:0016779) | 1/140 | 0.7563396 | 1.0000000 | 0 | 0 | 0.7142857 | 0.1994748 | OASL |
| 277 | protein tyrosine kinase activity (GO:0004713) | 1/142 | 0.7612226 | 1.0000000 | 0 | 0 | 0.7042254 | 0.1921334 | FLT4 |
| 278 | binding, bridging (GO:0060090) | 1/146 | 0.7706983 | 1.0000000 | 0 | 0 | 0.6849315 | 0.1783961 | SKAP1 |
| 279 | transferase activity, transferring glycosyl groups (GO:0016757) | 2/280 | 0.7726084 | 1.0000000 | 0 | 0 | 0.7142857 | 0.1842735 | ST6GAL2;QPRT |
| 280 | guanyl ribonucleotide binding (GO:0032561) | 3/405 | 0.7735836 | 1.0000000 | 0 | 0 | 0.7407407 | 0.1901641 | DIRAS2;SCG5;CNGA1 |
| 281 | guanyl nucleotide binding (GO:0019001) | 3/406 | 0.7750152 | 1.0000000 | 0 | 0 | 0.7389163 | 0.1883295 | DIRAS2;SCG5;CNGA1 |
| 282 | divalent inorganic cation transmembrane transporter activity (GO:0072509) | 1/154 | 0.7885417 | 1.0000000 | 0 | 0 | 0.6493506 | 0.1542663 | GPM6A |
| 283 | phospholipid binding (GO:0005543) | 2/296 | 0.7985326 | 1.0000000 | 0 | 0 | 0.6756757 | 0.1520132 | ANXA9;KCNJ1 |
| 284 | isomerase activity (GO:0016853) | 1/159 | 0.7989850 | 1.0000000 | 0 | 0 | 0.6289308 | 0.1411403 | ALOX12 |
| 285 | protein C-terminus binding (GO:0008022) | 1/162 | 0.8050029 | 1.0000000 | 0 | 0 | 0.6172840 | 0.1338947 | KCNK3 |
| 286 | RNA polymerase II core promoter proximal region sequence-specific DNA binding (GO:0000978) | 1/167 | 0.8146371 | 1.0000000 | 0 | 0 | 0.5988024 | 0.1227620 | FEZF2 |
| 287 | protein kinase binding (GO:0019901) | 3/437 | 0.8158405 | 1.0000000 | 0 | 0 | 0.6864989 | 0.1397275 | CAMK2N1;DCX;SKAP1 |
| 288 | cell adhesion molecule binding (GO:0050839) | 1/168 | 0.8165063 | 1.0000000 | 0 | 0 | 0.5952381 | 0.1206671 | ECM2 |
| 289 | phosphoprotein phosphatase activity (GO:0004721) | 1/172 | 0.8237975 | 1.0000000 | 0 | 0 | 0.5813953 | 0.1126922 | DUSP26 |
| 290 | cysteine-type peptidase activity (GO:0008234) | 1/172 | 0.8237975 | 1.0000000 | 0 | 0 | 0.5813953 | 0.1126922 | CTSW |
| 291 | enzyme activator activity (GO:0008047) | 3/446 | 0.8264580 | 1.0000000 | 0 | 0 | 0.6726457 | 0.1282104 | PCOLCE2;DLC1;CCL5 |
| 292 | lyase activity (GO:0016829) | 1/177 | 0.8325073 | 1.0000000 | 0 | 0 | 0.5649718 | 0.1035668 | DDC |
| 293 | phosphatidylinositol binding (GO:0035091) | 1/178 | 0.8341972 | 1.0000000 | 0 | 0 | 0.5617978 | 0.1018458 | KCNJ1 |
| 294 | metallopeptidase activity (GO:0008237) | 1/188 | 0.8501902 | 1.0000000 | 0 | 0 | 0.5319149 | 0.0863272 | ADAMTSL1 |
| 295 | transcription regulatory region sequence-specific DNA binding (GO:0000976) | 2/340 | 0.8568359 | 1.0000000 | 0 | 0 | 0.5882353 | 0.0908876 | DMRT1;FEZF2 |
| 296 | nuclease activity (GO:0004518) | 1/195 | 0.8604625 | 1.0000000 | 0 | 0 | 0.5128205 | 0.0770693 | MEIOB |
| 297 | small GTPase regulator activity (GO:0005083) | 1/195 | 0.8604625 | 1.0000000 | 0 | 0 | 0.5128205 | 0.0770693 | DLC1 |
| 298 | phosphoric ester hydrolase activity (GO:0042578) | 2/360 | 0.8778898 | 1.0000000 | 0 | 0 | 0.5555556 | 0.0723523 | CCL5;DUSP26 |
| 299 | GTP binding (GO:0005525) | 2/385 | 0.9002020 | 1.0000000 | 0 | 0 | 0.5194805 | 0.0546161 | DIRAS2;SCG5 |
| 300 | cytokine receptor binding (GO:0005126) | 1/228 | 0.9002045 | 1.0000000 | 0 | 0 | 0.4385965 | 0.0461111 | CCL5 |
| 301 | ATPase activity (GO:0016887) | 2/395 | 0.9080188 | 1.0000000 | 0 | 0 | 0.5063291 | 0.0488558 | KIF12;ABCG2 |
| 302 | transferase activity, transferring acyl groups (GO:0016746) | 1/243 | 0.9143243 | 1.0000000 | 0 | 0 | 0.4115226 | 0.0368601 | TGM3 |
| 303 | chromatin binding (GO:0003682) | 2/420 | 0.9251344 | 1.0000000 | 0 | 0 | 0.4761905 | 0.0370554 | DMRT1;MEIOB |
| 304 | GTPase activator activity (GO:0005096) | 1/265 | 0.9315150 | 1.0000000 | 0 | 0 | 0.3773585 | 0.0267709 | DLC1 |
| 305 | phosphatase activity (GO:0016791) | 1/266 | 0.9322090 | 1.0000000 | 0 | 0 | 0.3759398 | 0.0263903 | DUSP26 |
| 306 | ATPase activity, coupled (GO:0042623) | 1/272 | 0.9362286 | 1.0000000 | 0 | 0 | 0.3676471 | 0.0242263 | ABCG2 |
| 307 | zinc ion binding (GO:0008270) | 8/1256 | 0.9391936 | 1.0000000 | 0 | 0 | 0.6369427 | 0.0399577 | ADAMTSL1;APOBEC2;ADH1C;APOBEC3H;ADH1B;HHIP;PEG10;ZNF385B |
| 308 | RNA polymerase II regulatory region sequence-specific DNA binding (GO:0000977) | 1/284 | 0.9435701 | 1.0000000 | 0 | 0 | 0.3521127 | 0.0204523 | FEZF2 |
| 309 | RNA polymerase II regulatory region DNA binding (GO:0001012) | 1/288 | 0.9458253 | 1.0000000 | 0 | 0 | 0.3472222 | 0.0193394 | FEZF2 |
| 310 | GTPase regulator activity (GO:0030695) | 1/310 | 0.9567174 | 1.0000000 | 0 | 0 | 0.3225806 | 0.0142733 | DLC1 |
| 311 | nucleoside-triphosphatase regulator activity (GO:0060589) | 1/330 | 0.9647144 | 1.0000000 | 0 | 0 | 0.3030303 | 0.0108858 | DLC1 |
| 312 | olfactory receptor activity (GO:0004984) | 1/420 | 0.9859630 | 1.0000000 | 0 | 0 | 0.2380952 | 0.0033658 | OR51E2 |
| 313 | ligase activity (GO:0016874) | 1/431 | 0.9874621 | 1.0000000 | 0 | 0 | 0.2320186 | 0.0029274 | UBE2QL1 |
| 314 | ATP binding (GO:0005524) | 6/1494 | 0.9978601 | 1.0000000 | 0 | 0 | 0.4016064 | 0.0008603 | FLT4;UBE2QL1;KIF12;KCNJ1;ABCG2;OASL |
For reproducibility:
## datetime
Sys.time()
## [1] "2020-12-08 14:37:05 EST"
## session info
sessionInfo()
## R version 4.0.2 (2020-06-22)
## Platform: x86_64-pc-linux-gnu (64-bit)
## Running under: CentOS Linux 7 (Core)
##
## Matrix products: default
## BLAS: /share/pkg.7/r/4.0.2/install/lib/libopenblasp-r0.3.7.so
## LAPACK: /share/pkg.7/r/4.0.2/install/lib/liblapack.so.3.9.0
##
## locale:
## [1] C
##
## attached base packages:
## [1] parallel stats4 stats graphics grDevices utils datasets
## [8] methods base
##
## other attached packages:
## [1] limma_3.46.0 affy_1.68.0
## [3] biomaRt_2.46.0 enrichR_2.1
## [5] kableExtra_1.3.1 knitr_1.30
## [7] DESeq2_1.30.0 RColorBrewer_1.1-2
## [9] pheatmap_1.0.12 ggplot2_3.3.2
## [11] dplyr_1.0.2 readxl_1.3.1
## [13] SummarizedExperiment_1.20.0 Biobase_2.50.0
## [15] GenomicRanges_1.42.0 GenomeInfoDb_1.26.0
## [17] IRanges_2.24.0 S4Vectors_0.28.0
## [19] BiocGenerics_0.36.0 MatrixGenerics_1.2.0
## [21] matrixStats_0.57.0 plyr_1.8.6
## [23] rmarkdown_2.5
##
## loaded via a namespace (and not attached):
## [1] bitops_1.0-6 bit64_4.0.5 webshot_0.5.2
## [4] progress_1.2.2 httr_1.4.2 tools_4.0.2
## [7] R6_2.5.0 affyio_1.60.0 DBI_1.1.0
## [10] colorspace_2.0-0 withr_2.3.0 tidyselect_1.1.0
## [13] prettyunits_1.1.1 bit_4.0.4 curl_4.3
## [16] compiler_4.0.2 preprocessCore_1.52.0 rvest_0.3.6
## [19] xml2_1.3.2 DelayedArray_0.16.0 labeling_0.4.2
## [22] scales_1.1.1 genefilter_1.72.0 askpass_1.1
## [25] rappdirs_0.3.1 stringr_1.4.0 digest_0.6.27
## [28] XVector_0.30.0 pkgconfig_2.0.3 htmltools_0.5.0
## [31] dbplyr_2.0.0 highr_0.8 rlang_0.4.8
## [34] rstudioapi_0.13 RSQLite_2.2.1 farver_2.0.3
## [37] generics_0.1.0 BiocParallel_1.24.1 RCurl_1.98-1.2
## [40] magrittr_2.0.1 GenomeInfoDbData_1.2.4 Matrix_1.2-18
## [43] Rcpp_1.0.5 munsell_0.5.0 lifecycle_0.2.0
## [46] stringi_1.5.3 yaml_2.2.1 zlibbioc_1.36.0
## [49] BiocFileCache_1.14.0 grid_4.0.2 blob_1.2.1
## [52] crayon_1.3.4 lattice_0.20-41 splines_4.0.2
## [55] annotate_1.68.0 hms_0.5.3 locfit_1.5-9.4
## [58] pillar_1.4.6 rjson_0.2.20 geneplotter_1.68.0
## [61] XML_3.99-0.5 glue_1.4.2 evaluate_0.14
## [64] BiocManager_1.30.10 vctrs_0.3.5 cellranger_1.1.0
## [67] gtable_0.3.0 openssl_1.4.3 purrr_0.3.4
## [70] assertthat_0.2.1 xfun_0.19 xtable_1.8-4
## [73] survival_3.1-12 viridisLite_0.3.0 tibble_3.0.4
## [76] AnnotationDbi_1.52.0 memoise_1.1.0 ellipsis_0.3.1